# US-Ireland Research and Development Partnership Programme

**Funder:** HRB
**Consortium:** Required — minimum 1 applicant from each of 3 jurisdictions (USA, Republic of Ireland, Northern Ireland)
**Application:** 2-stage: Intention to Submit form → joint tri-partite full proposal submitted to NIH
**Frequency:** Continuous
**Eligible countries:** US, IE, GB
**Official call:** https://www.hrb.ie/funding-scheme/us-ireland-research-and-development-partnership-programme/
**Last verified:** 12 July 2026

## Eligibility & scope

Tri-jurisdictional collaborative R&D programme (USA, Republic of Ireland, Northern Ireland) covering the full NIH remit. Requires mid-stage or senior career researchers; at least one applicant per jurisdiction. Proposals submitted in NIH RO1 format. ROI applicants managed via Research Ireland in consultation with HRB. Host institution signatory approval required before submission.

## Summary

The US-Ireland Research and Development Partnership Programme funds collaborative biomedical and life sciences research across the USA, Republic of Ireland, and Northern Ireland through a tri-jurisdictional consortium model. Mid-career and senior researchers can apply through a two-stage process, with proposals submitted in NIH RO1 format and managed by HRB and Research Ireland. The call operates continuously, requiring minimum participation from all three jurisdictions and host institution sign-off before submission.

## Who should apply

- Mid-career or senior researchers with established track records
- Applicants based in the USA, Republic of Ireland, or Northern Ireland
- Research teams spanning all three jurisdictions (minimum one PI per jurisdiction)
- Biomedical and life sciences projects within the NIH remit
- Researchers whose host institutions can provide signatory approval

## Key dates

- Full proposal deadline set by NIH (check NIH due dates page for current rounds)
- Intention to Submit form required at least 10 weeks before NIH deadline
- Near-final draft due to Research Ireland/HRB at least 6 weeks before NIH deadline
- Continuous call, apply to any active NIH round

## Tips for applicants

- Consortium setup is gating: confirm co-applicant commitment and institutional sign-off from all three jurisdictions early, before drafting the Intention to Submit form.
- Work backward from the NIH deadline: the HRB/Research Ireland review window (6-10 weeks prior) is tight for tri-jurisdictional feedback loops, begin internal coordination at least 12-14 weeks out.
- Proposals must fit NIH RO1 scope and review criteria; UK and Irish applicants should familiarise themselves with current NIH paylines and study section expectations, as panel feedback often leans heavily on feasibility and preliminary data strength.

## Frequently asked questions

### What is the consortium requirement for the US-Ireland R&D Partnership?

A minimum of one applicant from each of the three jurisdictions (USA, Republic of Ireland, Northern Ireland) must be listed on the proposal.

### When do I need to submit my Intention to Submit form?

At least 10 weeks before the NIH full proposal deadline; check the NIH due dates page for the specific round you are targeting.

### What format do proposals use?

Proposals are submitted in NIH RO1 format to the NIH, with tri-jurisdictional management via HRB and Research Ireland.

### Who manages the application for UK and Irish researchers?

ROI applicants are managed via Research Ireland in consultation with HRB; check their guidance for UK (Northern Ireland) applicants separately.

### Is this call annual or continuous?

The call is continuous, researchers can apply to any active NIH funding opportunity round that aligns with the programme's scope.

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Source: [The Great Grantsby](https://grantsby.eu/grants/hrb-us-ireland-research-and-development-partnership-pr-2026) — EU grant monitoring for academic researchers. Always verify details on the funder's website before applying.

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