[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2012":3,"awarded-stats-msca-postdoctoral-fellowship":895},{"awarded":4,"total":894},[5,15,21,26,33,39,45,52,57,61,67,73,79,85,90,95,99,104,108,112,116,120,124,128,133,137,141,145,150,154,158,162,166,171,175,180,184,188,192,196,200,204,208,212,216,220,224,228,233,237,241,247,253,257,261,265,269,274,278,283,287,291,295,300,305,310,314,318,322,326,331,335,339,343,347,351,355,359,363,367,371,375,379,383,387,391,395,399,404,408,412,416,420,426,430,434,438,442,447,451,455,460,465,469,474,478,484,489,493,497,502,507,513,517,523,528,532,536,540,544,548,552,557,561,565,570,574,578,583,587,591,595,599,603,607,611,615,620,624,628,632,636,640,644,648,652,656,660,664,668,674,680,684,689,693,697,701,705,709,713,718,722,726,730,735,739,743,747,751,755,760,765,770,774,779,783,787,791,796,801,805,809,814,819,823,828,832,838,842,846,851,856,860,865,869,874,878,882,886,890],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":10,"abstract":14},"cordis-marie-skłodowska-curie-actions-award-297925","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","Normannitas: Landscape, Identity and Norman Kingdoms.",null,"UNIVERSITY OF NEWCASTLE UPON TYNE","UK",2012,"The main aim of N-LINK is to compare England and Italy before and after the Norman Conquest, exploring specific European case studies of historic landscape evolution. The research questions are whether, how and why the Normans changed the settlement patterns within their Kingdoms, specifying similarities and differences between both countries by applying and developing new interdisciplinary landscape-focussed methods and tools (especially GIS and HLC).I will investigate the role of the Normans i",{"id":16,"funder":7,"programme":8,"title":17,"piName":10,"institution":18,"country":19,"year":13,"amount":10,"abstract":20},"cordis-marie-skłodowska-curie-actions-award-299202","Saliency-aware High-resolution Video Processing","UNIVERSITE DE RENNES I","FR","The ever-increasing spatial\u002Ftemporal resolution of video such as ultra high definition has raised new challenges on storage, transmission and display for business, home, and mobile video applications, and thus efficient representation, compression, and retargeting of high-resolution (HR) videos become the key issues for effective deployment of these applications. Saliency models can facilitate to address these issues, but in practice, the current state-of-the-art saliency models are insufficient",{"id":22,"funder":7,"programme":8,"title":23,"piName":10,"institution":24,"country":10,"year":13,"amount":10,"abstract":25},"cordis-marie-skłodowska-curie-actions-award-298208","False Poverty: The Cultural, Political and Historical Implications of Literary Accounts of 'Social Passing'","UNIVERSITY COLLEGE LONDON","This project aims to examine the genre of 'social passing' in British writing from the late 1800s onwards. These are accounts written by those faking poverty to report upon the poor. The most important literary examination is in Cunningham’s 1988 British Writers of the Thirties, limited to one decade and but one strand of a larger critical analysis",{"id":27,"funder":7,"programme":8,"title":28,"piName":10,"institution":29,"country":30,"year":13,"amount":31,"abstract":32},"cordis-marie-skłodowska-curie-actions-award-274769","Probing the effect of Time Reversal Symmetry breaking by the application of a local magnetic field in topological insulators","ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN NANOCIENCIAS CIC NANOGUNE","ES","€222,920","Electronic states that could propagate long distances without power dissipation and with spin coherence (i.e. without losing information about their spin state) would be desirable for the design of energy efficient electronic devices and to make reality theoretical proposals of quantum computation devices. Topological insulators are recently discovered materials that may potentially offer these foreseeable properties.  These materials are insulating in bulk, but present metallic edge states that",{"id":34,"funder":7,"programme":8,"title":35,"piName":10,"institution":36,"country":37,"year":13,"amount":10,"abstract":38},"cordis-marie-skłodowska-curie-actions-award-301723","Tailor made lipases for synthetic catalysis in biphasic media: From poly (lactone) applications towards novel sugar esters","FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV","DE","AquaCat aims to design greener chemical processes by combining the use of lipase catalysis to that of aqueous biphasic reaction media with a specific view to the synthesis of poly(lactone) nanoparticles and sugar esters for pharmaceutical, cosmetical and chemical applications. A multidisciplinary approach encompassing physical chemistry and polymer science as well as industrial biotechnology, biocatalysis and enzyme technology will be followed to cover the various relevant scales. AquaCat will t",{"id":40,"funder":7,"programme":8,"title":41,"piName":10,"institution":42,"country":43,"year":13,"amount":10,"abstract":44},"cordis-marie-skłodowska-curie-actions-award-299168","Child directed demonstration across cultures","STICHTING RADBOUD UNIVERSITEIT","NL","Since the seminal work of Grice (1957), speaking is considered an intentional activity in the sense that it serves achieving goals: one of them, specific of humans, is to teach other humans to use new tools and knowledge (Tomasello 1999; Csibra & Gergely 2009). This context of interaction involves often children and this requires a specific type of recipient design mostly studied under the rubric of Child Directed Speech or Motherese. Even so in order for the message being effective, the adult h",{"id":46,"funder":7,"programme":8,"title":47,"piName":10,"institution":48,"country":49,"year":13,"amount":50,"abstract":51},"cordis-marie-skłodowska-curie-actions-award-298664","Molecular electron transport junctions: spectroscopy of vibrational effects and their controlled manipulation","WEIZMANN INSTITUTE OF SCIENCE","IL","€180,342","It is proposed to experimentally study electron transport through molecular junctions and the influence of electron-phonon interaction on the transport, using current-voltage characteristics and inelastic tunneling spectra, while molecular vibrations in the junction are excited with infrared radiation. It has been predicted from theory that the non-equilibrium vibrational distribution will strongly affect the electron transport and that the molecular junction will effectively act as an optical s",{"id":53,"funder":7,"programme":8,"title":54,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":56},"cordis-marie-skłodowska-curie-actions-award-301410","Embodiment of social communication: The affective and sensory bases of second language in early and late bilinguals","UNIVERSITEIT UTRECHT","The proposed research program consists of a series of integrated experiments designed to make a contribution to an improved understanding of communication dynamics in the current reality of multicultural societies that requires participation in two (or more) linguistic communities. Specifically the research investigates the implications of emotion language in primary (L1) and secondary language (L2) in early and late bilinguals. The general argument is that the modalities that ground concepts in",{"id":58,"funder":7,"programme":8,"title":59,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":60},"cordis-marie-skłodowska-curie-actions-award-302549","Neurophysiology of birdsong syntax perception","Like human language, birdsong is hierarchically organized according to particular syntactic constraints (phonological syntax). Interestingly, birds have also been shown to posses impressive capabilities in recognizing syntactic patterns, even artificial ones, which makes them an attractive, but as yet virtually unexplored, model for research into the neural underpinnings of syntax perception. To address this issue at the neurophysiological level, I propose to apply a high-density electrical neur",{"id":62,"funder":7,"programme":8,"title":63,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":66},"cordis-marie-skłodowska-curie-actions-award-300073","Deciphering RNAi machineries required for miRNAs Cell-to-Cell Transfer in Mammals","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","CH","Small RNAs are key post-transcriptional regulators of eukaryotic gene expression. Among the most fascinating aspects of small RNAs is their ability to cross cell boundaries owing to their non-cell-autonomy. Recently, the host laboratory demonstrated that 21-24bp siRNAs could act as mobile silencing signals in Arabidopsis. Interestingly, in C. Elegans, systemic silencing requires SID1, a transmembrane channel through which endogenous double-stranded RNA may be communicated to adjacent cells. Func",{"id":68,"funder":7,"programme":8,"title":69,"piName":10,"institution":70,"country":71,"year":13,"amount":10,"abstract":72},"cordis-marie-skłodowska-curie-actions-award-299777","The role of mitochondrial DNA double-strand break repair in human disease and normal ageing","UMEA UNIVERSITET","SE","Mitochondrial DNA (mtDNA) deletions accumulate in aged post-mitotic tissue and in individuals with neurodegenerative diseases, leading to local energy defects. Understanding the mechanism of mtDNA deletion formation is an essential step in trying to prevent their occurrence.My hypothesis is that mtDNA deletions occur during mtDNA repair via a double strand break (DSB) repair pathway. I will address the different components of this hypothesis by mechanistic studies of cell lines derived from pati",{"id":74,"funder":7,"programme":8,"title":75,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":78},"cordis-marie-skłodowska-curie-actions-award-302297","Biogeochemistry of erosive material deposition in streams: Impact of particulate deposition upon biofilm carbon cycling","UNIVERSITAT WIEN","AT","Inland waterways are an important component of the global carbon cycle, receiving an annual carbon input of ~ 4.8 Pg of carbon per year. Of this approximately 0.6 Pg is buried, entering the lithosphere, whilst 3.3 Pg is recycled through aquatic food webs. These numbers highlight the global importance of streams, rivers lakes and other inland waters but provide little detail regarding the dynamics of organic matter burial and remineralisation. A poorly defined aspect is the relationship between o",{"id":80,"funder":7,"programme":8,"title":81,"piName":10,"institution":82,"country":83,"year":13,"amount":10,"abstract":84},"cordis-marie-skłodowska-curie-actions-award-302009","Hybrid Photonic Metamaterials at the Multiscale","DANMARKS TEKNISKE UNIVERSITET","DK","In recent modern optics, two rapidly developing branches can be identified: (i) photonics, which studies materials structured on a mesoscopic (micrometer or wavelength) scale, and (ii) optics of metamaterials, which are structured on a nanometer (deeply subwavelength) scales. In both these branches, revolutionary degree of control over light propagation and light-matter interaction has been achieved. However, they still remain relatively isolated fields of study.This project is aimed at developi",{"id":86,"funder":7,"programme":8,"title":87,"piName":10,"institution":88,"country":37,"year":13,"amount":10,"abstract":89},"cordis-marie-skłodowska-curie-actions-award-275778","How to involve the European citizenry in European politics? Emotions, media discourse, and mobilisation","FREIE UNIVERSITAET BERLIN","The research project sets out to describe the mechanism that explains how political entrepreneurs created mass mobilisations by engaging European citizens against Haider's FPÖ, against the Bolkestein directive, and against Turkish membership. The lack of citizen participation is often assumed to be the main problem of democracy at the European level. The recent mass mobilisations are puzzling, as not much has changed in the circumstances that were thought to cause the apathy of citizens towards ",{"id":91,"funder":7,"programme":8,"title":92,"piName":10,"institution":93,"country":71,"year":13,"amount":10,"abstract":94},"cordis-marie-skłodowska-curie-actions-award-299441","Asymmetric Halogenation of Olefins Involving Intermolecular Nucleophiles","GOETEBORGS UNIVERSITET","Chirality is fundamental to the vast majority of molecular recognition processes. Therefore, asymmetric synthesis is a cornerstone in the efficient production of modern pharmaceuticals and many other chemicals. Despite ongoing efforts, however, the asymmetric halogenation of olefins using intermolecular nucleophiles has not been achieved with useful enantiomeric excess ratios. The development of a feasible approach has challenged the field to the day. It is highly desirable for the tremendous ex",{"id":96,"funder":7,"programme":8,"title":97,"piName":10,"institution":93,"country":71,"year":13,"amount":10,"abstract":98},"cordis-marie-skłodowska-curie-actions-award-302422","Development of Reporter Tools for an Improved Understanding of Pharmacophore–Protein–Interaction","Halogen bonding is an electron density donation-based weak interaction that has so far almost exclusively been investigated in computational and crystallographic studies. It shows high similaritiesto hydrogen bonding",{"id":100,"funder":7,"programme":8,"title":101,"piName":10,"institution":102,"country":43,"year":13,"amount":10,"abstract":103},"cordis-marie-skłodowska-curie-actions-award-299726","NAnomics in vitro DEvelopmental TOXcology","TECHNISCHE UNIVERSITEIT DELFT","The progress made in improving the development and the production of nanoparticles (NPs) is enormous. Metallic nanoparticles (mNPs) are among the most widely used types of NPs in electronics, foods, containers, pharmaceutical drugs, cosmetics and paints. This trend will lead to an ever-increasing presence of NPs in the environment. This scenario means that humans and the environment will be exposed to more and more nanotechnology-based products whose health risks and environmental impacts of NPs",{"id":105,"funder":7,"programme":8,"title":106,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":107},"cordis-marie-skłodowska-curie-actions-award-300339","Labour Skills from Occupations: Quantifying Human Capital before and during the Industrial Revolution","Most economic growth theorists see human capital input as a key factor in long-term economic development. Little is known, however, about the role of human capital in the historical process of industrialization of Western Europe. Recent empirical attempts to identify human capital in the past face the problem that human capital is difficult to quantify, particularly before public schools become widespread. Existing measures of human capital in preindustrial Europe (notably literacy rates, numera",{"id":109,"funder":7,"programme":8,"title":110,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":111},"cordis-marie-skłodowska-curie-actions-award-299185","Discourse connectives and the mind: a cross-linguistic analysis of processing and acquisition","Discourse connectives like ‘because’ or ‘so’ in English can be used to relate various kinds of propositional contents, such as two events unfolding in the world (The temperature rises because the sun is shining) or a premise and a conclusion in the mind of a speaker (Max is ill because he didn’t come to work). The proposed study will make use of an array of state-of-the-art empirical methods such as eye-tracking, comprehension experiments, constrained elicitation and corpus analysis in order to ",{"id":113,"funder":7,"programme":8,"title":114,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":115},"cordis-marie-skłodowska-curie-actions-award-300083","Evaluating the variability of ecosystem water vapour fluxes and spatiotemporal effects of extreme events","Water vapour fluxes are a key variable in the biosphere-atmosphere exchange of water in terrestrial ecosystems and have strong interactions with the climate system. However, research on the effects of climate change has been largely focused on carbon cycling and therefore, many open questions remain, in particular with respect to the long-term variability of water vapour fluxes and to spatiotemporal patterns in ecosystem responses to extreme events. The project ECOWAX intends to close this knowl",{"id":117,"funder":7,"programme":8,"title":118,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":119},"cordis-marie-skłodowska-curie-actions-award-302102","Modelling and geochemical implications of intra-arc melting: consequences for the composition of the continental crust","Arcs are expected to be the fundamental brick of the Continental Crust (CC). The main problem with this hypothesis is that the bulk CC has an andesitic composition while most arcs are formed by successive inputs of basaltic magmas.If island arcs accretion is indeed the main mechanism of crustal growth, one must explain how arcs can reach an intermediate composition and if these processes are effective in the nature.Intra-arc differentiation takes place in their lower crustal section. Removal of ",{"id":121,"funder":7,"programme":8,"title":122,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":123},"cordis-marie-skłodowska-curie-actions-award-302628","Specificity of Antibiotic Resistance Evolution","Bacterial resistance to antibiotics is a major problem for global public health, but we have an incomplete understanding of the evolutionary and genetic factors that drive the spread of resistance. This proposal is motivated by the concept that some of the key processes in resistance evolution depend on the specificity of the genetic mechanisms involved, which is at present unclear. Specificity here refers to variation of the phenotypic effects of mutations across genotypes (epistasis) or enviro",{"id":125,"funder":7,"programme":8,"title":126,"piName":10,"institution":88,"country":37,"year":13,"amount":10,"abstract":127},"cordis-marie-skłodowska-curie-actions-award-274039","Nanoscale processes in soils: The role of mycorrhizal fungi in aggregation and phosphorus acquisition","Healthy soils containing sufficient mineral nutrition for plants are the basis for our natural ecosystems and food production. Nevertheless, a great proportion of our European soils are subjected to erosion and are infertile. For a better management, we need to better understand the mechanistic processes happening in soils at a nanoscale. Symbiotic arbuscular mycorrhizal fungi (AMF) are important for both soil aggregate built-up via their extensive hyphal network and protein production; and supp",{"id":129,"funder":7,"programme":8,"title":130,"piName":10,"institution":131,"country":19,"year":13,"amount":10,"abstract":132},"cordis-marie-skłodowska-curie-actions-award-300685","Study of attosecond electronic wavepacket dynamics in molecules using High Harmonic Generation","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","Advanced studies of atomic and molecular systems require very precise probes with a few Angström space resolution and a few attosecond time resolution. High Harmonic Generation (HHG) satisfies these two requirements in a single tool: during this process, an intermediate step is the formation of an electronic wave packet in the continuum, whose central wavelength and duration perfectly match the spatial and temporal resolution required. HHG also provides a powerful source of ultrashort coherent X",{"id":134,"funder":7,"programme":8,"title":135,"piName":10,"institution":131,"country":19,"year":13,"amount":10,"abstract":136},"cordis-marie-skłodowska-curie-actions-award-301656","FERROMAGNETIC RESONANCE AT THE ATOMIC SCALE","Magnetoresistance, giant or tunnel, is at the heart of several ‘spintronic’ components, a new branch of