[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-erc-starting-grant-2020":3,"awarded-stats-erc-starting-grant":1107},{"awarded":4,"total":1106},[5,16,23,28,33,38,43,48,55,60,67,72,77,83,89,96,103,108,113,119,124,129,135,140,145,151,157,162,167,172,177,183,189,196,202,208,215,221,228,234,239,244,249,254,259,264,270,277,284,290,296,302,308,314,320,326,332,338,344,349,355,359,364,370,376,381,387,393,398,403,408,412,418,424,429,434,439,444,449,454,459,464,469,474,479,486,491,496,500,506,510,516,521,527,532,537,542,548,553,559,565,571,578,582,588,594,599,604,609,613,619,624,630,634,640,646,651,656,660,666,671,676,681,687,692,698,703,708,714,720,726,730,736,742,747,752,758,764,769,774,780,786,791,796,802,807,812,818,823,827,832,837,842,847,853,858,862,867,872,877,883,888,894,900,905,910,915,921,927,932,938,944,950,955,961,966,971,977,983,989,995,1002,1008,1014,1019,1025,1030,1035,1041,1047,1053,1058,1064,1068,1074,1080,1085,1091,1096,1101],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-european-research-council-award-850404","European Research Council","ERC Starting Grant","Separating parallel threads of cognition to better explain behaviour",null,"AARHUS UNIVERSITET","DK",2020,"€1,490,515","Our understanding of the neural basis of human cognition and its relation to behaviour is limited by the extent to which we can observe its underlying components. Neural activity elicited by a given stimulus can be decomposed in parallel threads of cognitive computation, each specialising on a different aspect of the stimulus. Conventional methods are fundamentally limited to tease apart these components within the stimulus-specific brain activity, therefore obscuring our understanding of the un",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-european-research-council-award-852791","Extracellular vesicle production and engineering by turbulence for fistula therapy in thermoreversible hydrogels","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","FR","€1,496,094","Extracellular vesicles (EVs) from stem cells (SCs) may recapitulate the therapeutic effect of their mother cells in regenerative medicine while mitigating risks of uncontrolled replication, differentiation and vascular occlusion, offering off-the-shelf, storage and shelf-life gains. Yet, the clinical translation of SC EV therapy is hampered by production, engineering and administration challenges. Building on my preliminary results, ExocyTher aims at developing SC EV therapy through:(1) standard",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":19,"country":20,"year":13,"amount":26,"abstract":27},"cordis-european-research-council-award-851006","Mechanism of homology search and the logic of homologous chromosome pairing in meiosis","€1,499,779","Homologous recombination (HR) is a conserved DNA double-strand breaks (DSB) repair pathway that uniquely uses an intact DNA molecule as a template. Genome-wide homology search is carried out by a nucleoprotein filament (NPF) assembled on the ssDNA flanking the DSB, and whose product is a “D-loop” joint molecule. Beyond accurate DSB repair, this capacity of HR to spatially associates homologous molecules is also harnessed for homolog pairing in meiosis. The goal of “3D-loop” is to tackle two long",{"id":29,"funder":7,"programme":8,"title":30,"piName":10,"institution":19,"country":20,"year":13,"amount":31,"abstract":32},"cordis-european-research-council-award-848645","Label-free quantitative nanoscopy for molecular specific identification at depth in pristine living biological tissues","€1,499,016","Optical microscopy has undergone a revolution that now allows us to access molecular resolution (“nanoscopy”) with the identification of specific biomolecules within biological samples. Nanoscopy has become a key approach to decipher the function of living matter since biomolecules are the elementary building blocks. While being a major tool, high-resolution and specificity can only be achieved by tagging the molecules of interest with fluorescent probes, which inevitably alters the samples, mak",{"id":34,"funder":7,"programme":8,"title":35,"piName":10,"institution":19,"country":20,"year":13,"amount":36,"abstract":37},"cordis-european-research-council-award-850853","Precipitation triggered rock dynamics: the missing mesoscopic link","€1,491,330","Climate change leads to increasing weathering cycles on landscapes and the built environment. Promotion of alternative energy sources such as geothermal energy intensifies cyclic perturbations of the underground environment. Both lead to precipitation-dissolution cycles of salts, natural constituents of brines present inside porous rock. When precipitation occurs inside the pores, stresses build up which eventually crack the material. This might be a positive outcome, e.g., increasing the produc",{"id":39,"funder":7,"programme":8,"title":40,"piName":10,"institution":19,"country":20,"year":13,"amount":41,"abstract":42},"cordis-european-research-council-award-853116","Thermal and Electrical Transport in Correlated Quantum Materials","€1,438,750","The last decade has witnessed a revolution in the prediction and understanding of new phases of matter characterized by topology and entanglement. This includes topological insulators, semimetals, superconductors, quantum spin liquids, topological Kondo systems, etc.. However, most of the theory is directed at the classification of ground state properties and elementary excitations, and most successful experiments are spectroscopic. The big frontier is transport. The latter is the key for nearly",{"id":44,"funder":7,"programme":8,"title":45,"piName":10,"institution":19,"country":20,"year":13,"amount":46,"abstract":47},"cordis-european-research-council-award-852239","Probing the Geochemistry of the First Oceans with Novel ISOtope Proxies in Banded Iron Formations (BIFs): New Perspectives into Early Continental Weathering, Ocean Oxygenation and Mantle Geodynamics","€1,293,750","Since the beginning of Earth’s history, the oceans acted as an interface between the atmosphere, the continents, and the mantle via atmospheric exchange, weathering, sedimentation, and submarine volcanism. Such interactions make the composition of early seawater a unique recorder of the processes that have affected the Earth’s major reservoirs. Yet, this record has not been explored in details. Here, I propose to investigate the geochemistry of the first oceans that is recorded in Precambrian ba",{"id":49,"funder":7,"programme":8,"title":50,"piName":10,"institution":51,"country":52,"year":13,"amount":53,"abstract":54},"cordis-european-research-council-award-945714","Unlikely Intersection and Uniform Bounds for Points","GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER","DE","€1,499,916","I propose to investigate the following long expected but widely open uniform bounds on rational and algebraic points. (1) Mazur’s conjecture on the number of points on curves, which implies the following two strong bounds: (1.i) the number of rational points on a smooth projective curve of genus g at least 2 defined over a number field of degree d is bounded above in terms of g, d and the Mordell- Weil rank; (1.ii) the number of algebraic torsion points on a smooth projective curve of genus g at",{"id":56,"funder":7,"programme":8,"title":57,"piName":10,"institution":19,"country":20,"year":13,"amount":58,"abstract":59},"cordis-european-research-council-award-847433","Topographic effects in planetary fluid cores: application to the Earth-Moon system","€1,448,493","Understanding planetary core flows is crucial as they generate planetary magnetic fields and modify planetary rotation. However, their study is an outstanding challenge involving geomagnetism, geodesy and fluid mechanics. Notably, present models fail to explain two puzzling observations. First, geodesy constrains the Earth and Moon core dissipations to values exceeding those of current theoretical models. Second, lunar paleomagnetism gives an early Moon magnetic field too intense for the current",{"id":61,"funder":7,"programme":8,"title":62,"piName":10,"institution":63,"country":64,"year":13,"amount":65,"abstract":66},"cordis-european-research-council-award-847428","Titles of the New Testament: A New Approach to Manuscripts and the History of Interpretation","UNIVERSITY OF GLASGOW","UK","€1,498,451","The problem this project addresses is that operative modes for interpreting the Greek New Testament (NT) rely upon critical editions, not manuscripts. NT editions are scholarly abstractions that focus on reconstructing an “original” text, and that fail to account for a rich manuscript tradition that preserves evidence for key disciplinary questions. Instead of asking how manuscripts help reconstruct a text, this project examines what manuscripts say about the ways the NT was interpreted by the c",{"id":68,"funder":7,"programme":8,"title":69,"piName":10,"institution":19,"country":20,"year":13,"amount":70,"abstract":71},"cordis-european-research-council-award-852448","A History of Madness in West Africa: Governing Mental Disorder during Decolonisation  (Senegal, Burkina Faso and Ghana - 1940s – 1970s)","€1,469,688","Combining multi-site archival work, the MaDAf project will outline a history of madness in West Africa, during the decolonisation period and after independence. The project will focus on three main areas connected to the history of Africa, decolonisation, and the history of madness: by looking at a the decolonisation and post-independence periods, the project aims firstly to underline the ruptures but also the continuities in the everyday government of madness; it will offer a theoretical framew",{"id":73,"funder":7,"programme":8,"title":74,"piName":10,"institution":19,"country":20,"year":13,"amount":75,"abstract":76},"cordis-european-research-council-award-850934","The importance of cellular sex in physiology and the underlying mechanisms","€1,498,365","The difference between males and females constitutes the largest phenotypic dimorphism in most species. In humans, this variation accounts for differences seen in the risk, incidence and response to treatment for a plethora of diseases; and much of these striking differences are not explained at this time. While sex organ-derived hormones play key roles in sculpting and maintaining sex differences, my recent work highlighted the importance of cell-intrinsic mechanisms involving the sex chromosom",{"id":78,"funder":7,"programme":8,"title":79,"piName":10,"institution":80,"country":20,"year":13,"amount":81,"abstract":82},"cordis-european-research-council-award-850925","Majoration-Minimization algorithms for Image Processing","INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE","€1,500,000","Mathematical optimization is the key to solving many problems in science, based on the observation that physical systems obey a general principle of least action. While some problems can be solved analytically, many more can only be solved via numerical algorithms. Research in this domain has proved essential over many years. In addition, science in general is changing. Increasingly, in biology, medicine, astronomy, chemistry, physics, large amounts of data are collected by constantly improving ",{"id":84,"funder":7,"programme":8,"title":85,"piName":10,"institution":86,"country":52,"year":13,"amount":87,"abstract":88},"cordis-european-research-council-award-852798","Transcription-replication conflicts in disease and development","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","€1,497,530","Genetic and epigenetic instability contribute to cancers, aging, developmental disorders, and neurological diseases, so in-depth understanding how this instability arises is an important question affecting millions in Europe. Physical conflicts between the transcription and DNA replication machineries are a potent endogenous source of this instability.My preliminary data indicate that a single collision can trigger long-term epigenetic changes and affect the normal expression state of genes. I h",{"id":90,"funder":7,"programme":8,"title":91,"piName":10,"institution":92,"country":93,"year":13,"amount":94,"abstract":95},"cordis-european-research-council-award-849165","New opportunities to enhance or extend (mobile) web survey data and get better insights","UNIVERSIDAD POMPEU FABRA","ES","€1,497,625","The expansion of the Internet and the development of a range of new active and passive measurement tools, particularly on mobile devices, present exciting opportunities for survey researchers, such as visual or geolocation data capture. Using these new measurement opportunities could reduce respondent burden, improve data quality, and extend measurement into new domains, allowing to answer questions that could not be answered so far and to improve the decisions of key actors (e.g. government). T",{"id":97,"funder":7,"programme":8,"title":98,"piName":10,"institution":99,"country":100,"year":13,"amount":101,"abstract":102},"cordis-european-research-council-award-948783","Comprehending Prokaryotic Argonaute Systems","WAGENINGEN UNIVERSITY","NL","€1,496,463","Eukaryotic Argonaute proteins are known for their central role in RNA interference pathways. Yet, the evolutionary origin of Argonaute proteins lies in prokaryotes, where other proteins essential for RNA interference are absent. Therefore, prokaryotic Argonaute proteins (pAgos) must have distinct ancestral functions. Although a handful of closely related pAgos interfere with exogenous DNA invaders such as plasmids, pAgos are extremely diverse in terms of sequence conservation and domain architec",{"id":104,"funder":7,"programme":8,"title":105,"piName":10,"institution":99,"country":100,"year":13,"amount":106,"abstract":107},"cordis-european-research-council-award-851004","Local Ecologies of Knowledge: Towards a Philosophy of Ethnobiology","€1,499,934","Indigenous and other local communities possess complex biological knowledge that is increasingly recognized in collaborative approaches in the agricultural, environmental, and health sciences. However, collaborations between local communities and academically trained scientists are commonly challenged by deep differences in epistemologies, ontologies, and value systems. For example, an Indigenous fisher may be an expert on a local marine ecosystem but rely on spiritual fishing norms and metaphys",{"id":109,"funder":7,"programme":8,"title":110,"piName":10,"institution":99,"country":100,"year":13,"amount":111,"abstract":112},"cordis-european-research-council-award-948770","A computational framework to interpret the chemical language of the microbiome","€1,499,965","Humans, animals and plants are covered in microbes. Such microbiomes have a major impact on the health of their hosts and have been linked to traits like growth promotion, stress resilience, and diseases. However, the mechanisms underlying microbiome-host interactions remain poorly understood. Recent studies have shown that microbiome-associated phenotypes are often mediated by specific molecules, a chemical language that enables microbes to interact with each other and with the host. The biosyn",{"id":114,"funder":7,"programme":8,"title":115,"piName":10,"institution":116,"country":93,"year":13,"amount":117,"abstract":118},"cordis-european-research-council-award-851929","Three-dimensional nanoscale design for the all-in-one solution to environmental multisource energy scavenging","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","€1,498,414","Imagine a technology for powering your smart devices by recovering energy from lights in your office, the random movements of your body while reading these lines or from small changes in temperature when you breathe or go out for a walk. This very technology will provide energy for wireless sensor networks monitoring the air in your city or the structural stability of buildings and large constructions remotely and sustainably, avoiding battery recharging or even replacing them. These are the cha",{"id":120,"funder":7,"programme":8,"title":121,"piName":10,"institution":116,"country":93,"year":13,"amount":122,"abstract":123},"cordis-european-research-council-award-853468","Remote control of cellular signalling triggered by magnetic switching","€1,798,454","It is becoming increasingly clear that successful tissue engineering rests on capitalizing on more comprehensive understanding of mechanotransduction and its implication in skin homeostasis. In fact, the study of mechanotransduction is now a burgeoning research field, helping us to understand how cells respond to mechanical stimuli and convert them into biochemical signals, which in turn sheds light on the remote control of intracellular functions and the treatment of diseases. However, external",{"id":125,"funder":7,"programme":8,"title":126,"piName":10,"institution":116,"country":93,"year":13,"amount":127,"abstract":128},"cordis-european-research-council-award-853390","Pathways to Statehood: Authority, legitimacy and Social Diversity in the Horn of Africa (11th-16th centuries)","€1,499,848","The StateHorn Project presents a radically new, archaeology-based approach to one of the key issues in the contemporary world: the nature and characteristics of weak and failed states. Based in the Horn of Africa, an area widely known by recurrent problems of fragmented systems of governance and legitimate authority, the StateHorn project aims to build an alternative vision on the ways statehood has been conceptualized, studied and analyzed in the region. It will do it from a archaeological, dee",{"id":130,"funder":7,"programme":8,"title":131,"piName":10,"institution":132,"country":64,"year":13,"amount":133,"abstract":134},"cordis-european-research-council-award-850930","Fibring of manifolds and groups","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD","€1,498,660","The study of manifolds that fibre over the circle has a long and exciting history at the core of modern manifold topology, starting with Farrell's work on the problem in high ('surgery') dimensions, and running through the celebrated work of Stallings and Thurston in dimension 3, to Agol's 2013 solution of Thurston's virtual fibring conjecture. Parallel developments in group theory have placed the study of Bieri-Neumann-Strebel (BNS) invariants, which emerged in the 1980s, at the heart of the su",{"id":136,"funder":7,"programme":8,"title":137,"piName":10,"institution":132,"country":64,"year":13,"amount":138,"abstract":139},"cordis-european-research-council-award-850869","Using hidden genealogical structure to study the architecture of human disease","€1,499,665","Large-scale genome-wide association studies (GWAS) have yielded thousands of genetic as-sociations to heritable traits, but for most common diseases, these signals collectively explain only a small fraction of phenotypic variation. The phenotypic impact of recent, rare genetic variants, in particular, is poorly understood, but currently available data sets and analytical tools cannot be used to effectively study this class of variation. To address this problem, we propose to develop new computat",{"id":141,"funder":7,"programme":8,"title":142,"piName":10,"institution":116,"country":93,"year":13,"amount":143,"abstract":144},"cordis-european-research-council-award-851255","Air Transport as Information and Computation","€1,297,024","Air transport has by and large been studied as a transportation process, in which different elements, e.g. aircraft or passengers, move within the system. While intuitive, this approach entails several drawbacks, including the need for large-scale simulations, the reliance on real data, and the difficulty of extracting macro-scale conclusions from large quantities of micro- scale results. The lack of a better approach