[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-erc-synergy-grant-2025":3,"awarded-stats-erc-synergy-grant":359},{"awarded":4,"total":358},[5,16,23,30,37,42,49,56,62,68,74,81,88,94,101,107,113,120,126,131,137,141,147,153,160,165,172,178,183,188,194,201,208,214,220,226,231,237,244,249,255,261,266,272,278,284,290,296,302,308,315,320,324,330,336,341,346,352],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-european-research-council-award-2024-synergy-grant-dynamics","European Research Council","ERC Synergy Grant","On Erdős’ last equation","Florian Luca","Stellenbosch University","ZA",2025,null,"For a positive integer \u003Cinline-formula content-type=\"math\u002Fmathml\"> \u003Cmml:math xmlns:mml=\"http:\u002F\u002Fwww.w3.org\u002F1998\u002FMath\u002FMathML\" alttext=\"n greater-than-or-equal-to 2\"> \u003Cmml:semantics> \u003Cmml:mrow> \u003Cmml:mi>n\u003C\u002Fmml:mi> \u003Cmml:mo> ≥ \u003C\u002Fmml:mo> \u003Cmml:mn>2\u003C\u002Fmml:mn> \u003C\u002Fmml:mrow> \u003Cmml:annotation encoding=\"application\u002Fx-tex\">n\\ge 2\u003C\u002Fmml:annotation> \u003C\u002Fmml:semantics> \u003C\u002Fmml:math> \u003C\u002Finline-formula> , we look at the number of solutions of the Diophantine equation \u003Cdisp-formula content-type=\"math\u002Fmathml\"> \u003Cmml:math xmlns",{"id":17,"funder":7,"programme":8,"title":18,"piName":14,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-european-research-council-award-101167526","Mathematicae Lingua Franca: Bridging the Linguistic Gap Between the Mathematician and the Machine","INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE","FR","€9,981,317","In the recent years, proof assistants have shown their astounding ability to tackle the complete formalisation of large pieces of mathematics, with the celebrated certifications of the Feit-Thompson theorem, of the Kepler conjecture, and more recently, the resolution of Scholze liquid tensor challenge. We believe that the time is ripe to demonstrate that they can tackle mathematics in the flexible and semi-formal way it is created and exchanged by the mathematicians. To that purpose, we aim to d",{"id":24,"funder":7,"programme":8,"title":25,"piName":14,"institution":26,"country":27,"year":13,"amount":28,"abstract":29},"cordis-european-research-council-award-101167313","Natural Auditory SCEnes in Humans and Machines: Establishing the Neural Computations of Everyday Hearing","UNIVERSITEIT MAASTRICHT","NL","€8,622,811","In an office, on a metro, or at home, diverse sounds may be surrounding you: a computer fan, footsteps and indistinct chatter, distant cars, the train slowing down. These sounds shape our environmental awareness, even when visual cues are absent. Despite its ecological relevance, understanding how our brain parses the acoustic scene into semantic objects remains a major scientific challenge. Moreover, individuals with hearing impairments, including those relying on hearing aids or cochlear impla",{"id":31,"funder":7,"programme":8,"title":32,"piName":14,"institution":33,"country":34,"year":13,"amount":35,"abstract":36},"cordis-european-research-council-award-101167171","Atypical Liquid Crystal Elastomers: from Materials Innovation to Scalable processing and Transformative applications","UNIVERSITE DU LUXEMBOURG","LU","€8,477,534","ALCEMIST challenges the conventional engineering mindset where passive static components (beams, wires, joints) are driven by active dynamic ones (motors, dampers, sensors); our innovative materials enable the combined functionality in a single component. This bold ambition is feasible because our research will unlock the full potential of liquid crystal elastomers (LCEs), unique responsive materials that reversibly change shape, colour, adhesive or damping properties, triggered by stimuli like ",{"id":38,"funder":7,"programme":8,"title":39,"piName":14,"institution":40,"country":20,"year":13,"amount":14,"abstract":41},"cordis-european-research-council-award-101166894","Advancing Digital Democratic Innovation","UNIVERSITE TOULOUSE CAPITOLE","The Advancing Digital Democratic Innovation (ADDI) project will pioneer the study of digitally augmented forms of civic participation for preference formation and elicitation. While digital technology has, for some time now, been widely seen as being in direct conflict with the needs of a well-functioning democracy, ADDI will realise the true potential of digital technologies in the democratic space. The project will be led by four well-known researchers with expertise in participatory platform ",{"id":43,"funder":7,"programme":8,"title":44,"piName":14,"institution":45,"country":46,"year":13,"amount":47,"abstract":48},"cordis-european-research-council-award-101167328","Smart Detectors for Darkfield X-ray Imaging","TECHNISCHE UNIVERSITAET MUENCHEN","DE","€10,840,961","The main objective of this project is to improve the early detection and accuracy of lung disease diagnosis by developing a novel detector concept for dark-field X-ray imaging - a novel method with great potential for the assessment of pathological changes in the alveolar microstructure of the lung as recently discovered in initial patient studies. Our research will focus on chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide, responsible for more than 3.2 mi",{"id":50,"funder":7,"programme":8,"title":51,"piName":14,"institution":52,"country":53,"year":13,"amount":54,"abstract":55},"cordis-european-research-council-award-101167218","SKIN-like TWO-Dimensional materials-based elecTRONICS conformable to rough surfaces","UNIVERSITA DI PISA","IT","€9,896,897","The goal of SKIN2DTRONICS is to demonstrate the large scale integration (LSI, transistor count larger than 1000) of soft and thin (skin-like) electronic devices on ultra-flexible substrates, capable of conformally adapting to any rough and curved surface. This vision will be realized by atomically thin two-dimensional materials (2DMs) that possess compelling properties for this application: high electronic performance, environmental stability, low toxicity and cytoxicity, and extreme resilience ",{"id":57,"funder":7,"programme":8,"title":58,"piName":14,"institution":59,"country":27,"year":13,"amount":60,"abstract":61},"cordis-european-research-council-award-101167433","Central roles of