[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-erc-proof-of-concept-2016":3,"awarded-stats-erc-proof-of-concept":753},{"awarded":4,"total":752},[5,16,23,28,32,38,44,50,56,61,67,72,77,83,89,95,101,108,113,120,125,131,137,143,148,154,160,166,171,176,181,186,192,199,205,211,217,221,227,232,238,242,246,252,257,261,265,271,276,281,286,291,297,303,309,315,321,328,332,337,343,348,354,360,365,370,375,380,385,390,395,401,407,411,417,422,427,432,436,441,447,451,457,461,466,471,476,482,487,491,497,502,507,512,518,524,529,533,538,543,547,551,557,562,567,572,576,581,586,592,597,602,607,611,616,621,626,631,637,643,649,653,658,663,668,673,678,682,686,690,695,700,704,709,714,719,723,728,733,738,743,748],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-european-research-council-award-692952","European Research Council","ERC Proof of Concept","Functional Optoacoustic Neuro-Tomography",null,"HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","DE",2016,"€150,000","The currently available neuroimaging tools, such as functional magnetic resonance imaging (fMRI) and optical microscopy, are not adequate for deep tissue volumetric visualization of brain activity in real time. The need for such solutions underlies the large scale multi-year European Human Brain Project as well as the BRAIN initiative promoted by the US government. Under the currently funded ERC-StG project, we have pioneered the so-called five-dimensional optoacoustic imaging method that can si",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-european-research-council-award-713709","SAMSON: Integrating computational nanoscience","INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE","FR","€149,750","Computer-aided design of macrosystems has greatly contributed to reduce production costs of cars, planes, etc., by replacing drawing boards and physical mock-ups with virtual modeling and simulation tools. Similarly, computational nanoscience is expected to have an increasingly essential impact on biology, chemistry, physics, material science, electronics, etc., by complementing experiments to reduce research and development cycles, lower costs, increase quality, etc.Unfortunately, while numerou",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":19,"country":20,"year":13,"amount":26,"abstract":27},"cordis-european-research-council-award-713626","Statistical modeling for Optimization Mobility","€149,109","This project will commercialize software and internet services for improving mobility-related online services such a ride sharing, navigation systems and crowdsourcing.  In particular, we will commercialize an app for mobile devices which makes predictions on the future travel intentions of the user based on the rich data available on the device through the use of highly efficient predictive modeling techniques.    Based on these predictions, the mobile device can communicate in the background o",{"id":29,"funder":7,"programme":8,"title":30,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":31},"cordis-european-research-council-award-713613","IceXL: Advanced modeling and slicing software for additive manufacturing","The ICEXL proof of concept project targets the pre-commercialization of a novel software for additive manufacturing of complex technical parts. It relies on innovative approaches from the SHAPEFORGE project (Stg-2012-307877) and in particular our software prototype IceSL. We aim at unlocking the full potential of additive manufacturing in terms of the complexity of the parts that can be designed and manufactured and in terms of customization possibilities by non-experts in computer aided design.",{"id":33,"funder":7,"programme":8,"title":34,"piName":10,"institution":35,"country":20,"year":13,"amount":36,"abstract":37},"cordis-european-research-council-award-713619","OCEAN in-situ Isotope and Dissolved gas sensing","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","€149,535","Through the 2012-2017 ERC Advanced Grant project ICE&LASERS, we have developed an innovative glacier probe, which includes an embedded laser spectrometer. It will drill down the Antarctic ice sheet in a single run, to measure in situ and real-time the depth profile of water isotopes and methane in trapped gases, with the aim to solve a major challenge in paleoclimate science. To test the performance of the laser spectrometer in a realistic and non-controlled environment, in 2014 it was deployed ",{"id":39,"funder":7,"programme":8,"title":40,"piName":10,"institution":41,"country":20,"year":13,"amount":42,"abstract":43},"cordis-european-research-council-award-692924","BioActive Coatings in multi-well cell culture plates","INSTITUT POLYTECHNIQUE DE GRENOBLE","€149,998","Cell culture is a method used for growing living cells artificially outside their natural environment under controlled conditions. It is used for a large range of applications such as studies of cellular functions, drug discovery, biotechnologies and regenerative medicine. Cell culture in vitro is generally performed on plastic substrates, especially multi-well plates or Petri dishes that are made of polystyrene, a very stiff and synthetic material. This stiff substrate can bias the experimental",{"id":45,"funder":7,"programme":8,"title":46,"piName":10,"institution":47,"country":48,"year":13,"amount":14,"abstract":49},"cordis-european-research-council-award-713651","Probing Complex Dynamical Structures in Three Dimensions","CONSIGLIO NAZIONALE DELLE RICERCHE","IT","Despite the recent expansion and enormous potential of three dimensional (3D) microscopy and 3D scanning, these technologies currently suffer from two limitations: i) lack of unity: although both technologies aim to unveil the 3D features of a system, they are being developed completely independently, resulting in lower flexibility and higher costs; ii) lack of dynamics: today these technologies can barely be applied to fast moving systems; however, crucial microscopic traits are dynamical, and ",{"id":51,"funder":7,"programme":8,"title":52,"piName":10,"institution":53,"country":54,"year":13,"amount":14,"abstract":55},"cordis-european-research-council-award-713422","Simultaneous Vision Simulator for optimizing selection of presbyopic correcions","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","ES","The lost of the eye’s capability to accommodate near and far objects (known as presbyopia) affects 100% of the population >45, i.e. 200 million in Europe and 1.200 million worldwide. Multifocal corrections, in the form of contact lenses (CLs), intraocular lenses (IOLs) or corneal surgery are increasingly used solutions to restore vision functionality in presbyopes. These corrections are based on the simultaneous vision principle, where a focused image and a defocused image are simultaneously pro",{"id":57,"funder":7,"programme":8,"title":58,"piName":10,"institution":59,"country":48,"year":13,"amount":14,"abstract":60},"cordis-european-research-council-award-693604","3D-Integrated single photon detector","UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA","Photonics, in recognition of its strategic significance and pervasiveness throughout many industrial sectors, has been identified as one of the Key Enabling Technologies for Europe. Photonics in combination with quantum information science has great potential to facilitate, transform and innovate future technologies for the better. The Proof of Concept (PoC) project intends to contribute to this by developing and testing a communication platform prototype, comprised of single photon detectors, w",{"id":62,"funder":7,"programme":8,"title":63,"piName":10,"institution":64,"country":65,"year":13,"amount":14,"abstract":66},"cordis-european-research-council-award-680559","Cost efficient thermal management in motors using next generation nanomaterials","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD","UK","Electric motor drives are the universal work horses of industry driving fans, pumps, power tools, compressors and materials handling\u002Fconveyor systems. More energy efficient motor designs are needed to meet increasingly stringent EU efficiency standards.  Better thermal management of electric motors could make this achievable.  Current technologies rely on expensive copper casings or inefficient air cooling.  Adding more copper is not feasible (bigger, heavier and expensive) and liquid cooling is",{"id":68,"funder":7,"programme":8,"title":69,"piName":10,"institution":64,"country":65,"year":13,"amount":70,"abstract":71},"cordis-european-research-council-award-693144","Perovskite Light Emitters","€149,983","Metal halide perovskites have recently astonished the research community and garnered a mass following to realize extremely high efficiency low cost photovoltaics. This work was largely catalyzed by outputs from the ERC-Stg HYPER, but in addition to solar cell applications, these materials could also be near perfect light emission materials for displays and lighting. This POC grant will formulate a strategy to move the perovskite materials and device research towards commercial exploitation as l",{"id":73,"funder":7,"programme":8,"title":74,"piName":10,"institution":75,"country":54,"year":13,"amount":21,"abstract":76},"cordis-european-research-council-award-727255","Emulating visual perception of contrast for image capture, post-production and synthesis","UNIVERSIDAD POMPEU FABRA","A significant research outcome from the IP4EC ERC Starting Grant has been to propose a vision model for contrast perception that can be realized as an image-dependent non-linear transformation that can accurately reproduce the detail and contrast directly visible in a scene. The model is based on findings from psychophysical and neurophysiological studies and is well suited to the statistics of natural images. The resulting transform is automatic (no need for user-selected parameters) and of ext",{"id":78,"funder":7,"programme":8,"title":79,"piName":10,"institution":80,"country":81,"year":13,"amount":10,"abstract":82},"cordis-european-research-council-award-713474","THOR – Total solution for High throughput surface enhanced Raman spectroscopy","DANMARKS TEKNISKE UNIVERSITET","DK","The aim of the PoC project is to develop a portable, low-cost device for highly sensitive and fast identification of molecules. For demonstration of the capability of the device we will focus on (i) toxic compounds in food and home environment, and (ii) compounds that are important for the cosmetics research industry. These applications all have the need of sample pretreatment, scalability, sensitivity, speed and ease of use that the device will offer. In addition, detection of both compound cla",{"id":84,"funder":7,"programme":8,"title":85,"piName":10,"institution":86,"country":87,"year":13,"amount":10,"abstract":88},"cordis-european-research-council-award-727674","Immunological Diagnosis of Familial Mediterranean Fever","VIB VZW","BE","Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease worldwide. The disease is highly prevalent in countries of the Mediterranean basin, the Caucasus and the Middle East, with 1:1000 up to 1:500 inhabitants being affected in countries like Turkey and Armenia. FMF has further spread to other regions of the world with migrations of these populations in modern history and today. Colchicine therapy is the gold standard for FMF patients, but given the risks involve",{"id":90,"funder":7,"programme":8,"title":91,"piName":10,"institution":92,"country":93,"year":13,"amount":14,"abstract":94},"cordis-european-research-council-award-713533","sImultaNeous oxIdaTIon of Ammonium and meThane at lOw tempeRatures (INITIATOR)","STICHTING RADBOUD UNIVERSITEIT","NL","Simultaneous ammonium and methane oxidation coupled to nitrogen removal provides a great opportunity for sustainable and economical feasible wastewater treatment solutions. The key processes performed are anaerobic ammonium oxidation (anammox) and nitrate-dependent anaerobic oxidation of methane. Combining these two processes results in a system that simultaneously removes ammonium, nitrate (via nitrite), and methane without the need for extra aeration and the addition of electron donors. Such a",{"id":96,"funder":7,"programme":8,"title":97,"piName":10,"institution":98,"country":99,"year":13,"amount":14,"abstract":100},"cordis-european-research-council-award-704340","Ribo-regulators that sense trace antibiotics","WEIZMANN INSTITUTE OF SCIENCE","IL","Over-usage of antibiotics in the clinic and in agriculture resulted not only in increased drug resistance among pathogenic bacteria, but also in the spread of antibiotics metabolites in the environment and in our food. This poses multiple significant threats, including the development and expansion of multi-drug resistant pathogens. The health and safety risks imposed by the presence of antibiotics in food, drinking water, and environmental waters raise the strong necessity for continuous monito",{"id":102,"funder":7,"programme":8,"title":103,"piName":10,"institution":104,"country":105,"year":13,"amount":106,"abstract":107},"cordis-european-research-council-award-713445","BIONOTE– A CROWDSCIENCE PLATFORM FOR IDENTIFYING AND LEARNING ABOUT ALL SPECIES ON EARTH","GOETEBORGS UNIVERSITET","SE","€149,427","BIONOTE– A CROWDSCIENCE PLATFORM FOR IDENTIFYING AND LEARNING ABOUT ALL SPECIES ON EARTHMAJOR GOAL: To inspire and empower people to identify, document, explore and protect the world’s biodiversity. BioNote will advance Europe’s commitment to monitor and protect biodiversity, by greatly facilitating access to species identifications worldwide. It will simultaneously increase information on where species occur for research, education, citizens, government and industry. We share this planet with 7",{"id":109,"funder":7,"programme":8,"title":110,"piName":10,"institution":111,"country":12,"year":13,"amount":14,"abstract":112},"cordis-european-research-council-award-665672","Multi-revolution non-volatile magnetic sensors","JOHANNES GUTENBERG-UNIVERSITAT MAINZ","Multi-revolution sensors that detect multiple rotations are being used in many areas of the automotive and automation industry. The current generation of discrete multi-revolution sensors has major drawbacks, such as