# Proof of Concept

**Funder:** MRC
**Budget:** No limit stated; 80% FEC funded
**Deadline:** 18 November 2026 (4:00pm UK time)
**Duration:** No limit; projects start 1–6 months after funding decision
**Consortium:** No
**Application:** 2-stage: stage one application → invited stage two
**Eligible countries:** GB
**Official call:** https://www.ukri.org/opportunity/mrc-proof-of-concept-stage-one/
**Last verified:** 5 July 2026

## Eligibility & scope

Academically-led translational projects developing novel therapeutics, devices, diagnostics or interventions from early prototype through to phase 2a clinical studies. Project lead must be employed by an eligible UK research organisation; international researchers may participate as project co-lead (international). Funds 80% FEC; no matched funding required beyond standard 20% FEC.

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Source: [The Great Grantsby](https://grantsby.eu/grants/mrc-proof-of-concept-2026-11) — EU grant monitoring for academic researchers. Always verify details on the funder's website before applying.