[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2008":3,"awarded-stats-msca-postdoctoral-fellowship":994},{"awarded":4,"total":993},[5,16,23,30,37,44,51,58,65,71,77,83,90,97,103,110,117,122,128,134,141,147,154,159,166,172,179,185,191,197,202,208,214,221,226,231,237,244,249,255,261,266,272,278,284,290,296,302,309,316,323,329,335,341,347,353,359,365,371,377,383,388,392,397,402,407,412,417,421,426,430,437,442,447,451,456,461,466,471,475,479,483,487,491,496,500,504,509,514,519,523,527,531,536,541,546,550,554,560,564,568,572,576,581,585,589,593,597,601,606,610,614,619,623,627,631,635,640,644,648,652,657,661,666,670,674,679,684,688,692,696,702,706,710,714,718,723,727,731,735,739,744,748,752,756,760,764,768,772,776,780,784,788,792,796,800,804,808,812,816,820,824,828,832,836,840,846,850,856,860,864,869,873,877,881,885,889,893,898,903,907,911,915,919,924,929,934,938,942,946,950,954,959,963,967,971,976,981,985,989],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-marie-skłodowska-curie-actions-award-40081","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","Research approaches to the human-centred Environment and Biomimetic design for spacecraft and terrestrial architecture",null,"SPACE SYNAPSE LTD.","IE",2008,"€221,515","This initiative will enable a leading American Space Architect and author of multiple NASA Disclosures of Invention and New Technology innovation documents to travel to, and work with the leading University in Ireland and a cutting-edge space-meets-humanities SME participating in the European Space Agency Incubator Initiative and having close links with leading European space scientists and astronauts.The incoming fellow will work with Space Synapse Ltd. on the implementation of an ESA-supported",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-marie-skłodowska-curie-actions-award-980043","Nanomist for fire suppression and explosion mitigation","UNIVERSITY OF SCIENCE AND TECHNOLOGY CHINA (USTC)","CN","€22,700","NanoMist is the trade name for the proprietary process technology of producing, scaling, transporting, and delivering nano- to micron-sized droplets, particles and mists. These technologies can be used to produce ultra fine water mist systems for fire suppression and explosion control and serve as an environmental friendly replacement of Halon 1301.The proposal aims to carry out numerical investigations of the dynamic two-way interaction of ultra fine water mist droplets with flames in the conte",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":26,"country":27,"year":13,"amount":28,"abstract":29},"cordis-marie-skłodowska-curie-actions-award-980014","Mesoporous Photocatalysts for the Degradation of Persistent Organic Pollutants","ALIGARH MUSLIM UNIVERSITY","IN","€35,609","This proposal is for an IIF award to enable a researcher from India to visit a laboratory in the UK. The researcher wishes to develop: (i) new scientific skills; (ii) a lasting collaboration within the UK; and (iii) potential to increase the research capacity of his home research environment.The proposal aims at understanding chemical mechanisms and catalyst design factors that influence photocatalysed degradation of selected pesticides in aqueous solution. This understanding will be used to des",{"id":31,"funder":7,"programme":8,"title":32,"piName":10,"institution":33,"country":34,"year":13,"amount":35,"abstract":36},"cordis-marie-skłodowska-curie-actions-award-39326","The microeconomics of growth across regions in Europe","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE","UK","€212,771","This project is going to enrich the empirics of regional convergence across Europe (Corrado et al 2005; Canova, 2004) which has mainly focussed on country or regional (NUTS2) aggregate growth performance. A new dataset at a smaller geographical scale (NUTS3) for 1031 European regions has been released in September 2005. This is a key element to test for the determinants of growth at the micro-level (Burgess and Venables, 2004) and to examine two of the most important aspects of growth performanc",{"id":38,"funder":7,"programme":8,"title":39,"piName":10,"institution":40,"country":41,"year":13,"amount":42,"abstract":43},"cordis-marie-skłodowska-curie-actions-award-40369","Dualities between gauge theory and string theory","UPPSALA UNIVERSITY","SE","€254,157","The project aims to give the researcher (Smedbäck) a strong research experience at the outgoing host (Princeton University), which is then to be applied in the return host (Uppsala University).The main research objective of the project 'Dualities between gauge theory and string theory' is to work on extensions of the AdS\u002FCFT duality. This is a manifestation of the so-called holographic duality, which occurs in string theory, which is the leading framework for uniting the physical description of ",{"id":45,"funder":7,"programme":8,"title":46,"piName":10,"institution":47,"country":48,"year":13,"amount":49,"abstract":50},"cordis-marie-skłodowska-curie-actions-award-40743","Invariant measures for stochastic differential equations driven by Levy processes and applications","RHEINISCHE FRIEDRICHS-WILHELMS-UNIVERSIT??????A?T BONN","DE","€250,364","We study existence, uniqueness, and regularity of invariant measures for stochastic differential equations in finite and infinite dimensional spaces driven by Levy-type noises.The main application is a solvability theory for nonlinear integro-differential partial differential equations in Sobolev spaces with respect to the invariant measure of suitable jump diffusion. In particular, the data are allowed to be singular and unbounded.",{"id":52,"funder":7,"programme":8,"title":53,"piName":10,"institution":54,"country":55,"year":13,"amount":56,"abstract":57},"cordis-marie-skłodowska-curie-actions-award-980062","Electron self trapping in supercritical CO2","HEAT PHYSICS DEPARTMENT OF UZBEKISTAN ACADEMY OF SCIENSES","UZ","€39,812","The development and utilization of new technologies using supercritical carbon dioxide (sc-CO2) makes them quite attractive their using in new nano-electronic devices and understanding of novel mechanisms for drug transfer in human organism. The main purpose of this proposal is the theoretical study molecular complex formation in sc-CO2 solutions induced by their interaction with low energy electrons, that leads to weak electron localization. As a main tool for the theoretical treatment of these",{"id":59,"funder":7,"programme":8,"title":60,"piName":10,"institution":61,"country":62,"year":13,"amount":63,"abstract":64},"cordis-marie-skłodowska-curie-actions-award-41851","Identification and analysis of candidate genes involved in key steps of gametophytic apomixis","UNIVERSITÄT ZURICH","CH","€173,831","Apomixis is a fascinating developmental process with a tremendous potential for plant breeding. Sexual reproduction and apomixis are closely interrelated and often occur within the same plant species. At least three key developmental steps are altered in a pomictic plants: (i) meiotic reduction is omitted or altered (apomeiosis), (ii) embryogenesis is initiated autonomously (parthenogenesis), and (iii) functional endosperm is formed through developmental adaptations. The molecular basis of (a) s",{"id":66,"funder":7,"programme":8,"title":67,"piName":10,"institution":68,"country":48,"year":13,"amount":69,"abstract":70},"cordis-marie-skłodowska-curie-actions-award-41375","Asymmetric cell division of Arabidopsis Zygote","EBERHARD-KARLS-UNIVERSITAET TUEBINGEN","€148,021","Asymmetric cell division generates two daughter cells that adopt different developmental fates and often differ in size. For example, a stem cell generates another stem cell and a daughter cell that gives rise to differentiated cells. This vital type of cell division occurs in a wide range of organisms, from bacteria and yeasts to plants and animals, and plays crucial roles during multicellular development. Molecular mechanisms of asymmetric cell division have been studied in animal model system",{"id":72,"funder":7,"programme":8,"title":73,"piName":10,"institution":74,"country":48,"year":13,"amount":75,"abstract":76},"cordis-marie-skłodowska-curie-actions-award-39868","Characterization of the genetic basis of Atopic Dermatitis","CHARITE UNIVERSITäTSMEDIZIN BERLIN","€158,197","Atopic Dermatitis (AD, also known as eczema) is a chronic inflammatory skin disease affecting 10-20% of children in western societies. AD is a complex disease arising from the interaction between genetic and environmental factors.Various genome-wide linkage scans have been undertaken to search for AD susceptibility genes with potential sites identified at various chromosomal locations. However, very little is known about AD causatives genes.The aim of this project will be the identification of t",{"id":78,"funder":7,"programme":8,"title":79,"piName":10,"institution":80,"country":27,"year":13,"amount":81,"abstract":82},"cordis-marie-skłodowska-curie-actions-award-980040","Physics Prospects at ALICEat LHC","UNIVERSITY OF JAMMU","€36,237","The ALICE experiment is a highly complex project involving about 1000 physicists from around the world. Both India and the United Kingdom are involved in it. The aim of the project is to study the properties of the Quark-Gluon Plasma (QGP), anew form of matter, which exists at extremely high energy densities. In ALICE these will be achieved through high temperatures, up to one million times hotter than the centre of the sun. The main purpose of my work at Birmingham would be dedicated to physics",{"id":84,"funder":7,"programme":8,"title":85,"piName":10,"institution":86,"country":87,"year":13,"amount":88,"abstract":89},"cordis-marie-skłodowska-curie-actions-award-41542","Regulation of aquaporins in maize roots in response to water stress","UNIVERSITE CATHOLIQUE DE LOUVAIN","BE","€152,185","Diminished crop water consumption is important to reduce the need for irrigation especially within areas where resources of clean water are scarce. Therefore, expert scientists with strong expertise in plant water relations is needed to address this new agricultural challenge. Aquaporins (AQPs) are channel proteins present in almost all living organisms that facilitate the rapid and passive transport of water across cell membranes.Whereas general features of AQP molecular structure have been des",{"id":91,"funder":7,"programme":8,"title":92,"piName":10,"institution":93,"country":94,"year":13,"amount":95,"abstract":96},"cordis-marie-skłodowska-curie-actions-award-42145","Subversion of the host cell by Shigella flexneri: the role of the type III secretion substrates OspB and OspC1","INSTITUT PASTEUR","FR","€158,548","Many gram-negative bacterial pathogens, including the intracellular human pathogen Shigella flexneri, use a dedicated secretion system, termed type III secretion (TTS) system, to inject bacterial proteins directly from the bacterium, across the host plasma membrane, into the host cell cytosol. The translocated bacterial effectors facilitate infection and virulence by manipulating host signalling pathways, including those regulating apoptosis, cytoskeletal rearrangements and cytokine production. ",{"id":98,"funder":7,"programme":8,"title":99,"piName":10,"institution":100,"country":34,"year":13,"amount":101,"abstract":102},"cordis-marie-skłodowska-curie-actions-award-39695","Control of neurogenesis in vertebrate brain","KING'S COLLEGE LONDON","€167,664","Cell diversity may arise at the moment of cell division when the cytoplasmatic determinants or membrane properties are asymmetrically distributed to the daughter cells. The asymmetric cell divisions rely therefore on the co-ordination of cell fate determinant localisation with the mitotic cleavage plan.This proposal will test the novel hypothesis that components of the vertebrate Planar Cell Polarity (PCP) pathway play critical roles in the control of progenitor divisions and neuronal fate deter",{"id":104,"funder":7,"programme":8,"title":105,"piName":10,"institution":106,"country":107,"year":13,"amount":108,"abstract":109},"cordis-marie-skłodowska-curie-actions-award-41020","Establishment and maintenance of cell polarity and tissue architecture in the lateral-line system of the zebrafish","CENTRE DE REGULACIÓ GENÒMICA","ES","€146,366","The establishment and maintenance of cellular polarity are critical for organ function. In addition to the ubiquitous apicobasal axis, many epithelial cells display a second polarity axis within the plane of the tissue, referred to as planar cell polarity. The orientation of hair-cell stereocilia in the inner ear represents a striking example of planar polarity in vertebrates. Although many of the proteins involved in the interpretation of the polarising cues have been identified, the mechanisti",{"id":111,"funder":7,"programme":8,"title":112,"piName":10,"institution":113,"country":114,"year":13,"amount":115,"abstract":116},"cordis-marie-skłodowska-curie-actions-award-980022","Application of photochromic compounds to improve resolution in fluorescence microscopy up to molecular scale","UNIVERSIDAD DE BUENOS AIRES","AR","€58,800","New techniques in far-field fluorescence microscopy have improved optical resolution down to several times the diffraction limit. The resolution currently achieved with these techniques is 28nm. Recently it was proposed that fluorescent reversible molecular compounds (photoswitches) could be utilized in fluorescence microscopy, allowing, in principle, to improve the resolution up to molecular dimensions, i.e. 1-5nm. The use of these photochromic compounds should enable the utilization of very lo",{"id":118,"funder":7,"programme":8,"title":119,"piName":10,"institution":40,"country":41,"year":13,"amount":120,"abstract":121},"cordis-marie-skłodowska-curie-actions-award-41185","Tracing the evolution of alpha-proteaobacterial genomes","€166,488","The microbial world remains largely unexplored. The goal of this project is to study microbial genome diversity and understand how the genomes of microbial pathogens evolve, using the alpha-proteobacteria as a model system. The alpha-proteobacteria are a bacterial subdivision of much interest from both a medical and an ecological standpoint. Many species establish chronic host-infections, with higher vertebrates (e.g. human, cattle and rodents) as well as with plants and insects. Well-known alph",{"id":123,"funder":7,"programme":8,"title":124,"piName":10,"institution":125,"country":62,"year":13,"amount":126,"abstract":127},"cordis-marie-skłodowska-curie-actions-award-40312","Self-assembly in autonomous Robotic Systems","ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE","€173,832","It has been observed that discrete and autonomous entities, on scales from the molecular to the planetary, bind to each other without being externally directed. The underlying process, termed self-assembly, encouraged researchers from many disciplines to study the design of modular and collective robot systems in which new entities arise autonomously by self-assembling. However, potential uses of such entities and their merits with respect to traditional robots are vastly unexplored. This projec",{"id":129,"funder":7,"programme":8,"title":130,"piName":10,"institution":131,"country":34,"year":13,"amount":132,"abstract":133},"cordis-marie-skłodowska-curie-actions-award-41488","The function of stereotyped calls of killer whales: a comparative approach","THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS","€222,409","Killer whales rely extensively on sound for communication and orientation, and some populations have developed complex repertoires of calls that are transmitted between individuals through vocal learning The ability to modify sounds through learning and experience is rare among mammals and complex vocal learning skills have thus far only been documented in humans, bats, pinnipeds, and cetaceans.Our knowledge about the precise function of killer whale vocal communication, as well as its intended ",{"id":135,"funder":7,"programme":8,"title":136,"piName":10,"institution":137,"country":138,"year":13,"amount":139,"abstract":140},"cordis-marie-skłodowska-curie-actions-award-980037","Development of novel non-destructive techniques to analyse food quality","KYRGYZ-TURKISH MANAS UNIVERSITY","KG","€55,000","Most analytical techniques used in quality control require isolation of the food component of interest. The original properties of the product are, therefore, destroyed during sample preparation and analysis. Oftentimes, such analyses are expensive, time consuming, and require sophisticated instrumentation, and hence are not suited for on-line quality control of food products. For on-line sensors, many physical principles have been checked, yet very few sensors having a meaningful correlation wi",{"id":142,"funder":7,"programme":8,"title":143,"piName":10,"institution":144,"country":27,"year":13,"amount":145,"abstract":146},"cordis-marie-skłodowska-curie-actions-award-980071","Conservation and evolutionary genetics of avian malaria with reference to South Pacific Islands","WILDLIFE INSTITUTE OF INDIA","€22,062","Our ultimate goal in proposed study is to model the degree to which malaria and other diseases have invaded the southern Pacific Islands and an assessment of future risk to the remote Melanesian avifauna based on host colonization histories and current genetic diversity. Lack of epidemiological surveys makes it difficult to understand the wider distribution of the parasites and how it has been transmitted among islands. Members of the silvereye complex (Zosterops lateralis) provide a unique oppo",{"id":148,"funder":7,"programme":8,"title":149,"piName":10,"institution":150,"country":151,"year":13,"amount":152,"abstract":153},"cordis-marie-skłodowska-curie-actions-award-42027","Oxidative stress in endothelial cells","UTRECHT UNIVERSITY","NL","€156,625","Reactive oxygen species (ROS) have been recently qualified as intracellular second messengers essential to many growth factors signalling. However, excess of ROS production by the newly discovered integral membrane NADPH oxidases (NOXs) results in or accompanies a large spectrum of life-threatening human diseases including cancer, diabetes, vascular diseases, neurodegeneration and aging. Although NOXs are the main ROS producing enzyme in vascular cells where they are involved angiogenesis and in",{"id":155,"funder":7,"programme":8,"title":112,"piName":10,"institution":156,"country":48,"year":13,"amount":157,"abstract":158},"cordis-marie-skłodowska-curie-actions-award-8902","MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.","€150,856","New techniques in far-field fluorescence microscopy have improved optical resolution down to several times the diffraction limit. The resolution currently achieved with these techniques is 28 nm. Recently it was proposed that fluorescent reversible molecular compounds ('photoswitches') could be utilized in fluorescence microscopy, allowing, in principle, to improve the resolution up to molecular dimensions, i.e. 1-5 nm. The use of these photochromic compounds should enable the utilization of ver",{"id":160,"funder":7,"programme":8,"title":161,"piName":10,"institution":162,"country":163,"year":13,"amount":164,"abstract":165},"cordis-marie-skłodowska-curie-actions-award-39807","Reliable communication under topology uncertainty","TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY","IL","€260,985","In 4G mobile networks it is envisaged that mobile users will be able to roam seamlessly between various networks and associated technologies, having access to a plethora of information driven applications requiring high data rates.Due to mobility, the wireless devices are expected to operate under arbitrary network topologies and channel conditions. The need to continuously update the terminals about the topology and channel conditions poses severe design and performance limitations.While the is",{"id":167,"funder":7,"programme":8,"title":168,"piName":10,"institution":169,"country":34,"year":13,"amount":170,"abstract":171},"cordis-marie-skłodowska-curie-actions-award-40900","Trophic interactions in marine plankton: copepod responses to a diatom defence strategy","PLYMOUTH MARINE