[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-msca-postdoctoral-fellowship-2014":3,"awarded-stats-msca-postdoctoral-fellowship":889},{"awarded":4,"total":888},[5,15,20,24,30,35,41,47,51,55,61,67,72,76,82,87,92,98,103,109,114,120,125,130,136,141,145,149,154,161,166,172,176,180,186,190,194,199,203,207,212,216,220,224,229,234,238,243,247,251,255,259,263,267,271,275,279,283,287,291,295,299,303,307,311,315,319,324,328,332,336,341,345,349,353,358,362,366,370,374,378,382,386,391,395,400,405,409,413,417,421,425,429,434,438,442,446,450,454,458,462,466,470,474,478,482,486,490,494,498,502,506,512,516,520,524,528,532,536,540,545,549,554,558,562,566,570,574,578,582,587,592,596,600,604,608,613,617,623,627,633,637,642,646,650,654,658,663,667,671,675,679,683,688,692,696,700,704,708,712,716,721,725,729,733,737,742,746,750,754,758,763,767,772,776,780,784,789,794,798,802,807,812,816,821,825,829,833,837,841,845,849,853,857,861,865,869,874,878,883],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":10,"abstract":14},"cordis-marie-skłodowska-curie-actions-award-626474","Marie Skłodowska-Curie Actions","MSCA Postdoctoral Fellowship","Developing High Resolution Electron Spin Resonance (ESR) dating of fossil teeth: contribution to the chronology of early hominid occupations in the Mediterranean area",null,"CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA","ES",2014,"Electron Spin Resonance (ESR) is the only chronometric method that can be applied to date Early Pleistocene fossil teeth from early hominid occupations in the Mediterranean area.  Recent investigations focused on these old samples have highlighted the limitations of the standard procedures, as well as the complexity of the post depositional alteration processes in dental tissues at micro-scale.To overcome these issues, the present project proposes a cutting edge investigation that can only be pe",{"id":16,"funder":7,"programme":8,"title":17,"piName":10,"institution":18,"country":10,"year":13,"amount":10,"abstract":19},"cordis-marie-skłodowska-curie-actions-award-629004","The neural representations of person identity information: fMRI and neuropsychological investigations","UNIVERSITY COLLEGE LONDON","Person recognition is critical for appropriate social interactions, however we currently know very little about its neural basis. One possibility is that person knowledge is distributed in a network of modality-specific neural systems. Alternatively, Bruce & Young (1986) suggested a cognitive hierarchical model in which information from modality-specific recognition units (MRUs) is relayed to person identity nodes (PINs) containing or giving access to unified, amodal person representations. This",{"id":21,"funder":7,"programme":8,"title":22,"piName":10,"institution":18,"country":10,"year":13,"amount":10,"abstract":23},"cordis-marie-skłodowska-curie-actions-award-628959","Atlantic Late Bronze Age Interaction through Metal Hoards","The aim of this project is to examine the nature and the degree of interaction between the Late Bronze Age communities of the European Atlantic façade (c. 1300-850 BC) through the study of metal hoards. We propose to determine the similarities and differences expressed by the hoards in different spheres (economic, technological, ideological and religious) by undertaking an intensive and comparative study of the phenomenon in four selected geographical areas. To achieve this objective, priority w",{"id":25,"funder":7,"programme":8,"title":26,"piName":10,"institution":27,"country":28,"year":13,"amount":10,"abstract":29},"cordis-marie-skłodowska-curie-actions-award-331728","Banking Market Structure and Firms Financing in Financial Turmoil”","INSTITUT FUER ANGEWANDTE WIRTSCHAFTSFORSCHUNG EV","DE","The proposal aims to investigate the existing relationship between banking market structures (e.g. banks’ headquarter location, efficiency and banks board of directors ) and the supply of credit to non-financial firms  by looking and comparing German, French and Italian banking systems during financial turmoil. In particular, I disentangle the effects of specific characteristics of financial markets at local market level, distinguishing the factors that may have driven differences in the severit",{"id":31,"funder":7,"programme":8,"title":32,"piName":10,"institution":33,"country":28,"year":13,"amount":10,"abstract":34},"cordis-marie-skłodowska-curie-actions-award-331333","Proximity Enhanced Energy Harvesting of Multi-Axis Motion","ALBERT-LUDWIGS-UNIVERSITAET FREIBURG","Proximity Enhanced Energy harvesting of multi-axis motion (ProxEE) is a proposal to design, model, fabricate and test a class of inertial micro energy harvesters that convert multidimensional and non-periodic human motion into electrical energy for powering body worn and medical devices. The harvester uses a spring-less spherical magnetic proof mass to capture kinetic energy from the user, after which an array of transducer ‘cells’ employing a novel actuation method are used to convert the mecha",{"id":36,"funder":7,"programme":8,"title":37,"piName":10,"institution":38,"country":39,"year":13,"amount":10,"abstract":40},"cordis-marie-skłodowska-curie-actions-award-626734","Implications of the mesopelagic Remineralization for the OceaN Iron Cycle","UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6","FR","The bioavailability of iron (Fe) has been shown to limit primary production in up to 50% of the ocean’s waters. As a result of its function in modulating Earth’s climate, the role of Fe supply on the oceanic carbon cycle has received widespread attention over the last two decades. However, much of the research to date has focused new sources Fe, and little attention has been directed toward controls on the supply of recycled Fe. Within the mesopelagic zone (the layer underlying the euphotic zone",{"id":42,"funder":7,"programme":8,"title":43,"piName":10,"institution":44,"country":45,"year":13,"amount":10,"abstract":46},"cordis-marie-skłodowska-curie-actions-award-623085","Nonequilibrium quantum fluctuations in superconducting devices","SCUOLA NORMALE SUPERIORE","IT","In the last fifteen years we have witnessed to an impetuous advancement in the theory of nonequilibrium fluctuations, triggered by the discovery of a number of relations, collectively known as Fluctuation Theorems, which link the full nonlinear response to equilibrium thermodynamic properties. Experimental investigations of these exact relations in the quantum regime is yet in its infancy, while we are currently witnessing a growing interest into these relations by the experimental condensed mat",{"id":48,"funder":7,"programme":8,"title":49,"piName":10,"institution":18,"country":10,"year":13,"amount":10,"abstract":50},"cordis-marie-skłodowska-curie-actions-award-622661","Interests, demands and network ties in Brussels: explaining interest groups' lobbying success across EU policy areas","The project aims to examine interest groups’ participation in EU policymaking and to investigate a fundamental question regarding the EU interest representation system: under what conditions are interest groups’ policy demands integrated into the policymaking process and translated into policy outcomes? In other words, what factors explain interest groups’ success in influencing the content of EU legislative proposals?The project aims to answer this question by examining interest groups’ lobbyin",{"id":52,"funder":7,"programme":8,"title":53,"piName":10,"institution":33,"country":28,"year":13,"amount":10,"abstract":54},"cordis-marie-skłodowska-curie-actions-award-624520","The Nazis’ Foreign Experts:European Academics and Professionals and the SS’s “New Order”, 1939-1945","I am applying to the Marie Curie IEF to research how young North-Western Europeans (from the Scandinavian countries, Holland and Switzerland) envisioned their countries’ economic and political relationship to Nazi Germany and the occupied Eastern territories and how these beliefs translated into concrete efforts to support the regime. Numerous studies exist that examine how the SS and young German scientists and academics began to radically transform Europe, often with genocidal consequences. Ho",{"id":56,"funder":7,"programme":8,"title":57,"piName":10,"institution":58,"country":59,"year":13,"amount":10,"abstract":60},"cordis-marie-skłodowska-curie-actions-award-330255","Observation of the Higgs production mode in the ttH channel at ATLAS","ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE","UK","On the 4th of July 2012, the ATLAS and CMS experiments at CERN independently announced the discovery of a “Higgs-like” particle. This remarkable discovery is of tremendous importance to our understanding of the Universe. The discovered particle cannot yet be confirmed as the Higgs boson because several of its properties must be measured and compared with the theoretical predictions.In the proposed programme, the fellow aims to address the nature of the “Higgs-like” particle by measuring some of ",{"id":62,"funder":7,"programme":8,"title":63,"piName":10,"institution":64,"country":65,"year":13,"amount":10,"abstract":66},"cordis-marie-skłodowska-curie-actions-award-327196","Cortical Mechanisms of Exploratory Learning","University of Zurich","CH","In daily life, the trade-off between exploration of alternative opportunities and exploitation of the benefits of the choice at hand is encountered often. While the ability of mammals to switch to explorative courses of action has been extensively studied in machine learning and ethology fields, much less attention in neuroscience has been given to understanding how the brain mediates such decisions in humans. To date, no mechanism has been put forward. The proposed project seeks to understand h",{"id":68,"funder":7,"programme":8,"title":69,"piName":10,"institution":70,"country":12,"year":13,"amount":10,"abstract":71},"cordis-marie-skłodowska-curie-actions-award-627784","A Universal Model of Word Comprehension","BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE","The proposed research will develop a “universal” connectionist architecture and a set of models capable of handling key cross-linguistic differences across English, Spanish, and Hebrew.  