[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-erc-starting-grant-2022":3,"awarded-stats-erc-starting-grant":1121},{"awarded":4,"total":1120},[5,16,23,30,37,43,49,56,62,69,76,83,90,96,103,108,113,120,126,132,137,142,144,151,157,164,170,176,183,188,194,200,206,212,217,224,230,235,242,247,253,259,265,271,277,283,289,295,301,307,313,319,326,332,337,342,347,353,358,364,370,376,382,388,394,401,407,412,418,423,429,434,440,445,450,455,461,467,472,478,483,489,495,501,506,510,515,522,526,532,538,543,549,554,559,564,570,576,581,586,591,596,602,608,614,619,624,630,636,641,646,650,656,662,668,673,679,684,689,694,700,706,712,717,722,727,731,736,742,747,752,757,762,767,773,777,782,786,791,796,801,808,814,820,825,831,837,843,849,855,861,866,871,878,884,888,894,899,904,910,915,920,925,930,934,939,943,947,951,955,961,966,971,976,982,988,992,997,1003,1008,1014,1020,1024,1029,1035,1040,1044,1051,1057,1062,1068,1074,1078,1084,1090,1096,1101,1105,1110,1115],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-european-research-council-award-erc-stg-678071","European Research Council","ERC Starting Grant","Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors","Volker Busskamp","University of Bonn","DE",2022,null,"Neurodegenerative retinal diseases are a prime cause of blindness in industrialized countries. In many cases, there are no therapeutic treatments, although they are essential to improve patients' quality of life. A set of disease-causing genes, which primarily affect photoreceptors, has already been identified and is of major interest for developing gene therapies. Nevertheless, depending on the nature and the state of the disease, gene-independent strategies are needed. Various strategies to ha",{"id":17,"funder":7,"programme":8,"title":18,"piName":19,"institution":20,"country":21,"year":13,"amount":14,"abstract":22},"openalex-european-research-council-award-erc-2009-stg-243149","Mortality Risk Among Frail Neonates and Maternal BCG Vaccine Scar Status: Observational Study From Guinea-Bissau","Frederik Schaltz‐Buchholzer","Bandim Health Project","GW","BACKGROUND: Maternal priming with the Bacille Calmette-Guérin (BCG) vaccine has been associated with reduced offspring mortality rates. We investigated this association in a cohort of frail neonates. METHODS: We performed an observational study within a randomized BCG trial conducted at the neonatal intensive care unit (NICU) in Guinea-Bissau from 2015 to 2017. At NICU admission and after informed consent, the maternal scar status was evaluated by visual inspection before neonates were randomize",{"id":24,"funder":7,"programme":8,"title":25,"piName":26,"institution":27,"country":28,"year":13,"amount":14,"abstract":29},"openalex-european-research-council-award-erc-2012-stg-310005","Fabrication of a fractal pattern device for focus characterizations ofX-ray imaging systems by Si deep reactive ion etching and bottom-up Auelectroplating","Zhitian Shi","Paul Scherrer Institute","CH","Precisely aligned optical components are crucial prerequisites for X-ray tomography at high resolution. We propose a device with a fractal pattern for precise automatic focusing. The device is etched in a Si substrate by deep reactive ion etching and then filled by a self-terminating bottom-up Au electroplating process. The fractal nature of the device produces an X-ray transmission image with globally homogeneous macroscopic visibility and high local contrast for pixel sizes in the range of 0.1",{"id":31,"funder":7,"programme":8,"title":32,"piName":33,"institution":34,"country":35,"year":13,"amount":14,"abstract":36},"openalex-european-research-council-award-erc-2017-stg-sentiflex-project-grant-agreement-755617-","Improving the remote estimation of soil organic carbon in complex ecosystems with Sentinel-2 and GIS using Gaussian processes regression","Johanna Elizabeth Ayala Izurieta","Parc Científic de la Universitat de València","ES","Background and aims: The quantitative retrieval of soil organic carbon (SOC) storage, particularly for soils with a large potential for carbon sequestration, is of global interest due to its link with the carbon cycle and the mitigation of climate change. However, complex ecosystems with good soil qualities for SOC storage are poorly studied. Methods: The interrelation between SOC and various vegetation remote sensing drivers is understood to demonstrate the link between the carbon stored in the",{"id":38,"funder":7,"programme":8,"title":39,"piName":40,"institution":41,"country":12,"year":13,"amount":14,"abstract":42},"openalex-european-research-council-award-starting-grant-resolutionet-erc-stg-679158-","Measuring Web Cookies in Governmental Websites","Matthias Gotze","Technische Universität Berlin","In recent years, governments worldwide have moved their services online to better serve their citizens. Benefits aside, this choice increases the danger of tracking via such sites. This is of great concern as governmental websites increasingly become the only interaction point with the government. In this paper, we investigate popular governmental websites across different countries and assess to what extent the visits to these sites are tracked by third-parties. Our results show that, unfortuna",{"id":44,"funder":7,"programme":8,"title":45,"piName":46,"institution":47,"country":28,"year":13,"amount":14,"abstract":48},"openalex-european-research-council-award-erc-2012-stg-307442","Femtosecond laser-shockwave induced densification in fused silica","Arunkrishnan Radhakrishnan","École Polytechnique Fédérale de Lausanne","A tightly focused femtosecond laser-beam in the non-ablative regime can induce a shockwave sufficiently intense to reach local pressures in the giga-Pascal range or more. In a single beam configuration, the location of the highest-pressure zone is nested within the laser-focus zone, making it difficult to differentiate the effect of the shockwave pressure from photo-induced and plasma relaxation effects. To circumvent this difficulty, we consider two spatially separated focused beams individuall",{"id":50,"funder":7,"programme":8,"title":51,"piName":52,"institution":53,"country":54,"year":13,"amount":14,"abstract":55},"openalex-european-research-council-award-erc-2018-stg-804135","Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon","Anders Meyer Torp","Technical University of Denmark","DK","Delivery of antibiotics in microcontainer devices designed for release at specific sites of the gut represents a novel approach which might reduce the amount of antibiotic needed to obtain a local selective effect. We propose that the application of microcontainers may have the potential to open novel opportunities for antibiotic treatment of humans and animals with fewer side effects on nontarget bacterial populations. In the current study, we therefore elucidated the effects of streptomycin, d",{"id":57,"funder":7,"programme":8,"title":58,"piName":59,"institution":60,"country":61,"year":13,"amount":14,"abstract":14},"openalex-european-research-council-award-erc-2017-stg-759782","Walking strides direct rapid and flexible recruitment of visual circuits for course control in Drosophila","M Eugenia Chiappe","Champalimaud Foundation","PT",{"id":63,"funder":7,"programme":8,"title":64,"piName":65,"institution":66,"country":67,"year":13,"amount":14,"abstract":68},"openalex-european-research-council-award-erc-stg-638589","Intra- and inter-regional dynamics in cortical-striatal-tegmental networks","Adam J. O. Dede","University of Phayao","TH","We applied novel clustering techniques to discover functional subregional anatomical patches that changed with behavioral conditions but were frequency specific and stable across days. By taking into account these changes in intraregional signal generator location and extent, we were able to reveal a richer picture of inter-regional functional connectivity than would otherwise have been possible. These findings reveal that the brain's functional organization changes with state at multiple levels",{"id":70,"funder":7,"programme":8,"title":71,"piName":72,"institution":73,"country":74,"year":13,"amount":14,"abstract":75},"openalex-european-research-council-award-erc-2017-stg","The Permeability of Porous Volcanic Rock Through the Brittle‐Ductile Transition","Michael J. Heap","Centre National de la Recherche Scientifique","FR","The permeability of volcanic rock controls the distribution of pore fluids and pore fluid pressure within a volcanic edifice, and is therefore considered to influence eruptive style and volcano deformation. We measured the porosity and permeability of a porous volcanic rock during deformation in the brittle and ductile regimes. In the brittle regime, permeability decreases by a factor of 2-6 up to the peak stress due the closure of narrow pore throats but, following shear fracture formation, rem",{"id":77,"funder":7,"programme":8,"title":78,"piName":79,"institution":80,"country":81,"year":13,"amount":14,"abstract":82},"openalex-european-research-council-award-erc-2015-stg-677289","How Reproducible are Surface Areas Calculated from the BET Equation?","Tomoya Iiyuka","The University of Tokyo","JP","Porosity and surface area analysis play a prominent role in modern materials science. At the heart of this sits the Brunauer-Emmett-Teller (BET) theory, which has been a remarkably successful contribution to the field of materials science. The BET method was developed in the 1930s for open surfaces but is now the most widely used metric for the estimation of surface areas of micro- and mesoporous materials. Despite its widespread use, the calculation of BET surface areas causes a spread in repor",{"id":84,"funder":7,"programme":8,"title":85,"piName":86,"institution":87,"country":88,"year":13,"amount":14,"abstract":89},"openalex-european-research-council-award-erc-stg-716011","Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR\u002FCas9 Gene Editing","Wouter J. Droogers","Utrecht University","NL","CRISPR\u002FCas9-mediated knock-in methods enable the labeling of individual endogenous proteins to faithfully determine their spatiotemporal distribution in cells. However, reliable multiplexing of knock-in events in neurons remains challenging because of cross talk between editing events. To overcome this, we developed conditional activation of knock-in expression (CAKE), allowing efficient, flexible, and accurate multiplex genome editing. To diminish cross talk, CAKE is based on sequential, recomb",{"id":91,"funder":7,"programme":8,"title":92,"piName":93,"institution":94,"country":35,"year":13,"amount":14,"abstract":95},"openalex-european-research-council-award-erc-2018-stg-804236-nextgen-io","Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods","Nicola G. A. Abrescia","Ikerbasque","Two years after its emergence, the coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains difficult to control despite the availability of several vaccines. The extensively glycosylated SARS-CoV-2 spike (S) protein, which mediates host cell entry by binding to the angiotensin converting enzyme 2 (ACE2) through its receptor binding domain (RBD), is the major target of neutralizing antibodies. Like to many other viral fusion prot",{"id":97,"funder":7,"programme":8,"title":98,"piName":99,"institution":100,"country":101,"year":13,"amount":14,"abstract":102},"openalex-european-research-council-award-stg-801659","The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor","Ritvija Agrawal","University of Michigan","US","Dynein harnesses ATP hydrolysis to move cargo on microtubules in multiple biological contexts. Dynein meets a unique challenge in meiosis by moving chromosomes tethered to the nuclear envelope to facilitate homolog pairing essential for gametogenesis. Though processive dynein motility requires binding to an activating adaptor, the identity of the activating adaptor required for dynein to move meiotic chromosomes is unknown. We show that the meiosis-specific nuclear-envelope protein KASH5 is a dy",{"id":104,"funder":7,"programme":8,"title":105,"piName":106,"institution":107,"country":74,"year":13,"amount":14,"abstract":14},"openalex-european-research-council-award-stg-grantuniglass-no-714692","Fully Suspended Nano-beams for Quantum Fluids","Ilya Golokolenov","Institut Néel",{"id":109,"funder":7,"programme":8,"title":110,"piName":111,"institution":73,"country":74,"year":13,"amount":14,"abstract":112},"openalex-european-research-council-award-erc-stg-2019-dynamecs","Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs","Pascale Gilardi‐Hebenstreit","The hallmarks of the alveolar subclass of rhabdomyosarcoma are chromosomal translocations that generate chimeric PAX3-FOXO1 or PAX7-FOXO1 transcription factors. Overexpression of either PAX-FOXO1s results in related cell transformation in animal models. Yet, in patients the two structural genetic aberrations they derived from are associated with distinct pathological manifestations. To assess the mechanisms underlying these differences, we generated isogenic fibroblast lines expressing either PA",{"id":114,"funder":7,"programme":8,"title":115,"piName":116,"institution":117,"country":118,"year":13,"amount":14,"abstract":119},"openalex-european-research-council-award-erc-stg-sbs-3-5-758843","Toward compact high-efficiency grating couplers for visible wavelength photonics","Joe A. Smith","University of Bristol","GB","Although grating couplers have become the de-facto standard for optical access to integrated silicon photonics platforms, their performance at visible wavelengths, in moderate index contrast platforms such as silicon nitride, leaves significant room for improvement. In particular, the index contrast governs the diffraction efficiency per grating tooth and the resulting overall coupler length. In this work, we develop two approaches to address this problem: a dielectric grating that sums multiple",{"id":121,"funder":7,"programme":8,"title":122,"piName":123,"institution":124,"country":101,"year":13,"amount":14,"abstract":125},"openalex-european-research-council-award-stg-785005","The spatial heterogeneity of cloud phase observed by satellite","Adam B. Sokol","University of Washington","We conduct a global assessment of the spatial heterogeneity of cloud phase within the temperature range where liquid and ice can coexist. Single-shot CALIOP lidar retrievals are used to examine cloud phase at the 333-m scale, and heterogeneity is quantified according to the frequency of switches between liquid and ice along the satellite's path. In the global mean, heterogeneity is greatest from -15 to -2C with a peak at -4C, when small patches of ice are prevalent within liquid-dominated clouds",{"id":127,"funder":7,"programme":8,"title":128,"piName":129,"institution":130,"country":101,"year":13,"amount":14,"abstract":131},"openalex-european-research-council-award-erc-stg-716424-case","Improved homological stability for certain general linear groups","Jeremy Miller","Purdue University West Lafayette","We prove that the general linear groups of the integers, Gaussian integers, and Eisenstein integers satisfy homological stability of slope 1 when using Z [ 1 \u002F 2 ] $\\mathbb {Z}[{\\nicefrac{1}{2}}]$ -coefficients and of slope 2 \u002F 3 ${\\nicefrac{2}{3}}$ when using Z $\\mathbb {Z}$ -coefficients.",{"id":133,"funder":7,"programme":8,"title":134,"piName":135,"institution":136,"country":74,"year":13,"amount":14,"abstract":14},"openalex-european-research-council-award-majoris-erc-2019-stg-850925","Distributed algorithms for scalable proximity operator computation and application to video denoising","Émilie Chouzenoux","CentraleSupélec",{"id":138,"funder":7,"programme":8,"title":139,"piName":140,"institution":73,"country":74,"year":13,"amount":14,"abstract":141},"openalex-european-research-council-award-no-716931-gestimage-erc-2016-stg","Structural Brain Asymmetries for Language: A Comparative Approach across Primates","Adrien Meguerditchian","Humans are the only species that can speak. Nonhuman primates, however, share some ‘domain-general’ cognitive properties that are essential to language processes. Whether these shared cognitive properties between humans and nonhuman primates are the results of a continuous evolution [homologies] or of a convergent evolution [analogies] remain difficult to demonstrate. However, comparing their respective underlying structure—the brain—to determinate their similarity or their divergence across spe",{"id":143,"funder":7,"programme":8,"title":78,"piName":79,"institution":80,"country":81,"year":13,"amount":14,"abstract":82},"openalex-european-research-council-award-erc-2017-stg-756489",{"id":145,"funder":7,"programme":8,"title":146,"piName":147,"institution":148,"country":149,"year":13,"amount":14,"abstract":150},"openalex-european-research-council-award-erc-stg-853045","Destructive coastal sea level oscillations generated by Typhoon Maysak in the Sea of Japan in September 2020","Jadranka Šepić","University of Split","HR","Typhoon Maysak (Julian in the Philippines) was a powerful tropical cyclone that strongly impacted coastal regions of the Sea of Japan on 2-4 September 2020. Destructive winds, violent storm waves, and intense rainfall occurred in Japan, on the Korean Peninsula, and in Far-Eastern Russia. Devastating coastal floods caused severe damage to coastal infrastructure and to ships and boats anchored in harbours and were responsible for numerous deaths. Our study indicates that the main reason for the de",{"id":152,"funder":7,"programme":8,"title":153,"piName":14,"institution":154,"country":12,"year":13,"amount":155,"abstract":156},"cordis-european-research-council-award-101039716","Mycorrhizal Types and Soil Carbon Storage:  A mechanistic theory of fungal mediated soil organic matter cycling in temperate forests","UNIVERSITAT BAYREUTH","€1,499,930","The world's soils are the largest terrestrial reservoir of organic carbon (C). Feedbacks between soil organic C and atmospheric CO2 will determine the future trajectory of climate change. However, predictions are largely uncertain because we still lack fundamental knowledge of the complex interplay between plants and microorganisms and its influence on C turnover. Most terrestrial plants live in symbiosis with mycorrhizal fungi. Previous work suggests that on a global scale soil C stocks are lin",{"id":158,"funder":7,"programme":8,"title":159,"piName":14,"institution":160,"country":161,"year":13,"amount":162,"abstract":163},"cordis-european-research-council-award-101040798","Cargo-towing Highly enantioselective Electro-pumps: unconventional asymmetrIc Readout and transmission of chiral information","UNIVERSITA DEGLI STUDI DI MILANO","IT","€1,492,004","Chirality is found throughout nature, but it occupies a special place in chemistry, perhaps for historical reasons, but mainly as a result of the beneficial properties of chiral molecules across a diverse range of areas, from medicine to materials science. The global aim of CHEIR is to achieve with unprecedented efficiency the propagation of chiral information along different length scales, based on the synergy of well-chosen molecular ingredients and physicochemical engineering. The artificial ",{"id":165,"funder":7,"programme":8,"title":166,"piName":14,"institution":167,"country":12,"year":13,"amount":168,"abstract":169},"cordis-european-research-council-award-101040023","Microbiota-T cell interactions - antigen-specificity and regulation in health and disease","UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN","€1,500,000","The microbiota has an enormous influence on human health. CD4+ T cells play a central role in controlling the interaction with the microbiota. By specifically reacting against individual microbial species, T cells enable a mutualistic co-existence with microbes. Inappropriate T cell responses against microbes are in turn associated with inflammatory diseases. Thus, the combination of T cell specificity and functionality form the key determinant for physiological versus pathological host-microbio",{"id":171,"funder":7,"programme":8,"title":172,"piName":14,"institution":173,"country":74,"year":13,"amount":174,"abstract":175},"cordis-european-research-council-award-101039226","An