electronics based on the spin of the electron with applications in information technology. Because of the never ending drive for miniaturization, spintronics is about to reach the ballistic regime of electronic transport for which spin dependent properties are still not completely understood. Further size reductions can even be achieved in constrictions of atomic sizes obtained by slowly stret",{"id":138,"funder":7,"programme":8,"title":139,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":140},"cordis-marie-skłodowska-curie-actions-award-252881","Discovery of bioactive natural compounds from Traditional Chinese Medicines (TCMs) used against Cardiovascular Disease (CVD)","Major aim of TCM-VASC is the discovery and characterisation of bioactive natural compounds from medicinal plants successfully used for centuries in Traditional Chinese Medicine (TCM) against Cardiovascular Disease (CVD). The discovery of such compounds is of great interest since CVD is the number one cause of mortality and morbidity worldwide. For many TCMs beneficial action on CVD are documented, but their mechanisms of action and the responsible bioactive compounds are largely unknown. The ide",{"id":142,"funder":7,"programme":8,"title":143,"piName":10,"institution":36,"country":37,"year":13,"amount":10,"abstract":144},"cordis-marie-skłodowska-curie-actions-award-275599","Nanocomposite approaches for the deposition of highly active photocatalytic thin films with  plasma technology","Photocatalysis is a potential tool for environmental and effluent water cleaning. Large band gap semiconductors, first of all TiO2, are commonly employed as photocatalysts. However, most of the photocatalytic materials possess band-gaps corresponding to the Ultra-Violet (UV) wavelengths (220-380 nm) and suffer from low efficiencies due to the high degree of recombination between the photogenerated charges carriers. The challenge is to develop a material with optical band gap in the visible wavel",{"id":146,"funder":7,"programme":8,"title":147,"piName":10,"institution":148,"country":37,"year":13,"amount":10,"abstract":149},"cordis-marie-skłodowska-curie-actions-award-300176","NO-dependent protein translocation and S-nitrosylation of nuclear proteins in Arabidopsis thaliana","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","During the last two decades nitric oxide (NO) has emerged as a new chemical messenger in plant biology, which is involved in regulation of many different physiological processes, such as plant defense, transpiration and gas exchange, seed germination, and root development. It is common that many of the biological functions of NO arise as a direct consequence of chemical reactions between proteins and NO or NO oxides. As result of this modification protein activities can be altered, ion channels,",{"id":151,"funder":7,"programme":8,"title":152,"piName":10,"institution":88,"country":37,"year":13,"amount":10,"abstract":153},"cordis-marie-skłodowska-curie-actions-award-300298","A mechanistic analysis of the impact of arbuscular mycorrhiza on ammonia oxidizing community dynamics and nitrification potential rates in N-limited soils","Nitrification represents a key N-cycling process because it impacts biome productivity and interferes with the adaptation strategies of plants. Hence, a lot of research has attempted to disentangle the drivers of ammonia oxidation, the rate limiting step of the process. Amongst them a relatively new identified factor that may affect nitrification appears to be arbuscular mycorrhizal (AM) status of plants. Previous work of the applicant has highlighted that a negative relationship operates for th",{"id":155,"funder":7,"programme":8,"title":156,"piName":10,"institution":42,"country":43,"year":13,"amount":10,"abstract":157},"cordis-marie-skłodowska-curie-actions-award-300519","Studying Morphogenesis by building reaction-diffusion networks in gel bead arrays","Living matter is characterized as operating far out of equilibrium, and most of the cellular non-equilibrium processes are organized in extremely complex networks. A visible demonstration of some networks is morphogenesis, which is the driving force for the formation of patterns in tissue. In this project I aim to systematically study the underlying physical and chemical components of morphogenesis in an artificial system. The main characteristics are coupling of chemical reaction and diffusion ",{"id":159,"funder":7,"programme":8,"title":160,"piName":10,"institution":42,"country":43,"year":13,"amount":10,"abstract":161},"cordis-marie-skłodowska-curie-actions-award-299969","Quantum Gravity and the Early Universe","Quantum Gravity will be studied in the context of early universe cosmology. Specifically, inhomogeneous perturbations, and their evolution, within Loop Quantum Cosmology will be developed so as to allow direct observational testing of the theory.  A phase of the early universe that is dominated by Quantum Gravity may produce effects observable in the detailed structure of the Cosmic Microwave Background or large scale galaxy distributions. In order to understand and quantify such effects the pow",{"id":163,"funder":7,"programme":8,"title":164,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":165},"cordis-marie-skłodowska-curie-actions-award-273872","Regulation of mammary epithelial morphogenesis by microtubule plus-end tracking proteins","The mammary gland functional unit develops as a result of a complex morphogenetic process organizing polarized epithelial cells into a branched network of ducts terminating in acini. Most of human breast cancers originate from transformation of epithelial cells and induce breakdown of this structure. Studies in cells grown in two-dimensional (2D) cultures have shown that microtubules target and regulate actin network and adhesion complexes, which are also known to be essential components of thre",{"id":167,"funder":7,"programme":8,"title":168,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":170},"cordis-marie-skłodowska-curie-actions-award-299045","Relativistic electron beams and radiation sources using high power laser produced plasmas","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","This proposal describes a program of research to be carried out by Prof. Karl Krushelnick of the University of Michigan  during a 12 month visit to ENSTA-LOA in Paris.  He will join the world-leading laser plasma acceleration group of Dr. Victor Malka at LOA.  This research involves the use of the highest power, shortest pulse laser systems available for producing relativistic plasma waves capable of accelerating electron beams to GeV range energies. This is a rapidly growing field of research a",{"id":172,"funder":7,"programme":8,"title":173,"piName":10,"institution":42,"country":43,"year":13,"amount":10,"abstract":174},"cordis-marie-skłodowska-curie-actions-award-299949","Molecular design of biologically inspired soft materials for hard tissue regeneration","The shortcomings of current medical grafting procedures to treat severe bone defects continue to drive the development of alternative therapies. The clinical success of synthetic bone fillers is still disappointingly limited. Although hydrogels have not been classically studied for bone regeneration applications, owing to their inherently low mechanical properties, these highly hydrated soft materials can provide a proper environment to cell adhesion, migration, proliferation and differentiation",{"id":176,"funder":7,"programme":8,"title":177,"piName":10,"institution":178,"country":37,"year":13,"amount":10,"abstract":179},"cordis-marie-skłodowska-curie-actions-award-301729","Enabling Cost-effective Process Simulation for the Composites Industry: Efficient Characterisation of Complex Fibre Preforms","TECHNISCHE UNIVERSITAET MUENCHEN","Composite materials offer significant benefits over traditional engineering materials, combining low mass with increased stiffness and strength, making composite materials a very attractive option for engineers and manufacturers. However, commonly applied manufacturing techniques have been labour and skill intensive. This has significantly increased the usage of a range of processes known as liquid composite moulding (LCM), involving injection of resin into a compressed fibre reinforcement, capa",{"id":181,"funder":7,"programme":8,"title":182,"piName":10,"institution":178,"country":37,"year":13,"amount":10,"abstract":183},"cordis-marie-skłodowska-curie-actions-award-303308","Single-shot X-ray Pulse duration Acquisition (SiXPAc)&Time-Resolved X-ray spectroscopy on molecules (T-ReX)","Three-dimensional (3D) imaging techniques to investigate the spatial composition of crystalline materials and biological specimens have over the last decades been steadily refined to their current nano-scale resolution. However, nearly all of the methods relying on X-ray or electron 3D tomography only deal with static samples and cannot convey simultaneous information about structural changes. One very promising approach in this direction is to make use of ultrabright state-of-the-art X-ray sour",{"id":185,"funder":7,"programme":8,"title":186,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":187},"cordis-marie-skłodowska-curie-actions-award-299939","Not only Whom you Know but also How you Know them Matters:How the Structure of Social Networks affects Racial Prejudice","This project will investigate how structural features of a person’s social network affect the reduction of interethnic prejudice. Examples of such structural features are whether one’s friends know one another and whether friends from one’s own racial group spend time in the same social settings as the friends from other groups. The work builds on recent insights in social psychology on the impact of interethnic friendships on prejudice. Under the supervision of experts at Stanford and Utrecht U",{"id":189,"funder":7,"programme":8,"title":190,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":191},"cordis-marie-skłodowska-curie-actions-award-298284","Exploring the Role of Semivolatile Gas-phase Vapors in Secondary Organic Aerosol Formation","Semivolatile Organic Compounds (SVOCs) play a crucial role in Secondary Organic Aerosol (SOA) formation, a major uncertainty in climate models. SVOCs are products of gas-phase oxidation of Volatile Organic Compounds (VOCs) in the troposphere, but they are very hard to measure in the gas phase. In the following proposed study, a new innovative method will be developed for the quantitative analysis of the burden of semivolatiles. The suitability of the denuders with different coatings will be iden",{"id":193,"funder":7,"programme":8,"title":194,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":195},"cordis-marie-skłodowska-curie-actions-award-300907","Systematic Isolation of Glycosyltransferases in Drosophila melanogaster Using The Toxicity of Fungal Lectins","Glycosyltransferases catalyze the transfer of a sugar from a glycosyl donor to an acceptor substrate and though this action are responsible for the synthesis of the vast array of glycan modifications found in nature. Identifying genes that encode proteins with glycosyltransferase activity and determining the glycan structures generated by a specific glycosyltransferase is challenging. This project exploits the toxicity associated with the glycan-binding function of fungal lectins to systematical",{"id":197,"funder":7,"programme":8,"title":198,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":199},"cordis-marie-skłodowska-curie-actions-award-272962","Sparks of Reason. Urban Culture, Vernacular Rationalism and New Perspectives on the Enlightenment","Current debates on the Enlightenment and its influence on present-day society call for an informed scholarly response. What exactly is the Enlightenment? What are its historical roots and how is it being used in current public debate? This project aims to contribute to such a response by introducing a specific tradition of urban lay philosophy—namely ‘vernacular rationalism’ in the Netherlands—as a new factor in our understanding of the rise and meaning of Enlightenment. As a secondary objective",{"id":201,"funder":7,"programme":8,"title":202,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":203},"cordis-marie-skłodowska-curie-actions-award-298326","Two-Step-Strategy towards an Orthogonal Bio-System","The integration of orthogonality is a crucial research strategy in the rational design of biological systems for novel applications. In order to produce such highly predictable orthogonal systems, we propose to employ cell-free systems of highly engineered composition generated from living cells, which are complex enough to reproduce the major synthetic capabilities of living cells - such as the synthesis of natural and artificial saccharides - but are simplified enough to come close to truly en",{"id":205,"funder":7,"programme":8,"title":206,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":207},"cordis-marie-skłodowska-curie-actions-award-300304","Computational Tools for Cardiac Mechanics","Cardiovascular disease is the leading cause of death and disability in Europe and in the World. Heart failure itself, primarily caused by myocardial infarction, has now reached epidemic proportions. If past clinical therapies have been developed by trial-and-error, new therapies must now be designed through the scientific understanding of the functional and structural changes in diseased hearts. The ultimate aspiration of our research project is to use theoretical modeling, in combination with n",{"id":209,"funder":7,"programme":8,"title":210,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":211},"cordis-marie-skłodowska-curie-actions-award-298559","The structure-based design of a blocker of formation of amyloid fibers of the segment AADTWE in the mutant D38A of the protein transthyretin, which causes familial amyloidosis","Several neurodegenerative and systemic amyloid diseases are putatively caused by the formation of insoluble protein fibrils, which accumulate in human tissues and interfere with normal organ function. The amylome is the set of proteins that are capable of forming amyloid-like fibrils, as consequence of the self-aggregation of some segments.The familial amyloidosis or FAP is a slowly progressive condition characterized by the buildup of abnormal deposits of transthyretin (TTR) in the body's organ",{"id":213,"funder":7,"programme":8,"title":214,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":215},"cordis-marie-skłodowska-curie-actions-award-275303","The role of small RNAs in remyelination","In diseases of the central nervous system (CNS) such as Multiple Sclerosis (MS), myelinating cells are the principal affected cells. Following pathological loss of myelin, remyelination by oligodendrocyte precursors (OPC) occurs but becomes increasingly incomplete and eventually fails in the majority of lesions. Understanding the molecular basis of myelination and remyelination and the regulation of the cells that achieve myelination and remyelination is primordial for both fundamental and clini",{"id":217,"funder":7,"programme":8,"title":218,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":219},"cordis-marie-skłodowska-curie-actions-award-275589","Argonaute-associated factors required for translational repression in plant RNA silencing","MicroRNAs (miRNAs) are key post-transcriptional regulators of eukaryotic gene expression. In plants, most miRNAs associate with AGO1 as part of RNA-induced-silencing-complexes  (RISC) to regulate target mRNAs via perfectly or near-perfecly miRNA-complementarity sites. These sites differ from those found in metazoan miRNA target transcripts, where extensive mis-pairing prevents endonucleolytic cleavage, or ‘slicing’, and favors translational repression as an alternative mode of AGO action. Recent",{"id":221,"funder":7,"programme":8,"title":222,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":223},"cordis-marie-skłodowska-curie-actions-award-271929","Biological Function and Evolution of Phenotypic Noise in N2-fixation on the Single-cell Level","Genetically identical cells that live in a homogeneous environment often show substantial variation in their biological traits; such variation is called phenotypic noise. The level of phenotypic noise has a genetic basis, suggesting that higher levels of phenotypic noise can evolve. In fact, recent theoretical studies suggest that phenotypic noise could be a mechanism for a population of genotypes to respond to uncertain environments in a more efficient way than with conventional signal transduc",{"id":225,"funder":7,"programme":8,"title":226,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":227},"cordis-marie-skłodowska-curie-actions-award-275867","Optomechanical entanglement and teleportation","The control of microscopic physical systems has been demonstrated successfully in numerous experiments, in particular in the field of quantum optics. A current endeavor is to achieve this level of quantum-mechanical control also in the macroscopic domain. Promising systems for this purpose are mechanical oscillators. Quantum-controlled mechanical oscillators would enable fascinating tasks: to study fundamental physics in a completely new parameter regime, to perform quantum information processin",{"id":229,"funder":7,"programme":8,"title":230,"piName":10,"institution":231,"country":12,"year":13,"amount":10,"abstract":232},"cordis-marie-skłodowska-curie-actions-award-303153","The anatomy and dynamics of the cortical processing of naturalistic sounds","UNIVERSITY OF GLASGOW","Sensory systems evolve to allow organisms to know the environment. Psychophysics research of everyday naturalistic sounds shows that audition enables us to get to know the objects in the environment, sound sources, based on the processing of multiple types of sound-related information. This project aims to integrate psychophysics and cognitive neuroscience methods in order to clarify: [Study1] what information drives the cortical processing of everyday naturalistic sounds; [S2] how cortical proc",{"id":234,"funder":7,"programme":8,"title":235,"piName":10,"institution":88,"country":37,"year":13,"amount":10,"abstract":236},"cordis-marie-skłodowska-curie-actions-award-302717","Stimuli-responsive theranostic nanogels based on hyperbranched polyglycerol","Recent advances in medicine and biotechnology have prompted the need to develop nanoengineered delivery systems that can encapsulate a wide variety of novel therapeutics. Moreover, these delivery systems should be “smart”, such that they can deliver their payload at a well-defined time, place, or after a specific stimulus. The ideal drug delivery system should be biodegradable and biocompatible, should benefit from an active and passive targeting, should target only the desired cells, and should",{"id":238,"funder":7,"programme":8,"title":239,"piName":10,"institution":231,"country":12,"year":13,"amount":10,"abstract":240},"cordis-marie-skłodowska-curie-actions-award-301093","Nutrition and reproductive strategies: the influence of dietary antioxidants on telomere dynamics and life history plasticity in birds","EVOTELOX seeks to examine the extent to which environmentally driven variations in early life nutrition influences oxidative status and telomere loss in vivo, and thereby the costs and benefits of different life history trajectories. Despite the promising role of telomere biology in understanding the biology of life spam, currently little is known about factor that affect telomere dynamics in natural systems and whether telomere dynamics during early life may constraint life history traits. The ",{"id":242,"funder":7,"programme":8,"title":243,"piName":10,"institution":244,"country":245,"year":13,"amount":10,"abstract":246},"cordis-marie-skłodowska-curie-actions-award-301974","Human-Information Interaction in 3D Virtual Environments","BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM","HU","The proposed research would allow the Fellow to bring her expertise in Human-Information Interaction (HII) to a unique joint project of the Department of Ergonomics  and Psychology (DEP) at the Budapest University of Technology and Economics (BUTE) in Hungary and the 3DICC Laboratory of the Computer and Automation Research Institute of the Hungarian Academy of Sciences (CARI - HAS) and the BUTE. In the innovative proposed project, the Fellow will study HII in novel 3D virtual environments.Two re",{"id":248,"funder":7,"programme":8,"title":249,"piName":10,"institution":250,"country":251,"year":13,"amount":10,"abstract":252},"cordis-marie-skłodowska-curie-actions-award-300753","Intensity and timing encoding of naturalistic sounds in auditory brainstem neurons of cats and owls","KATHOLIEKE UNIVERSITEIT LEUVEN","BE","Mammals and birds rely heavily on audition to localize prey or escape predator. Many studies demonstrated the high degree of precision the auditory system achieves in encoding sound properties present at both ears, and proposed explanations for  underlying mechanisms. For instance, brainstem neurons are sensitive to certain stimulus properties, such as the interaural time difference present at both ears (ITD), or to the phase of the input sound. In order to assess this neural sensitivity, such e",{"id":254,"funder":7,"programme":8,"title":255,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":256},"cordis-marie-skłodowska-curie-actions-award-299566","Generalized Sampling and Infinite-Dimensional Compressed Sensing","Sampling theory is one of the mainstays of modern signal processing and encompasses mathematical theory from harmonic analysis, functional analysis, operator theory, approximation theory and computational mathematics. It is a field with a vast amount of applications ranging from medical imaging (Magnetic Resonance Imaging and X-ray Computed Tomography) to sound engineering and image processing.The key to a successful mathematical sampling theory for use in applications is to have a model that fi",{"id":258,"funder":7,"programme":8,"title":259,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":260},"cordis-marie-skłodowska-curie-actions-award-299860","ROle of crustacean zooplankton on prokaryotic community composition in the MEsopelagic Ocean","The ROMEO proposal aims at linking aspects of two scientific fields, traditionally separated, zooplankton ecology and microbial oceanography. ROMEO will investigate the influence of zooplankton activity on the prokaryotic community composition and activity in the open North Atlantic. During a four-week expedition in North Atlantic, the dominant crustacean zooplankton will be collected and the community composition of the resident and the transient gut prokaryotes determined during their nocturna",{"id":262,"funder":7,"programme":8,"title":263,"piName":10,"institution":250,"country":251,"year":13,"amount":10,"abstract":264},"cordis-marie-skłodowska-curie-actions-award-273340","Endothelial injury during sepsis: do NET-attached proteases participate in this process?","Every year over 400.000 EU citizens suffer from sepsis and every third of them dies due to the severity of this systemic inflammation. The mortality results from excessive neutrophil activation leading to vasculature malfunctioning and subsequent multiorgan failure.Recently, we (outgoing host) revealed that during bacterial sepsis neutrophils activated by platelets release NETs (neutrophil extracellular traps) that trap and kill bacteria but this occurs at the expense of injury to endothelium (N",{"id":266,"funder":7,"programme":8,"title":267,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":268},"cordis-marie-skłodowska-curie-actions-award-299293","Formation mechanisms of Early Triassic microbialites in the aftermath of the greatest mass extinction (Permian-Triassic-Boundary)","The goal of this project is to understand the causes and modes of microbialite formation in critical periods of Earth history, typified by changing environments using the example of the Permian-Triassic-Boundary mass extinction event, the most fatal ever. In the aftermath of this mass extinction, microbialite-forming microbes became major components of the marine ecosystem, whereas >90% of marine species went extinct. Despite of considerable efforts in recent years, microbialite formation and it",{"id":270,"funder":7,"programme":8,"title":271,"piName":10,"institution":250,"country":251,"year":13,"amount":272,"abstract":273},"cordis-marie-skłodowska-curie-actions-award-298204","NEW THEORETICAL DEVELOPMENTS WITH APPLICATION IN THE AREA OF CYLINDRICAL MICROSTRIP ANTENNAS","€227,800","Progress in practical implementation of conformal antennas has resulted in an ever-rising use of this type of antennas on aircrafts and spacecrafts as well as in flush mounted shipboards and in mobile communication systems. An accurate modeling of these applications requires new theoretical developments. Being much more complicated, the theory of cylindrical microstrip antennas is not developed up to the same level as planar microstrip antenna theory, and advancing this theory would give major a",{"id":275,"funder":7,"programme":8,"title":276,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":277},"cordis-marie-skłodowska-curie-actions-award-299608","Molecular architecture of adaptive diffusion in sibling allopolyploid lineages (Dactylorhiza, Orchidaceae)","Hybridization and genome doubling regularly stimulate plant diversification and speciation. Immediately following a polyploidization event, a genome suffers adjustments in organization and function at the genetic and epigenetic levels. These alterations have the potential to induce novel expression patterns, which together with permanent heterozygosity and gene redundancy, might result in significant phenotypic shifts and elevated evolutionary flexibility. Here we aim to screen genome-wide natur",{"id":279,"funder":7,"programme":8,"title":280,"piName":10,"institution":250,"country":251,"year":13,"amount":281,"abstract":282},"cordis-marie-skłodowska-curie-actions-award-298278","the Physics of Acoustic Materials","€235,000","This project is directed towards material research of acoustic poro-visco elastic materials with the aim to improve physical insight into the acoustic behavior of materials.The project has the following objectives1. Development of fast and robust methods for material characterization2. Development of physical models for poro-visco elastic materials.Material characterization of porous materials is a renowned field of expertise of the host, the Laboratory for Acoustics and Thermal Physics at K.U.L",{"id":284,"funder":7,"programme":8,"title":285,"piName":10,"institution":131,"country":19,"year":13,"amount":10,"abstract":286},"cordis-marie-skłodowska-curie-actions-award-298531","Transport Properties of Ion-Beam Shaped Metallic Nanowires in Vertical Geometry","The study of the transport properties of nanowires grown by bottom-up approaches is a fundamental step toward their technological integration into a real device. Their integration into complex electronic devices by simple and controllable methodologies is the key issue to achieving the evolutionary progress that should permit to improve computers and communication systems such that they offer superior performances and enhanced miniaturization associated with increased computational speed, tera-b",{"id":288,"funder":7,"programme":8,"title":289,"piName":10,"institution":88,"country":37,"year":13,"amount":10,"abstract":290},"cordis-marie-skłodowska-curie-actions-award-299141","Reliable quantum simulators","Building analogue quantum devices that can simulate the behaviour of other quantum systems more efficiently than any classical apparatus is deemed possible and highly desirable. Such advances will give immense boosts to a variety of fields, from nano-devices to quantum chemistry and information technology. A major current roadblock to this end is the fact that special-purpose quantum simulators have no known mechanisms of self-stabilisation or validation protocols",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":294},"cordis-marie-skłodowska-curie-actions-award-301474","Smart nanosystems for advanced cancer therapy","Advances in the preparation of nanotechnology-based materials in medical science pose new challenges in the design of smart nanodevices capable of meeting clinical needs. These systems are called to solve the issues associated to a non-specific delivery of drugs, which lead to the failure of a large number of treatments for oncological diseases.A selective and safe carrier for drug delivery should be actively targeted to malignant cells and display a stimulus-responsive behavior controlled by ex",{"id":296,"funder":7,"programme":8,"title":297,"piName":10,"institution":298,"country":71,"year":13,"amount":10,"abstract":299},"cordis-marie-skłodowska-curie-actions-award-302896","Synergistic modeling of gene-brain couplings with applications in affective neuroscience","Linköping University","Exploiting cross-modal integration for enhanced power and sensitivity, the recently emerged field of imaging genomics is at the frontline of available tools for identifying genes which influence the neurobiology of human behavior and psychiatric illness. Computational approaches are not, however, up to par with the complexity of the disparate data: there is an urgent need for integrative predictive modeling to overcome the interdisciplinary fragmentation between genomics and neuroimaging to harv",{"id":301,"funder":7,"programme":8,"title":302,"piName":10,"institution":169,"country":19,"year":13,"amount":303,"abstract":304},"cordis-marie-skłodowska-curie-actions-award-272351","Nanoscale Photoactivation and Imaging of Synaptic Spine Dynamics","€186,748","Synapses are physical sites of communication that transmit and transform information between neurons in a very rapid and dynamic way. Not surprisingly, malfunctioning synapses are at the root of some of our most prevalent neurological and psychiatric disorders.As synapses are smaller than what diffraction-limited light microscopy can resolve, and densely packed in light-scattering brain tissue, it has been extremely difficult to study their physiology in mechanistic terms. As a result, we still ",{"id":306,"funder":7,"programme":8,"title":307,"piName":10,"institution":93,"country":71,"year":13,"amount":308,"abstract":309},"cordis-marie-skłodowska-curie-actions-award-272348","Targeted conformal radiotherapy of disseminated cancers, using the alpha-particle emitting radionuclides astatine-211, bismuth-213 and actinium-225","€259,065","This fellowship application proposes training in research that investigates the use of alpha-particle emitting radionuclides for targeted therapies of spread cancers. Eradicating disseminated disease using targeted alpha emitters is recognized as being very promising, but only a few research centres world-wide have the necessary infrastructure for advancing the field. Capacity must be held in trained personnel and lab resources. Additionally, availability of radionuclides must be secured. The tr",{"id":311,"funder":7,"programme":8,"title":312,"piName":10,"institution":93,"country":71,"year":13,"amount":10,"abstract":313},"cordis-marie-skłodowska-curie-actions-award-301440","Role of gene silencing pathways in C. elegans nicotine dependence","Drug dependence is a complex behavior induced by psychostimulatory drugs, which affect the central brain reward circuitry by associating themselves with environmental cues. Long-term administration of the drugs results in the development of neural and behavioral plasticity, leading to addiction relapse even after long-term abstinence. Very little is known about the molecular and cellular adaptation that takes place during the processes.There is increasingly growing evidence indicating that small",{"id":315,"funder":7,"programme":8,"title":316,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":317},"cordis-marie-skłodowska-curie-actions-award-298652","In vivo dynamics of nitrosylation and glutathionylation in Chlamydomonas reinhardtii and Saccharomyces cerevisiae","Living cells have evolved a complex network of signaling pathways and adaptative responses which enable them to survive and adapt to diverse environmental challenges. Our increasing understanding of the molecular mechanism of cell signaling has revealed that reactive oxygen species (ROS) and reactive nitrogen species (RNS) act as signaling molecules to transfer extracellular or intracellular information and elicit specific responses. ROS\u002FRNS mainly act through a set of reversible post-translatio",{"id":319,"funder":7,"programme":8,"title":320,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":321},"cordis-marie-skłodowska-curie-actions-award-302215","Synaptic foundations of low level perception","Our visual system has the ability to extract, in a “pop-out” fashion, contrast edges and contours as well as higher order information and statistical regularities from our sensory environment. This primal low-level perceptual analysis is achieved in spite of the continuously updated flow of images received from the environment and the perturbations introduced by the eye movements we generate to scan our surroundings. Underlying this remarkable ability are cortically built-in perceptual grouping ",{"id":323,"funder":7,"programme":8,"title":324,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":325},"cordis-marie-skłodowska-curie-actions-award-298280","Molecular mechanisms of ion channels voltage-dependency","Voltage-gated ion channels are ubiquitously expressed in human tissues where they play diverse physiological functions such as the generation and modulation of the electrical activity in excitable tissues, myocyte contraction, modulation of neurotransmitter and hormone release. Mutations and\u002For altered regulation of these channels are associated to many pathologies such as neuronal, cardiac and muscular diseases. As a result, structural and functional characterization of those channels will cert",{"id":327,"funder":7,"programme":8,"title":328,"piName":10,"institution":250,"country":251,"year":13,"amount":329,"abstract":330},"cordis-marie-skłodowska-curie-actions-award-302034","Corporate Open Disclosure: A Defensive Perspective","€169,800","The research I intend to carry out will shed some systematic light on the strategic motives that lead companies to disclose openly technical knowledge. Put poorely, open disclosure means that companies do not attach any form of property rights to it, like in the case of patents or formal contractual agreements. This behaviour is against the traditional justification of intellectual property rights – especially the patent system – where inventors are granted temporary monopoly over their inventio",{"id":332,"funder":7,"programme":8,"title":333,"piName":10,"institution":102,"country":43,"year":13,"amount":10,"abstract":334},"cordis-marie-skłodowska-curie-actions-award-302158","Quantum Teleportation of Remote Solid-state Spins","Quantum information processing is a key future technology. Algorithms based on quantum information have been proven to offer superior communication security and the ability to solve classes of computational problems that are not accessible to current classical information technology. Quantum entanglement and quantum measurements are two fundamental resources in quantum information. When combined, they enable one of the most dramatic applications of quantum mechanics: the teleportation of a quant",{"id":336,"funder":7,"programme":8,"title":337,"piName":10,"institution":178,"country":37,"year":13,"amount":10,"abstract":338},"cordis-marie-skłodowska-curie-actions-award-298742","Quantum Information Theory with Liouvillians","The project's main goal is composed of a scientific and an academic training component, and it is to be implemented in the Department of Mathematics at the Technical University of Munich in the research group of Prof. Michael Wolf.The first scientific aim is to extend the mathematical framework underlying the ''dissipative paradigm'' of quantum computing, placing special emphasis on continuous-time evolutions that may be controllable to a certain extent and may include non-Markovian elements. Pr",{"id":340,"funder":7,"programme":8,"title":341,"piName":10,"institution":102,"country":43,"year":13,"amount":10,"abstract":342},"cordis-marie-skłodowska-curie-actions-award-302937","Scanning tunneling spectroscopy of topological interfaces for future spintronics","In the last thirty years great progress in solid state physics was mainly driven by the discovery of novel highly unique material systems. Materials such as high tc superconductors, carbon nanotubes, semiconductor nanowires and graphene reshaped our understanding of modern solid state physics. In particular, each of these materials opened a new chapter in the multidisciplinary fields of nanotechnology and nanoscience.In this context, recently discovered topological insulators, a remarkable new m",{"id":344,"funder":7,"programme":8,"title":345,"piName":10,"institution":102,"country":43,"year":13,"amount":10,"abstract":346},"cordis-marie-skłodowska-curie-actions-award-298930","Software Engineering Properties of Functionally Enabled Languages","A new trend in programming languages and system design is the use of constructsderived from the functional language field.  