[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2010":3,"awarded-stats-msca-postdoctoral-fellowship":936},{"awarded":4,"total":935},[5,16,23,29,36,42,48,54,59,65,70,75,81,86,93,100,104,109,114,119,124,129,135,142,148,154,159,164,170,174,179,184,189,193,199,204,209,214,219,223,227,232,237,241,245,249,253,257,261,266,270,274,278,282,287,291,295,300,304,308,312,317,321,326,331,335,339,343,349,354,358,362,368,372,376,380,387,392,396,401,405,409,413,417,421,425,429,433,437,443,447,452,457,462,466,470,474,478,482,486,490,494,498,503,508,512,516,520,527,531,536,540,544,548,552,556,560,564,568,573,579,583,588,592,596,600,604,608,612,616,620,624,629,633,637,641,646,650,654,658,662,666,672,676,682,686,690,695,699,703,707,711,715,719,724,728,733,737,741,745,749,753,758,763,767,772,776,782,786,791,796,800,806,810,815,821,826,830,834,838,842,847,851,856,860,865,871,875,879,884,890,894,899,904,908,913,917,921,925,930],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"cordis-marie-skłodowska-curie-actions-award-980056","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","Identification of genes linked to gum quality in the gum producing gum arabic tree - Acacia senegal (L.) Willd using the association genetics approach",null,"KENYA FORESTRY RESEARCH INSTITUTE","KE",2010,"€85,813","There is currently a growing demand for reliable high quality gum producing Acacia senegal. This is because the existing natural woodland based systems show considerable variability in gum quality. As well as the established molecular markers (AFLPs and SS Rs), the ASGEN study will employ the novel and innovative approach of association genetics in order to identify markers that are linked to gum quality or genes responsible for gum quality.Gum quality is a good example of a complex trait where ",{"id":17,"funder":7,"programme":8,"title":18,"piName":10,"institution":19,"country":20,"year":13,"amount":21,"abstract":22},"cordis-marie-skłodowska-curie-actions-award-980068","Generation of Inter-neuron deficient mouse model","INSTITUTE FOR GENETIC ENGENIERING AND MOLECULAR BIOLOGY","AR","€83,275","The neural circuits underlying the formation of functional networks in the cerebral cortex constitute one of the most complex physical systems in the World. Much of this complexity arises during development through the interaction of two distinct neuronal types, glutamatergic projection neurons and aminobutyric containing (GABAergic) interneurons.Recently, interneuron dysfunction has been associated with severe neurological and psychiatric disorders (e.g. epilepsy, schizophrenia and bipolar diso",{"id":24,"funder":7,"programme":8,"title":25,"piName":10,"institution":26,"country":20,"year":13,"amount":27,"abstract":28},"cordis-marie-skłodowska-curie-actions-award-980067","Electronic structure of nanosystems: Density functional theory approach","CENTRO ATOMICO BARILOCHE","€50,422","One of the core concepts in nanoscience and nanotechnology is the bottom-up approach, taking electrons, atoms, or molecules as the building blocks from which to create man-made nanosystems with the specific and desired electronic, biological, material, mechanical, or environmental properties. This approach however, poses a new and fundamental scientific challenge: the mastering of the way in which electrons, atoms, or molecules interact which each other, governed by the non-intuitive laws of qua",{"id":30,"funder":7,"programme":8,"title":31,"piName":10,"institution":32,"country":33,"year":13,"amount":34,"abstract":35},"cordis-marie-skłodowska-curie-actions-award-980069","Modelling anisotropy and destructuration in unsaturated soils","FUNDAÇÃO DE EMPREENDIMENTOS CIENTIFICOS E TECNOLÓGICOS","BR","€65,199","Unsaturated conditions, where pore in soil are partly filled with water and partly filled with air) occur widely both as natural soils and as fill materials. The hydro-mechanical behavior of unsaturated soils is considerably more complex than that of saturated soils. Overall, with unsaturated soils, there are problems associated with the testing methodologies, sampling and test duration.Consequently, the understanding of unsaturated soil behavior lags behind the state-of-the-art of saturated soi",{"id":37,"funder":7,"programme":8,"title":38,"piName":10,"institution":39,"country":40,"year":13,"amount":10,"abstract":41},"cordis-marie-skłodowska-curie-actions-award-252792","Strategic Management tools for Art Museums","THE BOSTON CONSULTING GROUP S.R.L","IT","The museum industry is characterized by a series of features that make it a challenging environment in which to operate and compete. One of these features is that, as most cultural industries, product performance must be viewed as multidimensional, because cultural goods have a twofold nature: they are at the same time artistic products and economic products. Moreover, quality evaluation in the museum industry is inherently difficult since products of the creative industries differ unpredictably",{"id":43,"funder":7,"programme":8,"title":44,"piName":10,"institution":45,"country":46,"year":13,"amount":10,"abstract":47},"cordis-marie-skłodowska-curie-actions-award-251357","Cognitive distortions in eating disorders: Development and application of a model for thought-shape fusion","UNIVERSITE SAVOIE MONT BLANC","FR","Cognitive distortions are characterized by faulty, irrational thought processes, and are characteristic of psychopathology. Within the past decade, new research has emerged that suggests that there is a specific cognitive distortion associated with eating disorders. This distortion has been identified as ‘thought-shape fusion’ (TSF), and is associated with the belief that just thinking about eating fattening foods can lead to weight gain, feelings of fatness, and perceived moral wrong-doing. The",{"id":49,"funder":7,"programme":8,"title":50,"piName":10,"institution":51,"country":52,"year":13,"amount":10,"abstract":53},"cordis-marie-skłodowska-curie-actions-award-254919","Cell-type specific features of serotonergic neurons in the raphe nuclei","FUNDACAO CALOUSTE GULBENKIAN","PT","Serotonin (5-Hydroxytryptamine, 5-HT) has long been known to be involved in a variety of behavioral, cognitive and emotional processes and is commonly pharmacologically targeted in the treatment of some major psychiatric and neurological diseases. Most of the brain 5-HT innervation arises from a specific neuronal network in the brainstem, the raphe nuclei RN. For a better understanding of the brain 5-HT functions an in depth knowledge of RN network is required with a special emphasis on the acti",{"id":55,"funder":7,"programme":8,"title":56,"piName":10,"institution":57,"country":46,"year":13,"amount":10,"abstract":58},"cordis-marie-skłodowska-curie-actions-award-236308","Stochastic Laplacian Growth","UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6","Recent breakthrough in the theory of 2D growth, due to application of analytic theory of stochastic conformal mappings, opened new prospectives for solution of fundamental long-standing problems in the studies of interface dynamics and pattern formation. The research field has been enriched by new effective approaches, emerged from theory of integrable systems and analytic function theory, to deal with dynamics of a moving front between two distinct phases driven by a harmonic scalar field as we",{"id":60,"funder":7,"programme":8,"title":61,"piName":10,"institution":62,"country":63,"year":13,"amount":10,"abstract":64},"cordis-marie-skłodowska-curie-actions-award-237667","Pancreatic stellate cells - sentinels for tissue damage?","CANCER RESEARCH UK LBG","UK","Pancreatic ductal adenocarcinoma (PDA) is a lethal disease killing about 7000 people in the United Kingdom every year. PDA is resistant to conventional therapy. A hallmark of PDA is the abundance of desmoplastic stroma, which is thought to originate by activation of pancreatic stellate cells (PSC). Unfortunately, little is know about the precise role of PSC in the physiology of the pancreas. In this proposal I will investigate the function of the pancreatic stellate cell in health and during tum",{"id":66,"funder":7,"programme":8,"title":67,"piName":10,"institution":68,"country":63,"year":13,"amount":10,"abstract":69},"cordis-marie-skłodowska-curie-actions-award-252258","Pheromone Identification for Environmentally Responsible Control of Thrips","UNIVERSITY OF KEELE ROYAL CHARTER","Thrips are insects that are important crop pests in agriculture and horticulture. They cause most damage to protected (greenhouse) crops, which have an annual EU production of 37 billion euros. Growers are struggling to control thrips but are also under pressure to reduce pesticide use. The EU Directive on the Sustainable Use of Pesticides (2009) requires alternatives to pesticides to be used wherever possible. There is also the imminent threat that an invasive species, Thrips palmi, will devast",{"id":71,"funder":7,"programme":8,"title":72,"piName":10,"institution":73,"country":10,"year":13,"amount":10,"abstract":74},"cordis-marie-skłodowska-curie-actions-award-254623","Identification and exploitation of user communities for efficiently handling large-scale folksonomies","UNIVERSITY COLLEGE LONDON","For centuries, classification has been exploited by users to contextualize any aspect of human knowledge. An emerging way to classify objects is given by folksonomies. The term folksonomy is currently used to indicate a data structure that allows users to classify various kinds of resources by means of plain keywords freely chosen by them.Folksonomies are gaining wide popularity but, although they overcome important weak points affecting taxonomy systems, they generally imply a lack of precision",{"id":76,"funder":7,"programme":8,"title":77,"piName":10,"institution":78,"country":79,"year":13,"amount":10,"abstract":80},"cordis-marie-skłodowska-curie-actions-award-255211","Organization, plasticity and perceptual functions of neuronal circuits in a higher olfactory forebrain area","Novartis Forschungsstiftung","CH","The brain processes sensory information in a succession of interconnected brain areas. Response complexity tends to increase with distance from the sensory organ, and neurons in higher brain areas exhibit complex response properties that may also reflect memory processes and behavioural associations. Little is known about how such complex representations emerge. I propose to confront this problem by studying forebrain olfactory processing in zebrafish, utilising the extensive studies available o",{"id":82,"funder":7,"programme":8,"title":83,"piName":10,"institution":84,"country":46,"year":13,"amount":10,"abstract":85},"cordis-marie-skłodowska-curie-actions-award-254156","Aromatic Foldamers for Single Molecule Electronics","UNIVERSITE BORDEAUX I","Recent work has demonstrated 1°) the synthetic accessibility of rigid, rod-like, helically folded aromatic amide oligomers of very large size – up to 48 units, over 12 kDa, and 7 nm long; and 2) the ability of short segments of the same oligomers to transport electrons at very fast rates via a super exchange mechanism. This project plans to investigate the potential of such unusual synthetic objects as building blocks in molecular electronics. The research plan involves several parallel tracks c",{"id":87,"funder":7,"programme":8,"title":88,"piName":10,"institution":89,"country":90,"year":13,"amount":91,"abstract":92},"cordis-marie-skłodowska-curie-actions-award-254649","Transboundary territorial cooperation, policy learning and the Europeanisation of urban and spatial planning policies in the Mediterranean area","INSTITUT UNIVERSITARI D'ESTUDIS EUROPEUS","ES","€146,717","The aim of the research is to investigate whether, and how, policy learning in cities and regions occurs as a result of participation in European transboundary cooperation projects; and whether this leads to a form of ‘Europeanisation’ of territorial, spatial and urban planning policies in the Southern European context. ‘Transboundary cooperation’ refers to various forms of cooperation across national borders between cities, regions and other organisations which cooperate at various geographical",{"id":94,"funder":7,"programme":8,"title":95,"piName":10,"institution":96,"country":97,"year":13,"amount":98,"abstract":99},"cordis-marie-skłodowska-curie-actions-award-254528","Synaptic vesicle acidification and refilling dynamics","Westfälische Wilhelms-Universität Münster","DE","€161,661","In newly endocytosed synaptic vesicles, a proton electrochemical gradient is produced by the vacuolar-type H+-ATPase in order to power transport processes across the membrane. The mechanisms responsible for vesicle refilling have been largely investigated on isolated synaptic vesicles. Biochemical investigation indicates that the preference of vesicle filling for each component of the electrochemical gradient, namely the membrane potential and the proton gradient, depends on the specific transpo",{"id":101,"funder":7,"programme":8,"title":102,"piName":10,"institution":73,"country":10,"year":13,"amount":10,"abstract":103},"cordis-marie-skłodowska-curie-actions-award-237794","Self-Knowledge in Consumer Decision Making","The purpose of the proposed project is to use a phenomenon called choice blindness to study self-knowledge and preference formation in the domain of consumer choice and economic decision making. Choice blindness refers to the experimental finding that people sometimes fail to notice mismatches between their intended choice and the outcome they are presented with, while nevertheless offering introspectively derived reasons for why they chose this alternative rather than the other. The effect has ",{"id":105,"funder":7,"programme":8,"title":106,"piName":10,"institution":107,"country":46,"year":13,"amount":10,"abstract":108},"cordis-marie-skłodowska-curie-actions-award-253783","MODELLING OF ELECTROMAGNETIC TRANSIENTS AND PLC ENERGY SERVICES","UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II","Power Line Communication (PLC) technology enables broadband data transfer through power lines. Although promising it is still not fully developed and standardized. One major concern is the EMC radiation problem that is still controversial. However, it seems that experimental or commercial deployments are working practically without complaints. PLC channel is a power transmission line (TL) itself. It may be subject to unwanted disturbances and failures caused by electromagnetic (EM) transients of",{"id":110,"funder":7,"programme":8,"title":111,"piName":10,"institution":112,"country":46,"year":13,"amount":10,"abstract":113},"cordis-marie-skłodowska-curie-actions-award-252318","Stochastic recursions and limit theorems","UNIVERSITE DE RENNES I","The project concerns investigations of stochastic recursions, related limit theorems and their applications in branching processes. Recently we have proved many properties of matrix recursions, when the Lyapunov exponent is negative, including precise description of the tail of the stationary measure and resulting limit theorems. We are going to develop further the methods we have used and apply them to study new problems. The main research objectives are:- Studying of stochastic recursions when",{"id":115,"funder":7,"programme":8,"title":116,"piName":10,"institution":117,"country":63,"year":13,"amount":10,"abstract":118},"cordis-marie-skłodowska-curie-actions-award-253516","The contribution of multi-stakeholder partnerships to sustainable landscape management","THE MACAULAY LAND USE RESEARCH INSTITUTE","There is ongoing political and scientific debate about how to achieve sustainable management of natural resources that will benefit rural communities’ economic development while protecting and enhancing natural assets. Non-governmental multi-stakeholder groups are an important link between policies and on-ground management. There is limited knowledge on the groups’ contribution to sustainable development and only scattered information on how efficiently the activities of these groups can be infl",{"id":120,"funder":7,"programme":8,"title":121,"piName":10,"institution":122,"country":46,"year":13,"amount":10,"abstract":123},"cordis-marie-skłodowska-curie-actions-award-253368","COMPUTATIONAL COMPLEXITY MEETS AUTOMATA THEORY","Université Paris Diderot-Paris 7","Computational Complexity classifies computational problems according to difficulty. Although a rich map of time complexity classes has already been developed (P, EXP, EEXP, ...",{"id":125,"funder":7,"programme":8,"title":126,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":128},"cordis-marie-skłodowska-curie-actions-award-252067","MIcrowave emission LinEwidth of Spin-Torque-Oscillators and associated phase NoisE","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","The aim of this project is to advance the performances of a spinelectronics based microwave oscillator. These spintronics oscillators (STO) make use of the recently discovered spin transfer torque effect by which the magnetization of a thin magnetic layer can be set into perpetual steady state oscillations. These magnetization oscillations are translated into an ac output voltage by virtue of the giant or tunnelling magneto-resistance while its Gigahertz frequency can be tuned by the spin polari",{"id":130,"funder":7,"programme":8,"title":131,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":134},"cordis-marie-skłodowska-curie-actions-award-254125","Disentanglement of the 1D electronic properties of Single-Walled Carbon Nanotubes via separation, co-doping and filling","UNIVERSITAT WIEN","AT","This project comprises a combined theoretical and experimental approach to engineer substitutionally doped and metallicity separated single walled carbon nanotubes with novel fillings with tailored electronic and optical properties. It aims at significantly advancing the limits of current capabilities that employ functionalized nanotubes with an option to underpin the research field in a short timescale. These predicted and engineered 1D structures act simultaneously as primed bulk n- or p- type",{"id":136,"funder":7,"programme":8,"title":137,"piName":10,"institution":138,"country":139,"year":13,"amount":140,"abstract":141},"cordis-marie-skłodowska-curie-actions-award-252836","protein archeology : reconstructed ancestors for protein engineering and crystallography","WEIZMANN INSTITUTE OF SCIENCE","IL","€174,653","Advances in molecular evolution led to the novel concept of ancestral resurrections, or reconstructions. These allow the exploration of the mechanisms by which new protein families diverged. Reconstructed ancestors are also inherently more prone to functional divergence, and exhibit higher thermal stability, making them more tolerant to mutations, and potentially more evolvable. However, to date, very few ancestors have been resurrected, and the experimental methodologies are still lacking. I ai",{"id":143,"funder":7,"programme":8,"title":144,"piName":10,"institution":145,"country":146,"year":13,"amount":10,"abstract":147},"cordis-marie-skłodowska-curie-actions-award-235429","Multilevel Modelling for Predictive Toxicology","JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION","BE","Computational toxicology seeks to apply modern computing and information technology, with molecular biology and chemistry to predict toxicity of chemical compounds and to improve risk assessment. Recent technological breakthroughs have made it possible to discover new mechanisms of toxic action and have opened the way for the implementation of systems biology and in silico methods in the field of toxicology. Coupling different levels of modelling will enable the integration of disparate data and",{"id":149,"funder":7,"programme":8,"title":150,"piName":10,"institution":151,"country":146,"year":13,"amount":152,"abstract":153},"cordis-marie-skłodowska-curie-actions-award-252139","Factors regulating the input of terrestrial material and patterns in food web structure in African inland aquatic