[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2005":3,"awarded-stats-msca-postdoctoral-fellowship":1106},{"awarded":4,"total":1105},[5,16,23,29,35,41,46,51,57,63,68,74,81,87,92,98,104,109,115,121,126,131,136,141,146,152,158,163,169,175,181,187,193,199,204,210,216,222,227,232,238,244,249,255,262,268,273,279,284,291,297,303,308,313,318,323,329,335,340,346,352,358,363,368,373,378,384,389,392,398,403,408,415,421,426,431,436,441,446,452,457,462,468,473,478,484,490,496,502,507,513,518,524,530,535,542,548,553,559,565,571,577,583,588,594,601,606,612,617,623,628,634,640,646,652,657,663,668,674,679,684,688,693,698,703,708,715,719,725,730,736,742,748,755,760,765,769,774,780,786,791,797,802,808,813,818,824,830,835,841,847,853,859,863,869,875,880,885,891,897,901,906,911,917,923,927,933,938,943,948,952,957,963,969,974,979,984,989,994,999,1004,1009,1014,1018,1024,1029,1034,1040,1045,1050,1055,1061,1066,1071,1076,1080,1085,1090,1095,1100],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-marie-skłodowska-curie-actions-award-9452","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","The morphological evolution of epiphytic mosses",null,"NATURHISTORISKA RIKSMUSEET \u002F SWEDISH MUSEUM OF NATURAL HISTORY","SE",2005,"€165,354","A shift from terrestrial to epiphytic habitats has occurred several times in different evolutionary lineages among mosses. Epiphyte mosses are thus not closely related to each other, but in spite of this they share a number of similar morphological character s. These characters are usually considered as adaptations to epiphytic habitat conditions.Although the correlation between certain morphological characters and epiphytism is striking, the evolutionary pathways and mechanisms behind them are ",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-marie-skłodowska-curie-actions-award-514590","Education and identity politics in Eastern and Western Europe","INSTITUTE OF EDUCATION, UNIVERSITY OF LONDON","UK","€151,675","Overall ProjectObjectives 1.Research objectives: Individual research project:- To gain understanding in the role of education and particularly that of history and geography in the nation-building politics of one young West-European states (Ireland) and on e new East-European state (Ukraine); Project on education, identity and social cohesion (EISC):- To make a substantial contribution to an international project on education, identity and social cohesion, which is headed by Andy Green, prof, of ",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":26,"country":27,"year":13,"amount":10,"abstract":28},"cordis-marie-skłodowska-curie-actions-award-24030","Analyzing the behaviour of ant colony optimization algorithms","UNIVERSITAT POLITèCNICA DE CATALUNYA","ES","Research on a new technique for optimization is initially focused on proof-of-concept applications. It is only after experimental work has shown the practical interest of the method that researchers try to deepen their understanding of the method's functio ning not only through more and more sophisticated experiments but also by means of an effort to build a theory. Tackling questions such as ``how and why the method works'' is important, because finding an answer may help in improving its appli",{"id":30,"funder":7,"programme":8,"title":31,"piName":10,"institution":32,"country":33,"year":13,"amount":10,"abstract":34},"cordis-marie-skłodowska-curie-actions-award-24748","On biharmonic evolution equations","UNIVERSITY OF ULM","DE","In this project we want to consider biharmonic evolution equations on domains with Dirichlet boundary conditions. This evolution problem gives a model for the continuum theory of some special kinds of liquid crystals. The big difference between this biharmonic evolution problem and the corresponding second order problem is that in the higher order case the maximum principle does not hold. A solution of the biharmonic evolution equations in the whole space with a non-negative initial condition ma",{"id":36,"funder":7,"programme":8,"title":37,"piName":10,"institution":38,"country":20,"year":13,"amount":39,"abstract":40},"cordis-marie-skłodowska-curie-actions-award-11621","A 3D imaging system for real time fetal cardiac analysis.","THE UNIVERSITY OF NOTTINGHAM","€159,613","This research program aims to remove the problems of acquiring a clear and accurate 3D dynamic image of the fetal heart during pregnancy. If successful then this will be a diagnostic research instrument that is a world leader in fetal care. This research p roject is only possible by combining the complementary skills of both the fellow (who is a leading industrial expert on real time systems) and the international expertise in medical instrumentation of the host institution, The University of No",{"id":42,"funder":7,"programme":8,"title":43,"piName":10,"institution":44,"country":20,"year":13,"amount":10,"abstract":45},"cordis-marie-skłodowska-curie-actions-award-22218","Social Conflict and Household Welfare: Evidence from India","DEPARTMENT OF ECONOMICS, UNIVERSITY OF SUSSEX","Social conflicts across the world, ranging from civil wars to riots, violent protests and industrial disputes, have affected millions of people and have resulted in lost opportunities in terms of economic growth and human development. Conflicts may, however, not only bring disruption, but may also foster new economic activities; thereby making some people worse-off while others may become better off. Remarkably, current economic literature offers little understanding of what triggers social conf",{"id":47,"funder":7,"programme":8,"title":48,"piName":10,"institution":49,"country":33,"year":13,"amount":10,"abstract":50},"cordis-marie-skłodowska-curie-actions-award-21835","Reconstructing and modelling the history of the El Niño Southern Oscillation Phenomenon Throughout the Holocene","MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V., INSTITUT FÜR BIOGEOCHEMIE","Compound-specific hydrogen isotope ratios (dD) of biomarker compounds (e.g. n-alkanes, fatty acids, sterols etc.) have recently emerged as a new tool to track changes in the water cycle over the geological past. The proposed project will apply this new palaeoclimate proxy for the first time to reconstruct the dominant mode of global climate variability on multi-year timescales, the El Nino Southern Oscillation phenomenon (ENSO) throughout the Holocene. To achieve this objective lake sediment cor",{"id":52,"funder":7,"programme":8,"title":53,"piName":10,"institution":54,"country":55,"year":13,"amount":10,"abstract":56},"cordis-marie-skłodowska-curie-actions-award-21618","Laboratory Investigation of the unrest mechanisms at the Campi Fleigri Caldera: a tool for Mitigating Volcanic hazard","ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA","IT","The Campi Flegrei caldera is unique among resurgent calderas: it has exhibited the most intense episodes of caldera uplift in recent decades, which caused serious threat to the densely inhabited Napolitan area, in Southern Italy. To be in a position to properly calibrate physical models of the caldera, predict and if possible forecast mechanical negative feedbacks, which could lead to catatrosphic eruptions, it appears critical to study the physical and mechanical properties of the host rock, th",{"id":58,"funder":7,"programme":8,"title":59,"piName":10,"institution":60,"country":61,"year":13,"amount":10,"abstract":62},"cordis-marie-skłodowska-curie-actions-award-24275","Identification of interneurons involved in generating locomotor activity","UNIVERSITY OF COPENHAGEN; FACULTY OF HEALTH SCIENCES","DK","The mammalian spinal cord contains neuronal circuits that can generate rhythmic flexion and extension movements - the spinal central pattern generator (CPG) for locomotion. Although the CPG determines the basic pattern of muscular activity, sensory feedback is necessary for adjusting motoneuron recruitment and for determining the timing of switching between the stance and swing phases. Stimulation of afferents transmitting information on length and contraction force of extensor muscles is able t",{"id":64,"funder":7,"programme":8,"title":65,"piName":10,"institution":66,"country":33,"year":13,"amount":10,"abstract":67},"cordis-marie-skłodowska-curie-actions-award-25126","The analysis of paired fin development in the zebrafish","EUROPEAN MOLECULAR BIOLOGY LABORATORY HEIDELBERG","The vertebrate limb constitutes a classic model for the study of developmental processes. Since it comprises a non-vital part of the embryo body, the limb bud can be readily manipulated without affecting survival. In addition, many molecular events that occur during limb development are also present in other embryonic regions; in this way, knowledge acquired from the analysis of limb formation can be used to interpret developmental processes elsewhere. The vertebrate limb originates as a small b",{"id":69,"funder":7,"programme":8,"title":70,"piName":10,"institution":71,"country":55,"year":13,"amount":72,"abstract":73},"cordis-marie-skłodowska-curie-actions-award-8682","Low-dimensional quantum topology","UNIVERSITÃ'  DI PISA","€94,360","The research topic of the proposal is Quantum Topology. This mathematical theory (which involves topology, algebra, and mathematical physics) was born in the 1990's and was inspired by the works of Jones, Witten, Drinfeld, Atiyah, Reshetikhin, Turaev, Kontsevich, and their followers. Structures which originally do not have any relation with topology (such as quantum groups, braided categories) appear of crucial importance in the construction of new topological invariants of knots, of 3-dimension",{"id":75,"funder":7,"programme":8,"title":76,"piName":10,"institution":77,"country":78,"year":13,"amount":79,"abstract":80},"cordis-marie-skłodowska-curie-actions-award-23731","Low dimensional Riemannian and Lorentzian geometry of constant curvature","UNIVERSITE PAUL SABATIER","FR","€151,981","The aim of the present project consists in detecting fundamental structures, which allow a unified understanding of low dimensional Riemannian and Lorentzian manifolds of constant curvature.The point of view is that of Wick rotation-rescaling theory recently outlined by Benedetti and Bonsante. In this framework ends of geometrically finite hyperbolic manifolds support a natural Lorentzian metric for any fixed constant curvature.The first objective is to investigate the relationships between clas",{"id":82,"funder":7,"programme":8,"title":83,"piName":10,"institution":84,"country":78,"year":13,"amount":85,"abstract":86},"cordis-marie-skłodowska-curie-actions-award-25057","Study of high-energy cosmic neutrinos through horizontal air showers with the Pierre Auger Observatory: from detector signals to cosmic-ray phenomenology","INSTITUT NATIONAL DE PHYSIQUE NUCLEAIRE ET DE PHYSIQUE DES PARTICULES (IN2P3) - CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS)","€153,072","High-energy neutrinos of cosmic origin are very important messengers to understand the nature and behaviour of the most energetic sources in the universe. It is believed that such environments produce the enigmatic ultra-high-energy cosmic rays (UHECRs), with energies beyond 10-20 eV. The Pierre Auger Observatory (AUGER), a state-of-the-art hybrid detector under development in Argentina with significant European contribution, allows the detection of both neutrinos and UHECRs with energies above ",{"id":88,"funder":7,"programme":8,"title":89,"piName":10,"institution":90,"country":12,"year":13,"amount":10,"abstract":91},"cordis-marie-skłodowska-curie-actions-award-22222","Mating incompatibility among toxic and non-toxic strains of the dinoflagellate Alexandrium minutum","DEPARTMENT OF LIMNOLOGY LUND UNIVERSITY","In modern society, incidents concerning Harmful Algal Blooms (HABs) are reported with an alarming frequency and there has been an apparent increase in HABs throughout the world over the last decades. Among the multiple poisoning syndromes linked to HABs, Paralytic Shellfish Poisoning (PSP) is the most widespread and significant on a global basis. Dinoflagellates within the genus Alexandrium are responsible for many of the PSP outbreaks in Europe. The geographic expansion of toxin-producing speci",{"id":93,"funder":7,"programme":8,"title":94,"piName":10,"institution":95,"country":33,"year":13,"amount":96,"abstract":97},"cordis-marie-skłodowska-curie-actions-award-11226","High resolution hydrodynamic simulations of star formation and protoplanetary disc evolution","ASTROPHYSIKALISCHES INSTITUT POTSDAM","€149,722","Understanding the formation and evolution of protostellar discs is a key ingredient in star-formation theory. Due to angular momentum conservation, almost all matter falling onto a protostellar object first accretes onto a disc-like structure. The size, ma ss and stability of such a protostellar disc determines the probability of sub- fragmentation into a binary or higher-order multiple system, as well as the properties of the planetary system that may build up in the late phases of disc evoluti",{"id":99,"funder":7,"programme":8,"title":100,"piName":10,"institution":101,"country":78,"year":13,"amount":102,"abstract":103},"cordis-marie-skłodowska-curie-actions-award-7363","Imaging of Localised Corrosion: Local Electrochemical Probes application","UNIVERSITE DE BOURGOGNE","€76,253","Corrosion damages have a major impact on society and economy in terms of injury, environmental damage and financial costs. Developing quantitative models to reliably predict the dynamic performance of the surface of engineering materials is still an open challenge.The scientific and technical issue of this project is to demonstrate that it is possible to combine local electrochemical techniques to go further in the probing and modelling of galvanic and chemical processes involved during pitting ",{"id":105,"funder":7,"programme":8,"title":106,"piName":10,"institution":107,"country":55,"year":13,"amount":10,"abstract":108},"cordis-marie-skłodowska-curie-actions-award-24236","Differences in language structures as a guide to studying cross-cultural differences in cognition: gender and articles","DEPARTMENT OF PSYCHOLOGY OF THE UNIVERSITY OF BOLOGNA","The issue of relation between language and cognition is again, after decades of a relative abandonment, in the centre of scientific interest. Results of recent studies suggest that people from different cultures may differ more in their cognition than previously thought, and that language does indeed provide us with good clues as to where to look for those differences. In most research language is even indicated as a causal force, which, by influencing our cognition from early childhood, brings ",{"id":110,"funder":7,"programme":8,"title":111,"piName":10,"institution":112,"country":27,"year":13,"amount":113,"abstract":114},"cordis-marie-skłodowska-curie-actions-award-6958","Unconditionality and geometrical properties of polynomials on Banach Lattices","UNIVERSITAT DE VALENCIA. ESTUDI GENERAL","€130,778","Despite extensive work in the area of un-conditionality of bases for symmetric tensor products and spaces of polynomials, certain problems remain open, for instance, when do the monomials form an unconditional basic sequence? In a recent paper it has been shown that the polynomials that admit unconditional monomial expansions can be thought of as the multi-linear analogue of the regular linear operators between Banach lattices. This fact opens up a new perspective on the area. We expect that the",{"id":116,"funder":7,"programme":8,"title":117,"piName":10,"institution":118,"country":20,"year":13,"amount":119,"abstract":120},"cordis-marie-skłodowska-curie-actions-award-24122","GTPase regulated signalling pathways: role in the transition from mesenchymal to amoeboid tumor cell invasion","INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL","€168,799","Malignant tumours have acquired the ability to invade surrounding tissue. One component of the invasive phenotype is increased cell motility. Two modes of tumour cell motility have been described: (i) an elongated\u002Fmesenchymal mode that requires extra-cellular proteolysis and (ii) a protease independent\u002Famoeboid\u002Frounded mode. Importantly, these two modes of migration are inter-convertible revealing a novel cellular and molecular adaptation pathway in the switch from a path generating to a path-fi",{"id":122,"funder":7,"programme":8,"title":123,"piName":10,"institution":124,"country":20,"year":13,"amount":10,"abstract":125},"cordis-marie-skłodowska-curie-actions-award-25232","Hheterocycle transformations","CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD","The aims of this research are to develop efficient synthetic methodology for catalytic enantioselective elaboration of heterocycles, and to eventually apply this methodology in strategies for the enantioselective synthesis of selected biologically important structural motifs.",{"id":127,"funder":7,"programme":8,"title":128,"piName":10,"institution":129,"country":78,"year":13,"amount":10,"abstract":130},"cordis-marie-skłodowska-curie-actions-award-022071","The Plant Cytoskeleton in Development","INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE CENTRE DE VERSAILLES-GRIGNON","Plants are unique in many aspects of their biology. In particular, the cytoskeleton is at the centre of many cellular activities essential for cell division and elongation, but also for differentiation and multi-cellular development. It adopts several various spatially independent arrays unique to plant cells. Besides fundamental questions, all aspects of plant development, including its cellular bases, are of interest for agriculture and plant breeding. In this proposal, a combination of approa",{"id":132,"funder":7,"programme":8,"title":133,"piName":10,"institution":134,"country":33,"year":13,"amount":10,"abstract":135},"cordis-marie-skłodowska-curie-actions-award-23983","Scalable autonomic fault tolerance for distributed middleware","UNIVERSITäT ULM","The dependable operation of the global distributed IT infrastructure is of increasing importance for our society. Tolerating failures of components is one important aspect of dependability. For a wider deployment of fault-tolerant systems, (1) the tradeoffs with other aspects of dependability, such as performance and real-time guarantees, must be better understood, and (2) systems must operate in a more autonomic manner, not requiring expert configuration and constant monitoring.This project aim",{"id":137,"funder":7,"programme":8,"title":138,"piName":10,"institution":139,"country":78,"year":13,"amount":10,"abstract":140},"cordis-marie-skłodowska-curie-actions-award-24939","Model theory and geometry of fields with operators","UNIVERSITé PARIS 7- DENIS DIDEROT","We will consider a field K with an operator of one of the following 4 kinds: derivation, automorphism, Hasse derivation and derivation of Frobenius. We are interested in results of two kinds -- geometric and model theoretical (i.e. concerning first-order properties of those structures).First, I explain what kind of geometric results we expect. For an algebraic variety X (or scheme) over K, we enrich the geometry of X by extending the operator to the structure sheaf of X. In the case of a derivat",{"id":142,"funder":7,"programme":8,"title":143,"piName":10,"institution":144,"country":27,"year":13,"amount":10,"abstract":145},"cordis-marie-skłodowska-curie-actions-award-25424","Algebraic Cycles in the Cohomology of Finite Groups","UNIVERSITAT AUTONOMA DE BARCELONA","We propose to continue the study of algebraic cycles in the cohomology rings of finite groups, as initiated in the candidate's PhD thesis. (A cohomology class is called algebraic if it is Poincare dual to the fundamental class of an algebraic manifold mapping into the space under consideration, here the classifying space of a finite group).We have been able in our previous work to do a lot of explicit computations with these. We have been led to formulate a conjecture, which predicts the behavio",{"id":147,"funder":7,"programme":8,"title":148,"piName":10,"institution":149,"country":78,"year":13,"amount":150,"abstract":151},"cordis-marie-skłodowska-curie-actions-award-6853","Branched shadows and invariants of smooth 4-manifolds","UNIVERSITE LOUIS PASTEUR STRASBOURG","€143,433","This application proposes a period of mobility to place a researcher currently developing his own long-term research plan into a leading international research group in the study of torsion and quantum invariants. The goals of the proposal are to complete applicants training on low dimensional topology, and to contribute new scientific results to the area. The scientific aim is to develop the theory of branched shadows of 