[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2009":3,"awarded-stats-msca-postdoctoral-fellowship":921},{"awarded":4,"total":920},[5,16,23,30,36,42,48,54,61,67,74,80,87,94,100,106,112,117,123,129,133,139,144,149,153,158,164,170,176,182,188,192,196,201,206,210,214,218,222,226,230,236,242,246,250,254,258,262,266,270,274,278,283,287,291,295,300,306,311,316,321,325,329,333,337,342,346,350,354,359,363,369,373,377,381,385,389,395,400,405,411,415,420,424,429,433,437,441,445,449,453,458,462,466,470,474,478,483,487,491,495,499,503,507,511,515,519,523,527,531,535,541,546,550,554,558,562,566,570,574,578,582,586,590,594,598,602,606,610,614,618,624,628,632,636,640,644,648,652,656,660,664,668,672,676,681,685,689,693,698,702,706,711,716,720,725,730,734,738,742,746,750,755,761,765,769,773,777,782,786,790,794,799,803,807,811,816,820,824,829,833,837,842,847,852,857,861,865,869,874,878,882,886,890,894,898,902,906,911,916],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-marie-skłodowska-curie-actions-award-980058","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","Novel flavour and fragrance molecules from native chinese flora",null,"KUNMING INSTITUTE OF BOTANY CHINESE ACADEMY OF SCIENCES","CN",2009,"€40,000","This proposal seeks to identify new natural molecules from the Chinese flora that have potential application in the European flavour and fragrance industry. In order to achieve this, the techniques used for extraction, isolation and selection of target compounds must first be substantially improved.Improvements in the isolation, identification and selection of target molecules will be achieved through the novel use of a single machine combining gas chromatography, mass spectrometry and olfactive",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-marie-skłodowska-curie-actions-award-980064","MICROBIAL COMPETITION AS A DRIVING FORCE OF PRIMED SOIL ORGANIC MATTER DECOMPOSITION","INSTITUTE OF PHYSICOCHEMICAL AND BIOLOGICAL PROBLEMS IN SOIL SCIENCE, RUSSIAN ACADEMY OF SCIENCES","RU","€25,515","Mineralization activity of soil microorganisms is a crucial parameter in evaluating the biosphere potential to regulate CO2 level in the atmosphere. Priming effects (PE) are strong changes in the turnover of native soil organic matter (SOM) induced by the input of fresh organic matter to the soil. In the course of priming, large amounts of C, N and other nutrients can be released or immobilized in soil on a very short timescale. Hence, the intensity of carbon sequestration and turnover in soil a",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":26,"country":27,"year":13,"amount":28,"abstract":29},"cordis-marie-skłodowska-curie-actions-award-980065","Secure High-Speed Information Processing","INSTITUTE OF PHYSICS, AZERBAIJAN NATIONAL ACADEMY OF SCIENCES","AZ","€15,700","Control and synchronization of chaotic dynamics has become an area of great interest in recent years. Specific attention has been given to the opportunities to exploit optical chaos to effect private or secure communications. Recent work emanating from the EU OCCULT project demonstrated chaotic message transmission over an installed commercial optical fibre network. The key element of this capability is a chaotic laser diode which enables high-speed ( Gb\u002Fs) data communications. Complementary wor",{"id":31,"funder":7,"programme":8,"title":32,"piName":10,"institution":33,"country":12,"year":13,"amount":34,"abstract":35},"cordis-marie-skłodowska-curie-actions-award-980060","Glazing behaviour in a fire environment","UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA","€49,100","The breakage of glass pane during a fire could influence the fire behaviour due to the change from impermeable barriers to large ventilation sources, resulting in the occurrence of the dangerous backdraft phenomena or post flashover flames emerging outside of the openings leading to rapid fire spread to other floors and in the most severe cases even to adjacent buildings.The project will address the thermally induced stress response of glass to the heat fluxes from fire. Two separable physical p",{"id":37,"funder":7,"programme":8,"title":38,"piName":10,"institution":39,"country":20,"year":13,"amount":40,"abstract":41},"cordis-marie-skłodowska-curie-actions-award-980024","High-pressure phase transitions in poly-amorphic systems of semi-conducting elements","INSTITUTE OF SOLID STATE PHYSICS, RUSSIAN ACADEMY OF SCIENCES","€56,134","The project is aimed to acquisition the experimental information about the transformations occurred in amorphous silicon and germanium within wide pressure and temperature intervals, characterization of the different amorphous phases formed under high pressure. This will be done by in situ high-pressure experiments using Raman, infrared spectroscopy and X-ray diffraction. The incoming phase period is based in the University College of London (UCL) using the range of diamond anvils cells installe",{"id":43,"funder":7,"programme":8,"title":44,"piName":10,"institution":45,"country":12,"year":13,"amount":46,"abstract":47},"cordis-marie-skłodowska-curie-actions-award-980053","Treatment of endocrine disrupting chemicals in wastewater","BEIJING NORMAL UNIVERSITY","€49,286","This proposal aims to support the collaboration of leading researchers to study the degradation of endocrine disrupting chemicals (EDCs), with the broad aim of supporting the development of dynamic world-class human resources in the European research system. The proposal consists of a scientific project and scientific and complimentary training. This project aims to investigate the use of ferrate, photocatalytic and photo-electrocatalytic oxidation for degrading EDCs in wastewater and to optimis",{"id":49,"funder":7,"programme":8,"title":50,"piName":10,"institution":51,"country":20,"year":13,"amount":52,"abstract":53},"cordis-marie-skłodowska-curie-actions-award-980074","Femtosecond modifications in glasses with application to novel laser designs","INSTITUTE OF APPLIED PHYSICS OF RUSSIAN ACADEMY OF SCIENCES","€36,566","The objective of the fellowship is twofold: first, gaining new fundamental knowledge on the phenomena underlying the process of glass modification upon irradiation by femtosecond (fs) pulses, and second, application of this knowledge to optimise glass composition, the process of photo-fabrication, and finally to the design and fabrication of novel devices.   Although fs writing has already been applied to create a variety of guiding structures, there is no proper understanding of its general app",{"id":55,"funder":7,"programme":8,"title":56,"piName":10,"institution":57,"country":58,"year":13,"amount":59,"abstract":60},"cordis-marie-skłodowska-curie-actions-award-980054","Development of freely available predictive models based on simple chemical descriptors","UZBEK ACADEMY OF SCIENCE; INSTITUTE OF GEOLOGY AND GEOPHYSICS","UZ","€36,000","A system of optimal descriptors for modeling by means of quantitative structure property\u002Factivity relationships (QSPR\u002FQSAR) biochemical endpoints will be developed. As representation of molecular structure, hydrogen filled graph (HFG), graph of atomic orbitals (GAO), simplified molecular input line entry system (SMILES), and International Chemical Identifier (InChI) will be examined. The GAO is an attempt to take into account atom structure in the QSPR\u002FQSAR analyses.The GAO is an original innova",{"id":62,"funder":7,"programme":8,"title":63,"piName":10,"institution":64,"country":12,"year":13,"amount":65,"abstract":66},"cordis-marie-skłodowska-curie-actions-award-980057","Advanced imaging and measurement for multiphase flow","INSTITUTE OF MECHANICS, CHINESE ACADEMY OF SCIENCES","€48,800","The principal aim of the research is to develop a new generation of a non-invasive flow instrument for the measurement of flowrates and imaging of the internal structure of complex, unsteady two- or three-phase flows. The research is multi disciplinary covering the aspects of flow mechanics and metering, process tomography, signal processing and multi-variable data fusion. The instrument, based on electrical impedance tomography (EIT) sensors coupled with the principles of electromagnetic and Ve",{"id":68,"funder":7,"programme":8,"title":69,"piName":10,"institution":70,"country":71,"year":13,"amount":72,"abstract":73},"cordis-marie-skłodowska-curie-actions-award-980033","Phyto-chemical and pharmacological study of plants used in traditional medicine in Cameroon","UNIVERSITY OF YAOUNDE I","CM","€77,914","Natural product chemistry continues to provide a rich source of pharmacologically active compounds and therefore extensively contributes to the chemical repertoire of medicinal chemistry. The development of new drugs still very much relies on the utilisation of physiologically active natural products.The proposed project focuses on the isolation, structural characterization, and determination of the biological activity of secondary metabolites produced by plants of Psorospermum species. In Camer",{"id":75,"funder":7,"programme":8,"title":76,"piName":10,"institution":77,"country":12,"year":13,"amount":78,"abstract":79},"cordis-marie-skłodowska-curie-actions-award-980029","The application of Protistan diversity and community analysis, an integrated approach to Water Quality Assessment","OCEAN UNIVERSITY OF CHINA","€59,100","The urgent need for robust, high-throughput method to assess water quality and aquatic biodiversity, as a proxy for environmental health, are clear. This provides an obvious target for initial efforts resolving molecular fingerprints for total diversity and identification of potential indicator organisms. Eukaryotes exhibit a significant level of morphological diversity that has traditionally been used to define Linnean names. Molecular systematics provides a separate and powerful tool for phylo",{"id":81,"funder":7,"programme":8,"title":82,"piName":10,"institution":83,"country":84,"year":13,"amount":85,"abstract":86},"cordis-marie-skłodowska-curie-actions-award-980072","Retinal development in flat fish larvae- the effect of dietary essential fatty acids","UNIVERSIDAD DE LA REPÚBLICA","UY","€65,940","The current proposal seeks to evaluate the effects of highly unsaturated fatty acids (HUFA) on the development of vision in marine fish larvae. The study will consider the effect of natural diets with differing contents of HUFA on the development of the retinal tissue in larvae of the flatfishes Pleuronectes platessa and Paralichthys orbignyanus.HUFA play an important role as an energy storage and membrane components, including photoreceptor cells in the retina. Marine fish have a limited capaci",{"id":88,"funder":7,"programme":8,"title":89,"piName":10,"institution":90,"country":91,"year":13,"amount":92,"abstract":93},"cordis-marie-skłodowska-curie-actions-award-980039","Effects of systemic annonacin exposure in transgenic mice expressing normal or mutant human tau protein: role of environment-gene interactions in neuro- degeneration","FUNDAÇÃO DE AMPARO E DESENVOLVIMENTO DA PESQUISA","BR","€60,000","Experimental and epidemiological studies have identified natural substances, such as the acetogenin annonacin, that could be associated with mechanisms of neurodegeneration in some forms of tauopathies. Many mutations in the taugene have also been associated with familial cases of tauopathies, such as the frontotemporal dementias with parkinsonism linked to chromosome 17 (FTDP-17). However, it is still not clear what is the relative contribution of genetic and environmental factors to the observ",{"id":95,"funder":7,"programme":8,"title":96,"piName":10,"institution":97,"country":12,"year":13,"amount":98,"abstract":99},"cordis-marie-skłodowska-curie-actions-award-980044","Development of Low Stress No Distortion Welding for Industrial Applications.","BEIJING AERONAUTICAL MANUFACTURING TECHNOLOGY RESEARCH INSTITUTE (BAMTRI)","€45,500","Current methods of fabrication involving welding usually result in significant welding distortion problems. Thin walled structures are particularly susceptible in the automotive, shipbuilding and aerospace industries. The cost and time required correcting for distortions can be significant (for example in Europe annual estimates are in excess of 100M). This results in reduced competitiveness and the creation of uneconomic designs, which are produced to compensate for anticipated distortions.   L",{"id":101,"funder":7,"programme":8,"title":102,"piName":10,"institution":103,"country":20,"year":13,"amount":104,"abstract":105},"cordis-marie-skłodowska-curie-actions-award-980061","Advanced multi-metallic alloy coatings: investigation of thermal decomposition mechanism of metalorganic precursors upon chemical vapour deposition","NIKOLAEV INSTITUTE OF INORGANIC CHEMISTRY, SIBERIAN BRANCH OF RUSSIAN ACADEMY OF SCIENCES","€44,100","The project is developed to generate fundamental knowledge on the decomposition mechanisms of metalorganic (MO) precursors that are used for the preparation of coatings composed of complex metallic alloys (CMA) by metalorganic chemical vapour deposition (M OCVD). Such coatings present an extraordinary combination of properties that are mutually excluding in conventional materials.Unfortunately, these properties are attained within a very narrow compositional range. The project is also developed ",{"id":107,"funder":7,"programme":8,"title":108,"piName":10,"institution":109,"country":110,"year":13,"amount":10,"abstract":111},"cordis-marie-skłodowska-curie-actions-award-237091","Structural Analysis of Mathematical Proofs","Université Paris Diderot-Paris 7","FR","Proof Theory is the branch of mathematical logic that investigates formal proof systems modelling mathematical reasoning. There are different types of proof systems, each having its own advantages and disadvantages. A certain class of proof systems (Gentzen-type systems) has the interesting property of exhibiting a geometric structure in proofs. Logical and proof-theoretic problems that are formulated in the context of these systems are thus susceptible to analysis by geometric and combinatorial",{"id":113,"funder":7,"programme":8,"title":114,"piName":10,"institution":115,"country":10,"year":13,"amount":10,"abstract":116},"cordis-marie-skłodowska-curie-actions-award-236243","Advancing percutaneous heart valve repair in children through the development of new cardiac imaging strategies","UNIVERSITY COLLEGE LONDON","The development of non-surgical methods for the treatment of heart valve disease in children as well as in adults has recently become a reality. The increased use of these methods would improve patient comfort, avoid prolonged hospital care and stay, and enable patients to return to normal daily activities in a shorter time, ultimately reducing healthcare costs. We currently have the largest worldwide experience of implanting percutaneous valves into the pulmonary position, and have safely perfo",{"id":118,"funder":7,"programme":8,"title":119,"piName":10,"institution":120,"country":121,"year":13,"amount":10,"abstract":122},"cordis-marie-skłodowska-curie-actions-award-236099","Nonlinearity management of atomic and optical systems","UNIVERSIDADE DE LISBOA","PT","The proposal is devoted to the investigation of nonlinear management of electromagnetic waves in optical systems and matter waves in Bose-Einstein condensates. The problems te be addressed include: investigation of processes of modulational instability in systems with a strong nonlinearity management; developments of the theory of surface states in nonlinear optical lattices and photonic crystals; control of tunneling in multi-well trap potentials for the condensates with the temporal management",{"id":124,"funder":7,"programme":8,"title":125,"piName":10,"institution":126,"country":127,"year":13,"amount":10,"abstract":128},"cordis-marie-skłodowska-curie-actions-award-236484","Combined indoor\u002Foudoor Wireless Network Planning","UNIVERSITY OF BEDFORDSHIRE","UK","Wireless communications technologies have experienced some of the fastest technological innovations in the last few decades. In the near future, a large portion of the access network will go wireless. It is estimated that 2\u002F3 of voice and over 90% of data services using wireless communications take place indoors. Hence, indoor solutions like picocells (indoor base stations) deployed by the operators, or femtocells (indoor home base stations) deployed directly by the users, have been recently pro",{"id":130,"funder":7,"programme":8,"title":131,"piName":10,"institution":126,"country":127,"year":13,"amount":10,"abstract":132},"cordis-marie-skłodowska-curie-actions-award-221380","MAC and Network Layers Optimization","The High Speed Downlink Packet Access (HSDPA) has been introduced in order to improve the downlink capability by the third Generation Partnership Project (3GPP) in the Wide-band Code Division Multiple Access (WCDMA) standard. Due to the increasing demands for uplink intensive data services such as ftp and multimedia uploads etc., the concept of the High Speed Uplink Packet Access (HSUPA) was subsequently introduced.  