is in part responsible for our inability to fully understand delay propagation",{"id":146,"funder":7,"programme":8,"title":147,"piName":10,"institution":148,"country":64,"year":13,"amount":149,"abstract":150},"cordis-european-research-council-award-852744","Forced Migration and Development","UNIVERSITY COLLEGE LONDON","€1,383,209","The recent forced migration crisis has reached an impressive magnitude: by 2016, 68.5 million individuals had been forcibly displaced by violence, conflict and natural disasters. This crisis is vastly concentrated in developing countries, which host 85% of the world’s displaced population. Nevertheless, we still know relatively little about the economic consequences of forced migration in these countries. FORCEDMIGDEV seeks to fill this gap. It is organised in complementary parts that analyse th",{"id":152,"funder":7,"programme":8,"title":153,"piName":10,"institution":154,"country":64,"year":13,"amount":155,"abstract":156},"cordis-european-research-council-award-849960","Changing elites: how social and institutional change has altered the processes of elite formation over time?","LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE","€1,497,884","Elites reveal the nature of inequality, allowing us to see the underlying structure of society. But, elites can also be the engines of inequality, driving forward changes ensuring the accumulation of power. So, when the people occupying elite positions change it says something about how the production of inequalities may have changed too. Most would agree (despite the paucity of data) that elites are different today than they were; but, what is contested is whether such changes signal a radical ",{"id":158,"funder":7,"programme":8,"title":159,"piName":10,"institution":132,"country":64,"year":13,"amount":160,"abstract":161},"cordis-european-research-council-award-851990","Linguistics from India: new ideas for modern linguistics from ancient India","€1,499,440","This project aims to synthesize expertise and insights from the fields of ancient Indian and modern Western linguistics, to enable deeper understanding and innovation in linguistic theory.An extensive and highly sophisticated linguistic tradition flourished in ancient India between c. 500 BC and 1700 AD. Panini’s grammar the Astadhyayi is often recognized by generative linguists as the earliest generative grammar ever developed, more than 2000 years before Chomsky. Yet beyond this recognition, m",{"id":163,"funder":7,"programme":8,"title":164,"piName":10,"institution":132,"country":64,"year":13,"amount":165,"abstract":166},"cordis-european-research-council-award-851318","Structure in the Primes, with applications","€1,489,402","Questions about prime numbers make up several of the oldest and most important open problems in mathematics. Unfortunately our techniques for solving these problems are very limited; even some of the most basic and simple to state questions about primes are well beyond current techniques. This project studies several different questions related to the distribution of the primes, with the aim of developing new flexible techniques for studying the primes in general. Such new techniques would then ",{"id":168,"funder":7,"programme":8,"title":169,"piName":10,"institution":132,"country":64,"year":13,"amount":170,"abstract":171},"cordis-european-research-council-award-851550","Causes and consequences of variation in the mammalian microbiota","€1,771,166","The mammalian gut teems with a particularly dense and diverse microbial community, the composition of which varies widely among hosts. A large body of laboratory work suggests these communities provide important functions for the host – including nutrition, pathogen protection and immune development – but we know very little about what shapes the mammalian gut microbiota, and how it affects the host, in natural populations. A major barrier to progress is a lack of powerful investigative tools fo",{"id":173,"funder":7,"programme":8,"title":174,"piName":10,"institution":132,"country":64,"year":13,"amount":175,"abstract":176},"cordis-european-research-council-award-850593","Mereological Reconstruction of the Metaphysical System in the Daodejing","€229,500","The project is a mereological reconstruction of the metaphysical system in the Daodejing. The general motivation for the project is to fill the gap in Chinese and comparative philosophy the state of the art, where mereological as well as analytic reconstructions are scarce. The specific motivation is that mereological approach enables precise reconstruction that (a) offers a comprehensive conceptualization of Daoist metaphysical system and (b) allows to generate the issues and plausibly debates ",{"id":178,"funder":7,"programme":8,"title":179,"piName":10,"institution":180,"country":52,"year":13,"amount":181,"abstract":182},"cordis-european-research-council-award-853272","Linking livestock genetic diversity with three thousand years of agricultural crises and resilience","LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN","€1,499,998","Over the last 50 years, chicken production has increased fivefold, chicken growth rate has tripled, and milk production per cow has doubled. Yet, many of the biotechnological tools responsible for this accelerated trend are now under threat of becoming obsolete. While the causes are numerous, one significant driver is a dramatic reduction of genetic diversity in livestock populations.Cycles of agricultural productivity growth and decline have occurred throughout European history, spurred by majo",{"id":184,"funder":7,"programme":8,"title":185,"piName":10,"institution":186,"country":64,"year":13,"amount":187,"abstract":188},"cordis-european-research-council-award-805194","Re-thinking Efficiency in Deep Learning under Accelerators and commodity and processors","THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE","€1,495,036","In just a few short years, breakthroughs from the field of deep learning have transformed how computers perform a wide-variety of tasks such as recognizing a face, driving a car or translating a language. Not only has deep learning become an everyday tool, it is also the most promising direction for tackling a number of still open problems in machine learning and artificial intelligence. However, routine deep learning activities (such as training a model) exert severe resource demands (e.g., mem",{"id":190,"funder":7,"programme":8,"title":191,"piName":10,"institution":192,"country":193,"year":13,"amount":194,"abstract":195},"cordis-european-research-council-award-949645","New Forms of Calligraphy in China: A Contemporary Culture Mirror","ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA","IT","€1,113,750","Calligraphy is a central tenet of Chinese civilization. The whole history of China is strictly linked to the history of its writing and calligraphy. In contemporary times Calligraphy has undergone a radical change and it has evolved into new forms in all fields of visual and performing arts. WRITE will explore how all these forms emerged in: (F1) fine and contemporary arts where it became a naf painting made of pictographic shapes of characters, an abstract combination of dots and lines, a light",{"id":197,"funder":7,"programme":8,"title":198,"piName":10,"institution":199,"country":20,"year":13,"amount":200,"abstract":201},"cordis-european-research-council-award-850941","Low-regularity and high oscillations: numerical analysis and computation of dispersive evolution equations","SORBONNE UNIVERSITE","€1,499,905","Partial differential equations (PDEs) play a central role in mathematics, allowing us to describe physical phenomena ranging from ultra-cold atoms (Bose–Einstein condensation) up to ultra-hot matter (nuclear fusion), from learning algorithms to fluids in the human brain. To understand nature we have to understand their qualitative behavior: existence and long time behavior of solutions, their geometric and dynamical properties – as well as to compute reliably their numerical solution. While line",{"id":203,"funder":7,"programme":8,"title":204,"piName":10,"institution":205,"country":20,"year":13,"amount":206,"abstract":207},"cordis-european-research-council-award-851360","The evolution of menstruation in primates","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","€1,185,250","Menstruation is a recent evolutionary innovation in primates: the trait is present in some species (humans, baboons) but not in closely related others (orangutans, vervets). In the latter and in most mammals, the uterine endometrium is reabsorbed at the end of the cycle instead of being shed when fecundation has not occurred. The molecular and genetic underpinnings of this complex process are not fully understood, despite its critical involvement in gynaecological conditions. I propose to discov",{"id":209,"funder":7,"programme":8,"title":210,"piName":10,"institution":211,"country":212,"year":13,"amount":213,"abstract":214},"cordis-european-research-council-award-852152","Extracellular Vesicles for Bone Regeneration – alternatives to Stem-cell Therapy","UNIVERSITY OF GALWAY","IE","€1,499,925","The therapeutic benefits of mesenchymal stem cells (MSCs), the state-of-the-art treatment for healing bone defects following trauma, resection of cancerous bone tumors, or metabolic bone diseases, has been attributed to their secreted factors. The regenerative potential of MSC-secreted extracellular vesicles (EVs), nanoparticles which deliver bioactive cargo (nucleic acids, proteins, and lipids) between cells, has recently been reported. The applicant will embark upon frontier research with the ",{"id":216,"funder":7,"programme":8,"title":217,"piName":10,"institution":218,"country":193,"year":13,"amount":219,"abstract":220},"cordis-european-research-council-award-853404","Variational approach to the regularity of the free boundaries","UNIVERSITA DI PISA","€1,330,325","The focus of this project is the regularity theory of free boundary problems. This is a fascinating topic, which combines methods from Analysis and Geometry, and has numerous applications to a large variety of problems in Physics, Engineering and Economy, which involve partial differential equations on domains whose boundary is free, that is, it is not a priori known. Typical examples are the Stefan problem, describing the evolution of a block of melting ice, and the American stock options. Sinc",{"id":222,"funder":7,"programme":8,"title":223,"piName":10,"institution":224,"country":225,"year":13,"amount":226,"abstract":227},"cordis-european-research-council-award-851143","Intracellular lasers: Coupling of optical resonances with biological processes","INSTITUT JOZEF STEFAN","SI","€1,492,090","Recently, micro-sized lasers have been integrated into biological systems including cells and tissues. Currently the most frequently used techniques to study complex processes in live cells employ fluorescent probes. However, fluorescent probes have several disadvantages including photobleaching, sensitivity to environmental factors, potential phototoxicity and broad emission spectrum, which limits their sensitivity, multiplexing ability and imaging capabilities in biological tissues. The transi",{"id":229,"funder":7,"programme":8,"title":230,"piName":10,"institution":231,"country":52,"year":13,"amount":232,"abstract":233},"cordis-european-research-council-award-850764","Atomic-Scale Motion Picture: Taming Cluster Catalysts at the Abyss of Meta-Stability","TECHNISCHE UNIVERSITAET MUENCHEN","€1,499,375","From fine chemical synthesis over combustion control to electrode design   the majority of chemical reactions rely on catalysts to improve energy and material efficiency. Yet, the atomic-scale processes underlying a catalytic reaction at elevated pressures are far less well-understood than one might expect. Indeed, the successful optimization of industrial catalysts is typically achieved by trial and error. If we precisely understood the correlation between catalyst dynamics and activity, we cou",{"id":235,"funder":7,"programme":8,"title":236,"piName":10,"institution":231,"country":52,"year":13,"amount":237,"abstract":238},"cordis-european-research-council-award-852845","Sterile neutrino search in tritium beta decay","€1,733,750","What is the nature of Dark Matter? What is the origin of the neutrino mass? These are two of the most compelling mysteries, physics is facing today. Despite its tremendous success, the Standard Model of Particle Physics does not provide an answer to these questions. Since the Nobel-prize awarded discovery of the neutrino oscillations, which proofs that neutrinos have a mass, the existence of right-handed partners to the known left-handed neutrinos is a basic assumption. This minimal extension of",{"id":240,"funder":7,"programme":8,"title":241,"piName":10,"institution":231,"country":52,"year":13,"amount":242,"abstract":243},"cordis-european-research-council-award-852187","Synthetic Active Droplets Inspired by Life","€1,491,350","Active droplets are made of molecular building blocks that are activated and deactivated by a chemical reaction cycle. In the activation, a precursor is converted into a building block for droplets driven by the consumption of fuel. In the deactivation, the building blocks react back to the precursor. In other words, active droplets emerge when fuel is supplied, but decay when fuel is depleted. Theoretical studies show active droplets all evolve to the same size. Another work predicts that the d",{"id":245,"funder":7,"programme":8,"title":246,"piName":10,"institution":231,"country":52,"year":13,"amount":247,"abstract":248},"cordis-european-research-council-award-948049","Single-cell nuclear magnetic resonance spectroscopy with diamond quantum sensors","€2,120,290","Single-cell events are often responsible for biological phenomena, such as drug resistance, cell development or tumorigenesis. Studies on cellular populations mask such characteristics and make single-cell technologies essential for understanding cell biology. However, one of the major analytical tools with the advantage of high molecular specificity and non-invasiveness, nuclear magnetic resonance (NMR) spectroscopy, has been limited in its application to single-cell studies due to its intrinsi",{"id":250,"funder":7,"programme":8,"title":251,"piName":10,"institution":231,"country":52,"year":13,"amount":252,"abstract":253},"cordis-european-research-council-award-851161","Constrained Quantum Dynamics","€1,498,750","Recently, tremendous progress has been made in exploring non-equilibrium dynamics of correlated quantum matter. The project ConsQuanDyn investigates the relaxation dynamics and the dynamical quantum phases, induced by parameter quenches or by periodic drive, in quantum matter with dynamically constrained excitations. Such constrained systems, which can be dual to gauge theories and host exotic topological order, have been recently realized in Rydberg quantum simulators and have a long tradition ",{"id":255,"funder":7,"programme":8,"title":256,"piName":10,"institution":11,"country":12,"year":13,"amount":257,"abstract":258},"cordis-european-research-council-award-853356","Anthropogenic Heathlands: The Social Organization of Past Grazing Landscapes","€1,499,457","In a time of accelerating human-caused ecological catastrophe, questions of organizational resilience have become extremely timely. In bringing the archaeological perspective of a 4200-year timespan, ANTHEA seeks to to radically alter our knowledge of resilient forms of self-organisation in past land-use regimes and human-nature entanglements. Based on seven case study areas, ANTHEA will show how collaborative institutions of common land use were organized in the North European heathland regimes",{"id":260,"funder":7,"programme":8,"title":261,"piName":10,"institution":11,"country":12,"year":13,"amount":262,"abstract":263},"cordis-european-research-council-award-849841","Resource efficient bio-chemical production and waste treatment","€1,494,622","The REBOOT project will create a disruptive wet waste valorisation technology where valuable resources are re-used rather than disposed of while tackling two urgent environmental challenges: nutrient circularity and climate change. Wastewater treatment sludge and manure treatment technologies are currently not satisfactory and there is no solution to efficiently re-use the resources it contains: phosphorous and carbon.The aim of REBOOT is to completely recover phosphorous from wastes while gener",{"id":265,"funder":7,"programme":8,"title":266,"piName":10,"institution":267,"country":52,"year":13,"amount":268,"abstract":269},"cordis-european-research-council-award-945719","Human-Centric Machine Learning","MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV","€1,495,000","With the advent of mass-scale digitization of information and virtually limitless computational power, an increasing number of social, information and cyber-physical systems evaluate, support or even replace human decisions using machine learning models and algorithms.  