4-manifolds through two applications: finding 2-cohomology classes satisfy",{"id":153,"funder":7,"programme":8,"title":154,"piName":10,"institution":155,"country":20,"year":13,"amount":156,"abstract":157},"cordis-marie-skłodowska-curie-actions-award-011218","Analysis on fractal-like spaces","IMPERIAL COLLEGE LONDON","€82,131","Since the early 1980's physicists have started to investigate analytical and probabilistic problems on fractals, for instance questions about heat diffusion, Brownian motion and vibration. Fractal structures are convenient models for porous materials and hence are of high interest for natural scientists. These structures appear naturally in medicine, biology, economy, physics and chemistry, but also in pure mathematics.The subject of this research project lies on the borderline edge between stoc",{"id":159,"funder":7,"programme":8,"title":160,"piName":10,"institution":161,"country":27,"year":13,"amount":10,"abstract":162},"cordis-marie-skłodowska-curie-actions-award-22172","Stationary solutions for non-linear random dynamical systems","CENTRE DE RECERCA MATEMÀTICA","The project will primarily address invariant measures of random dynamical systems arising as random perturbations of deterministic infinite-dimensional non-linear systems. Those systems include non-linear parabolic stochastic partial differential equations in bounded, unbounded and periodic domains, systems with memory and related. Our basic tool will be probabilistic representations of solutions for those systems also known as Feynman-Kac type formulae.Our primary goals in studying those system",{"id":164,"funder":7,"programme":8,"title":165,"piName":10,"institution":166,"country":20,"year":13,"amount":167,"abstract":168},"cordis-marie-skłodowska-curie-actions-award-11034","The detailed structure of geomagnetic excursions and their relation to cosmogenic nuclides, and climate variations","THE CHANCELLORS, MASTERS, AND SCHOLARS OF THE UNIVERSITY OF OXFORD","€159,046","The primary scientific objectives of this project are twofold, 1) to improve understanding of the mechanisms which generate the geomagnetic field in the core by careful study of geomagnetic excursions (brief changes in direction and intensity of the geomagnetic field) and, 2) to better understand the correlation between geomagnetic-field intensity, production rate of cosmogenic nuclides, and climate variations.This project will involve a detailed study of two such geomagnetic excursions, the Bla",{"id":170,"funder":7,"programme":8,"title":171,"piName":10,"institution":172,"country":20,"year":13,"amount":173,"abstract":174},"cordis-marie-skłodowska-curie-actions-award-7966","Dynamically defined fractals with overlapping constructions","UNIVERSITY OF WARWICK","€112,112","Since the seventies there has been a growing interest in different branches of the sciences (including physics, chemistry, biology, finance, etc.) about a new phenomenon called fractals''. As a result of this, since the mid-eighties mathematicians have been investigating the structure of fractal sets. The simplest fractals are the so called self similar ones. These are fractals which are unions of their own similar copies (I.e., scaled down versions of the original). These similar copies (so cal",{"id":176,"funder":7,"programme":8,"title":177,"piName":10,"institution":178,"country":179,"year":13,"amount":10,"abstract":180},"cordis-marie-skłodowska-curie-actions-award-21851","Piezoelectric Microactuator via PIM Technology for Micromobile Platform","ARC SEIBERSDORF RESEARCH GMBH","AT","The objective of the project is to adopt the advanced PIM technology to the micro-actuator field and realize the mass production and high precision of piezoelectric micro-actuators for micro-mobile platforms.The research content of the proposal is an inter-discipline in which materials science, mechanical engineering and micro-fabrication are involved. The training of this fellowship will have an indispensable chance to enlarge my research area and of course my ability to facing new challenge si",{"id":182,"funder":7,"programme":8,"title":183,"piName":10,"institution":184,"country":55,"year":13,"amount":185,"abstract":186},"cordis-marie-skłodowska-curie-actions-award-7886","Vector Multiprocessor architecture for multimedia energy-efficient applications","STMICROELECTRONICS S.R.L.","€151,854","The past 10 years have witnessed an explosion of the amount of visual information that must be transmitted and stored efficiently using limited and expensive resources. Advanced video coding that allows orders of magnitude reduction in the required bit-rates is regarded as an enabling technology to move personal communications to a higher level of interactivity. Common features required in personal communication systems are the need for high-quality, low bit-rate video coding implemented in high",{"id":188,"funder":7,"programme":8,"title":189,"piName":10,"institution":190,"country":27,"year":13,"amount":191,"abstract":192},"cordis-marie-skłodowska-curie-actions-award-515397","Physiological, morphological and neurochemical studies of the cortico-spinal pathway in experimental hepatic encephalopathy","INSTITUT DE RECERCA DE L'HOSPITAL UNIVERSITARI VALL D' HEBRON","€139,849","Hepatic Encephalopathy (HE) A is a neuropsychiatric syndrome occurring in both acute and chronic liver failure that includes behavioural, mental and motor disturbances. The more typical motor abnormalities observed are flapping tremor or cortico- spinal signs (exaggerated deep tendon reflexes, Babinski's signs). Those abnormalities significantly diminish the quality of life of the patients.  Clinical studies led by the host of this fellowship have suggested that a low grade brain oedema along th",{"id":194,"funder":7,"programme":8,"title":195,"piName":10,"institution":196,"country":12,"year":13,"amount":197,"abstract":198},"cordis-marie-skłodowska-curie-actions-award-10918","Modelling multimedia fate and exposure of organic chemicals","STOCKHOLMS UNIVERSITET","€156,882","The training program is for Gertje Czub, a very talented young researcher who has developed a unique bioaccumulation model to predict human tissue levels of organic contaminants from their concentrations in the physical environment. The training program consists of two research topics.   The goal of the first topic is to assemble, evaluate, and apply a bioaccumulation model to predict human tissue levels of brominated flame retardants from their levels in the physical environment. In order to ac",{"id":200,"funder":7,"programme":8,"title":201,"piName":10,"institution":202,"country":20,"year":13,"amount":10,"abstract":203},"cordis-marie-skłodowska-curie-actions-award-24984","Monetary and fiscal policy with incomplete markets","LONDON SCHOOL OF ECONOMICS","General equilibrium models become the standard tool for analyzing optimal monetary policy actions. The dominant modelling approach in the study of monetary economies has been to assume that markets are complete.Complete markets are an idealization that agents can trade all commodities on future states of the environment. The implications for authority policies are quite different in models with incomplete markets. We propose to develop a model able to capture these markets imperfections and be a",{"id":205,"funder":7,"programme":8,"title":206,"piName":10,"institution":207,"country":55,"year":13,"amount":208,"abstract":209},"cordis-marie-skłodowska-curie-actions-award-8054","Godel Logics and descriptive properties of the reals","UNIVERSITA DEGLI STUDI DI SIENA","€136,375","This project aims at a thorough mathematical connection of descriptive properties of the reals with semantic properties of Godel logics. If we want to discuss logical descriptions of descriptive, i.e. topological and order theoretic, properties, an adequate logic has to be determined by the order structure of the underlying truth value set, and should not depend on quantitative properties. With other words, validity should be invariant with respect to adequate classes of non-trivial isomorphism.",{"id":211,"funder":7,"programme":8,"title":212,"piName":10,"institution":213,"country":55,"year":13,"amount":214,"abstract":215},"cordis-marie-skłodowska-curie-actions-award-8681","Study of the highest energy cosmic rays with the hybrid technique of the Auger Observatory","UNIVERSITÀ DEGLI STUDI DI ROMA TOR VERGATA, DIPARTIMENTO DI FISICA","€177,628","The Pierre Auger Observatory has been conceived to measure the properties of the highest energy cosmic rays with unprecedented statistics and accuracy. A giant array of surface detectors, covering 3000km2, is viewed in coincidence by a set of 24 fluorescence detector telescopes. The southern site of Malargue, Argentina, is in advanced stage of construction and already collecting data. The concept of hybrid detection of cosmic ray showers is unique of the Auger experiment.The proposal objectives ",{"id":217,"funder":7,"programme":8,"title":218,"piName":10,"institution":219,"country":220,"year":13,"amount":10,"abstract":221},"cordis-marie-skłodowska-curie-actions-award-24885","Organic carbon sequestration and environmental change during the mid-Cretaceous: biogeochemical studies of outcrop pelagic sediments from the Vocontian Basin, SE France","STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE","NL","The mid-Cretaceous 'greenhouse' world, characterised by high atmospheric carbon dioxide levels (3-8 times the pre-industrial values), also experienced widespread deposition of marine sediments anomalously rich in organic carbon. This was due to the presence of oxygen-defficient conditions in the ocean and\u002For high fluxes of organic matter to the sea floor.The term oceanic anoxic events (OAEs) has been coined in the literature to collectively describe such events. The Cenomanian\u002FTuronian boundary ",{"id":223,"funder":7,"programme":8,"title":224,"piName":10,"institution":225,"country":33,"year":13,"amount":10,"abstract":226},"cordis-marie-skłodowska-curie-actions-award-022076","Environmentally conscious lead-free solder bump for ultra-fine pitch flip chip interconnect in electronic packaging","FRAUNHOFER INSTITUTE FOR RELIABILITY AND MICROINTEGRATION","This research project is a fundamental study of lead-free solders for ultra-fine pitch flip chip interconnects in microelectronic packaging, where immersion solder bumping in combination with electroless Ni-P under bump metallization (UBM) is used. Lead-free solders will replace Sn-37Pb in all electronic packaging in near future because of the environmental and healthy concerns. However, it offers a challenge to apply lead-free solders for flip chip interconnect in electronic packaging, due to t",{"id":228,"funder":7,"programme":8,"title":229,"piName":10,"institution":230,"country":220,"year":13,"amount":10,"abstract":231},"cordis-marie-skłodowska-curie-actions-award-23637","Asthma, Endotoxin and Environmental Tobacco Smoke","UNIVERSITEIT UTRECHT","ASETS aims to investigate the relationships between environmental tobacco smoke, endotoxin and asthma. Asthma is an allergic disease of increasing concern within Europe, with considerable impacts on individual health, education and national economies.Our understanding of asthma is improving but there are many areas where scientific investigations are required. Endotoxin is a known agent that can aggravate asthma, but its role in asthma development is complex. Some studies suggest a causal link b",{"id":233,"funder":7,"programme":8,"title":234,"piName":10,"institution":235,"country":20,"year":13,"amount":236,"abstract":237},"cordis-marie-skłodowska-curie-actions-award-10393","Magnetic Fields during the Birth and Death of Stars","THE VICTORIA UNIVERSITY OF MANCHESTER","€162,448","Magnetic fields are believed to play an important role in both the formation of stars and the evolution of stars at the end of their life. However, the exact role of magnetic fields is still under debate. Highly detailed studies of magnetic fields in star-forming regions and in the envelopes of late-type stars have been made possible by recent advances in observational and data reduction techniques in the field of radio interferometry. With Very Long Baseline Interferometry (VLBI) we observe ast",{"id":239,"funder":7,"programme":8,"title":240,"piName":10,"institution":241,"country":33,"year":13,"amount":242,"abstract":243},"cordis-marie-skłodowska-curie-actions-award-23924","Distraction and recovery from distraction: a neurocognitive approach","UNIVERSITAT LEIPZIG","€150,260","Establishing and maintenance of goal-directed behaviour is governed by control processes coordinating the deployment of attention, working memory and response activities. Rare, unpredictable but task-irrelevant events capture our attention, which leads to a performance loss in the task. Normal functioning of the cognitive system is characterized by a balance between maintenance of the goal-directed behaviour and involuntary orientation towards unpredictable task-irrelevant stimulation.The goal o",{"id":245,"funder":7,"programme":8,"title":246,"piName":10,"institution":247,"country":220,"year":13,"amount":10,"abstract":248},"cordis-marie-skłodowska-curie-actions-award-21827","Biogeomorphodynamic modelling of Estuaries for Management purposes","UNIVERSITEIT TWENTE","Estuaries are important for economy and nature. Due to the relatively calm conditions where land meets the water, they are good locations for harbours and are safe havens and feeding grounds for wildlife. These qualities collide in the Western Scheldt. Dredging is required to enable navigation to Antwerp Harbour, but it endangers the stability of the shoals that are important to ecology. The interactions of the bed and the water flow over it shape the estuaries. The bed determines the flow of th",{"id":250,"funder":7,"programme":8,"title":251,"piName":10,"institution":252,"country":55,"year":13,"amount":253,"abstract":254},"cordis-marie-skłodowska-curie-actions-award-513901","Member states and coalition building in a wider and deeper European Union","EUROPEAN UNIVERSITY INSTITUTE","€80,954","The purpose of the proposed research project is to contribute with systematic empirical data to a research field -negotiations and coalition-building in the Council of Ministers of the European Union - which is suffering from too little data to put into existing theoretical models. Current research is strong on formal modelling, but weak on empirical testing. The main empirical puzzle for the project is: Which coalitions are formed, why, and with what consequences? Special attention will be give",{"id":256,"funder":7,"programme":8,"title":257,"piName":10,"institution":258,"country":259,"year":13,"amount":260,"abstract":261},"cordis-marie-skłodowska-curie-actions-award-25499","Transcendental methods in number theory and diophantine problems","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","CH","€176,652","The objectives of the proposal are to increase the mobility of researchers in Europe and provide a training of high quality for the proposer. The scientific project deals with diophantine geometry and transcendental methods in number theory.We will focus on the question of effectivity concerning Siegel's celebrated finiteness theorem on integral points on algebraic curves. The proposed method lies on the famous abc conjecture on diophantine analysis, the Belyi function and etales coverings. In r",{"id":263,"funder":7,"programme":8,"title":264,"piName":10,"institution":265,"country":78,"year":13,"amount":266,"abstract":267},"cordis-marie-skłodowska-curie-actions-award-514943","Tribology of Orthodontic Materials (TOM)","ECOLE CENTRALE DE LYON","€120,081","Orthodontic treatments are increasingly applied to correct teeth alignment and occlusion problems. In France, for instance, recent studies show that nearly 1 million young adolescents have undergone such treatment. The principle of orthodontic treatments is to impose a continuous and slow displacement of teeth by adjusting tension forces between the brackets (stuck to the teeth), and an arch-wire.Recent studies show that friction resistance between the arch-wire and the bracket contacts plays a ",{"id":269,"funder":7,"programme":8,"title":270,"piName":10,"institution":271,"country":33,"year":13,"amount":10,"abstract":272},"cordis-marie-skłodowska-curie-actions-award-21850","OIF to Berkeley USA and Wuppertal Germany","UNIVERSITY OF WUPPERTAL BERGISCHE UNIVERSITAT WUPPERTAL","The representation theory of quantum affine algebra is a fast growing, competitive field of research with many interactions with several branches in mathematics and mathematical physics. My past research in this field leads to new questions and perspectives that I intend to study: first I developed an algebraic approach to q,t-character, independent from the geometric construction of Nakajima. In particular it allows extending the construction of analogues of Kazhdan-Lustig polynomials and of th",{"id":274,"funder":7,"programme":8,"title":275,"piName":10,"institution":276,"country":20,"year":13,"amount":277,"abstract":278},"cordis-marie-skłodowska-curie-actions-award-515386","Understanding smective-water complex","THE NATURAL HISTORY MUSEUM, LONDON","€158,479","Smectite is a clay mineral able to adsorb water. Water is retained between smectite layers; forming a complex with the interlayer cations that balance the charge caused by is omorphous substitution within the layers. This ability to adsorb water is an important control of the physical and chemical properties of soils and surface sediments: stability, subsidence and rising, plant nutrient availability, mobility of chemical species, water availability, etc. Water adsorption on smectite is controll",{"id":280,"funder":7,"programme":8,"title":281,"piName":10,"institution":282,"country":20,"year":13,"amount":10,"abstract":283},"cordis-marie-skłodowska-curie-actions-award-24769","Nonlinear perron-frobenius theory","UNIVERSTITY OF WARWICK","The goal of this research proposal is to solve some fundamental open problems in nonlinear Perron-Frobenius theory. These problems concern order-preserving homogeneous maps on finite dimensional cones and have a distinct dynamical flavour. We shall ask, am ong others, when such maps have an invariant ray in the interior of the cone and investigate the long-term behaviour of orbits of these maps. To analyse these problems we intend to use methods from dynamics of nonexpansive maps and from hyperb",{"id":285,"funder":7,"programme":8,"title":286,"piName":10,"institution":287,"country":288,"year":13,"amount":289,"abstract":290},"cordis-marie-skłodowska-curie-actions-award-515144","Non-commutative geometry of quantum homogeneous spaces","INSTYTUT MATEMATYCZNY, POLSKA AKADEMIA NAUK","PL","€130,875","In global analysis or in algebraic geometry, a geometric space is described by an algebra of functions on this space. Non-commutative geometry extends this approach to geometry also to non-commutative algebras. In this way, A. Connes generalized in particular results from index theory and spin geometry. The aim of this project is to apply the methods of non-commutative geometry to so-called quantum homogeneous spaces. There are several definitions of this notion, but all of them cover a class of",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":294,"country":78,"year":13,"amount":295,"abstract":296},"cordis-marie-skłodowska-curie-actions-award-11269","Precision tests of the Standard Model using beta decay and a novel transparent Paul trap","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE \u002F INSTITUT NATIONAL DE PHYSIQUE NUCLEAIRE ET DE PHYSIQUE DES PARTICULES","€150,237","This proposal is centred on low energy tests of the Standard Model using ion traps. We plan to investigate accurately the beta-neutrino angular correlation coefficient 'a' in nuclear beta decay. According to the Standard Model, 'a' has a well defined value and any deviation from this value will open scenarios for new physics. This deviation can be only observed if 'a' is determined at the per mil level and therefore one needs of very precise measurements. Up to date, the most precise beta-neutri",{"id":298,"funder":7,"programme":8,"title":299,"piName":10,"institution":300,"country":78,"year":13,"amount":301,"abstract":302},"cordis-marie-skłodowska-curie-actions-award-10050","Equivariant infinite dimensional topology","UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6","€151,982","The main objective of this proposal is to continue the study of actions of groups on Q-manifolds and in particular to study the topology of orbit spaces of such actions. The examples of the main interests will be actions of compact groups on hyperspaces of Peano