complex architecture, limited applicability and high cost. MultiRev will demonstrate the proof-of-concept of a novel monobloc multi-revolution sensor based on non-volatile low power domain wall motion induced by the rotating fields that are being sensed to count revolutions. A large",{"id":114,"funder":7,"programme":8,"title":115,"piName":10,"institution":116,"country":117,"year":13,"amount":118,"abstract":119},"cordis-european-research-council-award-713689","Laser-Based Bioprinter","TECHNISCHE UNIVERSITAET WIEN","AT","€149,850","Bioprinting is a rapidly developing technology sector aimed at additive manufacturing of tissues and organs. It is expected to lead to the most disruptive biomedical applications of additive manufacturing. Apart from tissue engineering and regenerative medicine, bioprinting applications of immediate commercial and societal benefit include the development of personalized cancer therapies and realization of in vitro tissue models based on human biology for reliable drug tests in pharma industry. T",{"id":121,"funder":7,"programme":8,"title":122,"piName":10,"institution":123,"country":117,"year":13,"amount":14,"abstract":124},"cordis-european-research-council-award-713713","A Compact Terahertz Trace Gas Detector","UNIVERSITAET INNSBRUCK","A near-spherical terahertz resonator will be constructed and integrated into a mobile terahertz trace gas detector. It will deliver about two orders of magnitude larger terahertz path lengths, corresponding to trace gas detection sensitivity down to one part per million. With this a means becomes available to measure trace gases that are very difficult to monitor by standard means, such as the atmospherically important hydroxyl radical.",{"id":126,"funder":7,"programme":8,"title":127,"piName":10,"institution":128,"country":65,"year":13,"amount":129,"abstract":130},"cordis-european-research-council-award-692694","The development, evaluation and commercialisation of an early years test of colour vision deficiency.","THE UNIVERSITY OF SUSSEX","€149,645","Colour vision deficiency (CVD) is a genetic disorder of colour vision that affects 7.4% of European males and 0.4% of European females. Although there are reliable tests for diagnosing CVD in adults and older children, there are only a few tests for young children, and fundamental issues with these tests render them unreliable. For example, colours used in the tests are too similar for young children to discriminate given their immature colour vision, tasks are too difficult for them to complete",{"id":132,"funder":7,"programme":8,"title":133,"piName":10,"institution":134,"country":87,"year":13,"amount":135,"abstract":136},"cordis-european-research-council-award-713726","MUTATION++ library, technology transfer from atmospheric entry plasmas to biomass pyrolysis","VON KARMAN INSTITUTE FOR FLUID DYNAMICS","€149,921","One successful outcome of the AEROSPACEPHYS ERC StG, entitled “Multiphysics models and simulations for reacting and plasma flows applied to the space exploration program,” is the development of a new software library called MUTATION++: MUlticomponent Thermodynamic And Transport properties for IONized gases in C++. The library compiles the state-of-the-art physico-chemical models and algorithms developed by the team into a highly extensible and robust software package to be coupled to simulation ",{"id":138,"funder":7,"programme":8,"title":139,"piName":10,"institution":140,"country":48,"year":13,"amount":141,"abstract":142},"cordis-european-research-council-award-713652","Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder","UNIVERSITA DEGLI STUDI DI MILANO","€145,250","Duplication of chromosome region 7q11.23 (7Dup), comprising 26-28 genes, is one of best characterized copy number variations (CNV) causing Autism Spectrum Disorder (ASD), a very prevalent neurodevelopmental condition affecting more than 1% individuals worldwide, and for which no effective treatment is available. Despite the remarkable consistency of core ASD symptoms (impairment in language and sociability along with stereotyped behaviours), over 400 causative genetic lesions have been thus far ",{"id":144,"funder":7,"programme":8,"title":145,"piName":10,"institution":116,"country":117,"year":13,"amount":146,"abstract":147},"cordis-european-research-council-award-692653","Non-Volatile Magnetic Flip Flop","€149,625","The physical limits of CMOS scaling and the prohibitively high costs of future technology nodes, allows to foresee the endof further progress of CMOS technology in the near future and emphasizes the dire need to explore alternativetechnologies and computational principles.Spin as an alternative degree of freedom for computation and information storage attracts much attention due to its nonvolatility, high endurance, fast operation, and CMOS compatibility. Even though first promising results are ",{"id":149,"funder":7,"programme":8,"title":150,"piName":10,"institution":151,"country":152,"year":13,"amount":14,"abstract":153},"cordis-european-research-council-award-712738","Novel Thermoelectric Energy Solutions based on Flexible Thin-Film Materials","AALTO KORKEAKOULUSAATIO SR","FI","In this Proof-of-Concept project we will create a completely new kind of integrated energy solution platform based on thermoelectric (TE) heat energy harvesting materials that are capable of converting various types of heat flows directly into electricity. The strong basis for the project is the new oxide-based thermoelectric inorganic-organic hybrid materials discovered in the PI's ERC Advanced Grant Project “Molecular-Layer-Engineered Inorganic-Organic Hybrid Materials (LAYERENG-HYBMAT)”. Thes",{"id":155,"funder":7,"programme":8,"title":156,"piName":10,"institution":157,"country":54,"year":13,"amount":158,"abstract":159},"cordis-european-research-council-award-709590","Copper Catalysis Applications","UNIVERSITAT DE GIRONA","€147,500","An innovative methodology has been developed in the field of copper-catalyzed cross coupling catalysis, with the goal of developing more efficient and sustainable synthetic protocols used by Chemical and Pharmaceutical Industries.Successful research developed within the ERC-2011-StG-277801 project has led to discover new methodologies for sustainable catalytic transformations using copper catalysts to form C-C or C-heteroatom bonds, finding out the feasibility of uncommon copper(III) species as ",{"id":161,"funder":7,"programme":8,"title":162,"piName":10,"institution":163,"country":65,"year":13,"amount":164,"abstract":165},"cordis-european-research-council-award-727738","Monolithic Diamond Raman Laser (MonoDial)","UNIVERSITY OF STRATHCLYDE","€149,962","This proof of concept proposal will build on an innovative monolithic diamond Raman laser, with near quantum limitedefficiency demonstrated during the ERC starting grant DiaL. A range of important applications will be scoped and the technology tailored to meet the most promising market demands. The result will be a platform approach to compact laser design taking existing Nd:YAG-based lasers to wavelengths with a strong applications pull that cannot be met with current technology. This will exte",{"id":167,"funder":7,"programme":8,"title":168,"piName":10,"institution":169,"country":93,"year":13,"amount":21,"abstract":170},"cordis-european-research-council-award-712951","A treatment for BRAF inhibitor resistant melanoma","STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS","Some 50% of human melanoma tumors have activating mutations in the BRAF gene. BRAF inhibitor drugs given either alone or in combination with MEK inhibitors have improved progression-free and overall survival in patients with BRAF mutant metastatic melanoma. However, drug resistance invariably limits the duration of clinical benefit of such treatments and is almost always associated with re-activation of signaling through the MAP kinase pathway in the presence of drug due to secondary mutations i",{"id":172,"funder":7,"programme":8,"title":173,"piName":10,"institution":174,"country":93,"year":13,"amount":14,"abstract":175},"cordis-european-research-council-award-713537","Commercialising MR-HIFU: an Image-Guided Local Drug-Delivery Platform","UNIVERSITAIR MEDISCH CENTRUM UTRECHT","Reducing the high attrition rates in drug development continues to be a key challenge for the pharmaceutical industry. With average drug development costs of over $2 billion dollar and a 95% failure rate of cancer drugs in Phase I trials, a new paradigm is highly needed.iGOLDD represents a unique opportunity for the commercialisation of a powerful alternative drug-delivery solution that has the potential to locally boost the efficacy of many drugs for a range of clinical indications. Prof. Moone",{"id":177,"funder":7,"programme":8,"title":178,"piName":10,"institution":179,"country":48,"year":13,"amount":14,"abstract":180},"cordis-european-research-council-award-693606","Immunomodulatory effects of sustained pantethine release in inflammatory diseases","UNIVERSITA DEGLI STUDI DI VERONA","Auto-immune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) and inflammation-associated brain diseases including Alzheimer's disease (AD) globally make up a €45B market and cost society close to €648B. The huge number of patients with these diseases causes an enormous socioeconomic burden. Currently, MS, AD and RA affect 120M people worldwide. There is no cure for AD and treatments for autoimmune diseases are not fully effective and reducing the inflammatory component in t",{"id":182,"funder":7,"programme":8,"title":183,"piName":10,"institution":184,"country":54,"year":13,"amount":10,"abstract":185},"cordis-european-research-council-award-713503","Coordinated Development of Inhibitors and Biomarkers for Resistance to Antiangiogenics in Cancer - AngioResist","INSTITUT CATALA D'ONCOLOGIA","Many anti-angiogenic drugs are clinically used in several types of cancer to block angiogenesis, impair tumor growth, progression and dissemination. Nevertheless, clinical trials report emergence of resistance to treatment and a failure in long-lasting effects of these therapies. To date, resistant patients do not currently have any established, proven alternative therapeutic possibility and the medical field is moving towards a careful selection of subgroups or subtypes of patients that have to",{"id":187,"funder":7,"programme":8,"title":188,"piName":10,"institution":189,"country":65,"year":13,"amount":190,"abstract":191},"cordis-european-research-council-award-693739","Multi-tubular Catalytic Reactor for Flexible Production of Fine Chemicals","UNIVERSITY OF WARWICK","€149,930","Small scale continuous synthesis in catalytic flow reactors is recognized as one of the major technologies that would enable and even boost process intensification and it would allow to develop substantially cleaner, safer and more energy efficient chemical processes. The leading fine chemicals companies are already implementing restructuring programs targeted at the reduction of large scale chemical manufacturing and eliminations of large chemical plants. The scalability of the catalytic flow r",{"id":193,"funder":7,"programme":8,"title":194,"piName":10,"institution":195,"country":196,"year":13,"amount":197,"abstract":198},"cordis-european-research-council-award-693433","A lab-on-chip platform for blood cell counting and identification at the point-of-care","NATIONAL CENTER FOR SCIENTIFIC RESEARCH DEMOKRITOS\"","EL","€148,250","Blood cell counting\u002Fidentification is the most powerful and widespread approach throughout the world for assessing an individual’s health status. The diagnosis and monitoring of an infection (e.g. HIV, malaria, bacterial infection), the monitor of a chemotherapy outcome (e.g. in cancer patients) or even the diagnosis of rare diseases (e.g. sickle cell disease, non-Hodgkin lymphomas), relies on analysing the number and\u002For the morphology of different types of blood cells.  Here, we aim to validate",{"id":200,"funder":7,"programme":8,"title":201,"piName":10,"institution":202,"country":87,"year":13,"amount":203,"abstract":204},"cordis-european-research-council-award-713547","Study of the therapeutic potential of an Akkermansia muciniphila-based products in subjects with an increased cardio-metabolic risk.","UNIVERSITE CATHOLIQUE DE LOUVAIN","€149,375","Overweight and obesity have reached worldwide epidemic level. Both overweight and obesity are characterized by comorbidities such as cardio-metabolic risk factors (i.e., insulin resistance, type 2 diabetes, hypertension, dyslipidemia, low-grade inflammation) representing a major public health problem. Therefore, it is urgent to find a therapeutic solution to target all these metabolic disorders.Among the environmental factors able to influence the individual susceptibility to gain weight and to ",{"id":206,"funder":7,"programme":8,"title":207,"piName":10,"institution":208,"country":65,"year":13,"amount":209,"abstract":210},"cordis-european-research-council-award-713368","Enhancing OLED device performance using Fused Borylated Materials","THE UNIVERSITY OF MANCHESTER","€149,662","Organic Light Emitting Diodes (OLEDs) are attractive for use in high efficiency illumination and flexible displays. The current state of the art OLED materials use Ir or Pt based phosphorescent materials, which whilst achieving impressive efficiencies have significant cost, and supply issues associated with rare precious metals. Metal free OLEDs are preferable based on low relative cost and ease of fabrication but to date have not been competitive with Ir \u002F Pt based OLEDs. This is because metal ",{"id":212,"funder":7,"programme":8,"title":213,"piName":10,"institution":214,"country":65,"year":13,"amount":215,"abstract":216},"cordis-european-research-council-award-676835","Discovery and commercialisation of novel compounds targeting redox proteins","THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE","€149,996","The Peroxiredoxin proteins represent a currently untapped molecular therapeutic target. We recently characterised a rangeof novel chemical compounds that could alter the function of one of the peroxiredoxin family members, peroxiredoxin 4(PRDX4). The approach involved high-throughput