Together, these downlink and uplink technologies are collectively known as the ",{"id":134,"funder":7,"programme":8,"title":135,"piName":10,"institution":136,"country":137,"year":13,"amount":10,"abstract":138},"cordis-marie-skłodowska-curie-actions-award-236522","Elemental abundance analysis of substructures in the Galaxy disk. Implications for disk formation","MAX IV Laboratory, Lund University","SE","Elemental abundances in stars have proved to be an important tool in the study of the formation and evolution of the Milky Way. Combining the elemental abundances with the motions of the stars provide even stronger evidence for past and present evolution. Much recent work has focused on the identification of stellar streams in the Milky Way halo. Some of these streams have been identified as ruptured dwarf galaxies that are currently being engulfed by our Galaxy. However, it is the thin disk tha",{"id":140,"funder":7,"programme":8,"title":141,"piName":10,"institution":142,"country":110,"year":13,"amount":10,"abstract":143},"cordis-marie-skłodowska-curie-actions-award-236605","AROMATIC FOLDAMERS AS DRUG DELIVERY CARRIERS","UNIVERSITE BORDEAUX I","The Huc group is a world leading research team in the fields of Biomimetic and Bioorganic Chemistry. One of group’s main contributions is focused on the synthesis, structural elucidation and biological application of aromatic oligoamides. These compounds adopt exceptionally stable folded conformations, helices, stabilised by intramolecular hydrogen bonds and - interactions. The high structural predictability, tunability, ease of synthesis and resistance to hydrolysis of such foldamers has led to",{"id":145,"funder":7,"programme":8,"title":146,"piName":10,"institution":147,"country":110,"year":13,"amount":10,"abstract":148},"cordis-marie-skłodowska-curie-actions-award-221456","MACROPHAGES ON THE ROAD TO B?","UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II","Transcription factors have been shown to play an important role in the tight control and for fine-tuning of lineage decisions that take place during the development of the various different cell types present in blood. Interestingly, certain factors appear to be essential for genetic programming of specific lineages, and in the absence of such factors, lineage promiscuity has been observed. We have now derived a novel mouse model system to further address the role of specific myeloid transcripti",{"id":150,"funder":7,"programme":8,"title":151,"piName":10,"institution":115,"country":10,"year":13,"amount":10,"abstract":152},"cordis-marie-skłodowska-curie-actions-award-236021","Neural bases of temporal processing in the human brain","Although perception of time is fundamental to human and animal behavior, there is no consensus in the scientific community with respect to the neural mechanisms that enable us to actually perceive and process time. This proposal seeks to answer three fundamental questions addressing the nature and localization of the underlying neuronal mechanisms enabling humans to use temporal information and keep track of time. The specific aims are: (i) To determine whether neural mechanisms of temporal proc",{"id":154,"funder":7,"programme":8,"title":155,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":157},"cordis-marie-skłodowska-curie-actions-award-221060","Functional diversity in plant communities: the role of environmental filters","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","Recent studies argue that plant functional traits should be the corner stone for a more quantitative and predictive approach to biodiversity and species coexistence. In this perspective, functional diversity, i.e. the diversity and range of functional traits, should be a new and promising ecological metrics through its predictive potential. Mechanisms, by which plant traits are selected across environmental filters to further constitute a plant community, remain to be established, however. The m",{"id":159,"funder":7,"programme":8,"title":160,"piName":10,"institution":161,"country":162,"year":13,"amount":10,"abstract":163},"cordis-marie-skłodowska-curie-actions-award-220682","Array of coupled nanoresonators","DANMARKS TEKNISKE UNIVERSITET","DK","A novel system based on NEMS resonators will be developed. An array of coupled nanoresonators with a transduction based in the strain of thin layers of metal will be developed. To do that, analytical studies, FEM simulations, design and fabrication will be performed. The characterization will be done in three steps: measure frequency response of the system and characterization of the mass sensitivity (outgoing phase) and its use as a biosensor (return phase).",{"id":165,"funder":7,"programme":8,"title":166,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":169},"cordis-marie-skłodowska-curie-actions-award-219357","Precipitation pattern effects on plant-soil microbial interactions","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","CH","Global environmental change is predicted in Europe to result in increased frequency and intensity of extreme climatic events, including severe droughts and intense precipitation events. Such changes will affect plant physiology, microbial activity and soil nutrient cycling, inducing changes in ecosystem functioning, with expected consequences on in plant community composition, net primary productivity and carbon balance. Thus, it is crucial to consider the effect of precipitation patterns of con",{"id":171,"funder":7,"programme":8,"title":172,"piName":10,"institution":173,"country":174,"year":13,"amount":10,"abstract":175},"cordis-marie-skłodowska-curie-actions-award-234999","Predicting the Properties of Carbonaceous Pitches via Molecular Modeling","ETHNICON METSOVION POLYTECHNION","EL","The dramatic escalation in energy prices over the past year has brought a new sense of urgency to the development of strong but lightweight advanced materials for increased fuel efficiency. With one-fifth the weight of steel and equal or superior properties, advanced carbon materials are clearly a key solution to today’s energy problems. Because of their exceptional stiffness and ultra-high thermal conductivity (4 times that of copper), the potential market and value to society of inexpensive, p",{"id":177,"funder":7,"programme":8,"title":178,"piName":10,"institution":179,"country":180,"year":13,"amount":10,"abstract":181},"cordis-marie-skłodowska-curie-actions-award-236009","Exploring Quantum Entanglement using Spins in Diamond","TECHNISCHE UNIVERSITEIT DELFT","NL","We propose to create and detect quantum entanglement between a single spin in the solid state and a single photon and in a second step entanglement between two distant spins. This experiment will be realized using Nitrogen-Vacancy (NV) centers in diamond, that are exceptionally well suited for this due to their very long spin coherence time and a strong and stable optical transition that allows spin-photon mapping. An NV center in a superposition of spin states will be optically excited, and the",{"id":183,"funder":7,"programme":8,"title":184,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":187},"cordis-marie-skłodowska-curie-actions-award-234920","A Chemical Approach to Lead-free Nanosolders","UNIVERSITAT WIEN","AT","Physical, electronic and thermodynamic properties of small particles (nano-particles) differ significantly from those of the bulk materials, and the depression of the melting temperature below the melting point of the bulk has been known for a long time. This dependence of the melting temperature on the particle size is not restricted to any particular material and may therefore also be exploited to lower the melting temperatures of lead-free solders. At the same time, the high-temperature solde",{"id":189,"funder":7,"programme":8,"title":190,"piName":10,"institution":161,"country":162,"year":13,"amount":10,"abstract":191},"cordis-marie-skłodowska-curie-actions-award-237517","Linking inducible chemical defences and phytoplankton population dynamics","Marine phytoplankton contribute approximately 50% of the global primary production. Despite this, our understanding of the driving forces and processes that structure phytoplankton communities is still rudimentary. Community structure is of fundamental importance for the ecosystem function and food-web dynamics. Some phytoplankton species acts as carbon sinks, others as sources, and community structure may therefore determine the direction of ocean–atmosphere CO2 exchange, with corresponding inf",{"id":193,"funder":7,"programme":8,"title":194,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":195},"cordis-marie-skłodowska-curie-actions-award-220464","Modern Methods of Operator Algebras for Time-Frequency Analysis","The project is on the interface between time-frequency analysis and  operator algebras.  In the last decade  the relevance of operator  algebras in time-frequency analysis and Gabor analysis has evolved  mainly due to the contributions of Groechenig, Janssen and their  collaborators.  The operator algebras that have appeared in these works  are twisted group C*-algebras or more generally crossed products. In  the present project the proposer wants to explore the deeper structure  of crossed prod",{"id":197,"funder":7,"programme":8,"title":198,"piName":10,"institution":199,"country":180,"year":13,"amount":10,"abstract":200},"cordis-marie-skłodowska-curie-actions-award-221742","Novel kind of graphene based materials and its blend with polythiophenes","STICHTING RADBOUD UNIVERSITEIT","Diamond and graphite, the two well-known allotropes of carbon, were familiar from the ancient times. Fullerenes, the third form of carbon, were discovered in 1985 and carbon nanotubes in 1991. Thus three dimensional (3D) (diamond and graphite), 1D (nanotubes) and 0D (fullerenes) allotropes were known. Since the breakthrough in 2004 that two dimensional allotropes of carbon, graphene has been reported. It can be used in molecular electronics applications, such as field-effect transistors, researc",{"id":202,"funder":7,"programme":8,"title":203,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":205},"cordis-marie-skłodowska-curie-actions-award-219607","MEDITERRANEAN CLIMATE EVOLUTION AND CONNECTION WITH THE ATLANTIC OCEAN: INFERENCES FROM HIGH-RESOLUTION MARINE ARCHIVES","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","Paleoclimate records are important tools for understanding climate modifications and contextualizing recent anthropogenic perturbations in climate changes relative to the natural variability in the Earth climate system. For the marine environment, reliable instrumental measurements of climatic variables such as sea surface temperature, salinity and dynamics of the water masses are generally limited to the last 150 years, and are too geographically scanty and temporally non-continuous to encompas",{"id":207,"funder":7,"programme":8,"title":208,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":209},"cordis-marie-skłodowska-curie-actions-award-235038","The mass and growth of (obscured) black holes and their host galaxies since the Universe was young","The goal of this proposal is to establish a method for the quantification of fundamental active galactic nucleus (AGN) properties, i.e., black hole (BH) masses and accretion rates, in high-redshift and obscured AGN. We aim to use infrared spectra from the Spitzer and Herschel space telescopes to study the kinematics and fluxes of gas emission lines originating from the AGN narrow-line region (NLR). Our first results indicate that the mid-infrared (MIR) NLR line widths follow the relation between",{"id":211,"funder":7,"programme":8,"title":212,"piName":10,"institution":161,"country":162,"year":13,"amount":10,"abstract":213},"cordis-marie-skłodowska-curie-actions-award-236184","WDM Optical Phase-modulated Radio-over-Fiber Systems","Fast, reliable and everywhere are the qualifiers for access to information. Therefore to provide both high capacity and flexibility, the transport of wireless and wireline signals is converging into a common telecommunication infrastructure. In this project, we focus on the study of wavelength-division-multiplexing (WDM) optical phase modulated radio-over-fiber (RoF) system, which is a promising solution to implement broadband seamless wireless-wireline access networks. One important feature of ",{"id":215,"funder":7,"programme":8,"title":216,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":217},"cordis-marie-skłodowska-curie-actions-award-220494","Physics of cracks and damage","The objective of PhyCracks is to provide a statistical description of the basic processes occurring at the microstructure scale during the failure of materials (damage, plasticity…). This description will result in a model of crack propagation that ultimately will lead to predictive constitutive laws less phenomenological than the ones currently used by engineers. While existing theories allow to estimate quite precisely mechanical properties like Young modulus for instance, the failure properti",{"id":219,"funder":7,"programme":8,"title":220,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":221},"cordis-marie-skłodowska-curie-actions-award-236530","Protein engineering for encapsulation and intracellular transport","The main goal of this project is to develop a system for effective encapsulation and transport of negatively charged guests into living cells using an enginnered protein capsid. The research in prof. Hilvert's group demonstrated that it is possible to engineer the inner surface of a capsid formed by lumazine synthase from Aquifex aeolicus (AaLS) to accept positively charged guests while retaining the icosahedral structure. In my project I will be addressing the following issues: - Engineering th",{"id":223,"funder":7,"programme":8,"title":224,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":225},"cordis-marie-skłodowska-curie-actions-award-235322","Roles and mechanisms of action of activin in skin cancer","The increase in skin cancer incidence in the past years has made the search for new therapeutic approaches to prevent or cure these malignancies a major research challenge. Importantly, the development of new therapies depends on a thorough understanding of the molecular mechanisms underlying the pathogenesis of these threatening disorders. The growth and differentiation factor activin A regulates a variety of processes, among them cutaneous homeostasis and repair. Most interestingly, recent res",{"id":227,"funder":7,"programme":8,"title":228,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":229},"cordis-marie-skłodowska-curie-actions-award-235323","Self-assembly of confined colloidal objects for the study of nano-optic phenomena","We have demonstrated the presence of attractive interactions arising in low ionic strength solution between charged soft-matter objects and highly curved regions of like-charged confining surfaces. These unexpected interactions result in stretching of DNA and trapping of colloidal particles in solution in a nanofluidic slit. This proposal seeks to further understand the attractive interactions arising between colloidal objects and like-charged confining walls in low-ionic-strength solution, in o",{"id":231,"funder":7,"programme":8,"title":232,"piName":10,"institution":233,"country":234,"year":13,"amount":10,"abstract":235},"cordis-marie-skłodowska-curie-actions-award-236667","Chip Integrated Hydrogen Generation-Storage-Power Micro System","RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN","DE","The primary objective of the proposal is the development of a chip integrated hydrogen generator based on polymer electrolyte membrane water electrolysis with on-board hydrogen storage and an option for a bi-functional operation (as a unitized regenerative microfuel cell). The output of the generated hydrogen should be high enough to feed up to 50 mW.cm-2 microfuel cell at continuous operation, while enabling hydrogen storage capable to compete the conventional secondary batteries. The goal will",{"id":237,"funder":7,"programme":8,"title":238,"piName":10,"institution":239,"country":240,"year":13,"amount":10,"abstract":241},"cordis-marie-skłodowska-curie-actions-award-220818","Dynamics of Automobile Demand","UNIVERSITY OF CYPRUS","CY","Understanding consumer behavior is an important task of economics. An automobile is the largest item most individuals will ever purchase (besides a home), hence economists have dedicated much effort in analyzing the factors that determine automobile purchase decisions. Important methodological advances in the 1990s have made possible the estimation of rich static demand models for differentiated products like automobiles. More recently, attention has shifted to dynamic aspects of consumer behavi",{"id":243,"funder":7,"programme":8,"title":244,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":245},"cordis-marie-skłodowska-curie-actions-award-237068","Rotating Micro-Detectors for Ultra-Sensitive and High-Resolution Analysis of Heterogeneous Matter with Magnetic Resonance: instrumentation, methodology and applications","Nuclear magnetic resonance technology is omnipresent in modern analytical science and biomedicine because of the detailed information it can provide both as a non-invasive imaging as well as a broadband spectroscopic tool. Three-dimensional molecular structure and dynamics and localized functional tomography are possible provided that the sample size is large enough for the technique to be sensitive. This project aims at further developing the recently introduced concept of rotating micro-detect",{"id":247,"funder":7,"programme":8,"title":248,"piName":10,"institution":173,"country":174,"year":13,"amount":10,"abstract":249},"cordis-marie-skłodowska-curie-actions-award-237087","The BIOTELEKINESY home-care service : a communication platform for the tele-monitoring and the tele-management of the elderly to detect locomotion disabilities and prevent fall","The context of our ageing population and the expenses explosion linked up with healthcare request for the elderly, innovative solutions strongly related to prevention, to an improvment of the quality of life and to an upholding of an independent life as long as possible. Therefore, the core of the BIOTELEKINESY project is to provide an innovative ICT based interface with a holistic approach to detect and prevent as earlier as possible in the daily environement of the elderly person, motion disab",{"id":251,"funder":7,"programme":8,"title":252,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":253},"cordis-marie-skłodowska-curie-actions-award-234813","Why do plants make (p)ppGpp?","Under stress bacteria accumulate the potent chemical messenger (p)ppGpp, which drives global changes in transcription that allow the bacteria to adapt and persist. Remarkably the ability to synthesise (p)ppGpp is conserved in plant chloroplasts, organelles that are descended from an ancient prokaryotic endosymbiont. However, very little is known about the role (p)ppGpp plays in plants. We propose to (a) artificially manipulate (p)ppGpp levels and analyse the downstream responses of the plant, an",{"id":255,"funder":7,"programme":8,"title":256,"piName":10,"institution":161,"country":162,"year":13,"amount":10,"abstract":257},"cordis-marie-skłodowska-curie-actions-award-237471","Vertical Structure of the Atmospheric Boundary Layer and Applications","Research on renewable energy sources becomes of crucial importance in view of global warming, fossil fuels crises and nuclear power dangers. Wind energy gradually takes bigger part of energy production in Western European countries and is planned to develop further. This process depends on new technologies (size, shape and materials of blades and higher turbines), but also specific meteorological research on vertical wind profile is required. Both the construction and energy production of new mo",{"id":259,"funder":7,"programme":8,"title":260,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":261},"cordis-marie-skłodowska-curie-actions-award-236664","Effective Interactions and correlations of ring polymers","Understanding the Physics of modern materials on a fundamental level is a key ingredient in the quest to develop novel materials with desired, tailored properties. In this sense, polymers, are in enormous interest nowadays, due to their numerous applications in biology and industry. The development of experimental techniques, such as atomic force microscopy (AFM) and optical tweezers, allow us to manipulate the topology of macromolecules, including the most common biological polymer, DNA. Topolo",{"id":263,"funder":7,"programme":8,"title":264,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":265},"cordis-marie-skłodowska-curie-actions-award-235943","Learning context dependent behavior: neural and synaptic mechanisms","Understanding how cognitive functions are implemented by biophysical processes in the brain is one of the most important and challenging goals of neuroscience. In the recent years, significant progress has been achieved by developing theoretical models for neural correlates of decision making, working memory, attention and representation of emotional value. These models were based on experimental evidence and they provided us with the basic building blocks for the study of more complex cognitive",{"id":267,"funder":7,"programme":8,"title":268,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":269},"cordis-marie-skłodowska-curie-actions-award-237646","Dynamic nuclear polarization - enhanced high resolution solid-state NMR spectroscopy