This work is complemented with targeted empirical investigations.Computational Investigations.  I will develop improved connectionist models which employ more general architectural assumptions and that are able to learn to comprehend words from languages that impose different division of labour between orthograp",{"id":73,"funder":7,"programme":8,"title":74,"piName":10,"institution":18,"country":10,"year":13,"amount":10,"abstract":75},"cordis-marie-skłodowska-curie-actions-award-329465","A Theory of Asymmetrical Warfare: normative, legal, and conceptual issues","The project takes as its point of departure the recent changes in the character of war and aims to develop a systematic theory of asymmetrical warfare which is both morally persuasive and legally feasible. It is organized around three core thematic areas. First, it examines, comparatively, how the law regulates international and non-international armed conflicts, and the participation of mercenaries, private security companies, paramilitary groups, terrorist organizations, and civilians who dire",{"id":77,"funder":7,"programme":8,"title":78,"piName":10,"institution":79,"country":80,"year":13,"amount":10,"abstract":81},"cordis-marie-skłodowska-curie-actions-award-626398","ReVINK","Instytut Podstaw Informatyki Polskiej Akademii Nauk","PL","Verification is an important technique to ensure quality of a system and detect scenarios in which requirements can be violated. For complex systems with multiple interacting components, one of the crucial requirements is a component's ability to achieve a given goal. However, verification of strategic abilities is computationally hard, and the existing model checking algorithms cope with it only partially. This applies especially to systems where components have limited knowledge of the global ",{"id":83,"funder":7,"programme":8,"title":84,"piName":10,"institution":85,"country":28,"year":13,"amount":10,"abstract":86},"cordis-marie-skłodowska-curie-actions-award-622322","GOAl - Groups and operator algebras","Westfälische Wilhelms-Universität Münster","The goal of this research project is to clarify the relation between locally compact groups and their associated von Neumann and C*-algebras.  I have three objectives.First, I want to understand general criteria for a locally compact group G implying that its group von Neumann algebra L(G) is a non-amenable factor.  Ideally, I will find a characterisation of such groups.Second, I want to find C*-superrigid groups, that is discrete groups G such that any other discret group whose reduced C*-algeb",{"id":88,"funder":7,"programme":8,"title":89,"piName":10,"institution":90,"country":28,"year":13,"amount":10,"abstract":91},"cordis-marie-skłodowska-curie-actions-award-625032","Democratization and Transnational Human Rights Regimes: A Case Study of Turkey and the European Court of Human Rights","HERTIE SCHOOL GEMMEINNUTZIGE GMBH","The proposed research project is concerned with the interaction between the European Court of Human Rights (ECtHR) and Turkey, and seeks to contribute to the understanding of the Turkish case by looking through the ECtHR lens and of the European human rights system through the Turkish lens. The project will be based on an empirical analysis of the impact of the ECtHR’s case law on democracy in Turkey based on the following typology of issues: 1) rights associated with ethno-linguistic group memb",{"id":93,"funder":7,"programme":8,"title":94,"piName":10,"institution":95,"country":96,"year":13,"amount":10,"abstract":97},"cordis-marie-skłodowska-curie-actions-award-629388","Re-Engineering Europe's STEM Pipeline","INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH","IE","The EU faces an alarming deficit of engineers—in 2011 Germany fell 76,400 engineers short. To address this and diversify perspectives, the EU must attract and retain more women in science, technology, engineering, and mathematics (STEM). Findings of research I conducted as a Fulbright to Ireland in Engineering Education indicate Project-Based Learning (PBL) increases student engagement and many help address reasons women avoid STEM subjects.Today, there is a gap in understanding why women chose ",{"id":99,"funder":7,"programme":8,"title":100,"piName":10,"institution":101,"country":28,"year":13,"amount":10,"abstract":102},"cordis-marie-skłodowska-curie-actions-award-626656","Niya Tocharian: language contact and prehistory on the Silk Road","BERLIN-BRANDENBURGISCHE AKADEMIE DER WISSENSCHAFTEN","Niya Prakrit or Niya Gāndhārī is a Middle Indian language from the 3rd and 4th centuries CE. Having its origins in Northern Pakistan, it came to the southern oases of the Tarim Basin in present-day North-West China, where it was the administrative language of the Shànshàn kingdom, a short-lived state on the Silk Road. The language is named after the archaeological site Niya in the Shànshàn area, where over 750 documents were found, written in the Niya Prakrit language and in the Kharoshthī scrip",{"id":104,"funder":7,"programme":8,"title":105,"piName":10,"institution":106,"country":107,"year":13,"amount":10,"abstract":108},"cordis-marie-skłodowska-curie-actions-award-624864","A structural mechanism of photoreceptor protein signalling by time-resolved anisotropic X-ray solution scattering","GOETEBORGS UNIVERSITET","SE","Photoreceptor proteins are light sensing biomolecules used by bacteria, funghi and plants to react to light stimuli. To date, a range of light-signalling proteins and their function are known. However, the mechanisms of signal propagation from the light sensitive chromophore to the signalling cascade in the cell are still elusive.Protein crystallography is an established method to gain structural information on static protein conformations. Only recently, time-resolved X-ray scattering methods f",{"id":110,"funder":7,"programme":8,"title":111,"piName":10,"institution":112,"country":45,"year":13,"amount":10,"abstract":113},"cordis-marie-skłodowska-curie-actions-award-328796","Autodigestion in Hemorrhagic Shock and Acute Heart Failure: a Cell-to-System Approach to Pathophysiology and Therapy","POLITECNICO DI MILANO","The relationship between hemorrhagic shock, systemic inflammatory response syndrome, and multiple organ failure has long been investigated, but no accepted tissue injury mechanism has been assessed. This shortage of understanding of the basic pathophysiology limits the clinical management of one of the most important medical conditions from a mortality point of view, with implications in anesthesia and critical care.In this proposal, a new approach to the study of the molecular triggers of shock",{"id":115,"funder":7,"programme":8,"title":116,"piName":10,"institution":117,"country":118,"year":13,"amount":10,"abstract":119},"cordis-marie-skłodowska-curie-actions-award-626147","Fluorescence Analysis and Monitoring of Recirculating Aquaculture Systems","DANMARKS TEKNISKE UNIVERSITET","DK","FAMoRAS aims to provide a rapid, reliable, and novel tool for the optimisation of Recirculating Aquaculture Systems (RASs) using fluorescence spectroscopy, to greatly improve the production abilities of EU fish farming industries.Aquaculture plays an important role in the production of sustainable international food sources. These marine farming systems provided 47% of the world’s fish stocks in 2006 and more than 50% in 2012.  However due to the inherent density of fish within these systems, in",{"id":121,"funder":7,"programme":8,"title":122,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":124},"cordis-marie-skłodowska-curie-actions-award-327905","Toward the Understanding of Stereopsis Recovery and its Application for an Amblyopia Treatment","CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS","Stereopsis is the perception of depth through the differences between the two eye images (binocular depth cues). A substantial proportion of adults cannot process those cues correctly. In a recent experiment, stereoblind observers recovered stereopsis in a perceptual learning task in which binocular depth cues are mixed with monocular depth cues. Stereopsis was recovered durably so that observers could experience stereoscopic depth in 3D movie theatres and everyday life for the first time. We pr",{"id":126,"funder":7,"programme":8,"title":127,"piName":10,"institution":128,"country":28,"year":13,"amount":10,"abstract":129},"cordis-marie-skłodowska-curie-actions-award-625720","Dynamic spatial organization of plasma membrane proteins at the nanoscale","JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG","Besides its function as a passive cell wall plasma membrane (PM), involved in signal transduction and cell adhesion, is essential to enable the formation of tissues. Understanding PM function requires molecular insights into its dynamic spatial organization. Recent studies show that membrane proteins rearrange laterally forming nanoclusters of various size. On the other hand, a hierarchical model of two dimensional PM organization has been proposed including transient confinement in