LABORATORY","€168,798","A laboratory study is proposed to gain new insights into the trophic interactions between certain unicellular marine algae, the diatoms, and their main predators, calanoid copepods. Some diatoms produce polyunsaturated aldehydes (PUA) when wounded, which interfere with the reproduction of copepods and thus represent a defence strategy of the algae. This relationship may significantly shape the planktonic food web, but so far experiments have considered only few copepod species.In addition, most ",{"id":173,"funder":7,"programme":8,"title":174,"piName":10,"institution":175,"country":176,"year":13,"amount":177,"abstract":178},"cordis-marie-skłodowska-curie-actions-award-39600","Novel devices for optical light conversion based on high contrast refractive index waveguides","POLITECHNIKA WARSZAWSKA (WARSAW UNIVERSITY OF TECHNOLOGY)","PL","€184,005","This three years project is concerned with the development of a series of novel optical sources (nanowires) based on nonlinear optical conversion.The proposed research will allow the university team members from INRS-EMT and Warsaw University of Technology, in collaboration with their industrial partners and with the support of the University of Sherbrooke (also located in Quebec), to lead the international efforts in searching for low-cost, high performance all-optical sources.In order to compl",{"id":180,"funder":7,"programme":8,"title":181,"piName":10,"institution":182,"country":20,"year":13,"amount":183,"abstract":184},"cordis-marie-skłodowska-curie-actions-award-980017","Probing the long-term forcing mechanisms of the Asian Monsoon by magnetic analysis of aeolian dust in sediments from the North Pacific Ocean","INSTITUTE FOR GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES","€45,000","Understanding past climate change is crucially dependent on understanding oceanic and atmospheric circulation. The atmospheric circulation, which might provide meaningful information about the long-term forcing mechanisms of major atmospheric components, such as the monsoons, is poorly constrained. Aeolian dust preserved in deep-sea sediments provides an excellent means of determining past variations in continental paleoclimate and atmospheric circulation. In the main phase of this project, we w",{"id":186,"funder":7,"programme":8,"title":187,"piName":10,"institution":188,"country":151,"year":13,"amount":189,"abstract":190},"cordis-marie-skłodowska-curie-actions-award-41896","Bioavailability of trace metals in anaerobic granular sludge reactors","UNESCO-IHE INSTITUTE FOR WATER EDUCATION","€157,192","Research objectives and contentThe effects of the metals Co and Ni on the treatment performance of a continuously operated methanogenic UASB reactor fed with methanol as the substrate will be investigated. The contracted research fellow will carry out a work program to characterize the bioavailable metal fractions in methanogenic granular sludge from an UASB reactor treating a wastewater containing a mixture of heavy metals. Dissolved Ni and Co in the sludge will be discriminated into labile and",{"id":192,"funder":7,"programme":8,"title":193,"piName":10,"institution":194,"country":34,"year":13,"amount":195,"abstract":196},"cordis-marie-skłodowska-curie-actions-award-41886","The linguistic and cognitive processing of space in signed and spoken language","UNIVERSITY COLLEGE LONDON","€151,675","The project investigates the relationship between linguistic and non-linguistic cognitive processes in a comparison of spoken and signed language. Because signed and spoken languages differ with respect to the use of iconicity (i.e. visually motivated forms), comparison between language modalities can provide valuable insight into the nature of the interface between different cognitive processes. Specifically, the project focuses on the dimensions of size, shape, and location and seeks to explor",{"id":198,"funder":7,"programme":8,"title":199,"piName":10,"institution":200,"country":41,"year":13,"amount":120,"abstract":201},"cordis-marie-skłodowska-curie-actions-award-39237","Genetic control of cell diversification into neuronal subtypes","KAROLINSKA INSTITUTET","Vertebrate development is orchestrated by the coordinated deployment of multiple and diverse programs of cell commitment and differentiation. One of the fundamental questions in this process is how a discrete number of transcriptional programs and extracellular cues combine to produce the enormous cellular complexity that characterizes vertebrate organisms. This research aims at uncovering the general principles of how cellular diversity is created in the sensory nervous system.We aim to determi",{"id":203,"funder":7,"programme":8,"title":204,"piName":10,"institution":205,"country":34,"year":13,"amount":206,"abstract":207},"cordis-marie-skłodowska-curie-actions-award-40712","Role of the Wnt\u002Fb-catenin pathway in the dorso-ventral organisation of the telencephalon","KING 'S COLLEGE LONDON","€169,365","The complexity of the forebrain makes it a challenging task to elucidate how this structure forms during embryonic development. We are beginning to understand how a simple ectodermal sheet gives rise to the functional forebrain. Its most intricate structure is the telencephalon-derived cortex.A crucial step in forming the cortex is the establishment of distinct dorso-ventral (DV) cell identities. This process is regulated by Hedgehog (Hh) signalling as its abrogation prevents formation of ventra",{"id":209,"funder":7,"programme":8,"title":210,"piName":10,"institution":211,"country":27,"year":13,"amount":212,"abstract":213},"cordis-marie-skłodowska-curie-actions-award-980030","Novel metal clusters in protein clefts","INDIAN INSTITUTE OF TECHNOLOGY KANPUR","€89,100","The assembly, structure, and properties of novel iron and other metal nano-clusters in the cleft of the protein bacterial transferring will be investigated. The work is of high significance for understanding iron uptake by pathogenic bacteria and the mechanisms of bio-mineralization. Small protein-bound oxo iron clusters are of potential importance in the design of novel materials with unusual magnetic and catalytic properties, and of novel antibiotics. This bioinorganic chemistry project will b",{"id":215,"funder":7,"programme":8,"title":216,"piName":10,"institution":217,"country":218,"year":13,"amount":219,"abstract":220},"cordis-marie-skłodowska-curie-actions-award-980031","Assessment of community structure and seston quality effects on plankton carbon fluxes at two contrasting coastal sites","UNIVERSIDAD DE LA REPÚBLICA","UY","€70,675","This proposal focuses on investigating carbon fluxes whithin coastal pelagic ecosystems under the hypothesis that fluxes can be modulated by both community structure and seston quality. The study considers estimation of selected carbon fluxes, mesurement of seston chemical composition, and determination of planktonic community structure at seasonal and sub-seasonal scales in two contrasting coastal sites: the Gullmarsfjord (Sweden, Incoming Phase of the project) and the Río de la Plata (Uruguay,",{"id":222,"funder":7,"programme":8,"title":223,"piName":10,"institution":40,"country":41,"year":13,"amount":224,"abstract":225},"cordis-marie-skłodowska-curie-actions-award-41193","Canine genomics and the evolution of phenotypic diversity","€159,151","Rapid generation of morphological change has long puzzled biologists, as it is difficult to reconcile with the low frequency at which point mutations occur. In general, the mechanisms that underline the genesis of extreme diversity are unknown, but they ma y be relevant to many situations in the natural world (i.e. adaptive radiations). Here I propose the dog as a model for the study of such mechanisms: they have an extreme morphological diversity; their ancestor, the wolf, is still extant and a",{"id":227,"funder":7,"programme":8,"title":228,"piName":10,"institution":229,"country":34,"year":13,"amount":170,"abstract":230},"cordis-marie-skłodowska-curie-actions-award-40494","Genetic and epigenetic consequences of hybridization and polyploidy in Dactylorhiza (Orchidaceae)","ROYAL BOTANIC GARDENS, KEW","Hybridization and polyploidization are now recognized as major phenomena in the evolution of plants, promoting genetic diversity, adaptive radiation and speciation. New findings suggest that the interactions of the combined genomes in allopolyploids induce waves of genetic and epigenetic alterations that have the potential to result in novel expression patterns and new phenotypes.Such novelties, in combination with heterosis and gene redundancy, might confer on hybrids an elevated evolutionary p",{"id":232,"funder":7,"programme":8,"title":233,"piName":10,"institution":234,"country":34,"year":13,"amount":235,"abstract":236},"cordis-marie-skłodowska-curie-actions-award-40337","Optimisation of a non-antibody based technology to improve the efficiency of genome-wide analysis of DNA binding sites","UNIVERSITY OF GLASGOW","€158,479","Development of genome wide tools to study regulatory elements is particularly important to understand how gene expression is controlled in the human genome. The rational study of transcription factors and DNA-binding proteins in sequenced human genome is critical for making the genome sequences maximally useful.Chromatin Immuno-Precipitation (ChIP) materials analysed on microarrays for specific interactions (ChIP-chip) is a rapidly emerging technology in the study of DNA binding regulation prote",{"id":238,"funder":7,"programme":8,"title":239,"piName":10,"institution":240,"country":241,"year":13,"amount":242,"abstract":243},"cordis-marie-skłodowska-curie-actions-award-980055","Cell penetrating peptides: Modelling trans-membrane insertion","INSTITUTE OF PHYSICS OF THE NATIONAL ACADEMY OF SCIENCE OF UKRAINE","UA","€24,500","The lipid bi-layers of biological membranes are not permeable for hydrophilic molecules under physiological conditions. However, numerous biomedical applications, such as drug delivery and gene therapy, rely on reliable way of the transmembrane translocation of proteins, fragments of DNA and other water-soluble compounds. Thus, the search for possible transduction agents continued for several decades. Cell-penetrating peptides (CPPs) are recognized to be amino acid sequences, which make an effec",{"id":245,"funder":7,"programme":8,"title":246,"piName":10,"institution":100,"country":34,"year":13,"amount":247,"abstract":248},"cordis-marie-skłodowska-curie-actions-award-39425","The zona limitans intrathalamica as an organiser of diencephalic development","€159,613","The generation of the vertebrate brain relies on regionalisation of the neural plate through formation of boundaries. An important function of boundaries is to maintain the position of special groups of cells that are able to direct development of the neighbouring tissue. Such cell types form organisers and exert their action through secretion of long range signalling molecules. The formation of boundaries and their role in development of a forebrain region, the diencephalon, is still poorly und",{"id":250,"funder":7,"programme":8,"title":251,"piName":10,"institution":252,"country":114,"year":13,"amount":253,"abstract":254},"cordis-marie-skłodowska-curie-actions-award-980073","Looking for the Neural Basis of Human Consciousness through levels of awareness","CENTRO DE PSICOLOGIA MEDICA SAN MARTIN DE TOURS S.R.L.","€20,000","In recent years there has been an explosion of scientific work on consciousness, in cognitive neuroscience, psychology, and other fields. Only a few research groups have addressed questions related to awareness on subjects in different states of consciousness such as sleep, sedation or comatose state. Several studies showed partially preserved cognitive functions in pathologies of consciousness but presently there is no validated objective consciousness meter that can be used as proof or disproo",{"id":256,"funder":7,"programme":8,"title":257,"piName":10,"institution":258,"country":34,"year":13,"amount":259,"abstract":260},"cordis-marie-skłodowska-curie-actions-award-39125","Phylogenetic analysis of spatial and temporal patterns of community biodiversity","THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD","€80,374","The major goal of the present project is to develop innovative statistical methods for analysing community biodiversity, a highly timely objective within the current efforts for preventing biodiversity loss. Most of current biodiversity studies exclusively focus on the number of species and\u002For the relative abundance of the species in communities. Recent research has been undertaken to measure biodiversity by considering functional or phylogenetic information. However very few studies combine the",{"id":262,"funder":7,"programme":8,"title":263,"piName":10,"institution":264,"country":34,"year":13,"amount":265,"abstract":254},"cordis-marie-skłodowska-curie-actions-award-40629","Looking for the neural basis of human consciousness through levels of awareness","MEDICAL RESEARCH COUNCIL","€170,500",{"id":267,"funder":7,"programme":8,"title":268,"piName":10,"institution":269,"country":94,"year":13,"amount":270,"abstract":271},"cordis-marie-skłodowska-curie-actions-award-39389","Multidrug-resistant and hypervirulent tuberculosis: integral approach to rapid detection and evolution","INSTITUT PASTEUR DE GUADELOUPE","€103,304","Multidrug-resistant (MDR) and hyper-virulent (HV) Mycobacterium tuberculosis (MTB) strains increasingly circulate worldwide and start to threat European and global health security. Rapid detection of these hazardous MTB variants presents the first step in fighting TB and is vital for both patient and community health. We propose a novel integral approach to tackle modern TB. We propose to develop a three-step strategy based on use of sensitive molecular techniques and including simultaneous (1) ",{"id":273,"funder":7,"programme":8,"title":274,"piName":10,"institution":275,"country":48,"year":13,"amount":276,"abstract":277},"cordis-marie-skłodowska-curie-actions-award-40222","Electronic structure of nanosystems: Density Functional Theory approach","FREIE UNIVERSITAET BERLIN","€207,851","One of the core concepts in nanoscience and nanotechnology is the bottom-up approach, taking electrons, atoms, or molecules as the building blocks from which to create man-made nanosystems with the specific and desired electronic, biological, material, mechanical, or environmental properties. This approach however, poses a new and fundamental scientific challenge: the mastering of the way in which electrons, atoms, or molecules interact which each other, governed by the non-intuitive laws of qua",{"id":279,"funder":7,"programme":8,"title":280,"piName":10,"institution":281,"country":114,"year":13,"amount":282,"abstract":283},"cordis-marie-skłodowska-curie-actions-award-980059","Global regulation of lipid biosynthesis in Gram-positive bacteria: structural and biochemical characterization of FapR","INSTITUTO DE BIOLOGÍA MOLECULAR Y CELULAR DE ROSARIO","€22,963","FapR is a transcription factor that negatively controls the expression of several genes of the fatty acid and phospholipid biosynthesis in Bacillus subtilis. It is the first global regulator of lipid synthesis discovered in bacteria and is largely conserved in Gram positive organisms. A key intermediate in fatty acid biosynthesis, malonyl-CoA, acts as a negative effector of the transcriptional repressor FapR.   We propose to use structural biology, genetic and biophysical approaches to study the",{"id":285,"funder":7,"programme":8,"title":286,"piName":10,"institution":287,"country":20,"year":13,"amount":288,"abstract":289},"cordis-marie-skłodowska-curie-actions-award-980045","Dissection of the metabolic grid of IAOx, a precursor for natural plant products and the plant hormone auxin","NORTHEAST AGRICULTURAL UNIVERSITY","€49,501","Cruciferous plants, which include the economically important Brassica vegetables and the model plant Arabidopsis, produce indole glucosinolates and indole alkaloids. These bioactive natural products are known to confer specific pest resistance to crucifer plants. For humans, the compounds are known as flavour compounds, cancer-preventive compounds, and biopesticides. Indole-3-acetaldoxime (IAOx) is an intermediate in biosynthesis of indole glucosinolates and indole alkaloids, and is a precursor ",{"id":291,"funder":7,"programme":8,"title":292,"piName":10,"institution":293,"country":27,"year":13,"amount":294,"abstract":295},"cordis-marie-skłodowska-curie-actions-award-980018","Radiolarian artificial neural network based estimation of the paleo sea surface temperatures and salinities in the Arctic and Antarctic Ocean and their response to insolation forcing","NATIONAL INSTITUTE OF OCEANOGRAPHY","€36,000","The modern Boreal summer corresponds to Antarctic winter season and vice versa, while their summer and winter are separated by 6 months due to anti-phase bipolar seesaw in the solar insolation. Similarly, Boreal (65oN) and Austral (65oS) summer insolations suggest an anti-phase relationship, implying warmer Arctic corresponding to cooler Antarctic in the geological past. Sea surface temperature (SST) estimates for the 18000 years BP last glacial maximum (LGM) are suggested to be underestimated b",{"id":297,"funder":7,"programme":8,"title":298,"piName":10,"institution":299,"country":27,"year":13,"amount":300,"abstract":301},"cordis-marie-skłodowska-curie-actions-award-980032","Noble metal nano-structures - Preparation using soft templates, characterisation and applications","JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH","€20,340","The present project is aimed at imparting thorough training to the candidate in nanomaterials synthesis, characterisation and applications. We have recently adopted an innovative approach for the synthesis of noble metal nano structures having high catalytic activity for selective hydrogenation reactions using swollen mesophases of anionic surfactants as 'soft templates'. Two patents have been obtained for the works related to this. In the present project bi-metallic nano structures of Pt and Pd",{"id":303,"funder":7,"programme":8,"title":304,"piName":10,"institution":305,"country":306,"year":13,"amount":307,"abstract":308},"cordis-marie-skłodowska-curie-actions-award-40604","The role of histone variant macroH2A in Epigenetics","FOUNDATION FOR BIOMEDICAL RESEARCH OF THE ACADEMY OF ATHENS","EL","€176,938","The histone variant macroH2A1 (mH2A1) is associated with gene repression but the molecular mechanisms by which it exerts its function are largely unknown. mH2A is recruited to the IL-8 promoter by ATF-2 where it functions as a transcriptional repressor. Interestingly, macroH2A1 has been shown to bind O-acetyl-ADP-ribose (OAADPR).The functional consequences of this interaction are unknown. This proposal will take two distinct approaches to elucidate the function of mH2A1 in the cell. First, this ",{"id":310,"funder":7,"programme":8,"title":311,"piName":10,"institution":312,"country":313,"year":13,"amount":314,"abstract":315},"cordis-marie-skłodowska-curie-actions-award-41374","Improving water treatment processes through chalk recrystallisation","UNIVERSITY OF COPENHAGEN","DK","€182,403","Calcite (CaCO3) plays a role in many public and industrial regimes that are critical for the health and economic well-being of society, but in many cases, a lack of understanding of the fundamental physical and chemical properties controlling calcite growth and dissolution translates to direct problems or to inefficiency in water treatment processes.A common method for removing toxic trace-metal contamination during water treatment is to add lime (Ca(OH)2 or CaO). Trace metals are trapped in gro",{"id":317,"funder":7,"programme":8,"title":318,"piName":10,"institution":319,"country":320,"year":13,"amount":321,"abstract":322},"cordis-marie-skłodowska-curie-actions-award-980038","Computational modelling and design of responsive industrial fluids","MOSCOW STATE UNIVERSITY, FACULTY OF PHYSICS","RU","€62,700","Depending on thermodynamic conditions, amphiphilic molecules may self-assemble into wormlike micelles. Entanglements