Machine learning models and algorithms have been traditionally designed to take decisions autonomously, without human intervention, on the basis of passively collected data. However, in most social, information and cyber-physical",{"id":271,"funder":7,"programme":8,"title":272,"piName":10,"institution":273,"country":274,"year":13,"amount":275,"abstract":276},"cordis-european-research-council-award-848698","Global Lagrangian Cloud Dynamics","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","CH","€1,493,343","This project will address fundamental gaps in our understanding of how clouds form, how they interact with the atmospheric flow and how they need to be simulated in weather and climate models. Our inability to improve the representation of clouds and their interactions with the atmospheric flow is the leading cause of the high level of uncertainty associated with projections of future changes in storm tracks, precipitation bands and weather extremes. The representation of clouds in models is poo",{"id":278,"funder":7,"programme":8,"title":279,"piName":10,"institution":280,"country":281,"year":13,"amount":282,"abstract":283},"cordis-european-research-council-award-949364","Communications at the Synapse - a Near Atomic Resolution View into Cell-Cell Communication in the CNS","WEIZMANN INSTITUTE OF SCIENCE","IL","€1,499,885","Synapses are intercellular junctions specialized for coordinated cell-cell communication throughout the nervous system. They are organized by cell-adhesion molecules (CAMs) that bi-directionally orchestrate neuronal communication. Latrophilins (LPHNs) are a unique sub-family of CAMs that play critical roles in structuring the synaptic architecture through multifaceted interactions with a large variety of synaptic partners. Mutations in LPHN have been associated with neurodevelopmental and neurop",{"id":285,"funder":7,"programme":8,"title":286,"piName":10,"institution":287,"country":12,"year":13,"amount":288,"abstract":289},"cordis-european-research-council-award-947757","Trees outside forests in global drylands","KOBENHAVNS UNIVERSITET","€1,711,467","Drylands cover approximately 65 million km² of the Earth’s land surface but their tree and shrub cover is a major unknown in terrestrial research. This is because a large proportion of dryland trees grow isolated without canopy closure and most scientific and non-scientific interest is devoted to forests, while the density and size of trees outside of forests is not well documented. However, these non-forest trees play a crucial role for biodiversity and provide ecosystem services such as carbon",{"id":291,"funder":7,"programme":8,"title":292,"piName":10,"institution":293,"country":52,"year":13,"amount":294,"abstract":295},"cordis-european-research-council-award-851280","Dynamical Band Structure Engineering","UNIVERSITAET REGENSBURG","€1,863,750","The band structure of solids is mainly determined by the orbital overlap between neighboring atoms. Therefore, electronic properties are commonly controlled via the chemical composition that determines the relevant structural parameters such as bond angles and lengths. DANCE will use a radically different approach where control of the effective orbital overlap is achieved by periodic modulation of the solid with strong mid-infrared and terahertz light fields. In this way, DANCE will control the ",{"id":297,"funder":7,"programme":8,"title":298,"piName":10,"institution":299,"country":64,"year":13,"amount":300,"abstract":301},"cordis-european-research-council-award-853560","Moving around without a brain: Evolution of basal cognition in single-celled organisms","THE UNIVERSITY OF EXETER","€1,950,430","Even unicellular organisms have a sense of self -- that basal recognition of where their own membranous boundaries end, and where the extracellular environment in which they inhabit begins. Yet unlike the cells in your body, these primitive lifeforms can reproduce, and exist autonomously, most importantly, they can respond to stimuli, and change their behaviour accordingly. Responsive self-movement is a defining characteristic of life, which for simple organisms is essential to enable to them to",{"id":303,"funder":7,"programme":8,"title":304,"piName":10,"institution":305,"country":100,"year":13,"amount":306,"abstract":307},"cordis-european-research-council-award-850159","Experimenting with Circular Service Business Models","UNIVERSITEIT MAASTRICHT","€1,499,915","With increasing pressures on resources and the climate it is clear that a new business paradigm is needed. The Circular Economy has been heralded as a driver for sustainability and competitiveness. In contrast to the current linear economy, materials are kept at their highest utility at all times. Despite great policy, business and academic interest, knowledge on how to move to a Circular Economy is lacking. CIRCULAR X addresses a new and urgent issue in sustainability research: experimentation ",{"id":309,"funder":7,"programme":8,"title":310,"piName":10,"institution":311,"country":20,"year":13,"amount":312,"abstract":313},"cordis-european-research-council-award-851740","Exotic superconducting CIrcuits to Probe and protect quantum States of light and mattEr","ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS","€1,498,875","Quantum systems can occupy peculiar states, such as superposition or entangled states. These states are intrinsically fragile and eventually get wiped out by inevitable interactions with the environment. Protecting quantum states against decoherence is a formidable and fundamental problem in physics, which is pivotal for the future of quantum computing. The theory of quantum error correction provides a solution, but its current envisioned implementations require daunting resources: a single bit ",{"id":315,"funder":7,"programme":8,"title":316,"piName":10,"institution":317,"country":318,"year":13,"amount":252,"abstract":319},"cordis-european-research-council-award-946192","Investigating the Human Mycobolome through Uniting Large-scale Epidemiological and Mechanistic Poly-omic Designs","UNIVERSITEIT GENT","BE","Mycotoxins, toxic fungal secondary metabolites, known to be the most hazardous of all food contaminants in terms of chronic toxicity, have the potential to contribute to a diversity of adverse health effects in humans, and are unfortunately ubiquitously present in our daily diet. Chronic low-dose intake of multiple mycotoxins are hypothesized to be associated with an increased risk of developing human renal, colorectal and hepatocellular carcinomas. HUMYCO refers to a unique, holistic & multi(cr",{"id":321,"funder":7,"programme":8,"title":322,"piName":10,"institution":323,"country":281,"year":13,"amount":324,"abstract":325},"cordis-european-research-council-award-949499","Randomness Extractors: Constructions and Applications","TEL AVIV UNIVERSITY","€1,493,750","Randomness extractors are central in theoretical computer science and have a huge impact in complexity theory, error correcting codes, and cryptography to name a few.  Informally, a randomness extractor is an algorithm that purifies the randomness of an imperfect random source by extracting from it a sequence of uniform and independent random bits.  The myriad of applications make randomness extractor theory a vibrant and exciting research field with a major impact.  Over the last few years, the",{"id":327,"funder":7,"programme":8,"title":328,"piName":10,"institution":329,"country":52,"year":13,"amount":330,"abstract":331},"cordis-european-research-council-award-851485","Regional disparities in cause-specific mortality in Europe: the role of local context and national health policies","BUNDESINSTITUT FUR BEVOLKERUNGSFORSCHUNG","€1,423,858","Current socio-epidemiologic theories often perceive mortality (health) inequalities as a given and largely ignore the fundamental questions concerning their origin. Furthermore, the majority of prior studies on international differences in mortality have focused on cross-country differences without taking into account substantial regional variation within national populations. REDIM goes beyond the state of the art through performing a large-scale systematic investigation of the reasons for pers",{"id":333,"funder":7,"programme":8,"title":334,"piName":10,"institution":335,"country":281,"year":13,"amount":336,"abstract":337},"cordis-european-research-council-award-948716","All-Optical Dissection of Hippocampal Circuits Using Voltage Imaging","THE HEBREW UNIVERSITY OF JERUSALEM","€1,486,797","The hippocampus is critical for the storage of episodic memories and has been extensively studied on its role in spatial memory. The hippocampus is also a central model for in vitro studies on the molecular, cellular and microcircuit basis for learning and memory. I propose to use a new technology that I developed to record and manipulate the membrane potential of multiple neurons, simultaneously, in behaving animals to reveal the mechanisms by which hippocampal circuits process spatial informat",{"id":339,"funder":7,"programme":8,"title":340,"piName":10,"institution":341,"country":342,"year":13,"amount":181,"abstract":343},"cordis-european-research-council-award-850622","Resilience and Trigger Factors in Cardiac Arrhythmia: Risk Stratification and Drug Design","LINKOPINGS UNIVERSITET","SE","Up to 30% of individuals with inherited cardiac arrhythmias such as Long QT syndrome are not protected from sudden cardiac death despite state-of-the-art treatment. A major hurdle for effective risk stratification and treatment of inherited cardiac arrhythmias is the poor correlation between genetic variant and clinical manifestations. Affected individuals, who harbour the same arrhythmia-causative mutation, paradoxically display a spectrum of clinical phenotypes ranging from a lifelong asymptom",{"id":345,"funder":7,"programme":8,"title":346,"piName":10,"institution":347,"country":212,"year":13,"amount":81,"abstract":348},"cordis-european-research-council-award-853514","Land, Property and Spatial Justice in International Law","UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN","This project will scrutinize the concept, definition and interpretation of property rights in international law as they relate to land. It will not only examine the international human rights, environmental and cultural heritage law frameworks, but also specific areas of international economic law, including investment, that converge and diverge with spatial justice in the realm of land-based projects and policies. Lastly, the project will also include a strong conceptual component, by ascertain",{"id":350,"funder":7,"programme":8,"title":351,"piName":10,"institution":352,"country":93,"year":13,"amount":353,"abstract":354},"cordis-european-research-council-award-850450","Repurposing clinically approved antibacterial drugs for treponematoses therapy","FUNDACION  FLS DE  LUCHA CONTRA ELSIDA LAS ENFERMEDADES INFECCIOSASY LA  PROMOCION DE  LA SALUD Y LACIENCIA","€1,498,790","Current therapeutic options for human treponematoses, syphilis and yaws, are, broadly speaking, restricted to one antibiotic: injectable penicillin. The drug susceptibility profile of Treponema pallidum (T.p) is unknown because the microorganism could not be grown in culture. Treatment failure after penicillin has been related to syphilis bacteria that survive in the central nervous system (CNS) and the potential of strains to acquire resistance to penicillin has recently been recognized. Yaws c",{"id":356,"funder":7,"programme":8,"title":357,"piName":10,"institution":267,"country":52,"year":13,"amount":81,"abstract":358},"cordis-european-research-council-award-851523","Experimental Epidemiology in Ant Societies","The risks and impact of disease are exacerbated in social organisms, which live in dense groups wherein pathogens can rapidly propagate. Theoretical epidemiology predicts that disease dynamics will depend in large part on a group's social interaction network, but empirical data are scarce. Experimental epidemiology is currently hampered by a lack of study systems that would enable a rigorous investigation of the causal link between network structure and disease transmission. I will tackle this q",{"id":360,"funder":7,"programme":8,"title":361,"piName":10,"institution":362,"country":52,"year":13,"amount":252,"abstract":363},"cordis-european-research-council-award-850496","Bismuth Redox Catalysis for Sustainable Organic Synthesis","MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG","Homogeneous catalysis based on transition metals has become an indispensable strategy in the development of efficient methodologies for organic synthesis, finding application in a wide variety of processes across the chemical sciences. Inspired by the wealth of reactivity in this area, we present a proposal that departs from transition metal catalysis and aims at unlocking the potential of bismuth (Bi) as a sustainable catalyst, unravelling novel and unknown catalytic redox processes for organic",{"id":365,"funder":7,"programme":8,"title":366,"piName":10,"institution":367,"country":64,"year":13,"amount":368,"abstract":369},"cordis-european-research-council-award-948895","The Metallization Conditions of Element One","THE UNIVERSITY OF EDINBURGH","€1,499,365","Element number one, hydrogen, is the simplest and most abundant element in the universe. The relative abundance is reflected in the gas giant Jupiter, where under extreme pressures and temperatures, hydrogen exists in a dense metallic fluid state. In 1935, it was predicted that such a metallic state could also be realised at considerably lower temperatures, whereby the quantum molecular solid would dissociate under compression into an atomic metal. With the development of modern quantum mechanic",{"id":371,"funder":7,"programme":8,"title":372,"piName":10,"institution":373,"country":64,"year":13,"amount":374,"abstract":375},"cordis-european-research-council-award-851504","Chemical Control of Vibronic Coupling for Magnetic Materials","THE UNIVERSITY OF MANCHESTER","€1,945,994","The applicant has an outstanding track record and a growing international reputation as an independent early-career researcher. This StG proposal combines computational and experimental themes in an integrated project, and will open a new research field of vibronic control.Coupling of molecular vibrations to electronic states (vibronic coupling) is a fundamental process that affects the outcome of chemical reactions and physical processes, but it is remarkable how little we know about it. For ex",{"id":377,"funder":7,"programme":8,"title":378,"piName":10,"institution":305,"country":100,"year":13,"amount":379,"abstract":380},"cordis-european-research-council-award-804851","Trafficking transformations: objects as agents in transnational criminal networks","€1,498,901","The Trafficking Transformations Project will use an innovative, multidisciplinary, object-centred framework to investigate the physical and contextual changes that illicit criminogenic collectables undergo during the trafficking process in three transnational criminal markets: antiquities, rare wildlife, and fossils. It will explore the socio-economic effects of the trafficked objects on participants in international criminal networks. It will transform organised crime research by shifting the f",{"id":382,"funder":7,"programme":8,"title":383,"piName":10,"institution":384,"country":281,"year":13,"amount":385,"abstract":386},"cordis-european-research-council-award-853393","Attosecond space-time imaging of coherent quantum dynamics","TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY","€1,690,323","Coherence is a fundamental property of quantum mechanics, characterizing phase correlations of light or matter waves. It is at the heart of many physical phenomena, such as the creation of electron-hole pairs in the photovoltaic effect or the fast migration of electronic charge within a molecule. In order to study coherent electron dynamics, extremely high spatial and temporal resolving power is required, which is highly challenging. Well-established imaging methods like scanning tunneling micro",{"id":388,"funder":7,"programme":8,"title":389,"piName":10,"institution":390,"country":20,"year":13,"amount":391,"abstract":392},"cordis-european-research-council-award-802658","Unveiling the role of X-rays in protoplanetary disks via laboratory astrophysics","UNIVERSITE PARIS-SACLAY","€1,499,876","The arrival of ALMA and JWST could revolutionize our understanding of planet formation from the observations of protoplanetary disks. But in order to interpret such observations, better models fed by robust laboratory data are urgently needed. However, laboratory experiments designed to study cosmic matter have mostly focused on the first stages of stellar evolution, where molecular clouds are irradiated by ultraviolet (UV) photons from OB stars. The subsequent protoplanetary stage, where young ",{"id":394,"funder":7,"programme":8,"title":395,"piName":10,"institution":154,"country":64,"year":13,"amount":396,"abstract":397},"cordis-european-research-council-award-851145","Foundations of Animal Sentience","€1,499,864","The goal of ASENT is to construct solid conceptual and methodological foundations for the science of animal sentience.The term sentience refers to an animal’s subjective experience of the world and of its own body. In recent years, an interdisciplinary community of animal sentience researchers, drawn from neuroscience, comparative psychology, evolutionary biology, animal welfare science and philosophy, has begun to emerge. However, the field is characterized by foundational controversy over the ",{"id":399,"funder":7,"programme":8,"title":400,"piName":10,"institution":19,"country":20,"year":13,"amount":401,"abstract":402},"cordis-european-research-council-award-852161","A Missing Key Property in Atmospheric AeRosol ChEmistry:  the Laplace Pressure","€1,994,813","Fine aerosol particles are ubiquitous in the atmosphere and have important impacts on climate change and air quality. Organic compounds represent the largest mass fraction of fine particulate matter and their formation is believed to occur through the condensation of oxygenated volatile organic compounds. However, a fundamental physicochemical property of atmospheric aerosols – the Laplace pressure – has never been studied. This “missing” property is expected to have major implications for atmos",{"id":404,"funder":7,"programme":8,"title":405,"piName":10,"institution":186,"country":64,"year":13,"amount":406,"abstract":407},"cordis-european-research-council-award-851667","A DNA NANOtechology toolkit for artificial CELL design","€1,497,477","Bottom-up synthetic biology aims to artificially replicate the emerging behaviours of cellular life but struggles to do so without relying on poorly controllable machinery borrowed from biological cells.DNA nanotechnology enables ab-initio design of nanoscale objects with fully programmable structure and dynamic response, making them ideal to mimic the complex functionalities of biological machinery in a truly bottom-up fashion.NANOCELL will establish a fully modular and integrated platform that",{"id":409,"funder":7,"programme":8,"title":410,"piName":10,"institution":19,"country":20,"year":13,"amount":312,"abstract":411},"cordis-european-research-council-award-851560","Learning from social scents: from territory to identity","Olfaction is a central sensory modality in most Mammals as it supports vital functions such as feeding, mating and social interactions. Social chemosignals (olfactory cues from urine or body secretions) are efficient communication cues carrying important information such as territory ownership, resources’ locations and identity. Remembering such information is a key advantage for individuals allowing them to adapt their behaviors based on prior experience. However, how social chemosignals are pr",{"id":413,"funder":7,"programme":8,"title":414,"piName":10,"institution":415,"country":64,"year":13,"amount":416,"abstract":417},"cordis-european-research-council-award-850624","Design and engineering of porous nitride-based materials as a platform for CO2 photoreduction","IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE","€1,498,934","CONTEXT: Reshaping our energy portfolio considering the sustainability of global energy resources is central to the European Energy Roadmap 2050. Hence, researchers need to identify efficient routes towards solar fuels production. Unlike H2 evolution, CO2 photoreduction has been poorly studied. Given the scope for CO2 utilisation in a carbon-constrained future, there is an exciting opportunity to devote targeted research towards CO2 photoreduction. Photocatalysis is one route towards CO2 reducti",{"id":419,"funder":7,"programme":8,"title":420,"piName":10,"institution":421,"country":100,"year":13,"amount":422,"abstract":423},"cordis-european-research-council-award-852386","Information Encoding in Quantum Gravity and the Black Hole Information Paradox","UNIVERSITEIT VAN AMSTERDAM","€1,497,340","LIGO’s detection of merging black holes was a spectacular confirmation of general relativity (GR), yet it remains an open question whether black holes obey the same rules of quantum mechanics (QM) as all other known objects in the universe. Black holes are objects in GR which are known to have a vast entropy, but when QM is applied they evaporate by emission of Hawking radiation which carries no information about their microstates - this is the black hole information loss paradox which has evade",{"id":425,"funder":7,"programme":8,"title":426,"piName":10,"institution":415,"country":64,"year":13,"amount":427,"abstract":428},"cordis-european-research-council-award-853022","Planet Evaporation as a Window into Exoplanetary Origins","€1,464,320","Modern astronomy has truly entered the exoplanet era. Although our knowledge of what planet formation produces has grown immensely thanks to observational advances, our actual understanding of the physical processes that give rise to planets and planetary systems is limited. We now know most stars are unlike our own Sun, in that they host planets which orbit around their star with periods of months or shorter, yet many have volatile rich atmospheres. These planets must result from a dominant (if",{"id":430,"funder":7,"programme":8,"title":431,"piName":10,"institution":415,"country":64,"year":13,"amount":432,"abstract":433},"cordis-european-research-council-award-851705","Behavioural