continua induced by actions of those groups on the continua. I plan to extend my results concerning Q-manifold structure of such quotient spaces and of Banach-Mazur compacta.I will also study in details such Q-manifolds structures trying",{"id":304,"funder":7,"programme":8,"title":305,"piName":10,"institution":306,"country":78,"year":13,"amount":10,"abstract":307},"cordis-marie-skłodowska-curie-actions-award-22937","Continuous mappings on compact metrizable spaces","INSTITUT DE MATHéMATIQUES DE JUSSIEU","I propose to study properties of sequences of iterations of a given continuous mapping on a compact metrizable space.From a topological version of the Rosenthal dichotomy, the pointwise closure of the sequence either consists of the pointwise limits of subsequences and then it is called a Rosenthal compact space, or there exists a chaotic subsequence, where chaos is manifested by the fact the pointwise closure of the subsequence is homeomorphic to a copy of the Cech-Stone compactification of the",{"id":309,"funder":7,"programme":8,"title":310,"piName":10,"institution":311,"country":27,"year":13,"amount":10,"abstract":312},"cordis-marie-skłodowska-curie-actions-award-21316","Topological classification of multiple saddle connections","UNIVERSIDAD DE VALLADOLID","The proposal concerns the topological study of dynamical systems given by multiple saddle-connections of hyperbolic saddles of real vector fields in dimension three. As an application, we would like to obtain results on topological finite determinacy for germs in terms of the principal part given by the Newton Polyhedron, producing, by de-singularization a semi-local problem around the exceptional divisor. After achieving the results concerning multiple saddle-connections guided by an exceptiona",{"id":314,"funder":7,"programme":8,"title":315,"piName":10,"institution":316,"country":20,"year":13,"amount":10,"abstract":317},"cordis-marie-skłodowska-curie-actions-award-24806","3D Geodynamics of continental orogens","SCHOOL OF EARTH AND ENVIRONMENT UNIVERSITY OF LEEDS","The goal of the proposed project is to use 3D dynamical modelling to investigate the interplay of convergence and extension in convergent continental orogens. Special emphasis will be on the Alpine-Carpathian-Pannonian geological system of eastern Europe. This region has been intensely investigated through geological and geophysical observations and is thus well suited as a natural laboratory for testing and investigating mechanisms that drive deformation in convergent orogens. The Alpine-Carpat",{"id":319,"funder":7,"programme":8,"title":320,"piName":10,"institution":321,"country":12,"year":13,"amount":10,"abstract":322},"cordis-marie-skłodowska-curie-actions-award-21385","Perturbed evolution of binaries and multiples","LUND UNIVERSITY","I propose a research program with a focus on the evolution of binaries and multiples in dense stellar regions. The study will be applied to the objects formed in a dynamical encounter which are frequently observed in dense stellar systems, and can be studied only using a combination of different techniques, most importantly stellar dynamics, stellar evolution, population synthesis and hydrodynamics. The project will address the following immediate challenging problems: - Young massive clusters: ",{"id":324,"funder":7,"programme":8,"title":325,"piName":10,"institution":326,"country":78,"year":13,"amount":327,"abstract":328},"cordis-marie-skłodowska-curie-actions-award-9949","The response of Evapotranspiration and streamflow to global land cover Transformation: numerical experiments with ORCHIDEE land surface model","UNIVERSITE PIERRE ET MARIE CURIE","€117,814","More than one billion people are forced to drink water from sources contaminated with human waste, devastating floods have resulted in loss of lives, untold material and economic damage, and blistering droughts have resulted in the shortage of available drinking water and rising food insecurity.Our proposed work investigates how this global water crisis is affected by human-caused land cover change. We propose to examine the impact of the present extent of land cover change on the water cycle, i",{"id":330,"funder":7,"programme":8,"title":331,"piName":10,"institution":332,"country":12,"year":13,"amount":333,"abstract":334},"cordis-marie-skłodowska-curie-actions-award-25416","Transcriptional control of neural patterning","KAROLINSKA INSTITUTET","€166,488","Neural",{"id":336,"funder":7,"programme":8,"title":337,"piName":10,"institution":338,"country":12,"year":13,"amount":10,"abstract":339},"cordis-marie-skłodowska-curie-actions-award-23353","New geometries and mathematical tools from and for string theory","UPPSALA UNIVERSITET, INSTITUTIONEN FOR TEORETISK FYSIK","The symbiotic relation between string theory and mathematics has proven to be a gold mine for both fields, providing a guideline for the mathematicians and powerful tools for the physicists.For example, by extending the newly discovered mathematical concept called generalized complex geometry (GCG) to the supersymmetric sigma model, a new understanding of the mathematics of extended supersymmetric sigma models is being achieved.On the other hand, generalized complex manifolds have been shown to ",{"id":341,"funder":7,"programme":8,"title":342,"piName":10,"institution":343,"country":78,"year":13,"amount":344,"abstract":345},"cordis-marie-skłodowska-curie-actions-award-8953","A new approach to the gauge hierarchy problem","UNIVERSITE PARIS 6 PIERRE ET MARIE CURIE","€149,147","While the Standard Model of particle physics is extremely successful in explaining most experimental data in particle physics, it is believe that it is incomplete. First of all, the Higgs boson, predicted by the Standard Model hasn't been discovered yet. If it exists, the Standard Model requires an incredible fine-tuning of one of its parameters. The most well-known, and widely accepted solution to this problem is to embed the Standard Model in a super-symmetric theory. Such theories have been e",{"id":347,"funder":7,"programme":8,"title":348,"piName":10,"institution":349,"country":20,"year":13,"amount":350,"abstract":351},"cordis-marie-skłodowska-curie-actions-award-7323","Integrable Structures in theory of multi-phase flows","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD","€160,294","In recent years, integral structures have been found in a class of hydrodynamics problem leading to pattern formation in a regime far from equilibrium. Growth problems of this type, Laplacian Growth or Hele-Shaw problems, refer to dynamics of a moving front between two distinct phases driven by a harmonic scalar field. These problems have been primarily approached using asymptotic and complex variable methods to address both their stable and the notoriously unstable versions. The relation betwee",{"id":353,"funder":7,"programme":8,"title":354,"piName":10,"institution":355,"country":12,"year":13,"amount":356,"abstract":357},"cordis-marie-skłodowska-curie-actions-award-8254","Political violence in comparative perspective: A system dynamics approach to violent conflicts","UPPSALA UNIVERSITY","€159,117","As a general objective, this project aims to the development of a theoretical framework to analyze and model, from the perspective of System Dynamics and its relation to Peace Studies, situations and conditions of intractability related to both political violence and deep-rooted violent conflicts. It intends to undertake a comparative study using two cases that involve political violence and violent conflict. Such a comparison will address that their internal dynamics of intractability pose to g",{"id":359,"funder":7,"programme":8,"title":360,"piName":10,"institution":361,"country":20,"year":13,"amount":10,"abstract":362},"cordis-marie-skłodowska-curie-actions-award-24738","K-Homology and M-Theory physics","HERIOT-WATT UNIVERSITY","We apply new mathematical tools of certain generalized cohomology theories, namely K-homology and differential cohomology, to study the problem of obtaining realistic four-dimensional backgrounds of string theory suitable for phenomelogical analyses. The consistency conditions implied by the cancellation of global anomalies in string theory are used to establish the conditions under which a given compactification is consistent. Twisted K-theory and K-homology is used to derive an effective actio",{"id":364,"funder":7,"programme":8,"title":365,"piName":10,"institution":366,"country":78,"year":13,"amount":150,"abstract":367},"cordis-marie-skłodowska-curie-actions-award-9541","Algebraic Curves over super-simple fields","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - DELEGATION RHÔNE ALPES - SITE VALLEE DU RHÔNE","The analysis of fields is one of the most active branches of Model Theory, which has found its most spectacular applications in Hrushovski's proofs of the Mordell-Lang and Manin-Mumford conjectures.There are three principal aspects:- ways of interpreting a field,- studying the general properties of fields thus obtained, and- determining the properties of particular theories of fields (with additional algebraic structure like a derivation or an automorphism).All three aspects are closely interrel",{"id":369,"funder":7,"programme":8,"title":370,"piName":10,"institution":371,"country":20,"year":13,"amount":277,"abstract":372},"cordis-marie-skłodowska-curie-actions-award-7547","Transannular Macrocyclisation and the concise total synthesis of Antifungal natural products","IMPERIAL COLLEGE LONDON, DEPARTMENT OF CHEMISTRY","The Barrett group has carried out extensive research on the synthesis of antifungal natural products and the underlying synthetic methodology with recent focus on targets such as nikkomycin B, papuamine, papulacandin, FR-900848, pramanicin, the palmarumyci ns and preussomerin G.This proposal concerns the total synthesis of two bioactive natural products zearalenone and 15G256b. These two macrocyclic compounds are respectively a mycotoxin and an antifungal agent. They possess a highly functionali",{"id":374,"funder":7,"programme":8,"title":375,"piName":10,"institution":376,"country":78,"year":13,"amount":301,"abstract":377},"cordis-marie-skłodowska-curie-actions-award-24717","Determination and measure of transport and mixing at the tropopause","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE","The transport and mixing occurring across the tropopause is a fundamental mechanism determining atmospheric and climate dynamics. Examples of phenomena affected by tropopause exchange include water vapour distribution (and thus weather patterns), greenhou se gases vertical distribution, ozone depletion, and fate of pollutants like airplanes exhausts. Many mathematical tools are available for extracting from wind datasets transport and mixing information, but when applied to the tropopause and co",{"id":379,"funder":7,"programme":8,"title":380,"piName":10,"institution":381,"country":20,"year":13,"amount":382,"abstract":383},"cordis-marie-skłodowska-curie-actions-award-20167","EXPERIMENTAL RECONSTRUCTION AND CHARACTERISATION OF LONG-PERIOD HARMONICS WITH APPLICATION TO VOLCANIC HAZARD PREDICTION: THE LABORATORY VOLCANO.","UNIVERSITY COLLEGE LONDON","€203,590","Europe includes some of the most volcanically active regions on Earth, hosting about 6% of the 600 volcanoes known to have erupted in historical time and, of those, 2-3 are normally in eruption each year. Some 4-5 million people live within sight of an act ive European volcano, and ~10% of the EU population is economically vulnerable. An improved understanding of volcanic mechanisms will directly enhance the quality of life of European citizens, and vulnerable populations worldwide. Seismicity a",{"id":385,"funder":7,"programme":8,"title":386,"piName":10,"institution":387,"country":78,"year":13,"amount":301,"abstract":388},"cordis-marie-skłodowska-curie-actions-award-10275","Loop spaces and the topology of manifolds","UNIVERSITE DES SCIENCES ET TECHNOLOGIE DE LILLE","String Topology is a new field of research which combines several classical techniques of algebraic and geometric topology with the new ideas suggested by quantum field theory and string theory. It was opened to the mathematics community by a pioneering work of Chas and Sullivan in 1999, but it is developing rapidly in a number of directions. We propose an intensive study of this topic addressing the implication of String Topology on the understanding of the topology of the manifolds, with parti",{"id":390,"funder":7,"programme":8,"title":195,"piName":10,"institution":196,"country":12,"year":13,"amount":10,"abstract":391},"cordis-marie-skłodowska-curie-actions-award-24517","The training program is for Dr. Gertje Czub, a very talented young researcher who has developed a unique bioaccumulation model to predict human tissue levels of organic contaminants from their concentrations in the physical environment. The training program consists of two research topics. The goal of the first topic is to assemble, evaluate, and apply a bioaccumulation model to predict human tissue levels of brominated flame retardants from their levels in the physical environment. To achieve t",{"id":393,"funder":7,"programme":8,"title":394,"piName":10,"institution":395,"country":78,"year":13,"amount":396,"abstract":397},"cordis-marie-skłodowska-curie-actions-award-24308","Correction of the atmospheric phase noise in interferometric radio-astronomy by water vapour radiometry","INSTITUT DE RADIOASTRONOMIE MILLIMETRIQUE","€154,206","We will develop a novel system to account for and counteract atmospheric phase noise in millimetre wavelength, radio-astronomical observations, in a quest to boost sensitivity at higher frequencies and higher spatial resolutions. Our innovative approach makes use of specially built, 22 GHz receivers that monitor the atmospheric water vapour content and provide input to a sophisticated model of the atmosphere directly above the telescope. The model will be used to rid the astronomical data of und",{"id":399,"funder":7,"programme":8,"title":400,"piName":10,"institution":401,"country":20,"year":13,"amount":10,"abstract":402},"cordis-marie-skłodowska-curie-actions-award-22443","Epigenetic regulation of vernalization in Arabidopsis thaliana","JOHN INNES CENTRE","Vernalization is the acquisition or acceleration of the ability to flower by chilling treatment. After a prolonged cold treatment, like winter, vernalized plants have the competence to flower, and this competence is remembered during the development of the plant. The molecular basis of this cellular memory is the regulation of the floral repressor FLOWERING LOCUS C (FLC) by the vernalization pathway. FLC mRNA levels decrease during the prolonged cold and this repression is maintained during subs",{"id":404,"funder":7,"programme":8,"title":405,"piName":10,"institution":406,"country":20,"year":13,"amount":10,"abstract":407},"cordis-marie-skłodowska-curie-actions-award-22157","Confocal impedance microscopy of cell interactions with surfaces","QUEEN MARY AND WESTFIELD COLLEGE","A confocal impedance microscope capable of producing two-dimensional electrical images and three-dimensional optical images of materials and cells simultaneously will be developed. The electrical images are produced using two closely related techniques. In formation about the local electrical impedance will be obtained using Scanning Photo-induce Impedance Microscopy; information about local electrical potentials and pH will be obtained from so-called Light-Addressable Potentiometric Sensors. Bo",{"id":409,"funder":7,"programme":8,"title":410,"piName":10,"institution":411,"country":412,"year":13,"amount":413,"abstract":414},"cordis-marie-skłodowska-curie-actions-award-9448","Seismic performance of light-gauge steel framed houses","VTT TECHNICAL RESEARCH CENTRE OF FINLAND","FI","€124,335","The use of light-gauge steel houses is becoming more and more widespread in Europe, even if compared to the market share figures in the United States, Australia or Japan this branch of the industry is still in the initial development phase.Structural solutions are being offered as standard package by companies mainly in Great Britain and the Northern countries, while in other parts of Europe the use of steel framed houses is still at the level of 'experimentation'.This state is also conserved by",{"id":416,"funder":7,"programme":8,"title":417,"piName":10,"institution":418,"country":33,"year":13,"amount":419,"abstract":420},"cordis-marie-skłodowska-curie-actions-award-23403","Dissecting the fluorescence properties of the Enhanced Cyan Fluorescent Protein by computational analysis of its structure and dynamics","UNIVERSITAET BAYREUTH","€149,692","Due to its intrinsic visible fluorescence, the Green Fluorescent Protein (GFP) is used to monitor cellular and biomolecular functions. Its chromophore is formed by cyclization of three aminoacid residues: Ser65, Tyr66 and Gly67. The substitution of Tyr66 b y Trp and few additional mutations lead to the Enhanced Cyan Fluorescent Protein (ECFP), characterized by cyan emission.One unexplained feature is that ECFP has double humped rather than conventional single excitation and emission peaks. NMR a",{"id":422,"funder":7,"programme":8,"title":423,"piName":10,"institution":424,"country":412,"year":13,"amount":10,"abstract":425},"cordis-marie-skłodowska-curie-actions-award-24186","Analysing the impact of pedagogical models within and between collaboration contexts through students' collaboration experiences","UNIVERSITY OF OULU","Collaboration in technology supported environments has become increasingly important for professional contexts. Many companies require that future employees are proficient in such collaboration. Computer-Supported Collaborative Learning (CSCL) is well-suited to teach students the dynamics and skills needed for collaboration in technology supported environments. A large collection of pedagogical models have been shown to stimulate collaboration in electronic environments. A pedagogical model offe",{"id":427,"funder":7,"programme":8,"title":428,"piName":10,"institution":429,"country":220,"year":13,"amount":10,"abstract":430},"cordis-marie-skłodowska-curie-actions-award-21791","Tail asymptotics for random walks and queues","EURANDOM","We propose to investigate three important problems. Namely, we are interested in tail asymptotics for the busy period in the single-server queue, tail asymptotics for the stationary sojourn time in the processor sharing queues and tail asymptotics for the supremum of the random walk with dependent (asymptotically) stationary increments. We plan to study both heavy-tailed and light-tailed cases. In this research we will use theory of large deviations of random walks and we also intend to make a c",{"id":432,"funder":7,"programme":8,"title":433,"piName":10,"institution":434,"country":78,"year":13,"amount":10,"abstract":435},"cordis-marie-skłodowska-curie-actions-award-22988","New approach to plasticity in fatigue of material under multi-axial service loading","LABORATOIRE DE MECANIQUE ET PHYSIQUE DES MATERIAUX (UMR CNRS 6617), ENSMA","The assessment of fatigue life is a very important point in engineering design since most of the elements are subjected to multiaxial dynamic loading, which causes fatigue process.Many multiaxial fatigue failure criteria have been formulated to calculate the fatigue life. The stress-strain relationship (plasticity model) under multiaxial loading is very often required in these criteria. Many of the dynamic loading has the stochastic and multiaxial character.Dealing with such a loading is not eas",{"id":437,"funder":7,"programme":8,"title":438,"piName":10,"institution":439,"country":61,"year":13,"amount":10,"abstract":440},"cordis-marie-skłodowska-curie-actions-award-23556","Impact of increasing CO2 on trophic transfer efficiency in marine food webs","DANISH INSTITUTE FOR FISHERIES RESEARCH","Current models predict a twofold increase in atmospheric CO2 and associated decrease in oceanic pH by about 0.4 units until the end of present century. How this drastic change will affect food webs and trophic transfer in the coastal ocean is unforeseen. We propose to study the effects of these changes on phytoplankton biochemical composition and concurrent effects of potentially altered food quality on secondary producers in the marine systems.",{"id":442,"funder":7,"programme":8,"title":443,"piName":10,"institution":444,"country":27,"year":13,"amount":10,"abstract":445},"cordis-marie-skłodowska-curie-actions-award-22084","Particulate Organic Mater and associated biogenic elements FLUXes in European margins","UNIVERSITAT DE BARCELONA","The main objective is to investigate the transfer of particulate organic