integrated theory of deciding and acting","UNIVERSITE MARIE ET LOUIS PASTEUR","€1,290,180","How do we translate information from sensory inputs and memory stores into goal-directed actions? In the last 40 years, the fields of cognitive psychology and cognitive neuroscience have focused on the decision-making stage, and very few attempts have been made to understand the complete process. The aim of the present scientific proposal is to elaborate an integrated computational theory of deciding and acting in humans, which explains conflicting measurements from these traditionally separate ",{"id":177,"funder":7,"programme":8,"title":178,"piName":14,"institution":179,"country":180,"year":13,"amount":181,"abstract":182},"cordis-european-research-council-award-101041000","Breaking through: The Impact of Turbulence on the Gas-Liquid Interface","NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU","NO","€2,320,575","A rigorous understanding of the role of turbulence, with its wide range of scales and phenomena, on mass transport across a gas-liquid interface (GLI) is one of the remaining challenges in fluid mechanics. Its importance is illustrated by considering that nearly 50% of anthropogenic CO2 is driven into the oceans by a turbulent process we do not fully understand. We know that turbulence modifies the topology of the GLI from both the liquid and gas sides, but due to the complexity of the problem, ",{"id":184,"funder":7,"programme":8,"title":185,"piName":14,"institution":186,"country":35,"year":13,"amount":168,"abstract":187},"cordis-european-research-council-award-101039196","Certified Refinement Types","FUNDACION IMDEA SOFTWARE","Refinement types are a type-based, static verification technique designed to be practical. They enrich the types of an existing programming language with logical predicates to specify program properties and automatically validate these specifications using SMT solvers. Refinement types are a promising verification technology that in the last decade has spread to mainstream languages (e.g., Haskell, C, Ruby, Scala, and the ML-family) to verify sophisticated properties of real world applications, ",{"id":189,"funder":7,"programme":8,"title":190,"piName":14,"institution":191,"country":35,"year":13,"amount":192,"abstract":193},"cordis-european-research-council-award-101042702","Interactions with Future Reach-Through Volumetric Displays","UNIVERSIDAD PUBLICA DE NAVARRA","€1,495,965","Displays in the shape of televisions, computer screens or phones are ever present in our education, work and entertainment. However, they do not take full advantage of our inner spatial abilities that we have to interact with the real world. True 3D displays can provide the same visual clues as the real world without forcing the users to wear devices. However, with State of the art (SoA) displays, the users cannot reach inside the display volume to directly interact with the virtual objects as t",{"id":195,"funder":7,"programme":8,"title":196,"piName":14,"institution":197,"country":61,"year":13,"amount":198,"abstract":199},"cordis-european-research-council-award-101041475","Effect of linguistic experience on metacognition in language tasks and transfer to non-linguistic behaviour","UNIVERSIDADE DE COIMBRA","€1,499,058","This project explores metacognitive monitoring: the ability of individuals to track decisions, cognitive states, and behavior in uncertain situations. In earlier studies, I showed that Basque-Spanish bilinguals outperform monolinguals in metacognitive efficiency in tasks that engage cognitive processes activated when we hear natural speech. I suggested that bilinguals estimate the likelihood of making an error in language tasks better than monolinguals, i.e., they have enhanced error-monitoring ",{"id":201,"funder":7,"programme":8,"title":202,"piName":14,"institution":203,"country":12,"year":13,"amount":204,"abstract":205},"cordis-european-research-council-award-101041029","Interactive and Explainable Human-Centered AutoML","GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER","€1,459,763","Trust and interactivity are key factors in the future development and use of automated machine learning (AutoML), supporting developers and researchers in determining powerful task-specific machine learning pipelines, including pre-processing, predictive algorithm, their hyperparameters and--if applicable--the architecture design of deep neural networks. Although AutoML is ready for its prime time after it achieved impressive results in several machine learning (ML) applications and its efficien",{"id":207,"funder":7,"programme":8,"title":208,"piName":14,"institution":209,"country":74,"year":13,"amount":210,"abstract":211},"cordis-european-research-council-award-101042572","Light elements in the core","EUROPEAN SYNCHROTRON RADIATION FACILITY","€2,067,194","Since the discovery of the Earth’s internal structure and the existence of a dense metallic core about a century ago, the idea of iron being the dominant component of the core gained firm support confirmed by cosmochemical and geochemical observations, seismic data, the theory of geomagnetism, and high-pressure studies. However, although closely matching, the velocities of seismic waves traveling through the core are significantly slower than those in a pure iron-nickel alloy. The observed core ",{"id":213,"funder":7,"programme":8,"title":214,"piName":14,"institution":215,"country":12,"year":13,"amount":14,"abstract":216},"cordis-european-research-council-award-101042439","Coherent Spintronic Networks for  Neuromorphic Computing","RHEINLAND-PFALZISCHE TECHNISCHE UNIVERSITAT","Neuromorphic computing uses networks of artificial neurons highly interconnected by artificial synapses to perform vast data processing tasks with unmatched efficiency, as needed, for instance, for pattern recognition or autonomous driving tasks. The synaptic connections play a paramount role to create better hardware realizations of these networks. However, it is very complex to realize large interconnectivity by electronic circuitry. COSPIN overcomes this connectivity constraint by using the e",{"id":218,"funder":7,"programme":8,"title":219,"piName":14,"institution":220,"country":221,"year":13,"amount":222,"abstract":223},"cordis-european-research-council-award-101043159","Towards a New Theory of Optimal Dynamic Graph Algorithms","TEL AVIV UNIVERSITY","IL","€1,400,000","Dynamic graph algorithms are of increasing critical importance. They are crucial for coping with dynamic networks, which model the ever-changing physical world, and have been instrumental in achieving numerous major breakthroughs in static graph algorithms.The holy grail in the field of dynamic graph algorithms has been to design algorithms with poly-logarithmic (in the input size) update time. However, recent exciting developments, in which the PI has played a central role, aim to push the upda",{"id":225,"funder":7,"programme":8,"title":226,"piName":14,"institution":227,"country":221,"year":13,"amount":228,"abstract":229},"cordis-european-research-council-award-101041159","Complex Exciton Dynamics in Materials: a First-Principles Computational Approach","WEIZMANN INSTITUTE OF SCIENCE","€1,700,000","Understanding the energetics and dynamics of excited states formed by light-matter interactions is essential for applications across optoelectronics and photophysics. In systems of reduced dimensionality, strongly-bound excitons serve as the main energy carriers, with long diffusion and relaxation lifetimes. As exciton dynamics are coupled to optical selection rules that stem from the atomic structure, enhanced exciton transport efficiency can be achieved through local structural modifications, ",{"id":231,"funder":7,"programme":8,"title":232,"piName":14,"institution":233,"country":88,"year":13,"amount":168,"abstract":234},"cordis-european-research-council-award-101040254","Understanding the melting dynamics in turbulent flows","UNIVERSITEIT TWENTE","Dissolving, eroding, and melting processes are ubiquitous in everyday life, nature, science, and technology. The challenge is to accurately predict the melting or dissolution rate e.g. of an iceberg or glacier---relevant for climate change---or of solid reactants in chemical reactors, important to accurately control reaction rates and temperatures. Current predictions for the melting of glaciers are often off by a factor of 100, and different melting models show inconsistencies. No general conse",{"id":236,"funder":7,"programme":8,"title":237,"piName":14,"institution":238,"country":239,"year":13,"amount":240,"abstract":241},"cordis-european-research-council-award-101042427","Modeling causes of language change and conservatism","UNIVERSITEIT GENT","BE","€1,172,500","Universally, human language changes over time. One fundamental assumption about language change is that it originates at the level of an individual as a shift in frequencies with which a particular variant of linguistic expression is chosen over another. Conceiving of language change as the loss of an equilibrium in a system of stochastically used grammatical options, a change presupposes an emerging disturbing factor or a cause. A change can then be viewed as an adaptation process whereby in a ",{"id":243,"funder":7,"programme":8,"title":244,"piName":14,"institution":245,"country":12,"year":13,"amount":228,"abstract":246},"cordis-european-research-council-award-101041799","Neuronal basis of group cooperation and social ties in monkeys and humans","DEUTSCHES PRIMATENZENTRUM GMBH","The negative impact on society's mental health by social distancing during the current COVID-19 pandemic highlights the importance of social interactions in maintaining a healthy life. Reputation, cooperation, and an individual's social ties play a crucial role in social interactions. My proposal will examine the interdependence and neural correlates of these psychological processes. I hypothesize that a social tie's strength influences cooperative behavior; similarly, cooperative behavior foste",{"id":248,"funder":7,"programme":8,"title":249,"piName":14,"institution":250,"country":161,"year":13,"amount":251,"abstract":252},"cordis-european-research-council-award-101039655","The Experience of Poverty in the Post-Industrial Economy","UNIVERSITA COMMERCIALE LUIGI BOCCONI","€1,393,425","The reduction of poverty is of societal importance. After advances in the study of poverty in the late 20th century, however, most high-income countries have settled on an annual measure of household income as their primary measure of poverty. In contrast, ExpPov argues that shifting socio-economic conditions in recent decades necessitate a new conceptual approach for understanding poverty and a new methodological framework for the collection of data related to the experience of poverty. Specifi",{"id":254,"funder":7,"programme":8,"title":255,"piName":14,"institution":256,"country":239,"year":13,"amount":257,"abstract":258},"cordis-european-research-council-award-101043213","The European Data Union: European Security Integration through Database Interoperability","VRIJE UNIVERSITEIT BRUSSEL","€1,499,750","EU policy-makers are constructing a European Data Union. Its ambition is database interoperability with information stored in autonomous databases becoming interconnected and available to authorities across Europe. However, database interoperability is not a mere technical fix, but an inherently political process. In the design of existing and future databases lays the foundations of future European security integration and the redefinition of some of its core dimensions: security practices, ins",{"id":260,"funder":7,"programme":8,"title":261,"piName":14,"institution":262,"country":221,"year":13,"amount":263,"abstract":264},"cordis-european-research-council-award-101039914","The Complexity of Dynamic Matrix Problems","THE HEBREW UNIVERSITY OF JERUSALEM","€1,439,413","Modern data analysis and optimization rely on our ability to process rapidly evolving dynamic datasets, often involving matrix operations in very high dimensions. Dynamic data structures enable fast information-retrieval on these huge databases by maintain- ing implicit information on the underlying data. As such, understanding the power and limitations of dynamic (matrix) data structures is a fundamental question in theory and practice. Despite decades of research, there are still very basic dy",{"id":266,"funder":7,"programme":8,"title":267,"piName":14,"institution":268,"country":12,"year":13,"amount":269,"abstract":270},"cordis-european-research-council-award-101041499","Integrable Probability","UNIVERSITAET LEIPZIG","€1,083,750","This project is devoted to integrable probability. The key feature of the field is the prominent role of methods and ideas from other parts of mathematics (such as representation theory, combinatorics, integrable systems, and others) which are applied to stochastic models. This philosophy often leads to very precise limit theorems which seem to be inaccessible by more standard probabilistic techniques.The proposed research is a study of a variety of probabilistic models. Specific examples includ",{"id":272,"funder":7,"programme":8,"title":273,"piName":14,"institution":274,"country":221,"year":13,"amount":275,"abstract":276},"cordis-european-research-council-award-101039913","Parameterized Complexity Through the Lens of Path Problems","BEN-GURION UNIVERSITY OF THE NEGEV","€1,499,821","Nowadays, numerous problems are known to be NP-hard, and hence unlikely to admit worst-case efficient algorithms. Fortunately, the field of Parameterized Complexity (PC) shows that the nutshell of hardness often lies in particular properties (called parameters) of the instances. Here, we answer the fundamental question: What makes an NP-hard problem hard? Specifically, how do different parameters of an NP-hard problem relate to its inherent difficulty? Based on this knowledge, we design efficien",{"id":278,"funder":7,"programme":8,"title":279,"piName":14,"institution":280,"country":281,"year":13,"amount":168,"abstract":282},"cordis-european-research-council-award-101042183","Subtype as a key to reduce heterogeneity of treatment effects in major depressive disorder","KAROLINSKA INSTITUTET","SE","Major depressive disorder (MDD) is a leading contributor to disability and suicide. It is the most costly brain disorder in Europe. Although multiple treatments are of proven efficacy, individual responses to treatments vary considerably and MDD recurrence is common. There is considerable motivation to improve treatment regimen for individuals with MDD. However, it has been challenging because of the fundamental lack of understanding about the causes of variable treatment outcomes. MDD is widely",{"id":284,"funder":7,"programme":8,"title":285,"piName":14,"institution":286,"country":35,"year":13,"amount":287,"abstract":288},"cordis-european-research-council-award-101039754","Controlling chirality in atomically thin quantum electronic materials","UNIVERSIDAD DE SALAMANCA","€1,799,250","Chirality is a foundational and unifying topic in science. It relates properties of elementary particles, to those of molecules in chemistry and biology (e.g. sugars), as well as the electromagnetic responses of artificial systems with non-superimposable mirror images. Besides, chirality bears an extraordinary potential for modern engineering, despite of the current lack of large, robust and actively controlled chiral signals needed to develop new applications.  The emergence of atomically thin ",{"id":290,"funder":7,"programme":8,"title":291,"piName":14,"institution":292,"country":74,"year":13,"amount":293,"abstract":294},"cordis-european-research-council-award-101039272","Domestication and adaptation in Neotropical palms: a microevolutionary history","INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT","€1,560,742","Amazonia is the most diverse forest on earth but it is facing a significant biodiversity loss due to increasing human pressures and climate change. However, the state of diversity in lowland Amazonia and underlying evolutionary processes are largely under-documented, making it difficult to anticipate future changes and to elaborate knowledge-driven mitigation strategies. Moreover, very little attention has been paid to the recent evolution of plant populations through the Holocene that witnessed",{"id":296,"funder":7,"programme":8,"title":297,"piName":14,"institution":298,"country":161,"year":13,"amount":299,"abstract":300},"cordis-european-research-council-award-101042625","Anosognosia and delusions in the diseased brain","UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA","€1,213,888","Why is the diseased human brain able to produce false beliefs that persist despite evidence to the contrary? Unawareness of neurological disturbances (anosognosia) and Delusions are examples of such false beliefs. Both have productive, narrative features. Both have been independently linked to processes involved in self-reflection, metamemory, and error-monitoring. Despite their phenomenological similarities, the research investigating their mechanisms has progressed independently. UnaWireD will",{"id":302,"funder":7,"programme":8,"title":303,"piName":14,"institution":304,"country":12,"year":13,"amount":305,"abstract":306},"cordis-european-research-council-award-101041207","Next Generation Laconic Cryptography","CISPA - HELMHOLTZ-ZENTRUM FUR INFORMATIONSSICHERHEIT GGMBH","€1,482,690","Communication efficiency is one of the central challenges for cryptography. Modern distributed computing techniques work on large quantities of data, and critically depend on keeping the amount of information exchanged between parties as low as possible. However, classical cryptographic protocols for secure distributed computation cause a prohibitive blow-up of communication in this setting.Laconic cryptography is an emerging paradigm in cryptography aiming to realize protocols for complex tasks",{"id":308,"funder":7,"programme":8,"title":309,"piName":14,"institution":310,"country":54,"year":13,"amount":311,"abstract":312},"cordis-european-research-council-award-101043198","Bridging the Games Research-Practice Gap through Theory Translation","IT-UNIVERSITETET I KOBENHAVN","€1,471,056","How can theory inform design practice? This question is among the grand challenges in both Human-Computer Interaction (HCI) and games research. Despite numerous efforts to bridge the research-practice gap, the two poles seem irreconcilable. Instead of a robust and generalizable knowledge base to tackle foundational problems around technology use, cumulative knowledge building is impeded by weak empirical studies and rampant theoretical misconceptions. Instead of providing practitioners with usef",{"id":314,"funder":7,"programme":8,"title":315,"piName":14,"institution":316,"country":35,"year":13,"amount":317,"abstract":318},"cordis-european-research-council-award-101041399","Artificial intelligence for synthetic functional genomics of blood","FUNDACIO CENTRE DE REGULACIO GENOMICA","€1,499,653","Our abilities to predict and engineer complex biological systems are in their infancy. In the context of gene regulation, we cannot design artificial promoters with specificity to arbitrary cell states, and we cannot arbitrarily trans- and de-differentiate somatic cells, although such abilities would be of high biotechnological and biomedical value. To achieve these ambitious goals, we require quantitative, predictive models of gene regulatory elements (GREs) and gene regulatory networks (GRNs),",{"id":320,"funder":7,"programme":8,"title":321,"piName":14,"institution":322,"country":323,"year":13,"amount":324,"abstract":325},"cordis-european-research-council-award-101040297","Going Viral: Music and Emotions during Pandemics (1679-1919)","UNIVERSITAT FUR MUSIK UND DARSTELLENDE KUNST WIEN","AT","€1,499,379","Within day of Covid-19 reaching Europe in early 2020, music had emerged as one of the most prominent media for emotional engagement with the effects of lockdown, sickness and grief. Its remarkable primacy for expressing, navigating and shaping emotional pandemic experiences was quickly picked up by researchers and journalists who showed an immediate interest in finding evidence both for the role of music in past pandemics and for continuities across time. It quickly transpired, though, that they",{"id":327,"funder":7,"programme":8,"title":328,"piName":14,"institution":329,"country":88,"year":13,"amount":330,"abstract":331},"cordis-european-research-council-award-101039641","Digitalized Ports, Racialized Labor: Shifting Infrastructures for Work in Container Shipping","ERASMUS UNIVERSITEIT ROTTERDAM","€1,499,998","Container shipping has implications for everyone who has ever shopped in a store or online. Shipping is the backbone of the global economy. 