membrane-act",{"id":131,"funder":7,"programme":8,"title":132,"piName":10,"institution":133,"country":134,"year":13,"amount":10,"abstract":135},"cordis-marie-skłodowska-curie-actions-award-328967","The Post-Theory Moment of Body:Re-materializing the Corporeal, Bridging Critical Idioms, Conceptualizing Art","UNIVERSITY OF CYPRUS","CY","This project seeks to study the role, uses and transformations of the body within the contemporary reflection on post-Theory. It builds on contemporary work on post-Theory and on body-related issues in Anglo-American academic context, and it opens up to the French post-Theory movement, the German Kulturwissenschaft, philosophical life-narratives, body-oriented art discourses, and theoretical reflection on the senses. The project examines the body as a perpetually re-theorized political entity, a",{"id":137,"funder":7,"programme":8,"title":138,"piName":10,"institution":106,"country":107,"year":13,"amount":139,"abstract":140},"cordis-marie-skłodowska-curie-actions-award-627794","Antibody-responses to Helicobacter pylori and tumour proteins as biomarkers for early gastric cancer","€390,265","This proposal concerns an outgoing fellowship for Samuel Lundin (SL), PhD, Dept. of Microbiology and Immunology, University of Gothenburg. To further develop and substantially boost his scientific career, SL will for two years visit the laboratory of Professor Barry Marshall, University of Western Australia, Perth, Australia.SL has a good track record in science, but lacks crucial skills in bioinformatics and H. pylori genomics. The fellowship at the Marshall group will alleviate this and thereb",{"id":142,"funder":7,"programme":8,"title":143,"piName":10,"institution":106,"country":107,"year":13,"amount":10,"abstract":144},"cordis-marie-skłodowska-curie-actions-award-625308","Adaptation and evolution of wild alfalfa: a genomic approach","The Eurasian genus Medicago is best known for the perennial species M. sativa (alfalfa). Alfalfa is the world’s oldest, most important, and most intensively studied fodder crop. There is huge promise for extending the importance of alfalfa well beyond its present primary use as a feed for livestock. This species has potential uses in several domains such as:  pharmaceuticals, biodegradable plastics, biofuels, textiles, and human nourishing. Medicago sativa is a polymorphic species with a variati",{"id":146,"funder":7,"programme":8,"title":147,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":148},"cordis-marie-skłodowska-curie-actions-award-623637","Dynamics of Confined Complex Suspensions","Soft condensed materials are ubiquitous in nature: from polymer melts to a human cell. These systems are characterized by complex order on mesoscale, a length scale a lot larger than the individual building blocks (e.g. atoms or molecules) but smaller than can be seen by naked eye. Examples of complex soft materials are provided by colloidal systems - 0.1-10 micron particles suspended in a homogeneous fluid or liquid crystals (LCs) which can have order (orientational\u002Ftranslation) but can flow li",{"id":150,"funder":7,"programme":8,"title":151,"piName":10,"institution":152,"country":59,"year":13,"amount":10,"abstract":153},"cordis-marie-skłodowska-curie-actions-award-627658","Keeping ready for battle: understanding fundamental mechanisms of establishment and maintenance of epigenetic marks underlying abiotic stress memory in plants","UNIVERSITY OF GLASGOW","Drought and salt stress threaten crop production worldwide. Evidence from the field that pre-exposure of plants to transient mild stress (priming) enhances their tolerance to subsequent harsher stress indicates that plants maintain a ‘memory’ of environmental events that allows them to respond more efficiently to subsequent stress. However, systematic studies on the molecular processes underlying abiotic stress priming are scarce. The proposed project takes advantage of an effective salt-priming",{"id":155,"funder":7,"programme":8,"title":156,"piName":10,"institution":157,"country":158,"year":13,"amount":159,"abstract":160},"cordis-marie-skłodowska-curie-actions-award-329870","“Adaptation to cyanobacteria through the symbiotic microbiota in the waterflea Daphnia”","KATHOLIEKE UNIVERSITEIT LEUVEN","BE","€177,000","Metazoans are ubiquitously associated with microbial symbionts, which can provide direct benefits to their hosts, such as nutrients provisioning, protection against environmental stress, or enhancement of host digestive abilities. These microbial mutualists have the ability to adapt rapidly to changing environments, and could potentially play a key role in the local adaptation of their host, especially in the context of rapid environmental changes imposed by human activities. However, despite th",{"id":162,"funder":7,"programme":8,"title":163,"piName":10,"institution":164,"country":158,"year":13,"amount":159,"abstract":165},"cordis-marie-skłodowska-curie-actions-award-626959","Integrated Bio-Electrochemical Production of Ethylene through CO2 sequestration","VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.","Globally, accumulation of carbon dioxide (CO2) in atmosphere from various anthropogenic and natural sources is increasing causing threat of global warming. At the same time, industrial production of various commodity chemicals demanding carbon based raw materials through exploitation of different natural resources of the earth is causing an imbalance in the earth’s ecosystem. Recent research on microbial electrosynthesis has shown the conversion of CO2 into useful organic chemicals. Electrochemi",{"id":167,"funder":7,"programme":8,"title":168,"piName":10,"institution":169,"country":170,"year":13,"amount":10,"abstract":171},"cordis-marie-skłodowska-curie-actions-award-621970","Imperial Ambassadresses between the Courts of Madrid and Vienna (1650-1700): Diplomacy, Sociability and Culture","UNIVERSITAT WIEN","AT","The aim of my project is to analyse the diplomatic and cultural role of the Imperial ambassadresses in the court of Madrid, along with the impact of their posts upon their subsequent lives in the court of Vienna. The chosen time frame is the second half of the 17th century, a period in which the foreign relations between the Spanish Monarchy and the Empire were marked by the so-called question of succession.The new diplomatic history dedicated to the early modern period has paid little attention",{"id":173,"funder":7,"programme":8,"title":174,"piName":10,"institution":169,"country":170,"year":13,"amount":10,"abstract":175},"cordis-marie-skłodowska-curie-actions-award-626025","Reconstructing conditions during dolomite formation in evaporative Triassic environments","Dolomite is besides calcite the most abundant carbonate mineral in the geological record. However, the conditions and mechanisms of its formation are poorly understood. Most dolomite is considered to have formed at elevated temperatures when sediments became deeply buried over geological time scales. Abundant dolomite occurs in shallow marine carbonate deposits of the ancient Triassic Tethys margin, which today forms part of the Eastern and Southern Alps. Hitherto evidence indicates that some of",{"id":177,"funder":7,"programme":8,"title":178,"piName":10,"institution":117,"country":118,"year":13,"amount":10,"abstract":179},"cordis-marie-skłodowska-curie-actions-award-327565","Studies of Polynuclear Clusters for Biomass Conversion","There are four main objectives:1) Study the chemical performance of the multidentate amino ligand supported tri- and hexanuclear iron clusters developed by the Betley group. The clusters will be subjected to CO, CO2 and MeOH.2) Construct novel cluster designs by ligand manipulations. Synthesise new hexanucleating and odd valued nucleating ligands.3) Apply the accumulated knowledge on cluster chemistry and their unique properties to use them as mediators for actual organic chemical group transfor",{"id":181,"funder":7,"programme":8,"title":182,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":185},"cordis-marie-skłodowska-curie-actions-award-332395","Towards gene identification and personalized prophylactic medication for lithiopathies in lithium-using patients","STICHTING RADBOUD UNIVERSITEIT","NL","Lithium is widely prescribed and the mainstay treatment for bipolar disorders. Unfortunately, lithium treatment often leads to adverse side effects (lithiopathies) like hypercalcaemia, nephrogenic diabetes insipidus and chronic kidney disease.Despite the above lithiopathies, cessation of lithium therapy is not an option for most patients, because there is no good alternative and the bipolar disorder has a larger impact on the patient’s quality of life. However, rationally-based medication for li",{"id":187,"funder":7,"programme":8,"title":188,"piName":10,"institution":152,"country":59,"year":13,"amount":10,"abstract":189},"cordis-marie-skłodowska-curie-actions-award-626571","Archaeology and an integrated approach to landscape governanceDevelopment of an Integrated Landscape Character Appraisal Method (ILCA)","ILCA is a 24 month research training project involving international and inter-sector mobility within Europe. To undertake the project, the researcher will move from Greece to the United Kingdom and move between sectors, transferring from her current position in the third sector, with the landscape and environment NGO Med-INA, to the academic sector at the University of Glasgow.The project is based on the idea that the integrated characterisation of a landscape - and particularly of the landscap",{"id":191,"funder":7,"programme":8,"title":192,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":193},"cordis-marie-skłodowska-curie-actions-award-327340","Multi-Modal Functional Fingerprint of the Human Brain. Application in ADHD","The functional magnetic resonance imaging (FMRI) community is shifting its interest from localizing functions to capturing functional brain networks. To investigate the functional network architecture of the brain neuroimagers are studying the brain’s spontaneous activity using resting state FMRI (R-FMRI). Both ease-of-use and the distributed nature of the network readouts are contributing to the popularity of R-FMRI for studying clinical populations. Studies increasingly report aberrant functio",{"id":195,"funder":7,"programme":8,"title":196,"piName":10,"institution":197,"country":184,"year":13,"amount":10,"abstract":198},"cordis-marie-skłodowska-curie-actions-award-627959","robotICs: do autonomous robots benefit from an Intermittent Control (IC) implementation?","TECHNISCHE UNIVERSITEIT DELFT","Robotics is predicted to be the next big step in the digital revolution. Therefore, Europe should keep a globally leading position in this much promising arena. One problem in robotics is that state-of-the-art humanoids still cannot stand ground in environments that we humans easily confront. Our proposal deals with the challenging solution of replicating the adaptability and flexibility of human motor control.  