# Game Changer Grant

**Funder:** ChadTough DIPG Foundation
**Budget:** Up to $600,000 over 3 years (max $200,000/year)
**Deadline:** 11 January 2027 (Call opens 16 October 2026; LOI due date shown as deadline)
**Duration:** 3 years
**Consortium:** No - individual applicant
**Application:** LOI → invitation for full submission → full application (LOI due 11 January 2027, invitation 24 February 2027, full application due 31 March 2027)
**Frequency:** Annual
**Next round:** 2026-10
**Official call:** https://chadtough.org/research/grant-application/
**Last updated:** 6 Sept 2026

> **Recently updated:** catalog cleanup 2026-07-04: duplicate row (canonical sibling kept)

## Eligibility & scope

Funds hypothesis-driven, innovative research projects addressing major challenges in DIPG/DMG research with potential for groundbreaking discoveries. Application via Proposal Central; opens 16 October 2026.

## Summary

The ChadTough DIPG Foundation Game Changer Grant funds established DIPG researchers pursuing innovative approaches to major challenges in the field, with up to $600,000 over three years. The call is open to researchers at institutions globally who have existing DIPG research programs. Note: the current round has been awarded; prospective applicants should check the foundation's grant application page for the next cycle timeline.

## Who should apply

- Established researchers with an active DIPG research program
- Researchers at academic, hospital, or research institutions globally
- Projects proposing innovative approaches to unmet DIPG research challenges
- Investigators seeking to advance understanding of DIPG biology or treatment

## Key dates

- Three-year project funding period
- Next cycle timing not yet announced; check the foundation's grant page for updates

## Tips for applicants

- ChadTough prioritizes innovation and patient impact; frame your approach as a genuine departure from the field's current direction.
- Emphasize how your project addresses one of the major bottlenecks in DIPG research, the foundation funds solutions, not incremental work.
- Include support letters from collaborators or institutional leadership demonstrating buy-in for your proposed approach.

## Frequently asked questions

### How much does the ChadTough Game Changer Grant pay?

Up to $600,000 over three years per project.

### Who is eligible for the ChadTough Game Changer Grant?

Established DIPG researchers with an active research program at institutions globally.

### Is the ChadTough Game Changer Grant currently open?

The current award round has been completed; check the ChadTough grant application page for the timing of the next cycle.

### What kind of research does ChadTough Game Changer fund?

Innovative approaches to major unresolved challenges in DIPG research, including biology, clinical translation, and treatment development.

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Source: [The Great Grantsby](https://grantsby.eu/grants/chadtough-dipg-foundation-game-changer-grant-research-grant-2026) — EU grant monitoring for academic researchers. Always verify details on the funder's website before applying.

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