between wormlike micelles create network structures, which impart high viscosity and elasticity to the fluid. This wide range of rheologic al properties, combined with the sensitivity to thermodynamic conditions, makes these fluids perfectly suited for environmentally friendly applications in oilfield industries. By mixing the viscoelastic surfactants (VES) with polymers, the rheo",{"id":324,"funder":7,"programme":8,"title":325,"piName":10,"institution":326,"country":41,"year":13,"amount":327,"abstract":328},"cordis-marie-skłodowska-curie-actions-award-40877","Next generation turbulent multiphase CFD modelling for the electrochemical process industries","KUNGL TEKNISKA HöGSKOLAN","€270,062","The chlorate process and the chlor-alkali process are just two examples of widely-used industrial processes in which electrochemical reactions, occurring at the surfaces of electrodes immersed in baths of liquid electrolyte, give rise to gas bubble evolution, which in turn leads to the turbulent flow of the electrolyte. The operation of such cells and reactors is far from optimal, leading in most cases to excessive energy consumption and environmental pollution. Optimization of such complex syst",{"id":330,"funder":7,"programme":8,"title":331,"piName":10,"institution":332,"country":107,"year":13,"amount":333,"abstract":334},"cordis-marie-skłodowska-curie-actions-award-42169","Rapid Climate variability in response to changing glacial and orbital boundary conditions during the Mid-Pleistocene transition","UNIVERSITAT DE BARCELONA","€144,665","One of the key developments in palaeoclimatology has been the discovery of recurrent and rapid climate changes in the past, illustrating that natural climate variability may also occur on the submillennial time-scales of relevance to humanity. Rapid climate events are widely believed to have involved, if not have been largely derived from changes in the oceans' large-scale circulation and have been associated by several workers with fundamental shifts in the Atlantic meridional overturning circu",{"id":336,"funder":7,"programme":8,"title":337,"piName":10,"institution":338,"country":48,"year":13,"amount":339,"abstract":340},"cordis-marie-skłodowska-curie-actions-award-40299","Right to an Open Future?: An Ethnographic study of parents and professionals experiences of the diagnostic and predictive genetic testing of children in the Era of Genomics","UNIVERSITY OF HAMBURG","€154,795","This project will be an in-depth qualitative study of the practice and social consequences of the diagnostic and predictive genetic testing of children, focusing specifically on the experiences of parents and health professionals.The study will be based a t the Research Centre for Biotechnology, Society and the Environment (BIOGUM) at the University of Hamburg and carried out by Dr. Jacquelyne Luce in cooperation with children's hospitals, clinics and genetic research centres in a multicultural ",{"id":342,"funder":7,"programme":8,"title":343,"piName":10,"institution":344,"country":320,"year":13,"amount":345,"abstract":346},"cordis-marie-skłodowska-curie-actions-award-980028","Micro-Analysis of Acculturation among Russian Immigrants and Emigrants","MOSCOW STATE UNIVERSITY OF TECHNOLOGY STANKIN","€59,600","There is almost no research devoted to emigrants in Russia and few studies about Russians abroad. Recent changes in the Russian society and the globalization make acculturation important in science and public discourse in Russia. The proposed project, which consists of three studies, examines acculturation of exchange students and sojourners in Moscow and of Russian immigrants in the Netherlands, Germany, the United Kingdom and the U.S.A. The study elaborates on the PhD study carried out by Irin",{"id":348,"funder":7,"programme":8,"title":349,"piName":10,"institution":350,"country":94,"year":13,"amount":351,"abstract":352},"cordis-marie-skłodowska-curie-actions-award-39688","Landscape-scale Carbon cycle Analysis using hyperspectral remotely Sensed data Of plant and ecosystem functionAl diveRsity","UNIVERSITÉ JOSEPH FOURIER GRENOBLE I","€134,682","The applicant's objective is to learn and develop new methods, especially hyperspectral remote sensing, for integrating plant functional diversity changes into landscape-scale carbon cycle models. Climate and land-use changes affect patterns of plant functional diversity, which in turns are strong drivers of the carbon cycle. Plant functional diversity allows to consider carbon cycle-related processes operating on large time and spatial scales - from local and transient ecosystem response to lon",{"id":354,"funder":7,"programme":8,"title":355,"piName":10,"institution":356,"country":34,"year":13,"amount":357,"abstract":358},"cordis-marie-skłodowska-curie-actions-award-39798","Multidisciplinary approaches to biodiversity analysis: testing evolutionary hypotheses in south-east Asian freshwater taxa","UNIVERSITY OF WALES BANGOR","€161,314","The origins of biodiversity have intrigued evolutionary biologists since the earliest times, and have resulted in a plethora of theories to explain these origins. To date, there has been a tendency to use distribution patterns of biota to confirm preferred hypotheses (a field known broadly as historical biogeography), instead of a genuine attempt to test between competing hypotheses.A recently emerging field utilises the ease with which DNA sequences can be read to provide more objective testing",{"id":360,"funder":7,"programme":8,"title":361,"piName":10,"institution":362,"country":34,"year":13,"amount":363,"abstract":364},"cordis-marie-skłodowska-curie-actions-award-39431","Bacterial dynamics and abundance; quantitative coupling of hydrocarbon degradation and specific bacterial communities","UNIVERSITY OF NEWCASTLE UPON TYNE","€229,327","Industrial development has led to exponential increase in fossil fuel consumption. This has caused serious damage to environment and needs proper management. An understanding of the relationship between hydrocarbon pollution and microbial diversity will be useful for developing predictive and effective models for biological treatment of polluted environments. New molecular tools that provide a clear picture of the relative abundance and dynamics of microorganisms in natural habitats are now in u",{"id":366,"funder":7,"programme":8,"title":367,"piName":10,"institution":368,"country":34,"year":13,"amount":369,"abstract":370},"cordis-marie-skłodowska-curie-actions-award-39569","The role of thermal Physics in determining the masses of stars","CARDIFF UNIVERSITY","€161,995","The evolution of a star forming molecular cloud depends critically on the thermodynamic processes, which determine the temperature, and hence the pressure, of the gas, i.e. heating, cooling, chemistry and radiation transport. These processes play a key role in determining the overall efficiency of star formation, the stellar initial mass function, the patterns of clustering, the binary statistics, the masses and lifetimes of accretion discs, and the external appearance of star forming clouds.The",{"id":372,"funder":7,"programme":8,"title":373,"piName":10,"institution":374,"country":107,"year":13,"amount":375,"abstract":376},"cordis-marie-skłodowska-curie-actions-award-40298","Star formation in the central regions of active galaxies and data mining in radioastronomy at sub-millimetre wavelengths","CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS-INSTITUTO DE ASTROFÍSICA DE ANDALUCÍA -","€234,162","The objectives of this proposal can be summarised as follows:Scientific aim:The proposed project is focused on the onset of nuclear activity in the absence of interactions. The dense and warm molecular gas plays a key role in this process, and its morphology, kinematics and physical properties will be traced by means of (sub)millimeter data using the first interferometer working at submillimeter wavelengths, the Submillimeter Array (SMA).This study will allow selecting the best candidates to be ",{"id":378,"funder":7,"programme":8,"title":379,"piName":10,"institution":380,"country":320,"year":13,"amount":381,"abstract":382},"cordis-marie-skłodowska-curie-actions-award-980035","Dictatorship, Hierarchy, and the Stalinist Economy: the Soviet Defence Industry 1929 -1953","ROSSIISKAYA EKONOMICHESKAYA SHOKOLA (ENGLISH NAME - NEW ECONOMIC SCHOOL)","€27,413","The project will investigate the forces shaping the working arrangements of Stalin's dictatorship in the Soviet economy, using the detailed documentation now available in the Russian state and economic archives as its evidence base. Its ultimate motivation is to understand how a dictator chose to rule subject to the resources available and other constraints that limited his choices, and the influences on his choices that arose from within his own regime. The working arrangements of Stalin's regi",{"id":384,"funder":7,"programme":8,"title":385,"piName":10,"institution":386,"country":34,"year":13,"amount":10,"abstract":387},"cordis-marie-skłodowska-curie-actions-award-220104","COccolithophores Morphology, BIogeography, geNetic and Ecology database","NATURAL HISTORY MUSEUM","Coccolithophores are unicellular calcifying algae that form a major component of the oceanic phytoplankton. They play a key role in the global carbon cycle as a pump of  inorganic carbon to the deep ocean and to the sediment, and are responsible for a considerable part of the ocean\u002Fatmosphere exchange of climate relevant gases (CO2, DMS). In the context of global climate change, and especially ocean acidification, understanding the role of  plankton in modulating oceanic biogeochemistry has beco",{"id":389,"funder":7,"programme":8,"title":390,"piName":10,"institution":194,"country":10,"year":13,"amount":10,"abstract":391},"cordis-marie-skłodowska-curie-actions-award-221592","The genetic basis of an exaggerated sexual ornament in the stalk-eyed fly Teleopsis dalmanni","Stalk-eyed flies have eyes displaced laterally from the head on elongate stalks in both sexes. Males have exaggerated eyespan and this trait functions as a sexual ornament.  Evidence from the field and laboratory shows that females prefer to mate with males that have the largest eyespan. It is thought that male eyespan acts as a signal of male genetic quality, as this sexually exaggerated trait exhibits heightened condition dependent expression. Teleopsis dalmanni is emerging as one of the key m",{"id":393,"funder":7,"programme":8,"title":394,"piName":10,"institution":395,"country":62,"year":13,"amount":10,"abstract":396},"cordis-marie-skłodowska-curie-actions-award-220274","Topological and functional modularity in biological regulatory networks","University of Zurich","Most functions and structures in living organisms seem to depend on subsets of elements organized as modules. In a modular system a certain process, performed by a module, does not depend heavily on the elements outside the module, and hence it is semi-autonomous. Modularity promotes evolvability, an organism’s capacity to generate heritable phenotypic variation, because it permits adjustment of a module without perturbing other functions and allows the combination of previously evolved function",{"id":398,"funder":7,"programme":8,"title":399,"piName":10,"institution":400,"country":34,"year":13,"amount":10,"abstract":401},"cordis-marie-skłodowska-curie-actions-award-219612","Next Generation Wireless Broadband Access Systems and Advanced Coding Techniques","RINICOM LIMITED","The scientific and technological objectives of this SME-driven industry-academia multi-disciplinary proposal for Intra-European Fellowship (termed Wi-CODING) are to provide the means for transfer of knowledge from the Host organisation to the Fellow with the aim of “strengthening a leading independent position in education or enterprise” in the future endeavors of the Fellow. The project aims to implement this plan within the context of R&D efforts aimed at making significant advances in key tec",{"id":403,"funder":7,"programme":8,"title":404,"piName":10,"institution":405,"country":94,"year":13,"amount":10,"abstract":406},"cordis-marie-skłodowska-curie-actions-award-219611","Functional connectivity of developing hippocampal networks: characterization of “circuit-hubs”","UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II","Oscillatory activity synchronized over a large population of neurons is the signature of the developing brain and play a major role in the construction of neuronal circuits. The hypothesis at the basis of our research proposal is that the initiation of synchronous network events is dependent on precise connectivity patterns of the neuronal network. Models of complex systems and networks offer solid tools to characterize mathematically the dynamics of neural circuits and predict the existence of ",{"id":408,"funder":7,"programme":8,"title":409,"piName":10,"institution":410,"country":48,"year":13,"amount":10,"abstract":411},"cordis-marie-skłodowska-curie-actions-award-219224","Interference effects in inner-shell excitation of diatomic molecules studied by polarization analysis of fluorescence from valence-ionized states","UNIVERSITAET KASSEL","In the present project the degree of linear polarization of fluorescence in molecular ions populated via the Auger decay of Raman regime resonantly excited inner-shells of the NO and CO molecules will be studied theoretically and experimentally for the first time. In the NO molecule we will focus on the Auger decay of the N*O and NO* resonances into the A state of the NO+ ion investigating the intensities and the degree of polarization of the individual NO+(A - X) fluorescence bands appears in t",{"id":413,"funder":7,"programme":8,"title":414,"piName":10,"institution":415,"country":94,"year":13,"amount":10,"abstract":416},"cordis-marie-skłodowska-curie-actions-award-221574","Smoothness of the invariant Hilbert scheme of affine spherical varieties for the existence of wonderful varieties","UNIVERSITE JOSEPH FOURIER GRENOBLE 1","Let G be a reductive linear algebraic group over the complex numbers. A G-variety, an algebraic variety with an algebraic action of the group G, is said to be spherical if it is normal and has an open orbit for a maximal connected solvable subgroup of G. We aim to complete the classification of spherical varieties by proving Luna's conjecture on a special class of spherical varieties, called wonderful. To a wonderful variety one can naturally associate an invariant combinatorial object in terms ",{"id":418,"funder":7,"programme":8,"title":419,"piName":10,"institution":415,"country":94,"year":13,"amount":10,"abstract":420},"cordis-marie-skłodowska-curie-actions-award-219785","Complex Projective Contact Manifolds","In our project we are interested in the classification of complex projective contact Fano manifolds and of quaternion-Kahler manifolds with positive scalar curvature. Also we want to classify smooth  subvarieties of projective space whose dual is also smooth. We divide these problems into the following four objectives:   1) to expand the dictionary between the differential geometric properties of quaternion-Kahler manifolds with positive scalar curvature and algebro-geometric properties of compl",{"id":422,"funder":7,"programme":8,"title":423,"piName":10,"institution":424,"country":94,"year":13,"amount":10,"abstract":425},"cordis-marie-skłodowska-curie-actions-award-219195","Introspective journey and change: is adult development possible?","INSTITUT EUROPEEN D ADMINISTRATION DES AFFAIRES","For all of the time, effort, and money invested in attempts to help individuals develop through education, training and coaching, there are few studies that really assess the real impact of the change process. Reasons for this paucity are lack of convenience and practicality of longitudinal designs to study demonstrable results at the individual level. Additionally, the intricacies of adult development may cast a shadow over the understanding of the individual change process, for example, the “h",{"id":427,"funder":7,"programme":8,"title":428,"piName":10,"institution":264,"country":34,"year":13,"amount":10,"abstract":429},"cordis-marie-skłodowska-curie-actions-award-220939","Control of cell shape in the peripodial membrane of the wing disc of Drosophila melanogaster","I propose to analyze how epithelial cell shape is controlled, using the Drosophila peripodial membrane as a model system. Drosophila third instar imaginal discs are a composed of two contiguous layers of cells of distinct morphology: a pseudostratified one, called the proper epithelium (PE), and a squamous epithelium, the peripodial membrane (PM). While the PE has been deeply studied, little is known about the PM. The peripodial membrane has the ability to change its shape in response to ecdyson",{"id":431,"funder":7,"programme":8,"title":432,"piName":10,"institution":433,"country":434,"year":13,"amount":435,"abstract":436},"cordis-marie-skłodowska-curie-actions-award-221783","Markov Chain Monte Carlo reconstruction of the large-scale structure with the Lyman alpha forest","SCUOLA NORMALE SUPERIORE","IT","€153,120","We address in this proposal the inverse problem for the reconstruction of the properties of the intergalactic medium based on the measured neutral hydrogen Lyman-α absorption observed in the spectra of high redshift quasars.  We suggest the application of ARGO, a Bayesian sampling solver that has been developed by the applicant during his PhD thesis for the reconstruction of the large-scale structure and its properties based on galaxy redshift-surveys. This will permit for the first time to have",{"id":438,"funder":7,"programme":8,"title":439,"piName":10,"institution":440,"country":41,"year":13,"amount":10,"abstract":441},"cordis-marie-skłodowska-curie-actions-award-220202","Compact Binaries as Gravitational-Wave Sources","MAX IV Laboratory, Lund University","We propose a research program to explore the implications of compact binaries, with emphasis on pulsar binaries, for gravitational-wave astronomy. Interest in compact binaries derives not only from an intrinsic motivation of understanding their origin and evolution in various astrophysical environments, but also from the fact that these are strong sources of gravitational waves. Pulsar binaries, one of the prime targets for ground-based gravitational-wave detectors, form a subgroup of compact bi",{"id":443,"funder":7,"programme":8,"title":444,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":446},"cordis-marie-skłodowska-curie-actions-award-220899","Black Holes, Superstrings, and Holography","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","This project aims to understand certain quantum aspects of black hole physics, in particular its entropy and the degrees of freedom associated with the horizon. The many states in which a black hole can exist can be understood through a hologram living in one dimension less than the black hole.  