Here we propose a specific robotics implementation of our bio-inspired Intermittent ",{"id":200,"funder":7,"programme":8,"title":201,"piName":10,"institution":157,"country":158,"year":13,"amount":10,"abstract":202},"cordis-marie-skłodowska-curie-actions-award-625551","To the roots of induced systemic resistance in the Arabidopsis-Trichoderma-Fusarium tripartite interaction","Biological control organisms (BCOs) can form an important component of more sustainable agriculture. Trichoderma spp. are soil fungi with great potential in this respect. They can trigger induced systemic resistance (ISR) in the plant, leading to a more rapid and robust systemic activation of defense when the plant is subsequently challenged by a pathogen. However, genome-wide investigations of the tripartite plant-Trichoderma-pathogen interaction are scarce, although they provide substantial no",{"id":204,"funder":7,"programme":8,"title":205,"piName":10,"institution":117,"country":118,"year":13,"amount":10,"abstract":206},"cordis-marie-skłodowska-curie-actions-award-629202","Energizing Futures: Investigating the Infusion of IT and Design into Novel Foresight Practices","This project advances applied and theoretical research into novel foresight methods. Taking the governance of emerging energy technologies as a case, this research investigates scenarios mediated through cutting-edge gaming, visualization, simulation and design techniques. This project involves two phases of qualitative research to empirically investigate the make-up, impact and products of novel foresight methods employed in the energy sector. Drawing on perspectives of anticipation, materialit",{"id":208,"funder":7,"programme":8,"title":209,"piName":10,"institution":157,"country":158,"year":13,"amount":210,"abstract":211},"cordis-marie-skłodowska-curie-actions-award-623253","DOT1L in Osteoarthritis","€169,800","The DOTOS project will study the role of DOT1L in synovial joint development,  homeostasis and disease with specific attention towards osteoarthritis (OA), one of the most common chronic diseases.We identified an association between the DOT1L (DOT1-like histone H3 methyltransferase) gene and OA. Histone methylation is a regulator of gene transcription. Some histone methylations result in increased gene expression, e.g. lysine methylation at lysine 79 in histone 3 (H3K79). DOT1L is the only known",{"id":213,"funder":7,"programme":8,"title":214,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":215},"cordis-marie-skłodowska-curie-actions-award-624380","On the neural basis of working memory:How the brain retains information in the face of distraction","Every time we open our eyes, we are bombarded with visual information. At the same time, we need to retain previously observed information to keep track of our goals and whereabouts. How can we remember relevant visual information when we are continuously processing new information? Recent studies have shown that when we have to maintain visual information over a short delay period, our visual system that deals with the initial processing of stimuli is recruited to keep representations active. H",{"id":217,"funder":7,"programme":8,"title":218,"piName":10,"institution":197,"country":184,"year":13,"amount":10,"abstract":219},"cordis-marie-skłodowska-curie-actions-award-621974","Development of Advanced Magnetic Filtration System for Industrial Lubricants","Scope of proposed research include the sustainable design and development of advanced magnetic filtration systems and modelling of their behaviour that will assist to achieve a step change in fluid management technology used in industrial lubricant filtration systems, for example metalworking and washing process. The emphasis of the research lies in the development and validation of industrial prototype of media-free magnetic system that can capture and recycle fine particulates and contaminatio",{"id":221,"funder":7,"programme":8,"title":222,"piName":10,"institution":157,"country":158,"year":13,"amount":210,"abstract":223},"cordis-marie-skłodowska-curie-actions-award-624296","VAD-Patient interaction: from rest to exercise","Heart failure is the first cause of death in industrialized countries. Despite the use of medical therapy a certain percentage of patients (PTs) will progress to end stage heart failure. In this case the ventricular assist device (VAD) is a viable therapy that nowadays is used increasingly not only as a bridge to transplantation, but also as destination therapy and as a bridge to recovery. Therefore, there is a clinical need to understand how to estimate and modulate the optimal level of support",{"id":225,"funder":7,"programme":8,"title":226,"piName":10,"institution":227,"country":28,"year":13,"amount":10,"abstract":228},"cordis-marie-skłodowska-curie-actions-award-628603","The role of epithelial sodium channels in adult neural stem cells","HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH","During adulthood, new neurons are generated by so called adult neurogenesis in the subgranular zone (SGZ) of the hippocampus and in the subventricular zone (SVZ) of the lateral ventricles. In these neurogenic niches, the adult neural stem cells (aNSCs) generate new neurons that are critical for establishing factual memories and mood control. Regulation of aNSCs is critical for cognitive brain functions and for development of future cell-based therapies of neurodegenerative diseases. While geneti",{"id":230,"funder":7,"programme":8,"title":231,"piName":10,"institution":232,"country":39,"year":13,"amount":10,"abstract":233},"cordis-marie-skłodowska-curie-actions-award-624543","Development of a new generation of highly scalable and accurate 3D Particle-In-Cell codes","COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES","The success of PetaWatt (PW) laser facilities presently under construction, which aim at producing promising particle and light sources from relativistic laser-plasma interactions, will rely on the strong coupling between experiments and large-scale simulations with  Particle-In-Cell (PIC) codes.Standard PIC codes currently in use fail to accurately describe these new interaction regimes because the finite difference Maxwell’s solver used to compute electromagnetic fields generates strong instab",{"id":235,"funder":7,"programme":8,"title":236,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":237},"cordis-marie-skłodowska-curie-actions-award-623072","The neural implementation of contextual influences in speech perception","Human listeners can perceive speech quite effortlessly, although it is, computationally, a very challenging task. An important reason why humans perform so well is because they make use of acoustic information that is available in the context. Such contextual information is useful because it provides a listener with information about a speaker's voice properties and his or her speaking rate. Although the influence of context on speech perception was noted decades ago and has been extensively inv",{"id":239,"funder":7,"programme":8,"title":240,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":242},"cordis-marie-skłodowska-curie-actions-award-628585","The contribution of cellular adhesions to matrix remodeling in health and disease","EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH","Tissues in the human body are exposed to cyclic loading and have the capacity to adapt, to meet new loading demands. Cells facilitate such adaptation by responding to mechanical triggers, which depends on the balance between endogenous tension (cellular forces) and exogenous tension (matrix stiffness and resistance to stretch). This is regulated by matrix adhesions: the cellular force sensors. In healthy tissue, cells can positively contribute to tissue functioning by synthesizing additional mat",{"id":244,"funder":7,"programme":8,"title":245,"piName":10,"institution":169,"country":170,"year":13,"amount":10,"abstract":246},"cordis-marie-skłodowska-curie-actions-award-624577","Employing the Cultural Broker in the Governance of Migration and Integration","This project brings together a researcher with excellent knowledge in the fields of migration, NGOs, and diversity and a background in qualitative research methods with the substantial expertise of the host