biomechanics of insect herbivory - a case study on leaf-cutter ants","€1,998,764","Insect herbivores are a dominant element in terrestrial ecosystems, and pose a continuing threat to global food security. However, little is known about a key determinant of insect herbivore success: the mechanics of plant-feeding. MechAnt proposes to transform our understanding of insect-plant relations by providing a rigorous biomechanical investigation into how insects cut leaves, using the major ecosystem engineers and principal insect pest of the New World, the leaf-cutter ants, as a model ",{"id":435,"funder":7,"programme":8,"title":436,"piName":10,"institution":19,"country":20,"year":13,"amount":437,"abstract":438},"cordis-european-research-council-award-850996","Motivated Reading of Evidence","€1,234,878","Economists have distinguished for long soft and hard information with the understanding that cheap talk is more prone to subjective interpretation than hard evidence. In fact, any piece of evidence carries some of the true underlying information that agents are usually assumed to be willing and able to access. For various reasons, agents may however prefer to avoid disturbing truths or maintain wrong but encouraging beliefs. In MOREV, I propose to study motivated reading of evidence, that is, st",{"id":440,"funder":7,"programme":8,"title":441,"piName":10,"institution":19,"country":20,"year":13,"amount":442,"abstract":443},"cordis-european-research-council-award-853282","Probing topological valley currents by angular layer alignment in van der Waals heterostructures","€1,499,543","The relative angular alignment between the stacked 2D layers of a van der Waals (vdW) heterostructure can dramatically alter its fundamental properties. A striking example is the recent observation of strongly correlated states and intrinsic superconductivity in twisted bilayer graphene. Another remarkable effect of angular layer alignment predicted for certain vdW heterostructures is the emergence of phases of matter with non-trivial topological properties, where charge carriers flow without di",{"id":445,"funder":7,"programme":8,"title":446,"piName":10,"institution":273,"country":274,"year":13,"amount":447,"abstract":448},"cordis-european-research-council-award-851701","Homeomorphisms in symplectic topology and dynamics","€1,340,472","The subject of this proposal is the field of continuous symplectic topology. This is an area of symplectic topology which defines and studies continuous analogues of smooth symplectic objects such as symplectic and Hamiltonian homeomorphisms and asks questions about persistence of various symplectic phenomena under uniform limits and perturbations.Our aim is to explore, and further develop, continuous symplectic topology from two different perspectives: The first is a symplectic topological pers",{"id":450,"funder":7,"programme":8,"title":451,"piName":10,"institution":19,"country":20,"year":13,"amount":452,"abstract":453},"cordis-european-research-council-award-852573","Eight millennia of changes in domestic plants and animals: understanding local adaptation under socio-economic and climatic fluctuations","€1,447,800","The domestication of plants and animals marks a major transition in human history and is a key element in the development of modern societies. Local and traditional domestic breeds and varieties are the result of millennia of selection of landraces by farmers. However, we are now experiencing a major crisis with a drastic loss in the diversity of food production systems and the progressive disappearance of traditional practices. The local knowledge and culture of farmers are under threat, as wel",{"id":455,"funder":7,"programme":8,"title":456,"piName":10,"institution":19,"country":20,"year":13,"amount":457,"abstract":458},"cordis-european-research-council-award-850539","Formal Models of Social Meaning and Identity Construction through Language","€1,415,974","One of the most powerful ideas of the past quarter century is that our personal and social identities and their various components (gender, age, class etc.) are not natural properties, but are socially constructed through the combination of our actions and others' interpretations of them. Research in sociolinguistics has shown that language is critical to this process, and our interlocutors take into account not only what we say but also how we say it. For example, studies have shown that speake",{"id":460,"funder":7,"programme":8,"title":461,"piName":10,"institution":19,"country":20,"year":13,"amount":462,"abstract":463},"cordis-european-research-council-award-852640","Dominating redox mechanisms in iron-mediated C-C bond formations: reactivity, new paradigms and applications","€1,398,620","Due to the ubiquity of the C-C bond in diverse areas such as pharmaceuticals, agrochemicals or materials, development of atom-economical and efficient methods ensuring its formation is an active research field. This field witnessed incredible breakthroughs during the last decades, especially thanks to organometallic catalysis applied to cross-coupling or C-H activation methods. However, the most efficient C-C bond formation reactions rely on noble-metal catalysts, which lead to economic and toxi",{"id":465,"funder":7,"programme":8,"title":466,"piName":10,"institution":19,"country":20,"year":13,"amount":467,"abstract":468},"cordis-european-research-council-award-850820","Molecular Structure and Engineering of Synaptic Organizer Proteins in Health and Disease","€1,499,903","Synapses are the specialized cellular junctions that form the basic units of communication between neuronal cells. Given the variety of network-dependent functions that synapses need to support, a fundamental question is how their properties are specified at the molecular level. Membrane-anchored and soluble “synaptic organizer proteins” form adhesive interactions that mediate synapse formation and differentiation. However, a structural and mechanistic understanding of how they recruit and organ",{"id":470,"funder":7,"programme":8,"title":471,"piName":10,"institution":19,"country":20,"year":13,"amount":472,"abstract":473},"cordis-european-research-council-award-851866","Fast Monte Carlo integration with repulsive processes","€1,489,000","Expensive computer simulations have become routine in the experimental sciences. Astrophysicists design complex models of the evolution of galaxies, biologists develop intricate models of cells, ecologists model the dynamics of ecosystems at a world scale. A single evaluation of such complex models takes minutes or hours on today's hardware. On the other hand, fitting these models to data can require millions of serial evaluations. Monte Carlo methods, for example, are ubiquitous in statistical ",{"id":475,"funder":7,"programme":8,"title":476,"piName":10,"institution":19,"country":20,"year":13,"amount":477,"abstract":478},"cordis-european-research-council-award-805098","Beyond Eureka: The Foundations of Japan's Industrialization, 1800-1885","€1,373,500","Beyond Eureka seeks to challenge current understanding of how Japan became a global industrial power along with the model of how innovation takes place. Japan was the first Asian nation to industrialize and in a space of several decades went from a relatively isolated agrarian economy to an industrialized nation. The key assumption of this project is that a grasp of the salient features of the technological landscape during the pivotal period between 1800 and 1885 is an important tool for unders",{"id":480,"funder":7,"programme":8,"title":481,"piName":10,"institution":482,"country":483,"year":13,"amount":484,"abstract":485},"cordis-european-research-council-award-852816","Social Resilience, Gendered Dynamics, and Local Peace in Protracted Conflicts","UNIVERSITETET I OSLO","NO","€1,499,982","How can ‘resilient communities’ remain resilient in protracted conflicts and contribute to sustainable peace rather than to increased vulnerability to renewed conflict? How do local conflicts link to national conflicts and what are the implications for peacebuilding? What are the gender dimensions of social resilience? Is resilience always ‘a good thing’ or may it impede conflict resolution? This project pioneers an interdisciplinary research agenda into resilience building. The need for a great",{"id":487,"funder":7,"programme":8,"title":488,"piName":10,"institution":482,"country":483,"year":13,"amount":489,"abstract":490},"cordis-european-research-council-award-851132","Between Sea and City: Ethnographic explorations of infrastructure, work, and place around leading urban container ports","€1,499,950","How to study the turbulent transitions and risky mobilities of global capitalism today? An illuminating, but often overlooked site that lends itself to explorations into the changing nature of our economic system can be found at the interface between sea and city, i.e. at the port. Container ports have often been pushed to the edges of the urban spaces that they used to be centrally located in. A study on the city\u002Fsea-nexus will illuminate the dynamics behind the ways in which the center of glob",{"id":492,"funder":7,"programme":8,"title":493,"piName":10,"institution":482,"country":483,"year":13,"amount":494,"abstract":495},"cordis-european-research-council-award-852190","CoFutures: Pathways to Possible Presents","€1,319,219","This project investigates future fictions from five distinct traditions: Afrofuturism, Sinofuturism, Arab\u002FGulf-futurism, Latin@futurism, and Indofuturism. All these fictions respond to the burning issues of the present, the transnational discourses of demographic change, climate change, and technological change, but they imagine different, localized ways of engaging with these transnational discourses.Research QuestionsWhat contributions can contemporary future fictions make to our understanding",{"id":497,"funder":7,"programme":8,"title":498,"piName":10,"institution":482,"country":483,"year":13,"amount":81,"abstract":499},"cordis-european-research-council-award-853211","The Developing Communicator: Pragmatics, Sense Conventions and Non-Literal Uses of Language","Children are born communicators. A growing body of developmental evidence suggests that the cognitive abilities enabling the expression and comprehension of communicative intentions – so-called pragmatic abilities – which underlie language use and understanding, develop early. However, a puzzling feature of pragmatic development is young children’s difficulties with non-literal uses of language (e.g., “I love you so much I could eat you up!”). How can children be early experts at a range of prag",{"id":501,"funder":7,"programme":8,"title":502,"piName":10,"institution":503,"country":212,"year":13,"amount":504,"abstract":505},"cordis-european-research-council-award-851411","Arabic Poetry in the Cairo Genizah","THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN","€1,456,246","Poetry enjoys a special place in Arabic culture and literature. For centuries, Arabs of all faiths have considered poetry a key source for knowledge, intellectuality and wisdom. In the pre-Islamic era, poetry was considered as ‘the Arab knowledge’ and ‘the Arab cultural archive’, in which the social and cultural history, language, arts, music, religious and Arab’s human experience were stored and preserved. Being a part of Arabic culture, Jews of Arab lands equally enjoyed writing and reading po",{"id":507,"funder":7,"programme":8,"title":508,"piName":10,"institution":503,"country":212,"year":13,"amount":81,"abstract":509},"cordis-european-research-council-award-804994","Admixture accelerated adaptation: signals from modern, ancient and archaic DNA.","With the advent of new sequencing technologies, population geneticists now have access to more data than ever before. We have access to thousands of human genomes from a diverse set of populations around the globe, and, thanks to advances in DNA extraction and library preparation, we now are beginning to have access to ancient DNA sequence data. These data have greatly improved our knowledge of human history, human adaptation to different environments and human disease. Genome-wide studies have ",{"id":511,"funder":7,"programme":8,"title":512,"piName":10,"institution":513,"country":12,"year":13,"amount":514,"abstract":515},"cordis-european-research-council-award-852123","Transforming Norms Research through Practices: Weaponised Artificial Intelligence, Norms, and Order","SYDDANSK UNIVERSITET","€1,499,759","Weapons systems with an increasing number of autonomous features are emerging as revolutionary technologies of war. In particular, this concerns systems with autonomy in their critical functions that relate to selecting and engaging targets without human input. This weaponisation of Artificial Intelligence (AI) signals the looming absence of meaningful human control in warfare, which has become a central focus of the debate on autonomous weapons systems (AWS). Here, states either seek to introdu",{"id":517,"funder":7,"programme":8,"title":518,"piName":10,"institution":519,"country":100,"year":13,"amount":81,"abstract":520},"cordis-european-research-council-award-852115","Enhanced Mass Transport in Electrochemical Systems for Renewable Fuels and Clean Water","TECHNISCHE UNIVERSITEIT DELFT","To meet the growing demand for green energy carriers and clean water for the next decades, we can use the increasing supply of harvested solar and wind energy to synthesize fuels (hydrogen, syngas, ammonia, etc.) and clean water via electrochemical methods. Electrochemical methods have the advantage of single-step, energy-efficient and low-temperature conversion of chemicals. However, despite developments in electrocatalysts and system design in the past decade, none of the electrochemical metho",{"id":522,"funder":7,"programme":8,"title":523,"piName":10,"institution":524,"country":20,"year":13,"amount":525,"abstract":526},"cordis-european-research-council-award-853507","Scattering Strings and Other Things: A Modern Approach to Quantum Gravity and the Conformal Bootstrap","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","€1,444,174","What is the space of consistent conformal field theories (CFTs) and of theories of quantum gravity?What are the underlying physical and functional structures of AdS scattering amplitudes and large N CFT correlation functions?Can we construct string and M-theory from precision CFT computations?The conformal bootstrap program continues to generate remarkable insights into the foundational nature of quantum and conformal field theories. In the context of the AdS\u002FCFT Correspondence, these are direct",{"id":528,"funder":7,"programme":8,"title":529,"piName":10,"institution":186,"country":64,"year":13,"amount":530,"abstract":531},"cordis-european-research-council-award-851682","Renormalisation, dynamics, and hyperbolic symmetry","€1,250,043","The objective of this proposal is to develop effective methods for the analysis of classical continuous spin systems, with focus on their stochastic dynamics and on spin systems with hyperbolic symmetry. The latter are related to reinforced random walks and to random operators. In particular, I propose to develop mathematical methods for renormalisation group analysis of such systems. Renormalisation is a central concept in theoretical physics, explaining a vast range of phenomena heuristically.",{"id":533,"funder":7,"programme":8,"title":534,"piName":10,"institution":535,"country":100,"year":13,"amount":81,"abstract":536},"cordis-european-research-council-award-852452","Bacteria-mucin interactions – Shaping intestinal epithelial responses in health and disease","UNIVERSITEIT UTRECHT","The intestinal microbiota consists of beneficial commensal bacteria and pathobionts that cause inflammation. The intestinal mucus layer dictates how specific members of the microbiota affect health and disease. The mucus layer consists of soluble mucins and epithelial transmembrane (TM) mucins that regulate host responses. The molecular mechanisms as to how the intestinal microbiota affect the functions of TM mucins is largely unknown. My recent work shows that TM mucin MUC1 is a key receptor fo",{"id":538,"funder":7,"programme":8,"title":539,"piName":10,"institution":540,"country":483,"year":13,"amount":81,"abstract":541},"cordis-european-research-council-award-850717","Whales, waste and sea walnuts: incorporating human impacts on the marine ecosystem within life cycle impact assessment","NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU","The marine ecosystem covers around 70% of the planet. Today, every single part of this vast ecosystem is affected by at least one anthropogenic driver of change. This fact should cause us to pause and think: such a huge space, yet habitat and species loss are occurring at an unprecedented rate. The marine ecosystem provides us with a wealth of services and has an economic value exceeding 20 trillion US Dollars. In addition, the marine ecosystem is considered crucial for our sustainable future an",{"id":543,"funder":7,"programme":8,"title":544,"piName":10,"institution":545,"country":193,"year":13,"amount":546,"abstract":547},"cordis-european-research-council-award-852012","A synthetic biology approach for T cell exhaustion","FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA","€1,496,250","Synthetic Biology has revolutionised approaches for several scientific, industrial and medical applications. These include the development of immunotherapies based on bioengineered cells, most notably engineering of patients T cells with tumor-targeting receptors, the CAR-T cells. Cell-based immunotherapies have shown remarkable clinical success; yet, long-term benefits are hampered by dysfunction of T cells occurring following antigen chronic exposure, a process known as T cell exhaustion. Curr",{"id":549,"funder":7,"programme":8,"title":550,"piName":10,"institution":373,"country":64,"year":13,"amount":551,"abstract":552},"cordis-european-research-council-award-852642","Precision tests of the Standard Model using Beauty to Charm decays","€1,450,020","The present matter-antimatter asymmetry of the universe cannot be explained by the Standard Model (SM) of particle physics. I propose to look for the presence of new physics beyond the SM in Charge-Parity (CP) asymmetries using beauty mesons decaying to charmed mesons (Beauty2Charm). A unique feature of these decays is that the SM contribution can be precisely measured using relations between ten decay modes all of which can be measured with in a coherent manner at a single experiment: LHCb at t",{"id":554,"funder":7,"programme":8,"title":555,"piName":10,"institution":556,"country":274,"year":13,"amount":557,"abstract":558},"cordis-european-research-council-award-851103","Direct Detection of TeV--PeV Cosmic Rays in Space","UNIVERSITE DE GENEVE","€1,499,097","The DArk Matter Particle Explorer (DAMPE) mission has recently marked a new epoch in astroparticle physics, extending the direct measurements of cosmic ray spectra beyond a TeV with unprecedented energy resolution. With this project, based on my leadership position in DAMPE and its unique data, I propose to fundamentally improve the precision of direct cosmic ray measurements at the highest energies  in the TeVPeV range, using for the first time a state-of-the-art artificial intelligence approac",{"id":560,"funder":7,"programme":8,"title":561,"piName":10,"institution":562,"country":193,"year":13,"amount":563,"abstract":564},"cordis-european-research-council-award-853033","De-industrializing Societies and the Political Consequences","UNIVERSITA DEGLI STUDI DI MILANO","€1,106,528","For decades, deindustrialization has inflicted