systems","KATHOLIEKE UNIVERSITEIT LEUVEN","€168,800","In many parts of Africa, human populations depend directly or indirectly on rivers and wetlands. Despite this importance, basic ecological aspects of most aquatic communities are still poorly understood and destructive activities such as deforestation and dam construction are in rapid ascent, threatening waterways and their wetlands. It is therefore crucial to improve our understanding on the ecology of these areas, so that the responses of aquatic communities to the different alterations to the",{"id":155,"funder":7,"programme":8,"title":156,"piName":10,"institution":157,"country":97,"year":13,"amount":10,"abstract":158},"cordis-marie-skłodowska-curie-actions-award-254598","Multilingual democracy experiments in movements: from transnational activists to local decision-makers","FREIE UNIVERSITAET BERLIN","The project brings together a micro-sociology of democracy with a politics of multilingual deliberation in arenas of protest and decision-making. Designed as a pilot study, the project will explore the relevance that activists’ practices of face-to-face translation, developed for transnational discursive democracy experiments in social movements, can have for activists and officials also at domestic level in multilingual group settings. Having conducted two comparative studies on supranational d",{"id":160,"funder":7,"programme":8,"title":161,"piName":10,"institution":162,"country":79,"year":13,"amount":10,"abstract":163},"cordis-marie-skłodowska-curie-actions-award-237397","Nonlinear spectral problems and wave propagation in crystals","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","Nonlinear spectral problems frequently occur when damping effects or frequency dependencies are included in a model. Many physically relevant spectral problems induce symmetries in the spectrum. Numerical methods that ignore structure often break these qualitatively important symmetries, which may lead to physically meaningless or unstable results. The importance of preserving eigenvalue symmetries of a matrix polynomial has been discussed in recent years. However, the whole chain, from spectral",{"id":165,"funder":7,"programme":8,"title":166,"piName":10,"institution":167,"country":168,"year":13,"amount":10,"abstract":169},"cordis-marie-skłodowska-curie-actions-award-252934","Rational design of a lipopolysaccharide adjuvant for tuberculosis vaccines","RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU","NL","Tuberculosis, a disease caused by the bacterium Mycobacterium tuberculosis, kills 2-3 million people per year. Although an attenuated strain of M.bovis called BCG is widely used as vaccine against TB, its effectiveness is generally considered as insufficient. Our new approach for BCG improvement is to add a novel type of adjuvant, based on genetically engineered versions of the lipopolysaccharide (LPS) from Neisseria meningitidis (Nm). The modifications aim at (i) specific targeting to dendritic",{"id":171,"funder":7,"programme":8,"title":172,"piName":10,"institution":162,"country":79,"year":13,"amount":10,"abstract":173},"cordis-marie-skłodowska-curie-actions-award-237346","Analysis of the kinetochore architecture and dynamics using a mass spectrometry based integrative structural approach","A mechanistic understanding of a living cell requires the characterization of the architecture and dynamic assembly of its macromolecular complexes. The proposed project describes a novel integrative approach to determine the topology of protein networks and higher order assemblies using chemical crosslinking, state of the art mass spectrometry (MS) and cryo-electron tomography (cryo-ET). This MS based strategy will enable the high-throughput detection and integration of structural data of biolo",{"id":175,"funder":7,"programme":8,"title":176,"piName":10,"institution":177,"country":168,"year":13,"amount":10,"abstract":178},"cordis-marie-skłodowska-curie-actions-award-252379","The Cosmic Soul: Renaissance Humanism and Natural Philosophy","STICHTING RADBOUD UNIVERSITEIT","I am proposing to spend two years at the Center for the History of Philosophy and Science (CHPS) at the Faculty of Philosophy of Radboud University Nijmegen (the Netherlands). There, I propose to carry out a large research project and at the same time to acquire a number of new skills in the domains of teaching, editorship, organization and research methodology. I have good reasons for believing that my planned publications, together with my expanded curriculum, will allow me to compete successf",{"id":180,"funder":7,"programme":8,"title":181,"piName":10,"institution":151,"country":146,"year":13,"amount":182,"abstract":183},"cordis-marie-skłodowska-curie-actions-award-254009","Functional Supramolecular Networks on Surfaces","€159,100","FUNSURF is an interdisciplinary research project which lies at a natural meeting point between chemistry, physics, materials science and nanotechnology. The project will enable a bright young scientist with an impressive track record to gain a high level of cross-disciplinary training in diverse new aspects of supramolecular self-assembly and reactivity, scanning probe microscopy, photochemistry and optical spectroscopy. The training-through-research basis of FUNSURF focuses on the design, synth",{"id":185,"funder":7,"programme":8,"title":186,"piName":10,"institution":151,"country":146,"year":13,"amount":187,"abstract":188},"cordis-marie-skłodowska-curie-actions-award-252951","Coulomb excitation of ground- and isomeric state of neutron-deficient polonium isotopes: a study of shape coexistence in the Z=82 region","€160,600","The object of the present proposal is the study of the intriguing phenomenon of shape coexistence, whereby an atomic nucleus exhibits different shapes (e.g. spherical, oblate, prolate) at low excitation energy. The measurements will give quantitative information about the nature of the shape coexistence and the interplay between single-nucleon and collective degrees of freedom and should, therefore, reveal important new insight in the underlying mechanisms that determine the nuclear structure. T",{"id":190,"funder":7,"programme":8,"title":191,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":192},"cordis-marie-skłodowska-curie-actions-award-254368","Role of astrocytes in Huntington's Disease: characterization of a novel mouse model with targeted expression of mutant huntingtin in the striatum","Huntington’s disease (HD) is an inherited neurodegenerative disease, which has no cure, resulting from the mutation of the gene coding for huntingtin protein (htt). Clinically, HD patients present with progressive involuntary spasmodic movements and cognitive impairments. Post-mortem studies of HD patients reveal severe atrophy of the striatum, reflecting a selective neuronal loss of medium spiny neurons (MSNs). The path leading to MSNs death remains unknown. Conversely, astrocytic dysfunction m",{"id":194,"funder":7,"programme":8,"title":195,"piName":10,"institution":196,"country":97,"year":13,"amount":197,"abstract":198},"cordis-marie-skłodowska-curie-actions-award-252984","Magnetic Coordination Cluster Polymers","RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN","€222,982","Coordination polymers exhibiting magnetic properties can be considered as strategic and revolutionary materials due to their great potential in the development of ‘intelligent’ multifunctional materials including magnetic sensors and molecular spintronics precursors. The main goal of the proposed project “Magnetic Coordination Cluster Polymers” is the development on novel generation of functional materials via controlled assembly of coordination polymers based on polynuclear coordination cluster",{"id":200,"funder":7,"programme":8,"title":201,"piName":10,"institution":202,"country":168,"year":13,"amount":10,"abstract":203},"cordis-marie-skłodowska-curie-actions-award-255375","PLETHORA transcriptions factors, new players in the control of phyllotaxis in Arabidopsis thaliana","UNIVERSITEIT UTRECHT","The mathematical regularity of plant organ initiation, also known as phyllotaxis, has always intrigued mathematicians and botanists. Only recently was established that the plant hormone auxin has a major role in regulating organ positioning at the shoot apex of plants. Specific spatial accumulation of auxin induces organ formation and control organ spacing. The current model for phyllotaxis relies on polar auxin transport via auxin efflux facilitators of the PIN family, and postulated positive f",{"id":205,"funder":7,"programme":8,"title":206,"piName":10,"institution":207,"country":168,"year":13,"amount":10,"abstract":208},"cordis-marie-skłodowska-curie-actions-award-253603","Preparation of Multi-Functional Metal Organic Frameworks catalysts","TECHNISCHE UNIVERSITEIT DELFT","The overall aim of this project is to engineer new mono and multifunctional nanostructured solids to be used as catalyst for multi-step, one-pot reactions. The key objectives are: 1. Create stable nano-structured super basic catalysts based on Metal Organic Frameworks (MOFs) by using synthetic and\u002For post-synthetic approaches. 2. Create nano-structured solids containing covalently bonded sulphonic groups by using synthetic and\u002For post synthetic methods. 3. Create acid MOFs with metal nanoparticl",{"id":210,"funder":7,"programme":8,"title":211,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":213},"cordis-marie-skłodowska-curie-actions-award-252917","Ancient South Arabian confession of sins texts","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","Public confession of sins is one of the less known religious practice in pre-Islamic South Arabia. It is revealed by several inscriptions on limestone tablets that were probably shown publicly inside or nearby the temple of the divinity to which the confession was directed. The vast majority of these documents comes from the northern part of South Arabia (the Jawf area). The repentant can be an individual (frequently a woman), a small group or the entire community. About 15 new confession texts ",{"id":215,"funder":7,"programme":8,"title":216,"piName":10,"institution":151,"country":146,"year":13,"amount":217,"abstract":218},"cordis-marie-skłodowska-curie-actions-award-252407","Induced electrodeposition of nanostructures as nanowires and nanotubes consisting of cobalt-based multilayers for MEMS applications","€158,600","Purpose of the project: This project is focused on the synthesis by induced electrodeposition of nanowires and nanotubes as multilayered structures consisting of cobalt alloys with refractory metals like Mo and W. Hereto the superfilling of nanopores present as arrays in anodized aluminium oxide (AAO), will be investigated in-depth. First proofs of principles have been recently achieved by the applicant. The background of the host institution on electrodeposition in micro-pores (e.g. vias used i",{"id":220,"funder":7,"programme":8,"title":221,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":222},"cordis-marie-skłodowska-curie-actions-award-252095","Spatially-Implicit Modelling of Plankton Ecosystems","The aim of SIMPLE is to investigate and parameterise the influence of small-scale spatial variability in plankton concentrations on the behaviour of large-scale mean fields. This is necessary for accurate plankton ecosystem models as biogeochemical subunits of predictive climate models, which must account for the influence of plankton ecosystems on the biosphere, and as tools to predict the large-scale effects of climate change on sensitive marine ecosystems, which support economically-critical ",{"id":224,"funder":7,"programme":8,"title":225,"piName":10,"institution":162,"country":79,"year":13,"amount":10,"abstract":226},"cordis-marie-skłodowska-curie-actions-award-252926","Self-assembly of magnetic core-shell nanoparticles at liquid-liquid interfaces for the fabrication of ultra-thin responsive membranes","The goal of this project is to study and control the self-assembly of superparamagnetic iron oxide nanoparticles (NPs) stabilized by a shell of responsive polymers at liquid-liquid interfaces in order to crosslink them into ultra-thin, mechanically stable, responsive membranes. This novel “smart” material will have unique properties suitable for applications in miniaturized lab-on-chip and other microfluidics devices. The interdisciplinary nature of the project contributes to its scientific nove",{"id":228,"funder":7,"programme":8,"title":229,"piName":10,"institution":162,"country":79,"year":13,"amount":230,"abstract":231},"cordis-marie-skłodowska-curie-actions-award-254688","R&D Network Life Cycles","€232,504","It is widely agreed that research and development (R&D), with its subsequent technological innovations, is the driving force in economic growth. R&D activities are distributed across different economic actors, notably firms, which interact in many ways, e.g. through collaboration or knowledge transfer. Using a conceptual network approach, these firms can be seen as nodes and their interactions as links of a network that may evolve over time, both with respect to the actors and their interactions",{"id":233,"funder":7,"programme":8,"title":234,"piName":10,"institution":235,"country":46,"year":13,"amount":10,"abstract":236},"cordis-marie-skłodowska-curie-actions-award-236316","Fish community structure and ecosystem properties in a global change context","UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES","Humans are modifying the composition of biological communities through habitat loss and resource depletion (fishing). Changes in biota may have even greater effects on ecosystem properties than changes in abiotic parameters. However, the vast majority of studies dealing with the relationship between the composition of ecological communities and ecosystem functioning have concentrated on relatively simple systems (primary producers), have investigated at small scales (experiments) and have only c",{"id":238,"funder":7,"programme":8,"title":239,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":240},"cordis-marie-skłodowska-curie-actions-award-255109","Epigenetic regulation of the adaptative response of C.reinhardtii to development and environmental stresses:Characterization of .Histone PTMS,gene regulation and pathways employing a Systems Biology","Reversible modifications of DNA sequence and histones serve as a fast and accurate process to regulate gene expression. These mechanisms act specifically and co-ordinately, constituting what is called the epigenetic code, and influence a multitude of cellular processes including, besides the regulation of the transcription, differentiation, DNA replication, repair or imprinting, among others. Aided by the use of multidisciplinary combination of new technologies such as epigenomics, transcriptomi",{"id":242,"funder":7,"programme":8,"title":243,"piName":10,"institution":207,"country":168,"year":13,"amount":10,"abstract":244},"cordis-marie-skłodowska-curie-actions-award-253096","Bacterial alginate: isolation, fine structure characterization and role in aerobic granular sludge formation","Aerobic sludge granulation is a promising innovative technology with the potential to be an alternative to the activated sludge process. It allows running a wastewater treatment plant with 30% less energy input, and requiring 75% less space combining with significant lower investment costs. Aerobic granules’ stability is the main concern of this process. It is strongly connected with the property of exopolysaccharides, particularly the bacterial alginates, which have been recently shown to be mo",{"id":246,"funder":7,"programme":8,"title":247,"piName":10,"institution":145,"country":146,"year":13,"amount":10,"abstract":248},"cordis-marie-skłodowska-curie-actions-award-255149","MIMYCS, A framework for simulating maize kernels mycotoxin contamination in Europe","Maize is one of the main crops grown for human food and livestock feed, using more than 8.5 million ha of cropland annually in Europe. The crop is heavily affected by mycotoxin problems throughout the world. Mycotoxins are toxic compounds recognised as the principal cause of human and animal chronic intoxications. In addiction to health risk, regulations of the European Union and other countries of the world on the maximum levels of mycotoxins in cereals have had an important socio-economic impa",{"id":250,"funder":7,"programme":8,"title":251,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":252},"cordis-marie-skłodowska-curie-actions-award-236509","Mediation of Employment Rights Disputes","Mediation gives the parties in dispute the opportunity to reach a settlement without a court hearing and with the help of an independent third party, a mediator. This can provide cost-effective and quick extrajudicial resolution of disputes also in individual employment matters through informal processes tailored to the needs of the parties. The European Community institutions have made the promotion of mediation and other forms of alternative dispute resolution (ADR) a political priority: The c",{"id":254,"funder":7,"programme":8,"title":255,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":256},"cordis-marie-skłodowska-curie-actions-award-253071","High-level Programming of Heterogeneous Multi-core Computing Systems","Heterogeneous multi-core computing systems become very important for solving computational problems because of increased processing power they deliver and better energy efficiency. However, even experienced high performance programmers find it a challenge to fully exploit their potential due to the novelty and variety of available architectures. What's more, currently used programming languages, compilers and software development techniques are not adequate for programming of the new kind of sys",{"id":258,"funder":7,"programme":8,"title":259,"piName":10,"institution":202,"country":168,"year":13,"amount":10,"abstract":260},"cordis-marie-skłodowska-curie-actions-award-252657","Towards a dynamic institutional theory of entrepreneurship: How national institutions shape the triggers, timing, and types of entrepreneurial processes in innovation-intensive industries","It is a stylized fact that prospective entrepreneurs differ in how they proceed to found new firms. Interestingly, though, the literature on process-oriented entrepreneurship does not provide a theory on how national institutions influence the behaviour of prospective entrepreneurs. The proposed project seeks to close this gap. The analytical framework is derived from the literature on national institutions, including theories on the ‘market based view’, ‘national innovation systems’ and ‘variet",{"id":262,"funder":7,"programme":8,"title":263,"piName":10,"institution":264,"country":90,"year":13,"amount":10,"abstract":265},"cordis-marie-skłodowska-curie-actions-award-252234","Multiscale Charge-Transport Simulation of Organic-Based Materials and Devices","FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA","This project aims at developing innovative multiscale computational tools for tackling charge transport in organics materials (organic crystals, organic thin films, etc.). Based on some combination between first principles calculation and mesoscopic transport approaches, We will investigate charge transport in materials of strong technological interest, at an advanced realistic level. The method will take into account strong electron-phonon coupling and related polaronic states, as well as mater",{"id":267,"funder":7,"programme":8,"title":268,"piName":10,"institution":207,"country":168,"year":13,"amount":10,"abstract":269},"cordis-marie-skłodowska-curie-actions-award-252944","A Plasmonic Interface to Carbon Nanotube Quantum Optics","Since their discovery in 1991, single walled carbon nanotubes (SWNTs) have led to a worldwide explosion of research activities due to their outstanding electrical properties. Ten years later, the demonstration of