institution in transnationalism, grounded theory and comparative approaches in order to develop an innovative methodological and analytical framework to study the role of migrant employees as cultural brokers in the governance of migration and integration and to train the researcher’s skills ",{"id":248,"funder":7,"programme":8,"title":249,"piName":10,"institution":169,"country":170,"year":13,"amount":10,"abstract":250},"cordis-marie-skłodowska-curie-actions-award-327063","Localized Frame Expansions in Time-Scale Analysis","A frame expansion is a representation of a general signal (function) as a weighted superimposition of basic building blocks. Diverse operations on functions can be understood by first considering their action on these basic atoms. Similarly, several subtle properties of functions (e.g. smoothness, decay, directional regularity) are encoded in the coefficients (weights) involved in the representation.The usefulness of frame expansions, both in theory and applications, comes from the possibility o",{"id":252,"funder":7,"programme":8,"title":253,"piName":10,"institution":133,"country":134,"year":13,"amount":10,"abstract":254},"cordis-marie-skłodowska-curie-actions-award-625892","A Level-1 Tau Trigger for CMS at HL-LHC","The leading scientific breakthrough of 2012 came from the Large Hadron Collider (LHC) experiments, which provided evidence for the existence of a Higgs boson in the mass region of ~126 GeVc-2. This discovery, made by the ATLAS and CMS Experiments at CERN, has finally brought the High-Energy Physics community to the Higgs Era. In order to build on this discovery, the LHC is planning for an immensely exciting science programme known as the high-luminosity upgrade (HL-LHC). The HL-LHC is planned fo",{"id":256,"funder":7,"programme":8,"title":257,"piName":10,"institution":152,"country":59,"year":13,"amount":10,"abstract":258},"cordis-marie-skłodowska-curie-actions-award-623027","Natural responses to past North Atlantic Oscillations: Southern Iberian Peninsula vs. United Kingdom. Analogues for future environmental changes","The overall theme of this proposal is to reconstruct ancient environments using multidisciplinary approaches to understand the past, the present, and, if it is possible, predict the future. In general terms, I propose to study the organic geochemical and isotopic composition of biomarkers in lacustrine and peat bog sediments from two key regions: southern Iberian Peninsula and the United Kingdom, in order to decipher the climatic changes occurred during the Holocene (last 10 kyrs), the natural r",{"id":260,"funder":7,"programme":8,"title":261,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":262},"cordis-marie-skłodowska-curie-actions-award-624125","Trojan-Lipid-Sensor","Modulation of leukocyte adhesiveness is critical to leukocyte function during the immune response. In order to extravasate from the blood stream, leukocyte rolling must be followed by integrin-mediated rapid arrest. Intergins play a crucial role on chemokine-induced arrest of leukocytes on blood vessels. Signaling events mediating adhesion are extensively studied. Increasing evidence underlays the essential role of lipid second messenger as important fine regulators of signaling cascade leading ",{"id":264,"funder":7,"programme":8,"title":265,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":266},"cordis-marie-skłodowska-curie-actions-award-621992","Localized objects formed by self-trapped gravitational waves","This project aims to investigate geon-type solutions in Einstein's theory of Gravitation. Geons are reminiscent of stars, consisting of self-trapped nonlinear gravitational waves, in some sense they are gravitational wave stars. A very important application of geons, provided they have good stability properties and sufficiently long lifetimes, is that they can provide a natural component for the mysterious dark matter content of the Universe without invoking unobserved new type of matter fields.",{"id":268,"funder":7,"programme":8,"title":269,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":270},"cordis-marie-skłodowska-curie-actions-award-623501","Anticancer nanoparticles from amphiphilic macromolecular produgs","Among the numerous classes of drug delivery systems, drug-loaded polymer nanoparticles have attracted much attention. Although this approach has led to numerous encouraging results and proofs of concept in vitro, important limitations still remain, which may explain the lower number of successful in vivo studies and the limited number of marketed nanomedicines.In this view, the current project aims at developing an innovative and versatile nanoparticulate platform to prepare well-defined amphiph",{"id":272,"funder":7,"programme":8,"title":273,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":274},"cordis-marie-skłodowska-curie-actions-award-329389","3D tissue-engineered model of bone adaptation","For the development of advanced therapeutics, preventive or even cures of osteoporosis, there is a need to understand the cellular and molecular mechanisms of bone physiology. Screening and evaluation of drug effects in a reproducible controlled and dynamic 3D cell culture system would facilitate the transferability of the results from pre-clinical to clinical stage and be of high benefit for the pharmaceutical industry. Understanding tissue development in general and during regeneration and com",{"id":276,"funder":7,"programme":8,"title":277,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":278},"cordis-marie-skłodowska-curie-actions-award-627197","Influence of the protein sequence and structure on the glycan micro-heterogeneity","N-glycosylation consists in the addition of a glycan precursor onto a nascent protein in the endoplasmic reticulum. This glycan is then trimmed and matured in the Golgi by addition of various sugars motifs, leading to a large heterogeneity of glycans structures, from site to site or on the same glycosylation site. Until now the underlying causes of this micro-heterogeneity have not clearly been identified and the influence of the sugar-nucleotides pool and the glycosyltransferases present in the",{"id":280,"funder":7,"programme":8,"title":281,"piName":10,"institution":152,"country":59,"year":13,"amount":10,"abstract":282},"cordis-marie-skłodowska-curie-actions-award-624137","Investigations into Martian Volatiles","The aim of this research is to determine how the volatile element content of the martian interior, surface and atmosphere changed over geological time. This aim will be achieved via cutting-edge sub-microscopic mineralogical analyses (via transmission electron microscopy (TEM)), as well as ambitious measurements of the hydrogen isotope content and abundance of water, chlorine and fluorine in hydrous phases within martian meteorites of differing ages (via secondary ion mass spectrometry (SIMS)). ",{"id":284,"funder":7,"programme":8,"title":285,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":286},"cordis-marie-skłodowska-curie-actions-award-626934","Integrative strategy for the development of urinary bladder analogs","The current treatment of bladder defects is often associated with high site morbidity and patient discomfort. The therapeutic standard methods, involve the use of materials with low biological performance and lack in replicating the bladder’s anatomical structure. Regenerative Bladder Therapy (ReBTx) aims in addressing the reconstruction of the bladder by using an innovative bottom-up approach, to recreate the physiology of the bladder tissue. In a first stage, a 3D network based on a functional",{"id":288,"funder":7,"programme":8,"title":289,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":290},"cordis-marie-skłodowska-curie-actions-award-624767","Formation of a giant tungsten deposit: Metal sources and fluid evolution at Panasqueira, Portugal","Tungsten is a strategic resource crucial to a wide range of industries due to its unique physical properties, especially for the production of alloys and carbides. World tungsten supply is currently somewhat volatile owing to the market domination by a single nation (China), as well as recently imposed export quotas that contribute to market instability. The disappearance of EU tungsten would result in full dependence of several critical industries on imports from abroad. In this context, unders",{"id":292,"funder":7,"programme":8,"title":293,"piName":10,"institution":106,"country":107,"year":13,"amount":10,"abstract":294},"cordis-marie-skłodowska-curie-actions-award-622909","The relationship between the intestinal mucosal barrier and gut microbiota in metabolic diseases","Obesity is a world-wide epidemic and currently about 350 million people suffer from diabetes, resulting in more than 3 million deaths per year. While the gut microbiota has been identified as a contributing factor to obesity and insulin resistance in mice and humans, the underlying disease-causing mechanisms are yet to be defined. The aim of this proposal is to investigate the interactions between the gut microbiota and the intestinal mucosal barrier in metabolic disease.The human intestine is c",{"id":296,"funder":7,"programme":8,"title":297,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":298},"cordis-marie-skłodowska-curie-actions-award-627521","2LoopAccuracy4LHC","The experimental program at the Large Hadron Collider (LHC) at CERN has been very successful, leading to the discovery of a Higgs-like boson in 2012. However, the LHC experiments have so far not uncovered direct signals of new physics beyond that of the Standard Model. One may therefore anticipate