This idea of a hologram has proved to be very fruitful in recent work in string theory. Our work aims to extend these successes to situations where high curvature effects are important and can be systema",{"id":448,"funder":7,"programme":8,"title":449,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":450},"cordis-marie-skłodowska-curie-actions-award-220449","LISA and LISA Path Finder data-analysis","The Laser Interferometer Space Antenna (LISA) mission, due to be launched in ten years' time, will mark a key development in the field of gravitational-wave (GW) physics; whereas ground-based detectors, currently in operation, have a limited sensitivity and will achieve a major result if they can detect individual events, LISA will make  GW detection routine and will open the chapter of GW astronomy and cosmology. Many issues, both scientifical and technological, are still open, some of them wil",{"id":452,"funder":7,"programme":8,"title":453,"piName":10,"institution":454,"country":41,"year":13,"amount":10,"abstract":455},"cordis-marie-skłodowska-curie-actions-award-220048","Time-resolved diffusive X-ray scattering for the study of cell membrane transport","GOETEBORGS UNIVERSITET","In this application we propose to apply the emerging tools of solution-phase, time-resolved X-ray scattering to the study of transfer phenomena in membrane transport proteins. Diffusive X-ray scattering of heavy metals in solution has recently been used by the host to monitor reaction kinetics of simple photochemical systems on a picosecond timescale. We seek to extend the technique to monitor structural dynamics inside the transport channel of halorhodopsin (hR), an important membrane protein t",{"id":457,"funder":7,"programme":8,"title":458,"piName":10,"institution":459,"country":94,"year":13,"amount":10,"abstract":460},"cordis-marie-skłodowska-curie-actions-award-221205","The epistemology of biopolitics","Université Paris Diderot-Paris 7","The epistemology of biopolitics: rediscovering Georges Canguilhem  This research project will cast new light on the works of the philosopher of life and medical sciences, Georges Canguilhem. In the second half of the Twentieth Century a new and pressing issue emerged in international intellectual discourse: the ability of scientific rationality to intervene in the evolution of the human species. In the mid 1970’s, Michel Foucault defined this issue as “biopolitics”. Building upon the research of",{"id":462,"funder":7,"programme":8,"title":463,"piName":10,"institution":464,"country":87,"year":13,"amount":10,"abstract":465},"cordis-marie-skłodowska-curie-actions-award-221755","Neurophysiological correlates of the anatomically discrete organization of the auditory nerve","KATHOLIEKE UNIVERSITEIT LEUVEN","Although the auditory nerve (AN) is one of the best studied sensory nerves, a neurophysiological correlate of its discrete anatomical organization remains to be demonstrated. This project seeks to find physiological correlates of this type of organization by recording from large populations of AN fibers in single animals, focused at a particular cochlear region and examining their responses for a quantal organization. An approach with dense sampling of individual nerves and with auditory stimuli",{"id":467,"funder":7,"programme":8,"title":468,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":470},"cordis-marie-skłodowska-curie-actions-award-220620","Revising the Role of Groundwater in Life Cycle Assessment","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","Life Cycle Assessment (LCA) is the standardised method for assessing the environmental impacts of any product or service. After quantifying all associated emissions and the consumption of resources, this impact is expressed with respect to a few common impact categories. These are supposed to reflect major societal and environmental priorities. Although groundwater is the most extracted raw material in the world, and extraordinarily  important for most parts of the EU, it is virtually ignored in",{"id":472,"funder":7,"programme":8,"title":473,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":474},"cordis-marie-skłodowska-curie-actions-award-220247","Cellular factors and pathways in the entry of Bunyaviridae","Bunyaviridae are important pathogens in vertebrates and humans with over 350 members spread over many parts of the world. Many of them cause severe health problems and some are now classified as potential biological weapons in bioterrorism. Currently there are no available vaccines or treatments. Human activity and climate change are known factors favoring the emergence, reemergence, and rapid spread of virus diseases, including Bunyaviridae such as Hantavirus, a recent example that these viruse",{"id":476,"funder":7,"programme":8,"title":477,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":478},"cordis-marie-skłodowska-curie-actions-award-221054","Mass transfer of metals and sulfur between mafic silicate melts and volatiles: an interdisciplinary approach","A systematic experimental study will be conducted to obtain quantitative information on the distribution of Cu, Au and S between andesitic and basaltic silicate melts and volatile phases.   The experiments will be carried out in cold seal and internally heated pressure vessels, at various conditions characteristic of upper crustal magma reservoirs. The fluid phase will be trapped as synthetic fluid inclusions in mafic minerals or in fine grained mineral traps at the experimental run conditions. ",{"id":480,"funder":7,"programme":8,"title":481,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":482},"cordis-marie-skłodowska-curie-actions-award-220260","Constructing an Artificial Enzyme for Olefin Metathesis","The introduction of stable and selective catalysts for olefin metathesis (OM) has considerably simplified the construction of double bonds. Herein we propose to tackle two areas of the OM reaction that have received little attention. First, we will address selectivity problems in an important type of OM reaction: metathesis cross-coupling or simply cross metathesis (CM). Second, we will examine the potential applications of OM in chemical biology. OM has no biological counterpart and therefore i",{"id":484,"funder":7,"programme":8,"title":485,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":486},"cordis-marie-skłodowska-curie-actions-award-221637","A Systems Biology Approach to Elucidate the Yeast Metabolic Network","The ultimate goal of systems biology is to generate mathematical models to comprehensively describe the dynamics of a biological system. Among all biochemical and informational systems that operate in cells, metabolism is unique because the composition and topology of the network of metabolic reactions is almost completely known. What is currently poorly understood, is how this system operates, how it is controlled and how it adapts to changing conditions of supply and demand. Most current model",{"id":488,"funder":7,"programme":8,"title":489,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":490},"cordis-marie-skłodowska-curie-actions-award-219870","Dynamics and Structure of the Earth’s Mantle: a multidisciplinary approach","We propose a multidisciplinary approach involving mineral physics, geophysics and geodynamics to study the evolution and the current physical conditions of the Earth’s mantle. Starting from a mineral physics database, we will jointly invert long-period seismic waveforms and gravity data to infer 3-D thermal and compositional structure of the Earth’s mantle. The thermodynamic database used for the inversion will also provide the physical properties for time-dependent mantle convection computation",{"id":492,"funder":7,"programme":8,"title":493,"piName":10,"institution":494,"country":151,"year":13,"amount":10,"abstract":495},"cordis-marie-skłodowska-curie-actions-award-220752","Assessment Frameworks for Epistemic Games","UNIVERSITEIT UTRECHT","Contemporary video games are profoundly engaging and motivating to young people, and a growing body of research on epistemic games, or games based on professional practices shows that epistemic games that simulate professional training can make deep and powerful learning available to students. In epistemic games, players develop expertise by playing as novices training to be professionals such as engineers, urban planners, science journalists, and so on. In these games, however, players are not ",{"id":497,"funder":7,"programme":8,"title":498,"piName":10,"institution":464,"country":87,"year":13,"amount":10,"abstract":499},"cordis-marie-skłodowska-curie-actions-award-220002","Development of Self-lubricating Nanocomposite Coatings impregnated with in-situ formed MoS2 for Tribological Applications","Use of self-lubricated coatings in dynamic contacting parts of the system not only reduces complexity, weight, and cost to the system, but also improves the performance to a great extent by reducing friction and wear. Unlike liquid lubricants, the release of various toxic and harmful chemicals to the environment can also be avoided. So, a self-lubricated surface with a long lifetime is a promising one to meet future challenges. The most common solid lubricants are graphite and transition metals ",{"id":501,"funder":7,"programme":8,"title":502,"piName":10,"institution":494,"country":151,"year":13,"amount":10,"abstract":503},"cordis-marie-skłodowska-curie-actions-award-220500","Physical Observables in Quantum Gravity","In recent years a very good understanding of the kinematical structures provided by candidate theories of quantum gravity, such as Loop Quantum Gravity, Spin Foam Models and Causal Dynamical Triangulations, has been obtained. The next key step is to approach the dynamics of these theories, which is encoded in the physical, that is diffeomorphism invariant, observables of the theory. However, the construction of these quantities is extremely complicated, due to the non-linear structure of the the",{"id":505,"funder":7,"programme":8,"title":506,"piName":10,"institution":507,"country":313,"year":13,"amount":10,"abstract":508},"cordis-marie-skłodowska-curie-actions-award-220055","Effect of structure upon the reactivity of catalytic nanoparticles","DANMARKS TEKNISKE UNIVERSITET","Heterogeneous catalysis is an area where nanotechnology is present in people's everyday lives. Catalytic processes are found in diverse applications such as fuel-refining, the petrochemical industry, fertiliser production, automotive catalytic converters, biochemistry etc. They also provide a pathway to renewable, clean energy in the form of hydrogen fuel cell technology. Most modern catalysts take the form of catalytically active nanoparticles dispersed over some highly porous support medium. I",{"id":510,"funder":7,"programme":8,"title":511,"piName":10,"institution":512,"country":434,"year":13,"amount":10,"abstract":513},"cordis-marie-skłodowska-curie-actions-award-221065","Biodiversity and connectivity in the resilience of coastal marine communities","UNIVERSITA DEGLI STUDI DI GENOVA","Changes in diversity underpin the very nature and integrity of ecosystems, including how they function, deliver goods and services, and respond to disturbances. Yet understanding the underlying mechanisms of biodiversity change remains both one of the greatest challenges in ecological science and of fundamental importance to resource management and conservation. The key problem is the need to integrate the effects of different factors operating on different space and time scale on biodiversity. ",{"id":515,"funder":7,"programme":8,"title":516,"piName":10,"institution":517,"country":306,"year":13,"amount":10,"abstract":518},"cordis-marie-skłodowska-curie-actions-award-221173","Multiscale Modeling of Mechanical Properties of Metals and Interfaces","ARISTOTELIO PANEPISTIMIO THESSALONIKIS","This main objective for the Marie Curie International Incoming Fellowship is to expand and strengthen the research\u002Feducational activities of the Mechanics Laboratory at the Aristotelion University of Thessaloniki, (AUT), Greece, by forming a formal and long-term collaborative relationship with the W. M. Keck Computational Materials Theory Center (CMTC) at California State University Northridge (CSUN), an NSF-funded Center.  We propose to develop physical models, numerical algorithms and robust m",{"id":520,"funder":7,"programme":8,"title":521,"piName":10,"institution":464,"country":87,"year":13,"amount":10,"abstract":522},"cordis-marie-skłodowska-curie-actions-award-219943","Coronal Seismology and Magnetoseismology","The project aims to further our understanding of magnetohydrodynamical (MHD) waves in the solar corona and the upper layers of the solar interior and specifically addresses the coupling between the waves at the solar surface and in the corona. Within the local helioseismology community it is becoming widely accepted that magnetic fields should be taken into account when inverting the seismological data to infer local properties of the solar plasma. While the local helioseismic techniques have re",{"id":524,"funder":7,"programme":8,"title":525,"piName":10,"institution":234,"country":34,"year":13,"amount":10,"abstract":526},"cordis-marie-skłodowska-curie-actions-award-219671","Between Segregation and Social Integration: Recent Immigrants and Foreign Workers in the USA and in the UK","The central research objective of this project is to compare processes of, and opportunities for, social integration of immigrant communities in the United States and the United Kingdom. Case studies will be carried out in Seattle (WA) and Glasgow and Edinburgh (Scotland)  To summarize: the project will focus on the following 1. Political contexts of migration discourses and policies 2. Contexts of integration opportunities (social integration policies) 3. Local integration\u002Fsegregation contexts ",{"id":528,"funder":7,"programme":8,"title":529,"piName":10,"institution":234,"country":34,"year":13,"amount":10,"abstract":530},"cordis-marie-skłodowska-curie-actions-award-221624","Geometric Aspects of Integrable Nonlinear Systems","The issues of the research project are focused on the theory of integrable systems and its relation to the field theories. The first objective is further development of the theory of the integrability preserving dispersive deformations of integrable dispersionless systems. Next is the formulation of the classical R-matrix approach to the Frobenius manifolds. Another objective is the revision of the theory of Whitham hierarchies related to the moduli spaces of Riemann surfaces of all genera. The ",{"id":532,"funder":7,"programme":8,"title":533,"piName":10,"institution":534,"country":48,"year":13,"amount":10,"abstract":535},"cordis-marie-skłodowska-curie-actions-award-220775","Developement of robust and quantitative biosensors based on near-infrared two-dyed silicate nanoparticles","FRIEDRICH-SCHILLER-UNIVERSITÄT JENA","The aim of this project is to develop quantitative biological sensors based on fluorescent spherical silicate nanoparticles (amorphous silica, zeolite beta) in controlled sizes in the range of 50 to 200 nanometers in diameter. The quantification of the analyte is based on a ratiometric detection of fluorescence from two dyes. The dyes are chosen such that the fluorescence of one dye is a function of an analyte (ion, biomolecule) concentration (sensing dye) whereas the fluorescence of the other d",{"id":537,"funder":7,"programme":8,"title":538,"piName":10,"institution":539,"country":151,"year":13,"amount":10,"abstract":540},"cordis-marie-skłodowska-curie-actions-award-221048","A program for high throughput molecular diagnostics of the mutation negative syndromic and nonsyndromic craniosynostoses","STICHTING RADBOUD UNIVERSITEIT","Objectives:  To identify the genetic basis of FGFR and TWIST1 mutation negative syndromic and nonsyndromic craniosynostosis  Research Plan: Patient cells from the sutures of FGFR and TWIST1 mutation negative syndromic and nonsyndromic craniosynostosis will be screened for mutations using two genetic approaches.  Firstly genomic DNA from the patient cells will be hybridised to Affymetrix snp microarrays to determine copy number variation.  Secondly the transcriptome of cranial suture cells will b",{"id":542,"funder":7,"programme":8,"title":543,"piName":10,"institution":544,"country":48,"year":13,"amount":10,"abstract":545},"cordis-marie-skłodowska-curie-actions-award-221206","Red-Shifted Fluorescence Protein Tomography","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","The introduction of transgenes that express fluorescent proteins (FPs) into cells has revolutionized the ability to visualize many cellular and sub-cellular processes that are otherwise invisible with traditional means of optical imaging. Fluorescent proteins have been widely used in microscopic imaging, however deep tissue imaging has not been possible, before the recent development of fluorescent proteins emitting beyond the 600 nm absorption threshold.  In the present proposal the applicant w",{"id":547,"funder":7,"programme":8,"title":548,"piName":10,"institution":512,"country":434,"year":13,"amount":10,"abstract":549},"cordis-marie-skłodowska-curie-actions-award-220201","Nontrivial Vortex States and their Connection to the Transition to Turbulence","The applicant will study the existence of unstable nonlinear travelling wave solutions to the Navier-Stokes equations in isothermal ducts of square and rectangular cross-section where the basic flow is homogeneos in the streamwise direction. After this, more challenging situations will be considered with streamwise inhomogeneous base flows: boundary layer and backward facing step .   Discovering such states is crucial for the understanding of turbulence and for its control. Relating the solution",{"id":551,"funder":7,"programme":8,"title":552,"piName":10,"institution":534,"country":48,"year":13,"amount":10,"abstract":553},"cordis-marie-skłodowska-curie-actions-award-221100","Attosecond dynamics of ion-biomolecule collisions by nuclear and electron wavepackets","The advent of ultrashort pulses produced by free-electron lasers and high harmonic generation has opened up the way to a new chemistry at the femto and attosecond time scales. Processes such as laser induced ionisation and dissociation can now be monitored in real time and can be used to control chemical reactions. However, the dynamics of charge transfer (CT) processes taking place in a collision have never been investigated. ATTONEW aims at analyzing the mechanism of CT during an ion-biomolecu",{"id":555,"funder":7,"programme":8,"title":556,"piName":10,"institution":557,"country":558,"year":13,"amount":10,"abstract":559},"cordis-marie-skłodowska-curie-actions-award-221090","Spline-like function spaces with applications to scattered data approximations","UNIVERSITAT WIEN","AT","We will develop mathematical methods for scattered data approximation that can be used to implement efficient algorithms in signal processing and related areas. So far, the problem of reconstructing an unknown function from a given discrete set of sampling points has been studied in shift invariant spaces, i.e. spaces generated by translates of a function (or finitely many functions). We propose to consider the problem in spaces generated by translates of compressed copies of a function (or fini",{"id":561,"funder":7,"programme":8,"title":562,"piName":10,"institution":557,"country":558,"year":13,"amount":10,"abstract":563},"cordis-marie-skłodowska-curie-actions-award-220518","Identification of novel protein kinases required for meiosis","During meiosis, one round of DNA replication is followed by two rounds of cell division. This results in production of four haploid cells from a diploid precursor. Proteins required for this reduction of chromosome number are largely unknown. In this project, we want to identify novel proteins required for meiotic chromosome segregation. Protein kinases are the key cellular regulators and some of them are known to be essential for proper segregation of chromosomes during meiosis. We now want to ",{"id":565,"funder":7,"programme":8,"title":566,"piName":10,"institution":234,"country":34,"year":13,"amount":10,"abstract":567},"cordis-marie-skłodowska-curie-actions-award-220266","Time-frequency analysis of paraproducts","Singular integral operators form one of the most important classes of operators in Mathematical Analysis and its applications. Paraproducts are special operators from this class, which are at the same time the building blocks for general singular integral operators. These special singular integral operators are particularly useful in the study of certain partial differential equations . Similarly to multiplier operators like the classical Hilbert transform, they are characterized by the fact tha",{"id":569,"funder":7,"programme":8,"title":570,"piName":10,"institution":507,"country":313,"year":13,"amount":10,"abstract":571},"cordis-marie-skłodowska-curie-actions-award-219552","Optimal mating strategies in pelagic copepods: ecological and evolutionary meaning","The mechanisms that govern mating in marine pelagic copepods are still hardly known. Pelagic copepods exhibit two different mating systems; there are species that require only one mating to ensure female fertility, and others that need re-insemination. Several aspects related with mating ecology, such as male