90% of the world's goods travel by ship. The industry has a global reach and a highly diverse workforce. It is also structured by workers' nationalities, resulting in inequalities. Inequalities occur within ships, where some European workers systematically receive higher wages, and between regions, where labor conditions vary.Shipping is currently undergoing",{"id":333,"funder":7,"programme":8,"title":334,"piName":14,"institution":160,"country":161,"year":13,"amount":335,"abstract":336},"cordis-european-research-council-award-101039762","Hamiltonian Dynamics, Normal Forms and Water Waves","€1,268,106","KAM and normal form methods are very powerful tools for analyzing the dynamics of nearly integrable finite dimensional Hamiltonian systems. In the last decades, the extension of these methods to infinite dimensional systems, like Hamiltonian PDEs (partial differential equations), has attracted the interest of many outstanding mathematicians like Bourgain, Craig, Kuksin, Wayne and many others. These techniques provide some tools for describing the phase space of nearly integrable PDEs. More preci",{"id":338,"funder":7,"programme":8,"title":339,"piName":14,"institution":262,"country":221,"year":13,"amount":340,"abstract":341},"cordis-european-research-council-award-101040660","Decoding the Multi-facets of Cellular Identity from Single-cell Data","€1,484,125","Advances in technologies that measure gene expression at single-cell resolution have revolutionized our understanding of the heterogeneity, structure and dynamics of tissues and whole organisms in health and disease. Yet, in most single-cell experiments tissue structure, temporal trajectories, and their underlying mechanisms are lost or not directly accessible. Despite experimental advances, major gaps remain in understanding how tissues orchestrate multicellular functions. In recent years, we a",{"id":343,"funder":7,"programme":8,"title":344,"piName":14,"institution":238,"country":239,"year":13,"amount":345,"abstract":346},"cordis-european-research-council-award-101039795","Digital twins for understanding forest disturbances and recovery from space","€1,498,859","Forests worldwide are undergoing large-scale and unprecedented changes in terms of structure and species composition due to anthropogenic disturbances, climate change and other global change drivers. Climate, disturbances and forest structure are all closely linked: changes in climate can lead directly to physical changes in forest structure and vice versa or to an anticipated increase in forest disturbances. However, it is still uncertain how forest structure is impacted by disturbances (locall",{"id":348,"funder":7,"programme":8,"title":349,"piName":14,"institution":350,"country":88,"year":13,"amount":351,"abstract":352},"cordis-european-research-council-award-101039904","Exiled Empiricists:  American Philosophy and the Great Intellectual Migration","TILBURG UNIVERSITY- UNIVERSITEIT VAN TILBURG","€1,493,680","In the 1930s, hundreds of European academics fled to the United States, escaping the quickly deteriorating political situation on the continent. Among them were a few dozen philosophers from a variety of different schools: logical empiricists, phenomenologists, and critical theorists. Especially the first group would have a tremendous impact on American philosophy. Although the local intellectual climate had been dictated by distinctively American traditions such as pragmatism, U.S. philosophers",{"id":354,"funder":7,"programme":8,"title":355,"piName":14,"institution":197,"country":61,"year":13,"amount":356,"abstract":357},"cordis-european-research-council-award-101040850","Microwave Fingerprinting Artificial Molecular Motors in Virtual Isolation","€1,856,793","MiCRoARTiS is the blueprint for a five-year program of frontier research to develop a sophisticated spectroscopic approach to study artificial molecular motors. The ultimate goal will be to demonstrate the harnessing of conformational dynamics of molecular motors in the gas phase using microwave spectroscopy. My recent research has shown we can measure broadband microwave spectra of molecular motors in idle mode. Such achievement was remarkable not only because rotationally resolved studies of m",{"id":359,"funder":7,"programme":8,"title":360,"piName":14,"institution":361,"country":180,"year":13,"amount":362,"abstract":363},"cordis-european-research-council-award-101040948","The Micro-Level Effects of Civil Wars on Multiple Dimensions of Women's Empowerment","UNIVERSITETET I BERGEN","€1,784,229","WarEffects aims to advance a systematic, nuanced, and rigorous understanding of how civil wars affect women’s social and political empowerment at the local level. Recent quantitative research suggests that civil wars promote women’s political representation, but these accounts reflect country-level aggregate measures and often focus on a minority of political ‘elite’ women. Thus, they do not inform us how subnational and individual-level variation in civil war experiences affect the majority of ",{"id":365,"funder":7,"programme":8,"title":366,"piName":14,"institution":367,"country":161,"year":13,"amount":368,"abstract":369},"cordis-european-research-council-award-101039657","Using CARDIac simulations to run in-silicO clinical TRIALS","GRAN SASSO SCIENCE INSTITUTE","€1,499,423","Clinical trials are a key tool for advancing medical knowledge, but they consist of a long and costly process entailing the recruitment of a representative cohort of participants to properly account for the population statistical variability. Computational engineering is a promising approach to gain more insight into patients' cardiac pathologies and to test innovative medical devices before running conclusive in-vivo experiments on animals or medical trials on humans. This technological breakth",{"id":371,"funder":7,"programme":8,"title":372,"piName":14,"institution":373,"country":161,"year":13,"amount":374,"abstract":375},"cordis-european-research-council-award-101039206","Autobiographical memory, time and environmental navigation: unveiling the cognitive map of our past through an integrated neuropsychological perspective","UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA","€1,499,718","Episodic autobiographical memory refers to the ability to recollect and re-experience events of our own life that occurred at a particular time and place. It allows for the development and maintenance of our unique personal identity and self-awareness, namely autonoetic consciousness. An integrated and comprehensive model of how and where episodic autobiographical memories are stored in the human brain is still lacking. The core hypothesis of ATENA is that previous experiences are spatially orga",{"id":377,"funder":7,"programme":8,"title":378,"piName":14,"institution":379,"country":74,"year":13,"amount":380,"abstract":381},"cordis-european-research-council-award-101040822","Understanding and fighting inequity in education: breaking the cycle between socioeconomic disadvantage, low confidence, and resignation.","UNIVERSITE PARIS DAUPHINE","€1,455,750","Equity in education is a central and long-standing concern of countries around the world. Despite significant amounts of public resources invested over several decades towards disadvantaged children, the relationship between education outcomes and personal circumstances remains persistently strong in most countries. The objectives of my project EMANCIPATE is to make progress in our understanding of why there is such persistent social inequity in education. I will explore a new channel: perceptio",{"id":383,"funder":7,"programme":8,"title":384,"piName":14,"institution":385,"country":12,"year":13,"amount":386,"abstract":387},"cordis-european-research-council-award-101039438","Network Synergies in Tissue Homeostasis and Stromal Prevention of Inflammatory Disease.","UNIVERSITATSKLINIKUM ERLANGEN","€1,499,514","Inflammation has evolved to protect us from the outside world. However, in doing so, it consumes large amounts of energy and causes collateral damage, thus requiring strict control on multiple levels. While the mechanisms that govern inflammation once ongoing are well defined, we lack basic knowledge of the processes that regulate its actual onset in vivo. Only by understanding the mechanisms that orchestrate tissue stress responses and defend against unwanted inflammation will we pave the way f",{"id":389,"funder":7,"programme":8,"title":390,"piName":14,"institution":391,"country":12,"year":13,"amount":392,"abstract":393},"cordis-european-research-council-award-101039452","Winds ANd Disk structures near and Afar","EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE","€1,437,941","When and how did the multitude of observed exo-planets form? The WANDA project aims at tackling this central question by investigating the origin of the ring-like and asymmetric structures observed  in protoplanetary disks, the cradle of planets, and pushing such studies to the distant and massive star-forming regions, the locations that best represent the natal environments of the known exo-planets. The WANDA team will employ a novel multi-wavelength and multi-technique observational approach, ",{"id":395,"funder":7,"programme":8,"title":396,"piName":14,"institution":397,"country":398,"year":13,"amount":399,"abstract":400},"cordis-european-research-council-award-101041554","Storage of Electrons into Chemical Bonds: Towards Molecular Solar Electrical Batteries","USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.","CZ","€1,449,034","While photovoltaics has observed rapid growth in the last decades and utilization of solar energy becomes ever growing part of the total electricity produced by mankind, the lack of control over electrical output caused by fluctuation of solar irradiance is an inevitable drawback of the mass use of solar cells. Solar batteries, addressing intermittent production of solar energy, offer an elegant solution without the need of electricity transport and redistribution. In most examples solar cells a",{"id":402,"funder":7,"programme":8,"title":403,"piName":14,"institution":404,"country":12,"year":13,"amount":405,"abstract":406},"cordis-european-research-council-award-101041376","Hebrew Philosophical Manuscripts as Sites of Engagement","UNIVERSITY OF HAMBURG","€1,495,013","In the Middle Ages, philosophical activity undertaken in Hebrew was not conducted within an institutionalized environment. There were no universities, regulated curricula, or professors, but only small circles of scholars, most of whom we know nothing about. These scholars had to obtain their own copies of the works they wished to explore, sometimes even copying them themselves or with the help of others. Heavily involved in the production of the materials they were using, they often interfered ",{"id":408,"funder":7,"programme":8,"title":409,"piName":14,"institution":329,"country":88,"year":13,"amount":410,"abstract":411},"cordis-european-research-council-award-101042662","Complex Contagion of Childcare Strategies amongst Low-Income Parents","€1,470,130","Background - High quality childcare greatly improves outcomes in later life. Yet childcare access and usage are distributed unevenly, leading to amplified inequalities in later life outcomes. Parents from low-income households are 50% less likely to use formal childcare services than high-income households and use them when the child is older and less intensely. Research has shown that cost, location, and quality of childcare effects usage, yet policy solutions aimed at removing these barriers h",{"id":413,"funder":7,"programme":8,"title":414,"piName":14,"institution":415,"country":323,"year":13,"amount":416,"abstract":417},"cordis-european-research-council-award-101039572","German Arithmetical Treatises in Manuscripts of the Late Middle Ages (1400-1522). A Study on Philology, History and Culture based on a Digital Edition of the Treatises.","UNIVERSITAET INNSBRUCK","€1,489,506","How was the practice of arithmetic developed and spread during the transition between the Middle Ages and the Modern Period? We know a lot about the evolution of mathematical theory and its diffusion in Latin, but little about the way in which arithmetic knowledge spread in the vernaculars in the 15th and early 16th centuries. Translation and adaptation of arithmetic treatises and manuals provided access to mathematical knowledge for new groups of people, shaped the practices of reckoning, and o",{"id":419,"funder":7,"programme":8,"title":420,"piName":14,"institution":421,"country":281,"year":13,"amount":14,"abstract":422},"cordis-european-research-council-award-101042148","Plant based 4D biohybrid systems","LINKOPINGS UNIVERSITET","Modern technology relies on fully artificial systems. While in many cases these systems are high performing there have been approaches to add further complexity or intelligence inspired by natural processes. Biomimetic systems however are purely synthetic and cannot fully mimic the high complexity of living systems.The overall goal of the 4D-PhytoHybrid is to develop photosynthetic biohybrid systems that maintain fundamental properties of the living components and set the foundation for the deve",{"id":424,"funder":7,"programme":8,"title":425,"piName":14,"institution":426,"country":161,"year":13,"amount":427,"abstract":428},"cordis-european-research-council-award-101040302","The German Network. Primo Levi's Correspondence with German Readers and Intellectuals","UNIVERSITA DEGLI STUDI DI FERRARA","€1,190,125","Primo Levi (1919-1987), one of the most important witnesses of the Holocaust, has been studied increasingly over the last three decades. Levi is currently recognized as one of the few Italian thinkers of essential importance for the understanding of the 20th century as a whole. The LeviNeT project aims to provide the very first edition of a significant portion of Levi?s multilingual correspondence. The edition will be open source and hosted on an online platform. It will concentrate on Levi?s Ge",{"id":430,"funder":7,"programme":8,"title":431,"piName":14,"institution":432,"country":88,"year":13,"amount":14,"abstract":433},"cordis-european-research-council-award-101040729","FIrst NEar-TErm ApplicationS of QUAntum Devices","UNIVERSITEIT LEIDEN","Quantum technologies have set remarkable milestones in the last years, e.g. with quantum advantage experiments and loophole-free Bell tests. Despite this progress, the quantum devices we currently have, the so-called noisy, intermediate-scale quantum (NISQ) devices, are too imperfect to run textbook quantum algorithms, yet they hold great potential. With their advent, much research has been devoted to finding them a first practical application. Focus on optimization, quantum chemistry and machin",{"id":435,"funder":7,"programme":8,"title":436,"piName":14,"institution":437,"country":438,"year":13,"amount":14,"abstract":439},"cordis-european-research-council-award-101042147","Patents, Bioethics and the Human Body:  Reconceptualising Bioethics in Patent Decision-Making and the Governance Function of Patents","NATIONAL UNIVERSITY OF IRELAND MAYNOOTH","IE","PatentsInHumans challenges the current marginalisation of bioethics in patent decision-making for technologies related to the human body. A patent gives a rightsholder the right to stop others using a patented technology. This allows them to control how that technology is provided, to whom, and on what terms. Where patents are for technologies related to the body, this control poses considerable bioethical issues because patents can affect how we treat, use and modify bodies. Yet patent systems ",{"id":441,"funder":7,"programme":8,"title":442,"piName":14,"institution":443,"country":323,"year":13,"amount":168,"abstract":444},"cordis-european-research-council-award-101041551","Development and Evolution of Tetrapod Motor Circuits","INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA","A hallmark of the nervous system is its rich cell-type diversity, its intricate connectivity and its coordinated patterns of activity. Behavior largely is an emergent property of this complexity. Thus, to understand behavior, we must define neurons’ molecular, cellular and functional properties. This task has proven especially challenging for motor circuits with their readily apparent output in motor activity but astonishingly heterogeneous populations of neurons. To parse this complexity, I pro",{"id":446,"funder":7,"programme":8,"title":447,"piName":14,"institution":350,"country":88,"year":13,"amount":448,"abstract":449},"cordis-european-research-council-award-101042069","Welfare, redistribution and financial stability in housing and mortgage markets","€1,494,124","Worldwide, housing wealth represents the most important asset in households' balance sheet, and mortgage debt is the most important liability. In the past two decades, several countries have experienced house price bubbles, excessive households' leverage, and increasing risk-taking behavior of banks. To limit these phenomena, and in response to the 2008 financial crisis, new regulations have been introduced in housing and mortgage markets. The lack of disaggregate and extensive micro level data ",{"id":451,"funder":7,"programme":8,"title":452,"piName":14,"institution":453,"country":88,"year":13,"amount":168,"abstract":454},"cordis-european-research-council-award-101040682","Functional Measurements IN-THE-KIDNEY to Diagnose, Understand and Treat Renal Tubulopathies","STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM","BACKGROUND | Renal tubulopathies are a large group of genetic disorders that disturb the function of the kidney tubule. A major challenge for diagnostics and treatment of magnesium (Mg2+) wasting tubulopathies, is absence of functional cell models and tools to study the pathophysiology. Diagnostics of hereditary Mg2+ wasting tubulopathies based on genetic screening, rather than biological measurements of kidney processes. Therapy largely depends on oral supplements because therapeutics that targ",{"id":456,"funder":7,"programme":8,"title":457,"piName":14,"institution":458,"country":61,"year":13,"amount":459,"abstract":460},"cordis-european-research-council-award-101041788","The Afterlives of Development Interventions in Eastern Africa (Kenya, Tanzania, Mozambique)","Iscte - Instituto Universitário de Lisboa","€1,499,745","International development involves ideologies and activities ostensibly directed towards the improvement of well-being of populations in the Global South. Mainstream development interventions emphasize forward-looking ideas of progress and advocate for novelty. In so doing, however, the sector is often myopic, as evidenced by countless unintended consequences that stretch beyond interventions' official life cycle. Whether deemed success or failure, such interventions leave behind a long trail of",{"id":462,"funder":7,"programme":8,"title":463,"piName":14,"institution":464,"country":74,"year":13,"amount":465,"abstract":466},"cordis-european-research-council-award-101039756","Exotic High Energy Phenomenology","UNITED NATIONS EDUCATIONAL SCIENTIFIC AND CULTURAL ORGANIZATION","€1,351,125","The Standard Model (SM) of particle physics is a very elegant theory that has led to a long list of impressive achievements, one of the latest being the discovery of the Higgs