an increased focus on precision measurements during the second run of the LHC, scheduled to start early 2015. This raises an acute need for increased theoretical precision in order to observe signals o",{"id":300,"funder":7,"programme":8,"title":301,"piName":10,"institution":169,"country":170,"year":13,"amount":10,"abstract":302},"cordis-marie-skłodowska-curie-actions-award-628361","Understanding the Micro-Environments of Diazotrophs and their Associated Activities in Rice","Rice (Oryza sativa L.) is one of the world’s most important crop plants. The production is strongly limited by nitrogen (N), which is typically supplied by industrial fertilizers that are costly and hazardous to the environment. Biological nitrogen fixation (BNF) through N2 fixing Bacteria and Archaea (diazotrophs) can alleviate the N-shortage in rice cultivation and was estimated to account for up to 25% of the total N-demand of the plants. However, our knowledge on N2 fixation related processe",{"id":304,"funder":7,"programme":8,"title":305,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":306},"cordis-marie-skłodowska-curie-actions-award-627767","Development of solid state NMR methods at 100 kHz magic angle spinning frequency for the study of internal protein dynamics and the application to membrane proteins","This proposal concerns the development of new solid-state NMR methods using proton detection under Magic Angle Spinning (MAS) with frequencies up to 100 kHz. The 100 kHz MAS probe head is a prototype and will allow significant gains in sensitivity by scaling down the 1H-1H dipolar coupling interaction and resulting in narrow proton line width down to 10-20 Hz. Small quantities of protein samples in the range of 0.3 to 0.5 mg allow a signal-to noise ratio that exceeds that of tens of mg in a bigg",{"id":308,"funder":7,"programme":8,"title":309,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":310},"cordis-marie-skłodowska-curie-actions-award-629995","Assessing suppression of methanogenesis in wetlands by electron accepting and polyphenolic moieties in natural organic matter","Wetlands store between 15 and 30% of the global soil carbon pool as dissolved and particulate organic matter (DOM and POM). Wetlands are also the largest natural source of atmospheric methane (CH4) and given the high warming potential of CH4, formation and loss processes of CH4 in wetlands have received considerable research interest. Yet, our understanding of methanogenesis in wetlands is incomplete.  Recent studies have implicated DOM and POM in two processes that suppress methanogenesis in we",{"id":312,"funder":7,"programme":8,"title":313,"piName":10,"institution":197,"country":184,"year":13,"amount":10,"abstract":314},"cordis-marie-skłodowska-curie-actions-award-623379","MULTIFUNCTIONAL SELF HEALING ELASTOMERS","The aim of MUSHE is to develop, for the first time, Natural Rubber compounds with self healing properties, following the intrinsic self healing approach based on reversible bonding and by the inclusion of conductive nanoparticles. In this sense, both mechanical and electrical functionalities can be restored. Special attention will be paid to the overall molecular dynamics of these materials, which can be monitored due to the nanosized conductive fillers. It is believed that a systematic research",{"id":316,"funder":7,"programme":8,"title":317,"piName":10,"institution":197,"country":184,"year":13,"amount":10,"abstract":318},"cordis-marie-skłodowska-curie-actions-award-624158","The modulation of vestibular reflexes during self-generated head-neck movements","Stable head posture is something most people take for granted, and is essential to perform daily activities such as balancing, navigating and moving. Neck muscles generate head motion to establish a stable reference frame for the visual and vestibular (i.e. balance organ) systems, allowing the rest of our body to engage in other motor behaviours. The vestibular system provides information regarding head motion in space, and is particularly important for neck muscle control. However, for people s",{"id":320,"funder":7,"programme":8,"title":321,"piName":10,"institution":322,"country":59,"year":13,"amount":10,"abstract":323},"cordis-marie-skłodowska-curie-actions-award-623394","The transfer of connected speech behaviours: external sandhi and glottalization in English-accented German","QUEEN MARGARET UNIVERSITY, EDINBURGH","The aims of the project are to analyze:1) the extent and nature of external sandhi and of glottalization of word-initial vowels in English-accented German as compared to native English productions, in relationship to prosodic boundaries and adjacent segments,2) the influence of external sandhi and of glottalization on word recognition by English and German listeners,3) the influence of external sandhi and of glottalization on the perception of phrase boundaries by English and German listeners.Ex",{"id":325,"funder":7,"programme":8,"title":326,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":327},"cordis-marie-skłodowska-curie-actions-award-624280","Fundamental investigations of high-resolution LA-ICPMS: Fast Imaging – Resolution, Sensitivity, and Time (FIRST)","Laser ablation–inductively coupled plasma mass spectrometry (LA–ICPMS) is a robust, sensitive, and wide-dynamic-range micro-analytical technique for the spatially resolved determination of elemental composition. In LA–ICPMS, a pulsed laser beam removes (ablates) minute quantities of solid sample, which are transferred online to an ICPMS for elemental and\u002For isotopic analysis. When combined with precise sample positioning, LA–ICPMS can generate two- or even three-dimensional maps of element-abund",{"id":329,"funder":7,"programme":8,"title":330,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":331},"cordis-marie-skłodowska-curie-actions-award-625913","Synthetic biology approach for the design of new-to-nature peptide-based antibiotic molecules","The rise of pathogenic bacteria that are resistant against a variety of antibiotic treatment emphasizes the need for novel active molecules. One promising novel class of active molecules is genetically encoded and ribosomally synthesized peptides, as they offer the potential to employ directed evolution approaches across a huge sequence space directly on an active substance in order to engineer novel activities and thus introduce a novel engineering principle into antibiotic development. However",{"id":333,"funder":7,"programme":8,"title":334,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":335},"cordis-marie-skłodowska-curie-actions-award-624431","Functional Imaging and Robotics for Sensorimotor Transformation","This proposed research addresses the question of how the brain transforms somatosensory information from the hand into motor commands to control the hand during tasks such as object manipulation and dexterous finger movements. Understanding the sensorimotor transformations performed by the brain to control upper limb movement is fundamental for a variety of fields, including motor development, athletic and artistic performance, sensorimotor rehabilitation, assistive technology and humanoid robot",{"id":337,"funder":7,"programme":8,"title":338,"piName":10,"institution":339,"country":28,"year":13,"amount":10,"abstract":340},"cordis-marie-skłodowska-curie-actions-award-625528","Chemical Crosstalk: targets of interkingdom signals at the host-pathogen interface","TECHNISCHE UNIVERSITAET MUENCHEN","The emergence of antibiotic resistance in bacteria, coupled with the rise in hospital-acquired infections, is a key problem for global health. There is an urgent need to discover antibiotics with novel modes of action to tackle multi-drug resistant strains and to complement current therapies. To this end, a better understanding of microbial virulence and the complexities operating at the host-pathogen interface is needed. This project aims to develop and apply novel chemical tools to understand ",{"id":342,"funder":7,"programme":8,"title":343,"piName":10,"institution":197,"country":184,"year":13,"amount":10,"abstract":344},"cordis-marie-skłodowska-curie-actions-award-327008","Enhancing Renewable Energy Socio-technical Systems in Coastal Areas","Renewable energy (RE) is nowadays promoted by European policy as key for energy security and as one response to climate change. Adoption of the EU renewable energy targets, demands a multidisciplinary approach and a closer nexus between science and local realities. In addition, local particularities in coastal areas require differentiated ways of management. This project will  a) assess the positioning of RE as a socio-technical “system” in 20 coastal European areas, b) identify specific design ",{"id":346,"funder":7,"programme":8,"title":347,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":348},"cordis-marie-skłodowska-curie-actions-award-623126","FGF-regulated miRNAs and their roles in skin inflammation and cancer","Skin cancers are the most common types of cancer in the caucasian population, and their incidence has reached epidemic proportions. In addition to skin cancer, inflammatory skin diseases are also extremely common. For the development of novel therapies for skin diseases it is essential to unravel the mechanisms that regulate skin homeostasis and pathological alterations. Recently, the host laboratory made the surprising observation that fibroblast growth factor receptor (FGFR) signalling has a t",{"id":350,"funder":7,"programme":8,"title":351,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":352},"cordis-marie-skłodowska-curie-actions-award-330024","Exploring