computational “virtual” compound screening involving our supercomputerfacility at the University of Cambridge. Given our success in finding chemicals that could affect the function of theseproteins, we would now lik",{"id":218,"funder":7,"programme":8,"title":219,"piName":10,"institution":92,"country":93,"year":13,"amount":14,"abstract":220},"cordis-european-research-council-award-713524","CONQUEST: Enabling advanced medical imaging","CONQUEST: Enabling advanced medical imagingCONQUEST is formed around a new imaging technology platform. The basis is the newly developed nanoparticles function as contrast agents for a variety of imaging modalities that are presently used in healthcare such as ultrasound and MRI. In particular, the nanoparticles are a completely novel type of contrast agent for ultrasound imaging. The high stability and long shelf life of the particles combined with visibility in ultrasound could allow applicati",{"id":222,"funder":7,"programme":8,"title":223,"piName":10,"institution":224,"country":65,"year":13,"amount":225,"abstract":226},"cordis-european-research-council-award-727440","Biodiversity Change: an open access data resource supporting societal responses to the biodiversity crisis","THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS","€149,428","Biodiversity CHANGE is a major, but still underappreciated, threat to humanity. It arises when there is unprecedented turnover in the identities of species that comprise ecological assemblages. To understand, monitor and ameliorate this CHANGE, and to enable appropriate societal responses, policy makers and conservation managers urgently need access to the best possible data. At present the ability of practitioners to elucidate ecosystem responses to anthropogenic impacts is hampered by data ava",{"id":228,"funder":7,"programme":8,"title":229,"piName":10,"institution":230,"country":12,"year":13,"amount":14,"abstract":231},"cordis-european-research-council-award-693361","UPscaling GRaphite Electrochemical ExfoliatioN","TECHNISCHE UNIVERSITAET DRESDEN","The possible utilization of graphene as key component in composites, energy storage and conversion devices is heavily hampered by the limited availability of high-quality graphene materials. The current graphene production methods, such as mechanical exfoliation, chemical vapor deposition and chemical oxidation and exfoliation, suffer from extremely low yield of product, limited scalability or a strong chemical oxidation by which a significant number of defects are irreversibly introduced to the",{"id":233,"funder":7,"programme":8,"title":234,"piName":10,"institution":235,"country":54,"year":13,"amount":236,"abstract":237},"cordis-european-research-council-award-713682","Ensured Randomness Integrity in Device-Independent Networks","FUNDACIO INSTITUT DE CIENCIES FOTONIQUES","€149,925","ERIDIAN will develop a market-ready quantum random number generator for Device Independent (DI) Quantum Cryptography (QKD), which offers the best possible security guarantees.  The prototype developed in ERIDIAN will enable major industrial players to make DI QKD a commercial reality.  Current, classical cryptography is based on the assumed difficulty of certain mathematical problems and thus insecure against future mathematical advances and against quantum computers.  Quantum cryptography gives",{"id":239,"funder":7,"programme":8,"title":240,"piName":10,"institution":98,"country":99,"year":13,"amount":14,"abstract":241},"cordis-european-research-council-award-692448","Chiral based spin organic light emitting diodes","Organic Light-Emitting Diode (OLED) is an attractive solution for displays and lighting due to its low cost of production. The adoption of OLED technology in televisions, smartphones, and increasing number of applications in wearables, transportation and lighting are contributing to the growth of this market. OLED technology offers sharper images, better contrast and crisp colours than any existing display technology.In lighting applications the efficiency of serial production OLEDs cannot curre",{"id":243,"funder":7,"programme":8,"title":244,"piName":10,"institution":92,"country":93,"year":13,"amount":14,"abstract":245},"cordis-european-research-council-award-727666","HYPERTRANS: Transport of hyperpolarized substrates for metabolic MR imaging","Dynamic metabolic imaging with hyperpolarized substrates is a new and unique non-invasive magnetic resonance imaging tool. It opens the window to metabolic aberrations at the heart of many diseases, and the ability to image these changes provides the opportunity to fundamentally improve clinical diagnosis and treatment follow-up. Our long-term ambition is to make hyperpolarized substrates for metabolic imaging with MRI available for every clinical institution. The short-term goal to be reached f",{"id":247,"funder":7,"programme":8,"title":248,"piName":10,"institution":249,"country":12,"year":13,"amount":250,"abstract":251},"cordis-european-research-council-award-680882","Companion Nanodiagnostics for Quantifying EPR and Stratifying Patients to Targeted Nanotherapies","UNIVERSITAETSKLINIKUM AACHEN","€145,312","CONQUEST aims to commercialise a first-of-its-kind platform technology for imaging a biological effect – i.e. the EPR effect – that is predictive for a cancer patient's response to tumor-targeted nanomedicine (NM) therapy. CONQUEST thereby addresses a key issue in the (nano)pharmaceutical industry; as currently large proportions of cancer patients do not respond to NM, while others show major improvements in terms of response rates, survival times and quality of life. This trend impairs the outc",{"id":253,"funder":7,"programme":8,"title":254,"piName":10,"institution":255,"country":93,"year":13,"amount":14,"abstract":256},"cordis-european-research-council-award-713727","GlioDx - Blood platelet-based monitoring and treatment optimisation for glioblastoma patients","STICHTING AMSTERDAM UMC","Glioblastoma (GBM) is a devastating primary brain cancer which affects about 230.000 people annually. The choice for treatment depends on the subtype of GBM. An accurate detection of tumour subtype is therefore essential for a personalised targeted treatment. Diagnosis, classification and treatment monitoring occurs currently by radiology and repeated invasive biopsies. There is a need for non-invasive, actionable biomarkers for early-stage diagnosis and disease monitoring.During our ERC researc",{"id":258,"funder":7,"programme":8,"title":259,"piName":10,"institution":189,"country":65,"year":13,"amount":42,"abstract":260},"cordis-european-research-council-award-693243","Rapid Defect Characterisation by Non-Contact Ultrasonic Scanning","Surface defect detection and characterization is a safety-critical non-destructive testing (NDT) process for many regulated industries, including railway networks, oil and gas, energy generation, aerospace, automotive, and civil infrastructure. The cost of repairing and replacing defective or old components can be extremely high, both in terms of the costs of the components and the related economical costs of a system shut-down. There are several NDT approaches in common use, but these have a nu",{"id":262,"funder":7,"programme":8,"title":263,"piName":10,"institution":235,"country":54,"year":13,"amount":14,"abstract":264},"cordis-european-research-council-award-713659","Hybrid quantum dot and graphene wearable sensor for systemic hemodynamics and hydration monitoring","The main goal of GRAPHEALTH is to exploit the inherent properties of hybrid graphene – quantum dot detectors in order to enable constant non-invasive health monitoring through vital parameters. Unlike current bulky systems, our approach enables a flexible, compact and wearable health monitoring system for constant monitoring for consumer health applications and muscle health of athletes during exercise or after injury.The hybrid quantum dot and graphene technology exhibits very high sensitivity ",{"id":266,"funder":7,"programme":8,"title":267,"piName":10,"institution":268,"country":54,"year":13,"amount":269,"abstract":270},"cordis-european-research-council-award-713677","Catalytic reductive carboxylation of unactivated olefins with carbon dioxide","FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA","€149,500","Carboxylic acids are building blocks of utmost importance in our chemical industry, as these motifs are extensively used in the manufacture of soaps, detergents, pharmaceuticals, rubber, plastics, dyes, textile, perfumes, and animal feed, among many others. Current industrial protocols for their synthesis rely heavily on toxic reagents, lengthy-step pathways or waste-producing procedures such as hydrolysis of nitriles or two-step techniques based on hydroformylation of olefins with highly toxic ",{"id":272,"funder":7,"programme":8,"title":273,"piName":10,"institution":151,"country":152,"year":13,"amount":274,"abstract":275},"cordis-european-research-council-award-727305","Self-calibrating nanobolometer based on superconductor–normal-metal hybrids","€149,838","In this project, we develop a microwave nanobolometer invented in the ERC Starting Grant ”Single-Photon Microwave Devices: era of quantum optics outside cavities (SINGLEOUT)” into a proof of concept and carry out a market analysis and partnering with the relevant industrial players in the field.For a successful proof of concept, a self-calibrating function will be implemented into the nanobolometer, providing us with an extremely sensitive and easy-to-use detector for microwave radiation. The ne",{"id":277,"funder":7,"programme":8,"title":278,"piName":10,"institution":230,"country":12,"year":13,"amount":279,"abstract":280},"cordis-european-research-council-award-727651","Commercializing NuDev's Organic Permeable Base Transistors (OPBT) in full Organic photodetectors and chip-size spectrometers","€149,687","Within the ERC Advanced Researcher Grant “NuDev”, promising organic electronic devices especially transistors have been developed. A candidate being able to replace inorganic transistors due its outstanding features and potential low cost production process is the Organic Permeable Base Transistor (OBPT). However, electronic industry is almost completely silicon based today. Therefore, applications using organic electronic devices need to compete on the basis of superior and unique features to o",{"id":282,"funder":7,"programme":8,"title":283,"piName":10,"institution":284,"country":12,"year":13,"amount":14,"abstract":285},"cordis-european-research-council-award-727417","dIagnoSIs app for regular aTrial arrhytmia like Flutter","MATHE MEDICAL GMBH","We have been developing a new diagnosis tool for cardiac arrhythmia. Our clients are expert cardiologists. They can use our Mobile App with a Smartphone or Tablet, easily and cost-efficiently. The App records the beeps of a heart rate monitor or takes a picture of the printout of an electrocardiogram (ECG), communicates with a server, and displays the result of the calculations as decision support for the medical expert.Depending on the diagnosis of the medical expert either a long-term treatmen",{"id":287,"funder":7,"programme":8,"title":288,"piName":10,"institution":289,"country":48,"year":13,"amount":14,"abstract":290},"cordis-european-research-council-award-693680","MobIle health-Care system for monitoring toxicity and symptoms in cAncer patients Receiving diseasE-oriented therapy","SMARTLY: NATIVES OF SMART LIVING SRL","The project aims at developing a pre-commercial solution, till preparing its entrance to the market, of a new cost-effective mobile system for technology-aided home treatment with oral drugs in cancer patients. This project stems from the ERC Starting Grant VISION, which demonstrated the effectiveness of model-driven approaches for adaptive context-aware resource configuration in internetworking smart objects and wireless multimedia sensor networks. Pervasiveness and easiness of usage that inter",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":294,"country":54,"year":13,"amount":295,"abstract":296},"cordis-european-research-council-award-713641","Early Stage Sensing of Fouling in Membrane Water Treatment","UNIVERSIDAD DEL PAIS VASCO\u002F EUSKAL HERRIKO UNIBERTSITATEA","€149,760","UN-Water has recently warned that in only ten years' time, by 2025, water scarcity will be affecting 1.8 billion people, with two-thirds of the world population possibly living under conditions of water stress. There exists, hence, a strong need to rigorously manage drinking water resources. The production of potable water by membrane water treatment systems is relatively economic and benign. 