collateral damage far beyond displaced manufacturing workers by affecting the lives of working-class families and driving formerly industrialized areas into deprivation, generating new political fault lines in society. The aim of this project is to reveal how a person’s individual, family, and local community experiences of manufacturing decline transform the way they participate in politics and their political attitudes over the course of their lif",{"id":566,"funder":7,"programme":8,"title":567,"piName":10,"institution":568,"country":52,"year":13,"amount":569,"abstract":570},"cordis-european-research-council-award-850990","Privacy-preserving Services On The Internet","TECHNISCHE UNIVERSITAT DARMSTADT","€1,499,775","Today, when using services on the Internet, users have to fully entrust a single service provider with their data. Many of these service providers are located outside the EU and there are cases where data has not only been leaked by attacks of outsiders or insiders, but also by governments who built backdoors into software or hardware, or forced service providers to give out sensitive user data. With the new EU General Data Protection Regulation (GDPR) also companies have an obligation to proper",{"id":572,"funder":7,"programme":8,"title":573,"piName":10,"institution":574,"country":575,"year":13,"amount":576,"abstract":577},"cordis-european-research-council-award-851288","Design Principles of Branching Morphogenesis","INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA","AT","€1,452,604","Branching morphogenesis, the process by which branched organs such as the lung, prostate, kidney or mammary gland are generated, is a paradigmatic example of complex developmental processes bridging multiple scales. The mechanisms through which given molecular signals and cellular behaviours give rise to a robust organ structure remains a fundamental and open question, for which theoretical methods are needed. Our experience in modelling cytoskeletal mechanics, stem cell dynamics and branching p",{"id":579,"funder":7,"programme":8,"title":580,"piName":10,"institution":421,"country":100,"year":13,"amount":81,"abstract":581},"cordis-european-research-council-award-851678","Ecosystem response to drought: unravelling the unexplored role of plant-soil feedback","Drought is severely threatening our ecosystems and their functioning: it causes strong shifts in plant community composition that are difficult to revert. Positive feedbacks often underlie these dramatic shifts, but in many ecosystems drought causes fast-growing species to increase. These species are not only vulnerable to drought, but they also suffer negative plant-soil feedback, i.e. they change the soil microbial community in a way that keeps their own abundance in check. Thus, drought-induc",{"id":583,"funder":7,"programme":8,"title":584,"piName":10,"institution":585,"country":100,"year":13,"amount":586,"abstract":587},"cordis-european-research-council-award-853625","From mechanical control to shape-shifting in supramolecular biomaterials to guide stem cell fate","UNIVERSITEIT LEIDEN","€2,000,000","The biochemical and biophysical cues of the stem cell environment that act in a concerted and spatiotemporal manner lead to the formation of the 200 cell types and organs of the human body, but how this precisely occurs remains unclear and it is necessary to guide their production for use in the biomedical area. Standard differentiation protocols in vitro mimic known stages in development by the timed addition of biochemical cues on 2D substrates, however these protocols lack the complexity of t",{"id":589,"funder":7,"programme":8,"title":590,"piName":10,"institution":591,"country":575,"year":13,"amount":592,"abstract":593},"cordis-european-research-council-award-851435","Emergence of high-mass stars in complex fiber systems","UNIVERSITAT WIEN","€1,497,805","High-mass stars drive the physical and chemical evolution of the Universe. However, the origin of these massive objects is largely controversial. Three key questions remain under debate: a) Which physical processes determine the formation of high-mass stars? b) How do these stars get their large masses? c) Do high-mass stars form in a similar way to their low-mass counterparts? Galactic surveys link the origin of high-mass stars to the initial properties of their gas embryos. Using the Atacama L",{"id":595,"funder":7,"programme":8,"title":596,"piName":10,"institution":367,"country":64,"year":13,"amount":597,"abstract":598},"cordis-european-research-council-award-853291","Fundamental physics from the large-scale structure of the Universe","€1,328,066","The last 30 years have been a golden era of cosmological discoveries, which revolutionized our understanding of the physical concepts, which govern our Universe. New discoveries indicate that the beginning of our Universe might have been dominated by the inflaton field, which decayed during the first second of the Universes existence, introducing tiny ripples in the matter distribution, which ultimately sourced later galaxy formation. The future of our Universe is dominated by dark energy, which",{"id":600,"funder":7,"programme":8,"title":601,"piName":10,"institution":585,"country":100,"year":13,"amount":602,"abstract":603},"cordis-european-research-council-award-852334","The Micro-foundations of Debt Crises","€1,499,969","This project takes a new bottom-up approach to understanding the political roots of government debt crises. It proposes that in order to understand why governments borrow excessively and experience crises, we must first understand what citizens are thinking (or not thinking) about debt policy. Citizens’ preferences are the cornerstone of political theories because they inform policymakers’ incentives. Yet, no studies have systematically examined why citizens in some countries are willing to take",{"id":605,"funder":7,"programme":8,"title":606,"piName":10,"institution":384,"country":281,"year":13,"amount":607,"abstract":608},"cordis-european-research-council-award-851780","Enabling Novel Electron-Polariton Physics with Nanophotonic Platforms","€1,662,923","Light-matter interactions are highly limited by strict fundamental rules. The commonly used dipole approximation enforces selection rules that prohibit many electronic transitions due to the mismatch between the wavelength of light and the scale of its emitter (e.g., atom, molecule, quantum dot). This mismatch even prevents access to many other light-matter interactions such as spin-flip transitions and multiphoton spontaneous emission.In the past four years, I have shown theoretically and exper",{"id":610,"funder":7,"programme":8,"title":611,"piName":10,"institution":10,"country":10,"year":13,"amount":81,"abstract":612},"cordis-european-research-council-award-851936","Overcoming cellular barriers to therapeutic RNA delivery using extracellular vesicles","RNA-based therapeutics, including siRNA, miRNA, mRNA and CRISPR\u002FCas9 components, have unprecedented therapeutic potential and hold the promise of treating any disease with a genetic component. However, inefficient delivery into diseased cells hinders their clinical progress. Consequently, there is an urgent need for novel, original approaches to overcome the delivery challenges.Recently, an endogenous RNA transport system has emerged, based on the release and uptake of extracellular vesicles (EV",{"id":614,"funder":7,"programme":8,"title":615,"piName":10,"institution":616,"country":274,"year":13,"amount":617,"abstract":618},"cordis-european-research-council-award-850769","Dissecting hippocampal circuits  for the encoding of early-life memories","UNIVERSITAT BASEL","€1,499,055","The infant brain is a formidable learning machine. But is it able to encode memories of early-life experiences? Since most of us don’t remember what happened during the first years of our lives, for a long time this question has been open to debate. Recent evidence suggests that, even if we cannot recall them, early-life memories are encoded in the developing hippocampus, persist in a silent state into adulthood, and can affect the acquisition of new information later in life. We know very littl",{"id":620,"funder":7,"programme":8,"title":621,"piName":10,"institution":622,"country":193,"year":13,"amount":81,"abstract":623},"cordis-european-research-council-award-853179","Revealing dendritic cell-CD4+ T cell communication by using synthetic biology in vivo","UNIVERSITA DEGLI STUDI DI PADOVA","CD4+ T cells are crucial component of our immune system: they support distinct types of proinflammatory responses key for pathogen clearance, maintain tolerance and suppress harmful inflammation. To perform this multitude of functions, naïve CD4+ T cells first undergo activation through direct contact with dendritic cells (DCs), a highly heterogeneous compartment including several populations of migratory and resident cells. These interactions lead to selection of antigen specific T cell clones,",{"id":625,"funder":7,"programme":8,"title":626,"piName":10,"institution":627,"country":100,"year":13,"amount":628,"abstract":629},"cordis-european-research-council-award-852352","The Emergence of Language in Social Interaction","TILBURG UNIVERSITY- UNIVERSITEIT VAN TILBURG","€1,482,813","During spontaneous sign language genesis, signers naturally come to integrate gestural material into their grammars. Researchers have been able to track this process in two famous cases: Nicaragua and Israel’s Negev desert. This project addresses a third case: Kata Kolok (KK) arose six generations ago due to high incidences of deafness in a Balinese village. ELISA determines what the earliest stages of this language looked like and what mechanism have shaped its emergence.Theories of sign langua",{"id":631,"funder":7,"programme":8,"title":632,"piName":10,"institution":10,"country":10,"year":13,"amount":81,"abstract":633},"cordis-european-research-council-award-853385","Translating Memories: The Eastern European Past in the Global Arena","The proposed project offers a new understanding of transnational memory as a process of translation by focusing on post-Soviet Eastern European attempts to make their local histories of the Second World War and the Socialist regime known globally. It examines these efforts through aesthetic media of memory – literature, film and art – that circulate globally and bring local experiences to global audiences and through the heated public debates that these works of art have provoked in different na",{"id":635,"funder":7,"programme":8,"title":636,"piName":10,"institution":637,"country":52,"year":13,"amount":638,"abstract":639},"cordis-european-research-council-award-852236","Exploring strong correlations in flat bands","UNIVERSITY OF HAMBURG","€1,499,640","One spectacular phenomenon in quantum many-body systems is the emergence of non-local quasiparticles with fractional quantum numbers and anyonic statistics. Of fundamental interest, fractionalization also holds promise for fault-tolerant quantum computation motivating the search for such exotic phases of matter. Signatures of this phenomenon remain sparse and mostly restricted to fractional quantum Hall states, despite being predicted to also occur in other systems such as frustrated quantum mag",{"id":641,"funder":7,"programme":8,"title":642,"piName":10,"institution":643,"country":52,"year":13,"amount":644,"abstract":645},"cordis-european-research-council-award-852796","Exploring the diet-microbiota axis for immunomodulation and organ protection in hypertension","CHARITE - UNIVERSITAETSMEDIZIN BERLIN","€1,497,250","Essential hypertension damages organs such as the kidney, thereby leading to premature death. Beyond elevated blood pressure, hypertension is characterized by a pro-inflammatory immune response ahead of measurable organ damage. Activated immune cells infiltrate the kidney to cause tissue injury. However, inflammation is insufficiently addressed by todays drugs. Current treatments do not include the gut microbiota, its metabolites and the associated lymphoid tissue  the largest immune cell reserv",{"id":647,"funder":7,"programme":8,"title":648,"piName":10,"institution":421,"country":100,"year":13,"amount":649,"abstract":650},"cordis-european-research-council-award-853394","Assessing Legacies of Past Human Activities in Amazonia","€1,481,378","Amazon forests contribute vital ecosystem services, including maintaining biodiversity (>10,000 tree species) and storing large amounts of carbon. Amazonia also features prominently in global climate, carbon, and vegetation models, which assume tropical forests are effectively pristine and that past human disturbance mimicked natural processes. It is now evident that recurrent human disturbance of Amazonia, like fire and deforestation, were significant in some areas. Since those disturbances lik",{"id":652,"funder":7,"programme":8,"title":653,"piName":10,"institution":654,"country":20,"year":13,"amount":81,"abstract":655},"cordis-european-research-council-award-948800","A microbial perspective of major historical events in the Southern Cone of the Americas","INSTITUT PASTEUR","Microbes have played fundamental roles throughout our evolution and history. These roles were not only played by pathogens, but also by the trillions of microorganisms inhabiting our body –the microbiome–, which are essential for homeostasis, physiology, and health. Recent advances in ancient DNA research have made possible to study infectious diseases and human microbiomes from ancient human populations, but this field of research is still at its early stages. For instance, it remains largely u",{"id":657,"funder":7,"programme":8,"title":658,"piName":10,"institution":654,"country":20,"year":13,"amount":81,"abstract":659},"cordis-european-research-council-award-852373","Algorithms and multiplex assays for integrated serological surveillance of malaria and neglected tropical diseases","Malaria and neglected tropical diseases (NTDs) such as lymphatic filariasis, onchocerciasis, trachoma and schistosomiasis affect almost 2 billion people every year. Coordinated targeting of these diseases will aid future control and elimination campaigns, but this will require integrated surveillance strategies. Malaria surveillance is routinely implemented through cross-sectional surveys where blood samples are tested for parasites. A major barrier to routine NTD surveillance is the range of sa",{"id":661,"funder":7,"programme":8,"title":662,"piName":10,"institution":663,"country":64,"year":13,"amount":664,"abstract":665},"cordis-european-research-council-award-852050","Shaken and stirred:  Terahertz electric field control of magnetism","UNIVERSITY OF LANCASTER","€1,495,297","The rapid move to wireless devices and the advent of cloud-based technologies in the 21st century’s digital economy call for denser, faster and more energy efficient data storage. However, the heat produced by modern data centres has already become a serious limitation to further increase their performance. At present, the data industry lacks a solution for this problem, which is expected to contribute greatly to the global warming and energy crisis in the near future.With MAGSHAKE I aim to pave",{"id":667,"funder":7,"programme":8,"title":668,"piName":10,"institution":669,"country":281,"year":13,"amount":81,"abstract":670},"cordis-european-research-council-award-849029","Understanding DSB repair from pathway choice to long term effects and their consequences.","BEN-GURION UNIVERSITY OF THE NEGEV","DNA safekeeping is one of the most important functions of the cell. Since DNA damage occurs in the context of chromatin, it affects both the DNA itself, but also the epigenetic landscape. While the repair mechanism of the DNA has been extensively studied, questions abound regarding the restoration of the epigenetic landscape, and the long-term effects that damage leaves in the region. In this proposal I aim to address these questions using modified DSBs repair sensors from different pathways suc",{"id":672,"funder":7,"programme":8,"title":673,"piName":10,"institution":180,"country":52,"year":13,"amount":674,"abstract":675},"cordis-european-research-council-award-851040","The genetic and neural basis of reproductive isolation","€1,499,540","Speciation is a fundamental evolutionary process, which relies on the accumulation of reproductive barriers. These barriers often act before mating, and many taxa remain separate not because they fail to produce viable offspring, but because they ‘choose’ not to mate in the first place. Although the significance of behavioural barriers has long been recognized, an integrated understanding remains elusive: How is behavioural isolation mediated through changes in the sensory systems? Are these cha",{"id":677,"funder":7,"programme":8,"title":678,"piName":10,"institution":273,"country":274,"year":13,"amount":679,"abstract":680},"cordis-european-research-council-award-852751","Solution-Based Engineering of Nanodimensional Phase-Change Materials and Memory Devices","€1,604,600","Phase-change memory (PCM) is a recently-commercialized next-generation memory storage technology that provides a sustainable solution to exponentially-growing memory storage demands of modern society. It is based on resistively switched structural changes of memory cell upon local crystallization and melting phase transitions, resulting in amorphous or crystalline atomic structures with distinctly different “0” and “1” resistance states. PCM is faster and more durable than state-of-the-art non-v",{"id":682,"funder":7,"programme":8,"title":683,"piName":10,"institution":684,"country":52,"year":13,"amount":685,"abstract":686},"cordis-european-research-council-award-853433","A multifaceted cancer immunotherapy based on an immune checkpoint-modulating chimeric oncolytic virus vector in combination with a dendritic cell vaccine","KLINIKUM DER TECHNISCHEN UNIVERSITÄT MÜNCHEN (TUM KLINIKUM)","€1,499,988","Despite many decades of intensive research, cancer remains a major worldwide health concern and imposes a heavy societal burden, both epidemiologically and financially. Cancer immunotherapy is rapidly transforming the face of medical oncology as an exciting paradigm shift in treating cancer by exploiting the immune system of the patient as the basis for the therapy. Although dramatic results have been achieved in a subset of patients, the responses in most solid tumors have been disappointing. H",{"id":688,"funder":7,"programme":8,"title":689,"piName":10,"institution":273,"country":274,"year":13,"amount":690,"abstract":691},"cordis-european-research-council-award-848794","Towards mastering the long-standing challenge of ageing infrastructures in corrosive environments","€1,497,815","TAMING CORROSION proposes a radically new approach to the long-standing challenge of mitigating corrosion of infrastructures – such as bridges, pipelines, etc. The socio-economic burden of replacing and repairing infrastructures due to corrosion is staggering. In the EU alone, estimates are in the range of 250 billion € annually, with an expected steep increase over the coming decades. This urgently calls for new, cost-effective corrosion mitigation strategies to prolong the useful life of agein",{"id":693,"funder":7,"programme":8,"title":694,"piName":10,"institution":695,"country":52,"year":13,"amount":696,"abstract":697},"cordis-european-research-council-award-850896","Improving health services to prevent heart attacks and strokes: Evidence for interventions (E4I) in large middle-income countries","UNIVERSITATSKLINIKUM HEIDELBERG","€1,492,375","Largely due to the ageing of their populations and changing lifestyles, middle-income countries (MICs) are facing a rapidly increasing burden of heart attacks and