particle. Nowadays, the researchers of the phenomenology at the highest energy frontier face the unknown, and one of the biggest questions in the field is: what physics lies beyond the SM? Progress in answering this question will require the combined efforts of a large number of experimental and theoretical physicists.How ",{"id":468,"funder":7,"programme":8,"title":469,"piName":14,"institution":464,"country":74,"year":13,"amount":470,"abstract":471},"cordis-european-research-council-award-101039794","Computational Hardness Of RepresentAtion Learning","€1,280,750","Rich internal representations of complex data are crucial to the predictive power of neural networks. Unfortunately, current statistical analyses are restricted to over-simplified networks, whose representations (i.e., weight matrices) are either random, and\u002For project the data in comparatively very large or very low dimensional spaces; in many applications the situation is very different. The modelisation of realistic data is another issue. There is an urgent need to reconcile theory and practi",{"id":473,"funder":7,"programme":8,"title":474,"piName":14,"institution":475,"country":281,"year":13,"amount":476,"abstract":477},"cordis-european-research-council-award-101041224","Revealing cellular behavior with single-cell multi-omics","UPPSALA UNIVERSITET","€2,499,864","Chemical reactions govern cellular behavior, and are revealed by analysis of small molecules involved in intracellular metabolism. Individual cells in biological systems continuously adapt to improve survival and biological function, making them chemically and behaviorally heterogeneous. Unraveling this heterogeneity is essential to realize the correlation to disease state and health, but it is masked in bulk analyses of millions of cells. I propose to develop a groundbreaking analytical approac",{"id":479,"funder":7,"programme":8,"title":480,"piName":14,"institution":481,"country":12,"year":13,"amount":168,"abstract":482},"cordis-european-research-council-award-101042339","Moving Russia(ns): Intergenerational Transmission of Memories Abroad and at Home","ZENTRUM FUR OSTEUROPA- UND INTERNATIONALE STUDIEN (ZOIS)","Children of migrants are exposed to two national histories: those told in their country of residence and those relating to their family?s homeland. However, it remains unclear how the intergenerational transmission of historical views shapes the relationship migrants cultivate with ?here? and ?there?. Applying theories of intergenerational transmission and second-generation transnationalism, MoveMeRU addresses this urgent gap and compares the historical memories of migrants and non-migrants acro",{"id":484,"funder":7,"programme":8,"title":485,"piName":14,"institution":486,"country":12,"year":13,"amount":487,"abstract":488},"cordis-european-research-council-award-101040724","Melding behavioural ecology and biomaterials research to track the evolution of mechanical super-performance of spider silk composites","UNIVERSITAET GREIFSWALD","€1,788,003","Many organisms assemble biological materials into architectures and tools that add and extend biological functions - with profound ecological effects, and inspiring human technologies. However, there is no general concept of how evolutionary bio-material innovation arises from both the physiological and the behavioural recombination of compounds. SuPerSilk aims to understand how mechanical super-performance evolves by disentangling the concerted effects of both physiological and behavioural fact",{"id":490,"funder":7,"programme":8,"title":491,"piName":14,"institution":492,"country":35,"year":13,"amount":493,"abstract":494},"cordis-european-research-council-award-101039048","Gaseous detectors for neutrino physics at the European Spallation Source","FUNDACION DONOSTIA INTERNATIONAL PHYSICS CENTER","€1,496,205","The recent detection of the coherent elastic neutrino-nucleus scattering (CEnNS) opens the possi- bility of using neutrinos to explore physics beyond the Standard Model deploying small detectors. However, the CEnNS process generates signals at the few keV level, requiring very sensitive detection technologies. The European Spallation Source (ESS) has been identified as an optimal source of low energy neutrinos offering an opportunity to explore at depth the physics of CEnNS, with large discovery",{"id":496,"funder":7,"programme":8,"title":497,"piName":14,"institution":498,"country":161,"year":13,"amount":499,"abstract":500},"cordis-european-research-council-award-101040227","Winds in galaxies","SCUOLA NORMALE SUPERIORE","€1,199,519","Massive black holes (BHs) reside at the center of galaxies and release an extraordinary amount of energy during their accretion phase. Such energy drives galaxy-scale gas outflows that can significantly influence the evolution of the host galaxy. Despite the remarkable theoretical and observational progress in quantifying the energetics and dynamics of such outflows, establishing their role during the formation and evolution of galaxies remains a long-standing problem in modern astrophysics.  WI",{"id":502,"funder":7,"programme":8,"title":503,"piName":14,"institution":504,"country":12,"year":13,"amount":14,"abstract":505},"cordis-european-research-council-award-101040439","The Structure of Normativity","UNIVERSITAET BIELEFELD","Some of the core fields of philosophy – including moral philosophy, value theory, and epistemology – are, at their heart, concerned with normative questions: questions about what is good or bad, right or wrong, justified or unjustified. These questions concern the content of judgements that human beings are constantly making and that structure our way of thinking, feeling, and acting. But while there is wide agreement in contemporary philosophy that normative judgements form a unified and import",{"id":507,"funder":7,"programme":8,"title":508,"piName":14,"institution":154,"country":12,"year":13,"amount":14,"abstract":509},"cordis-european-research-council-award-101039399","Sustainable Solid State Sodium Batteries","The Li-ion battery, developed in the last 30 years, is a very successful technology. However, it now faces the challenge of powering the e-mobility revolution, requiring a large increase of raw resources availability. At this point in history, given the roadmap of the European Green Deal and the need to reduce CO2 emissions, such a scale up should be seen as a unique opportunity to eliminate unsustainable elements from the batteries. Yet the Li-ion battery relies on a series of elements that are",{"id":511,"funder":7,"programme":8,"title":512,"piName":14,"institution":513,"country":12,"year":13,"amount":168,"abstract":514},"cordis-european-research-council-award-101040188","Funding Frictions after the Global Financial Crisis","FRANKFURT SCHOOL OF FINANCE & MANAGEMENT GEMEINNUTZIGE GMBH","Funding frictions are tensions in financial markets that can preclude institutions from borrowing money or rolling over debt. In extreme situations, such as the 2007-2009 global financial crisis (GFC) or the market turmoil in March 2020 during the Covid-19 pandemic, funding frictions can lead to the default of otherwise healthy institutions and destabilize the entire financial system. While earlier research (pre-GFC) tends to disregard funding frictions, the enormous risk associated with these m",{"id":516,"funder":7,"programme":8,"title":517,"piName":14,"institution":518,"country":519,"year":13,"amount":520,"abstract":521},"cordis-european-research-council-award-101040122","Inequality-aware Market Design","FUNDACJA ADEPTOW I MILOSNIKOW EKONOMII","PL","€1,191,561","Policymakers often introduce rules constraining transactions in individual markets—such as rent control—or even choose to distribute scarce resources by circumventing markets completely, as is frequently the case for health care or transit. Yet, traditional economic intuition opposes these sorts of policies because—unlike well-functioning markets—they introduce allocative inefficiency.In this project, I will explore the optimal design of marketplaces in the presence of underlying inequalities be",{"id":523,"funder":7,"programme":8,"title":524,"piName":14,"institution":262,"country":221,"year":13,"amount":257,"abstract":525},"cordis-european-research-council-award-101041711","Understanding Deep Learning","While extremely successful, deep learning (DL) still lacks a solid theoretical foundation.In the last 5 years the PI focused almost entirely on DL theory, yielding a strong publication record with 7 papers at NeurIPS (the leading ML conference), including 2 spotlights (top 3% of submitted papers) and one oral (top 1%), 2 papers at ICLR (the leading DL conference), and 1 paper at COLT (the leading ML theory conference). These results are amongst the first that break a 20 years hiatus in NN theory",{"id":527,"funder":7,"programme":8,"title":528,"piName":14,"institution":529,"country":12,"year":13,"amount":530,"abstract":531},"cordis-european-research-council-award-101039524","It's about time: Towards a dynamic account of natural vision.","UNIVERSITAET OSNABRUECK","€1,499,455","The visual world around us is a source of rich semantic information that guides our higher-level cognitive processes and actions. To tap into this resource, the brain?s visual system engages in complex, intertwined computations to actively sample, extract, and integrate information across space and time. Surprisingly however, the integrative nature of vision hardly plays a role in the way we approach it in experimentation and computational modelling. Instead, higher-level vision is commonly trea",{"id":533,"funder":7,"programme":8,"title":534,"piName":14,"institution":535,"country":12,"year":13,"amount":536,"abstract":537},"cordis-european-research-council-award-101040688","Two-dimensional Dipolar Quantum Gases: Fluctuations and Orders.","RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG","€1,498,500","Ordering in two-dimensional (2D) worlds is fundamentally different from what we know in 3D: Thermal fluctuations preclude conventional long-range order. An unconventional ordering mechanism based on topological defects may occur. The resulting order is topological, remains fluctuating, and intimately depends on the interparticle interactions. Many systems, including frustrated magnets, superconductors, colloids, and quantum gases, exhibit such orders. Their topological origin confers them exotic",{"id":539,"funder":7,"programme":8,"title":540,"piName":14,"institution":350,"country":88,"year":13,"amount":541,"abstract":542},"cordis-european-research-council-award-101039648","The Agency of Transnational Strategic Litigators in Global Governance","€1,470,849","Litigators feature in a crucial role as we confront the pressing global environmental governance challenges of the 21st Century. They possess an agency which is capable of driving the evolution and implementation of law across national boundaries and at the supranational level. This project proposes to develop a groundbreaking, explanatory model of transnational collaborations among strategic litigators which accounts for their modes of collaboration, how those collaborations affect their agency",{"id":544,"funder":7,"programme":8,"title":545,"piName":14,"institution":546,"country":161,"year":13,"amount":547,"abstract":548},"cordis-european-research-council-award-101043003","Investigating the Molecular identity of PAcemaker neurons in CorTical development","UNIVERSITA HUMANITAS","€1,490,000","Spontaneous activity is a prominent feature of the immature brain. Even before birth and in absence of stimuli, neurons organize in networks and spontaneously generate correlated activity. While spontaneous dynamics in the cerebral cortex have long been overlooked and considered just as epiphenomena, recent clinical data on preterm infants and preclinical studies have spurred a renewed interest for this early electrical activity. However, appreciation of the role of spontaneous activity during t",{"id":550,"funder":7,"programme":8,"title":551,"piName":14,"institution":316,"country":35,"year":13,"amount":552,"abstract":553},"cordis-european-research-council-award-101042103","Dissecting the role of sperm transcriptome dynamics in intergenerational inheritance through native RNA nanopore sequencing","€1,499,428","Mammalian sperm RNA is increasingly recognized as an additional source of paternal hereditary information beyond DNA. Environmental inputs, such as diet and stress, can reshape the sperm RNA signature and induce offspring phenotypes that relate to paternal environmental stressors. However, how, when and to what extent sperm RNA populations change, and what is the role that RNA modifications and other post-transcriptional regulatory layers play in shaping sperm RNA dynamics, remains poorly unders",{"id":555,"funder":7,"programme":8,"title":556,"piName":14,"institution":160,"country":161,"year":13,"amount":557,"abstract":558},"cordis-european-research-council-award-101039651","Rebuilding the foundations of planet formation: proto-planetary disc evolution","€1,495,755","With thousands of exoplanets known, we have truly entered the exoplanet era. Explaining the huge diversity of observed exoplanetary systems remains however a big challenge. The only way we have to study planet formation is to study the environments in which they form, proto-planetary discs: to understand planets, we have to understand discs and the physical processes happening in them.The field of proto-planetary discs is currently being shaken by the crumbling of viscous theory, the traditional",{"id":560,"funder":7,"programme":8,"title":561,"piName":14,"institution":280,"country":281,"year":13,"amount":562,"abstract":563},"cordis-european-research-council-award-101041484","Tracing virus-specific CD8+ T cell clonotype zonation and function in humans","€1,499,932","The current Covid-19 pandemic highlights the need to gain better understanding of precise mechanisms that enable immune control of viral infections. Although it is established that CD8+ T cells are required to suppress viremia, most view these cells simply as ?killer T cells? based almost exclusively on studies of blood. I recently discovered that efficient immune control of HIV is mediated primarily by non-killer resident memory CD8+ T cells, whereas CD8+ T cells with high ?killer instinct? are",{"id":565,"funder":7,"programme":8,"title":566,"piName":14,"institution":567,"country":323,"year":13,"amount":568,"abstract":569},"cordis-european-research-council-award-101039320","Metabolic Gut Inflammation in Crohn's disease","MEDIZINISCHE UNIVERSITAT INNSBRUCK","€1,493,875","The rising incidence of inflammatory bowel diseases such as Crohn?s disease (CD) has become a global health care issue in the 21st century. The complex genetic underpinning is increasingly appreciated, while environmental cues and specifically a Western diet are suspected to impact development and course of disease. Mechanistic insights that would support this assumption remain scarce and specific nutrients that trigger a flare are unknown. Westernisation of dietary habits is partly characterise",{"id":571,"funder":7,"programme":8,"title":572,"piName":14,"institution":573,"country":323,"year":13,"amount":574,"abstract":575},"cordis-european-research-council-award-101041435","Quantum Applications with Rydberg Atom Arrays","OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN","€1,397,300","Rydberg atoms arrays have emerged as a promising platform for assembling quantum matter in a bottom-up approach. This platform combines deterministically prepared, reconfigurable arrays of individually trapped cold atoms with strong, coherent interactions enabled by excitation to atomic Rydberg states and in situ state readout. It enables a scalable realization of quantum spin models with system sizes beyond what can be simulated on classical computers. The main goal of this project is to harnes",{"id":577,"funder":7,"programme":8,"title":578,"piName":14,"institution":397,"country":398,"year":13,"amount":579,"abstract":580},"cordis-european-research-council-award-101041374","Non-canonical RNA caps - cellular reaction to environment and stress","€1,497,425","The goal of this project is to understand the role of non-canonical RNA caps (mainly dinucleoside polyphosphates = NpnNs) in prokaryotes and eukaryotes. The 5' termini of the RNA are critical structures and are the least characterized among RNA modifications. In this project, we will develop selective capturing techniques for identification of NpnN-RNA sequences and identify the interacting partners of NpnN-RNA. Furthermore, we will reveal their metabolism and their role in cellular reaction to ",{"id":582,"funder":7,"programme":8,"title":583,"piName":14,"institution":203,"country":12,"year":13,"amount":584,"abstract":585},"cordis-european-research-council-award-101039556","Revealing second messenger functions in bacterial stress response,  cell differentiation and natural product biosynthesis","€1,478,373","Sophisticated signalling systems enable bacteria to occupy almost every single niche on our planet. In such systems, second messengers are crucial information carriers that elicit cellular adaptation to diverse signals. Current dynamics in signalling research have led to the discovery of an exquisite collection of nucleotides that bacteria use as second messengers, including cyclic dimeric adenosine monophosphate (c-di-AMP). A unique feature of c-di-AMP is its essentiality, making it an attracti",{"id":587,"funder":7,"programme":8,"title":588,"piName":14,"institution":373,"country":161,"year":13,"amount":589,"abstract":590},"cordis-european-research-council-award-101040600","Hydromechanical coupling in tectonic faults and the origin of aseismic slip, quasi-dynamic transients and earthquake rupture","€1,462,710","Earthquakes and tectonic fault slip are among the most hazardous and unpredictable natural phenomena. Fluids play a key role in tectonic faulting and recent research suggests that fluids are central in both human induced seismicity and the mode of fault slip, ranging from episodic tremor and slip to slow earthquakes. However, the lack of accessibility to earthquake faults and the complexity of physical processes has limited our ability to develop holistic models for hydromechanical coupling in f",{"id":592,"funder":7,"programme":8,"title":593,"piName":14,"institution":594,"country":74,"year":13,"amount":168,"abstract":595},"cordis-european-research-council-award-101041069","Access to crop diversity and small farms’ resilience to climate variability in African drylands: The role of seed and information networks","CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC","Crop diversity is a key resource for smallholder farmers in drylands, as it plays a major role in their resilience by stabilizing crop production in the face of climate variability. Although access to crop diversity is pivotal for these farmers, the processes driving access are not fully understood. Previous research indicates that access to crop diversity may rely on the social networks through which crop seeds and information are diffused. These networks display a wide diversity of patterns, i",{"id":597,"funder":7,"programme":8,"title":598,"piName":14,"institution":599,"country":221,"year":13,"amount":600,"abstract":601},"cordis-european-research-council-award-101039928","Deciphering Gene Regulatory Networks governing Mammalian Sex Determination","BAR ILAN UNIVERSITY","€1,651,868","During mammalian sex determination, the bipotential embryonic gonad adopts either testicular or ovarian cell fates. This process highly relies on precise expression of several pro-male versus pro-female factors, most of which are transcription factors (TFs) and signalling pathway components. Yet, we still do not understand the interplay and hierarchy among these factors, their direct target genes, the regulatory elements they bind to, nor do we have an in vitro system to address these questions.",{"id":603,"funder":7,"programme":8,"title":604,"piName":14,"institution":605,"country":281,"year":13,"amount":606,"abstract":607},"cordis-european-research-council-award-101042878","Towards