80 million m3 of potable water are already produced nowadays using membranes. However, the efficiency of",{"id":298,"funder":7,"programme":8,"title":299,"piName":10,"institution":300,"country":117,"year":13,"amount":301,"abstract":302},"cordis-european-research-council-award-727416","Chemical Hematology: breaking resistance of hematological malignancies through personalized drug trials","CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH","€146,668","Personalized medicine aspires to provide optimal therapy in real-time during patient treatment, however current methodology falls short to deliver this in a robust manner. With this in mind, we invented a method for the screening of thousands of drug responses in small samples of an individual’s peripheral blood by automated microscopy and single-cell image analysis. We termed this method pharmacoscopy. In the course of carrying out the i-FIVE ERC grant project plan, we began screening for novel",{"id":304,"funder":7,"programme":8,"title":305,"piName":10,"institution":306,"country":65,"year":13,"amount":307,"abstract":308},"cordis-european-research-council-award-713410","Commercialisation of new miniaturised, automated robots for high throughput training and assessment of dexterity in rats and mice.","KING'S COLLEGE LONDON","€149,761","The invention: We have developed new, cost-effective miniature robots using 3D printers and customised electronics and software. Large numbers of robots can run in parallel unattended for 24 hours a day, 7 days a week. These robots can be adapted for a variety of applications in industry and research. In this Proof of Concept phase we will begin commercialisation of one of our robots.Commercial potential: We will refine our robots to accelerate a rate-limiting step in the drug discovery pipeline",{"id":310,"funder":7,"programme":8,"title":311,"piName":10,"institution":312,"country":65,"year":13,"amount":313,"abstract":314},"cordis-european-research-council-award-693227","Translational synergistic growth factor microenvironments for bone regeneration","UNIVERSITY OF GLASGOW","€148,783","We propose a robust polymer-based system that allows a safer delivery of recombinant human bone morphogenetic protein-2 (rhBMP2) for bone tissue engineering. We have teamed up with a surgeon (Dr. Meek) and an SME (Taragenyx Ltd.) in the planning stages, for the appraisal of the proposal from a translational standpoint. Later, Taragenyx will also be involved with scaling-up and commercialisation. We filed a patent covering the technology, and licensed Taragenyx its exploitation. rhBMP2 is a power",{"id":316,"funder":7,"programme":8,"title":317,"piName":10,"institution":318,"country":12,"year":13,"amount":319,"abstract":320},"cordis-european-research-council-award-693521","Commercialization of an innovative tomographic reconstruction algorithm (Super-sampling SART) for various geometry setups","JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN","€148,750","In this proposal, we would like to advance our high quality and highly flexible multi-purpose three-dimensional tomographic reconstruction algorithm from a state of the art research tool to an innovative commercial software product. Transmission tomography uses N-1 dimensional images to reconstruct an N-dimensional object. It is applicable on a multitude of applications ranging from scientific to industrial level. Our implementation has already proven its superior image reconstruction capabiliti",{"id":322,"funder":7,"programme":8,"title":323,"piName":10,"institution":324,"country":325,"year":13,"amount":326,"abstract":327},"cordis-european-research-council-award-713671","Asset Centric Adaptive Protection","UNIVERSITY OF LIMERICK","IE","€149,977","The proliferation of mobile and ubiquitous computing technology is radically changing the ways in which we live our lives: from interacting with friends & family, to how we produce & consume services and engage in business. However, this pervasiveness of technologies, and their increasingly seamless integration and inter-operation, are blurring the boundaries  between systems. This poses significant challenges for security engineers who aim to design systems that monitor and control the movement",{"id":329,"funder":7,"programme":8,"title":330,"piName":10,"institution":92,"country":93,"year":13,"amount":14,"abstract":331},"cordis-european-research-council-award-693064","Precision tracking with tools from Astrophysics","In our ERC-funded project we have used interferometric techniques from radio astronomy to precisely localize bunches of cosmic ray particles rushing through our Earth atmosphere at light speed. Here we want to use this technique to provide precise and robust tracking of tracking of vehicles, such as robotic lawnmowers, ships and planes. Localizing vehicles as precisely as possible has become an ever more important aspect of modern day life, as is evident from the success of GPS. However, under c",{"id":333,"funder":7,"programme":8,"title":334,"piName":10,"institution":335,"country":54,"year":13,"amount":14,"abstract":336},"cordis-european-research-council-award-713251","Software tools for fast, reliable analysis of magnetic materials in the electron microscope","UNIVERSIDAD COMPLUTENSE DE MADRID","This proof-of-concept project aims at developing a software tool to be integrated in commercial electron microscope control platforms dedicated to the development of novel magnetic materials. Magnetic materials have applications in different areas such as data storage, sensors, biomedical applications or spintronic devices. Future technological developments will come hand-in-hand with new materials based on novel atomic arrangements, and electron microscopy is a unique technique to analyze natur",{"id":338,"funder":7,"programme":8,"title":339,"piName":10,"institution":340,"country":54,"year":13,"amount":341,"abstract":342},"cordis-european-research-council-award-713551","Developing an anti-Myc cell-penetrating peptide for cancer treatment","FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON (VHIO)","€147,750","Despite ever-increasing investments in the development of new treatments, many cancers remain incurable. One reason is that most current therapies target redundant functions around which tumour cells can build resistance. We focus instead on a unique and essential cellular function: the Myc oncogene, deregulated in more than 70% of human cancers. Targeting Myc has long been considered unfeasible because of potentially catastrophic side effects. Against this dogma, using a Myc inhibitor called Om",{"id":344,"funder":7,"programme":8,"title":345,"piName":10,"institution":346,"country":105,"year":13,"amount":14,"abstract":347},"cordis-european-research-council-award-680904","Geographic mapping of radio signals","CHALMERS TEKNISKA HOGSKOLA AB","MapCOM will transition the fundamental research carried out in the COOPNET project (the PI’s Starting Grant Project) to concrete applications related to power-efficient and scalable resource allocation for cellular networks, in particular for 5G communications. The key idea is to harness uncertain location information to build statistical radio maps, which can be used to predict radio signal quality and perform long-term proactive resource allocation. This will reduce operating costs for operato",{"id":349,"funder":7,"programme":8,"title":350,"piName":10,"institution":351,"country":352,"year":13,"amount":14,"abstract":353},"cordis-european-research-council-award-713736","Embedded Neuromorphic Sensory Processor","UNIVERSITAT ZURICH","CH","Neuromorphic computing has demonstrated high potential for creating computing systems with order-of-magnitude improvements in energy efficiency and robustness to noisy or unreliable sensory signals, such as those inherent in vision. However, a significant roadblock to realizing the full potential of this emerging brain-inspired technology is the current practical need to use inefficient and slow (high latency) legacy von Neumann architectures to convert the input data that needs to be processed,",{"id":355,"funder":7,"programme":8,"title":356,"piName":10,"institution":357,"country":20,"year":13,"amount":358,"abstract":359},"cordis-european-research-council-award-692765","A tactile prosthesis to improve speech perception in persons with hearing loss.","UNIVERSITE PARIS CITE","€149,950","The “FeelSpeech” project will provide proof of concept of a novel prosthesis that will allow people with hearing loss to better understand speech. The prosthesis will be worn on the wrist and will resemble a wristwatch. A special, novel kind of tactile stimulation called “microstroking” provided by the device will supplement what a person hears, and this information will be unconsciously made use of by the user’s brain, providing improved speech perception even when the user has almost lost all ",{"id":361,"funder":7,"programme":8,"title":362,"piName":10,"institution":363,"country":12,"year":13,"amount":14,"abstract":364},"cordis-european-research-council-award-693017","Surface modulation of wounds: heal by inhalants! Novel drug-based treatment for excessive scars and chronic wounds.","UNIVERSITAET BREMEN","The innovative concept of the ERC Starting Grant project “Keratinocytes and Matrix metalloproteinases: driving force of skin wound contraction?” was to use inhalants for skin wounds and it proved to be excellent and functional. Surface Modulation of Wounds (SUMOWO) with these anti-inflammatory, pro-migratory and anti-fibrotic compounds will be beneficial for chronic wound healing and reduce excessive scarring. This novel drug-based treatment strategy marks a novel era of wound care. A clinical p",{"id":366,"funder":7,"programme":8,"title":367,"piName":10,"institution":214,"country":65,"year":13,"amount":368,"abstract":369},"cordis-european-research-council-award-693056","Rituximab in Acute Myocardial Infarction","€149,402","Cardiovascular diseases (CVD) represent a major cause of morbidity and mortality. The best current therapy reduces CV risk by only 25-30% and remains ineffective in reducing the excess risk associated with several co-morbidities. Therefore, there is considerable need for new therapies to limit the burden of CVD. Based on a current ERC Starting Grant project, the applicant’s group proposed and validated the concept that mature B lymphocytes are instrumental in the orchestration of the inflammator",{"id":371,"funder":7,"programme":8,"title":372,"piName":10,"institution":373,"country":93,"year":13,"amount":14,"abstract":374},"cordis-european-research-council-award-713483","A new biosynthesis procedure for pharmaceutically active gamma-aminobutyric acids","RIJKSUNIVERSITEIT GRONINGEN","Chiral γ-aminobutyric acids (GABAs) represent abundantly prescribed drugs, which are broadly applied as anticonvulsants, antidepressants and for the treatment of neuropathic pain. With the incorporation of more population to western-based style in the coming decades, there is a need of developing and producing pharmaceutically active GABAs and similar (or generic) drugs for higher number of consumers. Supported by an ERC starting grant, Prof. Poelarends has developed an efficient, enzyme-based p",{"id":376,"funder":7,"programme":8,"title":377,"piName":10,"institution":378,"country":54,"year":13,"amount":14,"abstract":379},"cordis-european-research-council-award-713608","Active microcleaners for water remediation","FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA","We have witnessed a massive growth in industrial and agricultural activities, and a huge increment in the release of pollutants to our aqueous ecosystems. Centralized water suppliers look for systems energetically more viable than current ones and for onsite water purification systems which can be faster, more affordable and less aggressive. Here, we present a novel active self-mixing and multifunctional system (microcleaners) capable of cleaning chemical and biological pollutants. Using a combi",{"id":381,"funder":7,"programme":8,"title":382,"piName":10,"institution":383,"country":20,"year":13,"amount":14,"abstract":384},"cordis-european-research-council-award-727758","RNA virus attenuation by altering mutational robustness","INSTITUT PASTEUR","RNA viruses have extreme mutation frequencies. When a RNA virus replicates, nucleotide mutations are generated resulting in a population of variants. This genetic diversity creates a cloud of mutations that are potentially beneficial to viral survival, but the majority of mutations are detrimental to the virus. By increasing the mutation rate of a RNA virus, viral fitness is reduced because it generates more errors, and attenuates the virus during in vivo infection. Another feature that affects ",{"id":386,"funder":7,"programme":8,"title":387,"piName":10,"institution":388,"country":54,"year":13,"amount":21,"abstract":389},"cordis-european-research-council-award-713728","microRNA replacement therapy for mature B cell neoplasias","CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)","Mature B cell neoplasias include most of Non-Hodgkin Lymphomas (NHL), such as Diffuse Large B Cell Lymphomas and Burkitt Lymphoma and also B cell Chronic Lymphocytic Leukemia. It is estimated that about 60000-80000 new cases of mature B cell neoplasias are diagnosed every year in Europe. About 60% of NHL present with aggressive forms, and need immediate therapeutic action. The most common choice of treatment for mature B cell neoplasia is chemotherapy, and particularly the multidrug R-CHOP, but ",{"id":391,"funder":7,"programme":8,"title":392,"piName":10,"institution":393,"country":93,"year":13,"amount":14,"abstract":394},"cordis-european-research-council-award-713732","Sieving neuronal network communication","TECHNISCHE UNIVERSITEIT EINDHOVEN","This project will demonstrate the technical and commercial viability of the MESOTAS-SIEVE bioreactor, a novel 3D brain-on-chip microculture system. This allows the culturing and in vitro functional analysis of neuronal networks that mimic the human brain in a physiologically much more relevant way than conventional cell culture systems or animal models. Therefore, the  MESOTAS-SIEVE system has great potential towards the realisation of tissue models of the brain for drug efficacy and toxicity as",{"id":396,"funder":7,"programme":8,"title":397,"piName":10,"institution":398,"country":54,"year":13,"amount":399,"abstract":400},"cordis-european-research-council-award-737439","On a Nuclear Waste Deep Repository Simulator","CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA","€149,250","Nuclear waste is generated during the operation and maintenance of nuclear power plants. The waste is first transferred to an interim storage, where it remains for tens of years, till radioactivity and heat generation of the spent fuel is reduced to a level that allows its final disposal. It is generally accepted that the final waste will be disposed of in a deep geological repository. However, not a single country worldwide has an operational underground repository. In the design process of the",{"id":402,"funder":7,"programme":8,"title":403,"piName":10,"institution":404,"country":352,"year":13,"amount":405,"abstract":406},"cordis-european-research-council-award-727246","Metal Assisted chemical etching of Gratings for X-ray InterferometriC systems","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","€149,997","Phase contrast and scattering-based (dark-field) X-ray imaging can potentially revolutionize the radiological approach to medical imaging because they are intrinsically capable of detecting subtle differences in the electron density of a material and of measuring the effective integrated local small-angle scattering power generated by the microscopic density fluctuations in the