for atomic 3D structure determination of functionalized nanotubes and other nano-sized objects","This project aims at developing the instrumentation and methodology required to perform solid-state sub-nanometer scale structural studies by Nuclear Magnetic Resonance (NMR). In the last decades NMR has proven to be a priceless tool to probe structure and dynamics of systems as diverse as glasses, metal surfaces, polymers and proteins, etc. However, the low sensitivity of the technique currently limits its outreach in material science, chemistry and biology. In order to overcome this limitation",{"id":271,"funder":7,"programme":8,"title":272,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":273},"cordis-marie-skłodowska-curie-actions-award-220680","Archaeal activity dynamics in marine snow vs. ambient water in coastal European Sea","Our knowledge on the marine nitrogen cycle has undergone some major revisions very recently with the discovery of novel pathways mediated by thus far unknown and partly unculturable prokaryotes. Among these new drivers of the nitrogen cycle are non-thermophilic Crenarchaea and Euryarchaea. Recently, Crenarchaea have been shown to harbor the amoA gene, responsible for the expression of ammonia monooxygenase, which represents a key enzyme in the nitrification step. The project aims at determining ",{"id":275,"funder":7,"programme":8,"title":276,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":277},"cordis-marie-skłodowska-curie-actions-award-235422","The Forest as Habitat in Transylvania of the 18th Century: Society, Economy and Environment in the Edge of the Hapsburg Empire","The central point of the proposal is the analysis of the interdependencies between rural communities and the natural environment of the forest in the 18th century Transylvania, as well as the perils to which the environment was exposed as a consequence of this relationship. At the same time, one will study the modes of perception by which the people approached their environment, thus being exposed also the contemporary normative procedures of acting on the environment, with the possible result o",{"id":279,"funder":7,"programme":8,"title":280,"piName":10,"institution":281,"country":174,"year":13,"amount":10,"abstract":282},"cordis-marie-skłodowska-curie-actions-award-220419","Nanomechanics of defects in solids: applications to nanolayers, nanoparticles, nanocrystals and biomaterials","ARISTOTELIO PANEPISTIMIO THESSALONIKIS","The central aim of the proposed project is to develop a general nanomechanics of defects framework for the understanding and prediction of structure-properties relationships of nanoscale materials, components, and devices. This framework will be suitable for metal nanoparticles and nanorods, nanolayered films and core\u002Fshell nanowires, ultrafine grained bulk nanostructures, as well as carbon nanotubes and protein membrane nanotubes. While standard continuum mechanics and dislocation theory have b",{"id":284,"funder":7,"programme":8,"title":285,"piName":10,"institution":173,"country":174,"year":13,"amount":10,"abstract":286},"cordis-marie-skłodowska-curie-actions-award-235196","Development of structural DEsign REcommendations for STeel ARches","The proposed study is aimed at the investigation of the nonlinear behaviour and the development of design rules and recommendations for steel arches in the form of European Standards for construction. Today, Eurocode 3 considers only straight members. Arches have to be designed according to the same methodology and the same values of parameters as straight members. Some authors have already proposed adjustments of these parameters in order to provide higher safety and economical design of arches",{"id":288,"funder":7,"programme":8,"title":289,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":290},"cordis-marie-skłodowska-curie-actions-award-236839","Systems Biology of Cancer Kinome","Protein kinases mediate most of the signal transduction events in cells by phosphorylation of specific substrates – modifying their activity, cellular location, and\u002For association with other proteins. The extremely critical role of kinases for critical cellular decisions came evident when an unexpectedly large number of kinases (120\u002F518) were found to be mutationally activated activated or their expression increased due to gene-amplification or translocation in many types of human cancer, sugges",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":204,"country":110,"year":13,"amount":10,"abstract":294},"cordis-marie-skłodowska-curie-actions-award-236376","Heavy Ion Collisions at the LHC: Strong coupling techniques for high density QCD","The study of nuclear matter under extreme conditions, where new states are predicted by Quantum Chromodynamics (QCD), is the new frontier on the physics of the strong interactions. The upcoming experimental program in ultra-relativistic heavy ion collisions at the CERN Large Hadron Collider, starting in 2009, is aimed at producing and studying a new state of matter, the Quark Gluon Plasma, and at the understanding of the fundamental properties of QCD, such as confinement and its phase diagram. T",{"id":296,"funder":7,"programme":8,"title":297,"piName":10,"institution":298,"country":137,"year":13,"amount":10,"abstract":299},"cordis-marie-skłodowska-curie-actions-award-221094","Characterization of Reactive Oxygen Species as Innate Immune System Mediators that Control Inflammation","GOETEBORGS UNIVERSITET","Biomedical research in the post genomic era will depend on the establishment of collaborative efforts between clinical and preclinical researchers, combining bedside medical research with experimental science. This project stems from initial gene expression studies on immune compromised patients with severe inflammatory disorders. The results allowed us to generate the hypothesis that reactive oxygen radicals are key anti-inflammatory agents in the immune system. We also embrace the novel idea t",{"id":301,"funder":7,"programme":8,"title":302,"piName":10,"institution":303,"country":304,"year":13,"amount":10,"abstract":305},"cordis-marie-skłodowska-curie-actions-award-236493","Ethical, Legal, and Social Aspects and Implications of Direct-to-Consumer Genetic Testing","KATHOLIEKE UNIVERSITEIT LEUVEN","BE","With ongoing genetic discoveries and improvements in technology, more genetic tests are made available in a clinical context than ever before. Along with the increase in genetic tests offered there has been a recent rise in companies providing various genetic tests directly-to-consumers (DTC) bypassing the traditional face-to-face meeting with a health care professional. DTC genetic tests have generated various concerns with regard to tests’ analytical and clinical validity, as well as clinical ",{"id":307,"funder":7,"programme":8,"title":308,"piName":10,"institution":309,"country":234,"year":13,"amount":10,"abstract":310},"cordis-marie-skłodowska-curie-actions-award-236798","Trophic diversity, resource compartmentation, and the stability of ecosystems","FREIE UNIVERSITAET BERLIN","Spatial and temporal variation in energy flow through food webs contributes to ecosystem stability. In stable food webs, energy is channelled through resource compartments, in which energy passes independently of other compartments. Higher-order consumers can derive energy from multiple compartments; even though energy flow through individual compartments varies, populations of higher-order consumers are relatively stable since resources in multiple compartments are more likely to be continuousl",{"id":312,"funder":7,"programme":8,"title":313,"piName":10,"institution":314,"country":180,"year":13,"amount":10,"abstract":315},"cordis-marie-skłodowska-curie-actions-award-220905","Natural and Artificially Influenced Swash-Groundwater Interactions Experiments","UNIVERSITEIT UTRECHT","Effective management of coastal erosion is a major stakes for the European Union. In a context of global warming and overpopulation of the coasts, the overall purpose of this project is to improve understanding of the hydrosedimentary processes affecting the instantaneous land-sea interface (the beachface), at the origin of an erosion or accretion of a coast. The objectives are:  (1) To study the impact of the various types of marine waves on the swash\u002Fbeach groundwater\u002Fsediment transit interact",{"id":317,"funder":7,"programme":8,"title":318,"piName":10,"institution":319,"country":127,"year":13,"amount":10,"abstract":320},"cordis-marie-skłodowska-curie-actions-award-237203","The evolution of post-orogenic landscapes: bedrock rivers, lithology and relief development","UNIVERSITY OF GLASGOW","Post-orogenic landscapes occupy by far and away the bulk of the Earth’s surface but their evolution remains under-researched and poorly understood, providing the central motivation for this proposal. The principal outcome will be the testing of competing models for post-orogenic landscape evolution. The proposal is strongly linked to studies that analyse how climatic and tectonic factors influence landscape evolution, and relies on leading-edge techniques such as cosmogenic nuclide analysis and ",{"id":322,"funder":7,"programme":8,"title":323,"piName":10,"institution":319,"country":127,"year":13,"amount":10,"abstract":324},"cordis-marie-skłodowska-curie-actions-award-236989","SMALL TO LARGE DEFORMATIONS OF UNSATURATED SOILS: AN APPLICATION TO EARTH STRUCTURES","In unsaturated soils, pores are filled partly by water and partly by air. Unsaturated soils occur naturally (as superficial ground above the water table) or in manmade structures (as compacted earth in infrastructure embankments, underground nuclear waste repositories and flood defences). Unsaturated soil mechanics has experienced significant advances during recent years, instigated by the use of compacted earth as sustainable building material and by the pressing need of the construction indust",{"id":326,"funder":7,"programme":8,"title":327,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":328},"cordis-marie-skłodowska-curie-actions-award-237034","Climate change, energetic constraints and susceptibility to environmental stressors in Antarctic seabirds: integrating stress physiology and population heterogeneity","In Antarctica, climate change has negative impacts on seabird populations. However, this change is likely to differentially affect birds depending on their age, experience and quality. This heterogeneous response to climate change deserves attention because it will affect the structure of populations and thus, their health status. This project aims to examine how age, experience and quality can functionally affect the way Antarctic seabirds respond to environmental perturbations. Moreover, we wi",{"id":330,"funder":7,"programme":8,"title":331,"piName":10,"institution":303,"country":304,"year":13,"amount":10,"abstract":332},"cordis-marie-skłodowska-curie-actions-award-235334","Exhaust Pipe noise radiation Modelling by Innovative Computational Aeroacoustics","As outlined in the Strategy Paper ‘Research for a Quieter Europe in 2020’, written by the CALM network and funded by the European Commission Research Directorate-General, significant research investments are needed to further reduce the road traffic noise in Europe. A major contributor to the noise, especially in urban environments, is the vehicle exhaust system. Noise attenuation of vehicle combustion engines is achieved by incorporating efficient mufflers in the exhaust systems. However, these",{"id":334,"funder":7,"programme":8,"title":335,"piName":10,"institution":319,"country":127,"year":13,"amount":10,"abstract":336},"cordis-marie-skłodowska-curie-actions-award-220220","ANISOTROPIC RESPONSE OF UNSATURATED SOILS: A MICROSTRUCTURAL APPROACH","The expression “unsaturated soil” is used in geotechnical engineering to identify a class of soils whose pores are partially filled with water and partially filled with air. Unsaturated soils occur naturally above the water table as a superficial ground layer, whose thickness depends on the balance of precipitation and evapo-transpiration and, hence, on the prevailing local climatic conditions. Unsaturated soils also occur in manmade structures that are built by compacted earth such as embankmen",{"id":338,"funder":7,"programme":8,"title":339,"piName":10,"institution":340,"country":234,"year":13,"amount":10,"abstract":341},"cordis-marie-skłodowska-curie-actions-award-235722","Nanoengineering of functional lanthanide tetrapyrrole systems","TECHNISCHE UNIVERSITAET MUENCHEN","The paradigm of the project is to develop a whole set of novel 2D and 3D nanostructures of next generation organic materials (lanthanide porphyroids) on metallic surfaces. This experience will help the researcher to become a principal investigator in the near future. The organic nanostructures will be created in ultra high vacuum conditions by molecular beam organic deposition on metallic monocrystalline substrates. The samples will be geometrically characterized by low temperature STM; electric",{"id":343,"funder":7,"programme":8,"title":344,"piName":10,"institution":303,"country":304,"year":13,"amount":10,"abstract":345},"cordis-marie-skłodowska-curie-actions-award-237202","Novel approaches to the study of enzymatic diffusion on single DNA molecules","In cells, enzymes are able to locate and sequence specifically bind to short regions of DNA in a compacted genome of many millions of bases. This fellowship will investigate the mechanism by which they achieve this remarkable feat by examining the behavior of single enzymes diffusing on single DNA molecules. The fellowship will focus on two main objectives. The first is to exploit novel DNA-labeling technology to investigate, for the first time at the single molecule level, the effect of DNA top",{"id":347,"funder":7,"programme":8,"title":348,"piName":10,"institution":314,"country":180,"year":13,"amount":10,"abstract":349},"cordis-marie-skłodowska-curie-actions-award-220178","Generalized complex 4-manifolds","We will study a notion of Lefschetz pencils for generalized complex 4-manifolds, aiming at results analogue to those of Donalson and Gompf in symplectic geometry stating that a 4-manifold has a symplectic structure if and only if it admits a Lefschetz pencil. To achieve the desired results we have to find the right definition of a Lefschetz pencil in the generalized complex setting. Earlier work of the candidate on this area has already shed some light into this question.  We will study the ques",{"id":351,"funder":7,"programme":8,"title":352,"piName":10,"institution":314,"country":180,"year":13,"amount":10,"abstract":353},"cordis-marie-skłodowska-curie-actions-award-235210","Power-integral points on elliptic curves","The study of Diophantine equations is one of the oldest branches of pure mathematics. The 20th century saw Siegel’s theorem about the finitness of integral points on elliptic curves, the negative solution of Hilbert’s 10th problem, Faltings' Theorem and the proof of Fermat’s Last Theorem. In the 21st century much work has already been done to resolve extensions of Hilbert’s 10th problem and to make Faltings' theorem effective. Moreover, solving generalized Fermat equations has, for example, led ",{"id":355,"funder":7,"programme":8,"title":356,"piName":10,"institution":357,"country":234,"year":13,"amount":10,"abstract":358},"cordis-marie-skłodowska-curie-actions-award-235798","microRNAs and Neurogenesis Control","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","Vertebrate brain development and function require the life-long regulation of neural stem cell maintenance and neuronal production. Recent evidence, in part obtained in the host laboratory, suggest that the microRNA miR-9 might be an important regulator of neurogenesis, by driving neural progenitors towards differentiation. Notably, injection of a miR-9 morpholino antisense oligonucleotide into zebrafish embryos decreases neuronal differentiation in the embryonic hindbrain. The spatio-temporal e",{"id":360,"funder":7,"programme":8,"title":361,"piName":10,"institution":357,"country":234,"year":13,"amount":10,"abstract":362},"cordis-marie-skłodowska-curie-actions-award-235689","Quantitative real-time multi-spectral optoacoustic tomography","Multi-spectral optoacoustic tomography (MSOT) is a biomedical imaging modality which offers a combination of molecular sensitivity, penetration depth, and resolution which are unparalleled in the field biomedical instrumentation. Nonetheless, the long acquisition time associated with MSOT and difficulties in quantifying the images it produces currently limit its possible applications. The aim of the proposed project is developing quantitative high-resolution real-time MSOT techniques for in-vivo",{"id":364,"funder":7,"programme":8,"title":365,"piName":10,"institution":366,"country":367,"year":13,"amount":10,"abstract":368},"cordis-marie-skłodowska-curie-actions-award-235907","Novel catalytic reactions involving O-H bonds","WEIZMANN INSTITUTE OF SCIENCE","IL","Our group has recently discovered novel reactions catalyzed by pyridine-based pincer complexes of ruthenium, including dehydrogenation of alcohols to form esters and H2, hydrogenation of esters to alcohols under mild conditions and an unprecedented amide synthesis: catalytic coupling of amines with alcohols, with liberation of H2 (Science, 2007, 317, 790; C&EN Aug 13, 2007, p. 10). The reactions are very efficient, proceed under neutral conditions and produce no waste. Our studies indicate that ",{"id":370,"funder":7,"programme":8,"title":371,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":372},"cordis-marie-skłodowska-curie-actions-award-234782","Three-dimensional structure of stratified turbulence","A new flow instability, known as zig-zag instability, has been revealed to be at the origin of the spontaneous formation of decoupled horizontal layers in stably stratified fluids (density decreasing along the vertical). Such layered structure is widely observed in the atmosphere and oceans. It governs the vertical transport of pollutants and chemical components and the dissipation of momentum. A critical problem is, for example, the thermal inversion in urban areas that causes the stagnation of",{"id":374,"funder":7,"programme":8,"title":375,"piName":10,"institution":314,"country":180,"year":13,"amount":10,"abstract":376},"cordis-marie-skłodowska-curie-actions-award-236658","Beyond local quantum fields: non-commutative field theory and deformed symmetries","Non-commutative quantum field theories and their associated deformed symmetries provide intriguing examples of models beyond the realm of standard local quantum field theory which attempt to introduce basic quantum features of the underlying space-time. The project will focus on a particular model of deformed space-time symmetries, the kappa-Poincare algebra, which provides the prototypical example of non-commutative field theory exhibiting a built-in cut-off (Planckian) energy scale and modifie",{"id":378,"funder":7,"programme":8,"title":379,"piName":10,"institution":314,"country":180,"year":13,"amount":10,"abstract":380},"cordis-marie-skłodowska-curie-actions-award-236337","Cinematic Representations of the Grotesque Female Body","The proposed post-doctoral research project starts from the observation that the