optical emission from semiconducting SWNTs has opened a new field for nano-optics. In terms of quantum information processing, it has been recently shown that SWNTs are promising candidates for single spin quantum computing. Combined with their promising optical properties, this natural",{"id":271,"funder":7,"programme":8,"title":272,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":273},"cordis-marie-skłodowska-curie-actions-award-235092","Single nano-Particle Imaging with Coherent Intense soft X-rays","Ultrafast coherent diffraction using soft and hard X-rays is actually revolutionizing imaging science thanks to new sources recently available. This powerful technique extends standard X-ray diffraction towards imaging of non-crystalline objects and leads actually to a strong impact in physics, chemistry and biology [Miao, Nature 1999]. New ultrashort pulses recently available hold the promise of watching matter evolving with unprecedented time and space resolution. With the SPICIX project we pr",{"id":275,"funder":7,"programme":8,"title":276,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":277},"cordis-marie-skłodowska-curie-actions-award-235091","X-ray Multiple Ionization of Impulsively Aligned Molecules","High-energy and ultrafast soft\u002Fhard X-ray photon beams open new fields in Science with major applications to Biology, Chemistry and Physics. Indeed, a couple of X-ray free-electron lasers (XFEL) are under construction worldwide with the highly exciting objective to perform atomic resolution, 3D movies, by taking a sequence of femtosecond snapshots, of biological molecules such as viruses, proteins etc. Because of the need to capture an image on a single, femtosecond shot, the number of photons p",{"id":279,"funder":7,"programme":8,"title":280,"piName":10,"institution":151,"country":146,"year":13,"amount":10,"abstract":281},"cordis-marie-skłodowska-curie-actions-award-252730","Development of a unified speech processing strategy for combined electric and acoustic auditory stimulation","Cochlear implants (CIs) can restore speech perception of deaf subjects by electrical stimulation of the auditory nerve. Because CI users sometimes perform better than severely hearing impaired subjects with a hearing aid (HA), implantation criteria are changing, leading to a steeply growing population of patients with a CI in one ear and residual hearing, used with a HA, in the other. This is called bimodal stimulation. Currently more than half of all newly implanted patients have residual heari",{"id":283,"funder":7,"programme":8,"title":284,"piName":10,"institution":157,"country":97,"year":13,"amount":285,"abstract":286},"cordis-marie-skłodowska-curie-actions-award-253181","The origin of excess charge at the water\u002Fhydrophobic interfaces","€216,782","The main purpose of this proposal is the theoretical investigation of salt adsorption process at the interface of water\u002Fhydrophobic substrates taking into account impurities, dissolved gases using thermodynamically consistent force fields for ions by molecular dynamics methods. Most hydrophobic polymer materials without any functional and reactive surface groups develops a substantial negative charge at the interface of water-hydrophobic substrate. Source of this excess charge is not determined ",{"id":288,"funder":7,"programme":8,"title":289,"piName":10,"institution":162,"country":79,"year":13,"amount":10,"abstract":290},"cordis-marie-skłodowska-curie-actions-award-253166","Septin organization by multiparameter photoactivated localization microscopy","The septins are a conserved family of GTPases that interact with membranes and the cytoskeleton. Several different septin molecules combine into nonpolar dimeric rods. These rods are thought to assemble end-over-end into higher order structures that orchestrate complex cellular events at the interface of the cytoskeleton and the plasma membrane. In this way, septin complexes organize the cleavage furrow in dividing cells, serve as a corset to maintain cell shape in cell motility, engulf invading",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":294},"cordis-marie-skłodowska-curie-actions-award-255227","Special voice transforms and applications","The general goal of this project is to study the properties of the voice transforms generated by the representations of a given locally compact topological group, to reveal the details and understand the mathematical principles that govern the approximation of functions using discrete frames and wavelets, Zernike functions, spherical functions, construction of multiresolution decompositions. Applications of these processes will be considered. In the theoretical analysis we will focus on particul",{"id":296,"funder":7,"programme":8,"title":297,"piName":10,"institution":162,"country":79,"year":13,"amount":298,"abstract":299},"cordis-marie-skłodowska-curie-actions-award-254407","RHeophysics and Energy of mAgmas","€250,142","To understand dynamic earth processes it is necessary to first understand how magmas flow. Volcanology, geodynamics and planetary sciences all need to know at which stresses magma will behave in a ductile or brittle manner and, even more importantly, the range of the transitional brittle-ductile field.With RHEA we aim to separate the stable from the metastable flowing field of crystal bearing melts and estimate the onset of brittle behavior. This question will be addressed by investigating exper",{"id":301,"funder":7,"programme":8,"title":302,"piName":10,"institution":145,"country":146,"year":13,"amount":10,"abstract":303},"cordis-marie-skłodowska-curie-actions-award-252839","Sustainable European Community Biofuel Industries and Systems (SECURE)","The uncertainty of food and fuel supplies providing a lower carbon future presents an absolute requirement for humankind to develop efficient and sustainable agricultural production systems. However, research has suggested that current European biofuel development and agricultural sustainability criteria may increase both greenhouse gas (GHG) emissions and indirect global land use impacts. These concerns have resulted in cautious development of biofuel crops. The Applicant for the SECURE project",{"id":305,"funder":7,"programme":8,"title":306,"piName":10,"institution":132,"country":133,"year":13,"amount":10,"abstract":307},"cordis-marie-skłodowska-curie-actions-award-251897","Crenarchaeota ecology and nutrient utilization in the subsurface ocean (CAENEUS)","Over the past 10 years, it become apparent that Crenarchaeota are not only striving in some extreme environments but that they are ubiquitously present in the aquatic and terrestrial environment including the oceanic water column. In the pelagic realm of the ocean, their relative contribution to the total prokaryotic abundance increases with depth. It has been shown that the mesophilic Marine Crenarchaeota Group I (MCGI) live chemoautotrophically, fixing carbon dioxide as carbon source and using",{"id":309,"funder":7,"programme":8,"title":310,"piName":10,"institution":177,"country":168,"year":13,"amount":10,"abstract":311},"cordis-marie-skłodowska-curie-actions-award-254419","Cognitive and neural representations of action in temporally coordinated behaviour","Many common behaviours such as moving a table, rowing a boat, and producing music require individual performers to coordinate their actions. Researchers have only begun to investigate the mechanisms of perception, action, and cognition that support these types of joint action (Galantucci and Sebanz, 2009). It has recently been suggested that the activation of mental representations of others’ actions may underlie successful joint action (Sebanz and Knoblich, 2009). However, it has also been argu",{"id":313,"funder":7,"programme":8,"title":314,"piName":10,"institution":315,"country":63,"year":13,"amount":10,"abstract":316},"cordis-marie-skłodowska-curie-actions-award-254339","Coupled Polyoxometalate – Hydrogenase Catalysts for Photocatalytic Water Splitting","UNIVERSITY OF EAST ANGLIA","Alternatives to fossil fuels are of rapidly increasing importance, driven by concerns over energy security, cost, and global warming. In response to these concerns, the EU has set the target of obtaining 20% of all energy from renewable sources by 2020. A key challenge in renewable energy is finding an efficient way to convert plentiful solar energy into a source of chemical energy which can be stored, used for applications such as transportation, and consumed without releasing carbon dioxide – ",{"id":318,"funder":7,"programme":8,"title":319,"piName":10,"institution":162,"country":79,"year":13,"amount":10,"abstract":320},"cordis-marie-skłodowska-curie-actions-award-252284","Innovative Control, Identification and Estimation Methodologies for Sustainable Energy Technologies","The aim of this project is to boost the knowledge, expertise and international contact-network of the young outgoing researcher in the field of systems and control, in order to foster his career and to support him in the development of stable, high-quality research and technology transfer activities at the return host, thus contributing to strengthen the research and development system at local, national and European levels. This aim will be pursued primarily via a structured three-years long pr",{"id":322,"funder":7,"programme":8,"title":323,"piName":10,"institution":151,"country":146,"year":13,"amount":324,"abstract":325},"cordis-marie-skłodowska-curie-actions-award-255264","Calcium Propagation in Atrial Fibrillation","€166,800","Synchronized release of Ca2+ from the internal Ca2+ store of cardiac myocytes, the sarcoplasmic reticulum, is essential for a normal heart beat. This is obtained through a sophisticated subcellular organization, the dyad. In dyads, a cluster of release channels in the sarcoplasmic reticulum, ryanodine receptors or RyRs, face Ca2+ channels in the cell membrane, the dihydropyrydine receptors or DHPRs. DHPRs provide the Ca2+ influx that triggers opening of RyR. Ca2+ release can also propagate betwe",{"id":327,"funder":7,"programme":8,"title":328,"piName":10,"institution":329,"country":97,"year":13,"amount":10,"abstract":330},"cordis-marie-skłodowska-curie-actions-award-254498","Plasmonic Biosensors based on nanometric optical Resonators integrated with point-light-sources for label free detection of DNA","UNIVERSITAET HAMBURG","The objective of this project is to study the confinement of light in nanometric apertures in a metal film, the change of the transmission properties for very small changes in the refractive index inside the holes, and the subsequent development and fabrication of a device that serves to visualize singe DNA molecules, stretched in a channel and assembled into the nanohles, withouth fluorescent markers. For this, during the first stage (2 years in Berkeley), the fellow will study theoretically th",{"id":332,"funder":7,"programme":8,"title":333,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":334},"cordis-marie-skłodowska-curie-actions-award-235625","Appearance in Action: The interplay of perception and action as revealed by attention-related changes in phenomenological appearance","Perception and motor control act in concert to suit our behaviour to current needs. Most research on the interplay of perception and motor control has examined how sensory input is transformed into movement generation. Recent psychophysical and physiological evidence, however, shows that the generation of movements has considerable impact on perception. Most prominently, these interactions have been documented for vision and eye movements, whereas considerably less is known about the mutual depe",{"id":336,"funder":7,"programme":8,"title":337,"piName":10,"institution":202,"country":168,"year":13,"amount":10,"abstract":338},"cordis-marie-skłodowska-curie-actions-award-253911","Argumentation Strategies","Important aspects of everyday life (e.g. healthcare, commerce, law) increasingly rely on networks of distributed but co-operating computer systems. An understanding of negotiation, joint decision making and control of private information in such systems has therefore become a key challenge for computer science. My work will address this challenge by creating a theoretical foundation with which systems with conflicting information, goals and assumptions can jointly decide how to act by exchanging",{"id":340,"funder":7,"programme":8,"title":341,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":342},"cordis-marie-skłodowska-curie-actions-award-254126","Spin transport and dynamics in silicon-germanium islands","This project is centered on spin-dependent electronic transport and spin dynamics in self-assembled SiGe islands, directed at the development of semiconductor spintronic devices. In spite of its promising properties, SiGe remains a largely unexplored system for this purpose. The proposed project is further motivated and supported by an existing experience in the host group, which has recently succeeded in the realization of the first electronic devices based on individual SiGe quantum dots (QDs)",{"id":344,"funder":7,"programme":8,"title":345,"piName":10,"institution":346,"country":347,"year":13,"amount":10,"abstract":348},"cordis-marie-skłodowska-curie-actions-award-253924","Method of Osteo-fracture Study through Automatic Identification and Classification: biomechanical analysis of bone trabecular structure","EREVNITIKO PANEPISTIMIAKO INSTITOUTO SYSTIMATON EPIKOINONION KAI YPOLOGISTON","EL","Bone fractures represent a major health problem in the increasingly elder population. The correct prediction of bone fracture risk in bone disease, e.g. osteoporosis, is a mandatory issue for the prevention of traumatic events and related medical efforts. The assessment of the fracture risk is based on the clinical evaluation of bone mineral density, but with an estimation error ranging from 20% to 40%. Trabecular structure is known to play an important role in the mechanical behaviour of bone, ",{"id":350,"funder":7,"programme":8,"title":351,"piName":10,"institution":151,"country":146,"year":13,"amount":352,"abstract":353},"cordis-marie-skłodowska-curie-actions-award-254243","A View from Heaven. Exploring the Potential of Remote Sensing Techniques to Study Spatial Patterns of Monastic Habitation on the East Bank of the Nile in Middle Egypt","€220,500","Early Egyptian monasticism played a defining role in the establishment of monastic life in Europe. However, our understanding of the history of the formation and organization of monastic life in Egypt itself is incomplete. Whereas monastic centres in northern and southern Egypt are being extensively studied, the important region of Middle Egypt has scarcely received scholarly attention. From AD 300-800, this area had a thriving Christian life and a large number of monastic settlements. On the ea",{"id":355,"funder":7,"programme":8,"title":356,"piName":10,"institution":207,"country":168,"year":13,"amount":10,"abstract":357},"cordis-marie-skłodowska-curie-actions-award-253243","Nanowires for single photon detection and spin memory devices","The ultimate limit in the miniaturization of electronics and photonics is at the nanometer scale. Here the signal level can be controlled at the fundamental level of a single electron and a single photon. These limits are actively being pursued for scientific interest with possible applications in the area of quantum information processing and communication. We propose novel devices aimed at single photon detection and single spin memory using nanowires. The basic building block is a III-V quant",{"id":359,"funder":7,"programme":8,"title":360,"piName":10,"institution":202,"country":168,"year":13,"amount":10,"abstract":361},"cordis-marie-skłodowska-curie-actions-award-237643","Role of siRNA-mediated DNA methylation in the root stem cell niche","Stem cells are undifferentiated cells that can give rise to different cell types in multicellular organisms. Plant and animal stem cells are usually not specified by the same subset of genes, even though the niche organizations are very similar. The Retinoblastoma (Rb) protein and its plant homologue RETINOBLASTOMA-RELATED (RBR) in stem cell identity however constitutes a possible common pathway in both kingdoms (1). We want to further explore possible similarities in stem cell control, so we fo",{"id":363,"funder":7,"programme":8,"title":364,"piName":10,"institution":365,"country":97,"year":13,"amount":366,"abstract":367},"cordis-marie-skłodowska-curie-actions-award-254331","Solid-state Quantum Optical Devices","TECHNISCHE UNIVERSITAET MUENCHEN","€168,969","Quantum Dots in Microcavities offer a unique laboratory to investigate quantum physics. The state of the art has recently achieved the so-called strong coupling where coherent quantum interactions dominate the system dynamics. Nonlinear effects of a quantum character have been shown under coherent excitation (e.g., photon blockade). An appealing framework is incoherent excitation, where the device undergoes its intrinsic dynamics in a steady state. In this case, many issues remain unresolved. On",{"id":369,"funder":7,"programme":8,"title":370,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":371},"cordis-marie-skłodowska-curie-actions-award-251809","POPULATION DYNAMICS OF MEDITERRANEAN WATERBIRDS AND THEIR DEMOGRAPHIC AND BEHAVIOURAL RESPONSES TO GLOBAL CHANGE","Coastal, wetland, island and marine ecosystems have been largely modified during the last century making them especially vulnerable to global change threats. In the Mediterranean basin over the last few decades, major socio-economic changes have increased the negative impact of human activity, mainly along the coasts, pushing many endemic species on the edge of extinction. The ability of populations to respond to environmental changes, and their speed, will depend on the existence of individual ",{"id":373,"funder":7,"programme":8,"title":374,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":375},"cordis-marie-skłodowska-curie-actions-award-250590","Lyman-alpha Radiation Transfer simulations to prepare and analyze MUSE observations of distant galaxies","MUSE is a second generation instrument for the ESO-VLT being built in Lyon. This integral field spectrograph is planned to start observing in autumn 2012. One of the major goals of MUSE is to detect thousands of high redshift galaxies thanks to their Lyman-alpha emission. MCLya is a 3D Lyman-alpha radiation transfer code developed by the applicant. It has been used to fit a small sample of observed Lyman-alpha lines from high redshift galaxies, constraining the gas and dust content and the star ",{"id":377,"funder":7,"programme":8,"title":378,"piName":10,"institution":127,"country":46,"year":13,"amount":10,"abstract":379},"cordis-marie-skłodowska-curie-actions-award-235759","Perturbative Approaches to Gravitational Instability and Lensing in Cosmology","Observations of the large-scale structure of the Universe are one of the pillar supporting the standard cosmological model. Coming surveys are expected to shed new light on its still missing parts, such as the nature of dark energy and cosmic acceleration. They also can provide increasingly stringent tests of the inflationary paradigm offering a window on the high-energy physics that determined the early stages of the Universe. The unprecedented precision of future large-scale structure surveys ",{"id":381,"funder":7,"programme":8,"title":382,"piName":10,"institution":383,"country":384,"year":13,"amount":385,"abstract":386},"cordis-marie-skłodowska-curie-actions-award-254573","DNA sensor in polymer photonic crystal band-edge lasers with integrated nanochannels","DANMARKS TEKNISKE UNIVERSITET","DK","€207,629","The proposed project will develop a polymer-based optofluidic lab-on-a-chip device to study the physical dynamics of label-free DNA molecules. DNA contains the complete genetic code of an organism, yet it is the interaction of DNA with other molecular