mycobacterial type VII secretion systems in intra- and inter-kingdom warfare","STICHTING VU","€10,837,150","Bacteria interact with their environment via specialised secretion systems that deliver proteins outside of the cell. Due to a bias in research efforts, for many years such systems were assumed to be unique to Gram-negative bacteria. A major exception is the type VII secretion system (T7SS), which is widespread in Gram-positive bacteria and actinobacteria, including the important human pathogen Mycobacterium tuberculosis. The T7SS is a complex secretion apparatus that exports folded proteins and",{"id":63,"funder":7,"programme":8,"title":64,"piName":14,"institution":65,"country":46,"year":13,"amount":66,"abstract":67},"cordis-european-research-council-award-101164443","Open 2D Quantum Simulator","EBERHARD KARLS UNIVERSITAET TUEBINGEN","€9,981,952","OPEN-2QS aims to deliver a disruptive change in our capabilities of analog quantum simulation of open 2D many-body systems. For the first time, this will allow us to investigate quantum matter with competing coherent and dissipative processes over extremely long times - a regime that is inaccessible by current technology. This will open a new window for the discovery of emergent dynamical phenomena and states of matter, such as quantum glasses. As any system in Nature eventually couples to an en",{"id":69,"funder":7,"programme":8,"title":70,"piName":14,"institution":71,"country":46,"year":13,"amount":72,"abstract":73},"cordis-european-research-council-award-101166783","Store-And-Forward Energy Grid","RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN","€11,169,627","Electrical power systems are experiencing significant challenges because of the substitution of fossil-based power plants with inverter-based renewable energy sources. This transition pushes power systems to the limits; first severe blackouts have already emerged in developed countries. Although applied for more than 100 years, the rigid coupling of the entire power system infrastructure to a global synchronous 50Hz-frequency is now turning into a liability, making a fundamental paradigm shift i",{"id":75,"funder":7,"programme":8,"title":76,"piName":14,"institution":77,"country":78,"year":13,"amount":79,"abstract":80},"cordis-european-research-council-award-101167362","Targeting the vascular-immune interface to induce anti-tumor immunity","UPPSALA UNIVERSITET","SE","€9,453,750","In this ERC Synergy Grant, we will characterize the vascular-immune interface in melanoma and glioblastoma and explore the perivascular niche as a site for local anti-tumor immune activation.Cancer immunotherapy has made tremendous progress in the last two decades, but a vast majority of cancer patients do not benefit from this progress yet. Refinement of established immunotherapies will undoubtedly increase response rates. However, conceptually brave new therapies must be developed to make addi",{"id":82,"funder":7,"programme":8,"title":83,"piName":14,"institution":84,"country":85,"year":13,"amount":86,"abstract":87},"cordis-european-research-council-award-101167322","DIscovering Flow control in TRANSonic difFUsing  paSsagEs","UNIVERSIDAD POLITECNICA DE MADRID","ES","€9,823,000","The quest for carbon-neutral aviation propels us toward uncharted technological frontiers. In TRANSDIFFUSE, we present an ambitious program to develop an AI-driven model that may revolutionize propulsion technologies. As a synergistic consortium, we unite the numerical modelling prowess of Valero’s team, the high-fidelity computational capabilities of Lehmkuhl’s group, and Paniagua's experimental ingenuity.TRANSDIFFUSE aims to develop new tools related to clean propulsion, specifically an AI-dri",{"id":89,"funder":7,"programme":8,"title":90,"piName":14,"institution":91,"country":78,"year":13,"amount":92,"abstract":93},"cordis-european-research-council-award-101166880","Unravelling Spatio-temporal Auxin Intracellular Redistribution for Morphogenesis (STARMORPH)","SVERIGES LANTBRUKSUNIVERSITET","€10,000,000","STARMORPH is a ground-breaking endeavour with the ambitious goal of understanding plant organ morphogenesis, which will pave the way to engineering plant growth. This is of paramount importance for enhancing agricultural and forestry yields and hence contributing to global food security and environmental sustainability. Plant organ morphogenesis involves differential growth, where various organ parts expand at different rates to create specific structures. A significant challenge lies in underst",{"id":95,"funder":7,"programme":8,"title":96,"piName":14,"institution":97,"country":98,"year":13,"amount":99,"abstract":100},"cordis-european-research-council-award-101166995","The Medieval Book and Networks of Northern Europe c. 1000-1500: Texts, Crafts, Fragments","UNIVERSITETET I BERGEN","NO","€13,069,110","Medieval books were instrumental in shaping European history, communicating rituals, stories and ideas as they were read, copied and shared. To modern scholars they illuminate trade, craft, religious, social and intellectual networks. Less than 10% of the European corpus survives, and in Scandinavia the situation is far worse. However, by historical accident a very high number of Latin fragments – c. 50.000 – from these precious books have been preserved. CODICUM will study and analyse the Nordi",{"id":102,"funder":7,"programme":8,"title":103,"piName":14,"institution":104,"country":78,"year":13,"amount":105,"abstract":106},"cordis-european-research-council-award-101167445","Recycling versus loss in the marine nitrogen cycle: controls, feedbacks, and the impact of expanding low oxygen regions","GOETEBORGS UNIVERSITET","€9,905,916","RECLESS will predict how ongoing ocean deoxygenation impacts microbial nitrogen transformations and thereby the future availability of nitrogen to support oceanic primary production and carbon sequestration. Microbial conversions of bioavailable nitrogen to dinitrogen in oxygen-depleted waters currently account for ~30% of the marine nitrogen loss, despite oxygen-depleted waters making up just 0.1% of the ocean volume. Models predict accelerating expansion of oxygen depletion, which entails