development and application of various ‘body technologies’ such as in vitro fertilisation, cosmetic surgery and genetic engineering are accompanied by a plethora of images of incomplete, multiplied, excessively fragmented and reassembled, as well as technologically altered and grossly deformed bodies surfacing in Art Cinema and Hollywood films alike. These images stand in sharp contrast to representations that repro",{"id":382,"funder":7,"programme":8,"title":383,"piName":10,"institution":303,"country":304,"year":13,"amount":10,"abstract":384},"cordis-marie-skłodowska-curie-actions-award-221379","The Socio-Technical Evolution of Intellectual Property Online: Creating Counterfeit Culture","Recent years have seen a major shift in the nature of counterfeiting for goods such as music, video, computer games and software. Growth broadband and the increased demand for content have contributed to the exponential growth in the illegal copying and exchange. A new relationship between intellectual property (IP) owners and consumers has developed where tensions between control and access is being negotiated and, at times, resisted. Further, the piracy of digital products has become normalise",{"id":386,"funder":7,"programme":8,"title":387,"piName":10,"institution":185,"country":186,"year":13,"amount":10,"abstract":388},"cordis-marie-skłodowska-curie-actions-award-237106","Integrated Quantum Optomechanical Systems (IQOS)","Microstructures of high mechanical and optical quality are promising contenders in the race to achieve the first demonstration of quantum optical control of a “macroscopic” mechanical system. The ultimate goal in this emerging field of quantum optomechanics is to combine the concepts of cavity quantum optics with radiation pressure coupling to generate and detect quantum effects of massive mechanical systems, including the quantum ground state or even entangled quantum states of mechanical devic",{"id":390,"funder":7,"programme":8,"title":391,"piName":10,"institution":392,"country":393,"year":13,"amount":10,"abstract":394},"cordis-marie-skłodowska-curie-actions-award-220947","Spatial Heterogeneity of Resources: a mediator of large herbivore population stability?","UNIVERSITETET I OSLO","NO","The overall objective of SPHERE is to explore the role of spatial heterogeneity of resources as a mediator of large herbivore population stability in African savannas. Recent studies predict that the increased variability in rainfall that is predicted under local climate change scenarios and the resulting temporal variability in resource availability will lead to severe declines in African herbivore populations. However, new theory predicts that spatial heterogeneity of resources can act as a bu",{"id":396,"funder":7,"programme":8,"title":397,"piName":10,"institution":398,"country":110,"year":13,"amount":10,"abstract":399},"cordis-marie-skłodowska-curie-actions-award-237633","Modelling Market Interaction","UNIVERSITE D'AIX MARSEILLE","It is widely recognised that the standard notion of market equilibrium omits many aspects of how real markets function. Who sets prices, who trades with whom and how the market settles, if it does on a single price for each good are largely unanswered questions. To obtain an understanding of how markets actually function and their dynamics, we have to allow for the different degrees of rationality of market participants, learning mechanisms and the structure of the interactions between the vario",{"id":401,"funder":7,"programme":8,"title":402,"piName":10,"institution":403,"country":127,"year":13,"amount":10,"abstract":404},"cordis-marie-skłodowska-curie-actions-award-219676","Internalist vs externalist evolutionary biology: do we need a New Synthesis?","THE UNIVERSITY OF MANCHESTER","The theory of evolution is fragmented by two different views of life: the externalist and the internalist perspective. From the formulation of the theory of natural selection by Darwin, in 1859, externalist view has dominated in evolutionary thought. In the last decades, internalist perspective has recovered vigour in the light of recent empirical advances in molecular genetics. An alternative theory is emerging. The major aim of this project is to contribute to the development of a common conce",{"id":406,"funder":7,"programme":8,"title":407,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":410},"cordis-marie-skłodowska-curie-actions-award-219367","Science without Empire: Science, Medicine, Scientific networks and the Danish Halle Mission in the Danish East Indies, 1770-1845","EUROPEAN UNIVERSITY INSTITUTE","IT","The project investigates the construction of science, medicine and scientific networks in colonial India in the period ca. 1770-1845 from a new perspective: the Danish Halle Mission and the Danish East Indies. Resent research has recognised that science and medicine were not neutral elements in the colonization but were used by the colonial powers to gain control of both the inhabitants and the environment of the colonies. However, the diffusion of science and medicine was not unidirectional fro",{"id":412,"funder":7,"programme":8,"title":413,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":414},"cordis-marie-skłodowska-curie-actions-award-237018","Developing robots' social skills to support human-robot joint action execution","One major challenge in robotics research is to develop robots able to operate and help humans in everyday life. Personal robots are an emerging technology with a significant potential across broad applications (eldercare, healthcare, education, etc). However, for acting in a human world, acting for, with, or in contact of humans, we need to provide the robot with the abilities not only to act but also to interact. For humans, this capacity is named social intelligence and makes us exhibit fundam",{"id":416,"funder":7,"programme":8,"title":417,"piName":10,"institution":418,"country":162,"year":13,"amount":10,"abstract":419},"cordis-marie-skłodowska-curie-actions-award-236678","Late Holocene climate and sea ice variability in the southwestern Labrador Sea","Geological Survey of Denmark and Greenland","CLIMICE aims to reconstruct late Holocene changes in sea ice variability and regional sea surface temperatures (SST) in the Labrador Sea area using high-resolution sediment records. Information of past natural variability in climate is essential for refining and validating future climate change models and improving predictions. The records will contribute to a better understanding of the role of Arctic sea ice export by the Labrador Current in influencing large-scale North Atlantic thermohaline ",{"id":421,"funder":7,"programme":8,"title":422,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":423},"cordis-marie-skłodowska-curie-actions-award-235319","Trends and Patterns of Interethnic Parnerships and Well-being of Mixed Ethnic Children in the EU","This projects aims to conduct a cross-national analysis of interethnic partnerships in the European Union. The study focuses on partnerships between natives and immigrants because interethnic union has long been regarded as an indicator of integration. Focusing on the 27 member states of the EU, this research will explore two main themes: 1) trends and patterns of interethnic partnerships; and 2) socioeconomic well-being of offspring of interethnic unions. The study will focus on explaining simi",{"id":425,"funder":7,"programme":8,"title":426,"piName":10,"institution":427,"country":137,"year":13,"amount":10,"abstract":428},"cordis-marie-skłodowska-curie-actions-award-236511","Polynuclear manganese and manganese calcium complexes: searching for water oxidation catalysts","UPPSALA UNIVERSITET","The project deals with the synthesis and characterization of polynuclear Mn and Mn\u002FCa complexes as potential water oxidation catalysts. The “direct synthesis” approach in which zerovalent metals or metal oxides are employed as starting material will be used for the preparation of the polynuclear complexes. The isolated complexes will be identified by analytical methods (atomic absorption, CHN-analysis) and characterized by IR, UV-Vis, EPR spectroscopy, magnetochemistry, electrochemistry and sing",{"id":430,"funder":7,"programme":8,"title":431,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":432},"cordis-marie-skłodowska-curie-actions-award-236345","Processing of Mesoscopic Time-pulsed Entangled Optical fields","Quantum physics is promising to start a revolution in the way we conceive the treatment of information. Future quantum computers will be able to solve complex problems for which an efficient solution is now difficult to implement. Their construction will require an unprecedent level of accuracy in manipulating quantum systems; quantum properties of light are appealing for this project, both at a “microscopic” regime, adopting single photons, and at a “mesoscopic” regime, employing the quadrature",{"id":434,"funder":7,"programme":8,"title":435,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":436},"cordis-marie-skłodowska-curie-actions-award-235375","Atom interferometry at the Heisenberg limit using an in-cavity Bose-Einstein condensate and quantum non demolition detection","Inertial sensors using ultracold neutral atoms and atom interferometry techniques have demonstrated performances competing or even beating the more conventional light based interferometers. To further improve their sensitivity, quantum-non demolition (QND) detection schemes are presently investigated in order to engineer the initial state creating correlations between the atoms. Spin squeezed samples have been recently obtained, and it allowed to surpass the shot-noise detection limit. In this n",{"id":438,"funder":7,"programme":8,"title":439,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":440},"cordis-marie-skłodowska-curie-actions-award-237651","Understanding the role of transition metals in Alzheimer's disease on a molecular level","The aggregation of the amyloid-beta peptide (A-beta) into fibrils and successively in plaques is the main event in Alzheimer's disease. The A-beta originates from a membrane protein called amyloid-precursor protein. In healthy brain A-beta is present as soluble form and the predominant chains are formed by 40 or 42 amino acids. The oligomers of A-beta, rather then fully formed fibrils, are suspected to have nerotoxic properties. The transition metal zinc, copper, iron are present in amyloid plaq",{"id":442,"funder":7,"programme":8,"title":443,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":444},"cordis-marie-skłodowska-curie-actions-award-221515","Magneto-optics of carbon nano-allotropes","The project aims at magneto-optical spectroscopy studies of carbon nano-allotropes: graphene, individual nano-tubes and graphene nano-ribbons. The main objective of the project is to explore the new fundamental phenomena by studying the structures which are among the most promising ones for development of future nano-technologies. Understanding the properties of these systems will certainly have the impact on the effectiveness of their applications. The project consists of three specific parts. ",{"id":446,"funder":7,"programme":8,"title":447,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":448},"cordis-marie-skłodowska-curie-actions-award-235249","Toward new polymeric materials by metal-mediated controlled radical polymerization","Controlled radical polymerization has revolutionized polymer research and has already started to revolutionize the polymer industry as previously unthinkable and complex polymer architectures are becoming available. However, access to a wider variety of polymer material is limited by the inability (so far) to control the radical polymerization of nucleophilic monomers. The host team is a world leader in the understanding and application of transition metal one-electron processes (homolytic bond ",{"id":450,"funder":7,"programme":8,"title":451,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":452},"cordis-marie-skłodowska-curie-actions-award-221482","Nanosensors to monitor metal dynamics in living plant cells","Metals, such as manganese or zinc, are vital elements for plant growth and development. They are involved in many biological processes and one third of characterized enzymes are metalloproteins. Because metal excess or metal deprivation is deleterious for cells, plants have developed mechanisms to regulate the uptake, the transport and the storage of metals. Dr Thomine’s group, in Gif-sur-Yvette (France), has obtained evidence that metal compartmentalization is essential for metal homeostasis. H",{"id":454,"funder":7,"programme":8,"title":455,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":457},"cordis-marie-skłodowska-curie-actions-award-234823","The role of Prostaglandin D2 in cancer-associated inflammation","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","Cancer associated inflammation is well known to contribute to tumour progression,and pro-inflammatory mediators, including cytokines and prostaglandins, can drive malignancy. Prostaglandins are generated from arachidonic acid by the action of cyclooxygenase (COX), and include PGE2 as a major pro-inflammatory mediator, and PGD2 that has anti-inflammatory activity. While it is well known that PGE2 promotes tumourogenesis, there is little known about the role of PGD2 in cancer. Our aim is to establ",{"id":459,"funder":7,"programme":8,"title":460,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":461},"cordis-marie-skłodowska-curie-actions-award-237065","Application of directed evolution to the study of structural enzyme dynamics","We propose to study the importance of structural dynamics to enzymatic catalysis. This will utilise simplified model systems in which a variety of catalytically distinct mutants have been generated though directed evolution. This research will focus on whether changes to the conformational landscape of enzymes affect catalysis and how the structural scaffold can determine the optimum temperature for enzymatic activity. Two model systems will be used: (i) the lactate dehydrogenase family, chosen ",{"id":463,"funder":7,"programme":8,"title":464,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":465},"cordis-marie-skłodowska-curie-actions-award-235300","Simulating Coherent Control with Spectroscopic Accuracy","In recent years, impressive advances have been made in coherent control. Most current experiments rely on adaptive feedback control, which often generates optical fields too complicated to allow for mechanistic interpretation. We will use sophisticated models based on Multichannel Quantum Defect Theory (MQDT) to simulate experiments in benchmark molecules H2, NO, H2O, HCO and NO2 with spectroscopic accuracy. This will allow us to examine control mechanisms in detail and develop analytic tools fo",{"id":467,"funder":7,"programme":8,"title":468,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":469},"cordis-marie-skłodowska-curie-actions-award-220664","Melting of a pyroxenite-peridotite marble cake mantle, Ronda Massif-southern Spain: implications for the compositional heterogeneity of mantle-derived melts","The mantle is the main source of the magmas that extrude at the Earth surface and an essential goal for Earth scientists is to understand how this reservoir works and how it produces different types of melts. The isotopic variability of mantle-derived melts reflects the lithological heterogeneity of their source, but provides little information on how these heterogeneities were acquired. The Ronda peridotite (southern Spain) is a unique natural laboratory to unravel how the mantle acts during me",{"id":471,"funder":7,"programme":8,"title":472,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":473},"cordis-marie-skłodowska-curie-actions-award-237109","Study of the functional role of the distinct skin dendritic cell subsets in vivo","The skin is a fascinating tissue at the level of immune regulation. As barrier with the outside world, it is in constant contact with innocuous environmental antigens, but it is also the entrance site for pathogens. Dendritic cells (DCs) play an essential role in initiation and regulation of immune responses. Thus, skin DCs appear to mediate two seemingly incompatible functions: maintaining tolerance against harmless self and environmental antigens constantly present in the skin, while retaining",{"id":475,"funder":7,"programme":8,"title":476,"piName":10,"institution":398,"country":110,"year":13,"amount":10,"abstract":477},"cordis-marie-skłodowska-curie-actions-award-235688","Random walks on hyperbolic groups","The project lies at the confluent of different mathematical fields: probability theory, algebra, and geometry. There is a contribution of A. V. Vershik in a special Springer volume about the future of mathematics in the 21st century that points out the prospects and challenges that are comprised in the interplay of probability theory and algebra. Here random walk theory, a branch of probability theory, plays a mayor role. There are two points of view to look at the relation between probability t",{"id":479,"funder":7,"programme":8,"title":480,"piName":10,"institution":408,"country":409,"year":13,"amount":481,"abstract":482},"cordis-marie-skłodowska-curie-actions-award-235363","Age, Inequality and Social Justice. Britain and Germany since 1945","€226,974","The research project seeks to explore the relationship between structures of inequality and perceptions of social justice in the modern welfare state across two periods: the three decades of its “Golden Age” after World War II, and the still ongoing period of welfare state retrenchment since the 1970s. It focuses on the social and living conditions of old people. Despite their steadily growing number and importance the elderly still constitute a neglected group in social history. Since their fat",{"id":484,"funder":7,"programme":8,"title":485,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":486},"cordis-marie-skłodowska-curie-actions-award-221249","Single Spin Manipulation towards quantum computation","One of the schemes proposed to implement quantum computing relies on the properties of a single electron spin in a Quantum Dot (QD). Many experimental techniques have been proposed for the manipulation and the reading of the spin of electrons. Even so, reading a single electron spin remains a challenge. Recently the reading a single spin of a magnetic ion was demonstrated.  