species that determine how that code is interpreted. Moreover, it has been suggested that there are other factors beyond the genomic sequence that are involved in an organism’s complexity. Subsequently, this project will study the physical dynamics",{"id":388,"funder":7,"programme":8,"title":389,"piName":10,"institution":390,"country":347,"year":13,"amount":10,"abstract":391},"cordis-marie-skłodowska-curie-actions-award-235926","String theory","EREVNITIKO PANEPISTIMIAKO INSTITOUTO THEORITIKIS KAI YPOLOGISTIKIS FYSIKIS","Recently a new class of three dimensional N=8 and N=6 superconformal theory has been discovered. These theories are defined by a classical action and have a (discrete) parameter k that can serve as a coupling constant. Taking k large (coupling small) one can use perturbation Feynman diagram techniques. The theory for k=1 is particularly interesting as it is conjectured to be the N=8 theory living on coincident M2 branes (membranes). Membranes are extended objects in M-theory, and some believe th",{"id":393,"funder":7,"programme":8,"title":394,"piName":10,"institution":202,"country":168,"year":13,"amount":10,"abstract":395},"cordis-marie-skłodowska-curie-actions-award-254446","Multisensory integration in the cognitive representation of space","Remembering the position of objects is crucial for the navigation through daily-life environments like buildings and cities. In spite of the fact that environmental sensory information is inherently multimodal, the research on object location memory is still almost exclusively focused on the visual domain. In this Fellowship project, we propose an extensive analysis of the cognitive mechanisms and brain correlates of object location memory for non-visual and multisensory objects. In a series of ",{"id":397,"funder":7,"programme":8,"title":398,"piName":10,"institution":399,"country":97,"year":13,"amount":10,"abstract":400},"cordis-marie-skłodowska-curie-actions-award-234974","Unraveling key abiotic and biotic interactions for sustainable anaerobic biotransformation of chlorinated solvents in groundwater","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","Chlorinated solvents are potential carcinogens frequently found in groundwater and are classified as priority pollutants. Anaerobic biotransformation of these compounds to non-toxic ethene via reductive dechlorationation is carried out by microorganisms living in consortia. Bioaugmentation – the addition of active microbial cultures to a contaminated site – is a low-cost and potentially highly effective remediation alternative, particularly for chlorinated solvents, where dechlorination is carri",{"id":402,"funder":7,"programme":8,"title":403,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":404},"cordis-marie-skłodowska-curie-actions-award-237835","In Vivo Observation of Transcriptional Regulation in Bacilli by Fluorescence Correlation Spectroscopy","This application proposes the study of transcriptional regulation in Bacillus subtilis by direct, in vivo, observation using state-of-the-art two-photon fluorescence correlation spectroscopy. The project involves the study of two transcriptional repressors from B. subtilis, CggR and CcpN. Much work has been done in vitro on CggR and CcpN (Zorrilla et al, 2007a; Zorrilla et al, 2007b; Zorrilla et al, 2008a; Zorrilla et al, 2008b) since their discovery in the sequencing of the B. subtilis genome(K",{"id":406,"funder":7,"programme":8,"title":407,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":408},"cordis-marie-skłodowska-curie-actions-award-252874","Exploring Structure-Function Relationship of Enzymes at Single Molecule Level: Fluorescence and Force Spectroscopy","The relation between structure and functions is a central topic in enzymology. I propose to study that question at the single molecule level employing a novel optical and force spectroscopy. The enzyme will be linked to a glass surface employing PEG-Biotin-Streptavidin interaction. The location of a single enzyme will be determined by a dye attached to it. The substrate of the reaction, while being non-fluorescent, will be chosen so that its enzymatic reaction product is fluorescent. The time sp",{"id":410,"funder":7,"programme":8,"title":411,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":412},"cordis-marie-skłodowska-curie-actions-award-252122","Analytic approaches to planar growth processes","Many important phenomena reveal stochastic geometrical objects and shapes. Among them are fluctuating domain boundaries in statistical mechanics, growing patterns in non-equilibrium processes, and fluctuating surfaces studied in random matrix theory. These geometrical objects naturally arise in the theory of 2D growth processes, disordered systems and random media. In many interesting cases they are fractal in nature. The project focuses on a wide class of processes involving stochastic geometry",{"id":414,"funder":7,"programme":8,"title":415,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":416},"cordis-marie-skłodowska-curie-actions-award-252086","Measuring and modelling nitrous acid (HONO) emissions at Dome C, Antarctica","The goal of this research project is to understand the nitrous acid (HONO or HNO2) emissions from snow in Antarctica and their contributions to the oxidative capacity of the Antarctic atmosphere. Nitrous acid is an important atmospheric trace gas. Upon photo-dissociation, it forms hydroxyl radical (OH) and nitrogen monoxide (NO). It therefore enters both the HOx (OH + HO2) and NOx (NO + NO2) budgets which are key budgets when considering the oxidative capacity of the atmosphere. In Antarctica, t",{"id":418,"funder":7,"programme":8,"title":419,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":420},"cordis-marie-skłodowska-curie-actions-award-251871","Physics beyond the Standard Model: establishing footprints in the light of data","The Large Hadron Collider will be the first accelerator to directly and fully explore the Fermi energy scale, thereby offering the opportunity of a real understanding of its dynamics. The relevance of this task is only comparable with the challenge of extracting new information from the LHC data and of finding the correct signal interpretation out of many theoretical possibilities. In fact, existing data already provide important hints on likely and less likely new physics models and constrain m",{"id":422,"funder":7,"programme":8,"title":423,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":424},"cordis-marie-skłodowska-curie-actions-award-236295","SEABIRDS, TUNA, CLIMATE CHANGE – FUNCTIONAL RELATIONSHIPS IN THE TROPICAL INDIAN OCEAN AND SUSTAINABLE USE OF ITS RESOURCES","The world is facing strong anthropogenic impacts by climate change and intensive exploitation of its natural resources. This will inevitably have profound consequences for ecological processes. Tropical Oceans have a substantial ecological significance but there is only little knowledge on their functioning. This knowledge, however, is crucial to evaluate effects of climate change and resource exploitation on these ecosystems. In the proposed project, the fellow will investigate these issues in ",{"id":426,"funder":7,"programme":8,"title":427,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":428},"cordis-marie-skłodowska-curie-actions-award-237194","Synchrony among Neighbor Neurons in Cerebellum","The scientific objective of the proposal is to investigate the role of synchronous activity in local neuronal networks of the Cerebellum in motor coordination and learning. Specifically, we will test whether synchronous Complex Spike activity in neighboring Purkinje cells encodes errors guiding motor adaptation during locomotion in mice. This investigation is made possible by a novel fluorescence imaging technique developed in the Schnitzer laboratory (outgoing host at Stanford University): calc",{"id":430,"funder":7,"programme":8,"title":431,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":432},"cordis-marie-skłodowska-curie-actions-award-237228","Tree Range Evolution under Climate Change","Ongoing global warming impacts species' biology, with some species showing population extinction, others displacing their distributional range and\u002For modify their phenology, either through phenotypic plasticity or genetic modifications. This two-year project aims at evaluating how changing climatic conditions will modify the distributional range of tree species, taking adaptation into account. More specifically, the following questions will be addressed: (1) under which conditions will distribut",{"id":434,"funder":7,"programme":8,"title":435,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":436},"cordis-marie-skłodowska-curie-actions-award-235720","Biochemical characterization of Arabidopsis Fe uptake transporter IRT1","Iron is an essential nutrient. It is involved in a great variety of biological processes, such as photosynthesis or the oxidative respiration. Iron deficiency is a factor limiting crop production, and the most important dietary deficiency in humans. In order to address these problems, plant iron uptake has been studied with detail. As a result, metal transporters of the ZIP family have been identified as the main responsibles for iron uptake from soil in plants, with the exception of some grasse",{"id":438,"funder":7,"programme":8,"title":439,"piName":10,"institution":440,"country":90,"year":13,"amount":441,"abstract":442},"cordis-marie-skłodowska-curie-actions-award-253883","Interaction Dynamics and Autonomy in Social Cognition","UNIVERSIDAD DEL PAIS VASCO\u002F EUSKAL HERRIKO UNIBERTSITATEA","€147,217","Social cognition is concerned with how cognitive agents understand and navigate the social world. Most social cognition research today – whether in cognitive science, psychology or neuroscience – focuses only on the individual mechanisms needed to figure out others’ mental states. But this view over-emphasises the individual and gives social dynamics no more than a contextual role. However, there is an alternative: the process of interaction itself may be crucial to social cognition. To articula",{"id":444,"funder":7,"programme":8,"title":445,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":446},"cordis-marie-skłodowska-curie-actions-award-237621","Dissecting the new “platform-binding site” on the bacterial ribosome. Role of particular ribosomal proteins in regulating translation initiation in bacteria","Recent X-ray crystallographic and cryo-electron microscopy data indicate that structured mRNAs bind to the bacterial ribosome at an early step of translation initiation, to a newly characterised ribosomal site located at the “platform” of the small ribosomal subunit (the “platform-binding” site or PBS). In a second step, the mRNAs are supposed to unfold and to migrate to the P-site to interact with the initiator tRNA. The proposal aims at dissecting the role of ribosomal proteins situated at the",{"id":448,"funder":7,"programme":8,"title":449,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":451},"cordis-marie-skłodowska-curie-actions-award-234845","Identities in Transition: Understanding ethnicity and its intersection with gender, religious affiliation and socio-economic position in comparative perspective","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","This project investigates ethnic identity and its intersection with gender, religious affiliation and socio-economic position in comparative perspective. It will explore how the identity of members of minority ethnic groups is shaped and re-formed over generations, including being reformulated as religious identity. It will examine how identification is mediated by gender. The research will take a comparative approach investigating the role of national context in ethnic and religious identificat",{"id":453,"funder":7,"programme":8,"title":454,"piName":10,"institution":450,"country":90,"year":13,"amount":455,"abstract":456},"cordis-marie-skłodowska-curie-actions-award-253032","Innovative organic\u002Finorganic hybrid materials for multifunctional catalysis","€212,054","Organic-inorganic hybrids are of great interest because they combine the advantage of inorganic solids (high mechanical, thermal and structural stability) and organic molecules (flexibility and functionality). The heterogeneous catalysts are limited in the nature of the active sites and thus the scope of reactions that they can accomplish, whilst the organic molecules can catalyse a larger variety of reactions but suffer from their inability to be recycled. The goal is to use the organic moiety ",{"id":458,"funder":7,"programme":8,"title":459,"piName":10,"institution":450,"country":90,"year":13,"amount":460,"abstract":461},"cordis-marie-skłodowska-curie-actions-award-253445","Novel sunlight-active nanoarquitectures for environmental and human health protection studied with a new multi-technique methodology at operando conditions","€154,417","The main goal of this project is to develop novel environmental friendly photocatalysts. The work would follow three principal directions: 1.Synthesis of novel heterogeneous TiO2 catalysts 2.Identification of the reaction mechanism 3.Applications in environmental\u002Fhuman-health problems, such as priority organic pollutants and harmful microorganisms in gas and liquid phase. Many of the photocatalytic reactions reported so far are activated by UV light and do not exploit the “green” potential of th",{"id":463,"funder":7,"programme":8,"title":464,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":465},"cordis-marie-skłodowska-curie-actions-award-236716","Modelling the self-assembly of polymers in solution","This project focuses on theoretical studies of polymers (long chain molecules) dissolved in a liquid. If a section of each molecule is incompatible with the solvent, the polymers may self-assemble into a range of structures in order to minimise the contact of this section with the liquid. This project will consider the self-assembly of polymers into vesicles (hollow spheres), which resemble those seen in cells and can also be used to encapsulate and deliver drugs. Novel polymers will be designed",{"id":467,"funder":7,"programme":8,"title":468,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":469},"cordis-marie-skłodowska-curie-actions-award-251812","Collective Action and Memory in the French Environmental Movement","This project investigates transformations in environmental protest strategies since the 1970s, placing them in the context of changing configurations of state power and legal and political norms. Undertaken within the CRAPE research centre on political mobilisation at the IEP in Rennes, the project focuses on the opposition to the construction of nuclear power plants in north-west France, comparing current mobilisations with the widespread opposition to reactor siting in the late the 1970s and e",{"id":471,"funder":7,"programme":8,"title":472,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":473},"cordis-marie-skłodowska-curie-actions-award-252757","Nanocontacted Thin Molecular Films for Spintronics","This proposal is placed in the area of molecular spintronics, a multidisciplinary area of knowledge in between molecular magnetism, molecular electronics and surface science and deals with the integration of molecular materials in spintronic devices. The weak spin–orbit coupling and hyperfine interactions found in organic materials, along with its ease of processability and tunability, make molecules became serious candidates to substitute traditional metals and inorganic semiconductors or insul",{"id":475,"funder":7,"programme":8,"title":476,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":477},"cordis-marie-skłodowska-curie-actions-award-254804","Towards the deterministic modelling of immiscible flows in porous media: Mesoscale simulations and Experimental verification","Immiscible two-phase flow in macroporous materials is a subject of significant applied and scientific interest. It is encountered in a series of environmental and energy-related processes such as soil remediation, enhanced oil recovery from fractured petroleum reservoirs, geothermal processes, CO2 sequestration etc. The study and optimization of such processes requires the development of rigorous modelling tools that successfully capture the physics of the flow process at the pore scale, and the",{"id":479,"funder":7,"programme":8,"title":480,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":481},"cordis-marie-skłodowska-curie-actions-award-252811","Evolution Meets MAcroecology - integrating rapid adaptation into predictions of future plant species' ranges","The current rate of anthropogenic climate change is predicted to be unmatched in earth's history. The associated potential loss of biodiversity and ecosystem function is one of the most critical issues our society is facing. Thus, a major aim of global change research is the development of reliable predictions on future geographic distributions of species, communities and functional diversity. These predictions allow to assess the impacts of climatic changes on ecosystem goods and services, to d",{"id":483,"funder":7,"programme":8,"title":484,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":485},"cordis-marie-skłodowska-curie-actions-award-254456","Defects in two dimensional field theories","The aim of this proposal is to study aspects of one dimensional defects in two dimensional field theories. One aspect is the relation of a certain class of defects, Wilson loops, to the integrable structure of Wess-Zumino-Witten models and coset models. Through the use of quantum groups, it should be possilbe to quantize these classical defects and describe exactly in a universal way a large class of boundary renormalization group flows of conformal field theories. A second aspect is the relatio",{"id":487,"funder":7,"programme":8,"title":488,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":489},"cordis-marie-skłodowska-curie-actions-award-255662","Electron paramagnetic resonance as a probe for extended interfaces in nanomaterials","Ferroelectric materials are considered for applications in telecom devices opera ting at high frequency such as phase shifters, antennas or resonators. With the increasing requirements for miniaturization and low cost electronics, the market is nowadays widely turned to agile components and there is in particular a strong competition for the search of new materials. The best candidates for such applications are ferroelectric (FE) materials. Their distinctive advantage among all other materials i",{"id":491,"funder":7,"programme":8,"title":492,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":493},"cordis-marie-skłodowska-curie-actions-award-251887","Current-induced domain wall motion in magnetic nanostrips","The recent progress in the fabrication and direct synthesis of laterally confined structures, thanks to lithography techniques, has given rise to renewed interest in understanding the interaction between spin-polarized current and magnetic domain walls (DWs), because of it is a key technology for the future spintronics. Although there are several possible ways in which current can interact with magnetic domains, the most interesting interaction is that in which spin angular momentum transferred ",{"id":495,"funder":7,"programme":8,"title":496,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":497},"cordis-marie-skłodowska-curie-actions-award-235861","Seismic Signature of Plumes and the Heat Budget of Earth’s Mantle: Bridging the Gap Between Theoretical High-Performance Computations and Observations","The long-lived paradox between geochemical arguments for two compositionally distinct mantle reservoirs and geophysical evidence for extensive mass exchange between upper and lower mantle has still not been resolved in a manner to reach consensus. Recently, finite frequency tomography has produced images of large lower mantle plumes, which potentially