incr",{"id":108,"funder":7,"programme":8,"title":109,"piName":14,"institution":110,"country":46,"year":13,"amount":111,"abstract":112},"cordis-european-research-council-award-101166936","Exploring the chemical foundations for rocky exoplanets around Sun-like stars","UNIVERSITAT BAYREUTH","€10,076,633","Billions of rocky worlds likely exist around Sun-like stars in our Galaxy. Yet, attempts to understand these exoplanets lack information on the elements that compose them, the geodynamic processes that drive them, and the atmospheres that cloak them. To meet these cross-disciplinary challenges, three PIs at three institutes have combined forces to break new ground in understanding fully-formed silicate+metal+fluid (i.e. ‘rocky’) exoplanets. By synergizing astronomical data analysis with planetar",{"id":114,"funder":7,"programme":8,"title":115,"piName":14,"institution":116,"country":117,"year":13,"amount":118,"abstract":119},"cordis-european-research-council-award-101167206","The evolution of suprasegmental morphology in West Nilotic","UNIVERSITY OF SURREY","UK","€9,876,341","NILOMORPH sets out to explain how linguistic evolution took a highly unexpected turn in one family of languages spoken in East Africa. They have evolved a morphological system where multiple grammatical categories are expressed simultaneously within a single syllable, through subtle modulations of its phonological properties. For example, in the Dinka language the word tèm, meaning ‘to cut’, can be made to mean ‘she cuts it for someone’ by lengthening the vowel, changing the low tone to high, an",{"id":121,"funder":7,"programme":8,"title":122,"piName":14,"institution":123,"country":46,"year":13,"amount":124,"abstract":125},"cordis-european-research-council-award-101167561","Dynamical and Arithmetical Model Checking","MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV","€7,451,252","Discrete dynamical systems pervade the quantitative sciences, and lie at the heart of central computational challenges in a wide variety of areas, from program analysis and computer-aided verification to neural networks and theoretical biology. Such systems are typically simple to describe, yet give rise to a rich algorithmic and mathematical theory that is replete with easily stated and compelling open problems. One such example is the famous Skolem Problem: does the orbit of a given linear dyn",{"id":127,"funder":7,"programme":8,"title":128,"piName":14,"institution":129,"country":20,"year":13,"amount":14,"abstract":130},"cordis-european-research-council-award-101167367","The geometry of temporal cognitive maps  CHRONOLOGY","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","Experiencing the world and inferring its causal structure rely on the flexible temporal organization of information in the brain, enabling future planning in thoughts and actions. Understanding how the brain maps events in time is essential, yet surprisingly little is known about the neural mechanisms by which the brain represents time and uses it for computations. Based on the observation that complex neural activity accompanies the mental evaluation of time across species, our project aims at ",{"id":132,"funder":7,"programme":8,"title":133,"piName":14,"institution":134,"country":98,"year":13,"amount":135,"abstract":136},"cordis-european-research-council-award-101167183","The system of shape representations in cognition, development and across languages","NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU","€10,459,256","We address a gap in research on the bi-directional effects of language on thought and thought on language, and the developmental pathways that transmit interactions between language and cognition from one generation to the next. The significant empirical advances we propose will result in a unified, cross-disciplinary theory which addresses language diversity through the dynamic interaction of language and cognitive systems across languages and cultures. To this end, we select shape as a core sp",{"id":138,"funder":7,"programme":8,"title":139,"piName":14,"institution":129,"country":20,"year":13,"amount":14,"abstract":140},"cordis-european-research-council-award-101167470","Logic in Reverse Redux. Illegitimate Argumentative Moves in the Arabic, Byzantine, Hebrew and Latin Medieval Traditions","Bad arguments have never been in short supply. The same holds for the scholarly interest they have elicited both in their own right and as a cautionary tale about everything that can go amiss when we argue. This is hardly surprising. Asking what is wrong with flawed arguments is tantamount to investigating the very rules and principles of argumentation – only in reverse. Fallacy Studies have flourished in recent years (especially under the label of «critical thinking»). Without notable exception",{"id":142,"funder":7,"programme":8,"title":143,"piName":14,"institution":144,"country":46,"year":13,"amount":145,"abstract":146},"cordis-european-research-council-award-101167406","Re-engineering symmetry breaking in development and evolution","HUMBOLDT-UNIVERSITAET ZU BERLIN","€10,569,181","Scientists have long sought to understand how complex multicellular organisms generate their final form. Yet despite considerable progress, demonstrating predictive knowledge sufficient to re-engineer development according to design, remains a grand challenge. Addressing this challenge is not only fundamentally important, but also critical to the future of regenerative medicine and agriculture. Development depends on coordinated symmetry breaking events resulting from diverse mechanisms, ranging",{"id":148,"funder":7,"programme":8,"title":149,"piName":14,"institution":150,"country":117,"year":13,"amount":151,"abstract":152},"cordis-european-research-council-award-101167139","Phase-space-inspired numerical methods for high-frequency wave scattering: from semiclassical analysis through numerical analysis to open-source software","UNIVERSITY OF BATH","€8,725,537","Designing fast and reliable algorithms to numerically simulate the behaviour of high-frequency acoustic and electromagnetic waves is a longstanding open problem in computational mathematics. Furthermore, these waves underpin a plethora of communication and imaging technologies; therefore any progress towards solving this problem will have wide impact.The project aims to design, analyse, and