materials at extremes: from intense dynamic compression to expansion","KUNGLIGA TEKNISKA HOEGSKOLAN","€1,496,873","The project aims at developing robust, reliable and effective techniques for generation of extreme conditions. Positive TPa as well as negative MPa pressures in liquids will be produced with limited resources available in everyday research environment.The project offers a unique integration of approaches and resources in high voltage engineering and plasma physics applications towards classical problems of compressible fluid mechanics. It investigates by experiment, computation and theory the ma",{"id":609,"funder":7,"programme":8,"title":610,"piName":14,"institution":611,"country":61,"year":13,"amount":612,"abstract":613},"cordis-european-research-council-award-101042912","Genetic factors Enabling Microbiome Symbioses: Bees as a natural model system","FUNDACAO GIMM - GULBENKIAN INSTITUTE FOR MOLECULAR MEDICINE","€1,498,125","The gut microbiome is essential for the wellbeing of many animals including humans and bees. However, the genetic factors that enable stable, healthy microbiomes remain poorly understood. In particular, little is known about how different members of a gut microbial community communicate and interact with one another, both at the molecular level (which genes underlie the interactions) and the ecological level (how these genes are distributed across populations). Due to the complexity of most gut ",{"id":615,"funder":7,"programme":8,"title":616,"piName":14,"institution":238,"country":239,"year":13,"amount":617,"abstract":618},"cordis-european-research-council-award-101042729","Philology as Science in 19th-Century Europe","€1,464,300","Philology once defined what it meant to be scientific – and it may yet once again. Increasingly a broad array of scholars using digital methods cite the historical accomplishments of philology as a model for systematic study around unwieldy and heterogenous textual corpuses. Despite this renewed interest, there is still no systemic account for the huge range of activity and aegis, data and networks, that propelled philology to its status as a model or even the 'queen of science' in C19 Europe. I",{"id":620,"funder":7,"programme":8,"title":621,"piName":14,"institution":179,"country":180,"year":13,"amount":622,"abstract":623},"cordis-european-research-council-award-101041995","A Middle Way? Probing Sufficiency through Meat and Milk in China","€1,431,630","About one-fifth of the world's greenhouse gas emissions come from agriculture. Much of this relates to livestock used for animal-based foods. Rather than arguing for increased efficiency, MidWay probes the concept of sufficiency to explore its potential for reducing human impacts on Earth's biosphere while preserving overall welfare, i.e., its potential for defining a 'middle way' between 'too little' and 'too much'. To do this, MidWay studies the cases of meat and milk in China. While meat was ",{"id":625,"funder":7,"programme":8,"title":626,"piName":14,"institution":627,"country":221,"year":13,"amount":628,"abstract":629},"cordis-european-research-council-award-101039271","Neolithic coastal settlements and responses to environmental dynamics: A pioneering world lost beneath the Mediterranean Sea","UNIVERSITY OF HAIFA","€1,498,938","Coastal societies hold a vital place in Mediterranean history; many of their earliest trajectories, however, are archaeologically obscure due to a rise in sea levels since the last Ice Age. BEFOREtheFLOOD is based on an observation that before it was inundated, the Mediterranean littoral was extremely dynamic (e.g., formation\u002Fretreat of marshes, increased soil salinity, rapidly rising sea levels), necessitating constant reactions by its inhabitants. This project aims to study how Neolithic coast",{"id":631,"funder":7,"programme":8,"title":632,"piName":14,"institution":633,"country":35,"year":13,"amount":634,"abstract":635},"cordis-european-research-council-award-101042680","Chemical Design of Smart Molecular\u002F2D Devices for Information Technologies","UNIVERSITAT DE VALENCIA","€1,499,240","The final goal of 2D-SMARTiES is to develop a new generation of magnonic devices based on hybrid molecular\u002F2D heterostructures in which a precise control of the spin dynamics can be achieved by external manipulation of stimuli-responsive molecules. With this aim in mind, the project will establish an efficient theoretical and computational framework to guide the synthetic efforts towards the creation of low power consumption and highly tunable nanodevices for information technologies using a che",{"id":637,"funder":7,"programme":8,"title":638,"piName":14,"institution":639,"country":74,"year":13,"amount":168,"abstract":640},"cordis-european-research-council-award-101040480","Laser Activated Chemistry of Reactive Intermediates:  Direct Observation in the jet","UNIVERSITE PARIS XII VAL DE MARNE","The goal of LACRIDO is to lock reactive intermediates of a fast reaction by freezing them through Joules-Thompson expansion in the molecular jet, then precisely determine their three-dimensional (3D) structures by chirped-pulse microwave spectroscopy to capture all species marking the reaction mechanism.LACRIDO comprises two stages. The first stage focuses on the detection of van der Waals complexes of the educts through their 3D structures encoded in the microwave spectra. New results of the lo",{"id":642,"funder":7,"programme":8,"title":643,"piName":14,"institution":644,"country":161,"year":13,"amount":612,"abstract":645},"cordis-european-research-council-award-101041255","the new generation of scalable urban HEat isLand mitigatIOn by means of  adaptive photoluminescent radiative cooling Skins","UNIVERSITA DEGLI STUDI DI PERUGIA","From their early origins urbanization has produced both benefits and penalties due to the generated anthropogenic stress. Documented overheating such as urban heat island (UHI) compromises human wellbeing in cities, where 60% of the world population lives and is exposed to the related health risks and vulnerability. An urgent solution is much needed here and now, since classic passive cooling techniques showed to slowly mitigate UHI. A disruptive improvement must be dedicated to eradicate the pr",{"id":647,"funder":7,"programme":8,"title":648,"piName":14,"institution":233,"country":88,"year":13,"amount":168,"abstract":649},"cordis-european-research-council-award-101040669","Interface-sensitive Spectroscopy of Atomically-defined Solid\u002FLiquid Interfaces Under Operating Conditions","Charge-transfer reactions are key not only to the way that nature fuels life in photosynthesis but also in synthesizing sustainable fuels like hydrogen. Charge transfer occurs at interfaces with an applied potential, yet almost all our understanding of electrocatalytic activity trends comes from the bulk material properties in the as-prepared state. We still lack interface-sensitive spectroscopy tools that can probe the composition and electronic structure under reaction conditions. Only with su",{"id":651,"funder":7,"programme":8,"title":652,"piName":14,"institution":653,"country":12,"year":13,"amount":654,"abstract":655},"cordis-european-research-council-award-101040214","Deciphering commensal-host-pathogen metabolic interactions to combat intestinal infections","JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG","€1,498,750","Our intestinal tract offers an attractive environment for bacteria. The beneficial bacteria of our microbiota feast on undigested foods and provide numerous health benefits. Enteric pathogens see this environment as an entry point for infection. Both groups influence each other, creating a tripartite interaction with us, the host. Understanding this interaction represents an emerging research area to combat infections poised to improve human health. Bacteroides are key commensals in these triang",{"id":657,"funder":7,"programme":8,"title":658,"piName":14,"institution":659,"country":12,"year":13,"amount":660,"abstract":661},"cordis-european-research-council-award-101042266","Secure Execution of Smart Contracts","UNIVERSITAET DUISBURG-ESSEN","€1,486,313","Smart contracts are computer programs that autonomously execute on the blockchain. They have the potential to revolutionize many applications from finance, insurance, energy, healthcare, and production industries. However, smart contracts have become an appealing attack target. Since smart contracts are always online and easy to hack once a vulnerability is discovered, recent attacks resulted in large losses of cryptocurrency thereby questioning the benefits of this revolutionary technology. CON",{"id":663,"funder":7,"programme":8,"title":664,"piName":14,"institution":665,"country":161,"year":13,"amount":666,"abstract":667},"cordis-european-research-council-award-101043216","Infant verbal Memory in Development: a window for understanding language constraints and brain plasticity from birth","UNIVERSITA DEGLI STUDI DI PADOVA","€1,499,798","Although infants perform more poorly than adults on many cognitive tasks, they are more competent language learners. Newborns must have access to an exceptional processing system where bits of the -inherently transient- speech signal remain encoded to build knowledge of the language around them. Memory, the ability to hold information in mind that is no longer present in the environment, is one of the most important components of this machinery. As yet, however, what characterizes the first cogn",{"id":669,"funder":7,"programme":8,"title":670,"piName":14,"institution":665,"country":161,"year":13,"amount":671,"abstract":672},"cordis-european-research-council-award-101040025","Synthetic Bimodal Photoredox Catalysis:  Unlocking New Sustainable Light-Driven Reactivity","€1,920,260","Solar light is an inexhaustible, abundant, and free reactant that can promote the construction and transformation of molecules. The chemistry community is particularly interested in photocatalysis, which uses light energy to promote a chemical transformation. Photocatalysts (PCs) play a key role in transformative light-driven processes by donating or receiving electrons to or from the target substrate. The selection and structural refinement of PCs can channel reactivity to diverse mechanistic p",{"id":674,"funder":7,"programme":8,"title":675,"piName":14,"institution":676,"country":35,"year":13,"amount":677,"abstract":678},"cordis-european-research-council-award-101042610","Common Envelope Transients - Progenitors, Precursors, and Properties of their Outbursts","UNIVERSITAT DE BARCELONA","€1,489,225","Common envelope evolution (CEE) is a crucial phase in binary evolution, as it is responsible for the formation of many of the most exciting systems in astrophysics, including sources of gravitational waves. Despite its importance, there are several unanswered questions that hamper the urgently needed progress in this field: What systems enter CEE? What happens during CEE? How the CEE remnants evolve? Recently, a new type of astrophysical transients called luminous red novae (LRNe) has emerged as",{"id":680,"funder":7,"programme":8,"title":681,"piName":14,"institution":682,"country":519,"year":13,"amount":168,"abstract":683},"cordis-european-research-council-award-101040164","Chirality-sensitive Nuclear Magnetoelectric Resonance","UNIWERSYTET WARSZAWSKI","This project lifts the blindness of nuclear magnetic resonance (NMR) spectroscopy to molecular chirality. First, we will observe chirality-sensitive magnetoelectric effects. Based on these effects, a new branch of molecular spectroscopy (abbreviated as NMER) is proposed, which will enable us to identify enantiomers directly without requiring chemical shift reagents or chiral solvents. Direct chiral NMR effects are very small and have not been previously detected, but this proposal will utilize s",{"id":685,"funder":7,"programme":8,"title":686,"piName":14,"institution":682,"country":519,"year":13,"amount":687,"abstract":688},"cordis-european-research-council-award-101042989","Ultracold polyatomic molecules for controlled chemistry and precision physics","€1,499,125","Ultracold atoms have been successfully used in quantum simulations and precision measurements. Molecules possess a richer internal structure promising new applications. However, only relatively simple molecules have been produced and employed at ultralow temperatures. This project aims to understand and harness the increasing complexity of ultracold polyatomic molecules to probe the fundamentals of chemistry and physics.We will extend the range of ultracold polyatomic molecules and their applica",{"id":690,"funder":7,"programme":8,"title":691,"piName":14,"institution":682,"country":519,"year":13,"amount":692,"abstract":693},"cordis-european-research-council-award-101040152","Masters of the stone: The stonecutters' workshops and the rise of the late antique epigraphical cultures (third-fifth century AD)","€1,499,625","The STONE-MASTERS project aims at exploring one of the most startling problems in the global history of research on collective memory and commemorative practices - the transformation of Roman Imperial epigraphic traditions in the later 3rd c. AD, and the subsequent rise of the so-called epigraphic cultures of Late Antiquity. The problem has been passionately debated since the 1980s, but so far no definite conclusions have been reached. In this project, the PI argues that the main reason for the ",{"id":695,"funder":7,"programme":8,"title":696,"piName":14,"institution":697,"country":12,"year":13,"amount":698,"abstract":699},"cordis-european-research-council-award-101040726","Decoding diabetic kidney disease","UNIVERSITAETSKLINIKUM AACHEN","€1,783,319","Diabetic kidney disease (DKD) is a rapidly growing worldwide health problem and represents one of the most serious threats in current medicine. DKD is the most common cause of chronic kidney disease (CKD) with 20% of DKD patients progressing to end-stage renal disease, which is associated with tremendously increased morbidity and mortality. The pathophysiology of DKD is complex, incompletely understood and the number of treatment options is low. The vision of DECODE-DKD is to utilize a patient-c",{"id":701,"funder":7,"programme":8,"title":702,"piName":14,"institution":703,"country":323,"year":13,"amount":704,"abstract":705},"cordis-european-research-council-award-101042570","Reconstructing Paleolithic Population Dynamics Using Microstratified Paleogenomic Analysis","UNIVERSITAT WIEN","€1,460,604","Modern humans are defined and sustained by interactions and networks. In Paleolithic contexts, reconstructing interactions and networks is limited to inferences based on material culture or direct evidence of biological relatedness, but evidence on the latter in the form of human fossils is very rare. Still, archaeogenetic research can formulate supra-regional models for broad time periods based on only a few genomes by distinguishing ancient clades, but not to the level of interactions between ",{"id":707,"funder":7,"programme":8,"title":708,"piName":14,"institution":709,"country":12,"year":13,"amount":710,"abstract":711},"cordis-european-research-council-award-101041677","Tandem Repeats Associated with Neurogenomic Somatic Instability and Neurodegeneration","DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV","€1,495,557","Dementia and other neurodegenerative diseases are among the leading causes of disability worldwide and have an immense societal impact due to lack of effective treatments. For developing better preventive and therapeutic strategies, it is essential to clarify their still largely elusive genetic basis and pathophysiology. Emerging insights from the study of rare hereditary repeat expansion disorders caused by elongations of repetitive DNA sequences (tandem repeats (TRs)) indicate that TRs could i",{"id":713,"funder":7,"programme":8,"title":714,"piName":14,"institution":682,"country":519,"year":13,"amount":715,"abstract":716},"cordis-european-research-council-award-101040160","A MISTery of Long Secondary Periods in Pulsating Red Giants - Traces of Exoplanets?","€1,380,760","Exoplanetary science is one of the most studied and challenging areas of modern astrophysics. Various planet detection techniques allowed astronomers to discover over 4,500 extrasolar planets in our Galaxy, providing important constraints for testing planet formation theories.However, with the currently available methods, it is still impossible to find planets in the far regions of the Milky Way and in other galaxies. In consequence, we still cannot answer fundamental questions of exoplanetary s",{"id":718,"funder":7,"programme":8,"title":719,"piName":14,"institution":432,"country":88,"year":13,"amount":720,"abstract":721},"cordis-european-research-council-award-101039296","The Social Dilemma of Self-Reliance","€1,499,984","To tackle global challenges like climate change or pandemics, large-scale cooperation is needed. Cooperation and its maintenance are traditionally seen as a conflict between pro-sociality (dedicating resources towards public goods) and free-riding (taking advantage of the cooperation of others). Yet, when faced with shared problems that require cooperation, individuals may also have the ability to solve them individually. Societies often, and increasingly so, provide individuals with means to be",{"id":723,"funder":7,"programme":8,"title":724,"piName":14,"institution":725,"country":221,"year":13,"amount":168,"abstract":726},"cordis-european-research-council-award-101039986","Highly Energy-Efficient Resistive Switching in Defect- and Strain- Engineered Mott Insulators for Neuromorphic Computing Applications","TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY","The pressing need for beyond-von-Neumann computing paradigms has triggered intensive efforts into understanding and controlling various resistive switching (RS) mechanisms. This switching, in which the two terminal resistance of a device is controlled by current is at the heart of emerging technologies such as resistive random access memory and neuromorphic computation. These technologies promise to revolutionize artificial neural networks and mimic the behavior of biological brains, triggering ",{"id":728,"funder":7,"programme":8,"title":729,"piName":14,"institution":725,"country":221,"year":13,"amount":168,"abstract":730},"cordis-european-research-council-award-101041250","Deep Bayesian Reinforcement Learning -- Unifying Perception, Planning, and Control","For robots to assist humanity in homes, or hospitals, the capability to manipulate diverse objects is imperative. So far, however, robotic manipulation technology has struggled in managing the uncertainty and unstructuredness that characterize human environments.Machine learning is a natural approach -- the robot can adapt to a given scenario, even if it was not programmed to handle it beforehand. Indeed, Deep Reinforcement Learning (deep RL), which has recently led to AI breakthroughs in comput",{"id":732,"funder":7,"programme":8,"title":733,"piName":14,"institution":734,"country":12,"year":13,"amount":168,"abstract":735},"cordis-european-research-council-award-101040907","Symmetry and Optimization at the Frontiers of Computation","RUHR-UNIVERSITAET BOCHUM","Noncommutative group optimization is a powerful emerging paradigm, which has already led to the solution of outstanding problems in computational complexity, algebra, and statistics. Pioneered by the PI and collaborators, it generalizes convex optimization from Euclidean space to the far more general setting of curved spaces with symmetries. Its unfamiliar kind of convexity has recently received much attention in statistics and machine learning. The symmetries are realized by noncommutative grou",{"id":737,"funder":7,"programme":8,"title":738,"piName":14,"institution":739,"country":398,"year":13,"amount":740,"abstract":741},"cordis-european-research-council-award-101039303","Next-Generation Natural Language Generation","UNIVERZITA KARLOVA","€1,420,375","This project aims to overcome the