specimen. Within the context of the ERC-Starting Grant PhaseX (310005) we deeply investigated and further developed gra",{"id":408,"funder":7,"programme":8,"title":409,"piName":10,"institution":98,"country":99,"year":13,"amount":14,"abstract":410},"cordis-european-research-council-award-693436","Effective Multidrug Cocktails for Cancer","Cancer is a global epidemic that affects all ages and socio-economic groups. In turn, tremendous resources are being invested in prevention, diagnosis, and treatment of cancer. For instance, over 1,000 anticancer drugs are currently in various phases of development and pre-approval testing, more than the number for heart disease, stroke, and mental illness combined. Finding multi-drug combinations for cancer is an increasingly pressing therapeutic challenge. However, screening all possible drug ",{"id":412,"funder":7,"programme":8,"title":413,"piName":10,"institution":414,"country":20,"year":13,"amount":415,"abstract":416},"cordis-european-research-council-award-700812","Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","€149,634","The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand has remained a research i",{"id":418,"funder":7,"programme":8,"title":419,"piName":10,"institution":420,"country":93,"year":13,"amount":14,"abstract":421},"cordis-european-research-council-award-713738","Artificial Dielectrics for High-frequency On-Chip antennas","TECHNISCHE UNIVERSITEIT DELFT","High-speed wireless communication and automotive radars are two applications with huge social and market potentials that can be revolutionized by the development of high-frequency (sub-terahertz) technology. Despite the recent advances in low-cost integrated circuits, the poor performance of on-chip antennas is nowadays the major bottleneck in converting the electrical signals (on-chip) into radiated ones (off-chip). For decades the problem of “surface waves” has prevented the efficient use of r",{"id":423,"funder":7,"programme":8,"title":424,"piName":10,"institution":420,"country":93,"year":13,"amount":425,"abstract":426},"cordis-european-research-council-award-693561","Rationally designed nanostructured catalysts for bio-conversion systems: assessing the innovation potential of Atomic Layer Deposition (ALD) powder\u002Fparticle coatings for the catalyst market","€149,550","The introduction of biomass-derived feedstocks for the production of liquid fuels and chemicals brings new challenges to the chemical industry: the conventional heterogeneous catalysts used in past petrochemical operations often cannot be adopted. Demanding operation conditions cause extensive deactivation problems, while in the same time material scarcity is severely pressing for advances in the utilization efficiency of the active catalyst materials.The understanding of the interplay between a",{"id":428,"funder":7,"programme":8,"title":429,"piName":10,"institution":430,"country":325,"year":13,"amount":10,"abstract":431},"cordis-european-research-council-award-727420","2D nanomaterials-based composite films for more efficient thermal conduction","THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN","The aim of this proposal is to determine the economic and technical feasibility of using readily scalable technologies for the development of inexpensive and high performance solutions for heat dissipation for the high-end automobile industry, as well as other markets including household appliances, injection moulding, advanced aircraft and pharmaceutical manufacturing, ranging from the actual fabrication protocols, down to a wide range of finite products. The technology here described is focuss",{"id":433,"funder":7,"programme":8,"title":434,"piName":10,"institution":35,"country":20,"year":13,"amount":158,"abstract":435},"cordis-european-research-council-award-712718","LAser Systems for Focused Ion and Electron Beams","This ERC Proof of Concept (PoC) Grants should maximize the value of the research performed in the funded ERC Coldnano project by establishing viability of the future industrial product, by solving technical issues concerning the laser systems, by clarifying IPR position and strategy and by budgeting commercial discussion between partners.Industrialization of combined FIB and atom manipulation techniques of laser cooling require special knowledge that will be study by the PI with collaboration an",{"id":437,"funder":7,"programme":8,"title":438,"piName":10,"institution":35,"country":20,"year":13,"amount":439,"abstract":440},"cordis-european-research-council-award-727480","FLUOrinated SURFactant formulations for droplet-based microfluidics","€145,821","Droplet-based microfluidics is a key emerging technology for the miniaturization and automation of biochemical assays.The limiting factor for industrial applications of the technology is not the device aspect but rather the robust control ofemulsion formulations to be used in these devices.Existing formulation solutions available on the market are far from being mature enough to fully convince and satisfy theend-user. The ERC project SOFI has resulted in the fundamental understanding of the dyna",{"id":442,"funder":7,"programme":8,"title":443,"piName":10,"institution":444,"country":65,"year":13,"amount":445,"abstract":446},"cordis-european-research-council-award-677677","Large Scale Protein Library Screening Biosensor","IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE","€149,990","In this application a platform is proposed that builds on preliminary work from ERC starting grant NanoP in order to develop a technology for high throughput electronic recognition of a large library of proteins using nanometer sized channels. These channel (or nanopore) dimensions are on the same order of magnitude as the proteins that we are using, making a natural confinement mechanism. Importantly, this allows for the efficient detection and screening of individual protein molecules and as w",{"id":448,"funder":7,"programme":8,"title":449,"piName":10,"institution":86,"country":87,"year":13,"amount":14,"abstract":450},"cordis-european-research-council-award-713755","Alzheimer’s disease and AAV9: Use of a virus-based delivery system for vectored immunoprophylaxis in dementia.","Alzheimer’s disease (AD) is the most common form of dementia in the Western World, representing an economic and social cost of billions of euros a year. Given the changing demographics of society, these costs will only increase over the coming decades.Amyloid plaques, composed of amyloid beta peptide (Abeta), are a defining characteristic of AD. Evidence now suggests that Abeta is central to disease pathogenesis due to its toxicity, which leads to cell loss and eventual cognitive decline. Abeta ",{"id":452,"funder":7,"programme":8,"title":453,"piName":10,"institution":454,"country":65,"year":13,"amount":455,"abstract":456},"cordis-european-research-council-award-713664","A new cryoprotectant formulation for the next generation of high throughput screening toxicology tests","UNIVERSITY OF LEEDS","€149,926","All pharmaceutical, chemical and cosmetic products have to undergo rigorous toxicity testing before going to market. In the past, this was often done through testing with animals, but this approach has been in rapid decline. The alternative is testing of products for toxicity against mammalian cells in multi-well plates. This technique is very important in the pharmaceutical industry where early detection of drug toxicity can reduce the cost of bringing drugs to market. Testing against hepatocyt",{"id":458,"funder":7,"programme":8,"title":459,"piName":10,"institution":157,"country":54,"year":13,"amount":21,"abstract":460},"cordis-european-research-council-award-713423","Biologically inspired chiral oxidation catalysts for commercial applications of fine chemistry","The ERC-funded project BIDECASEOX ERC-239910 has produced a series of chiral catalysts with broad applicability in various commercial fields associated with synthetic organic chemistry. These catalysts are based in earth abundant metals and activate hydrogen peroxide to perform asymmetric introduction of oxygen atoms into readily available and cheap non chiral organic molecules, producing highly valuable chiral products, leaving water as the only byproduct. By virtue of these reactions, valuable",{"id":462,"funder":7,"programme":8,"title":463,"piName":10,"institution":464,"country":54,"year":13,"amount":358,"abstract":465},"cordis-european-research-council-award-712984","Personified Self Interaction","UNIVERSITAT DE BARCELONA","This proof of concept is based on the ERC Advanced Grant TRAVERSE (2009-2015). It will exploit immersive virtual reality in a new form of psychological clinical intervention akin to Gestalt Therapy.  The primary aim of this Proof of Concept project is to generate a business model that would allow us to diffuse our technology to thousands of counsellors and psychologists around the world. In order to accomplish that we commission further trials to extend the evidence base of the approach, investi",{"id":467,"funder":7,"programme":8,"title":468,"piName":10,"institution":469,"country":93,"year":13,"amount":14,"abstract":470},"cordis-european-research-council-award-694045","On-Chip Cytometry Printed On Demand","UNIVERSITEIT TWENTE","Cytometry (the characterisation and counting of cells) is essential to clinical diagnostics, biotechnology, food industry, water monitoring and many fields of research. Within the ERC Starting Grant, InstantCount, inkjet printing methods have been developed, which allow us to fabricate cell counting chambers with on-chip sample preparation, simplifying cell counting procedures tremendously. By effectively eliminating all sample preparation steps and efficient usage of reagents CyPod promises low",{"id":472,"funder":7,"programme":8,"title":473,"piName":10,"institution":474,"country":65,"year":13,"amount":14,"abstract":475},"cordis-european-research-council-award-692914","European Union Case Law Corpus: creating a multilingual and searchable corpus of case law from EU member state courts and the European Court of Justice.","THE UNIVERSITY OF BIRMINGHAM","The idea to be taken to proof of concept is to develop and test an innovative EU Case Law Corpus (EUCLCORP). EUCLCORP will be a standardised, multidimensional and multilingual corpus of the case law of the Court of Justice of the European Union (CJEU) and of the constitutional\u002Fsupreme courts of EU member states. Unlike databases, in which users can carry out only relatively straightforward searches, for the occurrence of specific terms or keywords, corpora allow users to search and track how par",{"id":477,"funder":7,"programme":8,"title":478,"piName":10,"institution":479,"country":480,"year":13,"amount":14,"abstract":481},"cordis-european-research-council-award-713612","A novel muscle disorders 3D in vitro system for drug screening and validation.","INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES","PT","MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a huge socioeconomic burden. Currently there is a lack of therapeutic options for the majority of patients. This is, for an important part, due to the lack of reliable, reproducible, and physiological relevant in vitro models of muscle disorders that accurately reflect the ",{"id":483,"funder":7,"programme":8,"title":484,"piName":10,"institution":214,"country":65,"year":13,"amount":485,"abstract":486},"cordis-european-research-council-award-693579","GroundForce: Grounding Natural Language Semantics in Video Games","€149,867","While language is a natural way to interact with artificial charactersor agents in video games, communication with agents currently tends tobe limited to menu systems. To achieve smooth linguisticcommunication, utterances need to be grounded in the situation inwhich they occur. That is, the meanings of utterances must be learnedfrom observing their use in some naturally occurring perceptualcontext. Recent years have seen much progress in the development ofvisually- or auditorily-grounded languag",{"id":488,"funder":7,"programme":8,"title":489,"piName":10,"institution":255,"country":93,"year":13,"amount":14,"abstract":490},"cordis-european-research-council-award-713303","MicroRNA Isoforms for Molecular Interception of Cervical cancer using Self-samples","With 13,000 deaths each year in the EU, cervical cancer (CC) is one of the deadliest cancers worldwide. This is unnecessary, since CC is well detectable and treatable at early stages. For this reason, most EU countries have screening programs in place. These screening programs have had (varying) success in reducing CC incidence, however, this reduction has reached a plateau and new strategies are needed to improve screening success.An important reason for the stagnating decline in CC incidence i",{"id":492,"funder":7,"programme":8,"title":493,"piName":10,"institution":494,"country":495,"year":13,"amount":14,"abstract":496},"cordis-european-research-council-award-693555","Proof of Concept study for ERC NIPD discovered biomarkers","NIPD GENETICS PUBLIC COMPANY LIMITED","CY","Scientific and medical evidence indicate that non-invasive prenatal testing, known as non-invasive prenatal testing (NIPT), is a safer alternative to invasive tests that might put the pregnancy at risk. Modern NIPT examine traces of fetal DNA in the maternal bloodstream to determine whether the fetus is at risk of chromosomal abnormalities such as, but not limited to, Down syndrome (trisomy 21), Patau syndrome (trisomy 13) and Edward’s syndrome (trisomy 18). In this ERC Proof of Concept Grant (m",{"id":498,"funder":7,"programme":8,"title":499,"piName":10,"institution":189,"country":65,"year":13,"amount":500,"abstract":501},"cordis-european-research-council-award-693426","Playfields: Prototyping a location based game for higher education.","€149,681","The idea for this Proof of Concept (PoC) is to develop a prototype of a location-based game (LBG) that can be used for teaching fieldwork in a Higher Education (HE) setting. The rationale behind it is that location-based games, understood here as  pervasive games in which gameplay develops through a player's mobile location, are promising educational tools for fieldwork, as they:-Are