mater and nutrients from the surface towards the deeper ocean both in continental margin and open sea settings. The control mechanisms and forcing conditions of this process will be studied as they are the input needed to pin down the capacity of the marine environment of absorbing carbon and withdrawing it from the atmosphere. To address this issue three contrasted sites have been chosen: one oligotrophic-mesotrophic site ",{"id":447,"funder":7,"programme":8,"title":448,"piName":10,"institution":449,"country":20,"year":13,"amount":450,"abstract":451},"cordis-marie-skłodowska-curie-actions-award-10706","Study and Digitisation of Italian Emblem Books in the Stirling Maxwell Collection of the Glasgow University Library","UNIVERSITY OF GLASGOW","€77,822","This project focuses on the study and the digitization of selected 16th-century Italian emblem books now located in Glasgow University Library. Emblems, characterised by the combination of text and image, enjoyed an enormous popularity, and ¿ thanks also t o their figurative elements and the many translations or multilingual editions ¿ had wide circulation across Renaissance Europe in academic, court, religious and bourgeois circles. The emblem corpus constitutes a socio-historical document of E",{"id":453,"funder":7,"programme":8,"title":454,"piName":10,"institution":455,"country":33,"year":13,"amount":10,"abstract":456},"cordis-marie-skłodowska-curie-actions-award-21662","Cosmic strings and dark energy","MAX-PLANCK-INSTITUT FÜR PHYSIK MAX-PLANK-GESELLSCHAFT, MAX-PLANCK-INSTITUT FÜR PHYSIK (WERNER-HEISENBERG-INSTITUT)","In the first part, we propose to generalize the dynamics of Nambu-Goto cosmic strings to include super-conducting currents and higher-order curvature terms. Both super-conducting currents and higher-order curvature terms may drastically influence the gravitation wave signal from cosmic strings that was proposed to be detectable in the case of Nambu-Goto strings by experiments as LIGO, VIRGO and LISA. Dark energy has been suggested as explanation for the observed acceleration of the Universe. The",{"id":458,"funder":7,"programme":8,"title":459,"piName":10,"institution":460,"country":259,"year":13,"amount":10,"abstract":461},"cordis-marie-skłodowska-curie-actions-award-25402","Symplectic Geometry, Cotangent Bundles and Mechanical Systems","ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE","The main objective of this project is to advance significantly the understanding of the symplectic geometry of cotangent bundles endowed with lifted actions, from the point of view of reduction, mechanics and applications.The usual methods of symplectic geometry and symplectic reduction applied to cotangent bundles with Hamiltonian lifted symmetries are not fine enough to treat this important case since the extra bundle structure that makes a cotangent bundle different from other symplectic mani",{"id":463,"funder":7,"programme":8,"title":464,"piName":10,"institution":465,"country":55,"year":13,"amount":466,"abstract":467},"cordis-marie-skłodowska-curie-actions-award-514699","Phylogeography and genetic diversity of the red squirrel, Sciurus vulgaris in Europe, in relation to the range expansion of the American grey squirrel, Sciurus carolinensis","ISTITUTO SUPERIORE PER LA PROTEZIONE E LA RIZERCA AMBIENTALE ( ISPRA)","€143,179","The invasion of the American grey squirrel, Sciurus cardinensis, into the range of the Eurasian red squirrel, Sciurus vulgaris, is threatening the latter species in large parts of Europe, particularly the UK and Northern Italy. Due to the ecological simila rity of the two species, which used to have non-overlapping distribution areas before they were brought together by human influence, their coming together relatively recently on an evolutionary time- scale challenges the limits of coexistence.",{"id":469,"funder":7,"programme":8,"title":470,"piName":10,"institution":471,"country":33,"year":13,"amount":10,"abstract":472},"cordis-marie-skłodowska-curie-actions-award-21687","EU enlargement and South Caucasus Security Building. The need for an integrated strategy","CORE - CENTRE FOR OSCE RESEARCH OF THE INSTITUTE FOR PEACE RESEARCH AND SECURITY POLICY AT THE UNIVERSITY OF HAMBURG (IFSH)","Background and relevance Foreseeable changes in political geography will increase the European Union's exposure to security threats from the South Caucasus. If negotiations due to commence with Turkey in October 2005 reach a successful conclusion, the E U will directly border Armenia, Azerbaijan and Georgia. Already in 2007, after the accession of Bulgaria and Romania, the Union and the South Caucasus will share maritime borders in the Black Sea. EU interests in stabilising the region will grow ",{"id":474,"funder":7,"programme":8,"title":475,"piName":10,"institution":476,"country":61,"year":13,"amount":10,"abstract":477},"cordis-marie-skłodowska-curie-actions-award-25003","Identification, evaluation, and transfer of competences through mergers-and-acquisitions: a knowledge-based perspective","COPENHAGEN BUSINESS SCHOOL","These days the transition to a knowledge economy becomes increasingly observable. The topic is one thematic priority nominated by the EU's 6th Framework program. Contemporary strategic and organisational research describes organisational competences (OC) built on knowledge as the most important factors for gaining and sustaining competitive advantage. A specific Knowledge-based View (KbV) gains in importance.While the impact of OC in competitive environment is well analysed, development processe",{"id":479,"funder":7,"programme":8,"title":480,"piName":10,"institution":481,"country":12,"year":13,"amount":482,"abstract":483},"cordis-marie-skłodowska-curie-actions-award-506004","Enhanced transnational access to abisko scientific research station (ANS)","THE ROYAL SWEDISH ACADEMY OF SCIENCES","€504,000","Nabisco Scientific Research Station is located in one of Europe's last remaining wilderness area. The station is operated year-round in a sub arctic environment; it is well equipped with lab- and field equipment for bio- and geo-scientific investigations. The station can accommodate almost 100 scientists in comfortable rooms and apartments in immediate closeness to study areas. From the station a unique possibility to reach a range of environments exists. Nabisco is easily reached throughout the",{"id":485,"funder":7,"programme":8,"title":486,"piName":10,"institution":487,"country":20,"year":13,"amount":488,"abstract":489},"cordis-marie-skłodowska-curie-actions-award-509292","The politics of financial market regulation: the case of speculative instruments","THE UNIVERSITY OF WARWICK","€125,494","This research proposal deals with the regulation of those financial strategies and vehicles that are generally defined as'instruments of speculation' and looks at the wider societal implications of their activities. The following instruments will beconside red: hedge funds, short selling, single-stock futures and put options. The research will draw upon the work that theFellow has already initiated on hedge funds and will expand its scope by including other vehicles that are the economicequivale",{"id":491,"funder":7,"programme":8,"title":492,"piName":10,"institution":493,"country":494,"year":13,"amount":10,"abstract":495},"cordis-marie-skłodowska-curie-actions-award-21366","How higher education students and faculty utilise individual file storage space, and socially share knowledge and digital information in groups- Implications for e-learning programmes and technologies","EDUCATIONAL MEDIA RESEARCH CENTRE","IE","Current research on learning technologies focuses on the interoperability and standardisation of digital media (or learning objects), and the technical environments that broker these resources. Whilst technical advances are being made towards this end, there are still unanswered questions as to how digital resources are used in practice to support learning. This research proposes an original inquiry into how higher education students and faculty utilise individual file storage space, and sociall",{"id":497,"funder":7,"programme":8,"title":498,"piName":10,"institution":499,"country":20,"year":13,"amount":500,"abstract":501},"cordis-marie-skłodowska-curie-actions-award-10185","GENERATION OF NEW ANTI-RABIES ANTIBODIES FOR POST EXPOSURE PROPHYLAXIS AND PRODUCTION IN PLANTS.","ST. GEORGE'S HOSPITAL MEDICAL SCHOOL","€85,533","Infection by rabies virus causes about 40,000-70,000 deaths per year worldwide. More than 99% of all human deaths occur in Africa, Asia and South America, most commonly involving children aged under 15 years. The recommended therapeuthic procedure for peop le suspected to be infected with this virus includes the immediate administration of both vaccine and rabies specific immunoglobulins (RIG). Prophylaxis in the form of immunoglobulins includes equine anti-rabies immunoglobulins (ERIG) or human",{"id":503,"funder":7,"programme":8,"title":504,"piName":10,"institution":349,"country":20,"year":13,"amount":505,"abstract":506},"cordis-marie-skłodowska-curie-actions-award-25021","Effects of folic acid and its active metabolite 5-methyl-tetrahydrofolic acid on endothelial function, superoxide production and gene expression in human atherosclerosis","€169,367","Endothelial dysfunction is believed to be a major step in atherogenesis. Decreased nitric oxide (NO) bioavailability in human vessels may be the result of both increased oxidative deactivation or decreased production by endothelial nitric oxide synthase (e NOS) in human endothelium.Furthermore, deficiency of tetrahydrobiopterin (BH4), a cofactor for eNOS, leads to eNOS uncoupling, making vascular endothelium a source of superoxide anions. Evidence suggests that folic acid may improve endothelial",{"id":508,"funder":7,"programme":8,"title":509,"piName":10,"institution":510,"country":78,"year":13,"amount":511,"abstract":512},"cordis-marie-skłodowska-curie-actions-award-509400","The role of the Jak tyrosine kinases in the trafficking of the type I interferon receptor","INSTITUT PASTEUR","€74,835","The type l interferon receptor belongs to the class II cytokine receptor family and is expressed on all cell types as a heterodimeric complex that consists of the IFNAR1 and IFNAR2 subunits. Binding of interferon a\u002Fß to its receptor triggers phosphorylation of associated tyrosine kinases of Jak family, Tyk2 and Jak1, and subsequent downstream signalling events. Recent findings have shown that Jak protein tyrosine kinases can control cellular responses to cytokines by influencing receptor localiz",{"id":514,"funder":7,"programme":8,"title":515,"piName":10,"institution":516,"country":259,"year":13,"amount":10,"abstract":517},"cordis-marie-skłodowska-curie-actions-award-24586","Histone modifications and DNA methylation mapping on the entire Human Chromosome 21","FACULTE DE MEDECINE - GENEVA UNIVERSITY","As the sequencing of the human genome nears completion, the challenge that faces the scientific community is to decipher the underlying meaning behind these precisely ordered nucleotides. To exploit the vast amount of information now available from the hum an genome sequencing effort, new strategies focused on understanding gene regulation are being developed. One excellent model for these studies is the Human Chromosome 21 (HC21). This chromosome is the smallest auto-some and for this reason, a",{"id":519,"funder":7,"programme":8,"title":520,"piName":10,"institution":521,"country":20,"year":13,"amount":522,"abstract":523},"cordis-marie-skłodowska-curie-actions-award-22100","Dissection of an evolutionary conserved RNA silencing mechanism in Arabidopsis","THE SAINSBURY LABORATORY","€165,396","RNA-based silencing mechanisms were first recognised from descriptions of co-suppression in transgenic plants and of RNA interference with double stranded RNA in C. elegans. Recently it had become apparent that both experimental silencing mechanisms recapi tulate a natural evolutionary conserved RNA-mediated silencing mechanism. This mechanism is present in all phyla of eukaryotes and can be placed in at least three pathways: 1) cytoplasmic short interfering (si)RNA silencing, 2) micro (mi)RNA s",{"id":525,"funder":7,"programme":8,"title":526,"piName":10,"institution":527,"country":27,"year":13,"amount":528,"abstract":529},"cordis-marie-skłodowska-curie-actions-award-11158","Molecular dissection of transcription factor mediated hematopoietic cell rogramming","CENTER FOR GENOMIC REGULATION","€137,582","Hematopoietic differentiation proceeds through a series of binary decisions where lymphoid and myeloid precursors are specified first, followed by more restricted bi- and monopotent progenitors. Each step involves extinction of the original gene expression program and establishment of a novel gene expression program. This is thought to be accomplished by both antagonistic and synergistic transcription factor interactions that establish cell type specific transcription factor combinations. Recent",{"id":531,"funder":7,"programme":8,"title":532,"piName":10,"institution":533,"country":33,"year":13,"amount":10,"abstract":534},"cordis-marie-skłodowska-curie-actions-award-25579","Mechanism of OPN-mediated mechano-protection in podocytes","UNIVERSITY OF HEIDELBERG, DEPARTMENT OF ANATOMY AND CELL BIOLOGY","Chronic renal failure is characterized by its progressive loss of kidney functions, without therapeutic possibilities. One of the main factors that entail chronic renal failure is glomerular hypertension, which is responsible for the loss or the damage of a highly-specialized epithelial cells of the glomerulus, the podocyte.Podocytes covering the outer aspect of glomerular capillaries and perform interdigitations by their foot processes forming the filter barrier in kidney. The organization of t",{"id":536,"funder":7,"programme":8,"title":537,"piName":10,"institution":538,"country":539,"year":13,"amount":540,"abstract":541},"cordis-marie-skłodowska-curie-actions-award-8467","The role of the Aph-1 proteins in the regulation of the gamma-secretase","FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW","BE","€153,320","The intramembrane proteolysis of the Amyloid Precursor Protein (APP) is the final step in the release of the amyloid peptide, the major constituent of the amyloid plaques in Alzheimer's disease. The protease complex responsible for this proteolytic event consists of Presenilin 1 or 2, Nicastrin, Aph1a or Aph1b, and Pen 2.It is presently not known whether different gamma-secretase complexes exist or whether there is tissue and\u002For substrate specificity of these complexes. It is also unclear whethe",{"id":543,"funder":7,"programme":8,"title":544,"piName":10,"institution":545,"country":20,"year":13,"amount":546,"abstract":547},"cordis-marie-skłodowska-curie-actions-award-9365","Identification and functional characterisation of novel APC binding partners","MEDICAL RESEARCH COUNCIL","€168,231","Adenomatous polyposis coli (APC) is an important tumour suppressor in the human colon epithelium: its loss of function is known to be a primary cause of tumourigenesis, accounting for more than 80% of all heritable and spontaneous colon cancers.The first significant clue for APC function emerged when its association with b-catenin was discovered, providing a molecular link between APC and the Wnt signalling pathway.The Wnt-signalling cascade is strictly conserved from flies to mammals and contro",{"id":549,"funder":7,"programme":8,"title":550,"piName":10,"institution":551,"country":55,"year":13,"amount":10,"abstract":552},"cordis-marie-skłodowska-curie-actions-award-22586","Molecular mechanisms of protein Acetylation Activation: A combined molecular simulation and molecular Biology Approach","INTERNATIONAL SCHOOL OF ADVANCED STUDIES","Nature uses acetylation of lysine residues to modulate the affinity of a variety of nucleic acid binding proteins for their target DNA or RNA. Important examples of such acetylation-based signalling activation processes include the acetylation of Lys residues in histones and the activation of HIV-1 integrase for enhancing the binding affinity to DNA. Surprisingly, no systematic study aimed at understanding the basic molecular mechanisms of acetylation has been performed so far. Here we propose a",{"id":554,"funder":7,"programme":8,"title":555,"piName":10,"institution":556,"country":78,"year":13,"amount":557,"abstract":558},"cordis-marie-skłodowska-curie-actions-award-8659","Anti-CD3 systemic therapy in combination with antigen-specific intervention: A novel approach for treating type 1 diabetes","CENTRE NATIONAL POUR LA RECHERCHE SCIENTIFIQUE","€250,232","Type 1 diabetes (T1D) is thought to be T-cell mediated auto-immune disease, where auto-aggressive CD4+ and CD8+ lymphocytes target and destroy the insulin producing pancreatic b-cells. During the last decade several studies focused on different immune-based therapies to treat or prevent T1D.Numerous data point towards two promising immune interventions:(1) The antigen specific prevention of T1D for example with DNA vaccines, proinsulin, GAD and insulin B chain, which can prevent T1D in more than",{"id":560,"funder":7,"programme":8,"title":561,"piName":10,"institution":562,"country":27,"year":13,"amount":563,"abstract":564},"cordis-marie-skłodowska-curie-actions-award-10091","Mechanisms controlling the developmental response to Wnt signalling in the fruit fly Drosophila melanogaster","UNIVERSIDAD PABLO DE OLAVIDE - CENTRO ANDALUZ DE BIOLOGÍA DEL DESAROLLO","€144,665","The signalling molecule encoded by the wingless (wg) gene (the fruit-fly homologue of the mammalian proto-oncogene Wnt-1) elicits distinct responses in different tissues during the development of the fruit fly Drosophila melanogaster. In particular, wg is required for the proliferation of the hinge cells (which will give rise to the structures joining the wing to the trunk of the fly), and its over-expression leads to the over-proliferation of the hinge cells.In this project we aim at:(1) to def",{"id":566,"funder":7,"programme":8,"title":567,"piName":10,"institution":568,"country":179,"year":13,"amount":569,"abstract":570},"cordis-marie-skłodowska-curie-actions-award-11190","IL-7 dependent commitment of lymphoid progenitors to the B cell pathway","RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY (IMP)","€157,886","During the course of evolution, the immune system has developed to defend us against infections by creating a diverse number of specialized cell types. B-lymphocytes are produced by the differentiation of hematopoietic stem cells (HSC) into gradually more lineage-restricted progenitors. This B cell pathway requires the coordinate action of the early transcription factors PU.1 and Ikaros prior to the activation of the B-cell-specific regulators E2A, EBF and Pax5. In addition, interleukin-7 (IL-7)",{"id":572,"funder":7,"programme":8,"title":573,"piName":10,"institution":574,"country":61,"year":13,"amount":575,"abstract":576},"cordis-marie-skłodowska-curie-actions-award-3086","Development of Long-Term T cell Memory against M. tuberculosis","STATENS SERUM INSTITUT","€259,484","The ability of T cells to respond to a second encounter with antigen is an essential element of memory immunity and indeed a prerequisite of a successful vaccination. Many recent advances have been made in our understanding of the cellular basis of immunological memory (reviewed by Kaech) (1). However, major gaps in our knowledge on the generation and persistence of cell mediated immunological (CMI) memory still exist. In particular, factors that allow vaccines to generate long-lived memory are ",{"id":578,"funder":7,"programme":8,"title":579,"piName":10,"institution":580,"country":78,"year":13,"amount":581,"abstract":582},"cordis-marie-skłodowska-curie-actions-award-22003","genetic control of craniofacial development by hox cofactors Pbx1 and Pbx2","CENTRE EUROPéEN DE RECHERCHE EN BIOLOGIE ET MEDECINE-GROUPEMENT D'INTéRêT ECONOMIQUE","€257,923","One third of all human congenital malformations affects craniofacial development and represents a serious concern for society. Within the developing primordia, unique spatio temporal patterns of gene expression correlate with cellular and tissue fates, id entities and behaviours and therefore, morphogenesis.The goal of this proposal is to finely dissect the genetic control of craniofacial development with particular focus on CNC (cranial neural crest cell) cell specification and craniofacial mor",{"id":584,"funder":7,"programme":8,"title":585,"piName":10,"institution":349,"country":20,"year":13,"amount":586,"abstract":587},"cordis-marie-skłodowska-curie-actions-award-23087","Electrophysiological and behavioural