# Priority Programme „Integration of mitochondria into the cellular proteostasis network” (SPP 2453)

**Funder:** DFG
**Deadline:** 27 January 2027 (Registration in elan portal required by 20 January 2027 for first-time applicants)
**Duration:** 3 years (second funding period of a six-year programme)
**Consortium:** Required — tandem or tridem projects combining expertise from mitochondrial protein import and cellular proteostasis fields
**Application:** Single stage: proposal submission via elan portal for new or renewal projects within the Priority Programme
**Frequency:** One-off
**Eligible countries:** DE
**Official call:** https://www.dfg.de/en/news/news-topics/announcements-proposals/2026/ifr-26-77
**Last updated:** 18 Oct 2026

## Eligibility & scope

Call for the second three-year funding period of Priority Programme SPP 2453 on mitochondrial protein import and cellular proteostasis. Proposals must be written in English and submitted via the elan portal; only tandem/tridem projects combining mitochondrial import and proteostasis expertise using yeast, C. elegans or mammalian cell models are funded. Review colloquium 7–9 April 2027 in Bonn.

## Summary

DFG Priority Programme SPP 2453 funds collaborative research on how mitochondria integrate into the cellular proteostasis network, for its second three-year funding period. The call supports tandem or tridem projects that combine mitochondrial protein import expertise with cellular proteostasis expertise, using yeast, C. elegans or mammalian cell models. Only researchers at German institutions are eligible, and proposals must be submitted jointly by collaborating teams rather than single investigators.

## Who should apply

- Researchers at German universities or research institutions
- Teams combining mitochondrial protein import expertise with cellular proteostasis expertise
- Groups working with yeast, C. elegans or mammalian cell models
- Applicants forming tandem (two-PI) or tridem (three-PI) collaborative proposals
- First-time applicants must register in the elan portal ahead of submission

## Key dates

- Proposal deadline: 27 January 2027
- First-time applicants must register in the elan portal by 20 January 2027
- Three-year funding period (second phase of a six-year programme); review colloquium 7-9 April 2027 in Bonn

## Tips for applicants

- Proposals must be written in English and framed explicitly as a tandem or tridem collaboration, single-PI submissions are not funded under this call.
- Register early in the elan portal, since first-time applicants face a separate registration deadline a week before submission closes.
- Clearly show how the mitochondrial import and proteostasis expertise of each partner is integrated, since the call funds this combination specifically rather than either topic alone.

## Frequently asked questions

### Who can apply to DFG SPP 2453?

Researchers at German institutions working on mitochondrial protein import or cellular proteostasis, applying jointly as tandem or tridem teams.

### How long is the SPP 2453 funding period?

Three years, covering the second funding period of the six-year Priority Programme.

### Do I need a consortium to apply?

Yes, only tandem (two-partner) or tridem (three-partner) projects combining mitochondrial import and proteostasis expertise are funded.

### What is the deadline for SPP 2453?

Proposals are due 27 January 2027, and first-time applicants must register in the elan portal by 20 January 2027.

### Is there an interview or colloquium for SPP 2453?

Yes, a review colloquium is scheduled for 7-9 April 2027 in Bonn.

---

Source: [The Great Grantsby](https://grantsby.eu/grants/dfg-priority-programme-integration-of-mitochondria-int-2027-01) — EU grant monitoring for academic researchers. Always verify details on the funder's website before applying.

**See which EU calls match your profile.** [Preview your matches in 30 seconds, no signup](https://grantsby.eu/demo?ref=llm_grant_md&grant=dfg-priority-programme-integration-of-mitochondria-int-2027-01).