fitness, mate choice, mate-finding behaviour, mating behaviour, or predation risk associated with mating, seem to be theoretically different and related to the mating system. Copepod swimmi",{"id":573,"funder":7,"programme":8,"title":574,"piName":10,"institution":507,"country":313,"year":13,"amount":10,"abstract":575},"cordis-marie-skłodowska-curie-actions-award-221696","Appendicularian houses fate and role in carbon sedimentation  and nutrition of zooplankton","Little is currently known about the mechanisms by which zooplankton could find and locate sinking particles in the marine pelagic environment. However this process is believe to be an important pathway in reducing the downward carbon flux in the ocean and could also be an important food supply for zooplankton organisms or fishes larvae. In pelagic Ocean, appendicularians are important producers of large sinking particles through the continuous secretion of mucous filtering structures named “the ",{"id":577,"funder":7,"programme":8,"title":578,"piName":10,"institution":579,"country":94,"year":13,"amount":10,"abstract":580},"cordis-marie-skłodowska-curie-actions-award-221721","Reactive oxygen species production and reactive oxygen species mediated signalling","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","Oxygen plays the important role not only in respiration of the organisms. The interaction of oxygen molecules with cell components produces the reactive oxygen species (ROS). ROS is always present in biological cells and their concentration is maintained in continuous level under normal conditions. But the level of ROS increases significantly under stress conditions which may leads to the cells death. However besides the destructive processes in biological structures ROS do execute the role of s",{"id":582,"funder":7,"programme":8,"title":583,"piName":10,"institution":464,"country":87,"year":13,"amount":10,"abstract":584},"cordis-marie-skłodowska-curie-actions-award-221478","The development of a timely and robust tool to analyze relations that link crop and livestock diversity and income to nutrition in poor rural areas in Sub-Saharan Africa","Undernutrition is a worldwide problem. Advances in agricultural technologies have enormously increased food production worldwide, however, still 854 million of people remain chronically underfed. Addressing the links between agriculture and nutrition is crucial to translate agricultural successes into nutrition outcomes. The project will develop a practical and timely tool to carry out in-depth assessment studies of the relations that link crop and livestock diversity and income to nutrition in ",{"id":586,"funder":7,"programme":8,"title":587,"piName":10,"institution":464,"country":87,"year":13,"amount":10,"abstract":588},"cordis-marie-skłodowska-curie-actions-award-221709","Efficient Micromachining of Ceramic Materials in free formed, accurate and reliable shapes","Technical ceramics (Al2O3, ZrO2, SiC, Si3N4) have received increasing attention in the recent years and they significantly contribute to sustainable growth and development. However, their extensive use throughout industry is still hindered by the lack of efficient technologies enabling to provide accurate and free formed components without defects. Near\u002Fnet-shape manufacturing techniques have mayor benefits (mass production, different size available and versatile shapes). However, the accurate c",{"id":590,"funder":7,"programme":8,"title":591,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":592},"cordis-marie-skłodowska-curie-actions-award-219632","Single spin manipulation in locally oxidized p-type semiconductor heterostructures","Exploring the different relaxation mechanisms leading to spin decoherence and thus the realization of long spin lifetimes in single electron nanodevices is one of the central issues in nowadays spintronics. Although such effects have been widely studied in 2DEG-based nano-constrictions, the possibility of the utilization of stronger correlation phenomena characteristic to valence band holes on the transport properties of confined 2DHG systems has remained still unexplored. Recently it has become",{"id":594,"funder":7,"programme":8,"title":595,"piName":10,"institution":579,"country":94,"year":13,"amount":10,"abstract":596},"cordis-marie-skłodowska-curie-actions-award-219786","Bioremediation of toxic metals and radionuclides using naturally evolved bacteria capable of intra-cellular reduction without oxidative stress","Most toxic metals and radionuclides can be naturally rendered insoluble-immobile by bacterial reduction, which may be exploited for bioremediation purposes at waste repository sites. Some bacteria (e.g. iron or sulphate respirers) are receiving intense attention as their envelope-located electron transport chain can carry out such reductions. However, this process is subject to inhibition by nitrate and oxygen, usually present at waste sites. It also involves 1 e- transfer reactions generating r",{"id":598,"funder":7,"programme":8,"title":599,"piName":10,"institution":494,"country":151,"year":13,"amount":10,"abstract":600},"cordis-marie-skłodowska-curie-actions-award-219881","Climate variability and associated limnological changes in the coldest region of Eurasia over the past millennium: chironomid-based reconstructions in NE Siberia","Understanding the climatic instability on decadal to centennial timescales is essential for determining the baseline and recent trends of climatic variations. Our study has the aim to reconstruct climatic variability and climate impact on lakes over the last millennium in the Republic of Sakha (Yakutia), the coldest region of Eurasia. This goal will be achieved by means of chironomid analysis (Diptera: Chironomidae) of littoral and deep-water sediment records from three arctic lakes located in t",{"id":602,"funder":7,"programme":8,"title":603,"piName":10,"institution":604,"country":163,"year":13,"amount":10,"abstract":605},"cordis-marie-skłodowska-curie-actions-award-221092","Ring-walking, metal coordination and aryl-halide oxidative addition","WEIZMANN INSTITUTE OF SCIENCE","The proposed project deals with the formation of new late transition metal-based stilbene and stilbazole complexes, formed via a series of transformations, including metal-olefin coordination, metal ring-walking, and aryl-halide oxidative addition. This project is related to recently published results (van der Boom, M. E. et al J. Am. Chem. Soc. 2005, 127, 9322; Organometallics, 2006, 25, 3308; Organometallics, 2007, in press; Chem. & Eng. News 2005 Sept. 19,). Our studies indicate that a zerova",{"id":607,"funder":7,"programme":8,"title":608,"piName":10,"institution":469,"country":62,"year":13,"amount":10,"abstract":609},"cordis-marie-skłodowska-curie-actions-award-219222","Metabolomics of single eukaryotic cells","We propose to develop an analytical platform for single-cell metabolomics and apply it in fundamental studies carried out on a model eukaryotic organism, Saccharomyces cerevisiae. Due to the minute amounts of metabolites present in each cell, almost all current methods used in biochemistry and molecular biology provide data that are averaged over an entire cell population while even cells in monoclonal cultures display profound variations on all physiological levels. This approach to molecular b",{"id":611,"funder":7,"programme":8,"title":612,"piName":10,"institution":579,"country":94,"year":13,"amount":10,"abstract":613},"cordis-marie-skłodowska-curie-actions-award-221332","Parameter Optimisation of a terrestrial biosphere model to Link processes to Inter annual variability of Carbon fluxes in European forest Ecosystems","Inter annual variations of net ecosystem carbon exchange (NEE), driven by weather and climate, are known to contribute to variation in the annual growth rate of atmospheric CO2 globally, but little is known about the underlying processes in each region. Better ability to predict future atmospheric CO2 levels and climate change should thus be gained by understanding the current inter annual variation in the biotic response to environmental forcing. In this context, I propose to assess, using a st",{"id":615,"funder":7,"programme":8,"title":616,"piName":10,"institution":617,"country":94,"year":13,"amount":10,"abstract":618},"cordis-marie-skłodowska-curie-actions-award-221075","Dynamics of second messengers in axon guidance: decrypting the codes","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","The mature nervous system is an intricate network in which neurons are connected to specific partners. The construction of the network requires directed growth of axons towards their appropriate targets during development and during neuronal regeneration after a lesion. Axons must navigate through a complex environment where they are guided by a combination of attractive and repulsive molecules. Cellular second messengers, particularly calcium and cyclic nucleotides – cyclic adenosine monophosph",{"id":620,"funder":7,"programme":8,"title":621,"piName":10,"institution":617,"country":94,"year":13,"amount":10,"abstract":622},"cordis-marie-skłodowska-curie-actions-award-221834","Differential Involvement of Electrically Coupled Networks in Brain Oscillations","It is generally assumed that the brain generates behavior through the electrical activity of neurons. Information coding relies on coordinated activity of neuronal assemblies. This cooperative activity of central neurons is embodied in the oscillations and synchronization of neuronal activity among different frequencies bands. The mechanisms allowing the emergence of neuronal oscillations are variable and include fast synaptic transmission and electrical coupling between interneurons or principa",{"id":624,"funder":7,"programme":8,"title":625,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":626},"cordis-marie-skłodowska-curie-actions-award-220264","Ultracold Bose-Fermi Mixtures of Metastable Helium","Experiments using Bose-Einstein condensates (BEC) of ultracold atoms have demonstrated the quantum mechanical similarities between ultracold bosonic atoms and photons of light.  In addition, research using ultracold fermionic atoms has shed light on other interesting and\u002For unsolved phenomena, such as the pairing of electrons in superconductors and the mechanisms of high Tc superconductivity.  Helium has both stable bosonic (4He) and fermionic (3He) isotopes that may be cooled to quantum degener",{"id":628,"funder":7,"programme":8,"title":629,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":630},"cordis-marie-skłodowska-curie-actions-award-221453","Lipidomic Analysis and functional study of the lipid biosynthesis of the plastid of Apicomplexa parasites","Apicomplexa is a phylum of intracellular parasites, including pathogens of medical and veterinary importance. In contrast to pathogenic bacteria, these parasites are eukaryotes and share numerous metabolic pathways with their animal hosts, making therapeutic target development difficult. Two genera (Plasmodium and Toxoplasma), which are responsible for serious diseases in humans, have been the focus of most studies in this parasite group. Malaria caused by Plasmodium is one of the deadliest huma",{"id":632,"funder":7,"programme":8,"title":633,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":634},"cordis-marie-skłodowska-curie-actions-award-219346","Development of an unified energy wear approach to quantify the wear rate from nano to macro contact size range: Application to the Fretting Wear Problem","Wear induced by debris formation and ejection is becoming a critical problem in many industrial applications. Fretting wear associated to small oscillating sliding displacement is considered as a plague in many contacted systems submitted to vibrations loadings (aeronautics, energy, biotechnology, nanotechnologies etc …). Hence, there is a critical interest to formalize wear degradations and wear rates to predict the contact endurances. Unfortunately, the current formalisms (Archard's law etc …)",{"id":636,"funder":7,"programme":8,"title":637,"piName":10,"institution":638,"country":41,"year":13,"amount":10,"abstract":639},"cordis-marie-skłodowska-curie-actions-award-221121","Identity and biogeochemical role of chemoautotrophic prokaryotes in aquatic ecosystems","UPPSALA UNIVERSITET","We aim to identify relevant aquatic chemoautotrophic prokaryotes, which can play a key biogeochemical role with the capacity to fix CO2 independently of light. Although severely underestimated, chemoautotrophy can be widespread in natural systems and it can importantly participate in carbon cycling. Chemoautotrophs are highly diverse at the phylogenetical and metabolical levels, but our knowledge about both aspects is still very limited and will be assessed in this project. Firstly, we will iden",{"id":641,"funder":7,"programme":8,"title":642,"piName":10,"institution":638,"country":41,"year":13,"amount":10,"abstract":643},"cordis-marie-skłodowska-curie-actions-award-220714","Integrative taxonomy and the origin of species","Morphological, behavioural and molecular characters are of interest in evolutionary biology because they evidence lineage divergence and are contingent properties of species. With the incorporation of molecular biology into taxonomy, taxonomists realized that species diversity could not be completely deciphered using morphology alone. Nonetheless, the incorporation of multiple biological properties into taxonomic practice has been controversial. This proposal aims to test how the combined use of",{"id":645,"funder":7,"programme":8,"title":646,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":647},"cordis-marie-skłodowska-curie-actions-award-220299","Mediterranean Coral Calcification in response to global change","Global environmental change and the rise of CO2 have been identified as a major threat to scleractinian corals and coral reefs. General predictions are that ocean acidification will be detrimental to reef growth and that 40 to > 80 % of present-day reefs will decline during the next 50 years. While the impact of global change on reef-building corals has been intensely studied, not much is known on the response of deep-sea, cold-water corals or azooxanthellate shallow water corals. Also, the role",{"id":649,"funder":7,"programme":8,"title":650,"piName":10,"institution":617,"country":94,"year":13,"amount":10,"abstract":651},"cordis-marie-skłodowska-curie-actions-award-220784","Strategy of piliated meningococci to cross multicellular defense barriers","The main goal of this proposal is to determine how the deadly bacterial pathogen, Neisseria meningitidis (NM), crosses the blood-tissue barriers and invades the brain and other vital organs. The main hypothesis behind this project is that NM, by interacting with the vascular endothelial cells with its pili, induces a signal that opens cell-to-cell junctions and allows the bacteria to penetrate the natural barriers using the paracellular route rather than the transcellular one as currently accept",{"id":653,"funder":7,"programme":8,"title":654,"piName":10,"institution":655,"country":434,"year":13,"amount":10,"abstract":656},"cordis-marie-skłodowska-curie-actions-award-220790","Spectroscopy of ordered and quasi ordered complex solids","CONSIGLIO NAZIONALE DELLE RICERCHE","Complex oxides with competing interactions are one of the biggest challenges in condensed matter physics and at the same time promising materials for applications.  The recent developments in ARPES (angle-resolved photoemission spectroscopy) studies of cuprates opens a direct window on how strong correlations renormalize energy bands, and may provide important clues into the unusual properties of these materials.  The proposed research will combine the Guest's expertise in modeling complex oxide",{"id":658,"funder":7,"programme":8,"title":659,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":660},"cordis-marie-skłodowska-curie-actions-award-220157","System biology of nitrogen-carbon-signal integration in the overall Arabidopsis signaling network","Plant development is under the control of abiotic environment. Nitrogen (N) and Carbon (C) signaling are well known to interact together, but also with a set of diverse signaling pathways including light and the plant hormones, auxin or cytokinin. Relationships of C\u002FN “balance” with these “growth factors” are hypothesized to trigger the regulation of broad developmental processes such as root\u002Fshoot development or flowering.  The overall aim of this proposal is to use a genomics and systems biolo",{"id":662,"funder":7,"programme":8,"title":663,"piName":10,"institution":664,"country":94,"year":13,"amount":10,"abstract":665},"cordis-marie-skłodowska-curie-actions-award-219662","Influence of periodic climate changes on the evolution of mountain ranges","UNIVERSITE D'AIX MARSEILLE","Recent studies have highlighted complex linkages among erosion, tectonics and climate in active mountain belts. Although the exact nature of those interactions is still widely debated, clearly they have a crucial impact on the evolution of geologic systems. Furthermore, it is well known that Late Cenozoic climate oscillates between glacial and interglacial periods at time scales of 10-100 kyrs. Yet, the effects of climate variability at these frequencies are seldom considered in studies of the e",{"id":667,"funder":7,"programme":8,"title":668,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":669},"cordis-marie-skłodowska-curie-actions-award-220432","Unveiling galaxy assembly from next generation photometry","The primary goal of this project is to develop a new type of statistical approach to constrain the assembly of the evolving population of galaxies over cosmic time using modern multi-waveband photometric surveys. This work combines uniquely the expertise of: (1) the proposed fellow, in the development and application of state-of-the-art statistical techniques to interpret galaxy spectral energy distributions (SEDs); (2) the host scientist, in the development of sophisticated models to describe t",{"id":671,"funder":7,"programme":8,"title":672,"piName":10,"institution":655,"country":434,"year":13,"amount":10,"abstract":673},"cordis-marie-skłodowska-curie-actions-award-220511","Characterization of biomarkers in breath of lung and breast cancer patients","Recent studies have noted that dogs are able to identify with high confidence the presence of cancerous tissues in patients at an early stage based on sniffing a breath sample. Because exhaled breath provides non-invasively a continuous window to the biochemical activity within a person, its analysis for medical diagnosis has produced a substantial literature. However, its diagnostic reliability is still incomparable to that of dogs. In fact, breath analysis has not been introduced into common c",{"id":675,"funder":7,"programme":8,"title":676,"piName":10,"institution":677,"country":434,"year":13,"amount":10,"abstract":678},"cordis-marie-skłodowska-curie-actions-award-219363","Towards a European model of biomedical law?","EUROPEAN UNIVERSITY INSTITUTE","The EUROBIOLAW hypothesizes that the ill-known but developing body of EC law in the field of biomedical issues is of crucial importance, because it involves crucial legal and theoretical stakes that are worth studying. First, it serves as an emblem for the ongoing tension within the field of biomedical law in general between the “fundamental rights” approach and a wider approach that notably takes into account the ever-increasing economic and financial dimension of biotechnologies. In this respe",{"id":680,"funder":7,"programme":8,"title":681,"piName":10,"institution":682,"country":48,"year":13,"amount":10,"abstract":683},"cordis-marie-skłodowska-curie-actions-award-219273","Interface of Intelligent Control Philosophy and Mechatronics Technology for Tyre-Surface Interaction","TECHNISCHE UNIVERSITAET ILMENAU","The project covers the methodological and technological investigations on the controllability problems of the tyre friction, slip and rolling resistance with the aim to enhance the road safety and to reduce energy losses by vehicle driving. The research tooling will be created using the intelligent control methods, primarily on a basis of fuzzy logic, and promising mechatronics technique. The key objectives of the project are: - Development of the engineering applications of artificial intellige",{"id":685,"funder":7,"programme":8,"title":686,"piName":10,"institution":655,"country":434,"year":13,"amount":10,"abstract":687},"cordis-marie-skłodowska-curie-actions-award-221262","THz Optics for Biological In-situ Analitical Spectroscopy","This three years project is concerned with the development of a Near-field (NF) THz absorption spectroscopy system with specific reference to the real-time characterization of bio-matter. This system will exploit electromagnetic resonance fingerprints (i.e. characteristic spectral responses). µm and sub-µm resolution will enable to spatially discriminate important low-energy materials resonances in bio-samples.  