The group of Prof. H. Marriette (CNRS-CEA Grenoble) proposed a unique structure: CdTe QDs containing a Manganese (Mn) ion. ",{"id":488,"funder":7,"programme":8,"title":489,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":490},"cordis-marie-skłodowska-curie-actions-award-235226","Anonymity Enhancement for Information Society","While the ever increasing computational power together with the huge amount of individual data collected daily by many agencies is of great value for the society, they also arise an important threat to the privacy of individuals. In this scenario, protecting data privacy and anonymity of individuals have become a mainstream for research. Whereas privacy is a topic discussed everywhere, data anonymity recently established itself as an emerging area of computer science. Its goal is to produce usef",{"id":492,"funder":7,"programme":8,"title":493,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":494},"cordis-marie-skłodowska-curie-actions-award-219307","Symmetries and the constitution of objectivity in quantum physics: A study on the non-representationalist theories of knowledge","Recent years have seen a surge of research in the philosophy of physics. In particular, the conceptual and epistemological problems related to the interpretation of quantum mechanics have been reformulated within the framework of the current debate on structural realism. The proposed project presents an original approach, bordering between epistemology and theoretical physics, to address those philosophical issues. Such an approach adopts both an instrumentalist conception of theories and a cons",{"id":496,"funder":7,"programme":8,"title":497,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":498},"cordis-marie-skłodowska-curie-actions-award-221466","Nutritional ecology and seasonal colour polymorphism in a butterfly","Large colour ornaments such as bright plumage in birds or vivid wing coloration in butterflies are some of the most intriguing phenomena in the natural kingdom. However, the selective pressures and constraints involved in the evolution of these traits are in most cases poorly understood. Here we posit that evaluating the underlying nutritional demands of large colour patterns promises to provide novel insights in to the evolution of colour traits. Colour patterns can represent surprisingly large",{"id":500,"funder":7,"programme":8,"title":501,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":502},"cordis-marie-skłodowska-curie-actions-award-235147","Characterization of EWI-2wint and the mechanism behind its inhibition of HCV infection","There are more than 130 million people infected with Hepatitis C worldwide. The Hepatitis C virus (HCV) is an enveloped RNA virus targeting liver cells. HCV represents one of the most important pathogens of humans. It is still not clear how exactly viral entry proceeds. So far several receptors have been found to play a role in virus entry, among them CD81, SR-BI and Claudin-1. The recent finding of a negative regulator, EWI-2wint, further complicates the matter. This protein, which is an Ntermi",{"id":504,"funder":7,"programme":8,"title":505,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":506},"cordis-marie-skłodowska-curie-actions-award-236068","Multidimentional Modulation for Multimedia Communications","This project addresses the difficulties of designing modulation that provides robust, flexible connections for multimedia\u002Fvideo wireless communications. The main objectives of this project are two-fold: ensure reliable wireless transmission (specifically for retransmissions and relay-based communications) within the plurality of connectivity options in modern communications systems; and design novel hierarchical modulation schemes along with proposed methods to analyse their performance and enha",{"id":508,"funder":7,"programme":8,"title":509,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":510},"cordis-marie-skłodowska-curie-actions-award-237488","Towards Holographic QCD and beyond","The main goal of the proposal is to construct a holographic QCD model. Our preliminary results strongly suggest that D7-branes embedded in a 10d supergravity background based on the deformed conifold is the proper setup to study various QCD phenomena like chiral symmetry breaking, confinement etc. We also intent to find new deformed cones and the corresponding 10d backgrounds. Our second aim is to use these deformed cones for the warped D-brane inflation scenario. In particular, we would like to",{"id":512,"funder":7,"programme":8,"title":513,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":514},"cordis-marie-skłodowska-curie-actions-award-235142","Effect of ocean Acidification on Marine Invertebrates CALcification in sensitive ecosystems","Ocean pH has already declined by 0.1 units since pre-industrial times and is predicted to further decline by another 0.3 units by the end of the century as a consequence of increasing anthropogenic CO2. Reef-building corals and calcifying cold-water communities such as pteropods (molluscs), were identified as at higher risk. This project will focus on the effect of rising pCO2 on two sensitive and complementary models: Acropora millepora coral larvae and Limacina helicina pteropod. Both construc",{"id":516,"funder":7,"programme":8,"title":517,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":518},"cordis-marie-skłodowska-curie-actions-award-236240","Spinor Bose-Einstein Condensates for many-particle entanglement","Since the early days of quantum theory and even more since development of the field of quantum computation, it is well established that correlation and entanglement are fundamental in quantum mechanics and a remarkable effort is on the way to better understand these concepts, both from the theoretical and the experimental point of view. In this proposal a series of new experiments devoted to the study of quantum entanglement in a mesoscopic system are presented. All the proposed experiments will",{"id":520,"funder":7,"programme":8,"title":521,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":522},"cordis-marie-skłodowska-curie-actions-award-221059","Marine Environment and Sustainable-fisheries:  Observation-Model  in the Northern West Mediterranean Sea","Impacts of climate change and human fisheries on marine environment and resources are focused topics associated with our living environment and sustainability of economy.   To protest marine resources, we are seeking to develop 1) quantitative estimates of distributions and production rates of biota, and 2) predictive models for changes by an interdisciplinary approach integrating physical–chemical–biological–socioeconomic processes, and sensor–model development.  We are targeting the Gulf of Li",{"id":524,"funder":7,"programme":8,"title":525,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":526},"cordis-marie-skłodowska-curie-actions-award-237644","Voltage and calcium dynamics and synaptic transmission within neuronal microcircuits in the vestibular cerebellum","A fundamental goal of neuroscience is to understand how neurons communicate and encode information. Information transfer between neurons is classically thought to be mediated through rapid all-or-none membrane potential changes, called action potentials (APs), which lead to presynaptic calcium entry and neurotransmitter release. Recently, however, analog transmission has been detected through passive propagation of subthreshold depolarization down axons. Dendrites too exhibit active and passive ",{"id":528,"funder":7,"programme":8,"title":529,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":530},"cordis-marie-skłodowska-curie-actions-award-235552","Ultra-high resolution imaging of GluR1 trafficking in neuronal spines","The spatial and temporal regulation in the composition of the postsynaptic membrane of synapses participates to the different forms of synaptic plasticity that trigger the cellular processes of memory formation, consolidation, and retrieval. Neurotransmitter receptors move rapidly in and out of synapses by lateral diffusion. This mobility is crucial to control the number of receptors present at a given synapse. AMPA subtype glutamate receptors mediate most excitatory transmission in the brain. T",{"id":532,"funder":7,"programme":8,"title":533,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":534},"cordis-marie-skłodowska-curie-actions-award-235878","Dark Matter and Stars in the Dark Ages","The possibility that the first stars in the universe may be powered by dark matter annihilation rather than nuclear fusion has been recently proposed in the literature. This intriguing phenomenology defines a new field, in which particle dark matter properties affect the characteristics of astrophysical populations in the young universe. In DAMiDA we propose a thorough approach to the problem: stellar evolution in the presence of dark matter annihilation, the survival of these stars through the ",{"id":536,"funder":7,"programme":8,"title":537,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":540},"cordis-marie-skłodowska-curie-actions-award-234849","The SRA domain: a connection between DNA methylation and histone modifications within the epigenetic code? The Arabidopsis VIM family","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","ES","Heterochromatin in both mammals and plants is associated with methylation of cytosines within the DNA sequence. While DNA methylation is widespread in plants, fungi, and animals, it has been curiously lost in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Caenorhabditis elegans, and Drosophila. However, the methylation system in Arabidopsis is very similar to that in mammals, showing that DNA methylation is highly conserved, and that Arabidopsis is an excellent model system to study it. DN",{"id":542,"funder":7,"programme":8,"title":543,"piName":10,"institution":544,"country":409,"year":13,"amount":10,"abstract":545},"cordis-marie-skłodowska-curie-actions-award-236961","Developing a 4000-year East African fire history from the Kilimanjaro ice core","CONSIGLIO NAZIONALE DELLE RICERCHE","Tropical savanna fires currently comprise approximately two thirds of the global fire budget, making these fires a dominant factor in global carbon emissions, yet little is known how fires have varied through time. This project aims to create a fire history of the East African savanna region over the past 4000 years through the direct determination of levoglucosan in the Kilimanjaro ice core (3º04’S; 37º21’E; 5893 masl, 49 m depth). Levoglucosan is an atmospherically stable molecular tracer of b",{"id":547,"funder":7,"programme":8,"title":548,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":549},"cordis-marie-skłodowska-curie-actions-award-220970","Low energy physics from background independent quantum gravity","Quantum gravity is still one of the major open problems in fundamental physics. One of the best developed of the current approaches to quantum gravity is loop quantum gravity (LQG). The main open problem within LQG is to derive the low-energy approximation starting from the basic nonperturbative formalism. Aim of this project is to address such problem, and investigate the low energy limit of LQG. This is important for two reasons, which represent the long term objectives of this research: 1. To",{"id":551,"funder":7,"programme":8,"title":552,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":553},"cordis-marie-skłodowska-curie-actions-award-235088","The process of professionalization in European science, 1789-1850","The modern science was born in Europe at the beginning of the seventeenth century, but it was not until the middle of the nineteenth century that the scientific research became “professionalized” as we know it today. Such a process of “professionalization” was a milestone in the development of the European intellectual heritage and made Europe the world leader in the production of knowledge. Its comprehension might offer new hints and suggestions for drawing the future of Europe as leading the g",{"id":555,"funder":7,"programme":8,"title":556,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":557},"cordis-marie-skłodowska-curie-actions-award-235741","Towards a comprehensive mathematical description of the Dynamics of Nonlinear Networks. Applications in System Biology","A strong demand has been recently expressed in many disciplines of the European scientific area for the interdisciplinary development of modelling approaches to complex systems. A system is said to be complex when the knowledge of every individual is not enough to apprehend its global behaviour, and the effects of collective interactions need to be incorporated. Modelling approaches consist in establishing models and in studying their behaviours by various techniques. Mathematical techniques off",{"id":559,"funder":7,"programme":8,"title":560,"piName":10,"institution":408,"country":409,"year":13,"amount":481,"abstract":561},"cordis-marie-skłodowska-curie-actions-award-237546","Public Opinion Trends and Policy-Making in the European Union","The question of how the EU institutions can better connect with Europe's citizens is a central concern for European and national policy-makers. Measuring the degree of responsiveness of European institutions to the demands of the citizens is of vital importance because it helps to assess how successful the EU is in meeting the needs and expectations of citizens. The goal of this research is to quantitatively measure the responsiveness that is to be found between public demands and policy supply.",{"id":563,"funder":7,"programme":8,"title":564,"piName":10,"institution":403,"country":127,"year":13,"amount":10,"abstract":565},"cordis-marie-skłodowska-curie-actions-award-221766","The Space of Crisis: Towards a Critical Geography of Complex Humanitarian Emergencies","This research project seeks to develop a radical geographical critique of contemporary humanitarian emergencies within the context of contemporary globalisation. It seeks to do so via an explicitly theoretical approach that is rooted in historical geographical materialism and critical theory, and in theories of the production of space in particular.  The project’s principal objective is to elaborate a theoretical platform for the analysis of these crises as explicitly geographical phenomena, in ",{"id":567,"funder":7,"programme":8,"title":568,"piName":10,"institution":403,"country":127,"year":13,"amount":10,"abstract":569},"cordis-marie-skłodowska-curie-actions-award-219588","LINKING RINGS INTO COMPLEX STRUCTURES","The project is to link chemically controlled nanoobjects into new types of material. Specifically, a class of molecular magnet called antiferromagnetic rings can be functionalised such that through chemistry we can produce arrays of such rings. Initially we will target dimeric structures, where two such rings will be linked through a switchable group. Such structures have been proposed as possible two-Qubit quantum gates for quantum information processing. In the latter part of the project we wi",{"id":571,"funder":7,"programme":8,"title":572,"piName":10,"institution":392,"country":393,"year":13,"amount":10,"abstract":573},"cordis-marie-skłodowska-curie-actions-award-237089","Laboratory earthquakes: dynamic shear cracks in heterogeneous frictional interfaces","The main objective of the proposal is to expose an outstanding young experimental physicist to multidisciplinary research on earthquake dynamics. Dr. Julien Scheibert who is already an expert in friction and fracture dynamics will perform original research and receive training at the Norwegian Centre of Excellence, “Physics of Geological Processes” (PGP) at the University of Oslo. By working with geologists and physicists with a proven record of cross disciplinary research Dr. Scheibert will bro",{"id":575,"funder":7,"programme":8,"title":576,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":577},"cordis-marie-skłodowska-curie-actions-award-236379","Cycles of Political Violence A Comparative Historical Political-Sociology Analysis of Italy and Northern Ireland","This research project examines how political violence unfolds, develops and demises by combining knowledge coming from three major disciplines: history, political science and sociology. Analytically, it explores how the complex interactions between the social, political, and cultural environment and the internal dynamics within social movements affect cycles of political violence. At the empirical level, it systematically examines two distinct cases of political violence: the ‘socio-revolutionar",{"id":579,"funder":7,"programme":8,"title":580,"piName":10,"institution":403,"country":127,"year":13,"amount":10,"abstract":581},"cordis-marie-skłodowska-curie-actions-award-235662","Functional characterization of a novel rheumatoid arthritis susceptibility locus on chromosome 6q","Rheumatoid arthritis (RA) is the commonest inflammatory disease of synovial joints. Approximately 50% of genetic susceptibility to RA is accounted for by the HLA-DRB1 gene together with the PTPN22 gene. A whole genome association (WGA) scan recently carried out by the Wellcome Trust Case Control Consortium (WTCCC) and subsequent validation studies have confirmed that an additional susceptibility locus maps to an inter-genic region of 6q23, near the TNFAIP3 gene. This is a strong candidate RA sus",{"id":583,"funder":7,"programme":8,"title":584,"piName":10,"institution":544,"country":409,"year":13,"amount":10,"abstract":585},"cordis-marie-skłodowska-curie-actions-award-235607","An assessment of VOC and ozone fluxes in crop plantations from the leaf to the ecosystem level. Relationships with the plant physiology and implications for air quality","Citrus plants are largely grown and economically valuable crops in densely inhabited and polluted Mediterranean areas. Citrus species produce and emit VOC (Volatile Organic Compounds) which enter gas-phase reactions leading to formation of dangerous levels of atmospheric ozone especially in the presence of anthropogenic pollutants. On the other hand, biogenic VOC destroy ozone at leaf level enhancing plant protection against the pollutant. CITROVOC is keyed at understanding the dual role of VOC ",{"id":587,"funder":7,"programme":8,"title":588,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":589},"cordis-marie-skłodowska-curie-actions-award-237417","Evolving Phenotypic plasticity and Plant Invasiveness: An inter-disciplinary approach","Biodiversity is changing due to global climate change and local drivers such as the introduction of invasive species, which are considered one of the greatest threats to natural ecosystems. Despite increasing impacts, little is known about the evolutionary mechanisms that lead to invasiveness in introduced species. It is thought that the greater the breadth of environmental conditions across which a species can maintain fitness, the greater the likelihood of being invasive. A major way that plan",{"id":591,"funder":7,"programme":8,"title":592,"piName":10,"institution":392,"country":393,"year":13,"amount":10,"abstract":593},"cordis-marie-skłodowska-curie-actions-award-235237","Oxygen Activation in Ribonucleotide Reductase and Multicopper Oxidases Proteins","Boundaries among biological, chemical and physical domains are nowadays fading, and the complex phenomena observed in Nature as well as in artificial systems can only be tackled from a broader\u002Finterdisciplinary perspective. In this context, the biological activation of the molecular oxygen is a fascinating and yet complex process. The ability to store, transport and utilize this simple molecule gated evolution of life in our planet and led to growth and selection of a variety of organisms. Compl",{"id":595,"funder":7,"programme":8,"title":596,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":597},"cordis-marie-skłodowska-curie-actions-award-235569","A two-photon survey of the plasticity of the neocortical microcircuit: searching for plasticity hotspots","The cortex has been described to display synaptic plasticity, which is determinant for the function of cortical microcircuits. Although there is a large literature on neocortical