implement in open-source software new methods for the numerical solution of high-frequency acoustic and el",{"id":154,"funder":7,"programme":8,"title":155,"piName":14,"institution":156,"country":157,"year":13,"amount":158,"abstract":159},"cordis-european-research-council-award-101166700","A Novel Understanding of Pandemic Disease in Preindustrial Europe (1300-1800): Combining History, Machine Learning and Natural Sciences","UNIWERSYTET MIKOLAJA KOPERNIKA","PL","€9,999,375","Born from years of interdisciplinary collaboration, EUROpest aims to articulate the complex ways in which social-ecological systems  shape epidemics. It builds on resilience and actor-network theories to advance its own eco-bio-social paradigm that embraces a multi-causal understanding of disease transmission and disease impacts on human societies and ecosystems. While striving to develop and validate a general theoretical model, it takes the well-documented and highly diverse world of late medi",{"id":161,"funder":7,"programme":8,"title":162,"piName":14,"institution":123,"country":46,"year":13,"amount":163,"abstract":164},"cordis-european-research-council-award-101167121","Learning in single cells through dynamical internal representations","€11,133,873","Cells continuously sense and interpret the external signals coming from their time-varying environments to generate context-dependent responses. This is true for the entire tree of life, ranging from bacteria and unicellular eukaryotes to neurons forming networks in the developing brain. Identifying the fundamental principles and underlying mechanisms that enable cells to interpret their complex natural surroundings and adequately respond remains one of the fundamental questions in biology. Conc",{"id":166,"funder":7,"programme":8,"title":167,"piName":14,"institution":168,"country":169,"year":13,"amount":170,"abstract":171},"cordis-european-research-council-award-101167089","Nanoscale X-ray tissue imaging: understanding the pathophysiology of hepatitis E infection","UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN","IE","€6,073,099","A driving force behind biomedical innovation lies in disease prevention, diagnosis and treatment. This requires a comprehensive understanding of how pathogens exploit living organisms across molecular, cellular, organismal, and population levels. Treatment of disease often relies upon interventions that restore the normal structure and function of cells. However, it is currently challenging to visualise and quantify detailed cellular changes within whole tissues in response to disease. Soft X-ra",{"id":173,"funder":7,"programme":8,"title":174,"piName":14,"institution":175,"country":27,"year":13,"amount":176,"abstract":177},"cordis-european-research-council-award-101167219","Phonological cognisance and allied linguistic representations: acquisition, bilingualism, change and script","STICHTING RADBOUD UNIVERSITEIT","€10,090,148","PAAL's objective is to investigate the interaction of phonological representations with cognisance, and their relationship to script. We view cognisance as part of the native speaker's core knowledge of their language.This includes generalisations about constraints on phonological representations in terms of features, size and shapes of morphemes, tone and metrical structures. Cognisance is not identical to the phonological representation of particular lexical items",{"id":179,"funder":7,"programme":8,"title":180,"piName":14,"institution":129,"country":20,"year":13,"amount":181,"abstract":182},"cordis-european-research-council-award-101167188","Rise of the Structure-encoded UNC5 interactome in aggressive behaviours of Neuro-developmental tumours","€8,050,793","Paediatric tumours represent a challenge in the landscape of cancer research. Unlike adult cancers, they typically originate from embryonic cells, from which they inherit characteristic embryonic features. This is exemplified by neuroblastoma (NB), the most common solid tumour in young children. NB is a heterogeneous cancer with aggressive metastatic forms, which emerges from neural crest cells. These cells normally undergo a complex migratory process that depends on the functions of cell surfac",{"id":184,"funder":7,"programme":8,"title":185,"piName":14,"institution":123,"country":46,"year":13,"amount":186,"abstract":187},"cordis-european-research-council-award-101167287","Mathematics of Scattering Amplitudes","€9,986,500","MaScAmp proposes a new paradigm for fundamental interactions in physics in the form of a unified mathematical approach to scattering amplitudes. The project brings together a multidisciplinary team with expertise in pure mathematics and theoretical physics who will develop a set of novel and efficient algorithmic methods with applications in mathematics, particle physics and gravity.Discoveries in many areas of fundamental physics depend upon a detailed understanding of the scattering of particl",{"id":189,"funder":7,"programme":8,"title":190,"piName":14,"institution":191,"country":98,"year":13,"amount":192,"abstract":193},"cordis-european-research-council-award-101166850","Molecular Ecology of Medieval European Landscapes","UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET","€13,537,645","MEMELAND will pioneer the creation of Europe's first species-level ecological history, spanning the Roman era to the present day. Our research will unveil the persistent medieval influences in contemporary landscapes and biodiversity. This historical insight will inform proactive land management, conservation, and heritage-informed restoration, crucial for climate change mitigation. Our approach involves sedimentary ancient DNA (sedaDNA), lipid biomarkers, multi-method chronologies, and archaeob",{"id":195,"funder":7,"programme":8,"title":196,"piName":14,"institution":197,"country":198,"year":13,"amount":199,"abstract":200},"cordis-european-research-council-award-101167432","Metamaterial Interfaces for Quantum Electronics","DANMARKS TEKNISKE UNIVERSITET","DK","€13,296,909","The quest to design materials with tailored properties is a driving force for new scientific and technological horizons and is critical for addressing the grand challenges of humanity. Our proposal introduces an innovative concept in condensed matter