The proposed research will allow the team members from INRS-EMT and CNR-INFM-SOFT, a",{"id":689,"funder":7,"programme":8,"title":690,"piName":10,"institution":638,"country":41,"year":13,"amount":10,"abstract":691},"cordis-marie-skłodowska-curie-actions-award-219885","Language contact in the eastern Mediterranean in the Late Middle Ages : Greek in a multilingual society","The project aims to investigate the extent of language contact in the eastern Mediterranean in the Late Middle Ages (13th – 17th c.).It focuses on Medieval Greek,which became a locus point of multilingualism,because of the socio-political environment,i.e. the contact between Greek- and Romance-speaking populations developed in large parts of eastern Mediterranean after the fall of Constantinople to the Franks (1204).Consequently,the main emphasis of the investigation will be placed on language c",{"id":693,"funder":7,"programme":8,"title":694,"piName":10,"institution":617,"country":94,"year":13,"amount":10,"abstract":695},"cordis-marie-skłodowska-curie-actions-award-221415","Implication of connexin 43 in chronic renal failure","Chronic renal failure (CRF), one of the main causes of disability in western societies, is promoted by a variety of factors including hypertension, diabetes, ischemic, immunological and toxic injury. These factors are linked by their common ability to promote chronic inflammation and fibrosis leading to decline of renal function. Dialysis and transplantation are the only available options that allow survival of patients. Arresting the progression of CRF is one of the major challenges of public h",{"id":697,"funder":7,"programme":8,"title":698,"piName":10,"institution":699,"country":700,"year":13,"amount":10,"abstract":701},"cordis-marie-skłodowska-curie-actions-award-220558","Statistical Tools for studying genetic architecture","UNIVERSITETET I OSLO","NO","Molecular biology has shown that most phenotypes are affected by complex, interacting gene networks. Yet, evolutionary biologists and population geneticists often assume very simple genetic architectures where genes act more of less independently of each other. These assumptions are made for conceptual clarity and are partially justified through statistical definitions of gene effects that capture the main effects of alleles as averages over many complex interactions. Still, recent research has ",{"id":703,"funder":7,"programme":8,"title":704,"piName":10,"institution":655,"country":434,"year":13,"amount":10,"abstract":705},"cordis-marie-skłodowska-curie-actions-award-219770","Hierarchical self-assembly of electroactive supramolecular systems on pRe-patterned surfaces: multifunctional architectures for organic FETs","HESPERUS aims at enabling cross-disciplinary training and research at the interface between Electrical Engineering, Supramolecular Chemistry, Materials- and Nano-Science and Physics. The overall goal of HESPERUS is to generate new scientific and technological knowledge by combining supramolecularly engineered nanostructures (SENs), mostly based on organic semiconductors, with tailor-made interfaces to textured solid substrates and electrodes, for fabricating prototypes of two-terminal devices (s",{"id":707,"funder":7,"programme":8,"title":708,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":709},"cordis-marie-skłodowska-curie-actions-award-221581","Impact of climate change on light-related carbon fluxes in the Arctic Ocean","We currently witness in the Arctic: 1) a decrease in summer ice cover that exposes sea surface to solar radiation and physical forcings, 2) permafrost thawing and increased river runoff, both leading to an increase in the export to ocean of organic carbon previously sequestered in the Tundra, and 3) an increase in ultraviolet radiation. These three phenomena potentially favour a growing mineralization of organic carbon through photo-oxidation taking place in the surface layer of the ice-free Arc",{"id":711,"funder":7,"programme":8,"title":712,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":713},"cordis-marie-skłodowska-curie-actions-award-220798","Post-settlement events influence on coral population structure: A multi-scale analysis along a latitudinal gradient","Albeit recruitment processes are known to influence spatial patterns of adult coral assemblages, the relative influence of recruitment processes vs. post-settlement events in population maintenance remains poorly known. Yet, understanding how populations are maintained is pre-requisite for efficient management.  This program proposes to study the influence of post-settlement events on adult population structure in several habitats and islands of three regions following a latitudinal gradient: Au",{"id":715,"funder":7,"programme":8,"title":716,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":717},"cordis-marie-skłodowska-curie-actions-award-220360","Cytosolic iron metabolism in unicellular eukaryotic pathogens","Iron is an essential nutrient for virtually all living organisms and host iron availability plays a critical role in the host–pathogen relationship. Without effective mechanisms for acquisition, transport and utilization of iron, no organism especially parasites with high iron requirements, can survive. However, our knowledge about intracellular iron metabolism in eukaryotic pathogenic microorganisms is poor; it is not known, how iron is stored in the cell or how it is utilized. In the proposed ",{"id":719,"funder":7,"programme":8,"title":720,"piName":10,"institution":721,"country":34,"year":13,"amount":10,"abstract":722},"cordis-marie-skłodowska-curie-actions-award-220720","Reaction Sequencing: A concise asymmetric approach to the antibacterial pleuromutilin","THE UNIVERSITY OF MANCHESTER","Resistance to antibiotics is a major concern worldwide and has led to an urgent need to identify antibacterial agents with modes of action distinct from the established classes. The antibacterial natural product pleuromutilin is such a candidate and has been the focus of biological and medicinal studies in recent years. Unfortunately, pleuromutilin has poor pharmacokinetic properties and the compound is readily metabolised by enzymes. Although the natural product itself is not a very good drug, ",{"id":724,"funder":7,"programme":8,"title":725,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":726},"cordis-marie-skłodowska-curie-actions-award-221243","Co-evolution and implications of vector adaptation: A case study on seabird ticks and Borrelia","Many emerging infectious diseases and novel agricultural pests are attributed to the adaptation and spread of parasitic organisms to new hosts, but almost nothing is known about the characteristics of parasites with this potential and the implications of this shift for interacting organisms. In vector organisms, those that exploit a host to which they will transmit a microparasite, the evolution of host-associated divergence may be of particular importance, especially for the evolution of the mi",{"id":728,"funder":7,"programme":8,"title":729,"piName":10,"institution":655,"country":434,"year":13,"amount":10,"abstract":730},"cordis-marie-skłodowska-curie-actions-award-221167","Compositional Changes of Sedimentary Organic Matter from a 100-year Flood Deposit: Insights into Event-Driven Processes in the Coastal Ocean","In spite of their importance as sites of long-term burial of organic matter (OM), key questions remain regarding the factors controlling carbon sequestration in river subaqueous deltas. One of the salient, but poorly understood, features of these river-dominated ocean margins (RIOMARs) is their highly dynamic nature. Specifically, we lack quantitative understanding of the role that perturbation events, such as floods, play in the OM biogeochemistry of RIOMAR systems. To address this knowledge ga",{"id":732,"funder":7,"programme":8,"title":733,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":734},"cordis-marie-skłodowska-curie-actions-award-220240","Search for the sources of ultra-high-energy cosmic rays with the Pierre Auger Observatory: from Auger South data to seamless integration of trigger and aperture for Auger North for full-sky coverage","The key to identifying the sources of ultra-high energy cosmic rays lies in the detection of anisotropies in the distribution of arrival directions. This proposal regards the study of anisotropies with the Pierre Auger Observatory, an international project with significant European contribution, consisting of two matching cosmic ray detectors, one in each hemisphere, for full sky coverage. The Southern Auger Observatory in Argentina is taking data and approaching completion in 2008 with an instr",{"id":736,"funder":7,"programme":8,"title":737,"piName":10,"institution":721,"country":34,"year":13,"amount":10,"abstract":738},"cordis-marie-skłodowska-curie-actions-award-220035","Cage Complexes With Phosphonates","The proposal is to learn to use polymetallic cage complexes as building blocks for larger zero-dimensional nano-objects. The approach to be adopted will be to use phosphonate and related ligands to link these cages via a carboxylate displacement reaction that has been developed in Manchester. Once made these compounds will be studied by X-ray crystallography and their magnetic properties examined using a variety of techniques.",{"id":740,"funder":7,"programme":8,"title":741,"piName":10,"institution":742,"country":107,"year":13,"amount":10,"abstract":743},"cordis-marie-skłodowska-curie-actions-award-220335","New computational tools for the modelling of correlations in quantum systems","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","The aim of this project is to use insights from exactly solvable models in order to improve the accuracy of quantum Monte Carlo methods for the modelling of correlated quantum systems such as ultracold atomic gases, nuclear matter and non-conventional superconductors. This will lead to a more precise understanding of the quantum correlations that exist in such systems and will allow to extend these insights to nuclear matter, neutron-rich atomic nuclei or neutron stars. The project also aims to ",{"id":745,"funder":7,"programme":8,"title":746,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":747},"cordis-marie-skłodowska-curie-actions-award-221035","Enlightenment on America, America on Enlightenment: historical writing in debate and the shaping of eurocentrism at the end of the Eighteenth century","\"Enlightenment on America, America on Enlightenment (AMEN) will investigate how the dispute about the New World in the 1770-80s addressed both the construction of a European consciousness and the attempt to provincialize Europe, as a first result of the crisis of the European (Spanish and British) Empires.  I propose a dual track enquiry, focusing on the confrontation between the History of America (1777) by W. Robertson – Scottish historian of the strongest and richest existing European empire–",{"id":749,"funder":7,"programme":8,"title":750,"piName":10,"institution":721,"country":34,"year":13,"amount":10,"abstract":751},"cordis-marie-skłodowska-curie-actions-award-219913","NanoPorous Anodic Oxides for Functionalization of Metal Surfaces","The project examines the mechanisms of formation of nanoporous anodic oxides. Nanoporous anodic oxides are important to the protection of metals against corrosion and wear. They have attracted renewed interest due to the potential for long range ordering of pores, with applications in nanotechnological systems. Currently, long-range pore order is achieved empirically. However, the proper understanding of growth mechanisms will enable systematic tailoring of oxide properties. The researcher will ",{"id":753,"funder":7,"programme":8,"title":754,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":755},"cordis-marie-skłodowska-curie-actions-award-220368","Adapting Robot Behavior based on Interaction","Having robots that are able to understand, communicate and coordinate with humans executing daily tasks is one of the dreams of society.  Moreover, when people interact with robots, they expect the robots to behave in a certain manner, and tend to apply them social models, similarly as how they behave when meeting a new person. Therefore, besides typical perception, reasoning and motion abilities (which have been largely studied so far), the robots also need to have certain abilities to enhance ",{"id":757,"funder":7,"programme":8,"title":758,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":759},"cordis-marie-skłodowska-curie-actions-award-220892","Molecular Mechanisms underlying the link between the vitamin K-dependent proteins, Gas6 and protein-S, and phagocytosis of apoptotic cells during cell differentiation processes","The anti-coagulant factor protein-S and its structural homologue Gas6, two vitamin K-dependent proteins, are ligands for the Tyro3\u002FAxl\u002FMer family of related tyrosine kinase receptors. Protein-S is the major factor responsible for serum-stimulated phagocytosis of apoptotic cells. The phenotypes associated with the invalidation of genes encoding Tyro3\u002FAxl\u002FMer, further revealed the implication of protein-S and Gas6, in regulating apoptotic cell phagocytosis.  We hypothesise that protein-S and Gas6 ",{"id":761,"funder":7,"programme":8,"title":762,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":763},"cordis-marie-skłodowska-curie-actions-award-221276","Catalytic Asymmetric Reductive Amination of Ketones","The need for direct catalytic transformations with economy of matter, solvent and catalyst is a challenge for modern chemistry towards clean and environmentally friendly processes. The objective of this project is to perform the enantioselective reductive amination of ketones in one pot without isolation of intermediates by using multi-functional catalysts, which should be able to promote condensation of an amine with a ketone, and catalyse the enantioselective reduction (hydrogenation) of proch",{"id":765,"funder":7,"programme":8,"title":766,"piName":10,"institution":721,"country":34,"year":13,"amount":10,"abstract":767},"cordis-marie-skłodowska-curie-actions-award-220239","Hamiltonian Actions and Their Singularities","In this project I intend to substantially advance research in different fields in contemporary symplectic geometry. The project is articulated in five sections: A. Singular symplectic and Poisson reduction of cotangent bundles. I will focus in an unfinished topic in the theory of singular reduction: its application to cotangent bundles. I will study the fibered structure of the singular reduced spaces in the Poisson and symplectic cases. B. Singular reduction in generalized complex geometry. In ",{"id":769,"funder":7,"programme":8,"title":770,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":771},"cordis-marie-skłodowska-curie-actions-award-221026","Covariant quantization of the superstring","The proposal aims at investigating several aspects of the recently proposed pure spinor formalism  for the quantization of the superstring in a way that keeps all the symmetries manifest.    The problem we intend to study has become more and more pressing in recent years, because of the importance and relevance of string theory backgrounds containing fluxes for Ramond-Ramond fields. They appear in the context of gauge\u002Fgravity dualities, in the string description of black holes and in cosmologica",{"id":773,"funder":7,"programme":8,"title":774,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":775},"cordis-marie-skłodowska-curie-actions-award-221827","Atmospheric HumiditY DistRibution and the impAct of MIxing and TRAnsport in the free troposphere","Understanding the processes that control the distribution of water vapour, the Earth's dominant greenhouse gas, is central to understanding climate. This project proposes to determine the combined effect of transport and mixing as well as micro-physical processes on the distribution of water vapour in the free troposphere. It will integrate theoretical knowledge acquired from idealised models with wind data sets and tracer measurements. The outcome of this approach is intended to contribute to a",{"id":777,"funder":7,"programme":8,"title":778,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":779},"cordis-marie-skłodowska-curie-actions-award-219483","P4 as precursor for metal phosphide nanoparticles and N2 activation and reduction to organic derivatives","There are two different aspects in the project: i) the use of P4 in the synthesis of nanocristals of metal-phosphide and ii) fixation and activation of nitrogen and its reduction to organic derivatives. i) Synthesis of nanocrystals MxPy Usually the syntheses of these species imply the thermal decomposition (at high temperature) of a metallic precursor and a P atom donor in the presence of a mixture of a solvent\u002Fligand. Normally P atom donor is TOP ligand. The main objective of our project is the",{"id":781,"funder":7,"programme":8,"title":782,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":783},"cordis-marie-skłodowska-curie-actions-award-221392","Theory Applied to Real Embedded Systems","Our project, entitled Theory Applied to Real Embedded Systems (TARES), aims to bridge a gap between theory and practise for the design of Embedded Systems. We are going to apply recent advanced theories and tools developed for timed systems to the design of existing and commercialised software products which are based on the L4 micro-kernel technology. A micro-kernel is an operating system that provides a restricted set of services; the micro-kernel L4 provides threads, basic scheduling, inter-p",{"id":785,"funder":7,"programme":8,"title":786,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":787},"cordis-marie-skłodowska-curie-actions-award-221874","Evolution in island birds: testing patterns and investigating mechanisms","Species on islands are widely believed to undergo similar evolutionary changes as an adaptation to the island environment, a process referred to as the ‘island syndrome’. These changes affect morphological, reproductive, physiological and behavioural traits such as sexual selection. Evolutionary change on islands is believed to relate to genetic (e.g. bottleneck) and ecological factors (e.g. release from natural enemies such as parasites and predators). However, very few broad-scale tests of the",{"id":789,"funder":7,"programme":8,"title":790,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":791},"cordis-marie-skłodowska-curie-actions-award-219755","COMPLEMENT AND ATHEROSCLEROSIS: MOLECULAR MECHANISM OF C1 ACTIVATION BY ENZYMATICALLY MODIFIED LOW-DENSITY LIPOPROTEINS","Atherosclerosis is considered to be a chronic inflammatory process. Arterial inflammation that precedes plaque development is caused by accumulation of LDL (low density lipoproteins) in the extracellular matrix of the vessels. These LDL particles are modified by a number of processes, including enzymatic degradation, aggregation and oxidation. Complement is also emerging as an important factor in this process: complement activation and formation of the terminal C5b-9 membrane attack complex were",{"id":793,"funder":7,"programme":8,"title":794,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":795},"cordis-marie-skłodowska-curie-actions-award-219821","MOLECULAR