plasticity, most of the experiments addressed the connections of pyramidal cells located in particular cortical layers, so the majority of intracortical connections are yet unexplored with respect to their plasticity. Moreover, these studies are contradictory in that apparently synaptic plasticity rules like spike-timin",{"id":599,"funder":7,"programme":8,"title":600,"piName":10,"institution":544,"country":409,"year":13,"amount":10,"abstract":601},"cordis-marie-skłodowska-curie-actions-award-235386","Interaction between the Gas DiffusionLayer and the Gas Flow Channel of polymer electrolyte fuel cell","Reaching high and stable efficiency with a Polymer Exchange Membrane Fuel Cell (PEMFC) during unsteady load operations is a delicate task because the transport of product water by the electrochemical reaction has to be precisely managed. Two fuel cell components and their mutual interaction play a key role in the water management: the Gas Diffusion Layer (GDL), the support of the electrode, and the Gas Flow Channel (GFC) on the cathode side ensuring gas distribution over the electrode active are",{"id":603,"funder":7,"programme":8,"title":604,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":605},"cordis-marie-skłodowska-curie-actions-award-235934","Attention and consciousness in the brain","Most of the information that reaches our senses is unconsciously processed, affecting our behaviour but out of voluntary control. Only a small portion of our environment gains conscious awareness, shaping our “perception of the word”. Attention has been proposed as the mechanism that selects relevant information, prioritizing its arrival to a conscious state. Although the details are to be worked out, the orienting of attention seems to correlate with activity in large-scale brain networks. Whet",{"id":607,"funder":7,"programme":8,"title":608,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":609},"cordis-marie-skłodowska-curie-actions-award-220243","The Effects of Precarious Work on Family Life in Europe","This project investigates the effects of precarious work on family life in Europe. So far research on precarious work has mainly focused on effects on the labour market itself. However, with an increasing fragmentation of work histories, we have to expand our focus beyond the labour market and analyse the effects of non-traditional work forms on the lives of individuals and their families. Traditional assumptions about the separation of work life and private life are no longer feasible since wor",{"id":611,"funder":7,"programme":8,"title":612,"piName":10,"institution":427,"country":137,"year":13,"amount":10,"abstract":613},"cordis-marie-skłodowska-curie-actions-award-235996","Protein signalling pathways elucidated via novel correlation analysis of molecular dynamics simulations","Signal transduction enables biological cells to respond to external stimuli such as light, odours, hormones, or growth factors. Signalling is involved in numerous biological processes and dysfunction of signalling has been associated to severe conditions such as cancer or Alzheimer’s disease. Whereas the knowledge of signal transduction on the cellular level has seen impressive progress within the last years, the molecular mechanisms involved in signalling remain mostly unknown. Intra-protein si",{"id":615,"funder":7,"programme":8,"title":616,"piName":10,"institution":392,"country":393,"year":13,"amount":10,"abstract":617},"cordis-marie-skłodowska-curie-actions-award-236549","Ecological and evolutionary dynamics of juvenescent marine populations: a comparative study of the European hake in the Atlantic and the Mediterranean","Much evidence shows that fishing is driving evolutionary changes in the life traits of marine fish populations. Fishing does not only decrease the abundance of populations, but also changes the genetic composition of their individuals with negative impacts on the recovery capacity, and on the functioning of the ecosystems. Moreover, fishing is removing the largest individuals from many stocks leading the fish populations mainly supported by young age classes (juvenescent populations). However, t",{"id":619,"funder":7,"programme":8,"title":620,"piName":10,"institution":621,"country":622,"year":13,"amount":10,"abstract":623},"cordis-marie-skłodowska-curie-actions-award-236695","IDENTIFYING INHIBITORS OF PROX1 IN COLORECTAL CANCER","HELSINGIN YLIOPISTO","FI","Colorectal cancer (CRC) is one of the leading causes of cancer related mortality in the developed countries. Interestingly, the host laboratory has recently discovered that the homeobox transcription factor PROX1 is overexpressed in the vast majority of human CRCs as well as in mouse models of intestinal cancer with abnormal beta-catenin\u002FTCF signaling. Furthermore, they provided evidence that PROX1 is regulated by the high concentration of beta-catenin and this regulation seems to be tissue spec",{"id":625,"funder":7,"programme":8,"title":626,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":627},"cordis-marie-skłodowska-curie-actions-award-221685","Impact of the ionic channel and NOS1AP SNPs on the risk of cardiac events in Long QT Syndrome","Cardiovascular disease is a leading cause of death worldwide. A number of these deaths are due to severe disturbances in cardiac rhythm (ventricular tachycardia or fibrillation) that lead to a fatal cardiac arrhythmia or sudden cardiac death. Ventricular tachycardia or fibrillation can occur during exercise or excitement, and has been associated with an underlying disorder called Long QT Syndrome (LQTS). The clinical course of LQTS is variable, some patients remain asymptomatic while others deve",{"id":629,"funder":7,"programme":8,"title":630,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":631},"cordis-marie-skłodowska-curie-actions-award-236924","Molecular mechanisms involved in the IGF-1R signalling setting of the somatotropic axis","This proposal aims to understand molecular mechanisms involved in the induction and persistence of the somatotropic function decrease observed in mice with diminished IGF-I signalling. This alteration could be induced by a specific heterozygous IGF-1R invalidation in mice brain, and in wild type mice, by a nutrient restriction during the first two weeks of life. Previous results obtained in these both models indicate that diminished IGF-I signalling first decreases hypothalamic GHRH gene express",{"id":633,"funder":7,"programme":8,"title":634,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":635},"cordis-marie-skłodowska-curie-actions-award-221407","Global regulation in Mycobacterium: Role of Lsr2","This proposal aims at understanding the role of Lsr2 in the global regulation of the mycobacterial cell wall homeostasis, a critical attribute of their virulence. Mycobacteria are Gram-positive bacteria that are involved in a number of human (tuberculosis, leprosy, Buruli ulcer) and animal diseases (Johne’s disease in ruminanst, fish tuberculosis in aquaculture), in both developing and developed countries. The lsr2 gene in conserved in all mycobacteria sequenced thus far and recent data indicate",{"id":637,"funder":7,"programme":8,"title":638,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":639},"cordis-marie-skłodowska-curie-actions-award-237665","Fictions and arguments of Plato’s dialogues","The project examines the modalities, place, status, and roles of fictional elements in Platonic dialogues. The Applicant proposes an inquiry into the nature of Platonic fiction based on a selection of characteristic themes offered as fictional by characters in various Plato’s dialogues. The analysis will aim at a better understanding of the modes of fictionality Plato used, and, as a result, of the Platonic dialogue as a whole. The work hypothesis to be examined is: (1) Plato used various false ",{"id":641,"funder":7,"programme":8,"title":642,"piName":10,"institution":156,"country":110,"year":13,"amount":10,"abstract":643},"cordis-marie-skłodowska-curie-actions-award-236827","Effective Field Theory for Loop Quantum Gravity","The objective of this research project is to develop the Loop approach to Quantum Gravity and identify the regime where the dynamics of the theory can be described in terms of a perturbative quantum theory of gravitons on flat space. The project is to be articulated into three main levels of work: (a) investigate the dual picture of quantum geometry proper of Loop Quantum Gravity, identifying semiclassical states peaked on simplicial geometries; (b) compute large scale correlations for spin foam",{"id":645,"funder":7,"programme":8,"title":646,"piName":10,"institution":456,"country":110,"year":13,"amount":10,"abstract":647},"cordis-marie-skłodowska-curie-actions-award-237028","Vascular inflammation and atherosclerosis","Atherosclerosis is an immunoinflammatory disease of the arterial wall that carries an important socio-economic burden. Atherosclerotic lesions contain activated T cells and specific cytokines along with immunoglobulins. Several studies have shown that atherosclerotic patients develop a perturbed inflammation toward arterial proteins suggesting that autoimmune processes may play a role in atherosclerosis progression. Moreover, patients with aggressive inflammatory diseases such as autoimmune dise",{"id":649,"funder":7,"programme":8,"title":650,"piName":10,"institution":621,"country":622,"year":13,"amount":10,"abstract":651},"cordis-marie-skłodowska-curie-actions-award-237531","Improvement of Technical Capabilities for Research and Development (R&D) Related to Separation, Determination and Preliminary Production of different Rare Earth Elements","Currently, there is a growing demand for rare earth elements (REEs) production technology to satisfy many characteristics economically and industrial activities. In this respect, expanding needs are therefore requested for production of lanthanides, which is considered as one of our primary industrial objectives. In general, the proposed project is oriented to gather the new idea during the mutually beneficial research cooperation in the field of inter and intra separation as well as production ",{"id":653,"funder":7,"programme":8,"title":654,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":655},"cordis-marie-skłodowska-curie-actions-award-237383","Catalytic C-H activation-Initiated Tandem Reactions: Devise, Study and Application to natural renewable molecules","On the one hand, it is now assumed that in the near future the starting materials in chemistry have to come from renewable feedstock and not only from petroleum cracking. On the other hand, the stability of the chemical bonds in saturated hydrocarbons makes them generally unreactive, and a large variety of hydrocarbons constitute a large lowcost feedstock misused, which is treated as fuel or waste. But the invention of processes in which carbon–hydrogen (C–H) bonds in hydrocarbons can be activat",{"id":657,"funder":7,"programme":8,"title":658,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":659},"cordis-marie-skłodowska-curie-actions-award-219475","The Limits of Peaceful Co-existence: Jewish-Arab Relations, Urban Space and State Violence in Palestinian-Israeli Mixed Towns, 1882 to the Present","As part of a larger project on ethnic relations in Mediterranean Cities, this research examines how urban space, violent conflict and national identities have been both represented and produced in ethnically mixed cities in Israel\u002FPalestine. Against the background of a century-long conflict between the Jewish and Palestinian national movements, this project studies the relations between opposing “projects of nativization” and community building efforts in a contested urban setting. While most sc",{"id":661,"funder":7,"programme":8,"title":662,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":663},"cordis-marie-skłodowska-curie-actions-award-235233","Reconfiguration of Catholic women’s league militancy in France and in Italy (1919-1939)","This comparative project about catholic women in Italy and in France during the Interwar period (1920-1939) will benefit from the EUI international perspective and structure. Having just completed a comparative study of two important mass organizations of conservative Catholic women in early 20th century France and Italy, namely the Ligue patriotique des Françaises and the Unione fra le donne cattoliche d’Italia, I would like to turn my attention to the vital question of the reconfiguration of F",{"id":665,"funder":7,"programme":8,"title":666,"piName":10,"institution":408,"country":409,"year":13,"amount":10,"abstract":667},"cordis-marie-skłodowska-curie-actions-award-235186","Between Penal Revolution and National Resistances. The Influence of the Napoleonic Judicial Model in Continental Europe (1808-1814)","My research project aims to define the principles of the Napoleon judicial model and to evaluate their influence in the European regions annexed by the French Empire: Italy, Belgium, the Netherlands, and the Rhineland. By using a comparative approach, I intend to reexamine the image of imperial justice, which has been conceived as an invariable mass of granite, universal and inflexible, founded on an utilitarian, centralized and authoritarian application of law. Such a sanctification of imperial",{"id":669,"funder":7,"programme":8,"title":670,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":671},"cordis-marie-skłodowska-curie-actions-award-219621","The origin of evolutionary novelties: regulation of Hoxd genes and the evolutionary transition from fish fins to tetrapod limbs","The fossil record suggests that fish fins suffered sequential transformations, giving rise to limbs close to the origin of tetrapods. However, the molecular mechanisms that underlie this evolutionary transition remain unclear. Interestingly, Hoxd genes exhibit a single phase of expression during zebrafish fin development but, in contrast, are expressed in two independent phases during mice limb development. The second phase is essential for digit development, the main innovation of the tetrapod ",{"id":673,"funder":7,"programme":8,"title":674,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":675},"cordis-marie-skłodowska-curie-actions-award-236079","Complexity, stability and chaos in marine model ecosystems for present day and global warming conditions","The relationships between complexity, stability and chaos in ecosystem food webs are not clearly understood in the global marine environment. We propose to explore these connections using a global marine ecosystem model in which the level of species diversity is an emergent property. We will map globally indices of: phytoplankton diversity, food web connectance, complexity, stability, chaotic behaviour, and productivity. Complexity is the product of species diversity and food web connectance. St",{"id":677,"funder":7,"programme":8,"title":678,"piName":10,"institution":679,"country":180,"year":13,"amount":10,"abstract":680},"cordis-marie-skłodowska-curie-actions-award-236020","Modeling reciprocity in games","UNIVERSITEIT MAASTRICHT","Reciprocity plays an important role in socio-economic interactions as recognized by social scientists in all fields. However, there is no interdisciplinary consensus over the definitions of scientific terms, models, and experimental practices to study it. This project will be an attempt to bring together the best findings and techniques from different fields and create a framework that would allow the possibility to systematically study reciprocal behavior. In the first part of the project the g",{"id":682,"funder":7,"programme":8,"title":683,"piName":10,"institution":679,"country":180,"year":13,"amount":10,"abstract":684},"cordis-marie-skłodowska-curie-actions-award-221187","The Multisensory Human Brain - Solving the debate on direct and indirect pathways","The fellowship aims to elucidate at which processing stage the different sensory systems (vision, audition) of the human brain interact, and whether this stage depends on what kind of information is integrated, and why. The project proposal starts from very recent data suggesting that our sensory systems are not nearly as independent as traditionally thought. Therefore, it will provide building blocks for a novel theoretical frame for multisensory integration and perception in general. Furthermo",{"id":686,"funder":7,"programme":8,"title":687,"piName":10,"institution":679,"country":180,"year":13,"amount":10,"abstract":688},"cordis-marie-skłodowska-curie-actions-award-236069","Improving coherence between private law and competition law","Insufficient coherence exists between the proposals to harmonize the law of contracts\u002Fobligations and EC competition law. Although the Commission has supported both the initiatives to create principles of contract law and a Common Frame of Reference on the one hand and rules concerning damages for antitrust infringements on the other hand, their mutual influences are limited. This led e.g. to the result that the Draft Common Frame of Reference contains rules that are difficult to reconcile with ",{"id":690,"funder":7,"programme":8,"title":691,"piName":10,"institution":679,"country":180,"year":13,"amount":10,"abstract":692},"cordis-marie-skłodowska-curie-actions-award-237614","Psychological game theory and Bayesian rationality","The main objective of this project is to study the epistemic conditions for equilibria in psychological games. This is a natural way to go, since a psychological game incorporates beliefs into the individual’s payoff function. The epistemic analysis in the literature is divided in two big branches: the type space approach introduced by Harsanyi (1967)-68 and the Bayesian state space approach introduced by Aumann (1976). The theory in psychological games employs tools only from the first approach",{"id":694,"funder":7,"programme":8,"title":695,"piName":10,"institution":696,"country":162,"year":13,"amount":10,"abstract":697},"cordis-marie-skłodowska-curie-actions-award-236417","EIT based addressing of individual ions in a microtrap","AARHUS UNIVERSITET","Recent amazing experiments with trapped ions have demonstrated the feasibility of ion based quantum computing. At the same time, these prove of principle experiments have allowed us to analyze the experimental limitations on the fidelity of each quantum operation, on its speed, as well as on the storage time of the quantum memory. Moreover, since a practical quantum computer should operate with much more qubits and more complicated algorithms, requiring more operations, these experiments have al",{"id":699,"funder":7,"programme":8,"title":700,"piName":10,"institution":696,"country":162,"year":13,"amount":10,"abstract":701},"cordis-marie-skłodowska-curie-actions-award-219293","Insulated Programmable Carbon Nanotube Nanowires with DNA Recognition for Nanoelectronics Applications","The proposed project will develop a novel programmable ultrathin insulating sheet wrapped carbon nanotube nanowire with DNA recognition ability. The proposed work will for the first time create SWCNT insulated by ultrathin insulating layer. ssDNA recognition element will be attached to the coated\u002Finsulated SWCNT. Since DNA is one of the most programmable molecules, such dual-type of ultrathin layer insulated SWCNT-DNA assembly is unique and will have profound effect