Nuclear Localization and Functions of Arabidopsis AGO1","Plants and animals use small (s)RNA to control many developmental and physiological processes. sRNAs associate with ARGONAUTE (AGO) proteins as part of RNA-induced-silencing-complexes (RISC) to regulate gene expression at the transcriptional or post-transcriptional levels. The major effector of post-transcriptional gene silencing (PTGS) in Arabidopsis thaliana, AGO1, has been mainly implicated in cytoplasmic processes including cleavage (or ’slicing’) and translational repression of sRNA target ",{"id":354,"funder":7,"programme":8,"title":355,"piName":10,"institution":356,"country":184,"year":13,"amount":10,"abstract":357},"cordis-marie-skłodowska-curie-actions-award-623967","Sorting out host recognition of fungal infection","UNIVERSITEIT UTRECHT","The fungus Candida albicans is a common cause of human infection with serious morbidity, but the organism is also a commensal yeast that is part of the normal gut microbiota. It is becoming increasingly clear that the composition of the microbiome plays an important role in health and disease. For instance, recently it was shown that commensal fungi in the gut can contribute to the severity of colitis (inflammation of the gut). Immune recognition of C. albicans is mediated by Pattern Recognition",{"id":359,"funder":7,"programme":8,"title":360,"piName":10,"institution":356,"country":184,"year":13,"amount":10,"abstract":361},"cordis-marie-skłodowska-curie-actions-award-329183","Evaluation of mantle rheology in exhumed strike-slip faults","Crustal deformation, and associated seismic hazards, along active strike-slip faults are likely to be highly dependent on broad shear zones that occur within the uppermost mantle. The zones of localized mantle flow are physically continuous with crustal faults, and may control the bulk rheology of these systems. The main goal of this proposal is to characterize the rheological properties of naturally deformed mantle rocks and to provide insights into the control of mantle processes on deformatio",{"id":363,"funder":7,"programme":8,"title":364,"piName":10,"institution":356,"country":184,"year":13,"amount":10,"abstract":365},"cordis-marie-skłodowska-curie-actions-award-326425","The role of dynamic microtubule in the structure and function of dendritic spines","Synaptic connections within the adult brain are not fixed and stable but remarkably flexible. This reorganisation of synaptic connectivity is a basic principle of neuronal plasticity and believed to represent the cellular basis for learning and memory function. Dendritic spines form the dynamic postsynaptic component of most excitatory synapses in the brain. Recent studies from the host laboratory revealed the invasion of microtubules (MT) into dendritic spines. Several lines of evidence indicat",{"id":367,"funder":7,"programme":8,"title":368,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":369},"cordis-marie-skłodowska-curie-actions-award-623826","Mechanisms and parameters controlling cell-to-cell and long-distance movement of plant small RNAs","Basic processes within individual cells are integrated as part of the development and function of entire multicellular organisms. How this global coordination is achieved is a central question in biology. Plants use silencing small (s)RNA to control physiological and defensive processes at both the cellular and organismal levels by trafficking sRNAs from cell-to-cell through plasmodesmata and over long distances through the phloem. However, the parameters and mechanisms controlling the movement ",{"id":371,"funder":7,"programme":8,"title":372,"piName":10,"institution":157,"country":158,"year":13,"amount":210,"abstract":373},"cordis-marie-skłodowska-curie-actions-award-329018","A general law describing the diffusion of membrane proteins in vivo based on single molecule tracking of membrane proteins in Escherichia coli","The ultimate goal of cell biology is to understand how proteins function in real cells and to understand their regulatory mechanisms. To achieve this goal one needs to analyze molecules in their cellular environment and not under idealized test tube conditions. A major difference between in vivo and in vitro conditions is the crowdedness (and associated molecular complexity) of the cytoplasm and biological membranes. As a consequence diffusion in this environment is significantly slower.  To mak",{"id":375,"funder":7,"programme":8,"title":376,"piName":10,"institution":241,"country":65,"year":13,"amount":10,"abstract":377},"cordis-marie-skłodowska-curie-actions-award-302255","Stochastic Model Predictive Control, Energy Efficient Building Control, Smart Grid","Energy efficient building control can have a major impact on reducing the overall energy consumption since a large part of today's energy is consumedin buildings. The use of model predictive control (MPC) together with weather and occupancy predictions is a promising approach to realize significantenergy savings.The control of power grids is of major concern due to the increasing number of renewable energy sources which introduce additional variability. This can bemitigated against by making use",{"id":379,"funder":7,"programme":8,"title":380,"piName":10,"institution":356,"country":184,"year":13,"amount":10,"abstract":381},"cordis-marie-skłodowska-curie-actions-award-625788","HOW HUMANS ENCODE, REPRESENT AND USE BASIC SPATIAL INFORMATION IN PERCEPTION AND ACTION: BEHAVIORAL AND NEURAL EVIDENCE","The two years Fellowship project proposes a systematic investigation of the relationship between two basic processes of spatial cognition: egocentric and allocentric frames of reference and categorical and coordinate spatial relations. In particular, the project aims at: (i) clarifying the neural bases of the relationships between egocentric and allocentric frames and categorical and coordinate spatial coding; (ii) verifying behaviorally and with neuroimaging techniques the influence of the resp",{"id":383,"funder":7,"programme":8,"title":384,"piName":10,"institution":183,"country":184,"year":13,"amount":10,"abstract":385},"cordis-marie-skłodowska-curie-actions-award-624080","Enhancing cognitive flexibility in autism","The proposed project seeks to apply theoretical knowledge and insights from the research field on cognitive training and develop interventions that target flexible behaviour in autism. While empirical evidence for success of cognitive training is provided by improvement of skills within a certain task context, this project aims to determine which training regimens would target underlying mechanisms and enable the transfer of trained skills to other tasks, as well as to everyday behaviour. The pr",{"id":387,"funder":7,"programme":8,"title":388,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":390},"cordis-marie-skłodowska-curie-actions-award-331291","Single-cell phylogenomic exploration of archaeal dark matter","UPPSALA UNIVERSITET","While the archaeal domain of life was discovered more than 30 years ago, the biology of archaeal organisms remains to be relatively obscure, especially when compared to that of bacterial and eukaryotic life. Yet, despite the limited knowledge regarding their lifestyle and ecological relevance, evidence is mounting that certain archaea play key roles in global nitrogen and carbon cycles. In addition, archaea share a common branch in the tree of life with the eukaryotes, and have most likely playe",{"id":392,"funder":7,"programme":8,"title":393,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":394},"cordis-marie-skłodowska-curie-actions-award-626664","The Legitimacy of Mutual Recognition as a Regulatory Strategy for the Policy Area of Civil Justice in the EU","The research will focus on the principle of mutual recognition and the therewith presumed mutual trust between courts in the policy area of EU civil justice. The principle of mutual recognition, held to be the cornerstone of civil justice, has been transposed from its traditional Internal Market context to this novel policy arena. This transposition raises the question of how the economic and other goals of free movement can be reconciled with due process and access to justice. The research will",{"id":396,"funder":7,"programme":8,"title":397,"piName":10,"institution":398,"country":39,"year":13,"amount":10,"abstract":399},"cordis-marie-skłodowska-curie-actions-award-626794","high-throughput screening for high-grade glioma","UNIVERSITE D'AIX MARSEILLE","Glioblastoma is the most common and most malignant form of primary brain tumour. It affects both children and adults and remains virtually incurable. As a result, it is a leading cause of cancer-related deaths and more effective therapeutic strategies are urgently needed. Herein, I propose to use an innovative methodology combining high-throughput drug screening, pathway analysis and functional genomics to simultaneously develop new treatment modalities and identify novel therapeutic targets \u002F b",{"id":401,"funder":7,"programme":8,"title":402,"piName":10,"institution":403,"country":12,"year":13,"amount":10,"abstract":404},"cordis-marie-skłodowska-curie-actions-award-630095","Archaeology of Commons: cultural Heritage and Material Evidence of a Disappearing Europe","UNIVERSIDAD DEL PAIS VASCO\u002F EUSKAL HERRIKO UNIBERTSITATEA","The main goal of the project is to attain the intimate social dimension at the base of the common lands management in the context of South Europe Mountain regions, by means of historical and archaeological analysis.The existence of common lands, the complexity of their different uses and the permanence of