Owning to a variety of inherentcharacteristics, functionally enabled languages are emerging as a competentalternative to object-orientation in environments requiring fast developmentturnover. Despite the apparent increase in their use, the software engineeringproperties, including the alleged advantages, of such languages are largelyunexplored. With the proposed project, I ",{"id":348,"funder":7,"programme":8,"title":349,"piName":10,"institution":178,"country":37,"year":13,"amount":10,"abstract":350},"cordis-marie-skłodowska-curie-actions-award-302157","Nano-Architectures for Ultrafast Optoelectronics","We propose to fabricate nano-patterned electronic circuits to demonstrate the control of the electronic motion by ultrafast photonic tools. Nanowires and nanosheets will play an important role to build the nano-architecture which allows the direct measurement of the photo current induced by intense, near single-cycle light fields with stable well-defined waveforms. Much attention will be focused on gallium nitride nanowires and titanate nanosheets due to their unique optical and electrical prope",{"id":352,"funder":7,"programme":8,"title":353,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":354},"cordis-marie-skłodowska-curie-actions-award-299703","The International Law of Offshore Construction: Cutting Through Fragmented Legal Regimes Towards Better Governance","Offshore constructions rise in numbers and importance. They promise high economic and scientific benefits, but they also increase risks of accidents and environmental damage. The incident of the offshore oil rig “Deepwater Horizon” in the Gulf of Mexico poignantly illustrates the limits of the existing legal framework that is fragmented along the lines of different geographical areas, different sectors of activities, and, notably, different fields of law. No international treaty specifically dea",{"id":356,"funder":7,"programme":8,"title":357,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":358},"cordis-marie-skłodowska-curie-actions-award-272400","Identity development in adolescence: Longitudinal studies on identity transitions, antecedents, and consequences in various gender and ethnic groups","Adolescents need to develop their own identities in order to become responsible adults and citizenships. Furthermore, formation of a firm identity is necessary to promote adolescent mental health and to prevent endorsement of risk and delinquent behaviours.The purpose of this project is to examine identity formation over time and to investigate antecedents and consequences of adolescent identity changes. In order to overcome current shortcomings of the identity research field this project will (",{"id":360,"funder":7,"programme":8,"title":361,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":362},"cordis-marie-skłodowska-curie-actions-award-302640","West African Pentecostal Christianity in Southern Europe. Engendered Spaces, Spiritual Power and Aesthetic Practices","The research proposes to address the social, religious and aesthetic impact of African Pentecostal and Charismatic Christianity in European cities and societies shaped by Catholicism. This approach is applied to the case study of Nigerian and Ghanaian churches in Italy where the Catholic Church plays roles in social and symbolic domination. Using an innovative and creative multidisciplinary approach draw from religious and visual and multimedia studies, the research examines the African Pentecos",{"id":364,"funder":7,"programme":8,"title":365,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":366},"cordis-marie-skłodowska-curie-actions-award-272289","Enhancing motor learning and neural plasticity in robotic gait training","Robotic haptic guidance is a motor-training strategy in which a machine physically interacts with the participant’s limbs during movement training. This strategy is commonly used to reduce performance errors while training dangerous tasks as relearning to walk after a neurologic injury. There is currently little evidence that robotic guidance is beneficial for human motor learning. In fact, a long-standing hypothesis states that physically guiding a movement impairs motor learning. However, rece",{"id":368,"funder":7,"programme":8,"title":369,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":370},"cordis-marie-skłodowska-curie-actions-award-301174","ICEphobicity for severe ICing Environments","Icing on structures represents a severe risk for human safety and has a significant economic impact on operation costs in many different areas such as aeronautics, power systems (e.g. wind turbines and electric power transmission lines), civil construction (e.g. bridges) and oil platforms to name a few. US National Transportation Safety Board (NTSB) estimates that each year there are about 30 icing related accidents in aeronautics in the US alone.Although icing research has a long tradition, the",{"id":372,"funder":7,"programme":8,"title":373,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":374},"cordis-marie-skłodowska-curie-actions-award-301029","Deciphering post-translational control of Argonautes and their effects on small RNA homeostasis (PASRNA)","Argonaute (AGO) proteins are integral components of most small RNA silencing pathways in plants and metazoans. Previous studies in both model systems have demonstrated an inherent link between AGO levels and the steady state expression of global populations of miRNAs, strongly suggesting a layer of homeostatic control. In an effort to understand this phenomenon, we have set out on, a series of experimental approaches to uncover and characterise the mechanisms underlying AGO post-transcriptional ",{"id":376,"funder":7,"programme":8,"title":377,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":378},"cordis-marie-skłodowska-curie-actions-award-298238","The interactions between turbulent penetrative convection and gravity waves: from laboratory experiments to geo- and astrophysical applications","In many geo and astrophysical situations, a turbulent convective fluid layer is separated from a stably stratified one by a relatively sharp interface. Examples include the oceanic upper mixed layer and underlying pycnocline zone, the atmospheric convective layer and overlying stratosphere, the convective and radiative zones in stars. In classical models, stratified zones are often postulated to be motionless. But it has been recognized that gravity waves generated at the convective interface by",{"id":380,"funder":7,"programme":8,"title":381,"piName":10,"institution":250,"country":251,"year":13,"amount":329,"abstract":382},"cordis-marie-skłodowska-curie-actions-award-300096","Crowns of neutrons: reactions and decays to penetrate the halos of Be-14 and He-8","Light, neutron-rich isotopes are some of the most exotic and fascinating nuclei to study with radioactive ion beams. The vicinity of the neutron dripline and the fundamental properties of the nucleon-nucleon interaction give rise, in this isotopes, to a wealth of concurrent phenomena which constitute a considerable experimental and theoretical challenge, such as nuclear halos, nuclear clustering, coupling to the continuum, and shell structure evolution. Because of this rich variety, they constit",{"id":384,"funder":7,"programme":8,"title":385,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":386},"cordis-marie-skłodowska-curie-actions-award-299400","Engineering of an Artificial Capsidic Enzyme for Aqueous Dirhodium Catalysis","Artificial metalloenzymes are expected to bring together the best of the two worlds of homogeneous and enzyme catalysis, combining broad substrate scope with high activity and reaction selectivity under mild conditions. Herein we propose to construct an artificial metalloenzyme based on a dirhodium active site in the capsid scaffold of the protein ferritin. Catalytically competent dirhodium compounds are derived from dirhodium tetraacetate, which possesses fourfold symmetry, with the ligands sym",{"id":388,"funder":7,"programme":8,"title":389,"piName":10,"institution":250,"country":251,"year":13,"amount":329,"abstract":390},"cordis-marie-skłodowska-curie-actions-award-302314","SMOC2 in osteoarthritis","This project will study the role of SMOC2 in the biology and pathology of synovial joints with specific attention towards osteoarthritis (OA), one of the most common chronic diseases. SMOC2 is a novel secreted protein that can interact with bone morphogenetic protein (BMP) and Wingless-like (Wnt) signaling key pathways in joint development, homeostasis, disease and repair. We will use a translational research approach combining in vitro data with mechanistic insights obtained in a well character",{"id":392,"funder":7,"programme":8,"title":393,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":394},"cordis-marie-skłodowska-curie-actions-award-300100","Late Stage Fluorination for Positron Emission Tomography Applications","Positron Emission Tomography (PET) is a powerful non-invasive, real-time imaging technology that can be used to identify and characterize human disease, but is currently limited by deficiencies in chemistry.  While simple molecules can be efficiently prepared, more complex, biomedically interesting molecules often cannot. The short half-life of [18F] (110 min) dictates severe restrictions on the chemical synthesis of PET tracers. Fluoride introduction must occur at a late stage of the synthesis,",{"id":396,"funder":7,"programme":8,"title":397,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":398},"cordis-marie-skłodowska-curie-actions-award-300807","NanoSIMS Enabled Approach to Understand Bacterial and Fungal Cellulose Degraders in Soils","Soils contain the largest pool of carbon on Earth. Cellulose is a major constituent of this carbon since it is a key component of plant structural carbon. Members of the bacteria and fungi are essential for degrading cellulose and thus are essential for cycling carbon. However, the majority of our knowledge on cellulose degradation has been restricted to organisms that we can grow in the laboratory. The reliance on these growth-based methods to understand soil function can be misleading. My prev",{"id":400,"funder":7,"programme":8,"title":401,"piName":10,"institution":402,"country":37,"year":13,"amount":10,"abstract":403},"cordis-marie-skłodowska-curie-actions-award-299263","Super-resolution Fluorescence Microscopy based on Artificial Mesoscopic Structures","JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG","Studies of the dynamical process of biological samples benefits from real-time imaging microscopy which can provide wide-field high resolution with sufficient material contrast. Hence, fluorescence-based microscopy has become one of the essential tools of modern biology. However, fluorescence techniques as other optical tool suffer from a fundamental resolution limit due to the wave nature of light. While resolution is denoted by the ability to discern different objects, much effort has been dev",{"id":405,"funder":7,"programme":8,"title":406,"piName":10,"institution":76,"country":77,"year":13,"amount":10,"abstract":407},"cordis-marie-skłodowska-curie-actions-award-297855","Quantum Optics Tools for Biomedical Imaging","Two-photon fluorescence microscopy has evolved to one of the most powerful tools in biological imaging, especially in the field of neuroscience. It provides improved depth penetration and reduced photo-bleaching of fluorophores and has thus enabled three dimensional structural and functional imaging of biological samples. However, in typical media and with uncorrelated (classical) photons, the two-photon absorption (TPA) process has small interaction strengths and therefore requires large optica",{"id":409,"funder":7,"programme":8,"title":410,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":411},"cordis-marie-skłodowska-curie-actions-award-298513","Into the Icehouse -Ocean temperatures from CLumped Isotopes in Benthic and planktic foraminifera across the Eocene-­Oligocene climate transition","Analysis of the geologic record shows that Earth’s temperature raised suddenly, and plunged precipitously, many times in its history. These abrupt climate transitions presumably occurred because tipping points in the climate system were exceeded. What is the nature of these tipping points? About 34 million years ago one of these abrupt changes occurred, when Earth's climate shifted from a relatively ice-free world to one with glacial conditions and substantial ice sheets on Antarctica. How globa",{"id":413,"funder":7,"programme":8,"title":414,"piName":10,"institution":402,"country":37,"year":13,"amount":10,"abstract":415},"cordis-marie-skłodowska-curie-actions-award-298743","Wound induced electrical signals in Arabidopsis thaliana","Electrical phenomena in plants were first documented in the 1800s, yet progress in this area has been slow. There is evidence that most plants produce electrical signals that travel long distances within the plant. This electrical activity is triggered by biotic and abiotic stimuli, supporting the notion that excitability is a robust biological trait in plants. Major objectives of this project are to characterize waveform parameters (e.g. duration, amplitude) as well as dynamic parameters (e.g. ",{"id":417,"funder":7,"programme":8,"title":418,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":419},"cordis-marie-skłodowska-curie-actions-award-274798","Assessing climate change impacts over large areas of primary forests in southern South America","Many uncertainties still exist about forest dynamic responses to climate change. One major source of uncertainty is how mechanisms at the scale of individuals are linked to ecosystem-level functioning (i.e. carbon exchange, water balance and biodiversity). This project will address this question by developing a modeling framework to analyze forest-climate interactions and ecological mechanisms controlling the response of forests to climate change. The framework will be used to develop a mechanis",{"id":421,"funder":7,"programme":8,"title":422,"piName":10,"institution":423,"country":424,"year":13,"amount":10,"abstract":425},"cordis-marie-skłodowska-curie-actions-award-299089","Active Control of Impact Response of Smart Sandwich Structures","ETHNICON METSOVION POLYTECHNION","EL","Among other structural configurations, sandwich structures consisting of composite faces and foam or honeycomb core exploit their constituent material properties to the maximum by exhibiting highest flexural stiffness to mass ratios. On the other hand, their brittle behavior by high loading rates, as in the case of impact loading, leads to initiation and propagation of damage in the form of cracks and delaminations. The incorporation of multifunctional materials in the sandwich structure could i",{"id":427,"funder":7,"programme":8,"title":428,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":429},"cordis-marie-skłodowska-curie-actions-award-303214","Asymmetric Chlorofunctionalization of Activated carbon-carbon Double bonds","In collaboration with Prof. S. E. Denmark and Prof. E. M. Carreira the researcher will work with two of the world’s leaders in organic chemistry in the complementary areas of methodology development and natural product synthesis, respectively.In the outgoing phase a novel, asymmetric, Lewis base activated, Lewis acid catalysed reaction will be developed to allow for the asymmetric chlorofuntionalization of activated carbon-carbon double bonds. This objective will be achieved through the thorough",{"id":431,"funder":7,"programme":8,"title":432,"piName":10,"institution":55,"country":43,"year":13,"amount":10,"abstract":433},"cordis-marie-skłodowska-curie-actions-award-301662","Induced Resistance in tomato by beneficial microorganisms - Translating Arabidopsis-derived molecular knowledge on defense signaling","Similarly to pathogens, the interaction with beneficial microorganisms (such as growth–promoting rhizobacteria (PGPR) and Trichoderma) can induce in plants a form of immunity and is known as Induced Systemic Resistance (ISR), which renders plants resistant to subsequent attack by a broad spectrum of pathogens. Multidisciplinary strategies and high throughput global methodologies are contributing to understanding of the mechanisms underlying the ISR signaling network. It was demonstrated that div",{"id":435,"funder":7,"programme":8,"title":436,"piName":10,"institution":102,"country":43,"year":13,"amount":10,"abstract":437},"cordis-marie-skłodowska-curie-actions-award-298657","New Urbanism vs Compact City: Investigation of the relationships between urban micro- and macro- scale effects on travel behaviour","Urban sprawl and excessive car use are two critical threats for the sustainability of contemporary cities. Two main planning approaches have so far been proposed to address these phenomena: The “New Urbanism” and the “Compact City”. One of the main criteria was their environmental effectiveness, especially on transport. Thus, a considerable number of studies focused on the relationship between urban form and travel choices. The main difference is that in US the focus was mainly on the relation b",{"id":439,"funder":7,"programme":8,"title":440,"piName":10,"institution":42,"country":43,"year":13,"amount":10,"abstract":441},"cordis-marie-skłodowska-curie-actions-award-300957","The Invisible made Visible:Far-Infrared Spectroscopy in Support of Astrochemistry","The interstellar medium (ISM) is filled with highly diluted matter. Chemical processes in the ISM are largely obscured by interstellar dust, prohibiting a detailed view of the chemical evolution of star forming regions. Far-infrared (terahertz; THz) observations of interstellar gas, ice and dust have the potential to penetrate deeply into molecular clouds and reveal the full history of star and planet formation. Accordingly, Herschel Space Telescope, SOFIA and ALMA, present astronomical flagship",{"id":443,"funder":7,"programme":8,"title":444,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":446},"cordis-marie-skłodowska-curie-actions-award-302724","Dissemination  of proneural brain cancer cells: implication of partial and reversible differentiation into Dcx+ cells","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","Gliomas describe a range of devastating and progressive brain tumours affecting around 25000 people each year in Europe. Glioblastomas represent the most severe and frequent form of gliomas. A major finding in the field of glioblastomas is the recent identification of cancer stem cells within the tumour, holding a high tumorigenic potential. Those stem cell-like cancer cells are multipotent and resistant to radio- and chemotherapy, and are thus very likely to be responsible for the tumour recurr",{"id":448,"funder":7,"programme":8,"title":449,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":450},"cordis-marie-skłodowska-curie-actions-award-301157","Role of Rnd proteins in the regulation of dendrite, spine and synapse formation in the developing hippocampus and their implication in hippocampal-dependent memory","The rapidly growing elderly population and the increasing occurrence of memory disorders make the promotion of “healthy ageing” and the treatment of these disorders a major challenge in our modern societies. However, the development of treatments is hindered mainly because the biological basis of memory is still unclear. For this reason a better understanding of the mechanisms regulating memory processes appears fundamental. Normal development of hippocampal networks is crucial for memory and le",{"id":452,"funder":7,"programme":8,"title":453,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":454},"cordis-marie-skłodowska-curie-actions-award-299993","Fast Mapping: How to acquire new declarative memories independently from the Hippocampus?","Current theories of declarative memory suggest that it is supported by two complementary memory systems: the medial temporal lobe (MTL) which specializes in rapid acquisition of novel associations and the neocortex, which slowly learns through environmental regularities. Gilboa et al. recently reported an extraordinary phenomenon of rapid acquisition of novel arbitrary associations by adults with severe anterograde amnesia due to extensive MTL lesions. These data challenge the accepted view of d",{"id":456,"funder":7,"programme":8,"title":457,"piName":10,"institution":445,"country":19,"year":13,"amount":458,"abstract":459},"cordis-marie-skłodowska-curie-actions-award-273790","Prefrontal and cingulate interactions in cognitive control: reversible inactivation and electrocorticograms","€185,748","An important feature of human cognition is its remarkable flexibility. Cognitive control refers to processes that allow behaviour to vary adaptively depending on current goals. Understanding it is therefore fundamental to knowing how our behaviour can be adapted and flexible. Deficits in cognitive control, and imbalances in related neurotransmitters such as dopamine, are associated with a number of psychological and neurological conditions, including schizophrenia and the cognitive symptoms of P",{"id":461,"funder":7,"programme":8,"title":462,"piName":10,"institution":445,"country":19,"year":13,"amount":463,"abstract":464},"cordis-marie-skłodowska-curie-actions-award-272633","Uncovering the spatial nature of numbers:  An investigation of its origins and neural basis","€261,975","Coding environmental information in spatial terms is a general propensity of our cognitive systems (e.g., the future is ahead of us, the past behind us). One prominent spatial coding is that of number. While it is now well established that adults’ processing of numerical information is accomplished by spontaneously deploying visuo-spatial mental resources, the specific nature, origins, and neural basis of this phenomenon are poorly understood. Accordingly, the present proposal aims to describe t",{"id":466,"funder":7,"programme":8,"title":467,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":468},"cordis-marie-skłodowska-curie-actions-award-298562","Single unusual DNA","Certain nucleic acids sequences can form unusual structures, like triplexes, G-quadruplexes and i-motif. Nowadays, several genetic diseases have proved to be mediated by the formation of non-B DNA structures at certain chromosomal locations. Therefore, it is very important to inversigate these unusual DNA structures, which may well be biologically relevant, at the molecular level. To study the function of such unusual DNA structures in vivo, it is important to understand how they assemble and in",{"id":470,"funder":7,"programme":8,"title":471,"piName":10,"institution":472,"country":71,"year":13,"amount":10,"abstract":473},"cordis-marie-skłodowska-curie-actions-award-300998","PercIGS","UPPSALA UNIVERSITET","To a large extent, the latest CIGS improvement is due to enhancements in the semiconductor material quality. However, as the material quality of the semiconductors improves, other parts of the solar cell are becoming the new bottlenecks to increase the efficiency further towards the theoretical limit for non-concentrated light, which is 30 %.Therefore, this project is focused on an advanced, yet industrially feasible, device structure: The introduction of point contacts and a passivation layer w",{"id":475,"funder":7,"programme":8,"title":476,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":477},"cordis-marie-skłodowska-curie-actions-award-301728","Functional connectivity and the role of hub neurons in epilepsy","Determining the functional structure of neuronal networks has become an increasingly important tool to link functional and anatomical network structure. Recently, the analysis of functional network structure in the developing rodent hippocampus revealed the presence of highly connected, functional “hub neurons” with the ability to greatly influence synchronous network activity.   