on development of nanoelectro",{"id":703,"funder":7,"programme":8,"title":704,"piName":10,"institution":679,"country":180,"year":13,"amount":10,"abstract":705},"cordis-marie-skłodowska-curie-actions-award-235973","Learning Across Games","In this proposal we aim to study the twin questions of a) how agents categorize decision problems (and in particular games) according to their similarity and b) how this categorization affects standard predictions in Game Theory. The most important contribution to the literature is that we endogenize the question of categorization, assuming that categorizations can be learned. Existing literature is characterized by making sometimes ad hoc assumptions on categorizations. Initial results have alr",{"id":707,"funder":7,"programme":8,"title":708,"piName":10,"institution":709,"country":137,"year":13,"amount":10,"abstract":710},"cordis-marie-skłodowska-curie-actions-award-237136","SUSTAINABLE DESIGN OF MANUFACTURING SYSTEMS","KUNGLIGA TEKNISKA HOEGSKOLAN","The contribution of SUSTAIN-MS to EU manufacturing added value refers to environmental sustainability issues addressed through more efficient model-based design of manufacturing systems that will yield more efficient production by reduced waste and energy use. The way to achieve this is to apply machining processes with advanced cooling-lubrication and to adapt machine tools to such a stage that the process vibrations are decreased. In support of SUSTAIN-MS design efforts the following sustainab",{"id":712,"funder":7,"programme":8,"title":713,"piName":10,"institution":714,"country":127,"year":13,"amount":10,"abstract":715},"cordis-marie-skłodowska-curie-actions-award-235636","The Ecology and Immunogenetics of Parasites in Invasive Species","CARDIFF UNIVERSITY","Invasive species are a major threat to biodiversity and human health because they often undergo unregulated population growth, putatively because they have escaped their predators; the enemy release hypothesis. However, parasites are also ‘enemies’ and recent work has shown that invasive species lack a full parasite community. So we ask, “does the reduced parasite community contribute to invasion success?” The first step is to undertake rigorous, replicated experiments that will empirically comp",{"id":717,"funder":7,"programme":8,"title":718,"piName":10,"institution":714,"country":127,"year":13,"amount":10,"abstract":719},"cordis-marie-skłodowska-curie-actions-award-221689","Defining the mechanisms by which platelets regulate neutrophil extracellular traps in sepsis","Despite treatment advances, sepsis kills an estimated 150,000 in the EU annually. Lipopolysaccharide (LPS), neutrophils and platelets all participate in the pathogenesis of severe sepsis, but the inter-relationships between these players are poorly understood. Recently, we demonstrated that activation of neutrophils by platelets is necessary to defend against bacterial infection (Clark et al, Nat Med 2007). In response to endotoxaemia or bacteraemia, neutrophils lodged primarily in lung capillar",{"id":721,"funder":7,"programme":8,"title":722,"piName":10,"institution":723,"country":304,"year":13,"amount":10,"abstract":724},"cordis-marie-skłodowska-curie-actions-award-236618","The role of A20 in dendritic cells and mast cells in the allergic immune response","VIB VZW","Asthma is a chronic inflammatory airway disease in which the transcription factor NF-kB plays a crucial role. NF-kB controls the activation of mast cells and dendritic cells (DC) that contribute to disease pathogenesis. Activation of NF-kB is tightly regulated by ubiquitination and deubiquitination of signaling intermediates. Studies in the host laboratory identified several deubiquitinating enzymes like A20 (also known as TNFaip3) and its binding partners to set the tone for NF-kB activation. A",{"id":726,"funder":7,"programme":8,"title":727,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":729},"cordis-marie-skłodowska-curie-actions-award-237547","Understanding Hedgehog signalling in breast cancer and mammary gland stem cells using tissue specific expression of Gli1 the main effector of the Hedgehog pathway","KAROLINSKA INSTITUTET","Only a subset of tumour cells is capable of giving rise to new tumours. These so called “tumour stem-cells” are functionally similar to adult stem cells and have been identified in tumours of several tissues. Whether transformation of adult stem cells into tumour stem cells is the event leading to the disease is not clear. Alternatively, tumours could arise from the population of committed progenitors, which have de novo acquired self-renewal properties. The aim of the proposed project is to inv",{"id":731,"funder":7,"programme":8,"title":732,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":733},"cordis-marie-skłodowska-curie-actions-award-237040","Development of a new high throughput automated imaging system to carry out drug sensitivity measurements on primary leukemia\u002Flymphoma cells to assist individualized assay guided therapy","The aim of the project is to build a new robust prototype of a high throughput automated imaging system that can be used in routine clinical lab environment for gathering data on drug sensitivity patterns of primary leukemia\u002Flymphoma cells. The device will assist individualized assay guided therapy. The laboratory at the host institute has recently created a new microculture system that allows viability testing of drug treated primary tumor cells. The present system is exclusively based on comme",{"id":735,"funder":7,"programme":8,"title":736,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":737},"cordis-marie-skłodowska-curie-actions-award-220044","Defense mechanisms of innate immunity against influenza virus","Influenza virus represents a major worldwide health problem and influenza pandemics are amongst the deadliest disease events for humans and many animal species. Although it is known that the innate immune system represents the first line of defense against the virus, the mechanism by which it is activated in response to influenza virus remains to be elucidated. This project aims to study the interaction between the innate immune system, particularly the complement system, and influenza virus. Fo",{"id":739,"funder":7,"programme":8,"title":740,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":741},"cordis-marie-skłodowska-curie-actions-award-221576","The role of natural killer T cells in the early stages of the herpes simplex virus infection in skin","The aim of this project is to examine how the local skin microenvironment influences the generation of antiviral immune responses following herpes simplex virus type 2 (HSV-2) infection. Genital herpes, caused primarily by HSV-2, has a worldwide prevalence and is the leading cause of genital ulcers. An increasing number of clinical and epidemiological studies indicate that a recent genital HSV-2 infection increases the risk of HIV acquisition and transmission by up to 3-fold. Therefore, further ",{"id":743,"funder":7,"programme":8,"title":744,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":745},"cordis-marie-skłodowska-curie-actions-award-219333","Defining the transcription factors code directing sensory lineage diversification and connectivity","How is the enormous cellular complexity that characterizes the vertebrate organism arising? Cell diversification depends on the coordinated deployment of multiple programs of cell commitment. One fundamental question is how a discrete number of transcriptional programs combine to produce different cell types. This research aims to address the principles of how cellular diversity is created in the sensory nervous system. Specific objectives: #1:Defining the role of Cux1\u002F2 transcription factors in",{"id":747,"funder":7,"programme":8,"title":748,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":749},"cordis-marie-skłodowska-curie-actions-award-220754","Investigating Neutrinos in Cosmology and Astrophysics","We propose to explore the role of neutrinos in cosmology and astrophysics via theoretical investigations and the development of numerical and computational tools. In the first case, we shall investigate further the phenomenology related to the cosmological neutrino mass and energy density determination, exploiting the forthcoming data from the Planck ESA satellite and other cosmological surveys and probes.  Particular attention will be devoted to the cosmological impact of new physics in the neu",{"id":751,"funder":7,"programme":8,"title":752,"piName":10,"institution":753,"country":539,"year":13,"amount":10,"abstract":754},"cordis-marie-skłodowska-curie-actions-award-237225","New methods to evaluate the impact of single point protein mutation on human health","UNIVERSITAT DE LES ILLES BALEARS","The Single Nucleotide Polymorphisms (SNPs) are the main cause of the sequence variability in human. For this reason, the prediction of the impact of SNPs is one of the most challenging problems in computational biology and bioinformatics. The increasing growth of the genome-scale studies is providing a large amounts of SNP data, allowing the application of rigorous statistical approaches for predicting whether a given single point mutation has an effect on human health. In spite of the scientifi",{"id":756,"funder":7,"programme":8,"title":757,"piName":10,"institution":758,"country":759,"year":13,"amount":10,"abstract":760},"cordis-marie-skłodowska-curie-actions-award-220108","Geometrical aspects of spin and vortex dynamics in electromagnetic and matter waves","UNIVERSITY OF GALWAY","IE","The project is intended to reveal a unifying nature and fundamental geometrical features of the spin and vortex dynamics of classical electromagnetic and quantum-mechanical matter waves. The Berry phase, Magnus effect, and spin-Hall effect are attracting ever-increasing interest of scientists because of their potential applications in nano-physics, spintronics, quantum computing, etc. Simultaneously, the modern optics (including nano-optics, photonics, and plasmonics) offers unique possibilities",{"id":762,"funder":7,"programme":8,"title":763,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":764},"cordis-marie-skłodowska-curie-actions-award-236059","Improvement of SQGs through the incorporation of chronic exposure-effect model","Sediments are extremely important to the food web and serve as the ultimate repository and source of most of the contaminants, including metals. For this reason, it is appropriate that regulatory attention addresses the ecological risks that these sediment contaminants might pose. So much so that, the need to understand the impacts of contaminated sediments on aquatic environmental quality is implicit in the text of the Water Framework Directive (2000\u002F60\u002FEC), and in the Directive on Environmenta",{"id":766,"funder":7,"programme":8,"title":767,"piName":10,"institution":758,"country":759,"year":13,"amount":10,"abstract":768},"cordis-marie-skłodowska-curie-actions-award-220665","Engineering aspects and mechanisms of redox-stratified membrane bioreactors for completely autotrophic nitrogen removal from wastewater","Novel redox-stratified membrane bioreactors (RSMBRs) will be developed for completely autotrophic nitrogen removal from wastewater. This technology is based on simultaneous nitritation and anaerobic ammonium oxidization (anammox) occurring in redox-stratified counter-diffusion biofilms grown on the surface of gas-permeable membrane. With precise control of the oxygen supply flux, the growth of nitrite oxidizing bacteria will be inhibited. A stable redox-stratified counter-diffusion biofilm with ",{"id":770,"funder":7,"programme":8,"title":771,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":772},"cordis-marie-skłodowska-curie-actions-award-219680","Influence of the in utero environment on the risk of allergy development for the child","Today allergies are a major public health problem. Previous cross-sectional studies have found that children growing up with an anthroposophic lifestyle have a lower prevalence of IgE-mediated allergic diseases. This observation strengthens the hypothesis on importance of interaction between environment and our immune system during early childhood regarding allergy. The focus of this project is to assess if lifestyle and allergy states of the parents can cause differences in the in utero environ",{"id":774,"funder":7,"programme":8,"title":775,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":776},"cordis-marie-skłodowska-curie-actions-award-221072","Mediterranean red coral management and conservation","One of the most characteristic Mediterranean species, Red Coral (Corallium rubrum, L. 1758), is intensively harvested by professional divers, supporting a specialized jewellery industry with a long tradition. However, all of its commercial stocks are overexploited now, and its populations consist of extremely young colonies (Santangelo & Abbiatti 2001; Tsounis et al. 2007). Recent data show that poaching of immature colonies has increased dramatically (Linares et al. 2003) and that the survival ",{"id":778,"funder":7,"programme":8,"title":779,"piName":10,"institution":780,"country":180,"year":13,"amount":10,"abstract":781},"cordis-marie-skłodowska-curie-actions-award-236156","Supramolecular Medicine: Modular, Double Dynamic and Orthogonal Functionalization of Supramolecular Biomaterials","TECHNISCHE UNIVERSITEIT EINDHOVEN","The main objective of this project is to create a new generation of smart biomaterials with great potential for tissue engineering and controlled drug delivery. Supramolecular polymers based on quadruple hydrogen bonding ureido-pyrimidinone (UPy) moieties (developed by the host group of Prof. Dr. E. W. Meijer in Eindhoven University of Technology, the Netherlands) will be employed as a basic scaffold. To fulfill the biomaterials trinity, namely tuneable mechanical properties, biodegradability an",{"id":783,"funder":7,"programme":8,"title":784,"piName":10,"institution":780,"country":180,"year":13,"amount":10,"abstract":785},"cordis-marie-skłodowska-curie-actions-award-235914","Self-assembly of Helical Functional Nanomaterials","The construction of nanostructured objects of well-defined size is of outmost importance for nanotechnology to surmount claims for potential applications and exploit improved chemical, physical or biological properties of a functional nanofeatured material. Biomedical imaging is one particular field of interest for water-compatible chemical self-assembly of nanosized objects. The outlined project aims to develop a methodology for the preparation of nanostructured objects in aqueous media with th",{"id":787,"funder":7,"programme":8,"title":788,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":789},"cordis-marie-skłodowska-curie-actions-award-237219","Towards an improved animal phylogeny: Congruence between morphology and molecules in basal metazoans","Comparative zoology is predicated on the assumption of a phylogenetic history. Today, phylogenetics relies on using explicit algorithmical methods to infer the past from features of contemporary species, with the fossil record as the only window to the history of life on our planet. A new field of research, called phylogenomics, uses large numbers of sequences to reconstruct the evolutionary history of organisms. Genomic data may palliate phylogenetic problems caused by sampling effects by expan",{"id":791,"funder":7,"programme":8,"title":792,"piName":10,"institution":780,"country":180,"year":13,"amount":10,"abstract":793},"cordis-marie-skłodowska-curie-actions-award-237543","Mimo mid-range radar for security applications in mainstream CMOS technology","The event of 11-Sepember incident has changed the face of the world as it was familiar to us. This event indicated the embarking of a new episode in the history of mankind which should have been associated with the security concerns. Although a large assortments of security devices has been put in action to prevent the happening of the world shaking events, however, the static nature of the available equipments has limited their applicability and it has stimulated the development of cheap, accur",{"id":795,"funder":7,"programme":8,"title":796,"piName":10,"institution":797,"country":168,"year":13,"amount":10,"abstract":798},"cordis-marie-skłodowska-curie-actions-award-236811","Electron transfer through multiple consecutive phenanthrenyl containing DNA","UNIVERSITAET BERN","Synthesis and development of novel DNA base pairs that are orthogonal in their recognition properties compared to the natural base pairs are avidly pursued by scientists.  Such novel base pairs are investigated as tools in biotechnology and in designing novel genetic systems. Interest in artificial base pairs continues because of their application in materials research and nanosciences.  