DESIGN OF NOVEL PHARMACEUTICAL COMPOUNDS BASED ON TRANSITION STATE STRUCTURES ACCESSED VIA KINETIC ISOTOPE EFFECTS: AN EXPERIMENTAL AND THEORETICAL STUDY","This project will contribute towards the molecular design of analogues of transition state structures associated with the degradation of therapeuticals. It will train an essentially computational chemist in experimental techniques, allowing her to become an independent research with broad experience in isotopic studies. The specific experimental training objective of the project is the determination of kinetic isotope effects to interpret the reaction mechanisms of degradation. This will require",{"id":797,"funder":7,"programme":8,"title":798,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":799},"cordis-marie-skłodowska-curie-actions-award-220270","Conflict Management, Cross-border relations and the Struggle for maritime Hegemony in the North Atlantic (XVIth-XVIIth centuries)","War between the French and Spanish crowns, the two Grand Powers of the sixteenth century, had important consequences in shaping collective identities and cross-border relations of frontier communities of both monarchies. That was the case of the Basque maritime provinces of Guipúzcoa in Spain, and Labourd in France. The hostility between these two frontier communities was not limited to the borderland region but in fact extended to the high-sea and beyond. The conflict embraced the Atlantic, not",{"id":801,"funder":7,"programme":8,"title":802,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":803},"cordis-marie-skłodowska-curie-actions-award-221464","ACcurate Reconstruction In PET: Fully 3D PET reconstruction with compressed scatter system matrix","In the fight against cancer, Positron Emission  Tomography (PET) can provide 3D images of metabolic processes (i.e. of cells in action) in the body and contributes to diagnosis and treatment. Two-dimensional PET scanners (2D PET) have been replaced by three-dimensional PET machines combined with a CT (3D PET\u002FCT). This led to complementary anatomical information (from the CT) and increased sensitivity (less noise in the images). However, the increased sensitivity comes along with an increased det",{"id":805,"funder":7,"programme":8,"title":806,"piName":10,"institution":742,"country":107,"year":13,"amount":10,"abstract":807},"cordis-marie-skłodowska-curie-actions-award-221448","Oxylipin signalling in plant defence against pathogens","Plants recognize invading pathogens and trigger an array of signalling events eventually leading to a resistance response that prevents or limits pathogen growth in planta. One signalling event upon pathogen infection is the formation of lipid derived oxylipins. In the animal physiology a broad signalling role of fatty acid derived molecules (eicosanoid family of lipid signals) have been well established. Increasing evidence is emerging that plant oxylipins have a similar complex and vital biolo",{"id":809,"funder":7,"programme":8,"title":810,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":811},"cordis-marie-skłodowska-curie-actions-award-220280","Magnetic mechanisms at the nanoscale studied by themal probe: nanocaloriometry and heat released","The continuous reduction of particle size in materials science has opened up new possibilities of producing materials at small length scales. The potential applications derived from the new properties of these materials span along multiple disciplines. In particular, magnetism at the nanoscale is the basis for new spintronic physics and devices. Whereas the production of nanoparticles, nanoclusters or multilayers of magnetic materials is widely spread, the understanding of phase transitions, spe",{"id":813,"funder":7,"programme":8,"title":814,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":815},"cordis-marie-skłodowska-curie-actions-award-220056","Migrant workers across European Labour markets. Mobility, citizenship and urban resources in the pre-industrial cities - XVIth-XVIIIth century","The project focus on mobility related to one of the central element of every society: labour market. One of the reasons more frequently adduced at the base of the choice of emigrate is the research of a job. Many scholars have analysed migratory chains and professional specializations of ethnic groups , stressing as immigrants communities were able to conquer relevant places on the labour market. Therefore, the fact that immigrants were not secondary actors on the labour market stage is ascertai",{"id":817,"funder":7,"programme":8,"title":818,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":819},"cordis-marie-skłodowska-curie-actions-award-220686","Diagram Based Reasoning","Diagrams are massively used in many reasoning processes and in the very practice of science; however, there is in general no consensus about the reasons why a diagram can be successfully used, and whether it represents only an auxiliary aid for reasoning or is something more fundamental for it.  The aim of the present project is the in depth investigation into the capacity of diagrams to convey information and supporting reasoning and inferences, which is necessary for a general evaluation of th",{"id":821,"funder":7,"programme":8,"title":822,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":823},"cordis-marie-skłodowska-curie-actions-award-219380","Quantitative analysis of atomic polarization and protein-ligand electrostatic interactions via charge density studies in proteins: insights from ultra-high resolution crystallography","X-ray crystallography at ultra-high resolution enables to observe the deformation of the atomic electron densities due to chemical bonding and intermolecular interactions. These can be quantitatively analysed via charge density studies, a mature and dynamic branch of modern crystallography, which provides important chemical information (charges, bond order, nucleophilicity…) on the atoms. For the analysis of the increasing number of protein structures measured at subatomic resolution, LCM3B has ",{"id":825,"funder":7,"programme":8,"title":826,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":827},"cordis-marie-skłodowska-curie-actions-award-219828","Nanoporous Materials and Supramolecular Clusters for Light Induced Electronic Switches","Molecular framework materials recently have been shown to possess immensely rich host-guest chemistry; their porous lattices are capable of highly selective host-guest properties that include reversible guest and ion exchange, heterogeneous catalysis, and gas storage and separation. It was realized that by further exploitation of the porous nature of metal-organic frameworks in combination with spin crossover centres, molecular sensing materials can be generated, whereby the spin crossover sites",{"id":829,"funder":7,"programme":8,"title":830,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":831},"cordis-marie-skłodowska-curie-actions-award-220395","Conditional Measurements in Quantum Optics for Application in Quantum Information","This project points to the experimental realization of suitably designed optical states for quantum communications uses. The quantum state will be conveniently manipulated by its projection on another one of predictable properties. The process will be realized by means of a conditional measurement performing a post-selection of the beam by monitoring a suitable observable on a fraction of it. The novel aspect of the proposed research relies on the application of this methods to multimode radiati",{"id":833,"funder":7,"programme":8,"title":834,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":835},"cordis-marie-skłodowska-curie-actions-award-221812","The functional significance of sex and death in phytoplankton differentiation","The coccolithophorid Emiliania huxleyi is a globally important phytoplankton species with a major role in ocean carbon cycling and the production of the climate active gas DMS, yet almost all information on this organism comes from the diploid, not the haploid phase. We propose to characterize the inherent and dynamic properties of the haploid and diploid stages and address whether sex and programmed cell death represent alternative outcomes of stress response pathways. Our research is motivated",{"id":837,"funder":7,"programme":8,"title":838,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":839},"cordis-marie-skłodowska-curie-actions-award-220008","The role of RNA interference in antibacterial responses of Caenorhabditis elegans","RNA interference (RNAi) induces gene silencing and is involved in host responses to pathogens. Faced with the bacterium Serratia (S.) marcescens, Caenorhabditis (C.) elegans responds with a behavioural response (lawn avoidance). Since mutation of the RNAi gene rde-4 impairs lawn avoidance, RNAi seems to be involved. S. marcescens infection leads to upregulation of antimicrobial peptide genes in C. elegans. Our hypothesis is that RNAi is involved in controlling this transcriptional response. This",{"id":841,"funder":7,"programme":8,"title":842,"piName":10,"institution":843,"country":844,"year":13,"amount":10,"abstract":845},"cordis-marie-skłodowska-curie-actions-award-219889","Trimeric Bacterial Autotransporters","HELSINGIN YLIOPISTO","FI","Bacterial adhesins play a crucial role in pathogen-host interactions, initiating infections by adhesion to the extracellular matrix and to cell surface proteins prior to invasion. A family of non-fimbrial adhesins, the trimeric autotransporter adhesins (TAAs), has recently been described in gram-negative pathogens. The common biological role of all these TAAs is to mediate the interaction of pathogenic bacteria with their hosts. There is an increasing body of evidence that TAAs represent highly ",{"id":847,"funder":7,"programme":8,"title":848,"piName":10,"institution":843,"country":844,"year":13,"amount":10,"abstract":849},"cordis-marie-skłodowska-curie-actions-award-221195","miRNA and tooth development","Teeth form as appendages of embryonic ectoderm and their development is regulated by similar mechanisms to other ectodermal organs like hairs and glands. More than 300 genes are currently known to be involved in tooth development. However, the mechanisms that regulate gene expression at specific times and locations are only partially understood. The most interesting open questions concern the mechanisms of the initial acquisition of organ specificity and the regulation of stem cells. microRNAs (",{"id":851,"funder":7,"programme":8,"title":852,"piName":10,"institution":853,"country":854,"year":13,"amount":10,"abstract":855},"cordis-marie-skłodowska-curie-actions-award-221716","Controllable global illumination for film production","UNIVERZITA KARLOVA","CZ","The ultimate objective of the project is to start a new interdisciplinary computer graphics research group in the return host under the direction of the fellow. This leading position will allow him to fully exploit the skills acquired during the outgoing stage at the renowned Cornell University Program of Computer Graphics, and will be the foundation of his long-term independent research career.  The central source of the new skills will be the execution of the proposed research, where our goal ",{"id":857,"funder":7,"programme":8,"title":858,"piName":10,"institution":677,"country":434,"year":13,"amount":10,"abstract":859},"cordis-marie-skłodowska-curie-actions-award-219361","Intellectual relations between Western Europe and Latin America, 1918-1939","My research analyses how intellectual relations between Latin America and Europe in the interwar years played into the crisis of liberal models of nation-building and the rise of introspective forms of nationalism in Latin America. Although scholars have commonly stressed European ‘influences’ in Latin American thought, the ways in which Latin Americans strategically appropriated ideas from the Old World and the networks that facilitated this appropriation have been scarcely studied for the inte",{"id":861,"funder":7,"programme":8,"title":862,"piName":10,"institution":617,"country":94,"year":13,"amount":10,"abstract":863},"cordis-marie-skłodowska-curie-actions-award-221097","Examining Oscillatory Dynamics with Magnetoencephalography and Intracranial Electroencephalography","The scientific goal of this project is to use magnetoencephalography (MEG) and intracerebral electroencephalography (iEEG) to gain a better understanding of subcortical and abnormal cortical oscillatory dynamics. The first specific aim of this project is to apply the most sophisticated techniques currently available to resolve the activity of deep brain structures, such as the amygdala, hippocampus, brainstem, and cerebellum, using noninvasive MEG recordings. Time-frequency analysis may be bette",{"id":865,"funder":7,"programme":8,"title":866,"piName":10,"institution":867,"country":87,"year":13,"amount":10,"abstract":868},"cordis-marie-skłodowska-curie-actions-award-220808","Dissecting the cytosolic tRNA import process in mitochondria of the unicellular green alga Chlamydomonas reinhardtii","UNIVERSITE DE LIEGE","During evolution, plant mitochondrial genomes underwent multiple rearrangements leading to the loss of genetic information. One of the consequences is that the number of mitochondrial encoded tRNA genes is not sufficient to ensure plant mitochondrial translation. In order to compensate this deficiency, cytosolic tRNAs have to be imported into mitochondria. Although this phenomenon is an essential process for mitochondrial biogenesis in most eukaryotic cells, it remains poorly understood.  The un",{"id":870,"funder":7,"programme":8,"title":871,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":872},"cordis-marie-skłodowska-curie-actions-award-219636","Quantum phases of a two-dimensional Bose gas","The proposed project aims at the experimental study of two-dimensional (2D) quantum degenerate Bose gases. In a first stage we will explore the coherence properties of the gas below the critical temperature of the Kosterlitz-Thouless transition. One of our objectives is to reveal the superfluid character of the gas. For this purpose we will rotate the trapped cloud to excite particular collective modes, which are expected to reveal the quenched moment of inertia. Subsequently, we will investigat",{"id":874,"funder":7,"programme":8,"title":875,"piName":10,"institution":677,"country":434,"year":13,"amount":10,"abstract":876},"cordis-marie-skłodowska-curie-actions-award-219528","As seen from North-East Asia: Potential and limits of the EU as a strategic actor","This research project explores the potential, and the limits, of the EU as a strategic actor in North-East Asia. It does so by focusing on a comparative analysis between EU motivations and aspirations towards China on space and defence matters and the perceptions and reactions of Chinese on the one hand and of Japanese, Taiwanese, South Korean and American policy makers on the other hand. The project is informed by and relates to the literatures on European foreign policy and the international p",{"id":878,"funder":7,"programme":8,"title":879,"piName":10,"institution":677,"country":434,"year":13,"amount":10,"abstract":880},"cordis-marie-skłodowska-curie-actions-award-219417","The achievement of an area of freedom, security and justice through the EU external relations","This project concerns the way the European Union (EU) can build an area of freedom, security and justice by making use of its powers to enter into international agreements with third countries. The EU has recently acquired the competence to legislate in this area. Very recently, the European Council has put forward the idea that the EU internal action is not enough to build such an area. Challenges to the EU external borders such as illegal immigration and threatens to the EU internal security s",{"id":882,"funder":7,"programme":8,"title":883,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":884},"cordis-marie-skłodowska-curie-actions-award-219223","Delay of Turbulence in Pipe Flow","The objective of this proposal is to delay the transition to turbulence in pipe flow.  The important motivation of reducing drag in fluid flows, and therefore to reduce the energy consumption required to drive them, has lead to significant breakthroughs in the study of flow control.  Only last year for the case of flow over a flat plate, turbulence was successfully delayed in experiment by using small controlled streaky disturbances to suppress the development of more unstable disturbances downs",{"id":886,"funder":7,"programme":8,"title":887,"piName":10,"institution":721,"country":34,"year":13,"amount":10,"abstract":888},"cordis-marie-skłodowska-curie-actions-award-219533","Exact Renormalisation Group and Phases of Many Fermion Systems","Proposed research is concerned with theoretical study of phase transitions in  many-fermion systems in a framework of the exact renormalisation group (ERG) approach. This method allows for a nonperturbative treatment of the evolution  of the physical systems with some momentum\u002Flength scale. I intend to develop the ERG-based theoretical description of phase diagrams in a variety of many-fermion systems, ranging from cold atoms to quark matter. I particular, I plan to explore BEC-BCS transition in",{"id":890,"funder":7,"programme":8,"title":891,"piName":10,"institution":445,"country":94,"year":13,"amount":10,"abstract":892},"cordis-marie-skłodowska-curie-actions-award-220926","The contribution of magma-carbonate interactions in the upper crust to volcanic CO2 emissions: quantitative constraints from experimental petrology, isotope geochemistry and thermal modelling","Mt. Etna and Popocatépetl, the most important subaerial sources of volcanic CO2 show evidence of interactions with the carbonate rocks forming their sedimentary basement. The present project aims at quantifying the contribution of magma-carbonate interactions in the upper continental crust to massive CO2 production in these volcanic areas. Carbonate assimilation will be investigated by hydrothermal experiments and thermal modelling. The experiments will be performed at magmatic conditions (press",{"id":894,"funder":7,"programme":8,"title":895,"piName":10,"institution":896,"country":34,"year":13,"amount":10,"abstract":897},"cordis-marie-skłodowska-curie-actions-award-219890","Evolution of reproductive barriers and its implications for adaptive speciation","THE UNIVERSITY OF SHEFFIELD","Perhaps the most basic question about the process of speciation is whether or not it is an adaptive progress. Recent studies suggest that natural selection and adaptation may play a more significant role in the early stages of divergence and the evolution of reproductive isolation than previously thought. This ‘adaptive speciation’ may be particularly common where there is partial spatial separation between habitats, such as on the steep environmental gradients that characterize sea-shore habita",{"id":899,"funder":7,"programme":8,"title":900,"piName":10,"institution":901,"country":87,"year":13,"amount":10,"abstract":902},"cordis-marie-skłodowska-curie-actions-award-221427","Linking redox and hormonal signalling in Arabidopsis plants with altered levels of a stress-inducible glycosyltransferase","VIB VZW","UDP-glycosyltransferases catalyze the addition of sugars to a wide range of small molecules thereby altering their activity, solubility and transport. In Arabidopsis, over 100 glycosyltransferase genes are annotated, however, only a limited number of these have been characterized. Arabidopsis UGT74E2 is an indole-3-butyric acid (IBA)-glycosyltransferase expressed in the root expansion zone and in the margins of leaf base and petioles. UGT74E2 transcripts are highly inducible by various biotic an",{"id":904,"funder":7,"programme":8,"title":905,"piName":10,"institution":901,"country":87,"year":13,"amount":10,"abstract":906},"cordis-marie-skłodowska-curie-actions-award-221684","STUDY THE ROLE OF OXYGEN SENSORS PROLYL HYDROXYLASE DOMAIN (PHD) PROTEIN IN OBESITY AND TYPE II DIABETES","Various alterations of metabolism are a central characteristic of physiological disorders and diseases, including cancer, obesity, type 2 diabetes (T2D) and the metabolic syndrome (MS) and are as such a major burden on national budgets. Thus, there is an urgent need to further understand the various processes that determine the occurence of metabolic alterations, predominantly obesity and T2D and to develop strategies to provide therapeutic aid. Several intrinsic factors either predetermine or c",{"id":908,"funder":7,"programme":8,"title":909,"piName":10,"institution":368,"country":34,"year":13,"amount":10,"abstract":910},"cordis-marie-skłodowska-curie-actions-award-220901","Study of coherent non-linear optical response of nanoparticles and application to multiphoton imaging in cell biology","The objective of this research project is to develop a novel multiphoton microscopy technique and to investigate its application to selected problems in cell biology which require sensitive three-dimensional imaging, in-vivo and real time. This novel technique is based on the detection of the resonant coherent non-linear optical response (four-wave mixing) of colloidal quantum dots (CQDs) to explore their application as bio-labels beyond their fluorescence properties. This method would retain ma",{"id":912,"funder":7,"programme":8,"title":913,"piName":10,"institution":86,"country":87,"year":13,"amount":10,"abstract":914},"cordis-marie-skłodowska-curie-actions-award-219500","Pyramidal neuron polarity decisions during migration and axonal outgrowth in the developing mammalian cerebral cortex","During embryonic brain development, pyramidal projection neurons are born in the ventricular zone and migrate radially towards the upper part of the cortex to form the cortical plate. These neurons also have to develop dendrites and axons in order to make connections. Several brain diseases and mental illness derive from defects in neuronal migration and positioning or in axon-target interactions for the establishment of synaptic circuitry.  