carry a significant amount of heat through the mantle. This raises the prospect that the dynamic role of these plumes is larger than inferred clas",{"id":499,"funder":7,"programme":8,"title":500,"piName":10,"institution":501,"country":46,"year":13,"amount":10,"abstract":502},"cordis-marie-skłodowska-curie-actions-award-252542","Fluid Mechanics of Flagellar Propulsion","UNIVERSITE D'AIX MARSEILLE","The locomotion of microorganisms in fluids is a theme of major importance in biology. It affects many processes such as mammalian reproduction, the marine life ecosystem, and the dynamics of bacterial infection. Locomotion is typically achieved by the periodic deformation of flagella (short and flexible organelles) that drive the fluid motion around the microorganisms, and generate propulsive forces. The shape of the flagella is, in turn, affected by the fluid dynamics forces generated by the or",{"id":504,"funder":7,"programme":8,"title":505,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":507},"cordis-marie-skłodowska-curie-actions-award-235353","International criminal law as a tool for enhancing the protection of cultural heritage","EUROPEAN UNIVERSITY INSTITUTE","International law provides both for State responsibility and individual criminal liability for the destruction of cultural property in the event of armed conflict. In this respect, relevant provisions are incorporated in the Statutes of the International Criminal Tribunal for the Former Yugoslavia (ICTY) and of the International Criminal Court (ICC). On the other hand, there are no binding international provisions criminalizing attacks against cultural property in times of peace. The only releva",{"id":509,"funder":7,"programme":8,"title":510,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":511},"cordis-marie-skłodowska-curie-actions-award-235199","Walking Old Paths in New Shoes: Individual Trajectories to Retirement and the Welfare State in Austria and Germany","This project carries out a comparative investigation of retirement behaviour in Austria and Germany. Drawing on the theoretical concept of ‘pathways to retirement’ (Kohli & Rein 1991) it examines individual trajectories leading to labour market exit both through policy-analysis as well as empirically. The project proposes an interdisciplinary analytical approach and mix of methods. The empirical bases are process-produced work history data spanning over 30 years (linked employer-employee data). ",{"id":513,"funder":7,"programme":8,"title":514,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":515},"cordis-marie-skłodowska-curie-actions-award-254371","Landslides, floods and erosion: new insights from event-based field measurements in the Southern Alps of New-Zealand and stochastic 2D numerical modeling of long-term landscape evolution","Long-term erosion of mountain belts is driven by discrete landsliding events that deliver sediment to rivers, and flood events that transport sediment away and incise bedrock. Landsliding and flooding events obey different frequency-magnitude distributions, are partially correlated (e.g., storms trigger landsliding and flooding, earthquakes only trigger landsliding), and interact along the drainage network to generate a complex spatio-temporal response still poorly understood at the event scale ",{"id":517,"funder":7,"programme":8,"title":518,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":519},"cordis-marie-skłodowska-curie-actions-award-235461","Civil society and the mobilization of European human rights: Minorities and Immigrants in the Strasbourg Court","LEGAPOLIS seeks to understand and explain how by interpreting the Convention the European Court of Human Rights has over time expanded and transformed from a primarily political and institutionally weak international regime into a binding legal system of transnational rights review. It explores in a systematic way the causes and consequences of its expansion by specifically focusing on the Court’s burgeoning case law pertaining to minorities, immigrants and asylum seekers. Through a series of ca",{"id":521,"funder":7,"programme":8,"title":522,"piName":10,"institution":523,"country":524,"year":13,"amount":525,"abstract":526},"cordis-marie-skłodowska-curie-actions-award-254127","Role of prolyl oligopeptidase in neuroinflammation and novel therapeutic use of specific POP inhibitors","HELSINGIN YLIOPISTO","FI","€178,088","Neurodegenerative diseases present a broad range of phenotypic symptoms derived from deterioration of different brain functions, such as controlling movements, processing information or memory. All those symptoms are caused by the loss of specific neurons controlling those processes. All neurodegenerative diseases result from damage of neurons or their myelin sheaths that eventually will lead to dysfunction and disabilities. The neuroinflammatory hypothesis of neurodegenerative diseases proposes",{"id":528,"funder":7,"programme":8,"title":529,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":530},"cordis-marie-skłodowska-curie-actions-award-251877","Exchange Rates and Fundamentals","This proposal builds upon the seminal work of Engel & West (JPE, 2005) on the relationship between FX rates (FXRs) & fundamentals (FMs). They deal with the long-standing puzzle in international economics, which is the difficulty of linking floating FXRs to macroeconomic FMs. In this project, we take a new line of attack on the question of co-movement between FXRs & FMs as well as between FXRs. We work with the class of asset-pricing models of Engel & West (EW). We attempt to empirically verify t",{"id":532,"funder":7,"programme":8,"title":533,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":535},"cordis-marie-skłodowska-curie-actions-award-254747","Regulation of Rho proteins by mechanical forces in the vascular system","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","As molecular links between mechanosensors and the regulation of cellular processes Rho proteins have a critical position in mechanotransduction. Interestingly during cardiovascular disease (CVD) involving aberrant hemodynamic forces Rho proteins are activated. How do mechanical forces regulate Rho proteins? How do they contribute to the mechanical adaptation of the cell? And How is this mechanism altered during CVD? To answer these questions we have designed a proposal in two phases with interdi",{"id":537,"funder":7,"programme":8,"title":538,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":539},"cordis-marie-skłodowska-curie-actions-award-253929","Role of Ebf3 in the distribution of Cajal-Retzius cells","Cell migration is a fundamental process during mammalian brain development since all neurons migrate to their final location. Cajal-Retzius (CR) cells are transient neurons that control the laminar organization of the cerebral cortex and form a monolayer at its the surface. It has been shown that CR cells are generated by focal sources surrounding the cerebral cortex and disperse on its surface. However, how the monolayer distribution of CR cells is achieved during development and what cell cont",{"id":541,"funder":7,"programme":8,"title":542,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":543},"cordis-marie-skłodowska-curie-actions-award-252665","Real-time decoding of conscious and non-conscious perceptual events in the human brain","The decoding of brain states using machine learning techniques has become a widely used approach in many areas of neuroscience research. The performance of the classifier under different conditions, as well as the by products of the decoding process, can be used to make inferences about how the brain encodes information. Decoding methods are also central to the development of non-invasive brain-computer interfaces (BCI) where decoding is done in real-time. Non-invasive real-time decoding techniq",{"id":545,"funder":7,"programme":8,"title":546,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":547},"cordis-marie-skłodowska-curie-actions-award-252610","Impact of the chromatin environment on the CTG repeat instability involved in myotonic dystrophy type 1","Since the identification of unstable trinucleotide repeats (TNRs) as the genetic cause of human neurological diseases, many studies have tried to unravel the mechanisms of repeat expansion. MSH2 and MSH3, DNA mismatch repair proteins, modify expansion in transgenic mice. Circumstantial evidence suggests that cis-elements surrounding the repeats modulate their instability. However, a detailed analysis of the relationship between chromatin environment and trinucleotide repeat instability is lackin",{"id":549,"funder":7,"programme":8,"title":550,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":551},"cordis-marie-skłodowska-curie-actions-award-251494","METABOLIC EFFECTS OF LEUCINE SUPPLEMENTATION ON THE PREVENTION AND TREATMENT OF DIET-INDUCED OBESITY","Among the branched-chain amino acids, leucine is known to decrease food intake via mTORC1-dependent mechanisms. We now hypothesize that leucine protects against diet-induced obesity (DIO) by having a beneficial effect on inflammation and insulin sensitivity. We postulate that these effects are due to leucine’s ability to affect intracellular pathways that modulate energy balance as well as protein synthesis, inflammation and mitochondrial function. To study leucine’s effects on the development o",{"id":553,"funder":7,"programme":8,"title":554,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":555},"cordis-marie-skłodowska-curie-actions-award-235205","INDIVIDUAL HETEROGENEITY AND THE EVOLUTION OF PHENOTYPIC VARIABILITY","This project aims to extend our understanding of the maintenance and evolution of phenotypic variability, in particular variability in life history parameters. Among individual contributions to population dynamics will be assessed, by investigating variability in age-specific mortality and reproduction. Experiments on bacteria will be used to provide high-quality individual level data that will be analyzed using mathematical models and simulations. The main objective is to explain observed, and ",{"id":557,"funder":7,"programme":8,"title":558,"piName":10,"institution":523,"country":524,"year":13,"amount":10,"abstract":559},"cordis-marie-skłodowska-curie-actions-award-235655","Preparing Complex Nanostructures by Atomic Layer Deposition","During the fellowship, novel, beyond the-state-of-the-art complex nanostructures will be prepared by atomic layer deposition (ALD). ALD is based on successive, alternating surface controlled reactions from the gas phase to produce thin films in the nanometer range with perfect conformality, process controllability and precise control of film thickness. In this project, four complex nanocomposites and nanoreplicas will be prepared: (1) Semiconductor oxide core-shell structures (WO3 nanotube core ",{"id":561,"funder":7,"programme":8,"title":562,"piName":10,"institution":534,"country":46,"year":13,"amount":10,"abstract":563},"cordis-marie-skłodowska-curie-actions-award-254171","Theory and methods for evidence based perinatal health care and policy in cross-national studies","Improving the organisation of healthcare services is one way to contribute to better maternal and infant health. Over the past 10 years, my research at the Epidemiological Research Unit on Perinatal Health and Mother’s and Children’s Health, INSERM U953, has focused on assessing the impact of the organisation of care on the health of babies born very preterm (\u003C32 weeks of gestational age) in France and other European countries and on the effects of the restructuring of obstetric and paediatric h",{"id":565,"funder":7,"programme":8,"title":566,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":567},"cordis-marie-skłodowska-curie-actions-award-254819","BOOKS AND READERS BETWEEN THE IBERIAN AND ITALIAN PENINSULAS TOWARDS AMERICA (SEVILLE AND FLORENCE)","The first aim of my project is to study the development of a new kind of readers in Europe in the Early Modern period, those who were interested in works of humanities (understood as the erudition and fine writing), and the influence of cultural transferences on it. Until this moment, these humanities works have been studied from the perspective of its lenguage, its authors or its bibliographical characteristics, but the questions proposed in this project are different. An interdisciplinary pers",{"id":569,"funder":7,"programme":8,"title":570,"piName":10,"institution":450,"country":90,"year":13,"amount":571,"abstract":572},"cordis-marie-skłodowska-curie-actions-award-255396","New methods of aquatic hyperspectral light field analysis for concurrent characterisation of physical and bio-optical processes at small scales","€161,293","There is a growing concern with the marine environment and societies fear the depletion of fish stocks, pollution and possible impacts of climate change such as the loss of biodiversity. Most of the biological diversity in the ocean relies on the presence of phytoplankton as primary producers and the first element in the oceanic food chain. With over 20,000 known species, the importance of these ubiquitous plants as a food source for the pelagos and as a potential sink of atmospheric carbon have",{"id":574,"funder":7,"programme":8,"title":575,"piName":10,"institution":576,"country":577,"year":13,"amount":10,"abstract":578},"cordis-marie-skłodowska-curie-actions-award-235730","FEM-RBF: A geometrically flexible, efficient numerical solution technique for partial differential equations with mixed regularity","UPPSALA UNIVERSITET","SE","Numerical simulation has become one of the most important tools in science and engineering. The available computer power has been steadily increasing, making it possible to do ever more complex simulations. However, in order to make efficient use of our computers, the state-of-the-art numerical algorithms must also be advanced to a similar degree. In this project, we propose a new hybrid technique designed to address partial differential equations whose solutions are largely smooth, but exhibit ",{"id":580,"funder":7,"programme":8,"title":581,"piName":10,"institution":576,"country":577,"year":13,"amount":10,"abstract":582},"cordis-marie-skłodowska-curie-actions-award-253511","Contradictory phenotypic and genetic sex can lead to great insights into sex chromosome evolution","For the first time the possibility to change certain species sex while maintaining their original sex chromosomes is presented as an excellent opportunity to unravel aspects of sex chromosome evolution. Theory of sex chromosome evolution states that sexually antagonistic genes, i.e. genes that are beneficial to one sex but at the same time harmful to the opposite sex, should often be linked to one of the sex chromosomes. Current knowledge of which genes are responsible for such sexual antagonism",{"id":584,"funder":7,"programme":8,"title":585,"piName":10,"institution":586,"country":347,"year":13,"amount":10,"abstract":587},"cordis-marie-skłodowska-curie-actions-award-255409","Resilience of Opportunistic Networks to Node Misbehaviors","ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON","Whereas there has been considerable work in the DTN community on the design and analysis of different data forwarding algorithms, much less attention has been paid to the associated security and cooperation issues (ref. Section B1.1.1). In particular, there is limited work on the resilience of these schemes to node misbehaviors. Nodes might defer from participating in the data forwarding process, in order to either not spend their (limited) resources for relaying data of no interest to them (sel",{"id":589,"funder":7,"programme":8,"title":590,"piName":10,"institution":576,"country":577,"year":13,"amount":10,"abstract":591},"cordis-marie-skłodowska-curie-actions-award-255363","Understanding the Bioluminescence and Chemiluminescence Mechanisms: the Luciferin-Luciferase Complex and Luminol","As complex processes that they are, the knowledge about the chemiluminescence and bioluminescence phenomena is still being built up. Although much progress was done during the past decades, many mysteries remain unsolved. The mechanism of the complete luciferin-luciferase complex of the firefly is to date not understood in all its details, particularly, the light emitting species is still not conclusively determined. The chemiluminescence mechanism of the luminol molecule is unknown. The aim of ",{"id":593,"funder":7,"programme":8,"title":594,"piName":10,"institution":576,"country":577,"year":13,"amount":10,"abstract":595},"cordis-marie-skłodowska-curie-actions-award-236454","Supersymmetry, supergravity and geometry in particle physics and string theory","The Standard Model of particle physics, which has so far provided a successful description of elementary particles, is believed to be an incomplete theory. New experiments are starting to probe physics beyond the Standard Model. Supersymmetry, supergravity, and string theory are the theoretical tools that are expected to describe the new physics proposing solutions to fundamental problems such as the nature of dark matter, the unification of forces and the formulation of quantum gravity. Moreove",{"id":597,"funder":7,"programme":8,"title":598,"piName":10,"institution":523,"country":524,"year":13,"amount":10,"abstract":599},"cordis-marie-skłodowska-curie-actions-award-253994","“Getting energy from Russia to Europe : Domestic political conditions in the energy-poor transit states of the former USSR and risks to energy transit to the European Union\"","The objective of this project is to develop the synergies between the applicant’s unique expertise on the energy-poor transit states of the Former Soviet Union (FSU), the intellectual and organizational resources of the Aleksanteri Institute as a rising center for Russian and Eastern European energy research, and the applicant’s extensive international academic network with the goal of creating new knowledge on the domestic politics of the energy-poor transit states of the FSU and their effects ",{"id":601,"funder":7,"programme":8,"title":602,"piName":10,"institution":501,"country":46,"year":13,"amount":10,"abstract":603},"cordis-marie-skłodowska-curie-actions-award-252518","GRANARIES AND WAREHOUSES IN NORTH AFRICA AND EGYPT DURING THE ROMAN AGE. TYPOLOGY, BUILDING TECHNIQUES, FUNCTION, PRODUCTIVE CONTEXT","The present project aims at presenting an interdisciplinary way of looking at the history of the African grain in Roman age, in particular from the 1st century BC to the 5th century AD, starting from the data that can be found at archaeological level. The project of starting a new research arises from the lack of a comprehensive study, sufficiently updated and complete, considered all noticeable evidence emerged from the excavations of the past forty years. The present study intends to develop a",{"id":605,"funder":7,"programme":8,"title":606,"piName":10,"institution":501,"country":46,"year":13,"amount":10,"abstract":607},"cordis-marie-skłodowska-curie-actions-award-237339","Development and application of new Nuclear Magnetic Resonance methodologies for structure determination of solid or semi-solid samples","The focus of my research project is the development of new solid-state Nuclear Magnetic Resonance (NMR) methodologies that allow the determination of the structure of solid or semi-solid samples. Materials of this type are central to many interesting biophysical questions but, because they are typically insoluble and non-crystalline, they are not amenable to structure determination by traditional biophysical techniques such as solution-state NMR or single-crystal X-ray diffraction. They may also",{"id":609,"funder":7,"programme":8,"title":610,"piName":10,"institution":576,"country":577,"year":13,"amount":10,"abstract":611},"cordis-marie-skłodowska-curie-actions-award-236501","Evolution of Form and Function on a Unique Eukaryotic Organism (Dictyostelia)","The dictyostelids (social amoebae) are a major group of soil microbes that hover at the borderline of true multicellularity. With the completion of the Dictyostelium discoideum genome in late 2005 and the publication of the first molecular phylogeny in late 2006, Dictyostelia is gaining increasing importance as an evolutionary model system. It is a powerful and unique system for studying the evolution of fundamental eukaryotic cell biology, from cell-cell signalling to the origin and evolution o",{"id":613,"funder":7,"programme":8,"title":614,"piName":10,"institution":501,"country":46,"year":13,"amount":10,"abstract":615},"cordis-marie-skłodowska-curie-actions-award-252132","Archaic and classical Greek Amphoras in north-western Mediterranean area and central Europe: diffusion, origin and contents","The transport amphoras are of great importance for the investigation of the commercial activities in ancient times since they use for the transport of wine, oil, meat, fish, and other perishable organic materials. Moreover, they are tangible traces of the movement of goods and peoples and their intermingling. However, their investigation in Central Europe has not been taken up to the same extent as in the Mediterranean area in Archaic and Classical period (600-400 BC), the time when extensive lo",{"id":617,"funder":7,"programme":8,"title":618,"piName":10,"institution":506,"country":40,"year":13,"amount":10,"abstract":619},"cordis-marie-skłodowska-curie-actions-award-251958","Agencies in the European Union Area of Freedom, Security and Justice: Frontex, Europol and Eurojust","This study concerns the role of agencies (Europol, Eurojust and Frontex) in the European Union’s (EU) Area of Freedom, Security and Justice (AFSJ). Given the sustained interest of governments in the development of this most dynamic policy area in the EU, the investigator expects to generate significant policy-relevant findings that will have an important impact on both academic and governmental debates. The rapid development of the AFSJ in recent years has led to an expansion of the scholarly li",{"id":621,"funder":7,"programme":8,"title":622,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":623},"cordis-marie-skłodowska-curie-actions-award-253837","New Methods to Reconstruct Phylogenetic Networks","Phylogenies are used to describe the history of evolutionarily related biological entities (e.g. genes, individuals, species) and are central in many biological applications, including functional genomics, epidemiology and biodiversity assessment. Many methods for reconstructing and studying phylogenies have been proposed, almost all of which use trees to represent them. Although in many cases this is reasonable, in many others phylogenies should be represented as networks (more precisely direct",{"id":625,"funder":7,"programme":8,"title":626,"piName":10,"institution":627,"country":63,"year":13,"amount":10,"abstract":628},"cordis-marie-skłodowska-curie-actions-award-255024","A Bayesian Model of EEG Source Dynamics and Effective Connectivity","THE UNIVERSITY OF MANCHESTER","This project addresses two methodological challenges pertinent to cognitive brain imaging: Estimating the time varying neural generators of electric\u002Fmagnetic field recordings on the surface of the scalp, and estimating the time varying effective connectivity between these neural generators. Recent theoretical models of perception adopt a generative approach to perception, whereby stimulus processing is controlled by top-down influences that create predictions about forthcoming events. In some ca",{"id":630,"funder":7,"programme":8,"title":631,"piName":10,"institution":212,"country":46,"year":13,"amount":10,"abstract":632},"cordis-marie-skłodowska-curie-actions-award-236122","Active Rejection of Background in Rare Event Searches","ARBRES (Active Rejection of Background in Rare Event Searches) is a proposal for a 24-month Marie Curie fellowship dealing with a key topic in Astroparticle physics: the tagging, the control and the rejection of the radioactive background of surface origin in rare-event searches. The scientific objective of the proposal is to extend significantly the discovery potential of searches for Neutrinoless Double Beta Decay and for WIMPs, hypothetical particles composing Dark Matter. The methods propose",{"id":634,"funder":7,"programme":8,"title":635,"piName":10,"institution":450,"country":90,"year":13,"amount":460,"abstract":636},"cordis-marie-skłodowska-curie-actions-award-254297","Impact of temperature on the vulnerability of Mediterranean seagrasses to phatogens","The increasing rate of global warming predicted for the coming decades will significantly impact coastal ecosystems. Habitats of particular concern in light of the predicted temperature increase are seagrass meadows, which are sensitive indicators of coastal and estuarine health. Another potential threat to seagrasses are pathogens. Pathogens are present in seagrasses around the world and have been responsible for large seagrass losses in the past. In the Mediterranean, the presence of pathogeni",{"id":638,"funder":7,"programme":8,"title":639,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":640},"cordis-marie-skłodowska-curie-actions-award-253678","CO2 Multiphase reActive Transport modElling","CO2 sequestration in geological formations containing saline water has been proposed as solution to reduce gas emission to the atmosphere. Multiphase CO2 storage modelling is a highly challenging problem. CO2-MATE will focus on the processes that govern CO2 flow and transport in saline aquifers. The objective of the project is to contribute to the knowledge of the behaviour of CO2 transport in saline aquifers. In particular CO2-MATE aims (1) to advance in the understanding of the CO2 trapping me",{"id":642,"funder":7,"programme":8,"title":643,"piName":10,"institution":644,"country":40,"year":13,"amount":10,"abstract":645},"cordis-marie-skłodowska-curie-actions-award-250589","Statistical and dynamical analysis of collective behaviour in a three-dimensional motion: Empirical studies and modelling","CONSIGLIO NAZIONALE DELLE RICERCHE","Collective behaviour is ubiquitous in living systems such as flocks of birds, swarms of insects or schools of fishes. It occurs for several reasons which go from predator protection to mating. To better understand those living systems it is therefore important to understand how collective behaviour emerges and its features. For large flocks of birds and swarms of insects little work has been made from the perspective of empirical and statistical analysis towards modelling of different types. Thi",{"id":647,"funder":7,"programme":8,"title":648,"piName":10,"institution":627,"country":63,"year":13,"amount":10,"abstract":649},"cordis-marie-skłodowska-curie-actions-award-235425","Developing business relationships by SMEs in the intercultural environment","In a so-called “new network economy”, SMEs’ success in competitive markets could be achieved by strategies which are designed to allow firms to more easily share and develop resources (e.g. information, processes, and competences) with a wide range of potential stakeholders.  Relationship-based strategies emphasize that to achieve competitive advantage firms should identify, develop and enhance an efficient portfolio of relationships (Zolkiewski and Turnbull, 2002). It is argued that small firms",{"id":651,"funder":7,"programme":8,"title":652,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":653},"cordis-marie-skłodowska-curie-actions-award-237143","Genomics in Agricultural Pest Management","Application of chemical pesticides in agriculture represents one of the major costs of agricultural production and is a key source of environmental pollution, destruction of wildlife and introduction of known carcinogens into the human food chain. The current need for novel methods of pest control coincides with unprecedented advances in genomic analyses of crop plants. The two-spotted spider mite (Tetranychus urticae) is one of the major pests in agriculture. Our group is generating the whole g",{"id":655,"funder":7,"programme":8,"title":656,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":657},"cordis-marie-skłodowska-curie-actions-award-235098","MODULI OF PRINCIPAL G-BUNDLES OVER CURVES","The applicant Christian Pauly plans to stay at the emerging geometry group of the ICMAT (Insituto de Ciencias Matematicas) at the CSIC (Consejo Superior de Investigaciones Cientificas) in Madrid. The proposal describes three research tasks related to principal G-bundles over projective varieties, which have seen recent important progress (strange duality of generalised theta functions, construction of moduli spaces in any characteristic). Special attention is given to the case when the base vari",{"id":659,"funder":7,"programme":8,"title":660,"piName":10,"institution":644,"country":40,"year":13,"amount":10,"abstract":661},"cordis-marie-skłodowska-curie-actions-award-236423","New modular self-assembled homogeneous catalysts for asymmetric synthesis in water","There is a continuous interest to apply homogeneous catalysis to asymmetric synthesis, which is the elective method for drugs production in pharmaceutical industry. Asymmetric catalysis provides the cheapest synthetic route to optically active compounds with minimal number of steps and reduced use of expensive chiral substrates. Replacing conventional methods with those involving asymmetric catalysis is then mandatory to reduce considerably energy\u002Fmaterials costs and the environmental impact of ",{"id":663,"funder":7,"programme":8,"title":664,"piName":10,"institution":644,"country":40,"year":13,"amount":10,"abstract":665},"cordis-marie-skłodowska-curie-actions-award-252906","Optical properties of hybrid organic\u002Finorganic nano-particles for photovoltaic applications: toward a predictive computational approach","Hopes for a new generation of photovoltaic technology (PV) which may overcome the limitations of the present semiconductor-based technology are based on organic materials, due to their light weight and broad absorption spectrum. In this respect, a special role is played by hybrid organic\u002Finorganic nano-particles. Typical hybrid PV (HPVs) are composite films of semiconductor nano-particles (quantum dots) coupled to organic cromophores active in the visible range. Despite the strong efforts to imp",{"id":667,"funder":7,"programme":8,"title":668,"piName":10,"institution":669,"country":670,"year":13,"amount":10,"abstract":671},"cordis-marie-skłodowska-curie-actions-award-235962","Demographic strategies under climate variation: a study on Arctic and Antarctic seabirds","UNIVERSITETET I OSLO","NO","Predicting the impact of future climate changes on populations and biodiversity is of key importance in the connection with the current global warming. It is crucial to understand how organisms are able to cope with climatic variations, especially in polar environments where the effect of climate change is the strongest. Climate changes may have important ecological consequences on the population dynamics on the long-lived organisms. Because they are typically the upper trophic-level predators o",{"id":673,"funder":7,"programme":8,"title":674,"piName":10,"institution":644,"country":40,"year":13,"amount":10,"abstract":675},"cordis-marie-skłodowska-curie-actions-award-237855","Preparation of ionic liquid microcapsule membranes loaded and their application in NMVOCs removal","The intention of our proposal is to demonstrate the feasibility of ionic liquid encapsulated microcapsules as alternatives to conventional separation techniques. Suitable Ionic liquid will be chosen by conventional extraction procedures i.e. solvent extraction. Furthermore, the efficiency (selectivity, perability) and the life of the novel membrane will be compared with the traditional SLM for NMVOCs removal. The novel ionic liquid membrane capsules will be prepared integrating the membrane tech",{"id":677,"funder":7,"programme":8,"title":678,"piName":10,"institution":679,"country":680,"year":13,"amount":10,"abstract":681},"cordis-marie-skłodowska-curie-actions-award-236964","Evolution and function of the Blastocytis mitochondrion-like organelle","UNIVERZITA KARLOVA","CZ","Blastocystis is a unicellular human intestinal parasite, of controversial pathogenicity, that belongs to a diverse eukaryotic phylum called the Stramenopiles. Since Blastocystis is a strict anaerobe, it was thought that it might possess hydrogenosomes, anaerobic ATP-generating organelles related to mitochondria. In contrast to typical hydrogenosomes, Blastocystis has mitochondrion-like organelles (MLOs) with cristae, a transmembrane potential and DNA. Recent work has demonstrated a mitochondrial",{"id":683,"funder":7,"programme":8,"title":684,"piName":10,"institution":534,"country":46,"year":13,"amount":571,"abstract":685},"cordis-marie-skłodowska-curie-actions-award-253873","Basal ganglia and the control of locomotion","The goal of this project is to understand of the mechanisms, at the neuronal network level, by which the basal ganglia control locomotor activity. The rational beyond this objective is twofold. First, altered locomotor activity is a hallmark of motor and psychiatric disorders. Second, the basal ganglia, a group of subcortical nuclei that connects the entire neocortex to locomotor brain centers, are known to control locomotion, but the network mechanisms responsible for this function are still un",{"id":687,"funder":7,"programme":8,"title":688,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":689},"cordis-marie-skłodowska-curie-actions-award-252475","THE ROLE OF RNA SILENCING IN REGULATION OF JASMONATE HORMONE SIGNALLING","RNA silencing and jasmonate (JA) signalling are key pathways that regulate plant development and defence against pests and disease. Evidence indicates that these pathways interact, but the full extent and nature of the interactions are unknown. An accurate understanding of these interactions is crucial to inform crop modification strategies that improve plant defence and growth. RNA silencing targets specific genes using small (s)RNAs. It controls gene expression through processes such as DNA me",{"id":691,"funder":7,"programme":8,"title":692,"piName":10,"institution":450,"country":90,"year":13,"amount":693,"abstract":694},"cordis-marie-skłodowska-curie-actions-award-253917","Cell fusion as regenerative tool for stroke treatment","€152,917","In the last years it has been shown that transplanted adult bone marrow derived stem cells (BMSCs) have the ability to fuse with cells of other types and restore several pathologies such as congenital liver failure and muscular dystrophy. On the nervous system, it was recently reported that bone marrow transplantation (BMT) made 24 hours after the stroke leads to a functional outcome. Cell fusion is one of the underlying mechanisms as it has been shown that it is indirectly implicated in the for",{"id":696,"funder":7,"programme":8,"title":697,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":698},"cordis-marie-skłodowska-curie-actions-award-253129","Study of uniform supported metal complexes and metal clusters at atomic level for catalytic applications","The discovery and optimization of materials with nanometric dimensions (e.g. supported metal clusters) has aroused high interest in catalysis field during the last years. Based on the fact that some elements, such as gold, show unique catalytic properties when properly synthesized in the form of small crystallites, attention has been mainly paid on controlling the physical-chemical characteristics of the supported nanoparticles at atomic scale, taking into account that this matter is crucial for",{"id":700,"funder":7,"programme":8,"title":701,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":702},"cordis-marie-skłodowska-curie-actions-award-235897","Predicting extinction risk in declining species: The role of behavioral and ecological traits","Understanding and predicting the response of animal populations to anthropogenic activity is a major challenge in biodiversity conservation. Species are not equally affected by habitat loss and degradation. However, our current understanding of what makes some species more vulnerable than others is fragmentary, and we have limited tools to use that information for the management and assessment of imperiled populations. Identifying life history, ecological, and behavioral (LEB) traits associated ",{"id":704,"funder":7,"programme":8,"title":705,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":706},"cordis-marie-skłodowska-curie-actions-award-252538","GENOMICS-BASED INVESTIGATIONS INTO OROBANCHE-HOST INTERACTIONS","Parasitic weeds are among the most destructive and difficult-to-control of all weeds and cause important crop losses across Europe and neighbouring regions. The intimate connection establishes by the parasite with the host vascular tissues makes unsuccessful the selective control of the parasite. Our ability to understand the complexities of this parasitic plant-host interaction is limited by a lack of knowledge about the parasite itself, especially with respect to parasite genomics. This propos",{"id":708,"funder":7,"programme":8,"title":709,"piName":10,"institution":450,"country":90,"year":13,"amount":460,"abstract":710},"cordis-marie-skłodowska-curie-actions-award-254773","Solving Aerosol Problems Using Synergistic Strategies","The topic of this research proposal is the source identification of particles in the atmosphere and the physical and chemical transformations occurring in them once emitted. Particles are injected directly into the atmosphere from a number of sources or formed in situ from gaseous precursors compounds. Atmospheric aerosols have several adverse effects on human health and atmospheric visibility, and partly compensate climate forcing by greenhouse gases. These effects depend on particle diameter a",{"id":712,"funder":7,"programme":8,"title":713,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":714},"cordis-marie-skłodowska-curie-actions-award-253635","ROLE OF ASTROCYTES IN NEURONAL NETWORK FUNCTION IN VISUAL CORTEX","The biology of astrocyte–neuron interaction has emerged as a rapidly expanding field and has become one of the most exciting topics in current neuroscience that is changing our understanding of the physiology of the nervous system. In the last few years, evidence obtained by many laboratories has established the existence of neuron-astrocyte communication in culture preparations and brain slices. However, the properties of astrocytes and their physiological role in vivo is largely unknown Numero",{"id":716,"funder":7,"programme":8,"title":717,"piName":10,"institution":450,"country":90,"year":13,"amount":91,"abstract":718},"cordis-marie-skłodowska-curie-actions-award-251913","Molecule formation and quantum correlations in optical lattices","Motivated by recent successes on the creation of ground-state, ultra-cold molecules particularly in experiments in Orsay (France) and Innsbruck (Austria), we want to address several questions on the possibility and future prospects to create a molecular gas trapped in an optical lattice. The use of optical lattices in experiments with cold atoms, pioneered by the group of Immanuel Bloch at Garching (Germany) has led to a new research field, directed to the simulation of condensed matter systems ",{"id":720,"funder":7,"programme":8,"title":721,"piName":10,"institution":722,"country":384,"year":13,"amount":10,"abstract":723},"cordis-marie-skłodowska-curie-actions-award-254326","Coupled-cluster methods for theoretical X-ray spectroscopies","AARHUS UNIVERSITET","To complement the current rapid developments in experimental x-ray spectroscopy, exemplified by a number of new synchrotron installations both in Europe and outside Europe, a strategy for high-accuracy calculations of the relevant physical observables obtained in various modern x-ray spectroscopies is