Additionally, these developmental hub neurons were shown to be early born neurons with an impressive anatomical struc",{"id":479,"funder":7,"programme":8,"title":480,"piName":10,"institution":481,"country":37,"year":13,"amount":482,"abstract":483},"cordis-marie-skłodowska-curie-actions-award-300971","Direct photoelectrochemical generation of solar fuels using dilute nitride III-V compound semiconductor heterostructures on silicon: epitaxy, electrochemistry, and interface characterization","TECHNISCHE UNIVERSITAET ILMENAU","€255,453","The proposed IOF research programme addresses crucial issues of fundamental and technological importance in the field of solar fuel generation. The key success factor is a strong multidisciplinary approach combining top-level electrochemistry, high-end epitaxial III-V device preparation and cutting-edge surface science analytics. At the core of the project are the objectives of:►obtaining record solar to hydrogen efficiencies and lifetimes with III-V\u002FSi tandem devices►enhancing III-V device stab",{"id":485,"funder":7,"programme":8,"title":486,"piName":10,"institution":487,"country":19,"year":13,"amount":10,"abstract":488},"cordis-marie-skłodowska-curie-actions-award-299834","Lyapunov Analysis in the COaSTal Environment","UNIVERSITE D'AIX MARSEILLE","Coastal regions provide a wide range of resources and services, and thus represent an essential environment for human activities. However, coastal areas are rapidly degrading under the pressure of anthropogenic activities and climate change. Hence a correct management of the ecological resources of coastal regions is vital for a sustainable development. A correct management can not be achieved without understanding the mechanisms which regulate and control horizontal transport and cross-shelf ex",{"id":490,"funder":7,"programme":8,"title":491,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":492},"cordis-marie-skłodowska-curie-actions-award-301340","High-intensity focused ultrasound intracardiac ablation with real-time monitoring using shear-wave imaging","Arrhythmias are a major cause of death and disability worldwide and their prevalence is expected to rise with the aging of the population. Recent technological advances have led to the development of new treatments based on radio-frequency (RF) catheter ablation to treat and even cure these conditions. However, challenges in treatment persist. RF ablation is currently performed via direct contact with the endocardium, limiting the depth of tissue injury unless high temperatures are used, which l",{"id":494,"funder":7,"programme":8,"title":495,"piName":10,"institution":487,"country":19,"year":13,"amount":10,"abstract":496},"cordis-marie-skłodowska-curie-actions-award-302208","Dynamic Networks for Lexical Access: Design, Navigation and Interface",".Lexical insertion is a very important process in the production of language, whether verbal or written. It is often metaphorically stated that words are stored in a mental dictionary, called lexicon. The general belief is that the more entries in the lexicon, the better. But having a large number of stored data is not useful if we do not have the right tools to access the information we need. We know also from experience that the lexical choice is not always easy, and sometimes we fail to reach",{"id":498,"funder":7,"programme":8,"title":499,"piName":10,"institution":500,"country":251,"year":13,"amount":10,"abstract":501},"cordis-marie-skłodowska-curie-actions-award-299954","Study of the role of mast cells in the modulation of immune and inflammatory responses associated with eczema: novel genetic approaches from mouse systems and relevance to the human disease","UNIVERSITE DE LIEGE","The overall objective of this grant is to complement Dr. Marichal’s expertise in basic and translational Allergy and Immunology. He will therefore integrate an outstanding laboratory in this area (Pr. Stephen J. Galli’s laboratory) at Stanford University School of Medicine, a world leader in medical education, training and research. Scientifically, Dr. Marichal will acquire cutting-edge knowledge in the detailed mechanistic understanding of allergic disorders, which are increasingly recognized a",{"id":503,"funder":7,"programme":8,"title":504,"piName":10,"institution":505,"country":71,"year":13,"amount":10,"abstract":506},"cordis-marie-skłodowska-curie-actions-award-299490","Förster resonant energy transfer for high efficiency quantum dot solar cells","LULEA TEKNISKA UNIVERSITET","The Project F-LIGHT aims at exploiting in innovative way the Förster resonant energy transfer (FRET) process in excitonic solar cells, by adding proper donor\u002Facceptor (D\u002FA) couples, which lead to broadening of the absorption spectral range and improve the photoconversion efficiency. The D\u002FA couples are composed of commercially available dye molecules and colloidal and non-colloidal quantum dots (QDs).The investigation takes advantage of the outstanding injection properties of commercially availa",{"id":508,"funder":7,"programme":8,"title":509,"piName":10,"institution":510,"country":511,"year":13,"amount":10,"abstract":512},"cordis-marie-skłodowska-curie-actions-award-298555","Formation and roles of the 5',8-cyclo-2'-deoxyguanosine lesion","CONSIGLIO NAZIONALE DELLE RICERCHE","IT","Free radical attack to genetic material leads to damages that are involved in pathologies as well as in aging. Guanine is the preferred oxidation site of DNA, and 8-oxo-dG is used as marker of radical stress, with some drawbacks due to oxidative artefacts during the analysis. The project addresses the chemical biology of 5’,8-cyclo-2’-deoxyguanosine (5’,8-cyclo-dG), a tandem damage produced by free radical insult to the 5’ position of the sugar. The compound has an extra covalent bond between th",{"id":514,"funder":7,"programme":8,"title":515,"piName":10,"institution":487,"country":19,"year":13,"amount":10,"abstract":516},"cordis-marie-skłodowska-curie-actions-award-299753","Alphavirus-specific mechanisms of OAS\u002FRNAse L pathway inhibition, study of non-structural proteins and search for inhibitors.","Emerging and re-emerging Infectious Diseases (EIDs) are defined as infections that have newly appeared in a population or have existed previously but are rapidly increasing in incidence or geographic range. Over the last decades, a number of new emerging diseases, such as HIV\u002FAIDS and SARS, as well as re emerging diseases that increase in incidence or whose geographic range is changing, such as chikungunya or dengue fever, continue to pose a significant threat to populations in Europe and world ",{"id":518,"funder":7,"programme":8,"title":519,"piName":10,"institution":520,"country":521,"year":13,"amount":10,"abstract":522},"cordis-marie-skłodowska-curie-actions-award-273986","Climate-induced phenological change and its consequences for bird populations","UNIVERSITETET I OSLO","NO","Migratory birds have during the last decades advanced their phenology, i.e. the timing of events such as migration and breeding, as a response to climate change. Species unable to adjust their phenology have shown declining populations. Understanding the mechanisms underlying this trend is necessary for predicting long term population dynamical consequences of climate change and taking possible conservational action. The proposed project aims at sorting out associations between phenology and cha",{"id":524,"funder":7,"programme":8,"title":525,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":527},"cordis-marie-skłodowska-curie-actions-award-297728","Graphene Ribbon-based Nanomaterials for Electrochemical Energy Conversion and Storage","THE UNIVERSITY OF MANCHESTER","Graphene ribbon-based nanomaterials were proposed to be used as electrode materials for electrochemical energy conversion and storage devices including fuel cells and supercapacitors. The objectives are to discover the fundamental electrochemical properties of graphene ribbons, to design advanced graphene ribbon-based electrode materials for electrochemical energy conversion and storage devices with significantly improved performance, as well as to demonstrate their structure-property relationsh",{"id":529,"funder":7,"programme":8,"title":530,"piName":10,"institution":520,"country":521,"year":13,"amount":10,"abstract":531},"cordis-marie-skłodowska-curie-actions-award-303139","Women Practitioners of Tibetan Medicine and the Modernisation of Health Care","Since the 1980s there has been a growth in the numbers of female Tibetan medicine practitioners, the so-called amchi, in areas where the Tibetan ‘science of healing’ (sowa rigpa) is practiced: Tibetan areas of China, the Tibetan exile community in India, in Bhutan, Ladakh, Nepal, and in Buryatia and Mongolia. It is currently little understood how the increasing numbers of women amchi have come about, what challenges and opportunities this growth has fostered for themselves and their patients, an",{"id":533,"funder":7,"programme":8,"title":534,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":535},"cordis-marie-skłodowska-curie-actions-award-275063","Swarm Intelligence Simulations as Tools for Molecular Design of Better Medicines","A new generation of medicines, diagnostics and materials are needed to fuel new advances in healthcare and technology. Critical to this are predictive quality software tools to guide molecular design. In the School of Pharmacy at the University of Manchester, our constant aim is to improve the accuracy of the software tools we use in drug design. The aim of this proposal is to develop a more efficient and accurate software tool for prediction of protein-ligand binding affinities. This tool will ",{"id":537,"funder":7,"programme":8,"title":538,"piName":10,"institution":472,"country":71,"year":13,"amount":10,"abstract":539},"cordis-marie-skłodowska-curie-actions-award-299016","New Aspects of the European Influences on the Imagery on the Scandinavian Picture-Runestones Executed in Late Viking Age Art","The more than 2000 Scandinavian picture-runestones form an important part of Late Viking Age art and European art and must be understood in this context. The Mammen, Ringerike and Urnes styles constitute Late Viking Age art throughout the world of the Vikings, i.e. from about 950s to the 1130s AD, with clear European influences on motifs and pictorial structure. This art is an important source to the Christianization of the Vikings.There is a lack of overview and understanding of the imagery of ",{"id":541,"funder":7,"programme":8,"title":542,"piName":10,"institution":487,"country":19,"year":13,"amount":10,"abstract":543},"cordis-marie-skłodowska-curie-actions-award-302010","Isotopes of Zooplankton to measure climate and human impacts on pelagic food webs","In all pelagic marine food-webs, zooplankton are the critical link between the phytoplankton primary producers and higher trophic levels, including fish. On-going changes observed for zooplankton communities in the Mediterranean and other oceans around the world therefore have serious implications for food-web productivity, and their continued provision of ecosystem services (e.g., food security). Current gaps in our knowledge of how the zooplankton component of the food-web functions, limit our",{"id":545,"funder":7,"programme":8,"title":546,"piName":10,"institution":520,"country":521,"year":13,"amount":10,"abstract":547},"cordis-marie-skłodowska-curie-actions-award-302329","Reconstructing the imprint of ecology on the genetic phylogeography of the Plague in Central Asia and China","Yersinia pestis, the causative agent of plague, is a flea-borne disease that caused at least three devastating pandemics in the last two millenia[Stenseth08]. Plague is endemic in wildlife rodents, and the ecological and epidemiological dynamics of the rodent-plague system are the underlying cause of outbreaks in human populations. However, our current understanding of this system is insufficient to mitigate the risk. In this project the researcher will uniquely combine the disciplines of theore",{"id":549,"funder":7,"programme":8,"title":550,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":551},"cordis-marie-skłodowska-curie-actions-award-301125","Composition and Management of Polymorphic Services","To achieve flexible service provision software services can be endowed with self-* capabilities, such as self-adaptation and self-organisation, and service composition and management can take place autonomically. Such services are termed “polymorphic” since their functionality and structure vary dynamically. The view in the proposed project is that the autonomic behaviour of polymorphic services can be effectively supported by an agent architecture realising bio-inspired self-organisation and de",{"id":553,"funder":7,"programme":8,"title":554,"piName":10,"institution":445,"country":19,"year":13,"amount":555,"abstract":556},"cordis-marie-skłodowska-curie-actions-award-273143","Epigenetic regulation of the sex chromosomes and male infertility","€185,248","Human infertility affects ~15% of couples, each partner being equally likely to be affected. Sperm differentiation anomalies such as sperm absence, malformation or reduced motility, are commonly found in infertile men but their cause remains unknown in ~75% of the cases. In mammals, sperm differentiation requires a high proportion of genes located on the sex chromosomes and a tight epigenetic control of their expression. Alterations of the epigenetic marks associated with these spermiogenic gene",{"id":558,"funder":7,"programme":8,"title":559,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":560},"cordis-marie-skłodowska-curie-actions-award-300582","A novel bioinformatics’ platform to identify key proteasic pathways involved in kidney diseases","The aim of this project is to develop a new bioinformatics’ platform that will for the first time allow the identification of the key proteasic pathways involved in the development of kidney disease in an automatic and systematic way. Proteases generate peptides through cleavage of specific sites, present on given protein substrates. Interestingly, recent clinical studies have led to the identification of diagnostic and prognostic peptide biomarkers of a variety of nephropathies. The platform wi",{"id":562,"funder":7,"programme":8,"title":563,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":564},"cordis-marie-skłodowska-curie-actions-award-300402","developing hybrid organic-inorganic rotaxanes for quantum information processing","The proposed project is based on recent results reported (Nature 2009, 458, 314; J. Am. Chem. Soc., 2010, 132, 15435) by the Winpenny group where they showed that heterometallic rings could be grown around organic threads, producing a new form of rotaxanes with both inorganic and organic components. [3]rotaxanes could be made as prototypes for two qubit gates for quantum computers.Quantum computers will use quantum binary digits, or qubits (the quantum analogue of the classical bit). Their compl",{"id":566,"funder":7,"programme":8,"title":567,"piName":10,"institution":487,"country":19,"year":13,"amount":568,"abstract":569},"cordis-marie-skłodowska-curie-actions-award-272204","The Automatic Generation of Lexical Databases Analogous to WordNet","€258,475","WordNet is a lexical database of English where words are grouped into sets of synonyms (synsets), each expressing a distinct concept. Synsets are interlinked by means of conceptual-semantic and lexical relations. WordNet has turned out to be an indispensable resource in the processing of natural language, and based on its model similar lexical databases were created for many other languages.However, constructing such databases takes many years of work and is very costly. On the other hand, metho",{"id":571,"funder":7,"programme":8,"title":572,"piName":10,"institution":445,"country":19,"year":13,"amount":10,"abstract":573},"cordis-marie-skłodowska-curie-actions-award-298839","Role of microRNAs in host responses to Crohn's disease-associated adherent-invasive Escherichia coli","Recent studies have shown dysregulation of microRNAs (miRNAs) in the mucosa of Crohn’s disease (CD) patients, suggesting a role for miRNAs as contributors to inflammatory bowel disease (IBD) susceptibility. The scientists from the host institution previously showed that ileal lesions in CD patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC), which are able to invade and to replicate within intestinal epithelial cells, and that functional autophagy is required to restra",{"id":575,"funder":7,"programme":8,"title":576,"piName":10,"institution":500,"country":251,"year":13,"amount":10,"abstract":577},"cordis-marie-skłodowska-curie-actions-award-301519","Identification of regulator variants in Rheumatoid Arthritis and Crohn’s Disease","Rheumatoid Arthritis (RA) and Crohn’s disease (CD) are two common chronic autoimmune and complex diseases where individual susceptibility is determined by a combination of environmental and genetic factors. Almost all of the ~100 risk alleles discovered through recent genetic studies fall in non-coding region and have an elusive function. We hypothesize that risk alleles impact gene regulation by altering regulatory elements (e.g. enhancers) controlling the expression levels of genes within the ",{"id":579,"funder":7,"programme":8,"title":580,"piName":10,"institution":581,"country":30,"year":13,"amount":10,"abstract":582},"cordis-marie-skłodowska-curie-actions-award-300854","Ancient DNA and climatic change: new perspectives from insular environments","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","One of the most exciting issues in modern biology is the use of genetic sequences to examine how modern patterns of biodiversity were generated. While most studies use DNA sequences from living species to investigate the factors promoting diversification and extinction, continuous improvements in ancient DNA (aDNA) techniques have greatly opened up the study of DNA sequences from fossils. aDNA has proved an important new tool for the analysis of past demography, migration and diversity and has r",{"id":584,"funder":7,"programme":8,"title":585,"piName":10,"institution":526,"country":12,"year":13,"amount":10,"abstract":586},"cordis-marie-skłodowska-curie-actions-award-300062","Intelligent Decision Making Systems in European Business and Economics","In this proposal we want to develop new decision making models and analyze its usefulness in European business and economic problems. For doing so, we use a wide range of techniques commonly used in the area of soft computing. Especially, we focus on the use of the ordered weighted average (OWA). The OWA operator is an aggregation operator that provides a parameterized family of aggregation operators between the minimum and the maximum. Thus, in decision making it can be used as a tool for measu",{"id":588,"funder":7,"programme":8,"title":589,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":590},"cordis-marie-skłodowska-curie-actions-award-299731","Quantum Hall states in ultracold atomic gases","The fractional quantum Hall effect is one of the most intriguing quantum effects and the topic of much study in condensed matter physics. In the field of ultracold atomic gases, it has been a long endeavor to reach an experimental regime in which the associated strong correlation phenomena can appear. In this project, we want to explore two separate roads towards this regime. In a bulk system, we want to reduce the atom number to mesoscopic values in order to reach to required small fraction of ",{"id":592,"funder":7,"programme":8,"title":593,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":594},"cordis-marie-skłodowska-curie-actions-award-298741","Microscopic Plasma Sources: Novel Diagnostics and Circuit Integration","It is proposed that Lawrence J. Overzet (LJO), Professor and Assoc. Depart. Chair of Electrical Engineering at The Univ. of Texas at Dallas, move to work with R. Dussart, P. Lefaucheux and their team at CNRS-GREMI \u002F Polytech Orleans for 12 months.  