studies of phonological short-term memory in children with autism: A comparison with Specific Language Impairment","€156,778","There are two developmental disorders in which communication skills are a major area of difficulty: autistic disorder, and specific language impairment (SLI). In autistic disorder, communication difficulties encompass both verbal and nonverbal aspects, and are associated with problems in socialisation and behavioural repertoire. SLI is a more selective disorder, in which the child develops along normal lines, except in the area of verbal language, where skills lag behind those of other children ",{"id":589,"funder":7,"programme":8,"title":590,"piName":10,"institution":591,"country":20,"year":13,"amount":592,"abstract":593},"cordis-marie-skłodowska-curie-actions-award-22469","Ab initio molecular dynamics study of redox reactions in solution","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE","€161,994","The aim of this work is density functional based computation of thermodynamic and kinetic coefficients of redox reactions in solution, and relates these observable quantities to the electronic structure of electrochemical systems. Our computational tool is the ab initio molecular dynamics method. This method applies density functional theory (DFT) and molecular dynamics simulation techniques to make molecular model systems move under the influence of adiabatic forces obtained from a continuously",{"id":595,"funder":7,"programme":8,"title":596,"piName":10,"institution":597,"country":598,"year":13,"amount":599,"abstract":600},"cordis-marie-skłodowska-curie-actions-award-6254","Spectral properties of perturbed quantum waveguides","NUCLEAR PHYSICS INSTITUTE, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC","CZ","€96,551","The aim of the presented project is to study spectral properties of perturbed quantum waveguides. We are going to treat the physically important cases of dimensions of two and three. The main effort will focus at investigation of the spectral behaviour under perturbations and calculation of the corresponding asymptotical expansion. This project will allow us to continue a successful collaboration which started two years ago and has allowed us already to combine techniques used in both institutes",{"id":602,"funder":7,"programme":8,"title":603,"piName":10,"institution":604,"country":78,"year":13,"amount":10,"abstract":605},"cordis-marie-skłodowska-curie-actions-award-21822","Characterization of the neurobiological processes underlying the antiparkinsonian effects of nicotine","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","Epidemiological studies indicate that cigarette smoking protects from Parkinson's disease (PD), and a recent unpublished clinical study has shown that progressively increasing doses of nicotine improve the symptoms of PD and allow patients to dramatically reduce their dosages of L-DOPA, the most widely used anti-PD treatment. How nicotine may interact with L-DOPA to enhance functioning in PD, however, remains unknown. In preliminary studies using an animal model of PD, Sokoloff and colleagues ha",{"id":607,"funder":7,"programme":8,"title":608,"piName":10,"institution":609,"country":220,"year":13,"amount":610,"abstract":611},"cordis-marie-skłodowska-curie-actions-award-23788","Metabolomics of salicylate induced plants","LEIDEN UNIVERSITY","€149,276","Salicylate is an important signal compound in plants connected with resistance against viral and fungal infections. Little is known about the metabolic changes involved with the induction of resistance by salicylate. Metabolomics offers a novel tool to study these changes and will be helpful in increasing our understanding of the resistance mechanisms.For this study we will use tobacco plants over-expressing microbial genes involved in the salicylate biosynthesis (patented from the host laborato",{"id":613,"funder":7,"programme":8,"title":614,"piName":10,"institution":615,"country":412,"year":13,"amount":10,"abstract":616},"cordis-marie-skłodowska-curie-actions-award-25288","Role of fgf receptor 1 and 2 in the midbrain development and dopaminergic neuron differentiation","INSTITUTE OF BIOTECHNOLOGY, THE UNIVERSITY OF HELSINKI","Patterning of midbrain and specification of the midbrain dopaminergic neurons is controlled by signalling molecules Sonic hedgehog (Shh) and Fibroblast growth factor 8 (Fgf8). In embryogenesis, Fgf8 can transduce its signal via three Fgf receptors (Fgfr). W e want to find out whether Fgfr 1 and 2 are required for differentiation of the midbrain and the midbrain dopaminergic neurons.Our model is conditional inactivation of Fgr1 and 2 in mice. We will perform spatially and temporally controlled ab",{"id":618,"funder":7,"programme":8,"title":619,"piName":10,"institution":620,"country":259,"year":13,"amount":621,"abstract":622},"cordis-marie-skłodowska-curie-actions-award-11333","Single-spin electron resonance","EIDGENOSISCHE TECHNISCHE HOCHSCHULE ZURICHSWISS FEDERAL INSTITUTE OF TECHNOLOGY ZURICH","€173,832","The goal of this project is the manipulation of spin properties of quantum dots by microwave signals. We will use a high-Q microwave cavity, developed in ETHZ, in order to maximize the magnetic field strength at the location of the quantum dot and keeping the total power of the microwave below the cooling power of the dilution refrigerator. The focus will first be on electron spin resonance, then we will study the possibility to manipulate spin states by GHz pulses in order to prepare well-defin",{"id":624,"funder":7,"programme":8,"title":625,"piName":10,"institution":626,"country":259,"year":13,"amount":10,"abstract":627},"cordis-marie-skłodowska-curie-actions-award-24749","High precision mass measurements of short-lived radionuclides at the Penning trap mass spectrometer ISOLTRAP","EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH","The determination of atomic masses is of importance in various branches of physics. Being unique as a fingerprint, the masses of short-lived nuclides contribute to stringent tests of nuclear structure models, astrophysical models, e.g. for the nucleosynthesis of the elements, and even to tests of the Standard Model with respect to the Weak Interaction. With the Penning-trap mass spectrometer ISOLTRAP at ISOLDE\u002FCERN the masses of exotic nuclides can be measured at a level of less than 0.01 parts ",{"id":629,"funder":7,"programme":8,"title":630,"piName":10,"institution":631,"country":179,"year":13,"amount":632,"abstract":633},"cordis-marie-skłodowska-curie-actions-award-515392","The Role of RANK and RANKL in breast cancer and metastasis generation of new mouse model for breast cancer research","INSTITUTE OF MOLECULAR BIOTECHNOLOGY OF THE AUSTRIAN ACADEMY OF SCIENCES","€148,829","Breast cancer is the second leading cause of cancer death in women after lung cancer. Breast cancers are frequently associated with bone metastasis resulting in severe disease burden pain, and death. Josef Penninger was the first to show that the Receptor-activator of NF-kB(RANK) and its ligand (RANKL) are essential for osteoclast differentiation, activation and survival, as well as for mammary gland development. In addition, expression of RANK was detected in various breast cancer cell lines. S",{"id":635,"funder":7,"programme":8,"title":636,"piName":10,"institution":637,"country":220,"year":13,"amount":638,"abstract":639},"cordis-marie-skłodowska-curie-actions-award-6828","Integration between rail and access-to-rail-station Modes","VRIJE UNIVERSITEIT, FACULTY OF ECONOMICS AND BUSINESS ADMINISTRATION","€149,821","A rail journey is rarely an end in itself; it is almost always part of a journey `chain' that includes a journey to, and later from, the railway station by different modes of transport. The integration of the rail-journey components is essential to achieve a continuous travel, door-to-door, when using the rail (and to make the rail an attractive alternative to car). Integration depends on the extent to which the interchange between the components of the 'chain' is seamless. The EU's actions to r",{"id":641,"funder":7,"programme":8,"title":642,"piName":10,"institution":643,"country":27,"year":13,"amount":644,"abstract":645},"cordis-marie-skłodowska-curie-actions-award-6357","Beta-catenin\u002FTCF target gene programs driving intestinal Stem Cell maintenance, colorectal cancer initiation and progression","PARC CIENTIFIC DE BARCELONA (INSTITUT DE RECERCA BIOMÈDICA DE BARCELONA )","€40,000","beta-catenin\u002FTCF signalling in the intestinal epithelium controls colorectal cancer (CRC) initiation but also Stem Cell maintenance and specification. We have recently shown that paradoxically both processes are driven by the same genetic program. However, recent observations indicate that Wnt signalling might also direct a specific program in tumour cells, and that the core set of beta-catenin\u002FTCF targets shared between CRC cells and intestinal Stem Cells is further modified throughout tumorige",{"id":647,"funder":7,"programme":8,"title":648,"piName":10,"institution":649,"country":539,"year":13,"amount":650,"abstract":651},"cordis-marie-skłodowska-curie-actions-award-8807","Development and application of novel LD-based approaches for the positional cloning of quantitative trait loci in livestock","UNIVERSITY OF LIEGE","€118,505","Most medically and agronomically important traits are ¿multifactorial¿ phenotypes influenced by multiple polygenes or Quantitative Trait Loci (QTL) as well as environmental factors. Identifying the genes influencing such ¿complex¿ traits is one of the most important goals of modern genetics, as it paves the way towards numerous important medical and agricultural applications.One of the most important bottlenecks towards that goal is the difficulty to accurately determine the location of QTL on t",{"id":653,"funder":7,"programme":8,"title":654,"piName":10,"institution":510,"country":78,"year":13,"amount":655,"abstract":656},"cordis-marie-skłodowska-curie-actions-award-11192","T-cell immune response and T-cell apoptosis in Shigella infection","€158,218","Shigellosis is one of the most serious cause of diarrheal disease in the world. The global impact has been estimated at over 160 million cases per year. Shigellosis is a major cause of infant mortality in developing countries with nearly 1 million deaths p er year.Shigella infiltrate and disrupt the integrity of the intestinal epithelium, initiate an inflammatory cascade, and induces apoptosis in host phagocytes. Adaptive immunity to Shigella infection is characterised by the induction of a humo",{"id":658,"funder":7,"programme":8,"title":659,"piName":10,"institution":660,"country":55,"year":13,"amount":661,"abstract":662},"cordis-marie-skłodowska-curie-actions-award-11050","Implication of mosquito peptidoglycan recognition proteins in immune regulation and anti-malarial defence.","UNIVERSITY OF PERUGIA","€143,746","Malaria still threatens human health and economic growth on a worldwide scale. The prevalence and mortality of this disease has been estimated with 300-500 million clinical cases and over 1 million deaths each year in tropical and sub-tropical regions of t he earth. The most affected area is sub-Saharan Africa where 90% of the infections occur. Malaria control has been hampered by the lack of a valid vaccine, and the development of resistance of Plasmodium spp. to drugs and of Anopheles spp. to ",{"id":664,"funder":7,"programme":8,"title":665,"piName":10,"institution":666,"country":55,"year":13,"amount":466,"abstract":667},"cordis-marie-skłodowska-curie-actions-award-8999","Investigation of the functions of a novel protein, PRDM16, rearranged in cases of acute myeloid leukaemia with rare translocations","EUROPEAN INSTITUTE OF ONCOLOGY (ISTITUTO EUROPEO DI ONCOLOGIA)","The proposed research project plans to investigate the functions of a novel protein, PRDM16 (MEL1), in leukaemogenesis. PRDM16 is a member of the SET domain family of histone lysine methyltransferases and was recently identified by the host laboratory to be rearranged in three cases of acute myeloid leukaemia carrying rare translocations.In the first case, full length PRDM16 is aberrantly expressed, whereas in the second case, a deleted PRDM16 lacking the SET domain (delPRDM16) is formed. In the",{"id":669,"funder":7,"programme":8,"title":670,"piName":10,"institution":671,"country":55,"year":13,"amount":672,"abstract":673},"cordis-marie-skłodowska-curie-actions-award-514736","Regulation of apoptosis in fibroblast-like synoviocyte by TNF-alpha and signal transduction activation in the process","AZIENDA OSPEDALIERA ARCISPEDALE SANTA MARIA NUOVA","€152,421","Hyperplasia of synovial membrane is a hallmark of Rheumatoid Arthritis (RA), and is associated with enhanced cytokine levels, which is also a character of RA. Synovial hyperplasia is mainly due to the fibroblast-like synoviocyte (FLS)'s over-proliferation and resistance to apoptosis. TNF-alpha is a primary cytokine in the development\u002Fprogression of RA disease and is able to induce cell proliferation, activity and apoptosis. Clinicai experience has shown that anti-TNF-alpha therapy is effective w",{"id":675,"funder":7,"programme":8,"title":676,"piName":10,"institution":376,"country":78,"year":13,"amount":677,"abstract":678},"cordis-marie-skłodowska-curie-actions-award-10911","Identification of novel receptors that may substitute the TCR signal in health and disease. Analysis of the mechanisms for activation of alpha-beta and gamma-delta T cells in LAT mutant mice.","€158,786","The laboratory of B. Malissen has recently constructed knock-in mice displaying various point mutations in the adaptor protein LAT, which developed pathologies reminiscent of that of asthmatic patients developing exacerbated Th2 responses and of patients s uffering of idiopathic hypereosinophilic syndrome. One model showed early accumulation of polyclonal helper T cells that chronically produce type 2 cytokines in large amounts. In a second model, alpha-beta T cell development was blocked, but l",{"id":680,"funder":7,"programme":8,"title":681,"piName":10,"institution":682,"country":78,"year":13,"amount":10,"abstract":683},"cordis-marie-skłodowska-curie-actions-award-24864","New microfluidic strategy for protein crystallisation","ECOLE SUPéRIEURE DE PHYSIQUE ET CHIMIE INDUSTRIELLE","Obtaining protein crystals suitable for X-rays scattering is requested to resolve protein functionalities, which is one of the most important goal of biological research. In this domain, microfluidics has recently proved be a powerful, rapid and efficient approach: by rapidly screening an important number of different conditions, and exploiting scale reduction, accelerates by orders of magnitude the determination of optimal grow conditions. This approach led to crytallise for the first time inte",{"id":685,"funder":7,"programme":8,"title":686,"piName":10,"institution":609,"country":220,"year":13,"amount":10,"abstract":687},"cordis-marie-skłodowska-curie-actions-award-21748","Isolation of a master regulator of alkaloid production in Catharanthus roseus","Alkaloids form an important class of plant compounds with many pharmaceutically active compounds. The plant species Catharanthus roseus produces among other pharmaceuticals the widely used anti-cancer compounds vincristine and vinblastine. Alkaloid biosynthesis in Catharanthus is stimulated by the plant stress hormone jasmonic acid and related signalling compounds, collectively known as JAs. JAs activate the expression of alkaloid biosynthesis genes via a jasmonate- and elicitor-responsive eleme",{"id":689,"funder":7,"programme":8,"title":690,"piName":10,"institution":401,"country":20,"year":13,"amount":691,"abstract":692},"cordis-marie-skłodowska-curie-actions-award-10228","Evolution of elicitor (avirulence) genes in powdery mildew fungi (Diversity and evolution of avirulence in powdery mildews)","€168,798","The overall aim of the fellowship is to analyse the molecular evolution of a family of genes in fungi, which cause powdery mildew diseases of plants. Avirulence genes elicit host defences in gene-for-gene interactions with plants. The family to be studied is related to the Avrk1 gene in the barley mildew, Blumeria graminis f.sp. hordei.The specific objectives are:1. To research the evolution of members of the Avrk1-like gene family in diverse isolates of B. graminis hordei. This will identify el",{"id":694,"funder":7,"programme":8,"title":695,"piName":10,"institution":696,"country":33,"year":13,"amount":10,"abstract":697},"cordis-marie-skłodowska-curie-actions-award-22246","Alzheimer disease Related Functional Effects of the Urokinase-Type Plasminogen Activator (uPA) Gene PLAU","TECHNISCHE UNIVERSITÄT MÜNCHEN","Alzheimer's disease (AD) is a complex neurodegenerative disorder that causes a progressive decline of cognitive abilities. Abundant evidence suggests that elevated amounts of the small highly amyloidogenic protein beta-amyloid (Aß) contributes to the neuro degenerative process in AD. Susceptibility loci for AD have been identified on chromosome 10q. Within the proximal region (~10q21-22), the plasminogen activator urokinase gene (PLAU) has been suggested as the strongest candidate due to its fun",{"id":699,"funder":7,"programme":8,"title":700,"piName":10,"institution":701,"country":12,"year":13,"amount":10,"abstract":702},"cordis-marie-skłodowska-curie-actions-award-25128","hHR23B\u002FRad23 and its role in ubiquitin\u002Fproteasome system and DNA repair","KAROLINSKA INSTITUTE","The highly conserved Saccharomyces cerevisiae Rad23 protein was originally identified as a DNA repair factor and has several homologues, including the human hHR23A and hHR23B proteins. Early on sequence analysis suggested a role for Rad23 in the ubiquitin\u002F proteasome system (UPS), which is responsible for the degradation of redundant proteins in the cell. Rad23 has been shown to be involved in regulation of nucleotide excision repair (NER), proteolysis and cell cycle progression. The precise fun",{"id":704,"funder":7,"programme":8,"title":705,"piName":10,"institution":701,"country":12,"year":13,"amount":706,"abstract":707},"cordis-marie-skłodowska-curie-actions-award-11078","Characterization of transcription termination factors in mammalian mitochondria","€156,883","Transcription from the mitochondrial (mt) DNA H-strand promoter (HSP) produces a polycistronic precursor RNA encompassing all the genetic information encoded in that strand. Both mt rRNA genes and 12 out of 13 mRNA encoding genes are transcribed from HSP. There is a 20-fold higher expression of the rRNA gene region relative to the downstream mRNA encoding genes which involves an attenuation phenomenon just downstream of the 16S rRNA gene. A central role in this attenuation is played by mTERF, a ",{"id":709,"funder":7,"programme":8,"title":710,"piName":10,"institution":711,"country":712,"year":13,"amount":713,"abstract":714},"cordis-marie-skłodowska-curie-actions-award-8330","Methods for Real Time 3D tomography in tissue","FOUNDATION FOR RESEARCH AND TECHNOLOGY- HELLAS","EL","€129,115","Within this research project, novel and ultra-fast methods for 3D in-vivo imaging will be developed and applied to imaging in tissues and large animals such as mice. In particular, computer codes that extract 3D surfaces, and implement such surfaces for predicating the propagation of light within tissue will be developed. These codes will be used in fast inversion algorithms to provide 3D maps of absorption and\u002For fluorescence if possible in real time. The computer codes developed will be implem",{"id":716,"funder":7,"programme":8,"title":717,"piName":10,"institution":591,"country":20,"year":13,"amount":10,"abstract":718},"cordis-marie-skłodowska-curie-actions-award-25901","Scaling Limits of Brownian Coagulation","We consider a system of diffusing particles, which coagulate when they get close. Macroscopically the system is described by the long established Smoluchowski equation for the particle densities. There has been recent progress in deriving this equation from a microscopic model, given by a stochastic process for the time evolution of each individual particle. The results indicate, that the relation between microscopic and macroscopic interaction rates depends on the scaling regime of the hydrodyn",{"id":720,"funder":7,"programme":8,"title":721,"piName":10,"institution":722,"country":33,"year":13,"amount":723,"abstract":724},"cordis-marie-skłodowska-curie-actions-award-501755","Self-organized formation of atomic-size magnetic nano-wires","FRIEDRICH-ALEXANDER-UNIVERSITÄT ERLANGEN - NÜRNBERG","€47,766","This proposal has two major objectives which are: first, the self-organized creation of