# Reducing Central Line-Associated Bloodstream Infections in Neonates

**Funder:** NIHR
**Application:** 2-stage: outline application → full application
**Frequency:** One-off
**Eligible countries:** GB
**Official call:** https://www.nihr.ac.uk/funding/reducing-central-line-associated-bloodstream-infections-neonates/2026475
**Last updated:** 16 Aug 2026

## Eligibility & scope

NIHR HTA Programme commissioned call on neonatal central line-associated bloodstream infections. UK-based applicants only; NHS/social care setting required. Multidisciplinary team including health economist and statistician expected. HRA ethics approval required; CTU involvement advised for clinical trials. Proposals must use PICO framework.

## Summary

This is a UK-specific NIHR HTA Programme call commissioning research on reducing central line-associated bloodstream infections (CLABSIs) in neonates. The call targets multidisciplinary teams based in NHS or social care settings, requiring clinical, health economics, and statistics expertise to address the PICO framework with patient-centred outcomes and cost-effectiveness analysis. This is a one-off call, not recurring.

## Who should apply

- UK-based researchers and clinical teams embedded in NHS or social care settings
- Multidisciplinary teams spanning clinical practice, health economics, and statistics
- Research teams with capacity to conduct PICO-framed evaluation with cost-effectiveness analysis
- Groups with access to neonatal patient populations and outcome data

## Key dates

- Two-stage process: outline application followed by full application for shortlisted proposals
- One-off commissioning call (not recurring)

## Tips for applicants

- Assemble the multidisciplinary team upfront, clinical, economics, and statistics expertise are gatekeeping, not optional.
- Frame your research squarely within the PICO framework and lead with patient-centred outcomes; cost-effectiveness analysis is mandatory, not supplementary.
- Ensure your outline application clearly anchors the problem in NHS neonatal practice and signals access to relevant populations and data.

## Frequently asked questions

### What is the NIHR HTA Programme call on central line-associated bloodstream infections in neonates?

It is a one-off UK-based commissioned call from NIHR HTA Programme seeking research on reducing CLABSIs in neonates, with a requirement for multidisciplinary teams, NHS/social care settings, and patient-centred outcomes alongside cost-effectiveness analysis.

### Who can apply to this NIHR HTA call?

UK-based applicants based in NHS or social care settings, working in multidisciplinary teams that include clinical, health economics, and statistics expertise.

### Is this NIHR HTA call recurring?

No, this is a one-off commissioned call, not an annual or rolling opportunity.

### What must the research address in this NIHR HTA call?

Research must address the PICO framework with patient-centred outcomes and include a cost-effectiveness analysis.

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Source: [The Great Grantsby](https://grantsby.eu/grants/nihr-reducing-central-line-associated-bloodstream-infec-2026) — EU grant monitoring for academic researchers. Always verify details on the funder's website before applying.

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