The work will focus on micro-plasma source diagnostics and development. In particular, the team will research novel and quantitative diagnostics of micro plasma sources (MPSs) and Micro-Cathode Sustained Discharges (MCSDs). The objective will be to de",{"id":596,"funder":7,"programme":8,"title":597,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":598},"cordis-marie-skłodowska-curie-actions-award-301166","Temporal Reasoning with Data for Verification","The development of formal methods for the verification of computer systems is recognizedas a grand challenge by many research institutions. A successful approach for the verification ofsystems consists in modelling the system to be verified by a mathematical structure andin expressing behavioral properties in a logical formalism. The assumption that programs arefinite-state is usually too restrictive and model-checking techniques for infinite-state systemshave flourished these last 20 years. Our",{"id":600,"funder":7,"programme":8,"title":601,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":602},"cordis-marie-skłodowska-curie-actions-award-298076","Deciphering mycobacterial subversion of early steps of adaptive immunity in vivo: A new approach to solve an old problem","Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) and currently one third of the world’s population is latently infected with Mtb, in spite of the existence of a vaccine. This scenario is in part due to Mtb’s ability to adapt to current treatments, e.g. development of multi-resistance to antibiotics. However we also lack a proper understanding of the immunological mechanisms subverted by Mtb to establish a chronic infection and the reasons for the failure of the current v",{"id":604,"funder":7,"programme":8,"title":605,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":606},"cordis-marie-skłodowska-curie-actions-award-298449","Interactions between polarons in polarized Fermi gases","In this application, we propose to study the physics of the polaronic gas. In a spin imbalanced Fermi gas, that is with a larger number of spin up particles than with spin down, the usual Cooper pairing scenario no longer applies, and this raises the question of the possible phases of the system. It was recently proposed by C. Lobo et. al. [PRL 97, 200403 (2006)], that in the strong imbalanced regime the minority atoms dressed by the Fermi sea of the majority atoms form a weakly interacting gas ",{"id":608,"funder":7,"programme":8,"title":609,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":610},"cordis-marie-skłodowska-curie-actions-award-301583","Roles of genetics and environmental variability in animal population resilience: empirical testing in a changing world","Current climate change is threatening biodiversity more than ever due to the speed at which climate variables are shifting. Coupled with omnipresent land-use change, they are the two factors considered as the most important threats to terrestrial biodiversity. Very little is known of the respective joint contributions of climate change and habitat heterogeneity on the genetic make-up of natural vertebrate populations, which ultimately act on gene flow, genetic structure, and evolutionary adaptat",{"id":612,"funder":7,"programme":8,"title":613,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":614},"cordis-marie-skłodowska-curie-actions-award-300150","Cell biology of rice aquaporins","Although they are exposed to ever changing and sometimes challenging environmental conditions, higher plants can achieve remarkable metabolic and growth performances. For this, they have to precisely maintain their water status and failure to do so can dramatically impact their growth and ultimately their survival. The control of water flow in the soil-plant-atmosphere continuum and the fine-tuning of water transport within the plant body represent important mechanisms in these respects. Because",{"id":616,"funder":7,"programme":8,"title":617,"piName":10,"institution":169,"country":19,"year":13,"amount":618,"abstract":619},"cordis-marie-skłodowska-curie-actions-award-273551","HEADLINES. A historical study of the iconic transverse section of the head and the process of building a scientific consensus about the mind (1400-1550)","€178,048","‘Headlines’ aims to study the visual cross-section of the head - a specific technique of projecting the inside as well as the outside of our head in a special way of ordering space as a show-box. This picture was developed in the early fourteenth century, was consolidated in scholarly work in the fifteenth and lasted until the seventeenth century, carrying Aristotelian concepts into the modern epoch. This iconic cross-section has been of great epistemological value in the process of disclosing a",{"id":621,"funder":7,"programme":8,"title":622,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":623},"cordis-marie-skłodowska-curie-actions-award-299292","Direct Imaging of Budding and Fusion of Lipid Droplets Mediated by Proteins in Emulsion Droplets Based on Microfluidics - Dynamics of Proteins Interactions, Assembly and Metabolism Energy","Lipid droplets (LDs) were believed many years ago to be mere passive reservoirs of lipids, which role was limited to supply lipids to cell membranes when needed and to avoid the accumulation of fat in adipocytes leading obesity. Since this last decade a newly focus on LDs has led to understand their dynamic organelles behavior and their implication in many diseases proliferation in cells. Indeed, the virus or proteins linked to them are located on LDs and therefore the understanding of the bioge",{"id":625,"funder":7,"programme":8,"title":626,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":627},"cordis-marie-skłodowska-curie-actions-award-299384","GEOSOX: Geochronology of secondary oxide minerals in bedrock and fluid flow and deformation histories","Secondary Fe- and Mn-oxide minerals are common in crustal rocks, where they form by fluid flow long after initial formation of their host rocks. This fluid flow represents episodes of deformation, magmatic events, hydrocarbon migration, or topographic and climatic changes that drive groundwater flow. Understanding these processes constrains deformation, resources, hydrology, and landscape evolution.This proposal aims to determine deposition ages of Fe- and Mn-oxides from two geologic environment",{"id":629,"funder":7,"programme":8,"title":630,"piName":10,"institution":169,"country":19,"year":13,"amount":458,"abstract":631},"cordis-marie-skłodowska-curie-actions-award-273567","Dynamic super-resolution mapping of neurotransmitter release events and synaptic glutamate receptors","Proper functioning of the brain requires points of rapid communication between nerve cells. This is achieved at specialized junctions called chemical synapses, which function by the vesicular release of neurotransmitter onto a post-synaptic apposition decorated with neurotransmitter-gated ion channels. Fast chemical synapses release glutamate to activate AMPA-type glutamate receptor ion channels, which excite the post-synaptic neuron. Since these receptors desensitize rapidly, their dynamic exch",{"id":633,"funder":7,"programme":8,"title":634,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":635},"cordis-marie-skłodowska-curie-actions-award-301466","Functional roles of long noncoding RNAs in drought stress responses of Arabidopsis","In the coming decade declining water availability will exert increasing pressure on crop productivity worldwide. One of the solutions is to breed crop plants with enhanced drought tolerance.  Whilst plant breeders are continuing to make progress in this direction, elucidation of the molecular basis of drought stress will help not only traditional breeding efforts but also formulate new transgenic strategies to produce plants with enhanced adaptability under conditions of water limitation.The tra",{"id":637,"funder":7,"programme":8,"title":638,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":639},"cordis-marie-skłodowska-curie-actions-award-298415","Interaction of Cooper Pairs and Massless Dirac Fermions in Suspended Superconductor-Graphene Devices","Superconductivity occurs in a metal when the temperature is low enough to favour the appearance of a new ground state comprised of time-reversed pairs of electrons. These composite particles, called Cooper pairs, form a condensate giving rise to the extraordinary phenomena characteristic of superconductivity, including zero electrical resistivity and perfect diamagnetism. Graphene is a two dimensional crystal of carbon atoms which despite being non-superconducting exhibits another type of emerge",{"id":641,"funder":7,"programme":8,"title":642,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":643},"cordis-marie-skłodowska-curie-actions-award-298355","Paleomagnetism of extraterrestrial materials: a clue to early magnetic fields in the solar system and asteroids differentiation","The study of the remanent magnetization (paleomagnetism) of extraterrestrial materials gives clues as to the history of the primitive solar system and its evolution. Indeed, paleomagnetic studies of meteorites provide a unique window into understanding early solar magnetic fields generated externally from planetesimal bodies (by the young sun during its putative T Tauri phase, or within the protoplanetary nebula), as well as magnetic fields generated within the planetesimals through convection o",{"id":645,"funder":7,"programme":8,"title":646,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":647},"cordis-marie-skłodowska-curie-actions-award-302309","High precision reactor neutrino programm at APC","This proposal has been designed for Dr Novella to become involved in fundamental neutrino oscillation research with the Double Chooz (DC) experiment, led by Dr de Kerret and Dr Cabrera (at the AstroParticule et Cosmologie laboratory). DC is the most competitive EU-based neutrino oscillations experiment, which leads the world on the measurement of the PMNS mixing matrix parameter theta13. DC should improve the current limit by x7 from the best limit to date set by the CHOOZ experiment. The main c",{"id":649,"funder":7,"programme":8,"title":650,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":651},"cordis-marie-skłodowska-curie-actions-award-301196","Developing an evolutionary framework for understanding species co-existence: importance of intraspecific genetic variaiton for community ecology","The main goal of this IEF proposal is to allow the fellow to develop an entirely new set of theoretical skills complementing her extensive experimental expertise in the area of plant ecology and evolution. Theoretical training will be achieved by developing evolutionary biology models for targeted questions in the area of community ecology. These models will be conceptually novel by incorporating rigorous population genetic theory into long-standing community ecology questions. Models will be de",{"id":653,"funder":7,"programme":8,"title":654,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":655},"cordis-marie-skłodowska-curie-actions-award-301120","Sheep and goat management in Cyprus from the Neolithic to the Bronze Age: an archaeozoological, isotopic and ethnographic approach","The main objective of the proposed project is an archaeozoological study of the role that sheep and goat played from the Neolithic to the Bronze Age in Cyprus. Sheep and goat assumed a pivotal role in many aspects of life in Cyprus, such as the economy, natural environment, way of life, etc. In order to fully understand this role, it is necessary to study the diachronic relationship between these two species and humans. To better evaluate the Cypriot data and contextualise their interpretation, ",{"id":657,"funder":7,"programme":8,"title":658,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":659},"cordis-marie-skłodowska-curie-actions-award-298786","Dynamics of Loop Quantum Gravity","Loop Quantum Gravity (LQG) is an approach toward the background-independent quantization of the gravitational field. It is an exciting research area with many recent breakthroughs. LQG predicts the discreteness of the quantum geometry at the Planck scale, thus provides us new understandings of the spacetime structure in the fundamental physics.The dynamical properties of LQG plays a crucial role in the framework of LQG. However there are many key issues in the dynamics of LQG, which have not bee",{"id":661,"funder":7,"programme":8,"title":662,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":663},"cordis-marie-skłodowska-curie-actions-award-302103","Tau Toolkit for opening the New Physics Window at LHC and possible spin off effects","The applicant, from Seoul National University proposes to develop novel tools and research strategies for exploring the physics beyond the Standard Model (BSM), at the LHC at CERN, by taking part to the CMS multipurpose experiment from 2012 to 2014. This exciting period will witness a new major step in the LHC program and BSM exploration, with important Physics results from the 5 -10 fb-1 recorded data and the LHC reaching highest luminosity and preparing for doubling energy. This project takes ",{"id":665,"funder":7,"programme":8,"title":666,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":667},"cordis-marie-skłodowska-curie-actions-award-302807","The Role of Intention in Language Processing","The ability to use language is one of the defining properties of human cognition. On the one hand, the purely linguistic aspects involved in the comprehension and production of language are a uniquely human faculty. On the other hand, the use of language involves complex, higher-order functioning such as intention, essential to mental life. Indeed, a reader and speaker can choose which written information to consciously process and which words to say, respectively, as well as use these skills fo",{"id":669,"funder":7,"programme":8,"title":670,"piName":10,"institution":671,"country":672,"year":13,"amount":10,"abstract":673},"cordis-marie-skłodowska-curie-actions-award-302349","Molecular and morphological systematics of the Polyporales, a highly diverse, poorly documented clade of wood-decaying fungi with biotechnological potential","HELSINGIN YLIOPISTO","FI","The research focus of this project is systematics of the Polyporales, a diverse clade of the basidiomycetes. The Polyporales play a dominant role in timber decay in nature, and their ability to enzymatically decay wood is under intense research for biotechnological uses. Yet no phylogeny or modern classification exists for the Polyporales. This project will produce both.University of Helsinki has a long tradition in morphology-based research of the Polyporales. Dr. Otto Miettinen, the fellow, ha",{"id":675,"funder":7,"programme":8,"title":676,"piName":10,"institution":677,"country":678,"year":13,"amount":10,"abstract":679},"cordis-marie-skłodowska-curie-actions-award-302868","Linking global species richness and beta diversity to individual species distributions at multiple phylogenentic and spatial scales","UNIVERZITA KARLOVA","CZ","Recently, unprecedented amounts of information on the World’s biodiversity have been assembled and striking patterns in its distribution have been described, such as the latitudinal gradient of species richness or the relationship between the richness and climate. Major challenges are to establish linkages between the various biodiversity patterns, to understand the mechanisms generating these patterns, and to make the results of macroecology useful for conservation biology and policy. This proj",{"id":681,"funder":7,"programme":8,"title":682,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":683},"cordis-marie-skłodowska-curie-actions-award-302819","cerebellar molecular layer Interneuron network imaging in awake animal","Molecular layer interneurons form an interconnected network in the cerebellar cortex that controls the activity of Purkinje cells. Even though much is known about the properties of these interneurons in isolated preparations, their activity pattern in vivo remains largely unknown. The present project proposes to investigate the functional status of the interneurons in awake, head-restrained mice, by performing two photon calcium imaging of the cerebellum with genetically-encoded calcium indicato",{"id":685,"funder":7,"programme":8,"title":686,"piName":10,"institution":687,"country":30,"year":13,"amount":10,"abstract":688},"cordis-marie-skłodowska-curie-actions-award-302038","Testing the portability of techniques to handle dissimilar source and target languages in MT","UNIVERSIDAD DEL PAIS VASCO\u002F EUSKAL HERRIKO UNIBERTSITATEA","The aim of the ENEUS project is to develop an English-Basque machine translation system which responds to two main objectives: (1) it contributes to the MT research field by testing the portability of techniques to handle dissimilar source and target languages",{"id":690,"funder":7,"programme":8,"title":691,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":692},"cordis-marie-skłodowska-curie-actions-award-300185","Real-Time Studies of Biological NanoMachines