and materials science: heterostructures built upon the fusion of 2D van der Waals materials and freestanding transition metal oxides (TMOs), forming a new compound metamaterial where the interface itself plays a crucial and active role in the proper",{"id":202,"funder":7,"programme":8,"title":203,"piName":14,"institution":204,"country":205,"year":13,"amount":206,"abstract":207},"cordis-european-research-council-award-101167040","Mapping Occult Sciences Across Islamicate Cultures","UNIVERSITE CATHOLIQUE DE LOUVAIN","BE","€8,954,000","“Mapping Occult Sciences Across Islamicate Cultures” (MOSAIC) is the first major project to investigate Islamic and Eastern Christian occult-scientific sources, spanning from late antiquity to the nineteenth century and from Iberia to India, in a vast continuum of languages (Greek, Syriac, Arabic, Persian, Turkish). It is generally acknowledged that occult sciences—alchemy, astrology, geomancy, lettrism, magic and a wide range of other operative and prognosticative disciplines—are integral to an",{"id":209,"funder":7,"programme":8,"title":210,"piName":14,"institution":211,"country":20,"year":13,"amount":212,"abstract":213},"cordis-european-research-council-award-101167416","Deep learning analysis of imaging and metabolomic data to accelerate antibiotic discovery against antimicrobial resistance","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","€10,968,734","Antimicrobial resistance (AMR) is one of the most pressing global health problems of our times. To counteract AMR, we urgently need new antibiotics, particularly with novel modes of action (MoA). However, while typical antibiotic screening pipelines can identify compounds that impair bacterial growth, they are unable to predict drug targets and MoA so must be followed up by time-consuming target identification steps. By synergizing our expertise in microbiology, genetics, advanced microscopy, me",{"id":215,"funder":7,"programme":8,"title":216,"piName":14,"institution":217,"country":53,"year":13,"amount":218,"abstract":219},"cordis-european-research-council-award-101167101","Reconstructing Embodied Musical knowledge At the Keyboard","UNIVERSITA DEGLI STUDI DI PAVIA","€8,031,361","The fundamental objective of REM@KE is to reconstruct the sound and the function of lost musical instruments and to develop new theoretical, empirical, and practical tools to explore the embodied musical knowledge emerging from the relationships between these instruments and their performers. Among the great variety of objects of the past that inhabit museums, musical instruments are in a category of their own: if kept silent, music cannot be; if played, their materiality is endangered. These in",{"id":221,"funder":7,"programme":8,"title":222,"piName":14,"institution":223,"country":27,"year":13,"amount":224,"abstract":225},"cordis-european-research-council-award-101166915","Light Emitting Silicon Germanium","TECHNISCHE UNIVERSITEIT EINDHOVEN","€13,999,317","Our vision is to revolutionize information and quantum technologies by blending photonic and electronic functionality onto a single chip. This long-standing challenge has remained unattainable because chips, fabricated by mainstream silicon technology, cannot emit light. Computer chips would be much faster and consume far less energy if they would operate with light. In addition, optical functionality will be transformative for quantum computation since silicon technologies are by far the most s",{"id":227,"funder":7,"programme":8,"title":228,"piName":14,"institution":123,"country":46,"year":13,"amount":229,"abstract":230},"cordis-european-research-council-award-101163161","MOLECULAR QUANTUM DYNAMICS IN LOW TEMPERATURE CONDENSED PHASE ASTROCHEMISTRY","€12,085,363","The James Webb Space Telescope (JWST) has ushered in a new era in observational astrochemistry. JWST's ability to obtain infrared spectra of molecular ices condensed on interstellar dust grains in dense, star-forming clouds and in protoplanetary disks is expected to revolutionize the field, since these ices are known to be important sources of complex organic molecules. On a fundamental level, the physico-chemical behavior of these ices obeys the laws of molecular quantum dynamics occurring in l",{"id":232,"funder":7,"programme":8,"title":233,"piName":14,"institution":234,"country":85,"year":13,"amount":235,"abstract":236},"cordis-european-research-council-award-101167065","Engineering an integrated platform for generation of human blood stem cells from pluripotent sources","FUNDACIO INSTITUT HOSPITAL DEL MAR D INVESTIGACIONS MEDIQUES","€9,919,393","Life-saving blood cell replacement depends on voluntary donors. Availability is a challenge for specific groups, and 25% of patients needing blood stem cell transplants lack a compatible donor. The ideal alternative is clinical-scale production of Haematopoietic Stem Cells (HSC) from laboratory-maintained tissue-compatible sources, to provide an off-the-shelf source of blood cells. HSC are generated in the aorta\u002Fgonad\u002Fmesonephros region of the embryo, expand in the foetal liver, and are maintain",{"id":238,"funder":7,"programme":8,"title":239,"piName":14,"institution":240,"country":241,"year":13,"amount":242,"abstract":243},"cordis-european-research-council-award-101167294","Unraveling the Mysteries of Vibrational Strong Coupling","TEL AVIV UNIVERSITY","IL","€9,967,125","Polaritonic Chemistry is a new and exciting field that has emerged from the fusion of chemistry and cavity quantum electrodynamics. In this innovative realm, and specifically under Vibrational Strong Coupling (VSC), hybridizing molecular vibrations with electromagnetic cavity modes has been shown to modify the rate and yield of reactions, solvent polarity and other molecular properties, in the absence of any illumination. The prospects for VSC as a versatile tool for chemistry and materials scie",{"id":245,"funder":7,"programme":8,"title":246,"piName":14,"institution":247,"country":53,"year":13,"amount":92,"abstract":248},"cordis-european-research-council-award-101167102","CUSTOM-MADE NEURONS FOR CELL THERAPY IN PARKINSON’S AND HUNTINGTON’S DISEASE","UNIVERSITA DEGLI STUDI DI MILANO","The rising incidence of age-associated neurodegenerative diseases, due to increased life