Studies with cultured pyramidal neurons have shown tha",{"id":916,"funder":7,"programme":8,"title":917,"piName":10,"institution":896,"country":34,"year":13,"amount":10,"abstract":918},"cordis-marie-skłodowska-curie-actions-award-220383","Generation of stable transgenic embryonic stem cell lines","Human embryonic stem cells (hESC) are pluripotent cells derived from blastocyst stage early embryos. Since the original publication a vast number of studies have described the differentiation of hESC and their potential in regenerative medicine. It is now well known that hESC might be used in cell replacement therapies in a number of severe degenrative diseases like Type I diabetes or Parkinson’s disease. In addition, hESCs and their derivatives could be used as tools in discovering new drugs an",{"id":920,"funder":7,"programme":8,"title":921,"piName":10,"institution":922,"country":151,"year":13,"amount":10,"abstract":923},"cordis-marie-skłodowska-curie-actions-award-221095","Work around the Clock: effects of shift work on cognitive performance and circadian organization in behavior and physiology","RIJKSUNIVERSITEIT GRONINGEN","The 24-h organization of modern economy challenges the daily organization of our internal biological rhythms. Under normal conditions, an orchestra of body clocks, conducted by a central pacemaker in the hypothalamus (suprachiasmatic nucleus, SCN) synchronizes specific behavior and physiology to specific times of day, leading to optimal performance. Shift work conditions may reduce synchrony among body clocks, possibly leading to abnormal physiology and reduced cognitive function. Psychological ",{"id":925,"funder":7,"programme":8,"title":926,"piName":10,"institution":927,"country":62,"year":13,"amount":10,"abstract":928},"cordis-marie-skłodowska-curie-actions-award-221451","Dissecting the molecular basis of deleterious genetic interactions involving naturally occurring alleles in Arabidopsis","UNIVERSITE DE LAUSANNE","Natural genetic variation within populations largely determines phenotypic variation and is increasingly recognized as a critical factor in such diverse contexts as crop productivity or human disease susceptibility. For instance, diseases can be considered as quantitative traits, with disease occurring beyond a certain boundary along a spectrum. Whether a given allele confers a disease burden can depend on environmental factors, but also on the presence of particular alleles at other loci. Thus,",{"id":930,"funder":7,"programme":8,"title":931,"piName":10,"institution":932,"country":151,"year":13,"amount":10,"abstract":933},"cordis-marie-skłodowska-curie-actions-award-220089","When bad things happen to good brands. On how to deal with product-harm crisis","UNIVERSITEIT MAASTRICHT","Product-harm crises are prevalent in today’s marketplace. Notable examples include contaminated coca-cola in several European countries and salmonella poisoning in Brinta’s breakfast porridge. These crises can have a tremendous impact on society as well as on the affected companies. Moreover, the number of product recalls is on the rise both in the US and Europe. Not surprisingly, the European Union has realised the importance of product-harm crises to public safety and has fairly recently insta",{"id":935,"funder":7,"programme":8,"title":936,"piName":10,"institution":932,"country":151,"year":13,"amount":10,"abstract":937},"cordis-marie-skłodowska-curie-actions-award-221836","The arterial adventitia: a critical actor in atherosclerotic plaque progression and stability?","Background: The clinical outcome of cardiovascular diseases such as myocardial infarction and stroke is generally caused by rupture or erosion of an atherosclerotic plaque. While the contribution of the plaque intima and media to plaque initiation and progression are well acknowledged, that of the arterial perivascular tissue, the adventitia, is not established yet.  Hypothesis: Adventitial inflammation, which is partially modulated by adipocyte activity, profoundly impacts plaque progression an",{"id":939,"funder":7,"programme":8,"title":940,"piName":10,"institution":368,"country":34,"year":13,"amount":10,"abstract":941},"cordis-marie-skłodowska-curie-actions-award-220861","Becoming Intercultural - the Diversification of the Political Subject in Multicultural Societies A Theoretical and Practical Approach","It is agreed that multiculturalism (MC) has become one of the dominant discourses in Western political theory and practice concerning the needs and demands of weakened minorities, giving increasing attention to issues of identity and recognition of cultural difference. Despite nearly thirty years of political experiment and research, pressing questions concerning weakened minorities' status within Western democracies are still disputed.  Principally, this research project claims that issues of i",{"id":943,"funder":7,"programme":8,"title":944,"piName":10,"institution":932,"country":151,"year":13,"amount":10,"abstract":945},"cordis-marie-skłodowska-curie-actions-award-220181","Strategic Analysis of Flow Networks","Thanks to the decreased cost of transportation and communication, the world became a densely connected network. This is particularly true for economics. Regional developments affect the rest of the world. Similarly, global trends influence all regions. International trade connects world markets to the extent that the world prices are determined by a global process. The price of petrol is influenced by the Chinese economy, Middle East politics and the weather in the North Sea. The market for natu",{"id":947,"funder":7,"programme":8,"title":948,"piName":10,"institution":742,"country":107,"year":13,"amount":10,"abstract":949},"cordis-marie-skłodowska-curie-actions-award-219860","Production of hypoallergenic soy products exhibiting bioactive peptides throughout fermentation technology","With respect to allergenicity, soybean ranks in the “big 8” of the most allergenic foods and the incidence rate is projected to markedly increase with increasing consumption. The aim of this research is to provide an adequate fermentation process that will allow reducing allergenicity enhancing the safety and availability of soy-derived products to sensitive individuals providing at the same time new bioactive peptides that may prevent age-related chronic diseases. These approaches will be of si",{"id":951,"funder":7,"programme":8,"title":952,"piName":10,"institution":200,"country":41,"year":13,"amount":10,"abstract":953},"cordis-marie-skłodowska-curie-actions-award-221554","Graft engineering to improve allogeneic stem cell transplantation","Allogeneic stem cell transplantation (ASCT) is a curative therapy for various haematological malignancies. Obtaining suitably matched donors, problems with graft versus host disease (GVHD) and infection, however, limit the wider application of this therapy. Knowledge from previous studies has highlighted the need for a more effective and integrated approach to address these issues. This project examines how our knowledge of immune cell trafficking can be exploited in conjunction with haploidenti",{"id":955,"funder":7,"programme":8,"title":956,"piName":10,"institution":957,"country":313,"year":13,"amount":10,"abstract":958},"cordis-marie-skłodowska-curie-actions-award-220894","The New Players in the Marine Nitrogen Cycle: Benthic Foraminifera","AARHUS UNIVERSITET","Generally, anaerobic respiration of nitrate is regarded as a bacterial process. In addition to bacteria only three eukaryotes were known to have the potential to reduce nitrate and nitrous oxide. However, very recently three species of benthic foraminifera were found to respire nitrate completely to dinitrogen gas. To be able to do so they store high concentrations of nitrate in their cell (Risgaard-Petersen et al. 2006). Benthic foraminifera are unicellular eukaryotes that are among the most su",{"id":960,"funder":7,"programme":8,"title":961,"piName":10,"institution":368,"country":34,"year":13,"amount":10,"abstract":962},"cordis-marie-skłodowska-curie-actions-award-219762","Coherent ultrafast spectroscopy and manipulation of excitonic Q-bits","The research field of the proposed subject is the coherent, ultrafast spectroscopy and manipulation of individual excitonic state confined within a semiconductor quantum dot. Due to technological advances in light detectors and microscopy techniques, the investigation of the emission properties of individual, localized light emitters is now routinely possible. These investigations have led to significantly improved insight into the electronic dynamics of these systems and their temporal instabil",{"id":964,"funder":7,"programme":8,"title":965,"piName":10,"institution":742,"country":107,"year":13,"amount":10,"abstract":966},"cordis-marie-skłodowska-curie-actions-award-220644","“Ortega y Gasset’s Philosophy of Life and His Idea of Europe”","Abstract: “Ortega y Gasset’s Philosophy of Life and His Idea of Europe”  The aim of the philosophical research project “Ortega y Gasset’s Philosophy of Life and His Idea of Europe” is to enable a twofold synthesis under a systematic perspective: The first stage consists in developing a philosophical notion of culture as well as a notion of cultural consciousness within an interdisciplinary bridging of Philosophy and Spanish Studies. The second stage will be marked by a shift from cultural philos",{"id":968,"funder":7,"programme":8,"title":969,"piName":10,"institution":932,"country":151,"year":13,"amount":10,"abstract":970},"cordis-marie-skłodowska-curie-actions-award-219597","Normative or Strategic Power Europe?  Conceptualising the European Union’s Power in the Wider European Neighbourhood","This project aims at conceptualising the European Union’s (EU) power in the wider European neighbourhood through studying the compliance responses of non-EU countries to the EU’s conditions for further inclusion in the European integration project and how these responses are affected by domestic views of the purpose of the EU’s actions. Drawing on empirical evidence from southern and eastern neighbouring states, the project will first investigate the driving forces behind the EU’s policy in the ",{"id":972,"funder":7,"programme":8,"title":973,"piName":10,"institution":974,"country":107,"year":13,"amount":10,"abstract":975},"cordis-marie-skłodowska-curie-actions-award-220341","In vivo studies and screens for new factors that promote or suppress tumor metastasis","UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE","Metastasis is the process whereby a primary tumor (usually highly malignant in nature) spreads to distant locations in the body. Understanding step-by-step how particular confined tumors acquire invasiveness and\u002For spreading potential is a scientific challenge that can help us to develop new strategies for metastatic cancer prevention or treatment. In mouse models and in humans, the inactivation of the E-cadherin gene and the activation of genes of the SNAIL family are markers of the initiation ",{"id":977,"funder":7,"programme":8,"title":978,"piName":10,"institution":979,"country":12,"year":13,"amount":10,"abstract":980},"cordis-marie-skłodowska-curie-actions-award-220948","“Solid phase synthesis, biophysical study and biological evaluation of cyclic glycopeptides for inhibition of protein protein interactions”","UNIVERSITY OF GALWAY","Dr. Jarikote, an Indian national who has recently completed his PhD in Germany and is currently working with Prof. Dr. Paul Murphy. It is proposed that Dr. Jarikote will work on solid phase synthesis of cyclic glycopeptides and their biophysical characterization with a view to generating novel inhibitors of protein-protein interactions, in particular those that involve a-helices. He will also receive training in carbohydrate chemistry, scaffolds, NMR and molecular modelling and their application",{"id":982,"funder":7,"programme":8,"title":983,"piName":10,"institution":901,"country":87,"year":13,"amount":10,"abstract":984},"cordis-marie-skłodowska-curie-actions-award-221740","Chagas' disease - Inhibitor discovery and optimization for Trypanosoma cruzi trans-sialidase","This proposal focus on finding new potential lead compounds to inhibit the trans-sialidase of Trypanosoma cruzi, as a step towards finding a drug against Chagas’ disease. A new high through-put enzyme assay will be used to scan a large library of small molecules and in combination with in silico pharmacophoric modelling this is expected to provide new types of scaffolds as well as identifying important functionalities in the ligand. Based on the obtained information a set of ligands will be desi",{"id":986,"funder":7,"programme":8,"title":987,"piName":10,"institution":200,"country":41,"year":13,"amount":10,"abstract":988},"cordis-marie-skłodowska-curie-actions-award-221246","Double infection by HSV-2 and HIV: how does HSV-2 infection facilitate for HIV infection?","Globally, more than 40 million people are currently infected with HIV-1, with the vast majority of infections initiated at mucosal surfaces and approximately half of the world people now living with HIV are women. Herpes simplex type 2 (HSV-2) is one of the most common sexually transmitted viral diseases (STD) with an estimated prevalence of up to 50% among the female population worldwide giving rise to genital lesions and ulcers. Genital tract inflammation due to STD, such as HSV-2, increases e",{"id":990,"funder":7,"programme":8,"title":991,"piName":10,"institution":974,"country":107,"year":13,"amount":10,"abstract":992},"cordis-marie-skłodowska-curie-actions-award-220731","Analysis of Neuregulin-1 function in the maturation of cortical GABAergic interneurons: Implications for the etiology of schizophrenia","Schizophrenia is a psychiatric illness affecting nearly 1% of the population that is though to arise as a consequence of abnormal brain development.  Structural deficits are relatively subtle in schizophrenia; however, there is evidence for a reduced volume of the neocortex, probably linked to perturbed development of the neuropil, and significant alterations in GABAergic neurotransmission in patients with schizophrenia.  Recent genetic studies suggest that Neuregulin-1 (Nrg1) and its receptor E",200,{"programme":8,"total":995,"withPiName":996,"firstYear":997,"lastYear":998,"countryCount":999,"perYear":1000,"topInstitutions":1076,"topCountries":1152},26094,19,1988,2027,53,[1001,1003,1006,1009,1012,1015,1018,1020,1023,1026,1029,1032,1035,1038,1041,1044,1047,1050,1053,1056,1059,1062,1065,1068,1071,1074],{"year":997,"count":1002},1,{"year":1004,"count":1005},2003,74,{"year":1007,"count":1008},2004,586,{"year":1010,"count":1011},2005,868,{"year":1013,"count":1014},2006,641,{"year":1016,"count":1017},2007,553,{"year":13,"count":1019},591,{"year":1021,"count":1022},2009,712,{"year":1024,"count":1025},2010,787,{"year":1027,"count":1028},2011,838,{"year":1030,"count":1031},2012,901,{"year":1033,"count":1034},2013,1005,{"year":1036,"count":1037},2014,1009,{"year":1039,"count":1040},2015,1232,{"year":1042,"count":1043},2016,1231,{"year":1045,"count":1046},2017,1209,{"year":1048,"count":1049},2018,1353,{"year":1051,"count":1052},2019,1340,{"year":1054,"count":1055},2020,1314,{"year":1057,"count":1058},2021,1688,{"year":1060,"count":1061},2022,1362,{"year":1063,"count":1064},2023,1495,{"year":1066,"count":1067},2024,1522,{"year":1069,"count":1070},2025,1781,{"year":1072,"count":1073},2026,1532,{"year":998,"count":1075},396,[1077,1080,1083,1086,1089,1092,1095,1098,1101,1104,1107,1110,1113,1116,1119,1122,1125,1128,1131,1134,1137,1140,1143,1146,1149],{"name":1078,"count":1079},"Centre National de la Recherche Scientifique CNRS",790,{"name":1081,"count":1082},"The Chancellor Masters and Scholars of the University of Cambridge",636,{"name":1084,"count":1085},"Kobenhavns Universitet",614,{"name":1087,"count":1088},"Chancellor, Masters and Scholars of the University of Oxford",579,{"name":1090,"count":1091},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",484,{"name":1093,"count":1094},"Imperial College of Science Technology and Medicine",428,{"name":1096,"count":1097},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",383,{"name":1099,"count":1100},"University of London",347,{"name":1102,"count":1103},"Katholieke Universiteit Leuven",280,{"name":1105,"count":1106},"The University of Birmingham",247,{"name":1108,"count":1109},"Eidgenoessische Technische Hochschule Zuerich",224,{"name":1111,"count":1112},"Aarhus Universitet",220,{"name":1114,"count":1115},"Universita Ca' Foscari  Venezia",219,{"name":1117,"count":1118},"University of Bristol",213,{"name":1120,"count":1121},"Ecole Polytechnique Federale de Lausanne",182,{"name":1123,"count":1124},"The University of Edinburgh",181,{"name":1126,"count":1127},"Universita Degli Studi di Padova",177,{"name":1129,"count":1130},"Universitat Wien",175,{"name":1132,"count":1133},"University of Leeds",169,{"name":1135,"count":1136},"Universiteit van Amsterdam",159,{"name":1138,"count":1139},"Universitetet I Oslo",156,{"name":1141,"count":1142},"Universiteit Utrecht",152,{"name":1144,"count":1145},"Technische Universiteit Delft",142,{"name":1147,"count":1148},"University of Warwick",141,{"name":1150,"count":1151},"Institut National de la Sante Et de la Recherche Medicale",139,[1153,1155,1157,1159,1161,1163,1165,1167,1169,1171,1173,1175,1177,1179,1182,1184,1186,1188,1190,1193,1195,1198,1201,1204,1207],{"name":34,"count":1154},5982,{"name":94,"count":1156},2854,{"name":107,"count":1158},2844,{"name":48,"count":1160},2362,{"name":434,"count":1162},2058,{"name":151,"count":1164},1624,{"name":313,"count":1166},1173,{"name":62,"count":1168},1075,{"name":87,"count":1170},996,{"name":41,"count":1172},788,{"name":558,"count":1174},634,{"name":12,"count":1176},608,{"name":700,"count":1178},487,{"name":1180,"count":1181},"PT",482,{"name":844,"count":1183},313,{"name":306,"count":1185},277,{"name":854,"count":1187},256,{"name":163,"count":1189},168,{"name":1191,"count":1192},"TR",147,{"name":176,"count":1194},137,{"name":1196,"count":1197},"SI",113,{"name":1199,"count":1200},"CY",99,{"name":1202,"count":1203},"HU",97,{"name":1205,"count":1206},"LU",59,{"name":1208,"count":1209},"LT",56]