strokes. Most of these cardio- and cerebrovascular disease (CCVD) events are preventable through successful treatment of three major risk factors: diabetes, dyslipidaemia, and hypertension. Yet despite the existence of inexpensive and effective medications, only a small minority of adults with these risk factors in MICs successfully tr",{"id":699,"funder":7,"programme":8,"title":700,"piName":10,"institution":148,"country":64,"year":13,"amount":701,"abstract":702},"cordis-european-research-council-award-850706","The Silence of States in International Law","€1,499,763","International law is the law between States. It is identified by observing the behaviour of States and deriving rules from their behaviour. But, what happens when States do nothing? Can States be bound by their own silence? Can international law develop through the silence of States? Can States be responsible for doing nothing? What happens when States do not appear before international courts and tribunals? These questions are immensely significant for States, international courts and tribunals",{"id":704,"funder":7,"programme":8,"title":705,"piName":10,"institution":706,"country":342,"year":13,"amount":81,"abstract":707},"cordis-european-research-council-award-852977","Multi-dimensional analysis of the metal-poor Galaxy","STOCKHOLMS UNIVERSITET","The history of the cosmos is written in starlight. The stellar surface contains a fossil fingerprint of the chemical composition of its birth cloud, modulu evolutionary effects. It is therefore possible to extract detailed knowledge about the history of galaxies like the Milky Way by studying stars born at different locations and ages: Galactic archaeology. Deciphering the stellar spectra in terms of stellar properties like temperature and chemical composition, however, requires realistic 3-dime",{"id":709,"funder":7,"programme":8,"title":710,"piName":10,"institution":711,"country":575,"year":13,"amount":712,"abstract":713},"cordis-european-research-council-award-853014","Monolithic frequency comb spectrometers","TECHNISCHE UNIVERSITAET WIEN","€1,498,230","Sensors are the heart of every smart technology. Capturing data of theSensors are the heart of every smart technology. Capturing data of the pollution in the air, infections of individual plants on a field, or our current physiological condition opens a variety of new possibilities. Cost effective and compact instruments that detect biomarkers in human exhaled breath have the potential to identify a number of severe diseases and various types of cancer.Optical sensors have the capability to real",{"id":715,"funder":7,"programme":8,"title":716,"piName":10,"institution":717,"country":193,"year":13,"amount":718,"abstract":719},"cordis-european-research-council-award-851966","Endosomal control of local protein synthesis in axons","OSPEDALE SAN RAFFAELE SRL","€1,499,563","Neurons are morphologically complex cells that rely on highly compartmentalized signaling to coordinate cellular functions. The endocytic pathway is a crucial trafficking route by which neurons integrate, spatially process and transfer information. Endosomal trafficking in axons and dendrites ensures that required molecules and signaling complexes are present where and when they are functionally needed thus fulfilling essential roles in neuronal physiology. Our recent work has revealed the prese",{"id":721,"funder":7,"programme":8,"title":722,"piName":10,"institution":723,"country":93,"year":13,"amount":724,"abstract":725},"cordis-european-research-council-award-947921","Mapping biodiversity cradles and graves","UNIVERSIDAD DE VIGO","€1,499,923","Diversity is the most important asset of life on Earth. Estimates indicate that there are more than 8 million species providing us food, well-being and health. Since Darwin and Mendel, we started to understand how diversity is selected and inherited. However, where and why biodiversity originates and vanishes are fundamental questions yet to be answered. Today, we are witnessing the 6th mass extinction and thus, to maintain high levels of biodiversity for future generations, we need to protect n",{"id":727,"funder":7,"programme":8,"title":728,"piName":10,"institution":267,"country":52,"year":13,"amount":81,"abstract":729},"cordis-european-research-council-award-852457","Understanding how mitochondria compete with Toxoplasma for nutrients to defend the host cell","Once a pathogen has eluded immune defences to establish a replicative niche in the cytosol, it requires nutrients to grow—the same nutrients that host organelles need for their biogenesis and to perform cellular metabolic processes. The microbe must therefore compete with organelles for these nutrients.. This organelle-microbe competition for metabolites is a fundamental, but little understood aspect of the host–pathogen interaction. I recently defined one example of this competition, between mi",{"id":731,"funder":7,"programme":8,"title":732,"piName":10,"institution":733,"country":52,"year":13,"amount":734,"abstract":735},"cordis-european-research-council-award-850691","Retina Organoid Mechanobiology","UNIVERSITAET ULM","€1,497,175","The retina carries signatures of neuronal diseases which have been linked to mechanical abnormalities,including Glaucoma and Alzheimer’s disease. Yet no biophysical retina model exists due to a cross-disciplinarychallenge: While stem cell derived organoids mimic the retina in vitro, organoid research has beenlimited by large variations in cell and tissue organization. Mechanobiology, in turn, has revealed mechanicalsignals as essential players in regulating cellular behavior to guide organogenes",{"id":737,"funder":7,"programme":8,"title":738,"piName":10,"institution":739,"country":12,"year":13,"amount":740,"abstract":741},"cordis-european-research-council-award-850850","High-temperature Electrochemical Impedance Spectroscopy Transmission electron microscopy on energy materials","DANMARKS TEKNISKE UNIVERSITET","€1,497,550","The great challenge for humankind is to mitigate climate changes by replacing fossil fuels with renewables. We will have to store excess energy produced by solar and wind power for usage in dark and calm weather. Excess energy can be stored electrochemically by high-temperature electrolysis cells as they have the potential to store vast amounts of electrical energy by conversion to chemical fuels. Solid oxide electrolysis cell (SOEC) technology is well known and proven, but not price competitive",{"id":743,"funder":7,"programme":8,"title":744,"piName":10,"institution":267,"country":52,"year":13,"amount":745,"abstract":746},"cordis-european-research-council-award-850752","How the brain learns to see language","€1,729,000","Written information permeates our digital society. Yet, surprisingly little is known about how our brains allow us to learn how to read, that is, to see language. An obvious solution would be to simply follow children that undergo literacy instruction in school. Schooling, however, broadly involves learning in various domains. Therefore, it would not allow any firm conclusions to be drawn about the specific neuroplastic effects of becoming literate. To surmount this challenge, SLANG moves the re",{"id":748,"funder":7,"programme":8,"title":749,"piName":10,"institution":335,"country":281,"year":13,"amount":750,"abstract":751},"cordis-european-research-council-award-852387","How does the brain code time?","€1,499,875","Time underlies each and every activity and perception. And yet our knowledge about time perception remains limited. It is hindered by a division between psychological and behavioral findings on the one hand, and neuroscience findings on the other hand. The former rarely address biological constraints, while the latter rarely informs a unified theory for timing. Theories on time perception have centred on the modular nature of time perception. Is time sensed through the operation of central mecha",{"id":753,"funder":7,"programme":8,"title":754,"piName":10,"institution":755,"country":64,"year":13,"amount":756,"abstract":757},"cordis-european-research-council-award-853251","Oscillatory neural and autonomic correlates of social attunedness during early life: new mechanistic insights into how we learn to learn from one another","UNIVERSITY OF EAST LONDON","€1,499,274","We are a social species. Most infants, and young children, spend the majority of their early waking lives in the company of others. But, for practical reasons, almost everything that we know about how the brain subserves early attention and learning comes from studies that examined brain function in one individual at a time. This means that we understand lots about how children attend and learn from information presented while they are alone, viewing a computer screen - but little about how atte",{"id":759,"funder":7,"programme":8,"title":760,"piName":10,"institution":761,"country":93,"year":13,"amount":762,"abstract":763},"cordis-european-research-council-award-851647","Tracing the origin and early evolution of animal cell type regulation with genomics and single-cell approaches","FUNDACIO CENTRE DE REGULACIO GENOMICA","€1,498,070","Cell types are the fundamental units of animal multicellularity. Distinct cell types are established and maintained by specific gene regulatory networks (GRNs), as well as epigenomic mechanisms that mediate the asymmetric access to genetic information within each cell. This cell regulation results in complex metazoan functions and structures. However, cell types and their regulation have only been characterized in a few species. Therefore, the origin and evolution of animal cell types remain lar",{"id":765,"funder":7,"programme":8,"title":766,"piName":10,"institution":767,"country":318,"year":13,"amount":10,"abstract":768},"cordis-european-research-council-award-850754","Coaching as a social ritual: acting on people in a liberal-individualistic society (parenting, education, mental health care)","UNIVERSITE CATHOLIQUE DE LOUVAIN","The major goal of this project is to establish a greater understanding of the pervasive and elusive practice of coaching (empowering people so that they produce themselves the changes they need) as a ritual action which is specific to liberal-individualistic societies that support the idea of a hidden potential in each of us. This project will focus on the ways the coaching logic transforms three specific common social activities (parenting, teaching and mental health care) that have traditional",{"id":770,"funder":7,"programme":8,"title":771,"piName":10,"institution":772,"country":193,"year":13,"amount":81,"abstract":773},"cordis-european-research-council-award-850875","Light driven hybrid nanocrystal TMDC capacitors","POLITECNICO DI TORINO","Sunlight is an intermittent energy source coupled to the availability of the sun. Light-DYNAMO aims for an innovative solution to directly store the solar energy. The challenge is to implement solution-processable light-driven nanocrystal capacitors (NCCs), such as doped metal oxides. They show high charge-storage capacity accumulating multiple delocalized electrons after light absorption. This was to date shown in solution only with the additional drawback of reducing the hole with a sacrificia",{"id":775,"funder":7,"programme":8,"title":776,"piName":10,"institution":777,"country":52,"year":13,"amount":778,"abstract":779},"cordis-european-research-council-award-850861","From spatial relationships to temporal correlations: New vistas on predictive coding","ERNST STRUNGMANN INSTITUTE GGMBH","€1,750,000","During active wakefulness, cortical activity organizes itself into highly coherent patterns of gamma waves (30-80Hz). These waves are believed to be essential for cortical communication and synaptic plasticity. Their impairment is a hallmark of neurological and psychiatric disorders. Yet, it remains heavily debated what gamma waves encode, and what their precise role in information transmission is. I have recently proposed a new theory about gamma in visual cortex, building on the predictive cod",{"id":781,"funder":7,"programme":8,"title":782,"piName":10,"institution":783,"country":64,"year":13,"amount":784,"abstract":785},"cordis-european-research-council-award-852948","Biogenic Organic Crystals: From Crystal Formation to Genetically Engineered Optical Materials","UNIVERSITY OF BRISTOL","€1,966,000","Many spectacular optical phenomena in nature are produced by the interaction of light with organic crystals. Organisms exert exquisite control over the habit and organization of these crystals to determine the type of optical effect produced by using strategies beyond the state of the art in solid state chemistry. Despite their important role in animal behavior and their huge potential to inspire new optical materials, little is known about these materials. However, recent discoveries of previou",{"id":787,"funder":7,"programme":8,"title":788,"piName":10,"institution":789,"country":274,"year":13,"amount":232,"abstract":790},"cordis-european-research-council-award-852814","A lifelong transcatheter aortic valve prosthesis","UNIVERSITAT ZURICH","Transcatheter aortic valve implantation (TAVI) techniques have revolutionized the therapy options for valvular heart disease. Initially developed for elderly high-risk patients, TAVI is being extended to younger patients and may become a first-line treatment in the near future. However, the available bioprostheses for TAVI are prone to degeneration, and patients may thus require multiple re-interventions, significantly affecting their life quality. To date, a native-analogous TAVI prosthesis wit",{"id":792,"funder":7,"programme":8,"title":793,"piName":10,"institution":287,"country":12,"year":13,"amount":794,"abstract":795},"cordis-european-research-council-award-853442","Genetic admixture and its impact on domestication in the Bos genus: a model for genetic improvement of livestock","€1,499,275","BackgroundGenetic exchange across species boundaries is emerging as a much more common phenomenon than previously assumed. This introduces potentially adaptive genetic variation into recipient populations. Such interspecies admixture is believed to have played an important role in domestication events, particularly in members of the Bos genus, which uniquely harbours no fewer than five independently domesticated lineages. Understanding these independent, yet reticulated evolutionary events is of",{"id":797,"funder":7,"programme":8,"title":798,"piName":10,"institution":799,"country":52,"year":13,"amount":800,"abstract":801},"cordis-european-research-council-award-851693","Transcriptional and epigenetic control of tissue regenerative HB-EGF in autoimmune CNS inflammation","UNIVERSITATSKLINIKUM ERLANGEN","€1,499,706","Multiple Sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS), in which chronic inflammation and failure of regenerative mechanisms lead to progressive tissue destruction and accumulation of neurological deficits. Glial cells such as astrocytes induce regenerative processes in acute inflammation, but fail to inhibit tissue destruction for yet unknown reasons in chronic disease. In preliminary studies, we identified heparin-binding EGF-like growth factor (HB-EG",{"id":803,"funder":7,"programme":8,"title":804,"piName":10,"institution":323,"country":281,"year":13,"amount":805,"abstract":806},"cordis-european-research-council-award-851765","A new perspective on the metabolic pathway to neuronal dysfunction: Using organs on a chip to elucidate the role of the brain microvasculature","€1,487,438","Despite decades of research, the underpinnings of central nervous system (CNS) diseases and clear pathways to effective treatment remain elusive, mainly because of a scarcity of adequate models and methods with the capacity to elucidate human brain physiology. Recent studies suggest that high glucose levels are correlated with neuronal dysfunction and neurodegeneration, yet very little is known about the mechanisms of this relationship. Research in this vein has focused primarily on direct metab",{"id":808,"funder":7,"programme":8,"title":809,"piName":10,"institution":739,"country":12,"year":13,"amount":810,"abstract":811},"cordis-european-research-council-award-853522","Chip-Scale Self-Referenced Optical Frequency Comb Sources","€1,487,597","As a Nobel-honored technology, optical frequency combs, which consist of equidistant spectral lines, have revolutionized applications in time-keeping, and metrology as they offer unprecedented precision in frequency via self-referencing. However, conventional frequency comb systems have been confined to laboratories due to the cost, size, and power requirements of their components. This project aims to develop a chip-scale optical frequency comb source that can be self-referenced.Key components ",{"id":813,"funder":7,"programme":8,"title":814,"piName":10,"institution":815,"country":342,"year":13,"amount":816,"abstract":817},"cordis-european-research-council-award-852529","Modelling revolUtion for Complex flUid flow over Surfaces and walls","KUNGLIGA TEKNISKA HOEGSKOLAN","€1,499,987","Complex fluids transport and flow over surfaces governs the production of many European and global industries, along with natural hazards. Unability to predict and control such flows leads to technological barriers for novel applications (such as 3D printing, with groundbreaking potential from tissue engineering to sustainable foods). Traditional process industries waste energy when trying to improve mixing and prevent clogging (10% of the energy consumption of the world is estimated to come fro",{"id":819,"funder":7,"programme":8,"title":820,"piName":10,"institution":273,"country":274,"year":13,"amount":821,"abstract":822},"cordis-european-research-council-award-949272","Distributed Optimization Beyond Worst-Case Topologies","€1,540,000","Modern systems are increasingly dezentralized and massively distributed computations play a vital role in the systems of the future. This project aims to advance the foundational aspects of distributed computing, particularly MessagePassing algorithms for optimization problems. The strong shift towards distributed systems also lead to a flurry of works on such algorithms -- many optimization problems now have distributed algorithms with optimal worst-case performance guarantees. Generally, these",{"id":824,"funder":7,"programme":8,"title":825,"piName":10,"institution":384,"country":281,"year":13,"amount":81,"abstract":826},"cordis-european-research-council-award-853500","Plasmon Enhanced Photocatalytic Nano Lithography","The emergence of nanoscience and nanotechnology, with envisioned applications spanning from nano-optics and nano-photonics, to plasmonics and nano-electronics, depends on the capability to fabricate a variety of nanometre-scale structures. Despite the impressive development in these fields, breakthroughs remain in the laboratory, largely due to technological limitations in the ability to manufacture complex and accurate nanometer-resolved surface patterns, with satisfying resolution and on large",{"id":828,"funder":7,"programme":8,"title":829,"piName":10,"institution":180,"country":52,"year":13,"amount":830,"abstract":831},"cordis-european-research-council-award-947611","Thrombotic MEMOry-Linking a break in tolerance to platelets to REthrombosis","€1,483,145","Thrombotic diseases like venous thromboembolism (VTE) are leading causes of mortality worldwide, due to their unpredictable, relapsing occurrence. The strongest predictor of a thrombotic event is a previous thrombosis, implicating that VTE has systemic memory effects beyond local clot formation triggering thrombotic relapse. In T-MEMORE, I will go beyond the state-of-the art of thrombosis research by testing the ground-breaking concept