magnetic nanowires of atomic width and well-defined lengths as well as the creation of superlattices with the magnetic metals alternating with a non-magnetic spacer. Second, a detailed structural characterisation of these nanostructures, with picometer accuracy. The first aim will be reached with an innovative approach that exploits the flexibility of the substrate surface, instead of using the dominating tec",{"id":726,"funder":7,"programme":8,"title":727,"piName":10,"institution":728,"country":20,"year":13,"amount":167,"abstract":729},"cordis-marie-skłodowska-curie-actions-award-515472","The role of mRNA nuclear export factors in mRNA localization in the cytoplasm during Drosophila development","THE UNIVERSITY OF EDINBURGH","Asymmetric mRNA localization is a common posttranscriptional method by which cells target proteins efficiently to their site of function. In most cases, the destination of mRNAs is determined by an interaction between RNA and trans-acting factors. However, i t is unclear which trans-acting factors are universally required for mRNA export and whether different export factors may have specialized roles in the transport and localization of subpopulations of mRNAs and\u002For at different times or tissue",{"id":731,"funder":7,"programme":8,"title":732,"piName":10,"institution":733,"country":220,"year":13,"amount":734,"abstract":735},"cordis-marie-skłodowska-curie-actions-award-21510","Large-N Yang-Mills Theory","UTRECHT UNIVERSITY","€151,522","Yang-Mills theory describes the strong interactions of quarks and gluons to form particles such as the proton. It is widely acknowledged as an important outstanding problem at the frontier of physics with connections to condensed matter, mathematical & computational physics. The large N expansion is a promising method to solve the strongly coupled infrared of the theory and quantitatively test its predictions. The proposal's 1st part concerns bound states in an asymptotically free theory, Spheri",{"id":737,"funder":7,"programme":8,"title":738,"piName":10,"institution":739,"country":20,"year":13,"amount":740,"abstract":741},"cordis-marie-skłodowska-curie-actions-award-9152","Hydrophobicity, lipophilicity and bio-availability of trace metals in coastal systems","UNIVERSITY OF PLYMOUTH HIGHER EDUCATION CORPORATION","€168,232","It is widely accepted that the most chemically reactive and biologically available form of trace metal in natural environments is the free ion. For many metals, organic complexes dominate metal speciation in natural waters and the free ion comprises a relatively small fraction of total metal.Some complexes of trace metals are, however, thought to display toxic characteristics when they are sufficiently small and hydrophobic (or lipophilic) to cross the plasma membrane directly. The partitioning ",{"id":743,"funder":7,"programme":8,"title":744,"piName":10,"institution":745,"country":78,"year":13,"amount":746,"abstract":747},"cordis-marie-skłodowska-curie-actions-award-11549","Searching","INRIA - THE FRENCH NATIONAL INSTITUTE FOR RESEARCH IN COMPUTER SCIENCE AND CONTROL","€157,399","The Web in it s current form presents the following challenges:- Web data collection, storage and management is carried out mainly by few large scale commercial organizations, leading to an oligopoly if not to a monopoly in web data management and searching.- Web search is predominantly based on keyword search reducing this important procedure in a simple string matching issue while disregards broader similarity aspects such as semantics, link structures, etc.- Web data search and organization i",{"id":749,"funder":7,"programme":8,"title":750,"piName":10,"institution":751,"country":752,"year":13,"amount":753,"abstract":754},"cordis-marie-skłodowska-curie-actions-award-24072","Cosmological singularities in string theory","THE HEBREW UNIVERSITY OF JERUSALEM","IL","€165,450","The aim of this project is to study strong gravitational fields, and especially cosmological singularities, with string theory. We will use the complementary tools of world-sheet conformal field theory, to obtain a description of these space-times valid to arbitrarily high- energy scales, and gauge\u002Fgravity correspondence (holography) to go beyond perturbation theory. Scenarios of mirage cosmology will also be considered using an exact boundary conformal field theory description. The success of t",{"id":756,"funder":7,"programme":8,"title":757,"piName":10,"institution":758,"country":78,"year":13,"amount":85,"abstract":759},"cordis-marie-skłodowska-curie-actions-award-10830","Studying systematic differences between the air fluorescence technique and the surface detector technique with hybrid cosmic ray data from the Pierre Auger Observatory.","INSTITUT NATIONAL DE PHYSIQUE NUCLEAIRE ET PHYSIQUE DES PARTICULES (CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE)","The Pierre Auger Observatory (Auger) measures the ultra high energy cosmic ray flux and arrival directions indirectly by detecting the showers of charged particles that cosmic rays generate in the earth and apos;s atmosphere. These air showers are detected using two different techniques: air fluorescence detectors, like the High Resolution Fly and apos;s Eye experiment (HiRes), observe the light from excited nitrogen molecules in the path of the air shower; huge arrays of surface detectors, simi",{"id":761,"funder":7,"programme":8,"title":762,"piName":10,"institution":763,"country":33,"year":13,"amount":10,"abstract":764},"cordis-marie-skłodowska-curie-actions-award-22280","Solutions to the Witten-Dijkgraaf-Verlinde-Verlinde equations of associativity and their applications","MAX-PLANK INSTITUTE FOR MATHEMATICS, BONN","The main subject of the proposed research is the theory of Frobenius manifolds, which unifies different areas of mathematics such as the theory of singularities, quantum cohomologies of algebraic varieties, and Hurwitz spaces. From the point of view of physics, some Frobenius structures describe the moduli space of topological conformal field theories. They also appear in other areas of active current research - from random matrices to interface dynamics.The first goal of this project is to cons",{"id":766,"funder":7,"programme":8,"title":767,"piName":10,"institution":376,"country":78,"year":13,"amount":150,"abstract":768},"cordis-marie-skłodowska-curie-actions-award-23373","Gauge fields and strings","It is known that strongly coupled gauge theories have a dual, holographic, description as string or gravity theories, but the duality is well understood only for fairly unrealistic theories. This project tries to improve our understanding for more realistic cases.Concretely, the dual of QCD should be a five dimensional theory, so it is necessary to deal with strings in less than ten dimensions (the so-called non-critical strings). We plan to research in this non-critical duality. In particular, ",{"id":770,"funder":7,"programme":8,"title":771,"piName":10,"institution":772,"country":78,"year":13,"amount":10,"abstract":773},"cordis-marie-skłodowska-curie-actions-award-22097","Bridging Europe: The driving force of new engineering materials","LABORATOIRE CENTRALE DES PONTS ET CHAUSSEES","One of the challenges facing civil engineers as we enter into the new century is the progress of our infrastructures. Highways are a key element of our infrastructure and the demand of highway capacity increases annually with economic growth and increase o f population. Moreover, since many infrastructures are approaching or have exceeded their useful service lives, the existing highways and highway bridges are facing severe deterioration problem. The design of the next European infrastructure s",{"id":775,"funder":7,"programme":8,"title":776,"piName":10,"institution":777,"country":712,"year":13,"amount":778,"abstract":779},"cordis-marie-skłodowska-curie-actions-award-21982","String field Theory and new cosmological models","INSTITUTE OF PLASMA PHYSICS, DEPARTMENT OF PHYSICS, UNIVERSITY OF CRETE","€128,329","New cosmological models arising from String Field Theory will be studied. It is known from observational data that the state parameter w in cosmology is close to -1. It is suggested to use the tachyon of string field theory as a scalar field in cosmological models of the Dark Energy, because the non-local structure of the string interaction makes this field a phantom, which would realize the Dark Energy dominated Universe. Various consequences of these new cosmological models, such as an interac",{"id":781,"funder":7,"programme":8,"title":782,"piName":10,"institution":783,"country":78,"year":13,"amount":784,"abstract":785},"cordis-marie-skłodowska-curie-actions-award-8859","New integrable dynamics: from condensed matter systems to gauge and string theories","INSTITUT DES HAUTES ETUDES SCIENTIFIQUES","€144,000","There are many examples in physics when dynamics of the system in question can be shown to be integrable, i.e. entirely determined by the algebraic structure underlying its symmetries. It seems that the integrability is an emerging new principle of Nature, universal and ubiquitous. In particular, there are many recent examples of appearance of the integrable structure (exactly solvable non-linear partial differential equations) in quantum field theories (Yang-Mills theories), condensed matter sy",{"id":787,"funder":7,"programme":8,"title":788,"piName":10,"institution":789,"country":78,"year":13,"amount":10,"abstract":790},"cordis-marie-skłodowska-curie-actions-award-21337","Effect of Medicago truncatula genotype on the microbial community and the bioavailability of phosphorus in the rhizosphere","INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE","Phosphorus (P) is one of the least mobile and available soil nutrients to plants. Generally, plants require almost 10-times the concentration P available in most soils for optimal growth. Environmental concern is pressuring producers to decrease the amount of P fertilisers applied to soils. Using P-efficient plant genotypes that can adequately grow in low P soils may be an alternative to P fertilisers. Mechanisms which increase P availability to plants include proton release (root-induced acidif",{"id":792,"funder":7,"programme":8,"title":793,"piName":10,"institution":794,"country":61,"year":13,"amount":795,"abstract":796},"cordis-marie-skłodowska-curie-actions-award-9922","Graph theory and general topology: foundations, infinite graphs and beyond","DANMARKS TEKNISKE UNIVERSITET (TECNICAL UNIVERSITY OF DENMARK)","€147,466","In spite of the traditional gap between graph theory and topology, it is possible to view a graph as a (possibly finite) non-trivial topological object.With respect to this novel topology, the ground set consists of the vertices and edges of the graph, so that an edge is as much of a 'point' in the space as a vertex is, in contrast with the traditional way of modelling a graph as a one-dimensional cell-complex.This topological construction reduces graph-theoretic connectedness directly to connec",{"id":798,"funder":7,"programme":8,"title":799,"piName":10,"institution":800,"country":78,"year":13,"amount":10,"abstract":801},"cordis-marie-skłodowska-curie-actions-award-22357","Theoretical analysis of nonperturbative QCD effects in heavy quark systems","UNIVERSITE PARIS-SUD XI","The project is aimed at the theoretical analysis of the effects of strong interactions in weak processes with hadrons containing the heavy beauty b-quark. Weak interactions of the b-quark give a possibility to probe a fundamental property of nature - a difference between matter and antimatter, known as CP violation. They also allow a measurement of the unknown parameters of the Standard Model describing the mixing between the heavy and the light quarks, and open a window to physics beyond the St",{"id":803,"funder":7,"programme":8,"title":804,"piName":10,"institution":805,"country":78,"year":13,"amount":806,"abstract":807},"cordis-marie-skłodowska-curie-actions-award-22927","Extremal Problems in Fourier Analysis and Applications","CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE","€148,339","We plan to explore systematically a number of closely related problems, using recent techniques of Fourier analysis. Key topics are positive definite functions, uncertainty principles, and duality theory in, say, locally compact groups. Wide interest in an d current flourishing of Fourier analysis and in particular extremal problems stem from applications, ranging even to far fields of science, from mathematical areas as number theory, geometry and analysis, to applied mathematics including nume",{"id":809,"funder":7,"programme":8,"title":810,"piName":10,"institution":811,"country":20,"year":13,"amount":277,"abstract":812},"cordis-marie-skłodowska-curie-actions-award-10326","Towards Rational Zeolite Design","ROYAL INSTITUTION OF GREAT BRITAIN","In the proposed project I aim to develop a set of design tools to guide the synthesis of new zeolite-like frameworks, through a thorough understanding of the link between framework topology and energetics. Zeolites and related crystalline microporous solid s constitute an industrially important class of materials with significant applications as catalysts, adsorbents and ion-exchangers. The wide scope of their use originates from the fact that they span a uniquely large spectrum of easily synthe",{"id":814,"funder":7,"programme":8,"title":815,"piName":10,"institution":816,"country":259,"year":13,"amount":10,"abstract":817},"cordis-marie-skłodowska-curie-actions-award-25261","Structural elucidation by x-ray crystallography of p62, a nuclear pore subcomplex involved in signal mediated nucleocytoplasmic transport","DEPARTMENT OF STRUCTURAL BIOLOGY, BIOZENTRUM, UNIVERSITY OF BASEL, SWITZERLAND","Nuclear pore complexes (NPCs) are large multi-protein structures (~125 MDa) spanning the double membrane of the nucleus and acting as the only gateway of nucleocytoplasmic transport. The three dimensional (3D) architecture of the NPC, its role in trafficking of proteins and RNA, and its molecular composition (nucleoporins 'Nups') have been extensively studied.Nonetheless, to understand how the NPC mediates nucleocytoplasmic exchange requires the independent characterization of its molecular comp",{"id":819,"funder":7,"programme":8,"title":820,"piName":10,"institution":821,"country":220,"year":13,"amount":822,"abstract":823},"cordis-marie-skłodowska-curie-actions-award-3093","Geometric quantization of field theories","STICHTING KATHOLIEKE UNIVERSITEIT","€143,038","Quantum field theories are the basis of most of modern theoretical physics, but they are not well understood mathematically. Although algebraic quantum field theory provides a framework for describing quantum field theories mathematically, there has been little success at constructing specific models, particularly of gauge theories.On the other hand, the relationship between classical and quantum mechanics has been abstracted and studied in terms of deformation quantization, and the construction",{"id":825,"funder":7,"programme":8,"title":826,"piName":10,"institution":827,"country":33,"year":13,"amount":828,"abstract":829},"cordis-marie-skłodowska-curie-actions-award-25597","Role of palladin for actin filament organization in podocytes foot processes","ERNST MORITZ ARNDT UNIVERSITY GREIFSWALD","€148,588","Podocytes are injured in many forms of human and experimental glomerular disease such as focal segmental glomelurosclerosis, diabetic nephropathy, and crescentic glomerulonephritis. The singularity of the actin cytoskeleton in podocytes and its critical role for podocyte function is well known.Indeed, podocytes express unique actin-associated proteins such as synaptopodin, mutation or absence of alfa-actinin-4 result in glomerulosclerosis due to podocyte loss by unknown reasons, and several stim",{"id":831,"funder":7,"programme":8,"title":832,"piName":10,"institution":376,"country":78,"year":13,"amount":833,"abstract":834},"cordis-marie-skłodowska-curie-actions-award-514982","GlutathloNe and gene regulation","€149,103","Legumes are one of the most important crops, providing the major source of proteins and oil and improving the nitrogen soil fertilization. Glutathione (GSH) and its legume specific homologue, homoglutathione (hGSH), are major antioxidant molecules, which have important roles in plant defence against biotic and abiotic stresses, storage of reduced sulphur and redox control of the cell. Recently, our team has shown that these molecules have a key role in the nodulation process of legumes. GINGER w",{"id":836,"funder":7,"programme":8,"title":837,"piName":10,"institution":838,"country":55,"year":13,"amount":839,"abstract":840},"cordis-marie-skłodowska-curie-actions-award-7623","Laplacian growth and inverse potential problems","SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI","€145,617","In the last twenty years much efforts have been done in the understanding of interface dynamics in various fields, such as hydrodynamics, combustion, non-equilibrium statistical and condensed matter physics. The problem of pattern formation is one of the most rapidly developing branches of non-linear science today. The field has grown fast and there is no need to stress its importance. The study of the front dynamics between two phases (Laplacian growth problem) that arises in a variety of non-e",{"id":842,"funder":7,"programme":8,"title":843,"piName":10,"institution":844,"country":220,"year":13,"amount":845,"abstract":846},"cordis-marie-skłodowska-curie-actions-award-24392","Nonlocal computational homogenization","TECHNISCHE UNIVERSITEIT EINDHOVEN","€75,489","Almost every natural as well as industrial material displays a heterogeneous structure on several scales of observation. The individual phases present in these material systems define the material microstructure. Properties of the microstructural constituents together with the character of applied loading determine the macroscopic behaviour of these multi-phase material systems. Multi-scale modelling is a recent multi-disciplinary research discipline that aims to describe and predict the macrosc",{"id":848,"funder":7,"programme":8,"title":849,"piName":10,"institution":850,"country":61,"year":13,"amount":851,"abstract":852},"cordis-marie-skłodowska-curie-actions-award-515536","Benthic invertebrate guts as mobile microsites in sediments: Hot spots for denitrification and N2O production","UNIVERSITY OF AARHUS","€20,500","The proposed project centres on so far neglected animal-microbe interactions in freshwater sediment that are expected to greatly influence denitrification rates and N2O emission to the atmosphere. We hypothesise that the guts of sediment-dwelling detritivores constitute mobile microsites in which bacterial denitrification will be induced by anoxia and high concentrations ofdissolved organic carbon. Over time, the inoculation of sediment with actively denitrifying bacteria via egested feces may f",{"id":854,"funder":7,"programme":8,"title":855,"piName":10,"institution":856,"country":20,"year":13,"amount":857,"abstract":858},"cordis-marie-skłodowska-curie-actions-award-514549","Catalytic cascade reactions, generic technology for glycobiology","UNIVERSITY OF LEEDS","€160,180","Innovative chemical manipulation of carbohydrates has lagged significantly behind advances in glycobiology (the biochemistry of carbohydrates). Moreover, despite the widespread involvement of carbohydrates in the fundamental processes underpinning human an d animal health and their involvement in the growth and maturation of many of the species responsible for human\u002Fanimal illness, e.g. bacteria, viruses, there has not been a concerted and substantial involvement of major pharmaceutical \u002Fanimal ",{"id":860,"funder":7,"programme":8,"title":861,"piName":10,"institution":591,"country":20,"year":13,"amount":857,"abstract":862},"cordis-marie-skłodowska-curie-actions-award-10501","Crystallographic studies of bacterial membrane transport systems","This project will study substrate translocation mechanisms of multi-component drug-efflux pumps that transport molecules across membranes in Gram-negative bacteria. These pumps serve both protective and virulence associated functions, by forming channels associated with the export of invasive proteins and the efflux of toxic compounds. At the same time, the outer membrane component of the pump, TolC, is a point of weakness for the bacterium since it is a receptor for bacteriophages and is a poin",{"id":864,"funder":7,"programme":8,"title":865,"piName":10,"institution":866,"country":27,"year":13,"amount":867,"abstract":868},"cordis-marie-skłodowska-curie-actions-award-22164","Artificial symbiosis for the