major hurdles that prevent current state-of-the-art models for natural language generation (NLG) from real-world deployment.While deep learning and neural networks brought considerable progress in many areas of natural language processing, neural approaches to NLG remain confined to experimental use and production NLG systems are handcrafted. The reason for this is that despite the very natural and fluent outputs of recent neural systems, neural NLG still has ma",{"id":743,"funder":7,"programme":8,"title":744,"piName":14,"institution":745,"country":12,"year":13,"amount":168,"abstract":746},"cordis-european-research-council-award-101041453","Ocean Glow: Controls on ocean productivity using ocean fluorescence detected from space","HELMHOLTZ-ZENTRUM FUR OZEANFORSCHUNG KIEL (GEOMAR)","Primary production in the ocean is critically important for human wellbeing - it regulates atmospheric carbon dioxide as well as sustaining almost all ocean life. But models predicting the impacts of climate change do not agree on the sign of ocean primary production in the coming century. Currently, satellite observations tell us how ocean primary productivity is changing, but not the underlying controls. Fieldwork and modelling show nutrient limitation is key, but there is currently no way to ",{"id":748,"funder":7,"programme":8,"title":749,"piName":14,"institution":750,"country":239,"year":13,"amount":168,"abstract":751},"cordis-european-research-council-award-101040088","Formalizing, Verifying and Applying ISA Security Guarantees as Universal Contracts","KATHOLIEKE UNIVERSITEIT LEUVEN","The Instruction Set Architecture (ISA) is the interface that processor hardware offers to software developers. Current ISAs do not explicitly specify the security properties guaranteed by that interface, so that, for example, recent severe micro-architectural side-channel vulnerabilities like Spectre did not even violate the specifications. This project proposes a fundamentally new approach to specify ISA security properties by using what we call universal contracts. These are formal contracts i",{"id":753,"funder":7,"programme":8,"title":754,"piName":14,"institution":750,"country":239,"year":13,"amount":755,"abstract":756},"cordis-european-research-council-award-101042343","Scientific societies and the globalization of science (1930-1990)","€1,446,500","Science has become a global enterprise. To produce knowledge, scientists with different nationalities, gender backgrounds, ethnicities and socio-political views engage in debate and adopt shared codes of conduct (e.g. leaving out personal bias when evaluating each other’s work). This project conducts historical research into the mechanisms that structure these global social relations within science by using 20th century scientific societies as its lens. It hypothesizes that these hitherto unstud",{"id":758,"funder":7,"programme":8,"title":759,"piName":14,"institution":750,"country":239,"year":13,"amount":760,"abstract":761},"cordis-european-research-council-award-101040049","Towards a Systematic Theory of Aristotelian Diagrams in Logical Geometry","€1,437,776","Aristotelian diagrams, such as the square of opposition, have been widely used throughout the history of philosophy and logic. Nowadays, they also have several applications in other disciplines that are concerned with logical reasoning, such as psychology, linguistics and computer science. However, many of the applications of Aristotelian diagrams suffer from substantial problems, often due to a lack of understanding of the intricate logical properties of these diagrams. Consequently, the tremen",{"id":763,"funder":7,"programme":8,"title":764,"piName":14,"institution":765,"country":35,"year":13,"amount":692,"abstract":766},"cordis-european-research-council-award-101040046","Chemical rewiring of E3 ubiquitin ligases as a generalizable therapeutic approach","FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)","Classical drug design relies mostly on the availability of accessible pockets to block specific protein activities. Despite tremendous progress, more than 80% of all human proteins remain beyond the reach of traditional inhibitor-centric approaches. Chemical ablation of protein abundance using bivalent degraders (PROTACs) moves away from an occupancy-driven (inhibition) to an event-driven (binding) pharmacology. However, their design is intrinsically limited to targets that are ligandable via ch",{"id":768,"funder":7,"programme":8,"title":769,"piName":14,"institution":770,"country":398,"year":13,"amount":771,"abstract":772},"cordis-european-research-council-award-101040057","2D sandwiches, artificial layered building blocks for multifunctional materials","FYZIKALNI USTAV AV CR, VVI","€1,975,955","The possibility to create new materials bottom-up was enhanced via the stacking of atomically thin layers of two-dimensional (2D) materials with van der Waals interactions (vdWIs). Unfortunately, the downside of vdWIs is the, in general, weak electronical and mechanical interaction between the individual layers. This hinders the creation of multiferroic materials working at ambient conditions, which are despite extensive research still very scarce, from stacked layers with vdWIs.This research ai",{"id":774,"funder":7,"programme":8,"title":775,"piName":14,"institution":725,"country":221,"year":13,"amount":168,"abstract":776},"cordis-european-research-council-award-101039436","Algorithmic Bias Control in Deep learning","Deep Learning (DL) has reached unparalleled performance in many domains. However, this impressive performance typically comes at the cost of gathering large datasets and training massive models, requiring extended time and prohibitive costs. Significant research efforts are being invested in improving DL training efficiency, i.e., the amount of time, data, and resources required to train these models, by changing the model (e.g., architecture, numerical precision) or the training algorithm (e.g.",{"id":778,"funder":7,"programme":8,"title":779,"piName":14,"institution":238,"country":239,"year":13,"amount":780,"abstract":781},"cordis-european-research-council-award-101040024","Black Hole Horizons in Quantum Gravity","€1,497,050","The project Black Hole Horizons in Quantum Gravity aims for an in-depth investigation of black holes and the information paradox in the context of quantum gravity. Due to the recent breakthroughs in astronomy, these exotic objects have moved from the purely theoretical realm to being abundant in our physical universe. Surprisingly, our theoretical understanding of them is insufficient to even in principle understand their horizons and what happens behind them. Our approach to tackle these questi",{"id":783,"funder":7,"programme":8,"title":784,"piName":14,"institution":250,"country":161,"year":13,"amount":14,"abstract":785},"cordis-european-research-council-award-101042055","Education, Diversity, Innovation, and Politics","The introduction of free and universal education, accessible to diverse religious and cultural groups, has been a major achievement worldwide and a crucial factor for economic development. However, still today, many countries do not guarantee full access to education, religious minorities often face restricted learning opportunities, and top educational institutions are being dismantled if they dissent from governments' policies.    The over-arching goal of EDIPO is to study these extremely impo",{"id":787,"funder":7,"programme":8,"title":788,"piName":14,"institution":220,"country":221,"year":13,"amount":789,"abstract":790},"cordis-european-research-council-award-101042417","Secrecy-Preserving Proofs with Solid Foundations","€1,390,625","The traditional notion of a proof offers no secrecy --- proving the validity of a blockchain transaction would reveal its details, proving qualification for a loan would reveal private financial information, and proving that a system has been hacked could reveal sensitive details about the system. Remarkably, using cryptography, this problem can be solved. Secrecy-preserving proofs are a class of protocols allowing to prove assertions about secret information, without actually revealing the info",{"id":792,"funder":7,"programme":8,"title":793,"piName":14,"institution":725,"country":221,"year":13,"amount":794,"abstract":795},"cordis-european-research-council-award-101041208","Fast Proofs for Verifying Computations","€1,435,000","A proof-system is a protocol that enables a powerful prover to convince a weaker verifier of the validity of a computational statement. Proof-systems have been central to the theory of computing since its inception. Some of the most important results, concepts and open problems in this field revolve around notions of efficient proof-systems.In recent years, due to the surging need for large scale computation coupled with advances such as cloud computing and blockchains, these computational proof",{"id":797,"funder":7,"programme":8,"title":798,"piName":14,"institution":725,"country":221,"year":13,"amount":799,"abstract":800},"cordis-european-research-council-award-101039692","Modern Challenges in Learning Theory","€1,433,750","Recent years have witnessed tremendous progress in the field of Machine Learning (ML). Learning algorithms are applied in an ever-increasing variety of contexts, ranging from engineering challenges such as self-driving cars all the way to societal contexts involving private data. These developments pose important challenges (i) Many of the recent breakthroughs demonstrate phenomena that lack explanations, and sometimes even contradict conventional wisdom. One main reason for this is because clas",{"id":802,"funder":7,"programme":8,"title":803,"piName":14,"institution":804,"country":805,"year":13,"amount":806,"abstract":807},"cordis-european-research-council-award-101040021","Search for Milli-lenses to discriminate between dark matter models","IDRYMA TECHNOLOGIAS KAI EREVNAS","EL","€1,486,875","One of the most compelling mysteries in both cosmology and particle physics is the nature of Dark Matter (DM). We propose to investigate this problem using strong gravitational lensing of active galaxies on the key but poorly-explored milliarcsecond scales. Gravitational lensed images with angular separation on milliarcsecond scales probe gravitational lens systems where the lens is a compact object with mass in the range 10^6 - 10^9 solar masses. This mass range is particularly critical for the",{"id":809,"funder":7,"programme":8,"title":810,"piName":14,"institution":811,"country":161,"year":13,"amount":812,"abstract":813},"cordis-european-research-council-award-101041040","Sample complexity for inverse problems in PDE","UNIVERSITA DEGLI STUDI DI GENOVA","€1,153,125","This project will develop a mathematical theory of sample complexity, i.e. of finite measurements, for inverse problems in partial differential equations (PDE). Inverse problems are ubiquitous in science and engineering, and appear when a quantity has to be reconstructed from indirect measurements. Whenever physics plays a crucial role in the description of an inverse problem, the mathematical model is based on a PDE. Many imaging modalities belong to this category, including ultrasonography, el",{"id":815,"funder":7,"programme":8,"title":816,"piName":14,"institution":817,"country":239,"year":13,"amount":818,"abstract":819},"cordis-european-research-council-award-101042414","quantum electro-optic amplifiers for the next generation quantum and supercomputers","INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM","€1,930,736","Quantum computers face many bottlenecks towards upscaling the number of qubits and increasing their computational power. One of them is the radio frequency (RF) -bottleneck between the qubit processor inside the cryostat and the room temperature control and readout electronics. And like for their classical counterparts, hope lies in replacing the RF-links by optical fibers, resulting in a hybrid situation where RF-qubits will be used for computation and optical qubits will serve for remote commu",{"id":821,"funder":7,"programme":8,"title":822,"piName":14,"institution":811,"country":161,"year":13,"amount":823,"abstract":824},"cordis-european-research-council-award-101040535","The Philosophy of Experiential Artifacts","€1,493,753","Ancient Greeks used one word, techne, to designate both technical and artistic practices. It is only in modern times that art gained autonomy, becoming the object of one philosophical discipline: aesthetics. However, the emergence of mass media, and then of digital media, has brought art close to technology, challenging its autonomy. In this situation, some basic philosophical questions about art regain centrality: Why art? What is art for? What is the role of art in a technological society like",{"id":826,"funder":7,"programme":8,"title":827,"piName":14,"institution":828,"country":35,"year":13,"amount":829,"abstract":830},"cordis-european-research-council-award-101042080","Wireless Networks within Next-Generation Computing Systems","UNIVERSITAT POLITECNICA DE CATALUNYA","€1,494,889","Computing systems are ubiquitous in our daily life and have transformed the way we learn, work, or communicate with each other, to the point that progress is intimately tied to the improvements brought by new generations of the processors that lie at the heart of these systems. A common trait of current computing systems is that their internal data communication has become a fundamental bottleneck. The anticipated death of Moore’s Law has forced computer scientists and architects to find new way",{"id":832,"funder":7,"programme":8,"title":833,"piName":14,"institution":834,"country":54,"year":13,"amount":835,"abstract":836},"cordis-european-research-council-award-101043143","Dynamical Formation of Black Hole Mergers","KOBENHAVNS UNIVERSITET","€1,919,186","Gravitational wave (GW) astrophysics is bound to have an exceptional future building on the success of LIGO\u002FVirgo and propelled by the next generation of ground-based detectors (expected to see hundreds-of-thousands of GW sources per year) and space-borne observatories, such as LISA and DECIGO (that will make multi-band GW astrophysics a reality). This ERC research program will lead to new ideas and tools to probe in unprecedented ways the origin of binary black hole (BBH) mergers, with particul",{"id":838,"funder":7,"programme":8,"title":839,"piName":14,"institution":840,"country":161,"year":13,"amount":841,"abstract":842},"cordis-european-research-council-award-101041908","What Makes People Targets: A Multi-Actor Study of How Ethnic Discrimination is Perceived, Tackled and Avoided","EUROPEAN UNIVERSITY INSTITUTE","€1,499,290","Despite progressive anti-discrimination legislation and the popularity of diversity policies touted as the key to a culturally diverse workplace, discrimination of ethnic minorities in the labor market is remarkably persistent and pervasive. TARGETS integrates literature from sociology, social psychology, organization and sociolegal studies into a novel multi-actor and dynamic theoretical framework to examine what makes people targets of ethnic discrimination. Both conceptually and empirically, ",{"id":844,"funder":7,"programme":8,"title":845,"piName":14,"institution":846,"country":35,"year":13,"amount":847,"abstract":848},"cordis-european-research-council-award-101042252","Remote-Sensing Satellite Data and the Making of Global Climate in Europe, 1980s-2000s.","UNIVERSITAT AUTONOMA DE BARCELONA","€1,484,844","Answers to how to manage the urgent climate crisis depend on perceptions of global climate. Knowing how they came to be is necessary to open up new possibilities about ways to face it. CLIMASAT aims at establishing a truly comprehensive narrative that integrates various spheres of knowledge to understand how global climate discourses, policies and practices came into being in the approximate 1980s-2000s Europe.To do so, CLIMASAT substantially places the production, circulation and use of data ge",{"id":850,"funder":7,"programme":8,"title":851,"piName":14,"institution":852,"country":12,"year":13,"amount":853,"abstract":854},"cordis-european-research-council-award-101041480","Island ecosystem ecology from deep prehistory to the Anthropocene","MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV","€1,498,883","Humans are fragmenting ecosystems into habitat 'islands', causing an unprecedented global collapse of large mammal populations just as science is discovering their essential ecological roles. The impact of these losses is such that our understanding of the contemporary biosphere is clearly shaped by a world artificially depleted of terrestrial giants. However, the causes of megafaunal extinctions over a much deeper, >50,000-year timeframe remain strongly contested. How did specific anthropogenic",{"id":856,"funder":7,"programme":8,"title":857,"piName":14,"institution":858,"country":74,"year":13,"amount":859,"abstract":860},"cordis-european-research-council-award-101042293","Hydrodynamics and entropy production in low-dimensional quantum systems","CY CERGY PARIS UNIVERSITE","€1,497,850","In the past years, quantum non-equilibrium emerged as a new principal research arena, promising to assist the current development of new quantum technologies and to shine a new light on disparate fields of theoretical and experimental physics, from black holes to condensed matter and statistical physics. As quantum dynamics represents a major challenge for modern computational methods, relevant developments have come from devising new generalised and extended forms of classical hydrodynamic theo",{"id":862,"funder":7,"programme":8,"title":863,"piName":14,"institution":834,"country":54,"year":13,"amount":864,"abstract":865},"cordis-european-research-council-award-101041466","EXOplanet Diversity and the Origin of the Solar System","€1,498,943","The ongoing discovery of ever-more Earth-like exoplanets raises the question how these planets form. Answering this question requires a breakthrough in our understanding of terrestrial planet formation, since this topic has previously been studied almost exclusively in the context of the Solar System and with an emphasis on the late-stage giant-impact phase. However, recently, a window into the very earliest stages of planet formation has opened through radio observations of protoplanetary discs",{"id":867,"funder":7,"programme":8,"title":868,"piName":14,"institution":869,"country":88,"year":13,"amount":168,"abstract":870},"cordis-european-research-council-award-101041824","Human Ads: Towards Fair Advertising in Content Monetization on Social Media","UNIVERSITEIT UTRECHT","Human ads are Internet influencers who earn revenue by creating and monetizing authentic and relatable advertising content for their armies of followers, by relying on business models such as influencer and affiliate marketing. This content often results not only in commercial but also political (hidden) ads, which look the same, are posted by the same persons, are displayed in the same digital space, to the same audiences, and raise the same transparency issues. In this environment, consumers a",{"id":872,"funder":7,"programme":8,"title":873,"piName":14,"institution":874,"country":875,"year":13,"amount":876,"abstract":877},"cordis-european-research-council-award-101042052","An Ontological Reconstruction of Gaming Disorder: A Qualitative Meta-Phenomenological Foundation","JYVASKYLAN YLIOPISTO","FI","€1,986,991","Videogames have become one of the most prevalent forms of cultural production around the world. While their role in teaching and physical culture (“esports”) keeps growing, the health debates on videogame play, or gaming, culminated in 2019 with the World Health Organization’s historical decision to add “gaming disorder” to the International Classification of Diseases. This made gaming, next to gambling, the first and only cultural product with a diagnostic category of addictive use. The above e",{"id":879,"funder":7,"programme":8,"title":880,"piName":14,"institution":881,"country":28,"year":13,"amount":882,"abstract":883},"cordis-european-research-council-award-101042568","The