that VTE is not only a local event, but a chronic, systemic ",{"id":833,"funder":7,"programme":8,"title":834,"piName":10,"institution":273,"country":274,"year":13,"amount":835,"abstract":836},"cordis-european-research-council-award-851544","The Heliosphere and the Dust: Characterization of the  Solar and Interstellar Neighbourhood","€1,484,038","The Sun and the surrounding heliosphere move through a low-density region in the Galaxy, which is filled with partially ionized gas and interstellar dust. While the Voyager 1 and 2 missions are currently exploring the heliosphere boundary regions that are shaped by both the Sun and by the Local Interstellar Medium (LISM), fundamental questions about our galactic neighbourhood remain unanswered: how is the structure and dynamics of the heliosphere, how does the heliosphere-LISM interaction work, ",{"id":838,"funder":7,"programme":8,"title":839,"piName":10,"institution":287,"country":12,"year":13,"amount":840,"abstract":841},"cordis-european-research-council-award-851871","Decolonising madness? Transcultural psychiatry, international order and the birth of a global psyche in the aftermath of the Second World War","€1,499,952","This project will provide crucial insights into the debate on the universality and cross-cultural applications of the notions of mental health and illness by offering the first and inter-disciplinary account of the historical origins and development of the concept of ‘global psyche’ and transcultural psychiatry. It will offer the first historical analysis of the colonial and post-colonial roots of the current global mental health movement, and the first systematic account of the decolonisation o",{"id":843,"funder":7,"programme":8,"title":844,"piName":10,"institution":148,"country":64,"year":13,"amount":845,"abstract":846},"cordis-european-research-council-award-853413","Elucidating the Basal Ganglia Circuits  for Reward Expectation","€1,498,100","Predicting future outcomes is fundamental for adaptive behaviour. Reward-predicting stimuli evoke a state of expectation, which informs motivation, guides attention, and drives preparatory motor behaviour. Reward expectations are crucial for learning since they serve as a comparison to actual outcomes. This comparison allows animals to determine if there is a prediction error (i.e. if an outcome was better or worse than expected). Even though reward expectation signals are observed in many areas",{"id":848,"funder":7,"programme":8,"title":849,"piName":10,"institution":850,"country":64,"year":13,"amount":851,"abstract":852},"cordis-european-research-council-award-851538","Bayesian Models and Algorithms for Fairness and Transparency","THE UNIVERSITY OF SUSSEX","€1,443,697","EU's GDPR prescribes that Personal Data shall be processed lawfully, fairly, and in a transparent manner. The vision of this BayesianGDPR project is to integrate into automated machine learning systems using a novel Bayesian approach, in a transparent manner, the legal non-discriminatory principles of GDPR, taking into account feedback from humans and future consequences of their outputs.    We aim to achieve this ambitious vision by 1) developing a machine learning framework for addressing fair",{"id":854,"funder":7,"programme":8,"title":855,"piName":10,"institution":856,"country":93,"year":13,"amount":232,"abstract":857},"cordis-european-research-council-award-853459","Interactive Machine Learning for Compositional Models of Natural Language","UNIVERSITAT POLITECNICA DE CATALUNYA","INTERACT will develop new Interactive Learning Algorithms (ILA), motivated by applications in Natural Language Understanding (NLU). The main assumptions behind supervised approaches are unrealistic because most NLU applications have unique information needs, and large collections of annotated data are necessary to achieve good performance. INTERACT follows a collaborative machine learning paradigm that breaks the distinction between annotation and training. We focus on compositional latent-state",{"id":859,"funder":7,"programme":8,"title":860,"piName":10,"institution":317,"country":318,"year":13,"amount":81,"abstract":861},"cordis-european-research-council-award-851622","The origin of cosmic dust in galaxies","Dust pervades the Universe; it is responsible for the obscuration of 50% of starlight, for the formation of molecular hydrogen, for the cooling of clouds collapsing to form stars, and for radiative feedback processes capable of driving massive galactic outflows. Due to the unknown origin of dust, cosmological simulations lack detailed dust physics, which will affect the outcome of galaxy evolution models.   Current work by myself and collaborators have delivered observational evidence for the ef",{"id":863,"funder":7,"programme":8,"title":864,"piName":10,"institution":280,"country":281,"year":13,"amount":865,"abstract":866},"cordis-european-research-council-award-949083","A Graph Theoretic Approach for Resilient Distributed Algorithms","€1,450,085","Following the immense recent advances in distributed networks, the explosive growth of the Internet, and our increased dependence on these infrastructures, guaranteeing the uninterrupted operation of communication networks has become major objective in network algorithms. The modern instantiations of distributed networks, such as, the Bitcoin network and cloud computing, introduce in addition, new security challenges that deserve urgent attention in both theory and practice.  The goal of this pr",{"id":868,"funder":7,"programme":8,"title":869,"piName":10,"institution":180,"country":52,"year":13,"amount":870,"abstract":871},"cordis-european-research-council-award-852205","The Arts of Autonomy: Pamphleteering, Popular Philology, and the Public Sphere, 1988-2018","€1,229,665","Concise, massively ideological texts have long been perceived as constitutive of the development and transformation of opinion and policy in the public sphere. At least since the early Enlightenment, the pamphlet has been at the forefront of major philosophical, social, and political transformations, including processes of democratization and dedemocratization, colonization and decolonization, the universalization of civil and civic rights, the enforcement of political or territorial autonomy, a",{"id":873,"funder":7,"programme":8,"title":874,"piName":10,"institution":384,"country":281,"year":13,"amount":875,"abstract":876},"cordis-european-research-council-award-851919","mesoscale multi-mode MRI of molecular targets","€1,946,250","Imaging defined cells, over extended time, depends on signal strength, stability, accessibility and specificity. Whereas light-microscopy (LM) can provide these, it does not allow imaging of entire intact tissues; imaging-depths and area-size are restricted, and not easily obtained through skin and bone. Magnetic Resonance Imaging (MRI) outperforms LM in these instances; providing images of large-fields-of-view (i.e., mesoscale), at any depth, easily across bone. Nevertheless, MRI suffers from l",{"id":878,"funder":7,"programme":8,"title":879,"piName":10,"institution":880,"country":52,"year":13,"amount":881,"abstract":882},"cordis-european-research-council-award-850760","Lebanon's Art World at Home and Abroad: Trajectories of artists and artworks in\u002Ffrom Lebanon since 1943","MAX WEBER STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND","€1,498,813","This project takes an ambitious approach to investigating the trajectories of artists and their works in and from Lebanon since its independence in 1943. In the absence of an institutionalised local art history, artists are often stereotyped according to the agendas of labelling institutions. The project proposes a shift of perspective in approaching Lebanons art world by placing emphasis on the multi-dimensionality of artists individual trajectories. It investigates (1) the forces that have sha",{"id":884,"funder":7,"programme":8,"title":885,"piName":10,"institution":148,"country":64,"year":13,"amount":886,"abstract":887},"cordis-european-research-council-award-949995","Minimum Wages, (Mis)Allocation of Labour, and Inequality","€1,102,262","Over the last two decades, wage and income inequality have increased sharply in most developed countries which is causing ever greater concern in the economic and political debate. A central challenge for policymakers is to develop measures that can simultaneously improve the distribution of economic resources and also foster economic growth. In our proposed research, we will study the effectiveness of a particular prominent instrument to achieve this goal - the minimum wage. First, we will prov",{"id":889,"funder":7,"programme":8,"title":890,"piName":10,"institution":891,"country":64,"year":13,"amount":892,"abstract":893},"cordis-european-research-council-award-851758","Temporal Laser cavity-Solitons for micro-resonator based optical frequency combs","LOUGHBOROUGH UNIVERSITY","€1,494,683","Precise timing has led to many advances, such as GPS and the Internet, which depend critically on frequency and time standards. The currently limited accuracy, however, is hindering the progress towards societal-changing technologies such as telecommunications beyond 5G or precise earth mapping.Optical atomic clocks based on optical frequency combs – Nobel prize in Physics, 2005 to Hall and Hänsch – are the only technology capable of providing timing accurate up to 10^(-18) seconds, answering su",{"id":895,"funder":7,"programme":8,"title":896,"piName":10,"institution":897,"country":193,"year":13,"amount":898,"abstract":899},"cordis-european-research-council-award-848411","Attosecond Dynamics in Advanced Materials","POLITECNICO DI MILANO","€1,466,250","Speed and performances of contemporary digital electronics are limited by the available device architectures and heat dissipation. Two-dimensional (2D) materials are emerging as one of the main candidates for designing new structures capable to overcome the current device limitations and foster the establishment of the electronics of the future. Due to the electron confinement in two directions, they are characterised by exotic physical, electronic and chemical properties, which are neither full",{"id":901,"funder":7,"programme":8,"title":902,"piName":10,"institution":373,"country":64,"year":13,"amount":903,"abstract":904},"cordis-european-research-council-award-852674","Fundamental and Applied Science using Two Dimensional Angstrom-scale capillaries","€1,619,466","I will construct and apply next generation capillary devices as an exciting experimental platform to enable ground-breaking investigation of structure and dynamics of water at the ultimate molecular scale. These devices are in a lab-on-a-chip type configuration with angstrom-scale channels and atomically smooth walls. I am making them by scrupulous assembly tools in a controllable and reproducible fashion and they are extremely stable. Myself and my team will assemble capillaries of a few micron",{"id":906,"funder":7,"programme":8,"title":907,"piName":10,"institution":908,"country":281,"year":13,"amount":10,"abstract":909},"cordis-european-research-council-award-852952","Homomorphic Secret Sharing: Secure Computation and Beyond","REICHMAN UNIVERSITY","Secure computation is a powerful cryptographic tool that enables distrusting parties to jointly emulate the correctness and privacy guarantees of an incorruptible trusted third party.The past decades have seen tremendous progress in secure computation protocol design, yet there remain significant gaps in our understanding. On one hand, classical approaches require excessive communication between parties",{"id":911,"funder":7,"programme":8,"title":912,"piName":10,"institution":850,"country":64,"year":13,"amount":913,"abstract":914},"cordis-european-research-council-award-852730","Governing sustainable energy-mobility transitions:  multi-level policy mixes, transformative capacities and low-carbon innovations","€1,499,964","In its recent 1.5°C report the IPCC stressed that global efforts to promote low-carbon transitions need to be accelerated to meet the Paris Agreement. This raises a number of questions for the emerging field of policy mixes for sustainability transitions, such as on the role of actors and multi-level governance in politically contested socio-technical transition processes. In this project, I aim to address these knowledge gaps by asking how low-carbon transitions in the increasingly interconnect",{"id":916,"funder":7,"programme":8,"title":917,"piName":10,"institution":918,"country":193,"year":13,"amount":919,"abstract":920},"cordis-european-research-council-award-947715","Positron resonant annihilation into darK mattER","ISTITUTO NAZIONALE DI FISICA NUCLEARE","€1,484,853","The goal of POKER is to establish and demonstrate a new approach to search for light dark matter, based on a missing energy measurement with a positron-beam, active thick-target setup. Light dark matter is the new compelling hypothesis that identifies dark matter with new sub-GeV Hidden Sector states, neutral under Standard Model interactions and interfacing with our world through a new force. Accelerator-based searches at the intensity frontier are uniquely suited to explore it. However, curren",{"id":922,"funder":7,"programme":8,"title":923,"piName":10,"institution":924,"country":52,"year":13,"amount":925,"abstract":926},"cordis-european-research-council-award-851393","The Prison Narratives of Assad's Syria: Voices, Texts, Publics","FORUM TRANSREGIONALE STUDIEN EV","€1,175,239","SYRASP combines textual analysis of Syrian prison literature with interviews on narrative and memory among former political prisoners. Between the late 1970s and early 2000s, the Assad regime imprisoned thousands of opponents from the secular left and Muslim Brotherhood, as well as their family members and associates. Political prisoners were held indefinitely in large group cells, often exclusively with members of their parties. By addressing their prison narratives as a diverse set of oral and",{"id":928,"funder":7,"programme":8,"title":929,"piName":10,"institution":323,"country":281,"year":13,"amount":930,"abstract":931},"cordis-european-research-council-award-949850","Redefining the term 'Incubation Period' using large-scale digital data","€1,986,875","Infectious diseases pose one of the greatest risks for a global catastrophe. Just like controlling the spread of wildfires, an early detection of infectious diseases is instrumental to containing outbreaks. Nearly all infections start silently, and gradually progress until clinical symptoms appear. In this silent period, the incubation period (IP), pathogens inhibit major pathways of the innate immune system, allowing an extended period of unhindered replication. The rate of replication, as well",{"id":933,"funder":7,"programme":8,"title":934,"piName":10,"institution":935,"country":64,"year":13,"amount":936,"abstract":937},"cordis-european-research-council-award-805425","Slavery, Work and Freedom: What Can Cash Transfers Contribute to the Fight for Decent Work?","UNIVERSITY OF BATH","€1,499,203","WorkFREE builds on the widespread empirical observation that everywhere people who are stuck in indecent, exploitative or ‘unfree’ work nevertheless choose that work because doing so represents their best available option, and asks a simple yet potentially revolutionary question: What happens if we just give them money? It will answer this question by creating a world-first social experiment. This will involve a community in the Indian city of Hyderabad typically associated with indecent or expl",{"id":939,"funder":7,"programme":8,"title":940,"piName":10,"institution":941,"country":274,"year":13,"amount":942,"abstract":943},"cordis-european-research-council-award-847456","Dynamical constraints for the predictability of heat waves in current and future climates","UNIVERSITE DE LAUSANNE","€1,499,849","In summer 2018, a devastating heat wave affected the entire Northern Hemisphere. Climate change projections indicate that the severity and frequency of such heat waves will further increase over the next decades. At the same time, models remain unable to predict heat waves at lead times of a few weeks  a crucial planning timescale. The poor prediction skill at timescales of weeks to months is to a large extent due to an incomplete understanding of the underlying physical drivers of heat waves. I",{"id":945,"funder":7,"programme":8,"title":946,"piName":10,"institution":947,"country":575,"year":13,"amount":948,"abstract":949},"cordis-european-research-council-award-851470","Toxin-antidote selfish elements in animals: from gene drive to speciation","INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH","€1,498,428","Toxin-antidote (TA) elements are a class of selfish elements that spread in natural populations by subverting the laws of Mendelian segregation (gene drive activity).  