proposed. Specifically, new coupled cluster methods will be developed that allow the theoretical determination of such data with unprecedented accuracy. This will be accomplished by combining the r",{"id":725,"funder":7,"programme":8,"title":726,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":727},"cordis-marie-skłodowska-curie-actions-award-251174","Event Shapes in Soft-Collinear Effective Theory","The aim of the project is to study jet cross sections in electron-positron, and hadron-hadron collisions. Event-shape distributions for electron-positron collisions have been measured extensively with small experimental uncertainties. On the theoretical side event shapes are accessible to high order analytic computations. This information can be used to make precise determinations of the strong coupling and the bottom mass. The theoretical framework is set up to coherently analyse data for diffe",{"id":729,"funder":7,"programme":8,"title":730,"piName":10,"institution":731,"country":577,"year":13,"amount":10,"abstract":732},"cordis-marie-skłodowska-curie-actions-award-255378","Developmental Transcription Factors in Dopamine Neuron Maintenance","KAROLINSKA INSTITUTET","Understanding mechanisms underlying the generation of diverse neuronal subtypes is one of the major challenges in current neuroscience research. Our interest is focused on midbrain dopamine (mdDA) neurons. These cells are essential for the control of multiple brain functions, including movement, emotion and reward, and dysfunction is involved in the pathogenesis of several mental and neurological disorders including Parkinson’s disease (PD). Extensive studies have identified critical regulatory ",{"id":734,"funder":7,"programme":8,"title":735,"piName":10,"institution":722,"country":384,"year":13,"amount":10,"abstract":736},"cordis-marie-skłodowska-curie-actions-award-237561","Mercury biogeochemistry in the high Arctic","The contamination of the Arctic with mercury is of increasing concern and yet our knowledge of mercury biogeochemistry in this environment is rudimentary. We know that mercury reaches the Arctic from sources in lower latitudes by long distance atmospheric transport of elemental mercury and that it is deposited as inorganic mercury following oxidation in the atmosphere, most notably during atmospheric mercury depletion events. We also know that the Arctic food chain is contaminated with the neuro",{"id":738,"funder":7,"programme":8,"title":739,"piName":10,"institution":731,"country":577,"year":13,"amount":10,"abstract":740},"cordis-marie-skłodowska-curie-actions-award-251456","Investigation of influenza immune responses and vaccine efficacy correlates by global expression profiling and immunological analyses in the ferret model of influenza","Pandemic influenza, such as the 2009 H1N1 influenza virus strains that recently emerged in Mexico and in the US, can have serious effects on human health. Development of vaccines that are able to elicit more potent and protective immune responses as well as reducing the impact of future pandemic outbreaks is critical. Successful development of such vaccines is dependent on animal models to test vaccine efficacy and safety. Animal modeling of infectious disease also allows for transcription mappi",{"id":742,"funder":7,"programme":8,"title":743,"piName":10,"institution":731,"country":577,"year":13,"amount":10,"abstract":744},"cordis-marie-skłodowska-curie-actions-award-255003","Molecular mechanisms of pediatric immunodeficiency syndromes affecting natural killer cell cytotoxicity","The pediatric immunodeficiency syndromes familial haemophagocytic lymphohistiocytosis types 3 (FHL3) and 4 (FHL4), and Griscelli syndrome type 2 (GS2) are associated with loss-of-function of Munc13-4, syntaxin 11 (Stx11) and Rab27a, respectively. These proteins are members of families of membrane fusion-regulating proteins, but the precise molecular role of these proteins in granule release is incompletely understood. All of these mutations result in a loss of cytotoxic function by NK cells and ",{"id":746,"funder":7,"programme":8,"title":747,"piName":10,"institution":722,"country":384,"year":13,"amount":10,"abstract":748},"cordis-marie-skłodowska-curie-actions-award-255597","Searching, Matching, Sorting, and Separating in the Labour Market: Costs, Structure and Consequences of Employment Adjustment in Dynamic Frictional Economies","This research seeks to provide answers to three interrelated crucial policy questions on the interdependency of labour and product markets, focusing on the costs, structure and consequences of employment adjustment costs. To this aim, I propose to extend the strong theoretical foundation of dynamic search-matching models, introducing firm specific stochastic productivity shocks, and to structurally estimate these models on Danish exhaustive employer-employee data, with rich information on the fi",{"id":750,"funder":7,"programme":8,"title":751,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":752},"cordis-marie-skłodowska-curie-actions-award-252980","Molecular and ecological approaches to study soil food webs for enhancing biological control of insect pests and monitoring disturbances","Soil is a largely non-renewable resource with high socio-economic and natural value. Soil ecosystems sustain high biodiversity involved in complex food webs that interact with abiotic factors. Understanding these complex interactions could provide a model for monitoring soil disturbances as well as optimizing ecological scenarios to favour biological control. The aim of this post-doctoral research project is to develop and use molecular tools based on quantitative real-time PCR (qPCR) to study f",{"id":754,"funder":7,"programme":8,"title":755,"piName":10,"institution":722,"country":384,"year":13,"amount":756,"abstract":757},"cordis-marie-skłodowska-curie-actions-award-255180","Predicting eutrophication and climate change impacts on shallow lake ecology and biodiversity: disentangling the effects of temperature and nutrients","€205,629","Increased nutrient concentrations in freshwater ecosystems have had profound impacts on their biodiversity, perhaps none more so than in shallow lakes. It may be that impacted systems such as these are particularly vulnerable to climate change. Increasing temperature and eutrophication are not only linked, but their impacts are similar and thus it has proven very difficult to disentangle their effects. It may be that analysis of rate of change may elucidate the effects of climate change and nutr",{"id":759,"funder":7,"programme":8,"title":760,"piName":10,"institution":761,"country":168,"year":13,"amount":10,"abstract":762},"cordis-marie-skłodowska-curie-actions-award-254701","Trust in Social Internetworking Systems","STICHTING VU","Social media applications, such as blogs, multimedia and link sharing sites, question and answering systems, wikis and online forums, are growing at an unprecedented rate and are estimated to generate a significant amount of the contents currently available on the Web. In real cases a user can decide to affiliate to many social networks and to create an account for each of them and the resulting scenario is called social internetworking system (SIS). In the SIS scenario, mechanisms allowing user",{"id":764,"funder":7,"programme":8,"title":765,"piName":10,"institution":450,"country":90,"year":13,"amount":10,"abstract":766},"cordis-marie-skłodowska-curie-actions-award-235365","Diversity patterns across lineages and evolutionary hierarchies in marine unicellular eukaryotes","Microbes dominate the biomass of oceans, having vital roles in the functioning of ecosystems and the biogeochemical cycling. Yet, little is known about the total extent and structuring patterns of their genetic diversity, especially at the species and population levels. Pointing into this research direction, this proposal has two general aims: (a) to go deeper into assessing the extent of picoeukaryotic (2-5µm cell size) diversity in marine environments and (b) to investigate genetic patterns at",{"id":768,"funder":7,"programme":8,"title":769,"piName":10,"institution":770,"country":168,"year":13,"amount":10,"abstract":771},"cordis-marie-skłodowska-curie-actions-award-254069","Virus-like particles: the next step in gene therapy","TECHNISCHE UNIVERSITEIT EINDHOVEN","Virus–like protein particles can be applied as carriers for RNA gene therapy. The release of the RNA, however, is still a major problem. The goal of this proposal is to develop new routes towards the controlled opening of the virus capsid combining the cutting-edge science of bioconjugate chemistry and virology. This project intends to find a suitable carrier among non-infectious virus particles for small interfering RNA (siRNA) to be used for gene therapy. siRNA has the ability to specifically ",{"id":773,"funder":7,"programme":8,"title":774,"piName":10,"institution":770,"country":168,"year":13,"amount":10,"abstract":775},"cordis-marie-skłodowska-curie-actions-award-251200","Hierarchical self-organisation in complex stochastic systems","The proposed research project aims at a rigorous mathematical understanding of the emergence of universal hierarchical structures and of the phenomenon of hierarchical self-organization for paradigmatic stochastic models of complex systems that involve long- and short-range interactions. For this purpose, we shall employ recent breakthroughs in understanding of multiple space-time scale collective behaviour of interacting spatio-temporal random systems. Moreover, we shall employ techniques and o",{"id":777,"funder":7,"programme":8,"title":778,"piName":10,"institution":779,"country":146,"year":13,"amount":780,"abstract":781},"cordis-marie-skłodowska-curie-actions-award-253019","Risk and Equity in Climate Change Problems","UNIVERSITE CATHOLIQUE DE LOUVAIN","€119,950","The issue of climate change is becoming more and more prominent in the public debate. It raises several ethical issues in terms of intergenerational equity and global justice. Standard cost-benefit analysis neglects inequalities, assuming that appropriate redistributions are possible, but such redistributions are unlikely at the large temporal and regional scales involved in climate change issues. Hence it is of particular importance to develop evaluation methods to assess the distributional imp",{"id":783,"funder":7,"programme":8,"title":784,"piName":10,"institution":779,"country":146,"year":13,"amount":10,"abstract":785},"cordis-marie-skłodowska-curie-actions-award-236064","EFFECTS OF LAND COVER CHANGE AND LAND ABANDONMENT ON SEDIMENT YIELD IN SEMIARID MEDITERRANEAN CATCHMENTS USING REMOTE SENSING, GIS AND FIELD TECHNIQUES","The focus of this research project is to quantify the effect of historical land use\u002F-cover change onerosion by combining conventional geomorphic methods, remote sensing and innovative geochemicaltechniques. The Western Mediterranean region is the core region of this project, as it was identified by theUnited Nations as one of the regions mostly affected by desertification in Europe. Its main objective is toprovide quantitative data on the historical evolution of erosion processes in relation to ",{"id":787,"funder":7,"programme":8,"title":788,"piName":10,"institution":789,"country":168,"year":13,"amount":10,"abstract":790},"cordis-marie-skłodowska-curie-actions-award-236281","Dynamic Combinatorial Nanoparticles for Protein Surface Recognition","RIJKSUNIVERSITEIT GRONINGEN","Recent developments in genomics and proteomics have generated an urgent need for new methods of interrogating and targeting biochemical networks. In particular new means of interfering with protein-protein interactions are in high demand and of considerable therapeutic potential. New materials are needed that can recognise and bind to specific protein surfaces. We aim to develop a new approach to the recognition of proteins using individual nanoparticles and dynamic networks of nanoparticles. Th",{"id":792,"funder":7,"programme":8,"title":793,"piName":10,"institution":794,"country":40,"year":13,"amount":10,"abstract":795},"cordis-marie-skłodowska-curie-actions-award-252766","Multifunctional and multifactorial approaches to study physical, chemical and sensory stability of oil-in-water emulsions based on olive oil","ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA","An emulsion consists on two immiscible liquids, usually oil and water, with one of the liquids dispersed as small spherical droplets into the other. Chemical properties of the dispersed phase determine the type of emulsion:Oil-in-Water(O\u002FW) or Water-in-Oil(W\u002FO). Research studies carried out in this field based on the use of different types of lipids, mainly low cost and worldwide distributed ones:soybean, sunflower and colza oils. However, studies about extra virgin olive oil(EVOO), that represe",{"id":797,"funder":7,"programme":8,"title":798,"piName":10,"institution":789,"country":168,"year":13,"amount":10,"abstract":799},"cordis-marie-skłodowska-curie-actions-award-254559","Molecular dynamics simulation of the membrane binding and disruption mechanisms of antimicrobial peptides","Antimicrobial peptides (AMPs) are a promising new class of antibiotics, the mechanism of which usually involves binding to membranes with subsequent disruption. The disruption process is, however, still poorly understood, mostly because it seems to be mediated by states - pore formation or in-depth AMP insertion - that are unordered and very short-lived. My PhD work focused on using and developing biophysical methodologies to study the conditions at which the AMP-mediated disruption is triggered",{"id":801,"funder":7,"programme":8,"title":802,"piName":10,"institution":803,"country":524,"year":13,"amount":804,"abstract":805},"cordis-marie-skłodowska-curie-actions-award-255622","Structural and functional studies on Plasmodium formins","OULUN YLIOPISTO","€174,588","Funding is applied to carry out research on formin-mediated regulation and dynamics of actin-based motility of apicomplexan parasites, such as Plasmodium, the causative agent of malaria. Formins are large multi-domain proteins, which regulate microfilament formation by triggering actin monomer addition from actin-profilin complexes at the barbed end. Formins bear two formin homology (FH) domains. Plasmodium FH2 domains are conserved with higher eukaryotes and are responsible for actin binding, w",{"id":807,"funder":7,"programme":8,"title":808,"piName":10,"institution":789,"country":168,"year":13,"amount":10,"abstract":809},"cordis-marie-skłodowska-curie-actions-award-255129","Intercalated Graphene Carbon Nanotubes for Heterogeneous Catalysis","The objective of this proposal is the synthesis of a new type of carbon-based catalyst for application in heterogeneous catalysis: defect free graphene as well as graphene oxide will be produced and sandwiched with carbon nanotubes through layer-by-layer deposition and intercalation chemistry to yield novel pillared carbon nanotube-graphene structures. Using intercalation chemistry metal atoms and ions will be inserted into their pores to achieve high catalytic turnover and selectivity towards a",{"id":811,"funder":7,"programme":8,"title":812,"piName":10,"institution":779,"country":146,"year":13,"amount":813,"abstract":814},"cordis-marie-skłodowska-curie-actions-award-255604","Dynamics of Soft Metallo-Supramolecular Materials from Entangled Macromolecular Precursors","€159,600","Our project deals with the class of supramolecular systems coined “metallo-supramolecular polymers”, which offer several advantages compared to their covalent counterparts, e.g. a “self-healing” mechanism due to the reversibility of the supramolecular bond. The specific systems based on metallo-terpyridine complexes binding covalent macromolecular precursors, which have been developed at University Catholique de Louvain (UCL) [Guillet et al. (2009)] provide unique tunability and simplicity makin",{"id":816,"funder":7,"programme":8,"title":817,"piName":10,"institution":818,"country":819,"year":13,"amount":10,"abstract":820},"cordis-marie-skłodowska-curie-actions-award-237230","Epistemology and Democracy in Complex Societies (EPIDEMICS)","UNIVERSITY COLLEGE CORK -  NATIONAL UNIVERSITY OF IRELAND, CORK","IE","It is often said that the sciences should be brought into democracy (EC 2000), but conceptual frameworks for making sense of that aspiration are surprisingly underdeveloped. There is a now a wealth of middle-range theoretical and empirical research on new democratic institutional innovations addressing themes such as genetic modification, biosecurity, reproductive technologies and genetic testing, but there has been little synthesis and comparative analysis of these contributions in terms of dem",{"id":822,"funder":7,"programme":8,"title":823,"piName":10,"institution":824,"country":63,"year":13,"amount":10,"abstract":825},"cordis-marie-skłodowska-curie-actions-award-236708","Maternal Communication with embryo","THE UNIVERSITY OF SHEFFIELD","Mechanisms of interactions of embryos with their maternal environment are important biological filters limiting reproductive success, both in livestock and the human. Although several aspects of the embryo-maternal interactome have been studied, there is so far no systematic analysis of this biological module. Increasing our knowledge regarding maternal interaction with embryos will lead to creation of novel molecular markers of fertility that will help to improve the fertility of livestock popu",{"id":827,"funder":7,"programme":8,"title":828,"piName":10,"institution":818,"country":819,"year":13,"amount":10,"abstract":829},"cordis-marie-skłodowska-curie-actions-award-253694","European Orientalisms","The overall aim of this project is a comparative study of German and English Orientalist discourses – Western modes and categories of thinking about the Orient – between 1500 and 1650. The central issue addressed here is whether the German and English experiences of the Orient in this period, more specifically encounters with the Ottoman Empire, differed and, in turn, produced other kinds of Orientalism. This is an important project for a number of reasons: firstly, it will examine the viability",{"id":831,"funder":7,"programme":8,"title":832,"piName":10,"institution":824,"country":63,"year":13,"amount":10,"abstract":833},"cordis-marie-skłodowska-curie-actions-award-254562","Efficient and Effective Evaluation of Information Retrieval Systems","Information Retrieval (IR) is a ubiquitous technology. The range of tasks and information collections IR systems are applied to is ever growing. However, the ability of researchers and developers to build high quality searching systems for new environments is not keeping up with the growth in potential application areas. As a consequence, search system quality is degrading: users of bespoke systems expect a Google-like experience of swift high quality retrieval; instead they commonly get slow su",{"id":835,"funder":7,"programme":8,"title":836,"piName":10,"institution":761,"country":168,"year":13,"amount":10,"abstract":837},"cordis-marie-skłodowska-curie-actions-award-254478","Emission Comb Spectroscopy: Development of novel frequency comb spectroscopy methods based on stimulated Raman scattering","Coherent control of ultrafast lasers results in well-defined frequency combs revolutionizing many aspects in fundamental and applied science. Most recently, frequency comb technology was used to push the performance of Fourier transform spectroscopy to unprecedented levels. Multi-heterodyne spectroscopy is a rapidly growing research field opening new perspectives in terms of sensitivity, spectral resolution and data acquisition time which has been demonstrated in various experiments on absorptio",{"id":839,"funder":7,"programme":8,"title":840,"piName":10,"institution":818,"country":819,"year":13,"amount":10,"abstract":841},"cordis-marie-skłodowska-curie-actions-award-255466","Development of a Novel Vector for Cancer Gene Therapy