in Action by NMR","Protein Quality Control is an essential and evolutionary-conserved process that is present in all kingdoms of life. In cells, both newly synthesized and pre-existing proteins are constantly prone to misfolding and aggregation. The accumulation of damaged proteins can perturb cellular homeostasis and provoke aging, pathological states and cell death. Accordingly, cells have developed an enzymatic machinery – molecular chaperones – that rescues misfolded proteins by catalyzing their conversion bac",{"id":694,"funder":7,"programme":8,"title":695,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":696},"cordis-marie-skłodowska-curie-actions-award-298910","Creation, evaluation and characterization of the ideal bioprobe for the cancer antigen Tn by improved selection of mutant lectins from phage display libraries","Major changes in carbohydrate expression occur during the onset and progression of cancer. These alterations in glycosylation may result in both the loss of normal carbohydrate antigens (e.g. ABO blood group antigens) and\u002For high expression of carbohydrate structures that normally have low or restricted expression in healthy adults.The Tn antigen is expressed in most carcinomas, during embryogenesis, on pathogenic parasites, and on HIV, yet its expression is rare in normal adult tissue, creating",{"id":698,"funder":7,"programme":8,"title":699,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":700},"cordis-marie-skłodowska-curie-actions-award-275289","FUNCTIONAL GENOMICS STUDIES IN MARINE PRIMARY PRODUCTIVITY: ENVIRONMENTAL AND POLUTION EFFECTS ON PHYTOPLANKTON","One of the most serious challenges for humankind this century will be to understand how climate change (past, present and future) influences life in the oceans. It is known that marine phytoplankton carry out almost half of the global net photosynthesis of the planet. Therefore it will be essential to determine how climate change alters microbial metabolism. However, the integration of cell biology and genomics into oceanographic research is not sufficiently developed, even though biological (an",{"id":702,"funder":7,"programme":8,"title":703,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":704},"cordis-marie-skłodowska-curie-actions-award-299973","Nonuniversal statistics in MHD turbulence","The nature of interactions between different scales in magnetohydrodynamic (MHD) turbulence is paramount for the understanding of flows occurring in fusion plasmas, the geospace, the heliosphere, the interstellar medium, and their influence for example on cosmic ray propagation, the solar-terrestrial interactions. The different degrees of nonuniversality observed at present studies, and the existence of nonlocal processes in MHD turbulent flows, call for a discussion about the validity of the lo",{"id":706,"funder":7,"programme":8,"title":707,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":708},"cordis-marie-skłodowska-curie-actions-award-303293","Dynamic and Plasticity of Spatial Perception and Attention Neural Processes","Spatial attention is vital for interacting with the surrounding environment. Recent studies in cognitive neuroscience suggest that the fronto-parietal regions may exert a top-down attentional influence on early sensory processing areas. However the dynamics and the role of these cortical interactions remain poorly understood. Furthermore, spatial perception was shown to be modulated by subtle knowledge about our previous, on-going and up-coming action. The current project aims to provide direct ",{"id":710,"funder":7,"programme":8,"title":711,"piName":10,"institution":671,"country":672,"year":13,"amount":10,"abstract":712},"cordis-marie-skłodowska-curie-actions-award-300186","Solanum in Europe: phylogeny and genetic diversity","Solanum is a genus of nearly 1 400 species and only a small portion of them are cultivated. This genus is important from an agricultural perspective as well as from an evolutionary standpoint, consisting of valuable crops like eggplant, tomato, and especially potato all important in European agriculture. Very little is known about the biology of European native species despite the fact that they offer unexploited genetic resources right here in Europe. The most important European native species ",{"id":714,"funder":7,"programme":8,"title":715,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":717},"cordis-marie-skłodowska-curie-actions-award-303031","Eurosceptic Populist Party Organization and Representation: A Comparative Study","EUROPEAN UNIVERSITY INSTITUTE","This proposal can be summed up under the following two headings 'Project' and 'Training'. While separate here for clarity, the conduct and success of each is essentially intertwined with - and dependent on - the other:(1) PROJECT: The project analyzes party organization and representation in six Eurosceptic populist parties: the Northern League (Italy), Sinn Féin (Ireland), the Swiss People's Party (Switzerland), Front National (France), the Danish People's Party (Denmark) and the Socialist Part",{"id":719,"funder":7,"programme":8,"title":720,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":721},"cordis-marie-skłodowska-curie-actions-award-298376","Transformations of violence during the decline of insurgencies","This research project examines the transformation of violence during the decline of violent insurgencies. It starts from the observation that forms of violence and violent actors change and are re-shaped in various ways over the course of violent conflict, in particular during phases of decline. These processes often contribute to ending insurgent campaigns by weakening, isolating, or fragmenting insurgent movements, but at the same time entail a proliferation of armed groups and can result in t",{"id":723,"funder":7,"programme":8,"title":724,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":725},"cordis-marie-skłodowska-curie-actions-award-298333","Cooperating in Complex Environments: Cross-cultural Trade, Commercial Networks and Notarial Culture in Alexandria (Egypt) : 1360-1450","In the late Middle Ages a constellation of groups shared the commercial spaces of Mediterranean cities. These groups were either formally defined (as the trading nations of Venice, Genoa, Catalonia, Ancona, Naples, Florence, Montpellier, etc.), or were based on ethnic and religious affiliation (as Copts, Cretan Jews, Greek Orthodox, Jacobites, or Mudéjar Muslims). In either case, to different degrees, these groups cooperated with each other by working together in commonly shared networks. By mon",{"id":727,"funder":7,"programme":8,"title":728,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":729},"cordis-marie-skłodowska-curie-actions-award-300614","Urban Regeneration Governance for Smart, Sustainable and Inclusive Cities: An International Comparison of France and the UK","This proposal aims to support the career development of an experienced researcher, through an interdisciplinary research project that addresses a crucial policy issue of the 21st century, that of urban governance.  The research will take an innovative approach to exploring governance of urban regeneration projects in two member states, France and the UK, being examples of countries with contrasting institutional, economic, social and cultural traditions in relation to government and governance.U",{"id":731,"funder":7,"programme":8,"title":732,"piName":10,"institution":716,"country":511,"year":13,"amount":733,"abstract":734},"cordis-marie-skłodowska-curie-actions-award-272107","The Invisible Politics of Religion: Catholicism, Third Sector and Territory in Southern Europe","€243,575","This research project aims at contributing to the debate over religion and politics in the EU by considering the role played by Catholicism in shaping civil society mobilizations in Southern European regions. The underlying theoretical issues of this project do refer to the classical debates about a) the weberian perspective on the elective affinities between religious ethics, economic and politics; b) the role of culture and social capital in the regional economic development; c) the neo-instit",{"id":736,"funder":7,"programme":8,"title":737,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":738},"cordis-marie-skłodowska-curie-actions-award-301873","Transnational networking, knowledge circulation and technological change in early modern East Central Europe. The case of Hutterite artisans (c.1560-1720)","My research is focusing on knowledge circulation and technological change in early modernEurope. Drawing on the sociology of ‘sociotechnical’ change, it investigates how various patterns of transnational networking facilitated technological innovation. Using the case of dissemination of faience in East Central Europe in the context of the Anabaptist migration (c.1560-1720), I will explore such questions as how a network becomes productive and how transnational non-economic ties become sources of",{"id":740,"funder":7,"programme":8,"title":741,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":742},"cordis-marie-skłodowska-curie-actions-award-300146","“War of Waves”. European Radio Propaganda in the Arab World: the Experience of Radio Bari (1934-43)","This project deals with the radio propaganda that Italy, Great Britain, France and Germany carried out in the Arab world between the mid-1930s and the early 1940s. In particular, it focuses on Radio Bari (1934-43), the first radio station to broadcast in Arabic with the purpose of courting the Arabs and challenging the French and British colonial power.This topic has attracted scholarly interest but as of yet has not been addressed thoroughly. My research is the first one to tackle this issue in",{"id":744,"funder":7,"programme":8,"title":745,"piName":10,"institution":169,"country":19,"year":13,"amount":10,"abstract":746},"cordis-marie-skłodowska-curie-actions-award-297917","Combining holographic optogenetics and STED microscopy for studying synaptic plasticity in Alzheimer ’s disease","New perspectives are opening in neuroscience: the era of electricity is transitioning into the era of light. Super-resolution microscopy was elected “Method of the year 2008” and optogenetics “Method of the year 2010” by the Journal Nature Methods.HOLOSTED is a biophysics project using these modern optical methods to study the effects of Alzheimer’s disease (AD) on synaptic plasticity. It has two general objectives: First, improving optical methods, including STED (STimulated Emission Depletion)",{"id":748,"funder":7,"programme":8,"title":749,"piName":10,"institution":581,"country":30,"year":13,"amount":10,"abstract":750},"cordis-marie-skłodowska-curie-actions-award-274379","Chemical evaluation of drinking water disinfection byproducts","Disinfection byproducts (DBPs) are generated when disinfectants such as chlorine, ozone, chloramine, or chlorine dioxide, react with natural organic matter and\u002For bromide\u002Fiodide present in source waters, and they may pose health risks. Despite intense research carried out in this field, more than 50% of the total organic halogens formed during water disinfection still remain unidentified. Additionally, iodinated DBPs have been found not only in naturally iodide containing waters disinfected, but",{"id":752,"funder":7,"programme":8,"title":753,"piName":10,"institution":716,"country":511,"year":13,"amount":10,"abstract":754},"cordis-marie-skłodowska-curie-actions-award-298752","Female migrants from developed countries in Southern Europe: A study of integration","Women-migrants in Europe often face the ‘double disadvantage’ [as women and as foreigners] in the two main, mutually reinforcing aspects of their migration careers [the socio-political disadvantage and the labour market disadvantage] (Boswell et a. 2004",{"id":756,"funder":7,"programme":8,"title":757,"piName":10,"institution":500,"country":251,"year":13,"amount":758,"abstract":759},"cordis-marie-skłodowska-curie-actions-award-272247","Defining the functions of Elongator in adult brain neurogenesis","€170,500","The olfactory bulb (OB) is one of the few structures in the adult forebrain in which there is a continuous supply of newborn neurons. Neuronal precursors are generated in the subventricular zone (SVZ) and follow an intricate migration path before reaching their final position in the OB.Familial dysautonomia is a neurodegenerative disorder that result from the impairment of Elongator activity. Elongator is a six unit complex assembled by its scaffold protein Elp1. The host laboratory has recently",{"id":761,"funder":7,"programme":8,"title":762,"piName":10,"institution":169,"country":19,"year":13,"amount":763,"abstract":764},"cordis-marie-skłodowska-curie-actions-award-275952","Thermodynamic investigation of magnetic field induced quantum phase transitions","€194,064","The central objective of the present proposal is to improve our understanding of quantum phase transitions and related emergence of novel quantum phases, such as unconventional superconductivity or Bose-Einstein condensation of magnetic excitations observed in heavy fermion compounds, quantum spin systems, and antiferromagneti molecular wheels.The proposed project will address this matter via an experimental study of the low-temperature thermodynamic properties of ferromagnetic superconductors U",{"id":766,"funder":7,"programme":8,"title":767,"piName":10,"institution":768,"country":43,"year":13,"amount":10,"abstract":769},"cordis-marie-skłodowska-curie-actions-award-299996","Human pluripotent stem cells for modeling and correcting long-QT syndrome","ACADEMISCH ZIEKENHUIS LEIDEN","The long QT syndrome (LQTS) is an inherited or acquired disorder characterized by delayed ventricular repolarization predisposing affected individuals to fatal cardiac arrhythmias. In ~90% of the familial cases, LQTS is associated with mutation in two potassium voltage-gated channel genes: KCNQ1, causing LQT1, and KCNH2, causing LQT2. Since the first report of human induced pluripotent stem cells (hiPSC), lines have been obtained from patients with both genetic and sporadic diseases. LQT1- and L",{"id":771,"funder":7,"programme":8,"title":772,"piName":10,"institution":768,"country":43,"year":13,"amount":10,"abstract":773},"cordis-marie-skłodowska-curie-actions-award-303344","Explicitly Normalized ImaGing MAss Spectrometry","Imaging Mass Spectrometry is a rapidly developing technique that uses spatially resolved proteomic techniques to investigate a tissue’s biomolecular content. Imaging MS of pharmaceuticals has demonstrated that relative quantitation can be obtained if the MS response factors are known. However MS response factors for peptides and proteins are highly dependent on their exact nature. Despite it being acknowledged as the single biggest factor limiting the clinical application of the technique, to da",{"id":775,"funder":7,"programme":8,"title":776,"piName":10,"institution":777,"country":43,"year":13,"amount":10,"abstract":778},"cordis-marie-skłodowska-curie-actions-award-303137","Criminal Intelligence  in the EU","UNIVERSITEIT MAASTRICHT","By collecting, organizing and interpreting a vast bulk of data intelligence allows greater awareness of criminal threats and it permits law enforcement authorities to be more efficient in preventing and discovering crimes. Due to the growing importance of international intelligence cooperation, the European Union (EU) has taken action in the field.The present study focuses on criminal intelligence analysis, i.e. the process of interpreting information for mapping, foreseeing and discovering crim",{"id":780,"funder":7,"programme":8,"title":781,"piName":10,"institution":777,"country":43,"year":13,"amount":10,"abstract":782},"cordis-marie-skłodowska-curie-actions-award-299525","Toxicogenomic studies on engineered carbon nanomaterials","Engineered nanomaterials (ENM) are becoming an issue of great concern regarding their health effects. Different types of ENM are being used today in everyday consumer products as well as professional equipment such as medical devices. Several ENM, even those used in products that are already on the market, have been shown to be cytotoxic, genotoxic and immunotoxic in experimental settings, but knowledge is still too scarce and inconsistent for efficient and accurate risk assessment on ENM exposu",{"id":784,"funder":7,"programme":8,"title":785,"piName":10,"institution":777,"country":43,"year":13,"amount":10,"abstract":786},"cordis-marie-skłodowska-curie-actions-award-299086","Micro- and Macrocirculation Coupling: a cross sectional investigation of the cross-talk between the two circuits in insulin resistance states","Background: The human micro- and macrocirculation have distinct vital roles in the homeostasis of the cardiovascular system. There is a cross-talk between the two circuits to achieve the adequate vascular adaptations. Reciprocal transduction of ills signal between the micro- and macrocirculation may impair their optimal coupling and further accelerate vascular disease. In Europe the prevalence of insulin resistance (IR) (obesity and diabetes type 2) states and the related vascular damage and mor",{"id":788,"funder":7,"programme":8,"title":789,"piName":10,"institution":777,"country":43,"year":13,"amount":10,"abstract":790},"cordis-marie-skłodowska-curie-actions-award-272996","Negotiating local and global requirements in biomedical research; the case of biobanking","Biobanks are large scale storages of human tissue and data that are attributed a vital role as infrastructure for large scale genetic research. Biobanks can be used optimally if exchange of materials and data would be possible; however, many biobanks are established with local interests in mind and are therefore difficult to coordinate with each other. In this project I will explore how the tension between global and local affects 1. the input of materials and data, 2. the output of research res",{"id":792,"funder":7,"programme":8,"title":793,"piName":10,"institution":794,"country":678,"year":13,"amount":10,"abstract":795},"cordis-marie-skłodowska-curie-actions-award-298893","Constructing Sexuality and Gender in Czechoslovak Sexological Discourses during Communism (1948-1989)","Masarykova univerzita","Sexology enjoyed a special status under communism compared to other disciplines studying people and their relationships. While it was notbanned by the Party and some branches even flourished, the object of its study provided for certain marginalization. The proposed researchfocuses on two sets of questions: the first exploring the institutionalization and practical impact of Czechoslovak sexology in the communist period(1948-89) and its influence on shaping gendered understandings of individuals",{"id":797,"funder":7,"programme":8,"title":798,"piName":10,"institution":799,"country":83,"year":13,"amount":10,"abstract":800},"cordis-marie-skłodowska-curie-actions-award-302515","Artificial Cells for Enzyme Replacement Therapy for Phenylketonuria","AARHUS UNIVERSITET","Phenylketonuria (PKU) is the most common genetic enzyme defect, with an overall incidence in Europe and the USA of 1:10,000-20,000 live births per year. Patients suffer from a genetic defect in the liver enzyme phenylalanine hydroxylase (PAH), which normally metabolizes the amino acid phenylalanine (Phe) into the amino acid tyrosine. This specific enzyme defect, which results in an increase in the level of systemic Phe in the first few years of life, can lead to severe mental retardation. Herein",{"id":802,"funder":7,"programme":8,"title":803,"piName":10,"institution":799,"country":83,"year":13,"amount":10,"abstract":804},"cordis-marie-skłodowska-curie-actions-award-297727","Globalisation