For a decade, the only known TA element in animals was a paternal-acting element discovered in the nematode C. elegans. The lack of other examples perpetuated the idea that TA elements were extremely rare in animals. However, I recently challenged this view with two key findings 1) I genetically dissected a second TA element in C.",{"id":951,"funder":7,"programme":8,"title":952,"piName":10,"institution":10,"country":10,"year":13,"amount":953,"abstract":954},"cordis-european-research-council-award-852821","Signals, Waves, and Learning: A Data-Driven Paradigm for Wave-Based Inverse Problems","€1,986,430","Scattering of waves governs fundamental questions in science, from imaging molecules to fine-tuning concert hall acoustics. Efficient scattering computations rely on sparse representations of wavefields. Spurred by the empirical successes of deep learning, the emphasis has recently shifted to data-driven modeling. However, unlike signal-theoretic implementations that come with sharp approximation guarantees, it remains unclear whether the popular deep learning structures can represent important ",{"id":956,"funder":7,"programme":8,"title":957,"piName":10,"institution":958,"country":52,"year":13,"amount":959,"abstract":960},"cordis-european-research-council-award-852178","From iPSC-Macrophage Biology Towards Regenerative Therapies Targeting Respiratory Infections","MEDIZINISCHE HOCHSCHULE HANNOVER","€1,499,100","Tissue resident macrophages (TRMs) can be found in various organs and fulfil important functions in host defence and tissue homeostasis. Recent studies in the murine system suggest profound tissue plasticity and self-renewal capacity of TRMs, rendering this cell population highly suitable for new cell-based therapies. Mycobacterial infections represent a serious health problem, for which new therapies are highly needed. Given the important role of alveolar macrophages (MΦs) in pulmonary host def",{"id":962,"funder":7,"programme":8,"title":963,"piName":10,"institution":317,"country":318,"year":13,"amount":964,"abstract":965},"cordis-european-research-council-award-853517","Outside-in: How Bullying in Adolescence Gets Into The Mind and Under the Skin","€1,494,044","Being bullied is a major stressor for many adolescents and it is recognized as a public health concern worldwide. Adolescents who are exposed to bullying are at increased risk for mental and physical health problems, which could even perpetuate into adulthood. Unfortunately, current understandings of how bullying can pose such deleterious effects remain poor, thus limiting our ability to inform prevention and intervention efforts. This project addresses this fundamental gap and substantially ext",{"id":967,"funder":7,"programme":8,"title":968,"piName":10,"institution":969,"country":52,"year":13,"amount":750,"abstract":970},"cordis-european-research-council-award-852761","Dissection of Bioenergetic Plasticity of Tumors","TECHNISCHE UNIVERSITAET DRESDEN","Tumors reprogram their metabolism to fuel rapid growth. Glycolysis and oxidative phosphorylation “OXPHOS” are the main energy-producing pathways. For decades, metabolic reprogramming of tumors was perceived as only increased glycolysis (Warburg effect). This dogma has recently been revised as we started to realize the importance of OXPHOS in tumor metabolism. We are now entering a new era as metabolomics studies show that tumor metabolism is more heterogeneous than initially assumed. In the prep",{"id":972,"funder":7,"programme":8,"title":973,"piName":10,"institution":974,"country":52,"year":13,"amount":975,"abstract":976},"cordis-european-research-council-award-851374","Turbulence-Resolving Approaches to the Intermittently Turbulent Atmospheric Boundary Layer","FREIE UNIVERSITAET BERLIN","€1,872,581","Vertical exchange in the atmospheric boundary is primarily due to turbulence, but turbulence may cease locally as a consequence of stable density stratification. This state of turbulence intermittency challenges traditional geophysical approaches to represent turbulent mixing. Field observations of the phenomenon are hard to obtain because of broad-scale interacting processes. Existing numerical approaches based on bulk turbulence closures reach their limits because they neglect the relevance of",{"id":978,"funder":7,"programme":8,"title":979,"piName":10,"institution":980,"country":342,"year":13,"amount":981,"abstract":982},"cordis-european-research-council-award-949424","Neolithic Seafaring and Maritime Technologies shaped a New World of Megalithic Societies (4700-3500 cal BC)","GOETEBORGS UNIVERSITET","€1,499,973","The NEOSEA project will investigate Neolithic seafaring and maritime technologies, and their role in shaping a new interconnected world of megalithic societies. Recent research into megalithic temporality, mobility and symbolic identity suggests that the rise of long-distance maritime journeys began in Europe as early as the megalithic era. Megaliths emerged in Northwest France (~4700-4200 cal BC) and then spread over the seaways along Europes Atlantic and Mediterranean coasts. This new discover",{"id":984,"funder":7,"programme":8,"title":985,"piName":10,"institution":986,"country":274,"year":13,"amount":987,"abstract":988},"cordis-european-research-council-award-851720","An Artificial Assistant for Software Developers","UNIVERSITA DELLA SVIZZERA ITALIANA","€1,499,093","Software development, also due to the complexity of software systems, is tackled by collaborating teams of people. For example, in pair programming two developers share a single workstation: One writes code, while the other reviews it and proposes ideas for improvement. While interacting with teammates is the preferred means to obtain help, their availability may fall short and they might not always have a solution at hand. To address this problem, recommender systems for developers have been pr",{"id":990,"funder":7,"programme":8,"title":991,"piName":10,"institution":992,"country":575,"year":13,"amount":993,"abstract":994},"cordis-european-research-council-award-851478","Therapeutic hijacking of E3 Ligases","CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH","€1,331,340","Traditional drug design relies on inhibition of enzymes or receptors with accessible hydrophobic pockets. The concept of proteolysis targeting chimeras (PROTACs) promised to overcome this limitation. Following our discovery of the first PROTAC that induced selective protein degradation in vivo, this technology has seen a boost in academia and industry. Despite global research efforts, advances are so far incremental: (i) most focus is on degrading targets that can be liganded and are druggable w",{"id":996,"funder":7,"programme":8,"title":997,"piName":10,"institution":998,"country":999,"year":13,"amount":1000,"abstract":1001},"cordis-european-research-council-award-853566","FAKE NEWS AND REAL PEOPLE – USING BIG DATA TO UNDERSTAND HUMAN BEHAVIOUR","LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS LIP","PT","€1,499,844","Recent events, from the anti-vaccination movement, to Brexit and even to mob killings, have raised serious concerns about the influence of the so-called fake news (FN). False information is not new in human history, but the recent surge in online activity, coupled with poor digital literacy, consumer profiling, and large profits from ad revenues, created a perfect storm for the FN epidemic, with still unimaginable consequences. This challenge is interdisciplinary and requires academic research t",{"id":1003,"funder":7,"programme":8,"title":1004,"piName":10,"institution":1005,"country":100,"year":13,"amount":1006,"abstract":1007},"cordis-european-research-council-award-848532","Papuans on the move. The linguistic prehistory of the West Papuan languages.","STICHTING VU","€1,499,684","This project combines urgent documentation of endangered languages in Indonesia with rigorous investiga-tion of a linguistic puzzle that has important implications for our understanding of both Melanesian and Southeast Asian prehistory. Some two dozen Papuan languages, scattered over a 1000km on and around the Bird's Head of West Papua, show signs of sharing a common origin. The OUTOFPAPUA project uses cut-ting-edge methods in historical linguistics to test the hypothesis that these languages be",{"id":1009,"funder":7,"programme":8,"title":1010,"piName":10,"institution":1011,"country":274,"year":13,"amount":1012,"abstract":1013},"cordis-european-research-council-award-853546","Human Placental Development  and the Uterine Microenvironment","FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION","€1,992,098","How does the human placenta develop and how is this influenced by the maternal uterine microenvironment? These are the central questions addressed in my proposal. Normal growth and development of the fetus depends on the placenta, the extra-embryonic organ derived from trophectoderm. Successful pregnancy depends on the earliest stages of development when placental extravillous trophoblast cells (EVT) infiltrate the uterine mucosa, the decidua. EVT invade the decidua to transform the uterine spir",{"id":1015,"funder":7,"programme":8,"title":1016,"piName":10,"institution":323,"country":281,"year":13,"amount":1017,"abstract":1018},"cordis-european-research-council-award-852953","Informational properties of networks under communication constraints","€1,474,375","Motivated by applications to information networks such as wireless and ad-hoc, this research will explorefundamental informational properties of networks under communication constraints. In the standardapproach, the network is assumed to be fully connected and\u002For the information it carries is treated as acommodity. Here, we will investigate a markedly different paradigm where limitations on the nodes’connectivity in the network are imposed and pieces of information can be combined. Examples incl",{"id":1020,"funder":7,"programme":8,"title":1021,"piName":10,"institution":1022,"country":52,"year":13,"amount":1023,"abstract":1024},"cordis-european-research-council-award-850533","Learning Generative 3D Scene Models for Training and Validating Intelligent Systems","EBERHARD KARLS UNIVERSITAET TUEBINGEN","€1,467,500","Recently, the field of computer vision has witnessed a major transformation away from expert designed shallow models towards more generic deep representation learning. However, collecting labeled data for training deep models is costly and existing simulators with artist-designed scenes do not provide the required variety and fidelity. Project LEGO-3D will tackle this problem by developing probabilistic models capable of synthesizing 3D scenes jointly with photo-realistic 2D projections from arb",{"id":1026,"funder":7,"programme":8,"title":1027,"piName":10,"institution":384,"country":281,"year":13,"amount":1028,"abstract":1029},"cordis-european-research-council-award-853096","Thermophone - a novel heat transfer based approach to global TOnal Noise cancellation in aviation","€1,993,265","Limiting the number of people affected by significant aircraft noise is one of the most important tasks of modern civil aviation. Among different contributors, tonal noise is the most important due to regulatory definitions and its attenuation characteristics, with the largest contributor being the fan aero-acoustics. Current passive noise reduction methods alone are insufficient to conform with the increasingly stringent noise emission regulations. This motivates our research in active noise ca",{"id":1031,"funder":7,"programme":8,"title":1032,"piName":10,"institution":1033,"country":52,"year":13,"amount":10,"abstract":1034},"cordis-european-research-council-award-851181","The role of non-growing season processes in the methane and nitrous oxide budgets in pristine northern ecosystems","ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG","The response of the terrestrial biosphere to climate change is still largely unknown and represents a key uncertainty in climate change predictions. High latitude regions, including Arctic and boreal ecosystems, constitute a key component of the earth system due to significant soil carbon stocks. High latitude regions are net sources of greenhouse gases, such as methane (CH4) and nitrous oxide (N2O), but there is significant disagreement among flux estimates with further uncertainty due to a rap",{"id":1036,"funder":7,"programme":8,"title":1037,"piName":10,"institution":1038,"country":93,"year":13,"amount":1039,"abstract":1040},"cordis-european-research-council-award-850604","The Secret Life of Writing: People, Script and Ideas in the Iberian Peninsula (c. 900-1200)","UNIVERSIDAD DE SALAMANCA","€995,040","As a rule, only those medieval manuscripts that were of interest for the powerful have been preserved. Extant codices were cherished throughout centuries as tangible signs of cultural pre-eminence and carriers of the sacred word; charters were kept as custodians of patrimony and witness to the history of institutions, proclaiming the reasons why monasteries and cathedrals should be revered. But against this rule, other manuscripts that did not directly serve the purposes of high-status minoritie",{"id":1042,"funder":7,"programme":8,"title":1043,"piName":10,"institution":1044,"country":318,"year":13,"amount":1045,"abstract":1046},"cordis-european-research-council-award-851752","Celluloepidemiology: a novel paradigm for modeling T-cell responses on a population level.","UNIVERSITEIT ANTWERPEN","€1,499,734","As a paediatrician who specialized in immunology and as a physicist who specialized in mathematical modeling of infectious diseases, I want to introduce with this project a paradigm shift in infectious disease epidemiology through the concept of celluloepidemiology.Celluloepidemiology is a term I invented to describe my proposed interdisciplinary approach combining unique cellular immune responses against pathogens on a population level with mathematical modeling, thereby generating unique and o",{"id":1048,"funder":7,"programme":8,"title":1049,"piName":10,"institution":1050,"country":93,"year":13,"amount":1051,"abstract":1052},"cordis-european-research-council-award-852741","Global existence and Computer-Assisted Proofs of singularities in incompressible fluids, with Applications","UNIVERSITAT DE BARCELONA","€1,483,073","The goal of this proposal is twofold: on the one hand to pursue methods and ideas developed in recent work in the search for either singularities or global existence in incompressible fluids with finite energy and on theother transfer the techniques to solve long-standing open problems in spectral geometry. A key ingredient in its success is to have accurate numerics together with a deep understanding of the regularity theory. Therefore, the interdisciplinary nature of this project, which involv",{"id":1054,"funder":7,"programme":8,"title":1055,"piName":10,"institution":1056,"country":52,"year":13,"amount":81,"abstract":1057},"cordis-european-research-council-award-851810","Quantum Repeater Architectures Based on Quantum Memories and Photonic Encoding","HUMBOLDT-UNIVERSITAET ZU BERLIN","At the heart of all anticipated network-based quantum applications lies the requirement to establish quantum communication between individual network nodes over long distances. Quantum communication exceeding 100 km requires so-called quantum repeaters to extend communication beyond this limit. Mainly two types of quantum repeater schemes are being investigated: Quantum-memory-based schemes for long-distant entanglement generation and photonic encoding-based schemes for fast secure quantum commu",{"id":1059,"funder":7,"programme":8,"title":1060,"piName":10,"institution":1061,"country":193,"year":13,"amount":1062,"abstract":1063},"cordis-european-research-council-award-853057","Promyelocytic leukemia protein (PML) outside the tumor: a new player in the control of inflammation","UNIVERSITA DEGLI STUDI DI FERRARA","€1,462,500","Local sterile inflammation arise in many pathologic states, including several diseases of the nervous system as brain stroke, neurodegenerative diseases and epilepsy. The persistent and de-regulated inflammatory response sustains these neurological pathologies worsening their prognosis. Different molecular players, as NLRP3 and P2X7 have been shown to contribute to the progression of these illnesses triggering the release of IL-1β and recruiting cellular components of the immune response at the ",{"id":1065,"funder":7,"programme":8,"title":1066,"piName":10,"institution":535,"country":100,"year":13,"amount":232,"abstract":1067},"cordis-european-research-council-award-852732","DYNAMICS OF THE DURABLE. A History of Making Things Last in the Visual and Decorative Arts.","Our cultural heritage comprises many art objects that are hundreds, some thousands of years old. How did they survive this long? While many factors determine if and how art can be preserved, one has fundamentally impacted its long-term survival: the desire to make and own artefacts that withstand the test of time. This project—DURARE—will undertake the first comprehensive study of the impact of the artisan and patron’s ambitions to craft, own and theorize durable objects on the long-term develop",{"id":1069,"funder":7,"programme":8,"title":1070,"piName":10,"institution":1071,"country":52,"year":13,"amount":1072,"abstract":1073},"cordis-european-research-council-award-852065","3D-printing of PARTiculate FORMulations utilizing polymer microparticle-based voxels","OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG","€1,474,125","New polymer materials are necessary to match the demand for highly integrated, multifunctional, responsive systems for sensing, information processing, soft robotics or multi-parametric implants. Both establishedmaterial design concepts based on lithography, and emerging engineering efforts based on additive manufacturing (AM) are currently not able to fully address the need for topologically complex, multifunctionaland stimuli-responsive polymer materials. This proposal aims at establishing a r",{"id":1075,"funder":7,"programme":8,"title":1076,"piName":10,"institution":1077,"country":52,"year":13,"amount":1078,"abstract":1079},"cordis-european-research-council-award-948424","The Role of Memory for Economic Belief Formation","FORSCHUNGSINSTITUT ZUR ZUKUNFT DERARBEIT GMBH","€1,279,361","Beliefs and expectations play a major role in economic analysis. In the proposed research, I seek to advance our empirical understanding of belief and expectation formation processes by incorporating memory patterns. Intuitively, memory plays a crucial role in the process of belief formation and the evolution of belief distortions, as large parts of the information used when forming beliefs is retrieved from memory. While recent theoretical work has begun to recognize the important role of memor",{"id":1081,"funder":7,"programme":8,"title":1082,"piName":10,"institution":1083,"country":52,"year":13,"amount":10,"abstract":1084},"cordis-european-research-council-award-851423","Sociolinguistic typology and responsive features in syntactic history","UNIVERSITAT KONSTANZ","The aim of this project is to develop and test a new theory of variation and change in syntactic complexity, building on Trudgill’s (2011) theory of sociolinguistic typology and on the general architectural assumptions of Minimalist syntax. Trudgill (2011) makes the case that the distribution of simplicity and complexity across the world’s languages is related to the historical circumstances involved, with intense short-term contact involving extensive adult second language acquisition leading t",{"id":1086,"funder":7,"programme":8,"title":1087,"piName":10,"institution":1088,"country":20,"year":13,"amount":1089,"abstract":1090},"cordis-european-research-council-award-853049","Creating the new generation of 2D light emitters","ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS","€1,493,479","Semiconductor nanocrystals (NCs) have size tuneable optical features. Among them, nanoplatelets (NPLs) are 2D NCs with especially well controlled optical features. As a result, these are the semiconductor nanoparticles with the narrowest luminescence signal, which make them very appealing for light emission application and in particular large gamut displays. In the Ne2DeM project, the NPLs will be used as a platform for the design of a new generation of light emitters which applications span fro",{"id":1092,"funder":7,"programme":8,"title":1093,"piName":10,"institution":1022,"country":52,"year":13,"amount":1094,"abstract":1095},"cordis-european-research-council-award-849189","Refugees and Revolution in the Atlantic World, 1770s-1820s","€1,495,778","This project explores movements and networks of refugees and exiles of the revolutions in the Americas and Europe (1770s–1820s). Political modernity, brought about by the “age of revolutions” and often identified with new notions of sovereignty and citizenship, was intertwined with the emergence of the political refugee as a mass phenomenon. Unprecedented numbers of people—in total, well over a quarter million—sought refuge in countries other than their own on primarily political, rather than re",{"id":1097,"funder":7,"programme":8,"title":1098,"piName":10,"institution":783,"country":64,"year":13,"amount":1099,"abstract":1100},"cordis-european-research-council-award-852677","Epistemic Utility for Imprecise Probability","€1,490,433","Scientific inference is principally a matter of using observable data to estimate the parameters of models of interest, e.g., models of the climate system. In traditional Bayesian statistics, uncertainty about model parameters is quantified using a single, precise probability distribution. This approach has proved extremely successful in applications where data is plentiful and model parameters are few. But many models are high dimensional (thousands of parameters), and relevant data is comparat",{"id":1102,"funder":7,"programme":8,"title":1103,"piName":10,"institution":856,"country":93,"year":13,"amount":1104,"abstract":1105},"cordis-european-research-council-award-947657","Lifelong UNiversal lAnguage Representation","€1,498,723","Why is machine translation between English and Portuguese significantly better than machine translation between Dutch and Spanish? Why do speech recognizers work better in German than Finnish? The main problem is the insufficient amount of labelled data for training in both cases. Although the world is multimodal and highly multilingual, speech and language technology is not keeping up with the demand in all languages. 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