Quantum Gravity Imprint: New Guiding Principles at Low Energies","ORGANISATION EUROPEENNE POUR LA RECHERCHE NUCLEAIRE","€1,382,625","What are the constraints that a low energy Effective Field Theory must satisfy to be consistent with a Quantum Gravity description at higher energies? Can we determine these constraints in a precise way and use them as new guiding principles to progress in High Energy Physics? Recently, novel quantum gravity criteria have been proposed that imply non-trivial constraints on models of Particle Physics and Cosmology and can provide the missing piece to solve the long-standing naturalness issues obs",{"id":885,"funder":7,"programme":8,"title":886,"piName":14,"institution":869,"country":88,"year":13,"amount":168,"abstract":887},"cordis-european-research-council-award-101042961","The evolutionary origins of human culture: a primatological perspective","Culture  the inheritance of behavioural phenotypes through social learning  is one of the most pervasive and influential characteristics of the human species. However, we lack knowledge about the origins of culture and to what extent its sub-components reflect species universals. Studying primates enables us to identify the evolutionary origins of human culture and the extent of its human uniqueness. Until now, it has largely been assumed that the social and cumulative components of human cultur",{"id":889,"funder":7,"programme":8,"title":890,"piName":14,"institution":891,"country":88,"year":13,"amount":892,"abstract":893},"cordis-european-research-council-award-101041097","Lightning corona Imaging From a radio Telescope","STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN","€2,124,988","We do not understand how lightning in our atmosphere initiates, nor how it develops and propagates after initiation. The fundamental difficulty is that these basic lightning phenomena are driven by the meter-scale dynamics of the low-conductivity plasma that surrounds the lightning channel, known as the corona, but the dynamics of this corona is as-yet unresolved. Resolving the structure of the lightning corona and how it develops in time is the holy grail of lightning science, as it will reveal",{"id":895,"funder":7,"programme":8,"title":896,"piName":14,"institution":891,"country":88,"year":13,"amount":897,"abstract":898},"cordis-european-research-council-award-101041819","Attosecond nanoscopy of electron dynamics instrongly correlated materials","€1,997,105","In 1929, one year after the formulation of his world-famous equation, Paul Dirac wrote that the fundamental laws () of a large part of physics and the whole of chemistry are thus completely known, () but lead to equations that are too complex to be solved. While Dirac was referring to analytical solutions to his equation, numerical approaches have made tremendous progress over the past century. Nonetheless, the so-called strongly correlated materials continue to defy a common experimental and co",{"id":900,"funder":7,"programme":8,"title":901,"piName":14,"institution":891,"country":88,"year":13,"amount":902,"abstract":903},"cordis-european-research-council-award-101040117","Information processing in passive elastic structures","€1,686,875","Smart devices constantly monitor the environment and analyse the resulting stream of information, waiting for wake-up events ranging from a skipped heartbeat in a pacemaker to a verbal command in an intelligent speaker. In electronic devices, such constant workload requires reliable power and leads to significant battery drainage. The aim of INFOPASS is to answer the need for zero standby power, always-on sensing and processing, by inventing novel components based on architected elastic microstr",{"id":905,"funder":7,"programme":8,"title":906,"piName":14,"institution":907,"country":875,"year":13,"amount":908,"abstract":909},"cordis-european-research-council-award-101039110","Unification of the best piezoelectric and photovoltaic properties in a single photoferroelectric material","OULUN YLIOPISTO","€1,496,023","The piezoelectric (PE) effect is the core electromechanical coupling function widely used in sensors, actuators and transducers for various industrial sectors. The photovoltaic (PV) effect produces green electricity from the solar energy. To date, materials showing strong PE and efficient PV properties are separate families of oxide perovskites and narrow band gap semiconductors, respectively. This project aims to unify these PE and PV performances by making new photoferroelectric materials. Pho",{"id":911,"funder":7,"programme":8,"title":912,"piName":14,"institution":750,"country":239,"year":13,"amount":913,"abstract":914},"cordis-european-research-council-award-101040854","Exploring Life narratives of Violence Among Refugees from Africa’s Great Lakes Region (AGLR)","€1,499,206","This project aims to map and examine to what extent, and under what conditions, the life narratives of the Africa Great Lakes Region (AGLR) refugees evolve, travel, and transform across time and space. It will explore how these narratives shape relationships among refugees and communities in countries of transition and destination. It examines how life narratives change as the  AGLR refugees encounter preconceived notions about themselves and their communities in host countries. The study will r",{"id":916,"funder":7,"programme":8,"title":917,"piName":14,"institution":891,"country":88,"year":13,"amount":918,"abstract":919},"cordis-european-research-council-award-101042416","Chasing plasma storms on exoplanets","€1,487,199","Are there other worlds out there that can sustain life? A key factor in the ability of a planet to host life is its atmosphere. Stars can erode planetary atmospheres by bombarding the planet with plasma. How well planets can protect their atmospheres depends on the strength of their magnetic fields. We do not know the ultimate fate of exoplanet atmospheres because we have neither detected massive plasma ejections on stars nor measured the magnetic fields of exoplanets. Both of these shortcomings",{"id":921,"funder":7,"programme":8,"title":922,"piName":14,"institution":852,"country":12,"year":13,"amount":923,"abstract":924},"cordis-european-research-council-award-101039090","Machine-Assisted Teaching for Open-Ended Problem Solving: Foundations and Applications","€1,495,000","Computational thinking and problem solving skills are essential for everyone in the 21st century, both for students to excel in STEM+Computing fields and for adults to thrive in the digital economy. Consequently, educators are putting increasing emphasis on pedagogical tasks in open-ended domains such as programming, conceptual puzzles, and virtual reality environments. When learning to solve such open-ended tasks by themselves, people often struggle. The difficulties are embodied in the very na",{"id":926,"funder":7,"programme":8,"title":927,"piName":14,"institution":268,"country":12,"year":13,"amount":928,"abstract":929},"cordis-european-research-council-award-101039567","Forest vulnerability to compound extremes and disturbances in a changing climate","€1,425,000","Forests play a crucial role not only in providing breathable oxygen, supporting biodiversity and regulating water and energy exchanges, but also in mitigating climate change. Currently, forests absorb 25% of human CO2 emissions, but their sequestration potential may be negated by more frequent and intense weather extremes and disturbances in the future. Mega-droughts, massive wildfires and widespread tree mortality reported in the last decade might be early warnings of the upcoming threats to fo",{"id":931,"funder":7,"programme":8,"title":932,"piName":14,"institution":852,"country":12,"year":13,"amount":168,"abstract":933},"cordis-european-research-council-award-101040759","Neural circuits for social communication","The main objective of this proposal is to understand how vocal communication is used to organize social groups and in turn how brain circuits have evolved to process social information encoded in vocal cues. The naked mole-rat, as one of only two eusocial mammals, is especially well-suited to this research question. Naked mole-rats form highly cooperative social units and like bees, wasps, and ants, live in multigenerational colonies under the control of a single breeding female, queen. In addit",{"id":935,"funder":7,"programme":8,"title":936,"piName":14,"institution":852,"country":12,"year":13,"amount":937,"abstract":938},"cordis-european-research-council-award-101040002","MANUNKIND: Determinants and Dynamics of Collaborative Exploitation","€1,497,749","Chattel slavery and other forms of collaborative exploitation are with us since ancient times, inflicting unfathomable suffering on countless generations of victims. And even though slavery is outlawed globally today, its modern-day successors continue to cause severe harm for millions.Previous research has compiled rich datasets on the prevalence of collaborative exploitation across cultures and across time. A startling gap exists in the literature, however, with respect to modeling the fundame",{"id":940,"funder":7,"programme":8,"title":941,"piName":14,"institution":852,"country":12,"year":13,"amount":923,"abstract":942},"cordis-european-research-council-award-101041982","Intrinsic autophagy receptors: identity and cellular mechanisms.","Macromolecular complexes (MC) are cellular machines that perform a wide array of vital tasks. They operate in a controlled, coordinated fashion within the crowded environment of the cell. Accumulation of dysfunctional MCs leads to age-related diseases. Despite recent technological advancements, it still remains elusive for many of them how excess or dysfunctional MCs are sensed and removed. I have recently established a role of intrinsic receptors in degradation of the nuclear pore complex and t",{"id":944,"funder":7,"programme":8,"title":945,"piName":14,"institution":852,"country":12,"year":13,"amount":654,"abstract":946},"cordis-european-research-council-award-101042421","Inferring hominin population history through space and time using introgressed haplotypes","In the last decade, ancient DNA studies have increased their throughput from single samples to thousands of genomes published every year, giving us unprecedented data about human genetic history. However, tools and methods that efficiently use this wealth of data are sorely lacking, especially because DNA extracted from fossils is often scarce and contaminated. In this project, I develop population genetic theory and bioinformatic methods that use ancient DNA to refine estimates of when and wher",{"id":948,"funder":7,"programme":8,"title":949,"piName":14,"institution":852,"country":12,"year":13,"amount":168,"abstract":950},"cordis-european-research-council-award-101042990","Spectral Geometry of Higher Categories","The overarching goal of this project is to reveal and systematically study the geometry of important categories in homotopy theory, algebraic geometry, and representation theory. To this end, we will introduce and develop the framework of higher Zariski geometry in which commutative rings are replaced by ring-like categories as the fundamental objects. The resulting theory simultaneously generalizes modern algebraic geometry, derived algebraic geometry as studied by Lurie and Toën--Vezzosi, as w",{"id":952,"funder":7,"programme":8,"title":953,"piName":14,"institution":852,"country":12,"year":13,"amount":14,"abstract":954},"cordis-european-research-council-award-101040037","Formation of planetary building blocks throughout time and space","The major objective of the PLANETOIDS project is to profoundly advance our understanding of planet formation. Numerous discoveries of exoplanets in the last years proved that planet formation is a rule rather than an exception. At the same time, we made unprecedented progress in observations of the birthplaces of planets, the disks surrounding young stars, where dust growth up to pebble-sizes is detected. Despite the significant progress, the planet formation process remains a conundrum as its i",{"id":956,"funder":7,"programme":8,"title":957,"piName":14,"institution":958,"country":35,"year":13,"amount":959,"abstract":960},"cordis-european-research-council-award-101039748","Molecular Design of Electrically Conductive Covalent Organic Frameworks as Efficient Electrodes for Lithium-Ion Batteries","UNIVERSIDAD DE SANTIAGO DE COMPOSTELA","€1,498,619","A major breakthrough in chemistry and materials science has been the development of Lithium-Ion Batteries (LIBs), which show great potential for storing energy from renewable sources and as the power sources for electric cars. However, commercially available LIBs are based on transition metal oxide cathodes, presenting limited energy density and raising relevant environmental concerns. Organic materials have received much attention as alternative electrodes because of their high theoretical capa",{"id":962,"funder":7,"programme":8,"title":963,"piName":14,"institution":852,"country":12,"year":13,"amount":964,"abstract":965},"cordis-european-research-council-award-101039844","Resolving magnetic ORIGINs of the hot solar atmosphere","€1,488,649","The outer atmosphere of the Sun, the corona, is a unique plasma laboratory. It provides key insights into fundamental universal processes such as magnetic reconnection and particle acceleration. Yet, the very existence of the corona in itself is not well understood. It is composed of million Kelvin hot plasma trapped by magnetic fields, and overlies the much cooler 6000 K photosphere, the visible surface of the Sun. All sun-like stars possess such magnetically dominated hotter coronae overlying ",{"id":967,"funder":7,"programme":8,"title":968,"piName":14,"institution":969,"country":88,"year":13,"amount":168,"abstract":970},"cordis-european-research-council-award-101039672","Solving the 'time puzzle' of epigenetic effects on child mental health","ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM","TEMPO aims to solve the newly discovered epigenetic 'time puzzle' of child mental health. Recently it has been observed that common mental health problems in children (e.g. hyperactivity, poor impulse-control) are associated with epigenetic patterns at birth - a mechanism that regulates gene activity in response to genetic and environmental influences. Curiously, however, this association is lost when measuring the same epigenetic patterns later in development. This discovery is highly unexpecte",{"id":972,"funder":7,"programme":8,"title":973,"piName":14,"institution":852,"country":12,"year":13,"amount":974,"abstract":975},"cordis-european-research-council-award-101039433","Increasing Self-Knowledge to Promote Moral Behavior","€1,499,130","The functioning of societies and the quality of interpersonal relationships heavily depend on moral behaviors such as fairness, cooperation, and honesty, whereas immoral behaviors bear tremendous societal costs. A long-standing puzzle facing the social sciences and the humanities is how to promote moral behavior. The prevalent approach is to modify the situation, e.g., through implementing rewards for moral and sanctions for immoral behavior or through nudging. Community and organizational polic",{"id":977,"funder":7,"programme":8,"title":978,"piName":14,"institution":979,"country":12,"year":13,"amount":980,"abstract":981},"cordis-european-research-council-award-101040472","Unravelling the Evolution of Complexes with Ancestral Sequence Reconstruction","PHILIPPS UNIVERSITAET MARBURG","€1,485,013","Almost all proteins perform their functions as part of protein complexes. These assemblies are intricate and often beautiful examples of evolution?s capacity to generate complexity. But are they built by natural selection? My recent work has revealed that they may in fact be produced and maintained across vast time scales by neutral processes, even if they provide no adaptive benefit at all. In this proposal, I will test this radical idea by bringing together ancestral sequence reconstruction an",{"id":983,"funder":7,"programme":8,"title":984,"piName":14,"institution":985,"country":88,"year":13,"amount":986,"abstract":987},"cordis-european-research-council-award-101039545","Towards a circular degrowth economy: Explaining the material valorization regime of city-regions","UNIVERSITEIT VAN AMSTERDAM","€1,431,711","A transition towards a degrowth economy is necessary to tackle the related challenges of resource scarcity and waste accumulation. Degrowth pursues socio-economic wealth while reducing material flows and reusing waste in socially responsible and ecologically regenerative ways. As a concrete approach to realizing these ends, the concept of the circular economy has gathered political momentum. However, this model will have no impact on city-regions' ecological footprint unless it challenges the re",{"id":989,"funder":7,"programme":8,"title":990,"piName":14,"institution":852,"country":12,"year":13,"amount":168,"abstract":991},"cordis-european-research-council-award-101039706","Circuit mechanisms of behavioural variability in Drosophila flight.","While sensory systems report sensory input with high reliability, behavioural responses are inherently variable. How this variability arises and how behavioural decisions are formed, is not well understood in any organism. I will use the fruit fly Drosophila as a model system to study how a specific behaviour is initiated depending on external stimuli and behavioural state. During flight, flies change direction to avoid dangers or search for food with a fast turning response called saccade. This",{"id":993,"funder":7,"programme":8,"title":994,"piName":14,"institution":985,"country":88,"year":13,"amount":995,"abstract":996},"cordis-european-research-council-award-101040876","A New Bayesian Foundation for Psychometric Network Modelling","€1,499,991","Network modelling is quickly gaining ground as a promising way to understand psychological phenomena. The rise of network analysis can be observed throughout the psychological sciences but has been particularly influential in psychopathology. While the network modelling literature has been rapidly expanding, methodological innovations struggle to keep pace. Reviews taking stock of the field invariably zoom in on the methodological challenges that network research faces. The absence of a confirma",{"id":998,"funder":7,"programme":8,"title":999,"piName":14,"institution":1000,"country":161,"year":13,"amount":1001,"abstract":1002},"cordis-european-research-council-award-101039208","Compressed Indexes for Regular Languages with Applications to Computational Pan-genomics","UNIVERSITA CA' FOSCARI  VENEZIA","€1,385,743","Sorting is, arguably, the most powerful algorithmic primitive when it comes to indexing data. At the same time, the regularities exposed by sorting are precisely those enabling data compression. In the last two decades, this fascinating duality has led researchers to the design of compressed full-text indexes: data structures supporting fast pattern matching queries over compressed text. In this project, we revisit the natural generalization of the problem to labeled graphs from a new perspectiv",{"id":1004,"funder":7,"programme":8,"title":1005,"piName":14,"institution":1000,"country":161,"year":13,"amount":1006,"abstract":1007},"cordis-european-research-council-award-101041596","Polyphonic Philosophy: Logic in the Long Twelfth Century (c. 1070-1220) for a New Horizon in the History of Philosophy","€1,498,215","This project aims at an innovative, interdisciplinary approach to Latin logical commentaries from the Long Twelfth-Century (c. 1070-1220). My contention is that this little-explored topic presents us with a unique Polyphonic Philosophy that can open up a new horizon in our understanding of philosophical commentaries, on the one hand, and help to reshape some core ideas in the history of philosophy, on the other - at a time when both are urgently needed. A team of four postdoctoral researchers le",{"id":1009,"funder":7,"programme":8,"title":1010,"piName":14,"institution":1011,"country":161,"year":13,"amount":1012,"abstract":1013},"cordis-european-research-council-award-101039841","Deciphering and Exploiting the chemical features of Silent Lipopolysaccharides: a gift from gut microbiota","UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II","€1,954,308","Gut Microbiota is a key actor for human health, driving many physiological and pathological processes, including immune system development and modulation. How this massive population of microorganisms, most of which are bacteria, establishes commensal, mutualistic or pathogenic interactions with the human host despite the vigilance of the immune system, is still obscure and requires an in-depth study. The story gets more intricate considering that gut is home for a myriad of Gram-negative bacter",{"id":1015,"funder":7,"programme":8,"title":1016,"piName":14,"institution":1017,"country":54,"year":13,"amount":1018,"abstract":1019},"cordis-european-research-council-award-101040051","Enzyme-Mediated Dynamic Combinatorial Chemistry","DANMARKS TEKNISKE UNIVERSITET","€1,499,993","Biomolecular templates define the outcomes of enzymatic reactions in some of the most fundamental of biological processes, such as DNA replication, transcription and translation. In synthetic chemistry, molecular templates have enabled the synthesis of highly complex molecular architectures and interlocked structures. The possibility to use synthetic templates to direct enzymatic reactions and obtain alternative products to those generated in Nature will be investigated in this project.  