and the Education of Adults","The proposal’s objective is to identify and examine how globalisation processes are redefining the nature and scope of adult education in response to global challenges by asking the following research questions:1. How do political entities, interest groups and other actors influence the transnational policy development process and how, in turn, do they respond to transnational policies in adult education?2.How does international cooperation affect state policies concerning adult education, plann",{"id":806,"funder":7,"programme":8,"title":807,"piName":10,"institution":799,"country":83,"year":13,"amount":10,"abstract":808},"cordis-marie-skłodowska-curie-actions-award-298932","Nano-Voids in Strained Silicon for Plasmonics","The project aims at exploring the use of nanovoids and nanodots prepared as plasmonic structures to enhance the efficiency of Si single-crystalline photovoltaic (PV) devices. Fabrication and experimental investigation of plasmonic structures in strained Si\u002FSiGe multilayered structures will be carried to enhance light harvesting in solar cells due to both near-field and far-field effects. The main idea behind the production of nanovoids and nanodots is based on the ability of compressively strain",{"id":810,"funder":7,"programme":8,"title":811,"piName":10,"institution":812,"country":12,"year":13,"amount":10,"abstract":813},"cordis-marie-skłodowska-curie-actions-award-298642","Diaminations of Alkenes using Metal-free Chemistry","CARDIFF UNIVERSITY","Organic molecules of all shapes and sizes are required for a multitude of applications eg. in the biomedical, pharmaceutical, and agrochemical industries. Organic synthesis allows an insight into the way in which bonds between atoms can be formed or broken and how molecules can react with each other. Chemists are still faced with the challenge of converting simple, readily available molecules intocomplex structures as rapid, efficient, and cost-effective as possible. Therefore an increase in the",{"id":815,"funder":7,"programme":8,"title":816,"piName":10,"institution":817,"country":71,"year":13,"amount":10,"abstract":818},"cordis-marie-skłodowska-curie-actions-award-300376","Molecular Mechanisms of Natural Killer cell Cytotoxicity","KAROLINSKA INSTITUTET","The study of immunodeficiency syndromes such as familial hemophagocytic lymphohistiocytosis (FHL) and Griscelli Syndrome type 2 (GS2) has revealed a crucial role for Munc13-4, Stx11, Munc18-2 and Rab27a – members of protein families that regulate vesicle trafficking and membrane fusion – in cytotoxic granule exocytosis. Loss-of-function mutations in these proteins result in loss of target cell killing by NK cells and CD8+ T cells, resulting in a life-threatening sepsis-like condition. The precis",{"id":820,"funder":7,"programme":8,"title":821,"piName":10,"institution":817,"country":71,"year":13,"amount":10,"abstract":822},"cordis-marie-skłodowska-curie-actions-award-300355","Stress and the aging brain: the interplay between genetic susceptibility, aging and psychosocial stress on early symptoms of dementia","As the population is growing older, the risk for dementia increases. The complexity of dementia calls for a multidisciplinary approach",{"id":824,"funder":7,"programme":8,"title":825,"piName":10,"institution":826,"country":65,"year":13,"amount":10,"abstract":827},"cordis-marie-skłodowska-curie-actions-award-300544","Enhanced Climate Predictability involving the Subpolar gyre of the North Atlantic","UNIVERSITAET BERN","The project proposed here aims at improving the dynamical understanding of the subpolar gyre circulation in the North Atlantic Ocean. The primary research tools are numerical modeling and state-of-the-art statistical and physical analyses.Advance in this field is important because the subpolar gyre is a key region for decadal climate variability and therefore related to many changes that impact human societies and economies in this region. Demand for improved decadal predictions has increased in",{"id":829,"funder":7,"programme":8,"title":830,"piName":10,"institution":777,"country":43,"year":13,"amount":10,"abstract":831},"cordis-marie-skłodowska-curie-actions-award-300468","A Comparative North American-European Study on Two Anomalies to the Traditional Westphalian Nation State Model: Statelessness and Dual Nationality","Since 1993, all nationals of the EU Member States hold EU citizenship, which entails the right to move and reside freely within EU territory. Since 1999, immigration has been a matter of shared competence between the EU and its Member States. The EU increasingly faces the question whether this common immigration policy as well as the common status of EU citizenship do not also require harmonization of the rules on acquisition and loss of nationality, or even the transfer of national competences ",{"id":833,"funder":7,"programme":8,"title":834,"piName":10,"institution":835,"country":836,"year":13,"amount":10,"abstract":837},"cordis-marie-skłodowska-curie-actions-award-274678","The development of biologically active metal implants for improved osseointegration","UNIVERSITY OF GALWAY","IE","Osteoarthritis (OA) is the most common musculoskeletal disorder and affects approximately 355 million people world-wide. At present, no definitive cure exists for OA. Current treatment involves total joint replacement (TJR) which accounts for approximately 35% of arthritis related procedures. Presently more than 200,000 total knee replacements and 70,000 total hip replacements procedure are performed annually in the UK. One of the key aspects contributing to successful fixation is the rapid and ",{"id":839,"funder":7,"programme":8,"title":840,"piName":10,"institution":835,"country":836,"year":13,"amount":10,"abstract":841},"cordis-marie-skłodowska-curie-actions-award-299042","Synthesis and evaluation of new macrocyclic compounds based on jatrophane scaffold","AbstractJatrophane are natural compounds isolated from Euphorbia (Euphorbiaceae, spurge family). More than 150 jathrophane have been isolated so far. The general structure is an highly functionalized trans-bicyclo[10.3.0]pentadecane skeleton. Jatrophanes possess a variety of different biological activities such as inhibitory activity on the mammalian mitochondrial respiratory chain, cell cleavage arrest, cytotoxicity against various human cancer cell lines, antiviral activity, antiplasmodial act",{"id":843,"funder":7,"programme":8,"title":844,"piName":10,"institution":835,"country":836,"year":13,"amount":10,"abstract":845},"cordis-marie-skłodowska-curie-actions-award-271711","Locus specificity of immunoglobulin gene diversification","B cells distinguish themselves from all other cells, as they diversify their immunoglobulin (Ig) genes by hypermutation, gene conversion and switch recombination. All three processes required the expression of Activation Induced cytidine Deaminase (AID).The project aims to resolve the long-standing question why hypermutations are targeted almost exclusively to the Ig loci. Using the chicken B cell line DT40 as a model the fellow's laboratory previously identified a 10 kb cis-acting regulatory se",{"id":847,"funder":7,"programme":8,"title":848,"piName":10,"institution":849,"country":43,"year":13,"amount":10,"abstract":850},"cordis-marie-skłodowska-curie-actions-award-302428","TOwards Personalized medicine: defining the role of the bone marrow microenvironment in multiple myeloma","UNIVERSITAIR MEDISCH CENTRUM UTRECHT","Multiple myeloma (MM), the second most common hematological malignancies, is characterized by an expansion of malignant plasma cells (PCs) in the bone marrow (BM). Despite the development of novel therapies, MM remains an incurable disease with a 5-7 year survival expectancy. MM is usually proceeded by an asymptomatic premalignant state of clonal PC expansion, i.e. MGUS. Progression of MGUS to MM is a multistep process, which is partially dependent on the acquisition of genetic alterations. Howe",{"id":852,"funder":7,"programme":8,"title":853,"piName":10,"institution":854,"country":12,"year":13,"amount":10,"abstract":855},"cordis-marie-skłodowska-curie-actions-award-300596","'Re-presenting the 'Black Legend': conflict, coalition and the press in early modern Europe'","BRUNEL UNIVERSITY LONDON","This innovative project, to be carried out at Harvard University plus other significant Portuguese collections in Europe, explores the oldest diplomatic alliance in Europe (the ‘Treaty of Windsor’, 1386), which is technically still in force. It explores issues of religious conflict, xenophobia and political propaganda that remain issues in contemporary Europe, providing a historical perspective on European cultural and political integration.  Access to American archives and research expertise wi",{"id":857,"funder":7,"programme":8,"title":858,"piName":10,"institution":817,"country":71,"year":13,"amount":10,"abstract":859},"cordis-marie-skłodowska-curie-actions-award-298418","Brain mechanisms of human limb movement sense","Proprioception involves the sense of limb position and movement of body parts. It is critical for motor control, as without knowing where your body parts are it is impossible to move them accurately. Proprioception relies on the integration of various inputs, from muscle spindle receptors, Golgi tendon organs, skin stretch receptors, visual, auditory and vestibular inputs, and signals of motor command. How and where these signals are integrated in the human brain is still unclear.Here we will us",{"id":861,"funder":7,"programme":8,"title":862,"piName":10,"institution":863,"country":19,"year":13,"amount":10,"abstract":864},"cordis-marie-skłodowska-curie-actions-award-300545","Exploring bird distribution drivers across differentspatial scales and time to predict the potential impact of global change on bird distributions and diversity","MUSEUM NATIONAL D'HISTOIRE NATURELLE","Global change impacts on biodiversity, ecosystem processes and human well-being are a pressing scientific and political concern. One of the major goals of global change research is to reliably predict the future distributions of species and to assess potential resulting consequences for the adaptive management of ecosystems and their services and for conservation strategies. Dramatically increased availability of biodiversity data at broad scales, recent advances in statistical approaches such a",{"id":866,"funder":7,"programme":8,"title":867,"piName":10,"institution":849,"country":43,"year":13,"amount":10,"abstract":868},"cordis-marie-skłodowska-curie-actions-award-255170","Gram positive Surface proteins in immune evasion","The global incidence and rise of severe S. aureus infections accompanied by an alarming increase in antibiotic resistance warrants the development of novel treatment and vaccination strategies. This proposal combines the expertise of Dr. Nina van Sorge (Fellow) from the United States and the Prof. Jos van Strijp lab at the University Medical Center Utrecht in the Netherlands (Host institute). The Van Strijp lab is world leading in the identification and characterization of many secreted immune e",{"id":870,"funder":7,"programme":8,"title":871,"piName":10,"institution":872,"country":511,"year":13,"amount":10,"abstract":873},"cordis-marie-skłodowska-curie-actions-award-298257","Simulating the Dark Universe","ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA","One of the most challenging tasks for theoretical and observational cosmology in the next decade will be to understand the fundamental nature and properties of Dark Energy and Dark Matter. To this end, several ambitious observational programs are presently ongoing or have been planned for the near future, with the aim to reach unprecedented accuracy in the investigation of the dark sector of the Universe. The large wealth of high-quality data expected from these wide surveys will however require",{"id":875,"funder":7,"programme":8,"title":876,"piName":10,"institution":812,"country":12,"year":13,"amount":10,"abstract":877},"cordis-marie-skłodowska-curie-actions-award-297679","Targeting common mechanisms of pathogenesis in diseases of sterol homeostasis associated with lysosome dysfunction; development of novel and rapidly translatable clinical therapies","We have recently discovered a link at the cellular level between two rare pediatric diseases, Niemann-Pick C (NPC) and Smith-Lemli-Opitz Syndrome (SLOS). NPC is a disease where cholesterol and other lipids accumulate within the lysosome. SLOS is a multimalformation disease attributed to an inborn error of cholesterol synthesis, characterised by severe birth defects and neurological decline. Our data suggests that accumulation of a sterol precursor in patient-derived SLOS cells functionally inhib",{"id":879,"funder":7,"programme":8,"title":880,"piName":10,"institution":872,"country":511,"year":13,"amount":10,"abstract":881},"cordis-marie-skłodowska-curie-actions-award-302425","Beyond cynicism and bare life: practices of citizenship against migrants' inclusive exclusion","The proposed research addresses themes of current social relevance, such as the politics of migration and its governance, and their relation to emerging forms of engaged citizenship and sovereignty. The researcher shall investigate ethnographically modes of protest and solidarity that seek to contrast states' regulation of migrant movement (with a special focus on detention and deportation), and labour regimes based on the disposability of migrant bodies in contemporary Europe. Forms of resistan",{"id":883,"funder":7,"programme":8,"title":884,"piName":10,"institution":849,"country":43,"year":13,"amount":10,"abstract":885},"cordis-marie-skłodowska-curie-actions-award-302869","Towards FXR-mediated therapeutic intervention: Understanding how FXR integrates metabolic, endocrine and inflammatory signaling","Nuclear receptors (NRs) are ligand-activated transcription factors that play vital roles in human physiology. 13% of all FDA-approved drugs target NRs, however they are associated with side-effects that limit their utility and safety. These side-effects are attributed to general activation of all NR transcriptional actions. Understanding the molecular mechanisms of NR transcriptional functions is essential to improve rational NR drug design. This project will focus on FXR, the NR activated by bi",{"id":887,"funder":7,"programme":8,"title":888,"piName":10,"institution":817,"country":71,"year":13,"amount":10,"abstract":889},"cordis-marie-skłodowska-curie-actions-award-275270","Mechanisms of stem cell proliferation and senescence in the aged and damaged mouse brain","Stem cell self-renewal is a consequence of the ability to proliferate indefinitely while maintaining pluripotency. In the adult brain, neural stem cells continuously produce neurons, and its importance for memory and repair after neurodegeneration and brain damage has been extensively investigated. However, adult neurogenesis is limited and significantly decreases throughout life. With aging, increased senescence greatly restrains the neurogenic potential of aged stem cells. Senescence induction",{"id":891,"funder":7,"programme":8,"title":892,"piName":10,"institution":872,"country":511,"year":13,"amount":10,"abstract":893},"cordis-marie-skłodowska-curie-actions-award-299665","Settlement and Landscape Organisation of the Persepolis Region","The SELOPerse project aims to study the ancient Achaemenid occupation in the vicinity of the prestigious Unesco’s classified site of Persepolis (Iran, Fars province), one of the sumptuous royal residences built by King Darius I (520-486 BC). The project based on a new vision of the site organisation scheme as a kind of “garden city”. It means widespread settlement blocks ensuring the administrative and economic functions of what it was a provincial capital and sheltering the numerous inhabitants",200,{"programme":8,"total":896,"withPiName":897,"firstYear":898,"lastYear":899,"countryCount":900,"perYear":901,"topInstitutions":977,"topCountries":1053},26094,19,1988,2027,53,[902,904,907,910,913,916,919,922,925,928,931,933,936,939,942,945,948,951,954,957,960,963,966,969,972,975],{"year":898,"count":903},1,{"year":905,"count":906},2003,74,{"year":908,"count":909},2004,586,{"year":911,"count":912},2005,868,{"year":914,"count":915},2006,641,{"year":917,"count":918},2007,553,{"year":920,"count":921},2008,591,{"year":923,"count":924},2009,712,{"year":926,"count":927},2010,787,{"year":929,"count":930},2011,838,{"year":13,"count":932},901,{"year":934,"count":935},2013,1005,{"year":937,"count":938},2014,1009,{"year":940,"count":941},2015,1232,{"year":943,"count":944},2016,1231,{"year":946,"count":947},2017,1209,{"year":949,"count":950},2018,1353,{"year":952,"count":953},2019,1340,{"year":955,"count":956},2020,1314,{"year":958,"count":959},2021,1688,{"year":961,"count":962},2022,1362,{"year":964,"count":965},2023,1495,{"year":967,"count":968},2024,1522,{"year":970,"count":971},2025,1781,{"year":973,"count":974},2026,1532,{"year":899,"count":976},396,[978,981,984,987,990,993,996,999,1002,1005,1008,1011,1014,1017,1020,1023,1026,1029,1032,1035,1038,1041,1044,1047,1050],{"name":979,"count":980},"Centre National de la Recherche Scientifique CNRS",790,{"name":982,"count":983},"The Chancellor Masters and Scholars of the University of Cambridge",636,{"name":985,"count":986},"Kobenhavns Universitet",614,{"name":988,"count":989},"Chancellor, Masters and Scholars of the University of Oxford",579,{"name":991,"count":992},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",484,{"name":994,"count":995},"Imperial College of Science Technology and Medicine",428,{"name":997,"count":998},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",383,{"name":1000,"count":1001},"University of London",347,{"name":1003,"count":1004},"Katholieke Universiteit Leuven",280,{"name":1006,"count":1007},"The University of Birmingham",247,{"name":1009,"count":1010},"Eidgenoessische Technische Hochschule Zuerich",224,{"name":1012,"count":1013},"Aarhus Universitet",220,{"name":1015,"count":1016},"Universita Ca' Foscari  Venezia",219,{"name":1018,"count":1019},"University of Bristol",213,{"name":1021,"count":1022},"Ecole Polytechnique Federale de Lausanne",182,{"name":1024,"count":1025},"The University of Edinburgh",181,{"name":1027,"count":1028},"Universita Degli Studi di Padova",177,{"name":1030,"count":1031},"Universitat Wien",175,{"name":1033,"count":1034},"University of Leeds",169,{"name":1036,"count":1037},"Universiteit van Amsterdam",159,{"name":1039,"count":1040},"Universitetet I Oslo",156,{"name":1042,"count":1043},"Universiteit Utrecht",152,{"name":1045,"count":1046},"Technische Universiteit Delft",142,{"name":1048,"count":1049},"University of Warwick",141,{"name":1051,"count":1052},"Institut National de la Sante Et de la Recherche Medicale",139,[1054,1056,1058,1060,1062,1064,1066,1068,1070,1072,1074,1076,1078,1080,1083,1085,1087,1089,1091,1094,1097,1100,1103,1105,1108],{"name":12,"count":1055},5982,{"name":19,"count":1057},2854,{"name":30,"count":1059},2844,{"name":37,"count":1061},2362,{"name":511,"count":1063},2058,{"name":43,"count":1065},1624,{"name":83,"count":1067},1173,{"name":65,"count":1069},1075,{"name":251,"count":1071},996,{"name":71,"count":1073},788,{"name":77,"count":1075},634,{"name":836,"count":1077},608,{"name":521,"count":1079},487,{"name":1081,"count":1082},"PT",482,{"name":672,"count":1084},313,{"name":424,"count":1086},277,{"name":678,"count":1088},256,{"name":49,"count":1090},168,{"name":1092,"count":1093},"TR",147,{"name":1095,"count":1096},"PL",137,{"name":1098,"count":1099},"SI",113,{"name":1101,"count":1102},"CY",99,{"name":245,"count":1104},97,{"name":1106,"count":1107},"LU",59,{"name":1109,"count":1110},"LT",56]