for Clinical Application","Background: The applicant has generated a body of research work in the field of gene therapy for cancer. Our recent research has shown that oral administration of Bifidobacteria to mice results in translocation from the Gastro-Intestinal Tract (GIT) with subsequent homing to and replication specifically in tumours, providing high-level gene expression confined to tumours. These findings indicate potential for treatment and\u002For detection of cancer via ingestion of non-pathogenic bacteria. We have ",{"id":843,"funder":7,"programme":8,"title":844,"piName":10,"institution":803,"country":524,"year":13,"amount":845,"abstract":846},"cordis-marie-skłodowska-curie-actions-award-254552","Computation of Nuclear Magnetic Relaxation in Paramagnetic Systems","€169,888","The spectral parameters of nuclear magnetic resonance (NMR) provide information on molecular structure and properties. Furthermore, NMR relaxation conveys information on molecular dynamics, rotation, chemical exchange and collisions. Paramagnetic NMR (pNMR) is gaining importance in chemistry, structural biology, magnetic resonance imaging (MRI) and materials science. Open-shell molecules experience the sc. paramagnetic relaxation enhancement (PRE) due to time-dependent interaction of the nuclear",{"id":848,"funder":7,"programme":8,"title":849,"piName":10,"institution":824,"country":63,"year":13,"amount":10,"abstract":850},"cordis-marie-skłodowska-curie-actions-award-252756","The role of animals in late Iron Age and Roman life: cultural identity and the relationship between Italy and Britain","Archaeological evidence has indicated that major cultural changes occurred in Europe between the Late Iron Age and Early Roman periods, although these were neither homogeneous nor universal. The theoretical framework by which to interpret these complex processes has been energetically debated and remains contentious. Animal bones recovered from archaeological habitation sites - mostly the product of meal, kitchen and waste - can reveal far more than merely the diet of past societies. They reflec",{"id":852,"funder":7,"programme":8,"title":853,"piName":10,"institution":854,"country":79,"year":13,"amount":10,"abstract":855},"cordis-marie-skłodowska-curie-actions-award-255588","Deep surveying of CNV impact on Mouse transcriptome complexity and regulation","UNIVERSITE DE LAUSANNE","Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a comprehensive understanding of the phenotypic effect of these structural variations is only beginning to emerge. An extensive map of CNV in wild mice and inbred strains has been established by the host group. These variable regions cover ~11% of their autosomal genome. CNVs are suggested to shape tissue transcriptomes on a global scale and thus represent a substantial source for",{"id":857,"funder":7,"programme":8,"title":858,"piName":10,"institution":854,"country":79,"year":13,"amount":10,"abstract":859},"cordis-marie-skłodowska-curie-actions-award-253729","The role of Casparian Strip formation and degradation in primary and lateral root development","Epithelial polarity is a fundamental feature of multi-cellular life and model systems for animal epithelia have been intensely investigated for decades. One tissue that displays all the hallmarks of an epithelium is the root endodermis. In plants, the endodermis functions as a crucial barrier, separating the outer apoplastic space of the cortical cell layers, often in direct contact with the soil, from the inner apoplastic space of the vascular bundle. To create this barrier, endodermal cells se",{"id":861,"funder":7,"programme":8,"title":862,"piName":10,"institution":854,"country":79,"year":13,"amount":863,"abstract":864},"cordis-marie-skłodowska-curie-actions-award-251712","Environmental heterogeneity and AMF genetic diversity","€243,304","Arbuscular mycorrhizal fungi (AMF) form mutualistic symbiosis with roots of the majority of terrestrial plants. They are ceonocytic, known to harbour genetically different nuclei. However, the dynamic and maintenance of this genetic diversity are unknown. We have recently found two important processes that are likely to play a role in AMF: a) single spores do not necessarily inherit the same genetic material due to unequal segregation of nuclei during spore formation; b) mixing of nuclei between",{"id":866,"funder":7,"programme":8,"title":867,"piName":10,"institution":868,"country":146,"year":13,"amount":869,"abstract":870},"cordis-marie-skłodowska-curie-actions-award-254397","Non-coding RNAs in neurodegeneration","VIB VZW","€214,800","Large non-coding RNAs and microRNAs are important regulators of gene expression that may control both physiological and pathological processes such as neurodegenerative disorders. Given the complexity of neurodegenerative disorders, studying the role of non-coding RNAs would be necessary to understand the molecular mechanisms underlying ageing related neurodegeneration. Of particular interest, microRNAs (miRNAs) seem to participate directly in the regulation of Alzheimer’s Disease (AD) and Parki",{"id":872,"funder":7,"programme":8,"title":873,"piName":10,"institution":868,"country":146,"year":13,"amount":10,"abstract":874},"cordis-marie-skłodowska-curie-actions-award-235827","Regulators of gene networks in Arabidopsis thaliana that confer signalling steady states of high stress adaptability","To compensate for a reduced spatial mobility, plants have evolved a large developmental and adaptive plasticity to cope with environmental fluctuations. Under adverse conditions, such as abiotic stress, this plasticity is of paramount importance for plant survival. It is now clear that adaptation responses in plants are complex at the molecular level and occur through fine tuning and coordination of specific networks of signals and genes. Additionally, increasing evidence points to considerable ",{"id":876,"funder":7,"programme":8,"title":877,"piName":10,"institution":824,"country":63,"year":13,"amount":10,"abstract":878},"cordis-marie-skłodowska-curie-actions-award-236314","ARCHAEOLOGICAL RESEARCH ON ANDALUCIAN POTTERY (8TH-11TH CENTURIES)","This project is intended to study pottery from the Early Medieval Vega of Granada (Spain, 8th to 11th centuries) with archaeometrical and cutting-edge approaches. The aspects researched on will be the changes in technology, distribution, use of resources and organization of pottery production. The techniques used for the study will include thin section petrography and chemical (NAA and SEM) analyses, reproduction of actual shaping techniques and comparisons with local clay samples, known collect",{"id":880,"funder":7,"programme":8,"title":881,"piName":10,"institution":868,"country":146,"year":13,"amount":882,"abstract":883},"cordis-marie-skłodowska-curie-actions-award-252375","Mathematical models for diffusion controlled systems: diffusion on cell membrane, cluster formation and maintenance","€161,600","Assembly of transient and stable signaling platforms in the plasma membrane of cells has been implicated in functions as varied as death and survival, polarity, differentiation, migration, cell-cell communication, virus entry, exocytosis, endocytosis. Naturally, the assembly of signaling microdomains requires the use of most complex molecular mechanisms capable of transducing intrinsic or extrinsic information into the actual making of the domain. Consensus exist that the lateral diffusion and h",{"id":885,"funder":7,"programme":8,"title":886,"piName":10,"institution":887,"country":79,"year":13,"amount":888,"abstract":889},"cordis-marie-skłodowska-curie-actions-award-252330","Genetics of an invasive species and its parasites: the bank vole in Ireland","UNIVERSITAET BERN","€250,642","Invasive species pose major threats to biodiversity, ecosystem integrity, agriculture, fisheries and public health. Greater knowledge of the population genetic aspects of invasions will allow us to discover how invasive species can adapt and thrive in novel environments, despite the founder events and serial bottlenecking associated with expansion into new territory, and will help to generate better management strategies. In this proposal, the researcher will use a state-of-the-art genomics appr",{"id":891,"funder":7,"programme":8,"title":892,"piName":10,"institution":868,"country":146,"year":13,"amount":182,"abstract":893},"cordis-marie-skłodowska-curie-actions-award-254027","Glypican5-supported endocytic control of BMP4 signaling","Increasingly, the glypicans, major membrane proteins that supply heparan sulfate at the surface of cells, emerge as essential for the reception and dissemination of morphogenetic signals. While the best recognized role of endocytosis in signaling is to down-regulate the signal by sending the receptor and\u002For the ligand to degradative compartments such as lysosomes, it has now become clear that endocytosis also contributes to activation of signalling. In this project, we propose to explore the imp",{"id":895,"funder":7,"programme":8,"title":896,"piName":10,"institution":897,"country":63,"year":13,"amount":10,"abstract":898},"cordis-marie-skłodowska-curie-actions-award-255202","Routes to arousal: a simultaneous EEG-FMRI investigation of pharmacological sedation in humans","CARDIFF UNIVERSITY","Functional Magnetic Resonance Imaging studies have progressed from identifying areas of the brain involved in a given task to investigating the temporal correlation or ‘functional connectivity’ between signals from different brain regions. This permits spatial and temporal characterisation of cortical and subcortical functional circuits during the execution of tasks and at rest. Combining information from simultaneous EEG and FMRI measurements affords a still finer physiological fractionation of",{"id":900,"funder":7,"programme":8,"title":901,"piName":10,"institution":902,"country":97,"year":13,"amount":366,"abstract":903},"cordis-marie-skłodowska-curie-actions-award-253952","Structure determination of human and chimpanzee HAR1F RNA by NMR","JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN","The 118-nt long human accelerated region 1 of humans (hHAR1F) possesses the largest genetic drift of all 49 so far identified HARs with an estimated 18 substitutions in comparison to the homologous sequence from the chimpanzee (cHAR1F). In order to understand the unknown function of these non-coding RNAs in the development of human consciousness it is essential to elucidate their secondary and tertiary structures of the HAR RNA with atomic resolution. We will design RNA constructs which will mim",{"id":905,"funder":7,"programme":8,"title":906,"piName":10,"institution":897,"country":63,"year":13,"amount":10,"abstract":907},"cordis-marie-skłodowska-curie-actions-award-254849","Enlightened or just less threatened: Education and anti-immigrant attitudes","This research proposal combines the strengths of sociology and social psychology to investigate the effect of education on anti-immigrant attitudes. Many studies in the last fifty years have found that the higher educated have less negative anti-immigrant attitudes. Anti-immigrant prejudice can have many negative consequences for social integration in communities but also for EU integration. However, the exact nature of the effect of education is unclear, partly as a consequence of the difficult",{"id":909,"funder":7,"programme":8,"title":910,"piName":10,"institution":911,"country":680,"year":13,"amount":10,"abstract":912},"cordis-marie-skłodowska-curie-actions-award-235902","Allosteric effects induced in 14-3-3 targets","Masarykova univerzita","14-3-3 proteins, found in all eukaryotic cells, are known to be important in cell-cycle regulation, apoptosis, and regulation of gene expression. They are also associated with oncogenic and neurodegenerative amyloid diseases. 14-3-3 proteins are active as homo- or heterodimers and bind more than 300 diverse target phosphoproteins, thereby forcing conformational changes or\u002Fand stabilizing active conformations in their target proteins. To date, no crystal structure is known for a 14-3-3 dimer in c",{"id":914,"funder":7,"programme":8,"title":915,"piName":10,"institution":897,"country":63,"year":13,"amount":10,"abstract":916},"cordis-marie-skłodowska-curie-actions-award-254046","Enabling the interoperability of cytometric data – a novel bioinformatics approach for revealing systems level understanding of cell cycle dynamics","The fellowship addresses a growing area of the life sciences interests of the EU community – understanding biological processes at the system level. Availability of high-quality quantitative data constitutes a bottleneck in this area and the fellowship addresses a specific problem. Ongoing efforts to converge genomic and proteomic data aiming to enlarge the systems view through bioinformatics. There is increasing recognition that at the cellular level heterogeneity and dynamic changes are compli",{"id":918,"funder":7,"programme":8,"title":919,"piName":10,"institution":731,"country":577,"year":13,"amount":10,"abstract":920},"cordis-marie-skłodowska-curie-actions-award-252361","Identification of New Genetic Determinants of Plasma Fibrinogen Concentration","The proposed project aims at the identification and characterization of novel genes, genetic variants and pathways implicated in the regulation of plasma fibrinogen concentration, which is an independent risk factor for cardiovascular disease (CVD). Several genome-wide linkage and association studies have identified some interesting regions which may contain candidate genes that are not yet identified. Despite this exciting progress in narrowing down genomic regions that may be linked to plasma ",{"id":922,"funder":7,"programme":8,"title":923,"piName":10,"institution":731,"country":577,"year":13,"amount":10,"abstract":924},"cordis-marie-skłodowska-curie-actions-award-236795","Use of high resolution imaging to elucidate cell migration dynamics within 3D environments","Integrin-mediated cell-matrix adhesion complexes (CMACs) are important modulators of cell adhesion and migration and are key transducers of cell signaling events. In cell migration, correct coordination of CMAC adhesive strength and signaling is pivotal. Cell migration has been extensively studied in 2D cell culture systems, and while studies in more physiological 3D environments are still rudimentary, it is already clear that CMACs behave very differently in 3D environments as compared to 2D. T",{"id":926,"funder":7,"programme":8,"title":927,"piName":10,"institution":928,"country":168,"year":13,"amount":10,"abstract":929},"cordis-marie-skłodowska-curie-actions-award-254736","Dissection of T cell cosignaling and development of vaccination strategies to cytomegalovirus","ACADEMISCH ZIEKENHUIS LEIDEN","Cytomegalovirus (CMV, a β-herpesvirus) infects the majority of the world’s population, establishing a lifelong infection. This infection is largely asymptomatic in immune competent hosts, but causes severe disease in immunocompromised neonates and adults. In healthy persistently infected individuals huge numbers of CMV-specific T cells accumulate over time (i.e. “memory inflation”), a process recently associated with the immune risk profile and immune senescence in the elderly. CMV encodes numer",{"id":931,"funder":7,"programme":8,"title":932,"piName":10,"institution":897,"country":63,"year":13,"amount":933,"abstract":934},"cordis-marie-skłodowska-curie-actions-award-252937","Characterisation, synthesis and functional investigation of epidermal lipoxygenase products in inflammation","€250,351","The skin has many protective functions, acting as a barrier to physical and biological threats from the external environment while regulating water loss and body temperature. Loss of the normal skin function results in inflammation and associated diseases such as psoriasis, alopecia and ichthyosis. The skin is highly-enriched in lipids and fatty acids, which can be converted by lipoxygenase (LOX) enzymes to bioactive mediators, termed eicosanoids. LOXs are a family of non heme iron enzymes of wh",200,{"programme":8,"total":937,"withPiName":938,"firstYear":939,"lastYear":940,"countryCount":941,"perYear":942,"topInstitutions":1018,"topCountries":1094},26094,19,1988,2027,53,[943,945,948,951,954,957,960,963,966,968,971,974,977,980,983,986,989,992,995,998,1001,1004,1007,1010,1013,1016],{"year":939,"count":944},1,{"year":946,"count":947},2003,74,{"year":949,"count":950},2004,586,{"year":952,"count":953},2005,868,{"year":955,"count":956},2006,641,{"year":958,"count":959},2007,553,{"year":961,"count":962},2008,591,{"year":964,"count":965},2009,712,{"year":13,"count":967},787,{"year":969,"count":970},2011,838,{"year":972,"count":973},2012,901,{"year":975,"count":976},2013,1005,{"year":978,"count":979},2014,1009,{"year":981,"count":982},2015,1232,{"year":984,"count":985},2016,1231,{"year":987,"count":988},2017,1209,{"year":990,"count":991},2018,1353,{"year":993,"count":994},2019,1340,{"year":996,"count":997},2020,1314,{"year":999,"count":1000},2021,1688,{"year":1002,"count":1003},2022,1362,{"year":1005,"count":1006},2023,1495,{"year":1008,"count":1009},2024,1522,{"year":1011,"count":1012},2025,1781,{"year":1014,"count":1015},2026,1532,{"year":940,"count":1017},396,[1019,1022,1025,1028,1031,1034,1037,1040,1043,1046,1049,1052,1055,1058,1061,1064,1067,1070,1073,1076,1079,1082,1085,1088,1091],{"name":1020,"count":1021},"Centre National de la Recherche Scientifique CNRS",790,{"name":1023,"count":1024},"The Chancellor Masters and Scholars of the University of Cambridge",636,{"name":1026,"count":1027},"Kobenhavns Universitet",614,{"name":1029,"count":1030},"Chancellor, Masters and Scholars of the University of Oxford",579,{"name":1032,"count":1033},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",484,{"name":1035,"count":1036},"Imperial College of Science Technology and Medicine",428,{"name":1038,"count":1039},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",383,{"name":1041,"count":1042},"University of London",347,{"name":1044,"count":1045},"Katholieke Universiteit Leuven",280,{"name":1047,"count":1048},"The University of Birmingham",247,{"name":1050,"count":1051},"Eidgenoessische Technische Hochschule Zuerich",224,{"name":1053,"count":1054},"Aarhus Universitet",220,{"name":1056,"count":1057},"Universita Ca' Foscari  Venezia",219,{"name":1059,"count":1060},"University of Bristol",213,{"name":1062,"count":1063},"Ecole Polytechnique Federale de Lausanne",182,{"name":1065,"count":1066},"The University of Edinburgh",181,{"name":1068,"count":1069},"Universita Degli Studi di Padova",177,{"name":1071,"count":1072},"Universitat Wien",175,{"name":1074,"count":1075},"University of Leeds",169,{"name":1077,"count":1078},"Universiteit van Amsterdam",159,{"name":1080,"count":1081},"Universitetet I Oslo",156,{"name":1083,"count":1084},"Universiteit Utrecht",152,{"name":1086,"count":1087},"Technische Universiteit Delft",142,{"name":1089,"count":1090},"University of Warwick",141,{"name":1092,"count":1093},"Institut National de la Sante Et de la Recherche Medicale",139,[1095,1097,1099,1101,1103,1105,1107,1109,1111,1113,1115,1117,1119,1121,1123,1125,1127,1129,1131,1134,1137,1140,1143,1146,1149],{"name":63,"count":1096},5982,{"name":46,"count":1098},2854,{"name":90,"count":1100},2844,{"name":97,"count":1102},2362,{"name":40,"count":1104},2058,{"name":168,"count":1106},1624,{"name":384,"count":1108},1173,{"name":79,"count":1110},1075,{"name":146,"count":1112},996,{"name":577,"count":1114},788,{"name":133,"count":1116},634,{"name":819,"count":1118},608,{"name":670,"count":1120},487,{"name":52,"count":1122},482,{"name":524,"count":1124},313,{"name":347,"count":1126},277,{"name":680,"count":1128},256,{"name":139,"count":1130},168,{"name":1132,"count":1133},"TR",147,{"name":1135,"count":1136},"PL",137,{"name":1138,"count":1139},"SI",113,{"name":1141,"count":1142},"CY",99,{"name":1144,"count":1145},"HU",97,{"name":1147,"count":1148},"LU",59,{"name":1150,"count":1151},"LT",56]