expectancy, poses a challenge to the brain's limited regenerative capabilities. Stem cell-based therapies offer promise for addressing crucial neuron loss, particularly in Parkinson’s and Huntington’s diseases (PD and HD). Ongoing first-generation stem cell trials, replacing damaged neurons with healthy ones, represent a notable advancement. However, their impact is constrained by a ‘one-cell-fits-all’ gener",{"id":250,"funder":7,"programme":8,"title":251,"piName":14,"institution":252,"country":117,"year":13,"amount":253,"abstract":254},"cordis-european-research-council-award-101167460","Comparative Connectomics: Revealing change and conservation in whole brain circuits across evolution","UNITED KINGDOM RESEARCH AND INNOVATION","€11,927,316","Animals display remarkable diversity in their behaviors, yet very little is known about how nervous systems evolve to generate suchvariation. CircuitEvolution will answer two fundamental questions:1. How does brain wiring change across species as novel behavioral traits evolve?2. What core features of brain circuits are deeply conserved across species?We will use electron microscopy connectomics, the only method that enables unbiased, brain-wide structural analysis of the synapticconnectivity be",{"id":256,"funder":7,"programme":8,"title":257,"piName":14,"institution":258,"country":46,"year":13,"amount":259,"abstract":260},"cordis-european-research-council-award-101166968","The Bacillus subtilis circadian clock:  from molecules to mutualism","LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN","€8,301,946","Circadian clocks are biological timekeepers. They structure processes - from molecular pathways to behavioural attributes - over the 24h day. They are pervasive in eukaryotes yet remain almost completely unknown in bacteria. We propose to address this major knowledge gap by capitalising on our recent breakthrough discovery of a circadian clock in Bacillus subtilis. Our unpublished data reveal that robustness of the B. subtilis circadian clock increases when co-cultured with either the plant Arab",{"id":262,"funder":7,"programme":8,"title":263,"piName":14,"institution":123,"country":46,"year":13,"amount":264,"abstract":265},"cordis-european-research-council-award-101167289","Neuronal implementation of cognitive maps for navigation","€9,992,890","Intelligent behavior is based on internal models of the world that enable mental simulations and strategic planning. A leading model to study such “cognitive maps” are networks of place cells and grid cells in the mammalian hippocampal-entorhinal system. These neurons are active at defined locations and collectively represent a physical environment as a low-dimensional topographic map in neural activity space. However, a mechanistic understanding of the underlying computations and their biologic",{"id":267,"funder":7,"programme":8,"title":268,"piName":14,"institution":269,"country":46,"year":13,"amount":270,"abstract":271},"cordis-european-research-council-award-101166910","Geomagnetic Excursions and Reversals: Establishing their Atmospheric and Climatic Effects","GFZ HELMHOLTZ-ZENTRUM FUR GEOFORSCHUNG","€9,997,634","The intensity of Earth’s magnetic field, which forms an important shield for our habitat, drops dramatically during geomagnetic excursions and reversals (termed GERs). The Laschamps excursion (~41 000 years ago) occurred during profound climatic changes, possibly leading to drastic effects on the biosphere. While impacts of GERs on the atmosphere can be expected, the magnitude, time scales, and even the direction\u002Fsign of effects on our habitat are unknown. The significantly weakened magnetic fie",{"id":273,"funder":7,"programme":8,"title":274,"piName":14,"institution":275,"country":27,"year":13,"amount":276,"abstract":277},"cordis-european-research-council-award-101167181","Metabolism-driven division of minimal cell-like systems","RIJKSUNIVERSITEIT GRONINGEN","€5,000,000","Building a synthetic cell from molecular components is one of the grand scientific and intellectual challenges of the 21st century, and requires interdisciplinary skillsets to design and integrate biochemical modules at different levels of hierarchy. Great progress has been made in the fundamental understanding and reconstitution of key features, such as metabolic reaction networks and replication machinery. However, their successful synergistic integration in minimal cells still lags far behind",{"id":279,"funder":7,"programme":8,"title":280,"piName":14,"institution":281,"country":85,"year":13,"amount":282,"abstract":283},"cordis-european-research-council-award-101166855","Handshake Complexes of Chiral Nanoparticles and Proteins","ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE","€9,272,460","Chirality, or the absence of mirror symmetry, is omnipresent in both biological and abiological forms of matter. Rapid progress has recently been achieved in the synthesis of chiral inorganic nanoparticles (NPs), of great interest because of the giant optical activity observed in individual NPs and their assemblies. Such nanostructures yield chiral features at multiple length scales, resulting in a huge diversity of chiral morphologies. The field is expanding toward connecting chirality across t",{"id":285,"funder":7,"programme":8,"title":286,"piName":14,"institution":287,"country":117,"year":13,"amount":288,"abstract":289},"cordis-european-research-council-award-101167202","Tracing the origin of clonal pathogenesis","THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE","€9,936,185","Epithelial cancers are thought to evolve through a competitive process of mutation and selection in which the serial acquisition of oncogenic mutations confers an increasing fitness advantage, culminating in neoplastic transformation, tumour invasion, and metastasis. This programme often initiates through a phase of field cancerization in which mutant clones expand within the context of physiologically normal-looking tissue. To mitigate the risks associated with field cancerization, protection s",{"id":291,"funder":7,"programme":8,"title":292,"piName":14,"institution":293,"country":117,"year":13,"amount":294,"abstract":295},"cordis-european-research-council-award-101167180","Mutations in healthy tissues: a double-edged sword