close to student’s lifestyle as digital natives -Offer innovative and creative technologies for using methods in ",{"id":503,"funder":7,"programme":8,"title":504,"piName":10,"institution":505,"country":352,"year":13,"amount":399,"abstract":506},"cordis-european-research-council-award-713486","Light-Responsive Adhesives for Debond-on-Demand Solutions","UNIVERSITE DE FRIBOURG","Adhesives that debond-on-demand through application of an external stimulus are highly relevant for manufacturing (semiconductor, automotive, aerospace, construction, packaging, sportswear), healthcare applications (wound dressing, transdermal patches), and numerous other domains, and they can significantly contribute to the sustainable use of materials (repairing, reworking, recycling). In all cases, there is a technological need for effective and environmentally benign solutions that provide s",{"id":508,"funder":7,"programme":8,"title":509,"piName":10,"institution":404,"country":352,"year":13,"amount":510,"abstract":511},"cordis-european-research-council-award-693455","Automatically Interactivised and Individualised Videos","€149,876","InInVi originates from augmented reality (AR) research within the ERC project VarCity. Our findings from VarCity of highly robust plane tracking combined with state-of-the-art object recognition enables very robust and qualitatively very high augmentations. In this PoC project, we transfer these findings into commercial applications in the live TV production business. Here, mechanical, inflexible solutions dominate to create overlays or AR animations, for instance step sensors to measure the fie",{"id":513,"funder":7,"programme":8,"title":514,"piName":10,"institution":515,"country":93,"year":13,"amount":516,"abstract":517},"cordis-european-research-council-award-693303","Translation of a fluorescent MYelin specific peripheral NERVE tracer","ACADEMISCH ZIEKENHUIS LEIDEN","€140,000","Tracers that enable imaging of peripheral nerve structures have the potential to reduce the occurrence of perioperative peripheral nerve injury. Hence, through such a fluorescence-guided surgery technique morbidity and related follow up costs may be reduced and the quality of life of patients can be improved. The ability to visualize peripheral nerves also creates nerve-sparing opportunities for surgeons and opens up new commercial-avenues for companies involved in the surgical market. The aim o",{"id":519,"funder":7,"programme":8,"title":520,"piName":10,"institution":521,"country":65,"year":13,"amount":522,"abstract":523},"cordis-european-research-council-award-727296","Quaternary Amino Acids on Scale for Medicine and Agroscience","UNIVERSITY OF BRISTOL","€149,918","Enantiopure quaternary amino acids, carrying two carbon-based substituents at the α carbon, are one of the most important groups of modified α amino acids, of great commercial value in the development of new pharmaceuticals and agrochemicals. Certain of these quaternary amino acids are readily available by stereoselective α alkylation of available amino acids, but not those functionalized by the addition of α-aryl groups. In this project, we propose to develop an industrially scalable, practical",{"id":525,"funder":7,"programme":8,"title":526,"piName":10,"institution":527,"country":105,"year":13,"amount":14,"abstract":528},"cordis-european-research-council-award-692987","Frequency Recognition Algorithm for Multiple Exposures","LUNDS UNIVERSITET","This proof of concept (PoC) project seeks to explore the possibility of commercializing an optical imaging instrument with the unique ability of permitting a single detector to acquire and store several images simultaneously. This new concept, which is named Frequency Recognition Algorithm for Multiple Exposures (FRAME), employs an image-coding strategy, where different exposures are given a unique structural “code”. Thanks to this novel coding approach, the camera sensor may be exposed to light",{"id":530,"funder":7,"programme":8,"title":531,"piName":10,"institution":346,"country":105,"year":13,"amount":10,"abstract":532},"cordis-european-research-council-award-693454","Gap Waveguides for Point-To-Point Wireless Links at 60 GHz and beyond","Our idea is to enable the next generation of mobile network infrastructure for high speed data communication through theuse of a new technology platform called gap waveguides. The demand for mobile data is growing rapidly and operators seetheir costs for mobile infrastructure rising. To meet the demand, and at the same time manage costs, the industry is lookingat an increased adoption of smaller, more cost-efficient mobile base stations (small cells) closer to the end-user. These areexpected to ",{"id":534,"funder":7,"programme":8,"title":535,"piName":10,"institution":536,"country":93,"year":13,"amount":14,"abstract":537},"cordis-european-research-council-award-692671","Empowering expectations for health and disease: Development of a pioneering training tool","UNIVERSITEIT LEIDEN","Expectations about health and disease are known to directly affect health and treatment outcomes. In the EXPECT-HEALTH project, my research group is unravelling the central mechanisms of how expectations affect immune and endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. Ultimate goal of gaining this knowledge is to apply it in innovative therapeutic interventions. In order to reach this goal, an innovati",{"id":539,"funder":7,"programme":8,"title":540,"piName":10,"institution":541,"country":12,"year":13,"amount":14,"abstract":542},"cordis-european-research-council-award-713707","Rapid Antimicrobial susceptibility testing and phylogenetic Identification","HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH","Emerging resistance towards antimicrobials marks this decade and the lack of therapy options especially against gram-negative pathogens underscores the need for optimization of current diagnostics, therapies and prevention of the spread of these organisms. In this proposal the PIs medical microbiology background and previous ERC-funded work on molecular resistance markers is exploited towards the development of a diagnostic assay for resistance profiling and genotyping. The implementation of the",{"id":544,"funder":7,"programme":8,"title":545,"piName":10,"institution":86,"country":87,"year":13,"amount":14,"abstract":546},"cordis-european-research-council-award-713758","Translating fundamental insights in endothelial metabolism: PFKFB3 drug discovery and development","Angiogenesis, the growth of new blood vessels, contributes to major pathologies such as blinding ocular disease, inflammation and cancer. Blocking angiogenesis has therefore become a major field of research and an attractive therapeutic strategy. Current anti-angiogenic therapies focus on blockade of pro-angiogenic factors, such as VEGF. However, in cancer, insufficient efficacy, resistance and toxicity restrict the success of anti-VEGF agents. There is thus an urgent unmet need for novel anti-a",{"id":548,"funder":7,"programme":8,"title":549,"piName":10,"institution":373,"country":93,"year":13,"amount":14,"abstract":550},"cordis-european-research-council-award-665587","APPROAcH: Antimicrobial and Save 3D-Printable Polymers for Oral Health","A major problem in dental care restorations is bacterial infiltration. Bacteria between the tooth and the restoration is a potential cause of postoperative sensitivity, pulp inflammation, and necrosis. In orthodontics, the formation of biofilms during treatment bears the risk of enamel decalcification, cavity formation, and gingival inflammation due to the fact that colonized bacteria are extremely hard to remove in presence of orthodontic appliances. Another related problem is that the current ",{"id":552,"funder":7,"programme":8,"title":553,"piName":10,"institution":554,"country":65,"year":13,"amount":555,"abstract":556},"cordis-european-research-council-award-713743","Carbon dioxide utilisation as a soft oxidant in alkene production","CARDIFF UNIVERSITY","€149,380","The idea is to bring to pre-commercial stage a highly effective, economically feasible catalyst for the production of alkenes,while simultaneously utilizing CO2 as a soft oxidant, developed under the ERC Advanced Grant –‘After the Goldrush’ (ERC-2011-AdG-291319). Initial studies have identified novel catalysts that can be used for formation of propene from propane using CO2 as an oxidant. This has significant societal, environmental and economic benefits, as it makes the commercialisation of the",{"id":558,"funder":7,"programme":8,"title":559,"piName":10,"institution":174,"country":93,"year":13,"amount":560,"abstract":561},"cordis-european-research-council-award-680872","NeMoFoil: electronic foil for neuromonitoring","€149,060","For certain neurological disorders it is necessary to record electrical signals directly from the brain. Intracranial neuromonitoring is indicated for several neuropathologies, such as for localization of the source of seizures in epilepsy patients for surgical removal, or closely watching neurological status in intensive care (eg stroke, brainswelling), typically lasting days to weeks. For this, special electrodes embedded in silicon sheets (‘grids’) are surgically placed between the brain and ",{"id":563,"funder":7,"programme":8,"title":564,"piName":10,"institution":565,"country":87,"year":13,"amount":14,"abstract":566},"cordis-european-research-council-award-713627","Enhancing Large-scale chemical Reactions based on Elementary Kinetics","UNIVERSITEIT GENT","A proof-of-concept software tool for microkinetic model construction, ready for commercialization will be developed starting from an available version of the tool that has been validated in an academic research context.A detailed understanding of the elementary steps involved in large-scale chemical reactions provides several advantages: it may not only lead to a better control of the corresponding processes and, hence, safer operation, it also provides a sound basis for enhanced process design.",{"id":568,"funder":7,"programme":8,"title":569,"piName":10,"institution":570,"country":12,"year":13,"amount":10,"abstract":571},"cordis-european-research-council-award-713239","Small satellites’ strategic analysis of realization potential and commercialization techniques","ZENTRUM FUR TELEMATIK EV","A formation of small satellites, as developed within the ERC Advanced Grant NetSat, promises great market potential because of failure tolerance and low cost at the same time, and large growth prospects for small satellites - a disruptive technology with the potential to change current “rules of the game”, becoming a feasible option for industrial application thanks to tremendous cost reductions as compared to large satellites (lower weight, shorter development cycles\u002F time-to-market, and lower ",{"id":573,"funder":7,"programme":8,"title":574,"piName":10,"institution":230,"country":12,"year":13,"amount":399,"abstract":575},"cordis-european-research-council-award-693779","Late Gothic vaults and their complex stone members: Recovering historical design procedures, implementing knowledge in restoration practice","The proposal aims to transfer the results of the scientific research on design procedures of Late Gothic vaults into the practice of restoration of the architectural heritage. These structures are extremely complex in their geometry, with complicated meshes of ribs soaring along three-dimensional curves and intersecting on multiple levels at the keystones. About the principles of their geometric design and the way of how the instructions for producing their single stone elements were formulated,",{"id":577,"funder":7,"programme":8,"title":578,"piName":10,"institution":579,"country":48,"year":13,"amount":10,"abstract":580},"cordis-european-research-council-award-693670","SILKENE: Bionic silk with graphene or other nanomaterials spun by silkworms","UNIVERSITA DEGLI STUDI DI TRENTO","The project aims at designing, developing, scaling-up and optimizing a pre-industrial process towards the mass production of “silkene”, a bionic silk fiber reinforced with graphene, or other nanomaterials such as nanotubes, directly spun by silkworms. The idea is simply based on nanomaterial ingestion and subsequent “silkene” spinning by silkworms. Silkene is expected to be significantly stronger and tougher that its natural counterpart. Since silk produced by silkworms has already impacted our ",{"id":582,"funder":7,"programme":8,"title":583,"piName":10,"institution":584,"country":12,"year":13,"amount":10,"abstract":585},"cordis-european-research-council-award-712708","Concrete micromolds for microinjection molding","UNIVERSITAT BAYREUTH","Microinjection molding is the current standard technology for the production of microcomponents. There is an increasing demand for microcomponents with feature sizes down to micrometers due to a general trend towards miniaturization in the medical and automotive industry. The main problem to meet this demand is the considerable fix-cost of the micromolds (microstructured injection tool inserts). Currently, the methods for their fabrication are lithography-based LIGA-techniques, electrical discha",{"id":587,"funder":7,"programme":8,"title":588,"piName":10,"institution":589,"country":65,"year":13,"amount":590,"abstract":591},"cordis-european-research-council-award-737574","Wave-based Room Acoustics Modeling","THE UNIVERSITY OF EDINBURGH","€149,138","Virtual acoustics is the complete simulation of the listener’s experience in an acoustic space. The applications are many: building acoustics, concert hall design, and virtual reality, including immersive game audio. Conventional audio rendering approaches are based on geometric or ray-based approximations. Though conceptually simple, such methods neglect many audible features of room acoustics, and in particular are not valid at low audible frequencies, or capable of rendering diffraction or sh",{"id":593,"funder":7,"programme":8,"title":594,"piName":10,"institution":595,"country":105,"year":13,"amount":14,"abstract":596},"cordis-european-research-council-award-692908","COmmercializing first-in-class dCTPase Inhibitors for treatment of hematological Cancers","KAROLINSKA INSTITUTET","In