cultivation of marine invertebrate-associated bacteria","CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","€251,595","This proposal deals with the cultivation of the symbiotic bacteria that are associated with marine sponges. Marine sponges belong to richest and most diverse organisms with respect to their symbiotic microbial population. In addition, marine sponges belon g to the most interesting natural sources of metabolites with anticancer activity. From a number of the most promising metabolites it has been established that they are actually produced by the bacterial symbionts. Currently, less than 1 % of t",{"id":870,"funder":7,"programme":8,"title":871,"piName":10,"institution":872,"country":78,"year":13,"amount":873,"abstract":874},"cordis-marie-skłodowska-curie-actions-award-514535","Antigen presentation and T cell-mediated immunity: membrane trafficking in cross-presentation","INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE","€151,938","Cross presentation is the process by which professional antigen presenting cells (APCs) present phagocyted antigens in the context of MHC class I molecules (MHC I), to prime CD8+ T cells. Recent findings have revealed that this process takes place in a spe cialized, ER-phagosome mix compartment in the major APCs, like dendritic cells (DCs) and macrophages. This novel compartment was also shown to be self-sufficient for cross presentation. In this context, ER membranes are recruited to the formin",{"id":876,"funder":7,"programme":8,"title":877,"piName":10,"institution":878,"country":412,"year":13,"amount":10,"abstract":879},"cordis-marie-skłodowska-curie-actions-award-23750","Development of novel analytical method for complex determination of organic compounds in Aerosols Participating on global changes in atmosphere","HELSINGIN YLIOPISTO","Aerosol particles are ubiquitous and influence our life directly by inhalation, or indirectly by contribution to climate changes. Knowledge of organic content of the aerosol particles is crucial for specification of their source, and for monitoring of their fate. This proposal suggests novel approach for complex determination of organic species in aerosol particles.The aerosol particles will be deposited by an impactor, a device for precise and selective aerosol collection. Extraction of the org",{"id":881,"funder":7,"programme":8,"title":882,"piName":10,"institution":883,"country":27,"year":13,"amount":10,"abstract":884},"cordis-marie-skłodowska-curie-actions-award-25521","Influence of selective grazing of bacteria on the transfer of autochthonous versus allochthonous carbon","INSTITUTO MEDITERRANEO DE ESTUDIOS AVANZADOS, CSIC-UNIV. ILLES BALEARS","In brief, the proposed project is about the influence of selective grazing of marine bacteria on the transfer of autochthonous versus allochthonous carbon. It appears that there are different bacterial life strategies - fast growth on high quality substrates and high sensitivity to grazing, and slow growth on low quality substrates and low sensitivity to grazing.Due to qualitative differences in dissolved organic matter (DOM) of autochthonous and allochthonous origin, the selective grazing of ba",{"id":886,"funder":7,"programme":8,"title":887,"piName":10,"institution":888,"country":20,"year":13,"amount":889,"abstract":890},"cordis-marie-skłodowska-curie-actions-award-7541","New Heterocyclic Liquid Crystals","UNIVERSITY OF EXETER","€23,814","This proposal will bring to the EU a most talented Russian researcher with a strong background in heterocyclic chemistry, and to use his expertise in a ped with the synthesis and properties of new heterocyclic liquid crystals. In one part, the work will exploit the availability of precursors to symmetric and unsymmetric di- and tri-substituted phenanthrolines to realise high birefringence materials with negative dielectric anisotropy, while in another, bent-core disubstituted phenanthrolines wil",{"id":892,"funder":7,"programme":8,"title":893,"piName":10,"institution":894,"country":55,"year":13,"amount":895,"abstract":896},"cordis-marie-skłodowska-curie-actions-award-8985","Active manipulation of Biomolecules in microfluidic arrays","SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA","€72,156","The proposed research deals with the problem of sorting and separating biomolecules using a microfluidic network of micron- or nanometre-sized channels. The flow in the network is driven by electrical potentials induced by electrodes placed at various node s of the network. We propose to carry out a comprehensive study (both analytical and computational) of the resulting electroosmotic flow (EOF) in the network in order to determine the channel configuration and the electric potential distributi",{"id":898,"funder":7,"programme":8,"title":899,"piName":10,"institution":545,"country":20,"year":13,"amount":277,"abstract":900},"cordis-marie-skłodowska-curie-actions-award-10311","Structural studies of the catalytic core of the spliceosome","The excision of introns from eukaryotic pre-mRNA and splicing together of exons is performed by a macromolecular machine called the spliceosome. Splicing is a highly dynamic process that involves many spliceosomal intermediates. Each intermediate contains specific RNA-protein complexes called small nuclear ribonucleoprotein particles (snRNPs) and a number of additional non-snRNP proteins. It has been established that the spliceosome intermediates that are involved in the actual splicing reaction",{"id":902,"funder":7,"programme":8,"title":903,"piName":10,"institution":904,"country":33,"year":13,"amount":10,"abstract":905},"cordis-marie-skłodowska-curie-actions-award-24162","Parkinson's disease: vulnerability of dopaminergic neurons by Pink 1 versus Parkin mutations in mice","KLINIKUM DER JOHANN WOLFGANG GOETHE-UNIVERSITäT \u002F FRANKFURT AM MAIN","Parkinson's disease (PD) is the second most frequent neurodegenerative disorder in the aging European society. It is characterized by the preferential degeneration of dopamine (DA)-signalling neurons in the midbrain. Autosomal recessive inheritance of par ticularly early manifesting PD with unusually long therapeutic benefit from dopamine substitution has been traced to mutations in the PARK2 (parkin) protein and the PARK6 (Pink1) protein. Analyses of patients' tissue and genetic animal models i",{"id":907,"funder":7,"programme":8,"title":908,"piName":10,"institution":909,"country":33,"year":13,"amount":10,"abstract":910},"cordis-marie-skłodowska-curie-actions-award-25471","Mimicking cadherin-mediated cell adhesion","UNIVERSITY OF HEIDELBERG","Cell adhesion is considered to play an important role in many biological functions such as the regulation of organ and tissue development during embryogenesis, and the maintenance of normal tissue structure in the adult organism.The specificity of cell-adhesion is controlled by genetic expression of receptors at the cell surface, which bind to ligand molecules of target cells or tissue by lock-and-key principles. The cadherins, membrane-spanning glycoproteins, initiate intercellular junctions by",{"id":912,"funder":7,"programme":8,"title":913,"piName":10,"institution":914,"country":33,"year":13,"amount":915,"abstract":916},"cordis-marie-skłodowska-curie-actions-award-9293","Analysis of single molecules at high concentration in stimulated emission depletion generated zeptoliter volumes with fluorescence correlation spectroscopy","MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.","€149,155","The objective of this proposal comes from a wish and need in fluorescence-based bioanalytical studies to detect single molecules, one by one, even at high biological concentrations.At present, commonly used optical microscopes applied in the detection of single molecules, using diffraction-limited observation volumes (lateral size ~200nm; axial ~ 500 nm), only allow for single molecules to be detected at pico- to nanomolar concentrations. The aim of the proposal is to develop a new tool that mak",{"id":918,"funder":7,"programme":8,"title":919,"piName":10,"institution":920,"country":78,"year":13,"amount":921,"abstract":922},"cordis-marie-skłodowska-curie-actions-award-21422","THE GENERATION OF CD8 T CELL MEMORY","UNIVERSITE RENE DESCARTES PARIS 5","€147,969","CD8+ T cells are fundamental targets for improved vaccination strategies, since they are fundamental to virus and tumors control, and current immunization protocols to generate efficient CD8+ responses are essentially inadequate. Major handicaps are the l ack of correlation between the current tests used to study CD8+ T cell function and infection out-come or efficient memory generation. The present project will study responses and memory using new methodological advancements that should allow e",{"id":924,"funder":7,"programme":8,"title":925,"piName":10,"institution":376,"country":78,"year":13,"amount":85,"abstract":926},"cordis-marie-skłodowska-curie-actions-award-10103","Self-hidden Bifunctional Organocatalysts for Organic Synthesis","The research project aims at developing new tools for synthetic chemistry, more precisely a new class of multi-centre catalysts (MCC). This approach markedly differs from those reported so far since the two active sites of the catalysts would mutually and reversibly protect each other via an intramolecular donor-acceptor interaction. Accordingly, the bifunctional derivatives would behave as self-hidden or dormant catalysts. Thanks to this methodology, a broader range of active sites could be inv",{"id":928,"funder":7,"programme":8,"title":929,"piName":10,"institution":930,"country":20,"year":13,"amount":931,"abstract":932},"cordis-marie-skłodowska-curie-actions-award-8966","Infant speech segmentation and the role of the emergent lexicon","UNIVERSITY OF WALES BANGOR","€114,664","The goal of the project is to bring to Europe for one year an innovative researcher in mid-career who has established a strong collaborative link with one researcher in the UK (the project host). The researcher stands to gain momentum and visibility in his career as well as to forge valuable new contacts with members of the European research community.His presence will also serve as a further stimulus to the vibrant international team of young researchers currently involved in developing a model",{"id":934,"funder":7,"programme":8,"title":935,"piName":10,"institution":936,"country":20,"year":13,"amount":10,"abstract":937},"cordis-marie-skłodowska-curie-actions-award-25654","Application of recombinant lactic acid bacteria secreting Interleukine12 for enhancement of Th1 response and alleviation of allergic disease","INSTITUTE OF FOOD RESEARCH","Common allergic disease has trebled in the last twenty years, resulting in approximately one-fifth of the EU population likely to be seeking treatment for allergy. Potentially life-threatening conditions such as peanut allergy now affect about one in 70 children and are still increasing.Asthma, rhinitis and eczema have increased two- to three-fold in the last twenty years. The cytokine IL12 is one of the most powerful Th1 lymphokines and it has been found to cure Th2 cytokine-mediated murine sch",{"id":939,"funder":7,"programme":8,"title":940,"piName":10,"institution":941,"country":78,"year":13,"amount":10,"abstract":942},"cordis-marie-skłodowska-curie-actions-award-25241","Speciated Isotope Labelling Experiments on Organometallic Compounds to Unravel their Chemical and Microbial Fate in the Environment","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE DéLéGATION RéGIONALE 15","As reflected in the Water Framework Directive (2000\u002F60\u002FEC) and in the Decision 2455\u002F2001\u002FEC the European Union has demonstrated its concern in the field of water policy, particularly in the establishment of a list of the most hazardous pollutants for the aquatic environment.Organometallic species such as tributyltin and its degradation products, Hg and its compounds as well as Pb and its compounds have been already included in this list and qualified as priority pollutants.Unravelling the biogeo",{"id":944,"funder":7,"programme":8,"title":945,"piName":10,"institution":946,"country":27,"year":13,"amount":10,"abstract":947},"cordis-marie-skłodowska-curie-actions-award-23567","Diversity of subsoil anaerobic microorganisms and their potential for aromatic hydrocarbons degradation","ESTACIóN EXPERIMENTAL DEL ZAIDíN, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTíFICAS","The steps involved in oil refining can generate accidental spills resulting in hydrocarbon contaminated areas, reaching as far as the subsoil and ground waters. Rehabilitation by microbial methods has been recognised as novel, cleaner and less expensive than physical-chemical techniques.However, low or zero oxygen levels has limited the application of aerobic bacteria in the subsoil. Consequently, anaerobes significance became apparent for subsurface bioremediation. Nevertheless, evaluation of a",{"id":949,"funder":7,"programme":8,"title":950,"piName":10,"institution":510,"country":78,"year":13,"amount":557,"abstract":951},"cordis-marie-skłodowska-curie-actions-award-8977","Analysis of interactions between cell division proteins","Cell division is a fundamental process that allows the multiplication of all bacteria. Although this mechanism is essential for their survival, it is one of the least understood processes in bacterial cell biology. Understanding the molecular function of different factors implicated in this key event of the bacterial cell cycle is essential. Furthermore the characterization of cell division machinery will open up new opportunities in bioengineering and development of novel therapeutic and antiba",{"id":953,"funder":7,"programme":8,"title":954,"piName":10,"institution":955,"country":33,"year":13,"amount":10,"abstract":956},"cordis-marie-skłodowska-curie-actions-award-24534","Biomimetic formation of bacterial magnetic nanoparticles: progress and promises","MAX PLANCK INSTITUT FüR MARINE MIKROOBIOLOGIE","One of the most intriguing examples for biogenic magnetic nanoparticles (MNPs) is found in magnetotactic bacteria (MTB). MTB synthesize intracellular, enveloped crystals of magnetite (Fe3O4) called magnetosomes, which are formed by a process called biologically-controlled mineralization (BCM). Because of unique features, BCM of magnetosomes has been in the focus of strong interdisciplinary interest to understand bacterial control on MNPs formation. However, little is known about how BCM occurs a",{"id":958,"funder":7,"programme":8,"title":959,"piName":10,"institution":960,"country":33,"year":13,"amount":961,"abstract":962},"cordis-marie-skłodowska-curie-actions-award-509865","String-of-pearls: a new bacterial consortium: investigations of lipid biomarkers and their geological significance","UNIVERSITAET BREMEN","€157,641","The proposed project is an investigation of a newly discovered consortium comprising a novel group of SM1- Archaea and bacterium, mainly Thiothrix, that takes on the appearance of a string-of-pearls.Objects bearing a close physical resemblance to these consortia have been found in rocks as old a 1500 million years and are presently considered 'problematic' fossils because there have been no known modern analogues for comparative study. In this project we will investigate the physiology and metab",{"id":964,"funder":7,"programme":8,"title":965,"piName":10,"institution":966,"country":259,"year":13,"amount":967,"abstract":968},"cordis-marie-skłodowska-curie-actions-award-8656","Nanostructured Electron Heat Engines","UNIVERSITé DE GENèVE","€179,485","In the last two years, nanostructures such as quantum dot superlattices have been experimentally demonstrated to have enormous promise as high efficiency thermoelectric materials, however why such high efficiencies can be obtained with these materials is not yet clearly understood. The applicant has previously demonstrated that nanostructured thermionic electron heat engines can operate with Carnot efficiency when the energy range of electrons transmitted through the device is infinitesimally na",{"id":970,"funder":7,"programme":8,"title":971,"piName":10,"institution":972,"country":539,"year":13,"amount":10,"abstract":973},"cordis-marie-skłodowska-curie-actions-award-23702","Role of interfacial rheology in tailoring the stability of Pickering emulsions","KATHOLIEKE UNIVERSITEIT LEUVEN","The goal of this project is to elucidate the role of interfacial rheology of particle-laden interfaces in the stability of Pickering emulsions, polymer blends and foams.To this end, novel interfacial rheometrical methods will be used in combination with rheo-physical methods to evaluate the influence of interfacial rheology and underlying microstructure on the stability of particle stabilized emulsions, blends or foams.Specifically, experiments on model systems will be used to establish a relati",{"id":975,"funder":7,"programme":8,"title":976,"piName":10,"institution":977,"country":20,"year":13,"amount":39,"abstract":978},"cordis-marie-skłodowska-curie-actions-award-9382","REMOTE CONFORMATIONAL CONTROL","VICTORIA UNIVERSITY OF MANCHESTER","Stereochemistry can be viewed as binary information, and stereocontrol as the communication of that information through space. Reliable stereochemical control is mediated by conformation, and empirically it is clear that better control of conformation yields higher stereoselectivity.   In this project we propose to develop the methods of stereocontrol and apply them more generally to the problem of communicating information through space, mediated not by electronics but by conformation. We shall",{"id":980,"funder":7,"programme":8,"title":981,"piName":10,"institution":972,"country":539,"year":13,"amount":982,"abstract":983},"cordis-marie-skłodowska-curie-actions-award-515608","Identification and characterization of novel genetic defects in unsolved Congenital Disorders of N-glycosylation type II (CDG-IIx) patients","€12,285","Glycobiology is considered as an emerging field of biology and the importance of complex carbohydrates in health and disease is increasingly recognized. In the last decade, a new group of diseases related to defects of glycosylation and called Congenita l Disorders of Glycosylation (CDG) has been identified. CDG can be divided into two groups according to the molecular defects, CDG-Iand CDG-II. Group I disorders relate to defects in the synthesis of the N-glycan in the endoplasmicreticulum.This ",{"id":985,"funder":7,"programme":8,"title":986,"piName":10,"institution":510,"country":78,"year":13,"amount":987,"abstract":988},"cordis-marie-skłodowska-curie-actions-award-23407","Biofilm formation in the uropathogenic Escherichia coli strain CFT073: identification of cryptic adhesion factors","€113,670","The bacterium Escherichia coli is one of the best-studied free-living organisms. However, extensive genotypic differences exist between E. coli species, likely due to differences in lifestyle, some strains being harmless commensals whereas others are serious human pathogens.Completed genome sequences of different E. coli strains have revealed that a high percentage of these genes still have unassigned or poorly characterized function. Current hypotheses consider that this could be partly due to ",{"id":990,"funder":7,"programme":8,"title":991,"piName":10,"institution":992,"country":78,"year":13,"amount":85,"abstract":993},"cordis-marie-skłodowska-curie-actions-award-9929","Structural characterization of the type III secretion translocon of Pseudomonas aeruginosa","COMMISSARIAT À L'ENERGIE ATOMIQUE","Bacterial pathogens have developed highly specialized processes to target hosts and establish infection. A recently described weapon, the type III secretion system, transfers toxins from the bacterial cytoplasm into the host cell through a pore formed on the host cell membrane upon cell-to-cell contact. In this project, we will use X-ray crystallography to study PopB and PopD, the two membrane proteins required for pore formation by the nosocomial pathogen Pseudomonas aeruginosa, both in their i",{"id":995,"funder":7,"programme":8,"title":996,"piName":10,"institution":997,"country":20,"year":13,"amount":39,"abstract":998},"cordis-marie-skłodowska-curie-actions-award-22951","Role and regulation of FOXO transcription factors in development of breast cancer and drug resistance.","IMPERIAL COLLEGE OF LONDON","To examine if FOXO expression and activity are regulated by chemotherapeutic agents (eg. cisplatin and taxol) in breast cancer cell lines",{"id":1000,"funder":7,"programme":8,"title":1001,"piName":10,"institution":361,"country":20,"year":13,"amount":1002,"abstract":1003},"cordis-marie-skłodowska-curie-actions-award-501422","Gravitating Vertex