for tissues homeostasis","THE FRANCIS CRICK INSTITUTE LIMITED","€9,808,142","Healthy tissues become progressively populated of clonally expanded cells that have acquired somatic mutations. Often these mutations modify cancer genes promoting cell plasticity, self-renewal, and growth, all features known to decline with ageing. Despite being pervasive across tissues and persistent throughout life, only rarely mutant cells become pathogenic. Here we hypothesise that somatic mutations enhance tissue integrity by increasing the fitness of stem\u002Fprogenitor cells (SPCs) to counte",{"id":297,"funder":7,"programme":8,"title":298,"piName":14,"institution":299,"country":85,"year":13,"amount":300,"abstract":301},"cordis-european-research-council-award-101167365","Decoding endothelial cell BEhavioral MOSAICism within single vessels","FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS","€10,624,448","Endothelial cells (ECs) form a dynamic monolayer lining the lumen of vessels. While single-cell data have revealed high degrees of heterogeneity amongst ECs at the inter- and intra-organ levels, the prevailing notion has long been that vessels themselves are composed of largely similar ECs.  Instead, data from our labs challenge this view by showing that vessels are built of highly diverse ECs displaying different behavioral properties, a feature we term intravessel EC behavioral mosaicism. Whil",{"id":303,"funder":7,"programme":8,"title":304,"piName":14,"institution":305,"country":46,"year":13,"amount":306,"abstract":307},"cordis-european-research-council-award-101166888","From RNA-peptide coevolution to cellular life at heated air bubbles","TECHNISCHE UNIVERSITAT DORTMUND","€5,972,920","The origin of life on Earth is one of humanity's profound mysteries that lacks scientific answers. We aim to answer this fundamental question by performing pioneering experiments starting from the Darwinian evolution of RNA and peptides to the emergence of cellular life, all in a single environment with only a small selection of starting molecules. We are an interdisciplinary team with diverse backgrounds in chemistry, physics, and biochemistry, and we have a proven track record of strong interd",{"id":309,"funder":7,"programme":8,"title":310,"piName":14,"institution":311,"country":312,"year":13,"amount":313,"abstract":314},"cordis-european-research-council-award-101167045","Concrete matrices for high-cycle-fatigue resistant, eco-efficient infrastructure","VYSOKE UCENI TECHNICKE V BRNE","CZ","€9,993,698","The necessity to meet the rising global demand for mobility and energy supply and, at the same time, the urgency to minimize the carbon footprint, leads to the challenging scientific question of the fatigue resistance of emerging eco-efficient concretes. Since existing knowledge of the traditional Portland-clinker-based binders is largely empirical, it cannot be directly transferred to new binder systems, exhibiting complex chemical and mechanical interactions within the heterogeneous material s",{"id":316,"funder":7,"programme":8,"title":317,"piName":14,"institution":134,"country":98,"year":13,"amount":318,"abstract":319},"cordis-european-research-council-award-101166983","The Hidden Weapon. Blockade in the Era of the Two World Wars","€9,881,766","The main aim of BLOCKADE is to investigate how blockades shaped the course, outcome and aftermath of the world wars. In both wars, belligerents sought to blockade their enemies, cutting them off from vital resources such as food, oil, information and capital to hasten their defeat. Existing research is contradictory and fragmentary, leaving us in the dark as to the scope and the effects of blockades, just as the world is confronted with new blockades.Our hypothesis is that understanding the bloc",{"id":321,"funder":7,"programme":8,"title":322,"piName":14,"institution":123,"country":46,"year":13,"amount":92,"abstract":323},"cordis-european-research-council-award-101167472","Ultrathin Two-Dimensional Polymer Heterostructure Membranes Enabling Unidirectional Ion Transport","Current separation technology is crucial for many aspects of human life and accounts for ~15% of the world’s energy consumption. While the particle flow through separation columns is directional at the atomistic scale, undirected Brownian motion dominates in state-of-the-art membranes. 2D membranes have the potential to overcome this intrinsic deficiency and shift the paradigm of particle transport from disordered Brownian motion to unidirectional flow.We will develop unprecedented 2D polymer he",{"id":325,"funder":7,"programme":8,"title":326,"piName":14,"institution":327,"country":53,"year":13,"amount":328,"abstract":329},"cordis-european-research-council-award-101166930","Unravelling the complexity of the reionization history though simulations and multi-wavelength observations","ISTITUTO NAZIONALE DI ASTROFISICA","€9,765,000","The epoch of Reionization marks the last major transition of the Universe: approximately 400.000 year after the Big bang, the neutral intergalactic medium, mainly composed of hydrogen atoms, started to be ionized by high-energy radiation from the first cosmic sources, stars, galaxies. The onset, timeline and topology of the Reionization process are all tightly linked to the nature of  the sources of ionizing radiation: by identifying and studying them we can gain fundamental insights into what s",{"id":331,"funder":7,"programme":8,"title":332,"piName":14,"institution":333,"country":46,"year":13,"amount":334,"abstract":335},"cordis-european-research-council-award-101167211","A Global Network for the Search for High Frequency Gravitational Waves","RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN","€9,875,391","The overarching goal of the GravNet project is to develop, test and deploy a novel experimental platform that could enable the first detection of gravitational waves (GWs) in the frequency range of MHz to GHz, thereby providing a new and unique window into astrophysical processes that have so far eluded observation. The first detection of gravitational waves by LIGO in 2015 ushered in a new era of fundamental physics. Since then, a network of ground-based GW interferometers has probed the