our ERC grant GEnetic NEtworks as a tool for anti-CAncer Drug Development we used siRNA screening and geneticnetworks to identify dCTPase being involved in DNA repair and replication. Further studies revealed that dCTPase plays arole in the degradation of nucleoside analogues used in cancer treatment. We then used an RNAi approach to validatedCTPase as a target to improve nucleoside analogue therapy. The dCTPase protein was purified and we set up anenzymatic high-throughput assay to screen >6",{"id":598,"funder":7,"programme":8,"title":599,"piName":10,"institution":479,"country":480,"year":13,"amount":600,"abstract":601},"cordis-european-research-council-award-713691","Drug Repurposing for Malaria Chemoprotection","€145,500","Malaria is a serious parasitic disease afflicting 198 million people in 2013, with an estimated death toll of approximately 600 000. Approximately half the world’s population is at risk of malaria. So far there is no cure\u002Fvaccine against malaria and current chemoprotective treatments have shortcomings, such as: 1) Limited Number of Drugs effective against malaria parasites; 2) Adverse Side Effects (observed in 32% to 44% of users); 3) Parasite Resistance to most of the drugs used for prevention ",{"id":603,"funder":7,"programme":8,"title":604,"piName":10,"institution":605,"country":48,"year":13,"amount":14,"abstract":606},"cordis-european-research-council-award-713734","Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophy","HUMANITAS MIRASOLE SPA","Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophyCardiovascular diseases (CDs) are growing problems worldwide, affecting as much as 1% of the population. The causes include ischemic, toxic, genetic, post-inflammatory and structural defects; often multiple etiologies are present within an individual patient germane to the contraction failing, resulting in a mortality of ca. 50% within 5 years from diagnosis. Unexpected roles have been unveiled for microRNAs,",{"id":608,"funder":7,"programme":8,"title":609,"piName":10,"institution":111,"country":12,"year":13,"amount":399,"abstract":610},"cordis-european-research-council-award-713397","Salt Tectonics and Dynamics","Many of the world’s oil and gas reservoirs occur in the vicinity of salt structures within sedimentary basins. Because salt is a weak and low-density rock, it flows on geological timescales and forms kilometre-high structures that strongly deform nearby sedimentary layers. This poses several challenges for the industry:  1) Finding new oil and gas fields requires a geological reconstruction of how the sedimentary basin evolved with time, in order to understand where hydrocarbons formed, how they",{"id":612,"funder":7,"programme":8,"title":613,"piName":10,"institution":614,"country":105,"year":13,"amount":14,"abstract":615},"cordis-european-research-council-award-727818","Dried Blood Spot sampling at home in Therapeutic Drug Monitoring","KUNGLIGA TEKNISKA HOEGSKOLAN","A new disposable sampling device that allows quantitative measurements from Dried Blood Spots (DBS) has been developed with support of the ERC AdG xMEMS.The technology consists of a small microfluidic chip made of laminated structured plastic foils and paper with the specific function to meter and store an exact blood volume as a DBS. The chip can be used directly by a patient to leave a capillary blood sample straight from a finger prick. Thissimplifies blood sampling, offers comfort for the pa",{"id":617,"funder":7,"programme":8,"title":618,"piName":10,"institution":398,"country":54,"year":13,"amount":619,"abstract":620},"cordis-european-research-council-award-737424","ICEBREAKER","€149,954","In the ICEBREAKER Proof of Concept (PoC) we will explore the industrial applicability and potential for commercialization of the computational technology developed in the SAFECON Advanced Grant project (www.cimne.com\u002Fsafecon ) for the study of the navigation of a ship in an iced-sea and the determination of the ice drag of the vessel and the ice-induced resistance on the vessel hull. Up to date a commercial simulation tool including such features for the study of ice-ship interaction situations ",{"id":622,"funder":7,"programme":8,"title":623,"piName":10,"institution":624,"country":54,"year":13,"amount":14,"abstract":625},"cordis-european-research-council-award-713704","HYBRID MAGNETIC SUPERCAPACITORS","UNIVERSITAT DE VALENCIA","The purpose of Hy-MAC is to assess both technical and economic viability of using magnetic nanocomposites based on the combination of carbon nanoforms (graphene) with magnetic nanoparticle  as hybrid supercapacitors. These hybrid magnetic materials have shown to exhibit unique supercapacitive properties, which can be significantly enhanced by application of an external magnetic field. Thus, the specific capacitance increases up to a 500% by applying an external magnetic field. Taking advantage o",{"id":627,"funder":7,"programme":8,"title":628,"piName":10,"institution":404,"country":352,"year":13,"amount":629,"abstract":630},"cordis-european-research-council-award-713643","A cartridge based flow chemistry machine for the automated synthesis of N-heterocycles for drug discovery","€149,040","Saturated N-heterocycles are an important class of compounds and are attractive as scaffolds in the development of new pharmaceuticals. As part of ERC supported research, we identified a new class of chemical reagents – “SnAP Reagents” – that alleviate previous synthetic challenges. These SnAP reagents enable the synthesis of more drug-like saturated N-heterocycles, including some of the most sought after, but most difficult to prepare scaffolds. They have been successfully commercialized and ar",{"id":632,"funder":7,"programme":8,"title":633,"piName":10,"institution":634,"country":65,"year":13,"amount":635,"abstract":636},"cordis-european-research-council-award-692977","ULTRA-WIDE TUNEABLE RANDOM FIBRE LASER","ASTON UNIVERSITY","€149,445","The ULTRATUNE project aims to develop and demonstrate a feasibility of a conceptually new photonic product - random fibre laser that is tunable over record ultra-broad wavelength range. The outstanding tunability characteristics defined by the unique underlying physics of random fibre lasers and the simplicity of the scheme make the proposed device a very attractive light source both for fundamental science and practical applications. Spectral tunability is one of the important features of laser",{"id":638,"funder":7,"programme":8,"title":639,"piName":10,"institution":640,"country":65,"year":13,"amount":641,"abstract":642},"cordis-european-research-council-award-693594","EndoNaut Delivery Platform","UNIVERSITY COLLEGE LONDON","€149,929","Translating intracellular delivery to the marketThe advent of nanotechnology allowed the combination of new chemical and physical tools to engineer carriers able to perform specific functions at the molecular level. In recent years the ERC award ERC-STG-MEViC, helped to develop a powerful new technology called EndoNaut. This can be used to encapsulate and deliver dyes, imaging and contrast agents and drugs. EndoNaut technology consists of pH sensitive polymeric vesicles with the unique character",{"id":644,"funder":7,"programme":8,"title":645,"piName":10,"institution":646,"country":54,"year":13,"amount":647,"abstract":648},"cordis-european-research-council-award-713250","System for the efficient and non-invasive harvesting and RElease of ADherent CELLs controlled by light","ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE","€149,940","The Biopharmaceuticals market is currently valued at about 150,000 million euros with an annual growth rate of 6 %. Biopharmaceutical products are mainly obtained from cells cultured in contained systems. Adherent cells represent an important share of the cell types used in production processes and are the major source of cell therapy products. Productivity of current processes for adherent cells culture lags behind those based on suspension cells and the reasons for this imbalance are to be fou",{"id":650,"funder":7,"programme":8,"title":651,"piName":10,"institution":98,"country":99,"year":13,"amount":14,"abstract":652},"cordis-european-research-council-award-680132","Quantum-dot doped polymer fibers for cheap and bright light sources.","In optical microscopy low-cost solid state LEDs and lasers have replaced traditional light sources. Major drawbacks of such, typically fiber-coupled light sources are poor flexibility, low modularity and high cost. Since a complete separate system is needed for every excitation color, the size of the economical investment is hindering the adoption of the technology directly contributing to improved research quality in multiple disciplines.This PoC project derives from SINSLIM ERC Starting grant ",{"id":654,"funder":7,"programme":8,"title":655,"piName":10,"institution":128,"country":65,"year":13,"amount":656,"abstract":657},"cordis-european-research-council-award-693143","HeartRater: Tools for the systematic evaluation of interoceptive ability","€149,630","The Proof-of-Concept grant seeks to develop a commercializable platform to quantify how sensitive individuals are to their own heartbeats.  This platform will have applications in clinical psychology, personalized medicine and beyond.We each differ in the way we express or control our emotions, in the way we base our decisions on feelings, and react to stress or excitement.  A key determinant of these aspects on our behaviour is our sensitivity to changes in the emotional arousal of our bodies. ",{"id":659,"funder":7,"programme":8,"title":660,"piName":10,"institution":661,"country":480,"year":13,"amount":146,"abstract":662},"cordis-european-research-council-award-713697","Stable Brain-Machine control via a learnable standalone interface","FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD","Non-invasive Brain Machine Interfaces (BMI) bring great promise for neuro-rehabilitation and neuro-prosthesis, as well as for brain control of everyday devices and performance of simple tasks. Over the last 15 years the interest in BMIs has grown substantially, and a variety of interfaces have been developed. The field has been growing dramatically, and market studies reveal an estimated market size of $1.46 billion by 2020. However, non-invasive BMIs have failed to reach the impressive control ",{"id":664,"funder":7,"programme":8,"title":665,"piName":10,"institution":666,"country":81,"year":13,"amount":135,"abstract":667},"cordis-european-research-council-award-693343","QUANTUM OPTICAL MAGNETOMETER FOR MEDICAL APPLICATIONS","KOBENHAVNS UNIVERSITET","Sensitive detection of weak magnetic fields produced by human nerves, eyes and brain has a large potential as a diagnostic tool for bio- and medical applications. However, measurements of magnetic fields have not yet been developed into a ubiquitous tool for medical diagnostics, one of the reasons being that commercially available magnetometers with high enough sensitivity are based on expensive superconducting magnetometers (SQUIDs) which require cryogenic cooling. Within the INTERFACE project ",{"id":669,"funder":7,"programme":8,"title":670,"piName":10,"institution":671,"country":352,"year":13,"amount":14,"abstract":672},"cordis-european-research-council-award-727493","Ultrastable optical frequency comb systems","UNIVERSITE DE NEUCHATEL","The invention of optical frequency combs revolutionized numerous fields in metrology and was honoured by the 2005 Nobel Prize in Physics. Frequency combs have many new emerging applications in optical telecommunications, broadband high-precision spectroscopy and sensing, etc. Monitoring of environmentally relevant gases and pollutants, medical sensing of biomarkers in human breath, or remote sensing of gases relevant for resources exploitation or farming are important areas, in which frequency c",{"id":674,"funder":7,"programme":8,"title":675,"piName":10,"institution":565,"country":87,"year":13,"amount":676,"abstract":677},"cordis-european-research-council-award-693447","Integrated spectroscopic sensors for the risk assessment of fires","€149,685","Most fire deaths are not caused by burns, but by smoke inhalation. Toxic gases in smoke are beside heat and lack of oxygen the major lethal factor in uncontrolled fires. Drones are considered more and more as the ultimate assistants during firefighting operations. Drones or Unmanned Aerial Vehicles (UAV) provide critical top-down perspectives on dangerous areas. This is helpful in dealing with most fires, and especially important and effective when dealing with fires at high risk sites. There is",{"id":679,"funder":7,"programme":8,"title":680,"piName":10,"institution":98,"country":99,"year":13,"amount":14,"abstract":681},"cordis-european-research-council-award-664873","Novel heart regeneration strategies","Heart disease and particularly myocardial infarction, i.e. heart attack, is the leading cause of death in the Western world today. The diminished regenerative potential of the heart begins shortly after birth, when most CardioMyocytes (CMs) cease to proliferate and make a transition from hyperplastic to hypertrophic growth. The Tzahor lab has been intensively exploring novel molecules, compounds as well as the molecular mechanisms that facilitate CM cell division in the adult heart of mammals as",{"id":683,"funder":7,"programme":8,"title":684,"piName":10,"institution":565,"country":87,"year":13,"amount":14,"abstract":685},"cordis-european-research-council-award-713632","High-Speed Architectural Simulation of ARM-based Systems","The goal of this project is to extend the Sniper architectural simulator, previously developed at Ghent University, towards ARM-based systems. Sniper is shown to be fast, accurate and low-complexity for x86 multicore systems; and it is widely used in academia, as well as in industry for high-performance computing processor systems. This project will enhance Sniper to support ARM-based systems and will explore innovation opportunities in the embedded and mobile markets.",{"id":687,"funder":7,"programme":8,"title":688,"piName":10,"institution":268,"country":54,"year":13,"amount":14,"abstract":689},"cordis-european-research-council-award-713539","A novel