Models","€152,809","The construction of a quantum field theory of gravity is among the most fundamental open challenges in theoretical physics. Dynamical triangulations (DT) provide a discrete, non-preservative proposal for addressing this problem. These are well understood for Euclidean signature space times. However, the construction of such a framework for Corinthian signature with a dynamically evolving global causality has not yet been accomplished. As an alternative to the approach of Am Bjorn et al. using tr",{"id":1005,"funder":7,"programme":8,"title":1006,"piName":10,"institution":1007,"country":539,"year":13,"amount":10,"abstract":1008},"cordis-marie-skłodowska-curie-actions-award-21817","Foundation and justification of values in Aristotle's ethics","UNIVERSITE CATHOLIQUE DE LOUVAIN","Aristotle is often criticized for not having treated the question, essential in modern philosophy, of the foundation and justification of values that correspond to what Aristotle calls the virtues. It is true that one doesn't find any explicit and developed treatment of this question in Aristotle's work. But are three main areas where we can reconstruct the Aristotelian response to that question: the theme of the happiness as the end of virtues; the theme of the person of practical wisdom presen",{"id":1010,"funder":7,"programme":8,"title":1011,"piName":10,"institution":1012,"country":55,"year":13,"amount":839,"abstract":1013},"cordis-marie-skłodowska-curie-actions-award-8024","Renewables contribution and a framework for quantification of energy security","FONDAZIONE ENI ENRICO MATTEI","Energy is vital for all aspects of modern life and the security of energy supply has always been of strategic importance. Needless to say, the issues of energy are of critical importance in economic, environmental and social terms for sustainable development. However, the broad outlook at energy security has dramatically changed during the past few years because of a range of issues: Oil price spikes and sharp increase in gas prices; the impact of the oil products blockade in late 2000; the cris",{"id":1015,"funder":7,"programme":8,"title":1016,"piName":10,"institution":376,"country":78,"year":13,"amount":833,"abstract":1017},"cordis-marie-skłodowska-curie-actions-award-011189","Robustness of vulva development in Caenorhabditis elegans","All organisms have to maintain great phenotypic stability (robustness) in the face of numerous changes in their internal and external environment. However, despite its universal significance, it is far from clear how development has evolved to ensure a stable and reproducible phenotype when development is perturbed. To gain a better understanding of the mechanisms providing robustness, we will examine the developmental mechanisms underlying the expression of an invariant and reproducible phenoty",{"id":1019,"funder":7,"programme":8,"title":1020,"piName":10,"institution":1021,"country":20,"year":13,"amount":1022,"abstract":1023},"cordis-marie-skłodowska-curie-actions-award-515316","Role of TGF-B pathway in tumourigenesis","CANCER RESEARCH UK","€158,480","TGF-ss signalling pathways play an important role in embryonic development as well as intumouri genesis. TGF-ss signalling results in nuclear accumulation of active Smads complexes that regulate transcription of target genes. Alteration of certain TGF-ss pathway components is a frequent event in some human tumours such as colorectal or pancreatic tumours and mainly results from mutation or deletion of either the TGF-ss type II receptor or the Smad4 genes. More frequently however, human tumours t",{"id":1025,"funder":7,"programme":8,"title":1026,"piName":10,"institution":1027,"country":220,"year":13,"amount":10,"abstract":1028},"cordis-marie-skłodowska-curie-actions-award-24676","Geometry of non-Abelian effective brane theories","CTN (CENTER FOR THEORETICAL PHYSICS) UNIVERSITY OF GRONINGEN","The proposed research is to apply recent ideas from mathematics and theoretical physics in a superspace setting. These ideas concern the differential geometry one encounters when dealing with extended objects rather than points. This should shed light on the long outstanding problem of the effective action of coincident branes, i.e. generalisations of Yang-Mills theories.The use of superspace in this novel mathematical setting seems essential to achieve this. This is a completely new approach to",{"id":1030,"funder":7,"programme":8,"title":1031,"piName":10,"institution":1032,"country":55,"year":13,"amount":10,"abstract":1033},"cordis-marie-skłodowska-curie-actions-award-25053","Cosmological and phenomenological studies of string theory","SCUOLA NORMALE SUPERIORE DI PISA","String theory is for the moment a unique candidate for a consistent unification of gravity with gauge interactions but it lacks experimental evidence. Given the multitude of possible ways of compactifying string theory from ten to four dimensions, it then becomes very difficult to find the compactification that will correspond in the low energy limit to the Standard Model.One aim of the project is to make advances in understanding the way in which the Standard Model is possibly embedded as a low",{"id":1035,"funder":7,"programme":8,"title":1036,"piName":10,"institution":1037,"country":20,"year":13,"amount":1038,"abstract":1039},"cordis-marie-skłodowska-curie-actions-award-23027","The role of reproductive hormones and gestation in bile homeostasis.","IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE","€167,664","Cholestasis, the impairment of bile flow, causes liver damage via accumulation of toxic compounds in the liver and is a common and devastating manifestation of liver disease. Obstetric cholestasis (OC) is a reversible form of cholestasis, associated with major adverse pregnancy outcomes, including prematurity and intrauterine death and is caused by an imbalance in bile homeostasis due to genetic and hormonal factors. Heterozygous maternal mutations in hepato-canalicular transporters and the bile",{"id":1041,"funder":7,"programme":8,"title":1042,"piName":10,"institution":1043,"country":20,"year":13,"amount":1002,"abstract":1044},"cordis-marie-skłodowska-curie-actions-award-502356","Aspects of string gravity and cosmology","UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION","The impressive level of precision in fields such as observational cosmology and experimental gravity represent an exciting challenge and a precious test for both theoretical cosmology and fundamental physics. In order to constrain the candidate theories for unifying all interactions, the observable implications of such theories on cosmology need to be examined in detail. My research project moves in this direction and aims to study some aspects of the (linear and non-linear) gravitational field ",{"id":1046,"funder":7,"programme":8,"title":1047,"piName":10,"institution":1048,"country":20,"year":13,"amount":10,"abstract":1049},"cordis-marie-skłodowska-curie-actions-award-21568","Finite temperature field theory on the light-cone","UNIVERSITY OF WALES SWANSEA, DEPARTMENT OF PHYSICS","This proposal includes a two-year stay at SLAC under the supervision of Prof. S. Brodsky and a subsequent stay at the University of Wales, where the scientist in charge will be Dr. S. Dalley. Both are leading experts in quantum field theories on the light -cone. Light-cone quantization provides an elegant and promising method for solving the outstanding problems in quantum field theories like e.g. bound states and phase transitions in QCD.An approach to finite temperature field theory on the lig",{"id":1051,"funder":7,"programme":8,"title":1052,"piName":10,"institution":1053,"country":61,"year":13,"amount":10,"abstract":1054},"cordis-marie-skłodowska-curie-actions-award-24238","Gravity, strings and the dynamics of strongly coupled gauge theories","THE NIELS BOHR INSTITUTE, UNIVERSITY OF COPENHAGEN","The study of holographic duals has yielded and will continue to yield very interesting information about the structure of string theory and gauge theory. Within this setting, the ultimate goals of this project are the following:(1) to explore the phase structure of near-external branes (in the presence of compact directions) and the consequences of this structure for thermal physics of non-gravitational theories,(2) to obtain more information about the structure of Little String Theories and non",{"id":1056,"funder":7,"programme":8,"title":1057,"piName":10,"institution":1058,"country":33,"year":13,"amount":1059,"abstract":1060},"cordis-marie-skłodowska-curie-actions-award-514697","Effect of the local isoform of IGF on epidermal stem cells, aging and skin diseases","EUROPEAN MOLECULAR BIOLOGY LABORATORY","€144,313","The skin is the first line of defence to protect the body from dehydratation, injury and infection. The epidermis, the outer covering of the skin, is maintained throughout life by stem cells. The Rosenthal group has recently reported that a local isoform o f IGF-1 (mIGF-1) is able to enhance both skeletal muscle and heart regeneration, inducing the proliferation of a specific cell population in the bone marrow and enhancing their recruitment to the site of injury and their fusion with existing m",{"id":1062,"funder":7,"programme":8,"title":1063,"piName":10,"institution":1064,"country":259,"year":13,"amount":10,"abstract":1065},"cordis-marie-skłodowska-curie-actions-award-25272","Probes for protease activity based on fluorescent peptide dendrimers","UNIVERSITäT BERN","This project seeks to find specific peptide dendrimers through combinatorial chemistry, to be used as highly specific, fluorogenic protease substrates. A general approach is formulated that should allow to discover fluorescent dendrimer probes specific of any given protease. To that extent, combinatorial synthesis of dendrimers incorporating target sequences for well-known proteases will be carried out.Then, a suitable FRET (fluorescence resonance energy transfer) strategy for protease activity ",{"id":1067,"funder":7,"programme":8,"title":1068,"piName":10,"institution":1069,"country":20,"year":13,"amount":10,"abstract":1070},"cordis-marie-skłodowska-curie-actions-award-24800","Lactococcus lactis as a delivery system of macrophage Migration Inhibitory Factor (MIF) to enhance mucosal transport of biologically active compounds","INTITUTE OF FOOD RESEARCH","In order to induce a robust and effective immune response at mucosal level, bacteria, viruses and other antigens must cross the intestinal barrier. Highly specialised antigen-sampling M cells are strategically located in certain areas of the gut and play a fundamental role in the induction of mucosal and systemic immune responses by transporting antigens to the mucosal-associated immune system (MALT). Large numbers of in vivo studies, in which the follicle-associated epithelium (FAE) of gut-asso",{"id":1072,"funder":7,"programme":8,"title":1073,"piName":10,"institution":1074,"country":78,"year":13,"amount":10,"abstract":1075},"cordis-marie-skłodowska-curie-actions-award-25758","The degree of social acceptance of the disabled sportsmen in Europe. Comparative analysis of the Paraolympics media coverage in the written press of Germany, England, Spain, Greece and France","UNIVERSITé MONTPELLIER 1","During the last years a growing interest is observed in E.U in promoting inclusion of people with disabilities in the mass media. 2003 was declared as European Year of People with Disabilities, and one of the major outcome of this event was the European Declaration on Media & Disability which on article 23 emphasizes the need to improve disability portrayal and inclusion of disabled people in media. Several studies have shown that sport helps disabled people to disengage from the common social r",{"id":1077,"funder":7,"programme":8,"title":1078,"piName":10,"institution":591,"country":20,"year":13,"amount":10,"abstract":1079},"cordis-marie-skłodowska-curie-actions-award-22153","Oxasilacyclohexenes -Chiral Scaffolds in Ruthenium Catalysed Tandem Synthesis","Oxasilacyclohexenes are synthetic intermediates with untapped potential; they combine the tuneable reactivity of substituted vinylsilanes with that of cyclic conformational rigidity. This proposal details the ruthenium catalysed formation of chiral oxasila cycle intermediates with pendant functionality capable of tandem reactions under residual Ru(II) Lewis acidic conditions. The first section focuses on the development of a research programme to optimise reactivity and selectivity in the synthe",{"id":1081,"funder":7,"programme":8,"title":1082,"piName":10,"institution":1083,"country":33,"year":13,"amount":10,"abstract":1084},"cordis-marie-skłodowska-curie-actions-award-21863","Quantitative structure activity relationships using novel linguistic and steric descriptors","PHARMACEUTICAL INSTITUTE, RHEINISCHE FRIEDRICH -WILHELMS-UNIVERSITÄT BONN","In 1996 during my one-year long stay to Japan I have proposed to apply Czech academic software GUHA to QSAR. Our Czech Japanese team used fingerprint descriptors for characterisation of important structural parts of molecules, processed by GUHA. In fact, our approach rests in phenomenological description as an alternative to molecular modelling. GUHA automatically generates hypotheses from empirical data and is several orders of magnitude faster, more productive and cheaper than classical modell",{"id":1086,"funder":7,"programme":8,"title":1087,"piName":10,"institution":1088,"country":33,"year":13,"amount":10,"abstract":1089},"cordis-marie-skłodowska-curie-actions-award-21420","Time-resolved thermodynamic parameters in donor-acceptor super-molecules and in photo-switches, analysed by laser-induced opto-acoustic spectroscopy","MAX-PLANCK SOCIETY REPRESENTED BY THE MAX-PLANCK INSTITUTE FOR BIOINORGANIC CHEMISTRY","Photoexcitation of biomimetic molecules, e.g., undergoing an electron transfer (ET) reaction or an isomerization, leads to optically well characterized intermediates. However, the phototransformation thermodynamic parameters, e.g., the enthalpy and entropy changes are not readily obtained. Laser-induced optoacoustic spectroscopy (LIOAS) is a suitable technique to study time-resolved thermodynamic profiles of photoreactions and has been successfully applied to molecular systems and biological pho",{"id":1091,"funder":7,"programme":8,"title":1092,"piName":10,"institution":1093,"country":179,"year":13,"amount":10,"abstract":1094},"cordis-marie-skłodowska-curie-actions-award-23591","Bose-Einstein Condensate of Heteronuclear molecules - creation and spectroscopy of Li-Sr BEC","INSTITUT F??R QUANTENOPTIK UND QUANTENINFORMATION DER ??STERREICHISCHEN AKADEMIE DER WISSENSCHAFTEN","We propose to achieve the creation of a two-species molecular Bose Einstein condensate, consisting of fermionic Li and Sr. The project will be conducted in the Ultracold group at the university of Innsbruck, under the supervision of Prof. Rudi Grimm.The molecular system is a promising candidate for the study of new physics with ultracold heteronuclear molecules. Especially interesting is their Bose condensation, since the high mass ratio, as well as their dipolar properties, allows manipulation ",{"id":1096,"funder":7,"programme":8,"title":1097,"piName":10,"institution":1098,"country":27,"year":13,"amount":10,"abstract":1099},"cordis-marie-skłodowska-curie-actions-award-22366","Computational models of Computer Narrative","UNIVERSIDAD COMPLUTENSE DE MADRID","This project aims to bring together two existing efforts in modelling the automated generation of stories, that used in ProtoPropp, developed in Madrid using AI techniques, and that used in MEXICA, developed in Mexico based on the Engagement-Reflection cycle, a psychological theory of how humans compose stories. The integration of the two different approaches should lead to a richer computational model of story generation. A fellowship is requested for Dr. Rafael Pérez y Pérez, developer of MEXI",{"id":1101,"funder":7,"programme":8,"title":1102,"piName":10,"institution":1103,"country":78,"year":13,"amount":10,"abstract":1104},"cordis-marie-skłodowska-curie-actions-award-23775","Mechanisms and Evolutionary Consequences of Wolbachia Dependent Oogenesis","UNIVERSITé CLAUDE BENARD LYON1","Symbiosis is an important factor in evolution as a source of evolutionary novelty and ecological diversity. Microbial symbionts in particular have had a large impact on the evolution of eukaryotic organisms. An intimate type of symbiosis is endosymbiosis, in which (typically) bacteria live within the host cells.Mitochondria and chloroplasts are examples of ancient endosymbioses that dramatically extended the range of eukaryotic life. Besides on these organelles of bacterial origin, many organism",200,{"programme":8,"total":1107,"withPiName":1108,"firstYear":1109,"lastYear":1110,"countryCount":1111,"perYear":1112,"topInstitutions":1188,"topCountries":1264},26094,19,1988,2027,53,[1113,1115,1118,1121,1123,1126,1129,1132,1135,1138,1141,1144,1147,1150,1153,1156,1159,1162,1165,1168,1171,1174,1177,1180,1183,1186],{"year":1109,"count":1114},1,{"year":1116,"count":1117},2003,74,{"year":1119,"count":1120},2004,586,{"year":13,"count":1122},868,{"year":1124,"count":1125},2006,641,{"year":1127,"count":1128},2007,553,{"year":1130,"count":1131},2008,591,{"year":1133,"count":1134},2009,712,{"year":1136,"count":1137},2010,787,{"year":1139,"count":1140},2011,838,{"year":1142,"count":1143},2012,901,{"year":1145,"count":1146},2013,1005,{"year":1148,"count":1149},2014,1009,{"year":1151,"count":1152},2015,1232,{"year":1154,"count":1155},2016,1231,{"year":1157,"count":1158},2017,1209,{"year":1160,"count":1161},2018,1353,{"year":1163,"count":1164},2019,1340,{"year":1166,"count":1167},2020,1314,{"year":1169,"count":1170},2021,1688,{"year":1172,"count":1173},2022,1362,{"year":1175,"count":1176},2023,1495,{"year":1178,"count":1179},2024,1522,{"year":1181,"count":1182},2025,1781,{"year":1184,"count":1185},2026,1532,{"year":1110,"count":1187},396,[1189,1192,1195,1198,1201,1204,1207,1210,1213,1216,1219,1222,1225,1228,1231,1234,1237,1240,1243,1246,1249,1252,1255,1258,1261],{"name":1190,"count":1191},"Centre National de la Recherche Scientifique CNRS",790,{"name":1193,"count":1194},"The Chancellor Masters and Scholars of the University of Cambridge",636,{"name":1196,"count":1197},"Kobenhavns Universitet",614,{"name":1199,"count":1200},"Chancellor, Masters and Scholars of the University of Oxford",579,{"name":1202,"count":1203},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",484,{"name":1205,"count":1206},"Imperial College of Science Technology and Medicine",428,{"name":1208,"count":1209},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",383,{"name":1211,"count":1212},"University of London",347,{"name":1214,"count":1215},"Katholieke Universiteit Leuven",280,{"name":1217,"count":1218},"The University of Birmingham",247,{"name":1220,"count":1221},"Eidgenoessische Technische Hochschule Zuerich",224,{"name":1223,"count":1224},"Aarhus Universitet",220,{"name":1226,"count":1227},"Universita Ca' Foscari  Venezia",219,{"name":1229,"count":1230},"University of Bristol",213,{"name":1232,"count":1233},"Ecole Polytechnique Federale de Lausanne",182,{"name":1235,"count":1236},"The University of Edinburgh",181,{"name":1238,"count":1239},"Universita Degli Studi di Padova",177,{"name":1241,"count":1242},"Universitat Wien",175,{"name":1244,"count":1245},"University of Leeds",169,{"name":1247,"count":1248},"Universiteit van Amsterdam",159,{"name":1250,"count":1251},"Universitetet I Oslo",156,{"name":1253,"count":1254},"Universiteit Utrecht",152,{"name":1256,"count":1257},"Technische Universiteit Delft",142,{"name":1259,"count":1260},"University of Warwick",141,{"name":1262,"count":1263},"Institut National de la Sante Et de la Recherche Medicale",139,[1265,1267,1269,1271,1273,1275,1277,1279,1281,1283,1285,1287,1289,1292,1295,1297,1299,1301,1303,1306,1308,1311,1314,1317,1320],{"name":20,"count":1266},5982,{"name":78,"count":1268},2854,{"name":27,"count":1270},2844,{"name":33,"count":1272},2362,{"name":55,"count":1274},2058,{"name":220,"count":1276},1624,{"name":61,"count":1278},1173,{"name":259,"count":1280},1075,{"name":539,"count":1282},996,{"name":12,"count":1284},788,{"name":179,"count":1286},634,{"name":494,"count":1288},608,{"name":1290,"count":1291},"NO",487,{"name":1293,"count":1294},"PT",482,{"name":412,"count":1296},313,{"name":712,"count":1298},277,{"name":598,"count":1300},256,{"name":752,"count":1302},168,{"name":1304,"count":1305},"TR",147,{"name":288,"count":1307},137,{"name":1309,"count":1310},"SI",113,{"name":1312,"count":1313},"CY",99,{"name":1315,"count":1316},"HU",97,{"name":1318,"count":1319},"LU",59,{"name":1321,"count":1322},"LT",56]