freque",{"id":337,"funder":7,"programme":8,"title":338,"piName":14,"institution":123,"country":46,"year":13,"amount":339,"abstract":340},"cordis-european-research-council-award-101167314","Making Sense of the Unexpected in the Gravitational-Wave Sky","€11,982,258","General Relativity (GR) is more than a century old, but is still our best macroscopic description of gravity. Key GR predictions are black holes (BHs) and gravitational waves (GWs), whose spectacular confirmation led to two recent physics Nobel Prizes. The future of GW astronomy, however, is even brighter, since detectors will observe BHs at cosmic dawn and probe their enigmatic event horizon, where GR clashes with quantum mechanics in the information loss paradox. These experiments will measure",{"id":342,"funder":7,"programme":8,"title":343,"piName":14,"institution":123,"country":46,"year":13,"amount":344,"abstract":345},"cordis-european-research-council-award-101166905","The first comprehensive Atlas of the Milky Way","€9,957,560","The Milky Way is the cosmic environment in which the solar system, the Earth, and life as we know it came into being. It is also the veil through which we peer into the extra-galactic universe. Its dust obscures our view of the formation of the cosmos. Its magnetic fields distort the observations of nature's most powerful particle accelerators. Its structure and metabolism determine the great diversity of observed star and planetary systems, including our own. Due to a lack of distance informati",{"id":347,"funder":7,"programme":8,"title":348,"piName":14,"institution":349,"country":46,"year":13,"amount":350,"abstract":351},"cordis-european-research-council-award-101167207","Mechanical characterization of soft tissue in vivo by microstructural imaging and physics-informed neural networks: bridging the gap between biomechanics and clinical practice","HELMHOLTZ-ZENTRUM HEREON GMBH","€9,991,449","Computational biomechanics is a fast-growing area of science. However, many of its fruits have not yet been translated into clinical practice. The main barrier to the translation of computational biomechanics into clinics is the lack of information about patient-specific mechanical properties of biological tissues. There are some methods for partially assessing these properties, but they have substantial limitations. A major cause of these limitations is the operating principle of current approa",{"id":353,"funder":7,"programme":8,"title":354,"piName":14,"institution":355,"country":46,"year":13,"amount":356,"abstract":357},"cordis-european-research-council-award-101167540","Active Hybrid Photonic Integrated Circuits for Ultra-Efficient Electro-Optic Conversion and Signal Processing","KARLSRUHER INSTITUT FUER TECHNOLOGIE","€13,999,999","Information and communication technology (ICT) crucially relies on the combination of two highly complementary fields: Microelectronics, which excels in processing and storing information using CMOS circuits and photonics, which is key to fast and efficient transmission of information over large distances. Electrical-to-optical conversion in photonic integrated circuits is what links both fields. While efficient conversion from optical signals to electrical signals is straightforward even at a s",58,{"programme":8,"total":360,"withPiName":361,"firstYear":362,"lastYear":363,"countryCount":364,"perYear":365,"topInstitutions":396,"topCountries":453},335,21,2013,2026,28,[366,368,370,373,375,378,381,384,387,390,393,394],{"year":362,"count":367},11,{"year":369,"count":367},2014,{"year":371,"count":372},2015,2,{"year":374,"count":372},2018,{"year":376,"count":377},2019,27,{"year":379,"count":380},2020,37,{"year":382,"count":383},2021,34,{"year":385,"count":386},2022,8,{"year":388,"count":389},2023,33,{"year":391,"count":392},2024,38,{"year":13,"count":358},{"year":363,"count":395},74,[397,400,403,405,408,410,413,415,417,420,422,424,426,428,430,432,435,437,439,441,443,445,447,449,451],{"name":398,"count":399},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",24,{"name":401,"count":402},"Centre National de la Recherche Scientifique CNRS",16,{"name":404,"count":386},"University of Cambridge",{"name":406,"count":407},"Institut National de la Sante Et de la Recherche Medicale",6,{"name":409,"count":407},"Kobenhavns Universitet",{"name":411,"count":412},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",5,{"name":414,"count":412},"Stichting Radboud Universiteit",{"name":416,"count":412},"Universitetet I Oslo",{"name":418,"count":419},"Commissariat A L Energie Atomique Et Aux Energies Alternatives",4,{"name":421,"count":419},"Forschungszentrum Julich Gmbh",{"name":423,"count":419},"Norges Teknisk-Naturvitenskapelige Universitet Ntnu",{"name":425,"count":419},"Technische Universiteit Delft",{"name":427,"count":419},"Tel Aviv University",{"name":429,"count":419},"Universitat Wien",{"name":431,"count":419},"University of Oxford",{"name":433,"count":434},"Aarhus Universitet",3,{"name":436,"count":434},"Ecole Polytechnique Federale de Lausanne",{"name":438,"count":434},"Eidgenoessische Technische Hochschule Zuerich",{"name":440,"count":434},"European Molecular Biology Laboratory",{"name":442,"count":434},"Gfz Helmholtz-Zentrum Fur Geoforschung",{"name":444,"count":434},"Humboldt-Universitaet Zu Berlin",{"name":446,"count":434},"Imperial College of Science Technology and Medicine",{"name":448,"count":434},"King's College London",{"name":450,"count":434},"Rheinische Friedrich-Wilhelms-Universitat Bonn",{"name":452,"count":434},"Universite Catholique de Louvain",[454,456,458,460,461,462,465,466,468,469,472,474,475,477,479,480,482,484,485,487,488,491,493,495,497],{"name":46,"count":455},82,{"name":20,"count":457},43,{"name":117,"count":459},29,{"name":85,"count":377},{"name":27,"count":399},{"name":463,"count":464},"CH",18,{"name":53,"count":464},{"name":198,"count":467},14,{"name":98,"count":467},{"name":470,"count":471},"AT",12,{"name":78,"count":473},10,{"name":241,"count":386},{"name":205,"count":476},7,{"name":478,"count":419},"GB",{"name":312,"count":434},{"name":481,"count":434},"FI",{"name":483,"count":434},"HU",{"name":169,"count":434},{"name":486,"count":372},"HR",{"name":157,"count":372},{"name":489,"count":490},"CN",1,{"name":492,"count":490},"CY",{"name":494,"count":490},"EL",{"name":496,"count":490},"IN",{"name":34,"count":490}]