Likewise charge transfer (CT) through the DNA duplex has received considerable attention and is being explore",{"id":800,"funder":7,"programme":8,"title":801,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":802},"cordis-marie-skłodowska-curie-actions-award-235938","Lignin and carbohydrate acylation in nonwoody plant cell-walls: Structural role, enzymatic cleavage and biotechnological relevance","The aim of this proposed Marie Curie project is to investigate lignin vs hemicellulose acylation\u002Fdeacylation in different non-woody angiosperms in connection with plant cell-wall structure and degradability. The focus will be on the use of esterases to remove acylating groups and to cleave the lignin-carbohydrate interface. Such an approach would help to develop a ‘white biotechnological’ process to enzymatically pretreat plant biomass for downstream applications, such as biofuel and the prepara",{"id":804,"funder":7,"programme":8,"title":805,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":806},"cordis-marie-skłodowska-curie-actions-award-235278","Knowledge Networks in Oncology: Weavers of Medical Innovation","This research seeks to advance conceptual and methodological propositions to analyse the sources and the effects of medical innovations. In particular, it will focus on the generation and use of scientific knowledge in the remit of health-care. It will take as empirical focus two areas of Oncology - Breast and Colorectal Cancers with a view to: 1. Understanding how the international knowledge bases of these two cancers emerged and developed. In particular, the project aims at situating and asses",{"id":808,"funder":7,"programme":8,"title":809,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":810},"cordis-marie-skłodowska-curie-actions-award-220933","Molecular mechanisms of germ cell migration across the mammalian blood-testis barrier","During spermatogenesis, germ cells located in the basal compartment of the seminiferous epithelium of the testis migrate across the blood-testis barrier (BTB) to continue differentiation on the luminal side. This trans-epithelial migration (TEM) requires regular restructuring of junctions present in the BTB. How germ cells pass the BTB, which harbours one of the tightest junctions present in the body, without compromising the integrity of the BTB is poorly understood. Several hypotheses have bee",{"id":812,"funder":7,"programme":8,"title":813,"piName":10,"institution":814,"country":304,"year":13,"amount":10,"abstract":815},"cordis-marie-skłodowska-curie-actions-award-234825","Effectiveness of Central Bank Communication","UNIVERSITE CATHOLIQUE DE LOUVAIN","This research project examines and compares the consequences of European Central Bank and Federal Reserve’s decisions and announcements on the whole distribution of financial market expectations about future monetary policy moves. The value added of this study is two-fold. First, we contribute to the rapidly expanding literature on central bank communication by shedding further light on asset price reactions to monetary policy: by looking at the whole distribution of market expectations, we can ",{"id":817,"funder":7,"programme":8,"title":818,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":819},"cordis-marie-skłodowska-curie-actions-award-235746","Unifying Ecological and Evolutionary Networks","The spatial distribution of genetic variation within species (i.e., genetic landscapes) is a consequence of the ecological and evolutionary processes that determine, ultimately, species distribution patterns. How these interacting processes shape the genetic and ecological diversity remains a key question of evolutionary ecology. In the last years, a huge amount of data at molecular and ecological level has emerged. But we still lack a theoretical framework to shed light on the role that ecologi",{"id":821,"funder":7,"programme":8,"title":822,"piName":10,"institution":797,"country":168,"year":13,"amount":10,"abstract":823},"cordis-marie-skłodowska-curie-actions-award-237001","High-resolution quantitative climate reconstructions for understanding current trends: the past 2000 years of Tasmanian climate variability","The last 2000 years form a critical period in global climate history. They span a significant length of time prior to major anthropogenic influences on climate and include the shift to industry-based societies. Lack of data from the Southern Hemisphere limits our understanding of climate change and ability to differentiate and delineate interactions between natural, forced and stochastic variability. High-resolution data spanning the last 2000 years from key locations in the Southern Hemisphere ",{"id":825,"funder":7,"programme":8,"title":826,"piName":10,"institution":827,"country":539,"year":13,"amount":10,"abstract":828},"cordis-marie-skłodowska-curie-actions-award-234879","Circadian regulation in the control of insulin and glucagon release and its role in Type 2 diabetes","UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE","Diabetes Mellitus is considered a bihormonal disorder that involves insulin resistance and insulin deficiency as well as relative or absolute high levels of glucagon. Recently, a strong association has been found between disturbances in circadian rhythms and metabolic disorders such as Diabetes Mellitus and Obesity. In this proposal we will use in vitro techniques to knockdown several clock genes in mouse pancreatic islets, MIN6 and alpha-TC1-9 cell lines to establish the role of clock genes in ",{"id":830,"funder":7,"programme":8,"title":831,"piName":10,"institution":814,"country":304,"year":13,"amount":10,"abstract":832},"cordis-marie-skłodowska-curie-actions-award-234867","Optimal pension design when individuals have different longevities","Following population ageing and some recently engaged reforms of pensions systems in several European countries, the question of how to link systems to longevity has become a topic of major interest. Not only longevity is a crucial aspect to take into account in pension reforms but also differential mortality has to be considered. Besides, pension systems have two main objectives; the first one being to provide resources to individuals in their old age, once they are not able to work anymore and",{"id":834,"funder":7,"programme":8,"title":835,"piName":10,"institution":538,"country":539,"year":13,"amount":10,"abstract":836},"cordis-marie-skłodowska-curie-actions-award-219265","Analysis of biodiversity changes on structural and functional properties of marine ecosystems under cumulative human stressors","The objective of my research is to quantify how the structure of marine food-webs has changed due to biodiversity changes and develop an understanding of how these changes have impacted ecosystem functioning. To accomplish this objective I will use an interdisciplinary approach applying meta-analysis of historical and recent data on species loss and ecosystem changes, food-web modelling and laboratory experiments. This first trial run approach will provide complementary information on how biodiv",{"id":838,"funder":7,"programme":8,"title":839,"piName":10,"institution":840,"country":180,"year":13,"amount":10,"abstract":841},"cordis-marie-skłodowska-curie-actions-award-235808","Diversity and beneficial properties of bacterial endophytes of arctic plants","RIJKSUNIVERSITEIT GRONINGEN","Arctic and semiarctic ecosystems cover 22% of the earth's terrestrial surface. These environments are very sensitive to disturbance, and are likely to be deeply affected by the climate change. At the same time, arctic microbiology has identified diverse communities of bacteria adapted to low temperatures, and arctic microbiota has been recognized as an untapped resource for sustainable industrial, agricultural and pharmaceutical applications. Unfortunately, the research on microbial diversity in",{"id":843,"funder":7,"programme":8,"title":844,"piName":10,"institution":845,"country":127,"year":13,"amount":10,"abstract":846},"cordis-marie-skłodowska-curie-actions-award-236845","Random Mappings and their Applications","HERIOT-WATT UNIVERSITY","I propose to investigate properties of random mappings with exchangeable in-degrees and of their variants. I focus especially on events and random characteristics relating to epidemic processes. It is expected that the corresponding probabilities and variables can be used to distinguish between possible models for disease spread, and could be used in the estimation of important model parameters which are of practical interest to epidemiologists. I also propose to study the joint distribution for",{"id":848,"funder":7,"programme":8,"title":849,"piName":10,"institution":850,"country":759,"year":13,"amount":10,"abstract":851},"cordis-marie-skłodowska-curie-actions-award-236264","Performing Spaces: Architecture, Spatiality, and Politics in European Ceremonial Cultures, circa 1550-1700","UNIVERSITY COLLEGE CORK -  NATIONAL UNIVERSITY OF IRELAND, CORK","This project explores the uses of architecture, architectural imagery and symbolic space in the festive cultures of early modern Europe. Historians and social scientists have often connected changing notions of elite public and private spaces to discourses of centralisation and modernisation in differing European ancien regimes. Combining textual and historical evidence, visual sources, evidence from material culture, and sociological and critical theory, this study will explore the competing de",{"id":853,"funder":7,"programme":8,"title":854,"piName":10,"institution":855,"country":127,"year":13,"amount":10,"abstract":856},"cordis-marie-skłodowska-curie-actions-award-235454","molecular and computational analysis of the leaf margin","THE UNIVERSITY OF SHEFFIELD","The question of how the shape and size multicellular organs is controlled is a basic question in biology. In plants, recent work from the Fleming lab has indicated that cells around the periphery of the organ (the margin cells) play a special role in influencing leaf size and shape. The peculiar shape of these cells raises the possibility that they play a mechanical role in constraining leaf size and shape. The aim of this project is to further investigate the function of cells at the leaf margi",{"id":858,"funder":7,"programme":8,"title":859,"piName":10,"institution":850,"country":759,"year":13,"amount":10,"abstract":860},"cordis-marie-skłodowska-curie-actions-award-220492","Track-etched Single Nanopores: Advanced Characterisation and New Applications","This fellowship aims to develop the career of the researcher to the point where he is in a very strong position to start his own research group and secure funding to do so. This will be achieved by complementing his existing scientific knowledge to give him a broad and well rounded-expertise on nanopore fabrication, characterisation and applications, giving him training in complementary skills such as proposal writing, teaching and management, allowing him to build collaborations and making him ",{"id":862,"funder":7,"programme":8,"title":863,"piName":10,"institution":855,"country":127,"year":13,"amount":10,"abstract":864},"cordis-marie-skłodowska-curie-actions-award-220866","Facing multiple predators - phenotypic integration in multiple antipredator traits","Phenotypic plasticity, the flexibility of organisms to adjust their phenotypes to changing environments, remains an exciting research area for scientist studying developmental biology, ecology and evolution. A recently emerging area of studying phenotypic plasticity is how prey integrate their response of suites of phenotypic traits across multiple environments. Because predation is a strong selective agent biasing the distribution, abundance and evolution of species, predator induced phenotypic",{"id":866,"funder":7,"programme":8,"title":867,"piName":10,"institution":840,"country":180,"year":13,"amount":10,"abstract":868},"cordis-marie-skłodowska-curie-actions-award-221393","Development of molecular probes for the non-invasive detection of liver fibrosis","Liver fibrosis is a progressive and fatal disease characterized by the accumulation of excessive amounts of scar tissue in response to chronic liver injury. The disease proceeds asymptomatically, until clinical signs of liver failure occur only in a very late stage of the disease. Early diagnosis would offer better treatment options. However, early detection and quantification of fibrosis, as well as determining the rate of fibrosis progression (fibrogenesis) or reversal (fibrolysis) still depen",{"id":870,"funder":7,"programme":8,"title":871,"piName":10,"institution":872,"country":168,"year":13,"amount":10,"abstract":873},"cordis-marie-skłodowska-curie-actions-award-236271","Origin, localization and biological function of malondialdehyde in plants","UNIVERSITE DE LAUSANNE","Malondialdehyde (MDA) has been considered in the past exclusively as the non-enzymatic oxidation by-product of many fatty acids with three (trienoic fatty acids) or more double bonds. However, nowadays MDA is known to be responsible of the up-regulation of many genes involved, principally, in abiotic stress responses in plants. The origin of a second MDA pool independent of trienoic fatty acids found in root tips of Arabidopsis thaliana is currently unidentified, which opens the question about t",{"id":875,"funder":7,"programme":8,"title":876,"piName":10,"institution":855,"country":127,"year":13,"amount":10,"abstract":877},"cordis-marie-skłodowska-curie-actions-award-219291","Multifunctional DNA light-switches: sensors and devices","Photoactive mono- and oligonuclear transition metal complexes containing DNA intercalative ligands will be synthesized. In the latter case, both homo- and heterometallic complexes will be synthesized. The photophysical properties of the complexes will be exploited to produce a number of outcomes: prototypical sensors for DNA sequences and\u002For structures that will produce a luminescent output on DNA binding, tools for investigating DNA\u002Fsubstrate binding events and the photophysical\u002Felectronic prop",{"id":879,"funder":7,"programme":8,"title":880,"piName":10,"institution":872,"country":168,"year":13,"amount":10,"abstract":881},"cordis-marie-skłodowska-curie-actions-award-236220","Plasma membrane to nucleus trafficking of the transcriptional co-activator BRX - characterization of a novel hormone signaling pathway in plants","A major question in biology is how external and internal cues are perceived by the organism and translated into an adequate response at the cellular level. For instance, organ growth in plants involves a phase of cell expansion, which requires extensive rearrangement of cell wall structure and is triggered by systemic cues, such as phytohormones. The complex topic how such cues are interpreted is of major interest in the field of cell biology, which has succeeded in deciphering various intra-cel",{"id":883,"funder":7,"programme":8,"title":884,"piName":10,"institution":872,"country":168,"year":13,"amount":10,"abstract":885},"cordis-marie-skłodowska-curie-actions-award-221254","Redox Potential as an Interface between Sleep homeostasis and Circadian Rhythms","Sleep is regulated by a homeostatic process that is activated by and counters the effect of sleep loss and a circadian process that determines the time-of-day sleep preferably occurs. The fine-tuned interaction between the two permits us to stay awake throughout the day and to remain asleep at night. Although these two processes are widely thought to operate independently, recent observations suggest that, at a molecular level, both processes use the same circadian transcription factors. Moreove",{"id":887,"funder":7,"programme":8,"title":888,"piName":10,"institution":728,"country":137,"year":13,"amount":10,"abstract":889},"cordis-marie-skłodowska-curie-actions-award-221462","Alterations in Memory Networks in Mild Cognitive Impairment and Alzheimer’s disease: Relating the Impact of Amyloid Burden with PIB-PET on Neuronal Activation as Assessed with fMRI","The main objective of this first 2-year period as a post-doctoral research fellow at BWH\u002FMGH Harvard Medical School is to get training in novel Magnetic Resonance Imaging (MRI) and Pittsburgh Compound B–Positron Emission Tomography (PIB-PET) techniques, their analysis methods, and applications to aging and age-related neurodegenerative diseases. The final purpose is to advance the candidate’s professional competence as an independent researcher and the integration of this knowledge and continuin",{"id":891,"funder":7,"programme":8,"title":892,"piName":10,"institution":696,"country":162,"year":13,"amount":10,"abstract":893},"cordis-marie-skłodowska-curie-actions-award-235499","Structural studies of P-type ATPases and their characterization in native membranes","P-type ATPases are cell-membrane pumps that are of fundamental importance in eukaryotes. The ion gradients created by Ca2+-ATPases or Na+,K+-ATPases are involved in signalling, maintaining the membrane potential as well as secondary active transport. Despite the recent progress in membrane protein crystallography, the lack of detailed structural information currently prevents a better understanding of function and specificity of cation pumps. One specific aim of this proposed research is to dete",{"id":895,"funder":7,"programme":8,"title":896,"piName":10,"institution":855,"country":127,"year":13,"amount":10,"abstract":897},"cordis-marie-skłodowska-curie-actions-award-236282","Optimal seismic rehabilitation of reinforced concrete buildings using FRP composites","This study aims to develop an original practical optimisation technique for seismic rehabilitation of RC structures using FRP composites. The proposed method is capable of producing retrofit designs that minimize the total material cost of FRP by at least 20% while optimising the seismic performance of the structure. Based on the outcomes of this study, design guidelines for optimum seismic rehabilitation of reinforced concrete buildings using FRP composites will be provided. These design guidel",{"id":899,"funder":7,"programme":8,"title":900,"piName":10,"institution":814,"country":304,"year":13,"amount":10,"abstract":901},"cordis-marie-skłodowska-curie-actions-award-235618","Molecular Characterisation of the INTRAcellular Plant Aquaporin Trafficking and Hetero-oligomerisation","In plants, the movement of water and small neutral solutes across the plasma membrane (PM) is dependent on the number and activity of water channels, named aquaporins (AQP). Little is known about mechanisms by which AQPs reach their final destination. Recent studies have shown that PIP (Plasma membrane Intrinsic Protein) aquaporins belonging to two subgroups, PIP1 and PIP2, physically interact to regulate their trafficking and the cell membrane water permeability. Therefore, this mechanism might",{"id":903,"funder":7,"programme":8,"title":904,"piName":10,"institution":723,"country":304,"year":13,"amount":10,"abstract":905},"cordis-marie-skłodowska-curie-actions-award-236555","Role of netrin signaling in blood vessel pathfinding","Netrins were described as bifunctional guidance cues, capable of attracting or repelling developing axons via activation of receptors of the deleted in colorectal cancer (DCC) and uncoordinated 5 (UNC5) families, respectively. Recently, they have also been implicated in the process of blood-vessel formation or angiogenesis, where they may also act as bifunctional cues, but their effect is unclear, with previous reports showing contradictory endothelial behaviors. In order to clarify the pro- or ",{"id":907,"funder":7,"programme":8,"title":908,"piName":10,"institution":909,"country":234,"year":13,"amount":10,"abstract":910},"cordis-marie-skłodowska-curie-actions-award-237435","Experimental reconstruction of volcanic explosions: understanding the fragmentation energy balance and seismic signals","LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN","Volcanic explosions can have devastating effects on their surrounding area and communtiies, so it is important to improve our understanding of the controls on how energetic volcanic explosions are and the interpretation of the seismic signals that they generate. Volcanic explosions are driven by ascent and depressurisation of magma, which result in the exsolution of large volumes of gas. If the gas cannot escape through permeable pathways, pressure in the magma will build up, resulting in fragme",{"id":912,"funder":7,"programme":8,"title":913,"piName":10,"institution":914,"country":180,"year":13,"amount":10,"abstract":915},"cordis-marie-skłodowska-curie-actions-award-219996","Femtosecond mid-infrared study of water at electrified interfaces","STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN","Water has a paramount importance in chemical, biochemical and electrochemical processes. However, very little information is known about the microscopic mechanism by which water affects these processes. This is due to the fact that water in the condensed phase shows ultrafast (sub-picosecond) molecular dynamics and forms an extremely inhomogeneous system. Femtosecond pump-probe mid-infrared spectroscopy is ideally suited to distinguish different types of water molecules and it also provides suff",{"id":917,"funder":7,"programme":8,"title":918,"piName":10,"institution":909,"country":234,"year":13,"amount":10,"abstract":919},"cordis-marie-skłodowska-curie-actions-award-237369","Towards A Behavioral Theory of Organizational Ownership: A Comparative Study in Shareholder Behavior","This Project aims to overcome inferential leaps from size of shareholdings to shareholder behavior by investigating shareholder attitudes towards ownership of the organization directly by means of a survey instrument specifically designed for this purpose. 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