platform for user-friendly spectroscopy at very low temperatures and under strong magnetic fields","One of the most appealing opportunities in the field of Materials Science is the development of multifunctionality. Thus, it is becoming crucial to characterize materials upon acting on more than one physical property at a time. Magnetoelectric, photomagnetic or photoelectric phenomena are some of the bases of future technologies. Most of the equipment available nowadays for materials characterization includes options to study materials (magnetic, electric, etc.) under light irradiation. However",{"id":691,"funder":7,"programme":8,"title":692,"piName":10,"institution":214,"country":65,"year":13,"amount":693,"abstract":694},"cordis-european-research-council-award-680906","Web-based system for multi-arrangement task for rapid acquisition of subjective judgements.","€149,640","Everyone’s perception of the world is unique. Subjective attributions exert powerful influences on our cognition and behaviour, ranging from implicit biases to explicit decision-making. Psychology, public policy, and marketing have long histories of attempts to measure subjective judgements using questionnaires, in which single items are rated one scale at a time. However, ratings require individuals to translate the richness of their perceptual experience into discrete quantities for each item ",{"id":696,"funder":7,"programme":8,"title":697,"piName":10,"institution":698,"country":20,"year":13,"amount":14,"abstract":699},"cordis-european-research-council-award-680890","DrugSynergy: A data-driven systems biology approach to optimize drug combination strategies","INSTITUT CURIE","The complex physiopathology of human chronic diseases includes networks robustness, feedback loops, and cross-talks, which may induce limited efficacy, resistance, and\u002For excessive toxicity of an individual drug. Learning how to combine drugs in order to improve treatment efficacy and lower undesired toxicity is a major biomedical challenge. Current strategies for drug repositioning and optimization of drug combinations have two man limitations: 1) they mostly use public data and databases, whic",{"id":701,"funder":7,"programme":8,"title":702,"piName":10,"institution":536,"country":93,"year":13,"amount":14,"abstract":703},"cordis-european-research-council-award-693039","Development of a potent dual GCS\u002FGBA2 inhibitor as a best in class Gaucher therapeutic","Gaucher disease (GD) is an autosomal recessive disorder caused by deficient activity of acid glucosylceramidase (GBA1). Most patients feature a non-neuronopathic (type 1) course of disease and are treated by either enzyme replacement therapy (ERT – administration of recombinant GBA1) or substrate reduction therapy (SRT – treatment with the iminosugar, Zavesca or the ceramide mimic, Eliglustat – inhibitors of glucosylceramide synthase (GCS)). These therapeutic agents do not prevent neurological s",{"id":705,"funder":7,"programme":8,"title":706,"piName":10,"institution":707,"country":99,"year":13,"amount":14,"abstract":708},"cordis-european-research-council-award-693423","Improved Over-The-Counter (OTC) Market Integrity and Privacy via cryptographic proofs of computational integrity","TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY","Over-The-Counter (OTC) trading is trading done directly between two parties, without supervision of an exchange. Traders in OTC markets face several types of counterparty risk (Default, Replacement, Settlement and  Liquidity). The technology developed by the PI's ERC-funded research will be applied to solve two basic problems: How to preserve the privacy and anonymity of traders involved in decentralized OTC trading, while improving accountability and transparency. The objective is the creation ",{"id":710,"funder":7,"programme":8,"title":711,"piName":10,"institution":174,"country":93,"year":13,"amount":712,"abstract":713},"cordis-european-research-council-award-678426","The diagnostic potential of miRNAs for early diagnosis of Systemic Sclerosis","€149,190","Systemic sclerosis (SSc) is a life-threatening autoimmune connective tissue disorder of unknown cause, characterised by fibrosis of the skin and internal organs. SSc affects approximately 160.000 patients worldwide and is associated with life-long burden of disease. Early detection of SSc is currently impossible as diagnosis is typically based on a combination of late-stage clinical symptoms. Current diagnostics, however, are based on late clinical manifestations. There is a need for actionable ",{"id":715,"funder":7,"programme":8,"title":716,"piName":10,"institution":717,"country":352,"year":13,"amount":14,"abstract":718},"cordis-european-research-council-award-727722","Printable Perovskite Solar Cells with High Efficiency and Stable Performance","ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE","The unique ability of perovskite solar cells (PSCs) to harvest very efficiently incident solar radiation even with films of only a few hundred nm thickness that can be infiltrated by solution processing onto planar substrates and into screen printable scaffold structures provides strong and unprecedented innovation potential in photovoltaics. Demonstration of high power conversion efficiency at very low cost along with the requisite durability metrics will form a persuasive argument for large in",{"id":720,"funder":7,"programme":8,"title":721,"piName":10,"institution":717,"country":352,"year":13,"amount":269,"abstract":722},"cordis-european-research-council-award-693907","Diffusion Barrier Layers and Anticorrosive Coatings from Functional Carbon Nanosheets","Materials with excellent diffusion barrier properties are highly relevant for packaging applications (food, pharmaceutics), sealing (car tires), protective encapsulation (microelectronics, photovoltaics, displays), and anticorrosive coatings (automotive). In all these fields of application, there is a strong technological demand for more effective, less costly, and environmentally benign solutions, which constitutes a significant business opportunity. The proposed project aims to develop novel b",{"id":724,"funder":7,"programme":8,"title":725,"piName":10,"institution":726,"country":65,"year":13,"amount":14,"abstract":727},"cordis-european-research-council-award-680486","That Special First Time - Boosting Turnout and Satisfaction amongst First Time Voters","LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE","FIRSTTIME is dedicated to generating new unique instruments that Election Management Bodies (EMB) worldwide can use to organise a bespoke electoral experience for first time voters and increase their satisfaction and turnout. We will partner with EMBs to test them in real elections. FIRSTTIME follows on from the INMIVO grant which won accolades such as Best International Research Award from the Market Research Society, led to multiple books, articles in leading journals, and major policy impact ",{"id":729,"funder":7,"programme":8,"title":730,"piName":10,"institution":731,"country":480,"year":13,"amount":158,"abstract":732},"cordis-european-research-council-award-713735","Epithelial resistance modulation to treat disease","UNIVERSIDADE NOVA DE LISBOA","Epithelial barriers are essential for organism’s homeostasis and survival. Defects in resistance of body barrier epithelial tissues and their repair are thought to underlie a range of diseases, which affect millions. Antonio Jacinto’s group has discovered that Septate\u002FTight Junctions are essential for epithelial repair. These cell-cell junctions can be potentially targeted by candidate compounds that have been identified by Thelial, a Start-Up that will collaborate in this project. In EMODI we w",{"id":734,"funder":7,"programme":8,"title":735,"piName":10,"institution":214,"country":65,"year":13,"amount":736,"abstract":737},"cordis-european-research-council-award-693878","Reprogramming cell identity to develop new therapies against Cholangiopathies","€149,907","Intra- hepatic Cholangiocytes represent one of the main cell type of the liver with hepatocytes. They line the biliary tract and fulfill essential functions such as bile modification and transport. Cholangiocytes are targeted by a diversity of diseases including genetic disorders such as Cystic Fibrosis. There is currently no cure for disorders affecting cholangiocytes and end stage disease require liver transplantation. Importantly, primary cholangiocytes obtained from biopsy can not be grown i",{"id":739,"funder":7,"programme":8,"title":740,"piName":10,"institution":741,"country":87,"year":13,"amount":158,"abstract":742},"cordis-european-research-council-award-713601","uPROPHET: Urinary PROteomics in Predicting HEart Transplantation outcomes","KATHOLIEKE UNIVERSITEIT LEUVEN","The proof of concept underlying uPROPHET rests on the EPLORE findings that capillary electrophoresis coupled with high-resolution mass-spectroscopy reproducibly identified unique urinary proteomic (UP) signatures associated with subclinical left ventricular dysfunction, renal impairment and adverse cardiovascular outcomes. Consensus criteria currently applied for the selection of patients for heart transplantation (HTx) leave an inconvenient margin of uncertainty, because of the unpredictable co",{"id":744,"funder":7,"programme":8,"title":745,"piName":10,"institution":746,"country":20,"year":13,"amount":14,"abstract":747},"cordis-european-research-council-award-680465","Development of immunosuppressive treatments with better safety","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","The idea of the proposal is to prove the relevance of the development a novel class of immunosuppressive drugs with a better safety. These agents will aim at selectively inhibit the proliferation of T (and B) lymphocytes by targeting a medically relevant target (named CTPS1) recently identified by Dr Latour in the team of Pr Fischer. Proliferation of T lymphocytes is a normal component of the immune reaction toward an antigen, but in certain circumstances, the proliferation of activated T lympho",{"id":749,"funder":7,"programme":8,"title":750,"piName":10,"institution":444,"country":65,"year":13,"amount":405,"abstract":751},"cordis-european-research-council-award-679417","Wearable  Brain Monitoring Technology for Quick Diagnosis of Sleep Disorders","The standard method of diagnosing sleep disorders involves the patient attending a sleep clinic overnight where he\u002Fshe is hooked by trained specialists to bulky, uncomfortable wired sensors, and monitored during sleep; preferably supervised because the sensors tend to get de-attached and require repositioning. The raw signals are subsequently manually analysed by a medical expert, this taking over 2 hours. Occasionally, for certain diseases the patient is sent home with an ambulatory system whic",142,{"programme":8,"total":754,"withPiName":755,"firstYear":756,"lastYear":757,"countryCount":758,"perYear":759,"topInstitutions":797,"topCountries":865},2347,7,2014,2027,31,[760,762,764,765,768,771,774,777,780,783,786,789,792,795],{"year":756,"count":761},13,{"year":763,"count":752},2015,{"year":13,"count":752},{"year":766,"count":767},2017,200,{"year":769,"count":770},2018,160,{"year":772,"count":773},2019,176,{"year":775,"count":776},2020,174,{"year":778,"count":779},2021,120,{"year":781,"count":782},2022,198,{"year":784,"count":785},2023,231,{"year":787,"count":788},2024,237,{"year":790,"count":791},2025,265,{"year":793,"count":794},2026,264,{"year":757,"count":796},25,[798,801,804,807,810,813,816,819,822,824,826,829,832,835,837,840,843,845,848,850,852,854,857,860,862],{"name":799,"count":800},"Centre National de la Recherche Scientifique CNRS",84,{"name":802,"count":803},"Weizmann Institute of Science",65,{"name":805,"count":806},"Technion - Israel Institute of Technology",43,{"name":808,"count":809},"The Chancellor Masters and Scholars of the University of Cambridge",42,{"name":811,"count":812},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",41,{"name":814,"count":815},"Fondazione Istituto Italiano di Tecnologia",34,{"name":817,"count":818},"Tel Aviv University",33,{"name":820,"count":821},"Imperial College of Science Technology and Medicine",32,{"name":823,"count":821},"Politecnico di Milano",{"name":825,"count":758},"Institut National de la Sante Et de la Recherche Medicale",{"name":827,"count":828},"Ecole Polytechnique Federale de Lausanne",30,{"name":830,"count":831},"Universiteit Twente",29,{"name":833,"count":834},"The Hebrew University of Jerusalem",28,{"name":836,"count":834},"Universiteit Gent",{"name":838,"count":839},"The Chancellor, Masters and Scholars of the University of Oxford",27,{"name":841,"count":842},"Danmarks Tekniske Universitet",24,{"name":844,"count":842},"Vib Vzw",{"name":846,"count":847},"Katholieke Universiteit Leuven",23,{"name":849,"count":847},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",{"name":851,"count":847},"Technische Universitaet Muenchen",{"name":853,"count":847},"Technische Universiteit Delft",{"name":855,"count":856},"The Provost, Fellows, Foundation Scholars & the Other Members of Board, of the College of the Holy & Undivided Trinity of Queen Elizabeth Near Dublin",22,{"name":858,"count":859},"Technische Universiteit Eindhoven",21,{"name":861,"count":859},"Universiteit Leiden",{"name":863,"count":864},"Eidgenoessische Technische Hochschule Zuerich",20,[866,868,870,872,874,876,878,880,882,884,886,888,890,892,894,896,897,900,903,905,908,911,914,916,919],{"name":12,"count":867},299,{"name":54,"count":869},273,{"name":65,"count":871},261,{"name":93,"count":873},254,{"name":48,"count":875},221,{"name":20,"count":877},215,{"name":99,"count":879},191,{"name":87,"count":881},109,{"name":352,"count":883},85,{"name":105,"count":885},72,{"name":117,"count":887},62,{"name":81,"count":889},50,{"name":325,"count":891},48,{"name":152,"count":893},47,{"name":480,"count":895},40,{"name":196,"count":864},{"name":898,"count":899},"TR",19,{"name":901,"count":902},"NO",17,{"name":495,"count":904},12,{"name":906,"count":907},"CZ",11,{"name":909,"count":910},"LU",10,{"name":912,"count":913},"PL",8,{"name":915,"count":913},"SI",{"name":917,"count":918},"HU",5,{"name":920,"count":921},"HR",2]