The ove",{"id":1021,"funder":7,"programme":8,"title":1022,"piName":14,"institution":891,"country":88,"year":13,"amount":14,"abstract":1023},"cordis-european-research-council-award-101040624","Algorithms, Security and Complexity for Quantum Computers","As progress is made in implementing quantum computers, the question is looming: What will we do with them?This proposal is concerned with the theoretical computer science aspects of this question. Part of this question is concerned with quantum algorithms (WP1). We know of several examples of quantum algorithms with large speedups over the best known classical algorithms, such as Shor's poly-time integer factorization algorithm. While this is evidence that quantum computers will be useful once b",{"id":1025,"funder":7,"programme":8,"title":1026,"piName":14,"institution":1027,"country":161,"year":13,"amount":168,"abstract":1028},"cordis-european-research-council-award-101041229","All-liquid phase JANUS BIdimensional materials for functional nano-architectures and assemblies","POLITECNICO DI TORINO","Asymmetry is a key structural feature in natural systems and allows for self-organization and unidirectionality of chemical transformations. JANUS BI aims at developing an innovative protocol for the production of 2D materials bearing different functionalities on the two opposite sides. The challenge is to implement the full process in the liquid phase and thus not resorting to solid phase transfer techniques, which is the current state-of-the-art. With this new method, Janus 2D material colloid",{"id":1030,"funder":7,"programme":8,"title":1031,"piName":14,"institution":1032,"country":323,"year":13,"amount":1033,"abstract":1034},"cordis-european-research-council-award-101041941","Neuropeptidergic modulation of synaptic circuits in fear and anxiety","MEDIZINISCHE UNIVERSITAET WIEN","€1,499,725","Fear and anxiety are Fear and anxiety are essential for survival. Adequate reactions to anticipated and perceived threats strongly depend on the current state, context and previous experience. What are the neurobiological mechanisms that underlie these adaptive behaviors? While synaptic circuits are the backbone to process threat signals and transform them into behavioral responses, increasing evidence suggests that neuropeptides tune these synaptic circuits in a state- and context-dependent man",{"id":1036,"funder":7,"programme":8,"title":1037,"piName":14,"institution":852,"country":12,"year":13,"amount":1038,"abstract":1039},"cordis-european-research-council-award-101041354","The basic principles of polyploidy in plants and animals","€1,495,898","Many eukaryotes have more than two sets of chromosomes due to whole-genome duplication (WGD) and are called polyploids. WGDs explain many cases of speciation bursts and evolutionary inventions. Some evidence suggests an adaptive advantage of polyploids: the origins of many ancient WGDs correspond to the times of extreme climate change, and contemporary polyploids often occupy harsher environments compared to their ancestors. However, most new polyploids are not as lucky and rarely survive. To ex",{"id":1041,"funder":7,"programme":8,"title":1042,"piName":14,"institution":750,"country":239,"year":13,"amount":168,"abstract":1043},"cordis-european-research-council-award-101040800","Deep single-cell phenotyping to identify governing principles and mechanisms of the subcellular organization of bacterial replication","Modern metagenomics has opened our eyes to the immense bacterial diversity that exists both among and within us. Despite this diversity, all bacteria share the basic challenge of organizing the various processes that ensure their faithful replication. All bacterial cells need to metabolize nutrients, generate building blocks, maintain their shape and size, replicate and segregate their chromosomes, synthesize cell walls and membranes, and divide to give rise to daughter cells. At present, we do ",{"id":1045,"funder":7,"programme":8,"title":1046,"piName":14,"institution":1047,"country":1048,"year":13,"amount":1049,"abstract":1050},"cordis-european-research-council-award-101041421","The evolution of host manipulation by bacteriophage.","UNIVERZA V LJUBLJANI","SI","€2,255,511","The idea of parasite manipulation is well known in animal behaviour, with famous examples like the cordyceps ?zombie? fungus of ants. Yet, the most abundant and diverse parasites on earth do not target animals but rather bacteria. They are the bacteriophages, or phages. My hypothesis is that it is in phages that we will find the most important examples of parasite manipulation, examples that will help us both understand and control bacteria, and their impacts. I will focus on the recently-discov",{"id":1052,"funder":7,"programme":8,"title":1053,"piName":14,"institution":1054,"country":239,"year":13,"amount":1055,"abstract":1056},"cordis-european-research-council-award-101043132","Developing technologies to engineer plant genomes at the megabase scale","VIB VZW","€1,496,250","Genomics research combined with revolutionary genome editing tools has created new opportunities to explore fundamental aspects of biology and develop novel (bio)technologies for medicine, agriculture, and industry. The OMEGA project is designed to build on these developments by enabling Megabase-scale engineering of plant genomes. Experimentally-determined lists of essential genes have been crucial for such large-scale projects in other species but are currently unavailable in plants. Therefore",{"id":1058,"funder":7,"programme":8,"title":1059,"piName":14,"institution":1060,"country":88,"year":13,"amount":168,"abstract":1061},"cordis-european-research-council-award-101040703","Organization and function of the axonal Endoplasmic Reticulum","STICHTING RADBOUD UNIVERSITEIT","Brain function relies on neurotransmission at synapses, where local increases in calcium trigger the fusion of synaptic vesicles and release of their neurotransmitters. Decades of research yielded detailed knowledge on synaptic vesicles and the individual proteins that mediate neurotransmission. Conversely, we know surprisingly little about the synaptic contribution of the largest organelle in neurons: the Endoplasmic Reticulum (ER). Aberrant alterations in ER shape are, however, associated with",{"id":1063,"funder":7,"programme":8,"title":1064,"piName":14,"institution":1065,"country":74,"year":13,"amount":1066,"abstract":1067},"cordis-european-research-council-award-101039252","Peers and Possible Partners: Exploring the Origins of Population Long-term Equilibria","ECOLE POLYTECHNIQUE","€1,105,303","Population dynamics are a crucial driver of the prosperity of nations. Nowadays, fertility is too high in less developed countries, impeding their escape from poverty, and too low in more developed countries, threatening their very existence. Another concern is the global rise of childlessness among men, which correlates with mental health issues and social unrest. P3OPLE contributes to addressing these challenges by studying how social and market interactions shape the dynamics and distribution",{"id":1069,"funder":7,"programme":8,"title":1070,"piName":14,"institution":1071,"country":438,"year":13,"amount":1072,"abstract":1073},"cordis-european-research-council-award-101042751","Representative, Reliable and Reproducible in vitro Models of the Human Testes","UNIVERSITY OF LIMERICK","€1,499,980","Western society is on the brink of a fertility crisis, whereby human sperm counts have dropped by 59% over the past four decades and are projected to reach zero by 2045. Treatments for the primary causes of male infertility have no scientific basis, with urologists relying on ineffective empirical medical strategies (guess work). Identifying effective male fertility treatments requires appropriate preclinical models of the sperm-producing testes that can establish a mechanistic basis for treatme",{"id":1075,"funder":7,"programme":8,"title":1076,"piName":14,"institution":1060,"country":88,"year":13,"amount":168,"abstract":1077},"cordis-european-research-council-award-101041938","Chemical Tools for Transcriptome-wide Analysis and Modulation of RNA","RNA is an essential biomolecular polymer that exhibits many cellular functions ranging from catalytic to informational that are crucial for life. Long considered as DNA's unexciting counterpart, RNA has in recent years transcended its dull image, driven by pivotal discoveries of its involvement in cellular signalling pathways. Despite the clear importance of RNA in biology and medicine, many of its properties and functions remain elusive.In the RiboChem program we will develop ground-breaking ch",{"id":1079,"funder":7,"programme":8,"title":1080,"piName":14,"institution":1081,"country":12,"year":13,"amount":1082,"abstract":1083},"cordis-european-research-council-award-101042672","Lithium Niobate Quantum systems","UNIVERSITAET PADERBORN","€2,499,381","Quantum technologies are expected to have a transformative impact by exploiting fundamental quantum mechanical effects for technological applications such as quantum computation, quantum simulation, quantum communication, and quantum sensing. Photons are the only reliable qubit for quantum information transmission, making them an essential resource for quantum technologies. However, quantum photonics will only meet its expectation as a ground breaking technology when integrated in a scalable fas",{"id":1085,"funder":7,"programme":8,"title":1086,"piName":14,"institution":1087,"country":875,"year":13,"amount":1088,"abstract":1089},"cordis-european-research-council-award-101042368","Twisted Ions – A novel tool for quantum science","TAMPEREEN KORKEAKOULUSAATIO SR","€1,499,905","One of the most fundamental principles of quantum physics, the so-called wave-particle dualism of quantum objects, is at the heart of a recently developed research field: twisted matter waves. Similar to their well-established photonic counterparts, coherent beams of massive particles can exhibit a screw-like phase front, which causes an orbital angular momentum. Contrary to photons, however, massive quantum systems can be charged, which results in an additional magnetic moment related to the be",{"id":1091,"funder":7,"programme":8,"title":1092,"piName":14,"institution":1093,"country":12,"year":13,"amount":1094,"abstract":1095},"cordis-european-research-council-award-101040394","Nanocarbon-Ionic Liquid-Interfaces for Catalytic Activation of Nitrogen","FRIEDRICH-SCHILLER-UNIVERSITÄT JENA","€1,498,590","Ammonia is one of the most important chemicals in the world. Electrocatalytic reduction of nitrogen (NRR) at ambient conditions is a sustainable alternative for its production to the established energy consuming Haber-Bosch process, relying on hydrogen from fossil sources. The triple bond in dinitrogen is one of the most stable covalent chemical bonds. Conversely, the dissociation of dinitrogen and its chemical conversion is highly demanding. NRR is a carbon-neutral and decentral process that ca",{"id":1097,"funder":7,"programme":8,"title":1098,"piName":14,"institution":1060,"country":88,"year":13,"amount":1099,"abstract":1100},"cordis-european-research-council-award-101040276","How Hands Help Us Hear","€1,499,988","Human communication in face-to-face conversations is inherently multimodal, combining spoken language with a plethora of multimodal cues including hand gestures. Although most of our understanding of human language comes from unimodal research, the multimodal literature suggests that hand gestures are produced in close synchrony to speech prosody, aligning for instance with stressed syllables in free-stress languages like English. Furthermore, prosody plays a vital role in spoken word recognitio",{"id":1102,"funder":7,"programme":8,"title":1103,"piName":14,"institution":220,"country":221,"year":13,"amount":168,"abstract":1104},"cordis-european-research-council-award-101040128","Visualising neuronal signalling dynamics within intact neuronal circuits:  Deciphering the role of cell-specific MeCP2 dynamics in neuronal function and dysfunction","Epigenetic signalling pathways are required to translate external sensory input to neuronal gene modulation and function, and disruption of epigenetic signals leads to devastating brain pathologies. One prominent example is Rett syndrome (RTT), a postnatal neurodevelopmental disease which results in rapid deterioration of sensory, motor, cognitive, and social functions. RTT is caused by loss of function mutations in a single gene encoding for Methyl-CpG binding protein 2 (MeCP2), an abundant and",{"id":1106,"funder":7,"programme":8,"title":1107,"piName":14,"institution":1108,"country":88,"year":13,"amount":14,"abstract":1109},"cordis-european-research-council-award-101041461","Prime editing to Repair Inherited Metabolic Errors:  in vivo gene correction for human genetic disease","UNIVERSITAIR MEDISCH CENTRUM UTRECHT","Treatment options are insufficient for the majority of genetic metabolic diseases. Methylmalonic acidemia (MMA) is one such severe metabolic disease. With current therapeutic strategies, patients still develop metabolic decompensations, brain damage, kidney failure, and have a lifelong risk to acutely become blind. Repair of the genetic cause of disease would revolutionize outcomes for these patients, especially with increasing detection in neonatal screening programs. This makes it possible to ",{"id":1111,"funder":7,"programme":8,"title":1112,"piName":14,"institution":373,"country":161,"year":13,"amount":1113,"abstract":1114},"cordis-european-research-council-award-101042349","Dots-in-NANOWires by near-field illumination: novel single-photon sources for HYbRid quantum photonic circuits","€1,499,393","Quantum photonic integrated circuits are ideal platforms for quantum computation and communication. A long-standing issue in their realization is the lack of a deterministic quantum light source compatible with silicon. Indeed, planar self-assembled III-V quantum dots (QDs) –which provide high-performance quantum light sources (i. e. single photons)– can hardly be grown on Si, and also lack the positioning control necessary for efficient post-growth III-V-on-Si hybrid integration.Nanowires (NWs)",{"id":1116,"funder":7,"programme":8,"title":1117,"piName":14,"institution":1118,"country":88,"year":13,"amount":168,"abstract":1119},"cordis-european-research-council-award-101041308","Mechanisms of proliferation-independent mutation","KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW","DNA damage contributes to the ageing of tissues and causes mutations that drive cancer. However, the molecular mechanisms underlying many mutational processes are not understood, and neither is how much they contribute to disease. With a powerful new technology, I propose to close these major gaps for common ?clock? mutations of unknown origin.The recent genome sequencing revolution has revealed unexpected diversity in mutational patterns. One pattern in particular is intriguing as it behaves as",200,{"programme":8,"total":1122,"withPiName":1123,"firstYear":1124,"lastYear":1125,"countryCount":1126,"perYear":1127,"topInstitutions":1185,"topCountries":1254},7919,572,2008,2027,52,[1128,1130,1133,1136,1139,1142,1145,1148,1151,1154,1157,1160,1163,1166,1169,1171,1174,1177,1180,1183],{"year":1124,"count":1129},279,{"year":1131,"count":1132},2009,157,{"year":1134,"count":1135},2010,302,{"year":1137,"count":1138},2011,447,{"year":1140,"count":1141},2012,524,{"year":1143,"count":1144},2013,456,{"year":1146,"count":1147},2014,297,{"year":1149,"count":1150},2015,366,{"year":1152,"count":1153},2016,376,{"year":1155,"count":1156},2017,419,{"year":1158,"count":1159},2018,582,{"year":1161,"count":1162},2019,393,{"year":1164,"count":1165},2020,384,{"year":1167,"count":1168},2021,394,{"year":13,"count":1170},514,{"year":1172,"count":1173},2023,512,{"year":1175,"count":1176},2024,473,{"year":1178,"count":1179},2025,482,{"year":1181,"count":1182},2026,556,{"year":1125,"count":1184},6,[1186,1188,1191,1194,1196,1199,1202,1205,1208,1211,1214,1216,1219,1221,1224,1227,1230,1233,1235,1237,1240,1242,1245,1248,1251],{"name":1187,"count":1168},"Centre National de la Recherche Scientifique CNRS",{"name":1189,"count":1190},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",175,{"name":1192,"count":1193},"University of Cambridge",129,{"name":1195,"count":1193},"University of Oxford",{"name":1197,"count":1198},"Hebrew University of Jerusalem",112,{"name":1200,"count":1201},"University College London",110,{"name":1203,"count":1204},"Tel Aviv University",107,{"name":1206,"count":1207},"Weizmann Institute of Science",104,{"name":1209,"count":1210},"Eidgenoessische Technische Hochschule Zuerich",87,{"name":1212,"count":1213},"Kobenhavns Universitet",85,{"name":1215,"count":1213},"Universiteit Gent",{"name":1217,"count":1218},"Universiteit van Amsterdam",84,{"name":47,"count":1220},83,{"name":1222,"count":1223},"Ludwig-Maximilians-Universitaet Muenchen",82,{"name":1225,"count":1226},"Institut National de la Sante Et de la Recherche Medicale",78,{"name":1228,"count":1229},"Universiteit Utrecht",76,{"name":1231,"count":1232},"Imperial College of Science Technology and Medicine",71,{"name":1234,"count":1232},"Katholieke Universiteit Leuven",{"name":1236,"count":1232},"Technische Universiteit Delft",{"name":1238,"count":1239},"Technion - Israel Institute of Technology",70,{"name":1241,"count":1239},"Technische Universitaet Muenchen",{"name":1243,"count":1244},"Universiteit Leiden",69,{"name":1246,"count":1247},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",67,{"name":1249,"count":1250},"The University of Edinburgh",64,{"name":1252,"count":1253},"Helsingin Yliopisto",57,[1255,1257,1260,1262,1264,1265,1267,1269,1271,1273,1275,1277,1279,1281,1282,1284,1286,1288,1290,1292,1294,1296,1299,1302,1304],{"name":12,"count":1256},1346,{"name":1258,"count":1259},"UK",1007,{"name":74,"count":1261},932,{"name":88,"count":1263},772,{"name":161,"count":1173},{"name":35,"count":1266},475,{"name":221,"count":1268},470,{"name":28,"count":1270},389,{"name":239,"count":1272},348,{"name":281,"count":1274},291,{"name":323,"count":1276},269,{"name":54,"count":1278},189,{"name":875,"count":1280},137,{"name":438,"count":1201},{"name":180,"count":1283},108,{"name":61,"count":1285},92,{"name":118,"count":1287},68,{"name":519,"count":1289},60,{"name":398,"count":1291},43,{"name":805,"count":1293},41,{"name":101,"count":1295},36,{"name":1297,"count":1298},"HU",32,{"name":1300,"count":1301},"TR",24,{"name":1048,"count":1303},14,{"name":1305,"count":1306},"EE",10]