common rights on lands were crucial in shaping rural landscapes, so they are nowadays protected as natural heritage (Natural parks, Sites of Communitarian Interest). However, the historical org",{"id":406,"funder":7,"programme":8,"title":407,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":408},"cordis-marie-skłodowska-curie-actions-award-625742","Multiple levels of selection in Fungi","This project aims to restart a research career for the fellow, allowing her to be trained to up-to-date methods in experimental work, genomic tools and data-analysis, capitalizing on her former experience in evolutionary biology. This renewed experience in research is aiming to allow the fellow to move from a current full-time teaching position to research positions.The research context of the proposal is the interaction between selection levels, in connexion with the broader issue of the emerge",{"id":410,"funder":7,"programme":8,"title":411,"piName":10,"institution":398,"country":39,"year":13,"amount":10,"abstract":412},"cordis-marie-skłodowska-curie-actions-award-627524","Advanced web tool for Isothermel Titration Calorimetry data analysis and managent","Isothermal titration calorimetry (ITC) is a powerful biophysical method to study intermolecular interaction that has become widely used due to its technological advances. It enables the determination of all thermodynamical parameters of interaction after a single one-hour experiment. The key step of experimental data analysis is the fitting of obtained data using an appropriate binding model. Unfortunately, the limited set of models offered by manufacturers does not allow the full use of ITC for",{"id":414,"funder":7,"programme":8,"title":415,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":416},"cordis-marie-skłodowska-curie-actions-award-627569","Exploiting RESonant processes to understand CORrelations","Spectroscopy is one of the fundamental tool in condensed matter physics, materials science and nanoscience. Resonant spectroscopies, like Resonant Inelastic X-ray Scattering (RIXS) and angle resolved Resonant PhotoEmission Spectroscopy (RPES), offer invaluable information on the system under investigation, being able to probe different types of excitations, from electron-hole pairs (excitons), to spin-flip, to collective excitations, to orbital and magnetic excitations. This proposal aims at imp",{"id":418,"funder":7,"programme":8,"title":419,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":420},"cordis-marie-skłodowska-curie-actions-award-627096","Tools to aid coral reef managers in French Polynesia and other reef regions to build resilience to climate change into management and conservation planning","Assessing and reducing vulnerability to climate change is now the hallmark of many conservation programs and for coral reefs involves supporting the natural resilience of these biodiverse systems. Marine protected areas zoned for multiple use are the main tool used to support reef resilience. This project seeks to inform resilience-based coral reef management and conservation planning in French Polynesia in the first and second project phases, and in all reef regions in phase 3.  We aim to ident",{"id":422,"funder":7,"programme":8,"title":423,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":424},"cordis-marie-skłodowska-curie-actions-award-624918","Structure and Dynamics of Metal Ion Transporters using Solid-State Nuclear Magnetic Resonance at High Field and Fast Magic Angle Spinning","We propose the determination of metal transporter structures using high field and fast (>60 kHz) magic angle spinning NMR spectroscopy. Proteins provide the basis for many important biological processes. They are found as soluble protines, such as enzymes, membrane associated proteins that interact with specific locations in the cell, and transmembrane (TM) proteins that often serve as the gatekeepers of cellular compartments. Membrane proteins comprise 20 to 30 percent of all proteins, however,",{"id":426,"funder":7,"programme":8,"title":427,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":428},"cordis-marie-skłodowska-curie-actions-award-623712","Coupling Confined Optical and Mechanical Modes to a Single Quantum Dot","The project bridges the gap between two yet distinct research fields: optomechanics of deformable cavities (cavity optomechanics) and cavity quantum electrodynamics (cavity QED).  This project aims at exploring a hybrid interface between these two domains, using semiconductor nanostructures. In particular, we propose the use of a single quantum dot (QD) coupled to a pillar microcavity to study photon-phonon interactions.  It has been demonstrated that an optimized optical GaAs\u002FAlAs-based microca",{"id":430,"funder":7,"programme":8,"title":431,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":433},"cordis-marie-skłodowska-curie-actions-award-622659","Assembling molecular components for future quantum devices","THE UNIVERSITY OF MANCHESTER","The project proposed herein is based on recent results reported by Winpenny group. In those papers they have shown that can functionalise heterometallic rings, suitable to be used as qubits, for building assemblies with two components relevant to application in quantum information processing (QIP). Assemblies of increasing complexity could be made and ultimately a prototype for quantum simulator for quantum computers. The experience of Jesus Ferrando Soria makes him an ideal scientist to pursue ",{"id":435,"funder":7,"programme":8,"title":436,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":437},"cordis-marie-skłodowska-curie-actions-award-625351","NEGAtive REpresentation: Ostracism, Recall and Negative Voting as Electoral Innovations Against Extremism","In the last two decades, Europe has been witnessing a steady rise of anti-democratic trends and disappointment with politics. Faced with these challenges, contemporary democracies appear vulnerable and unable to defend themselves. This project proposes a democratic theory of ‘negative representation’ that involves the re-activation of electoral agency with the aim of producing responsible leadership. I suggest to view representation not only from the usual viewpoint as a process of selecting ‘th",{"id":439,"funder":7,"programme":8,"title":440,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":441},"cordis-marie-skłodowska-curie-actions-award-329969","Molecular Targets of Uranium in some Aquatic Organisms","Uranium is an important element, massively used in military and civil industry. It is a toxic element and the understanding of the mechanisms of its metabolism, homeostasis and toxicity are of paramount importance. The project aims at the development of a series of novel analytical methods able to identify and quantify the species being products of interaction of uranium with the proteome and metabolome of some aquatic organisms. The organisms include microalgae Fragilariopsis cylindrus and Kare",{"id":443,"funder":7,"programme":8,"title":444,"piName":10,"institution":403,"country":12,"year":13,"amount":10,"abstract":445},"cordis-marie-skłodowska-curie-actions-award-628876","Photophysics of Fluorescent Proteins","Fluorescent fusion tags have revolutionized many fields in molecular biology. Since the first applications of the Green Fluorescent Protein (GFP) extracted from the jellyfish Aequorea victoria, the photophysical properties of the protein have been improved and modified to optimize their application in various novel in vivo imaging techniques. These applications exploit, unique properties of fluorescence proteins (FPs), such as pH-sensitivity, and Förster resonant energy transfer (FRET), photoact",{"id":447,"funder":7,"programme":8,"title":448,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":449},"cordis-marie-skłodowska-curie-actions-award-625700","Gold-catalysed dehydrogenative cross-coupling of arenes","The usually inert carbon-hydrogen (C-H) bond is present in nearly all synthetic and naturally occurring organic molecules. The modification of organic compounds through the direct functionalisation of C-H bonds is however a highly challenging process due to their poor reactivity and the difficulty of discriminating between the many C-H bonds present in most molecules. Nevertheless, catalytic C-H activation has emerged as an increasingly promising strategy for simple and atom-economical cross-cou",{"id":451,"funder":7,"programme":8,"title":452,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":453},"cordis-marie-skłodowska-curie-actions-award-625555","A Reloadable Molecular Peptide Synthesizer","The sequence-specific synthesis of information-rich oligomers and polymers is achieved in nature through the operation of complex molecular machines that transcribe information from the genetic code. The most extraordinary of these ‘molecular factories’ is the ribosome, a molecular machine found in all living cells that assembles amino acids from transfer RNA (tRNA) building blocks into a peptide chain with an order defined by the sequence of the messenger RNA (mRNA) strand that it moves along. ",{"id":455,"funder":7,"programme":8,"title":456,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":457},"cordis-marie-skłodowska-curie-actions-award-624969","Animated 3D digital reconstructions of early European birds: a new window on the origin of avian flight using “state-of-the-art” techniques on exceptional fossils","The origin of avian flight is possibly the most spectacular example of an evolutionary transition and, consequently, has aroused passionate scientific debate and fired public attention. The fossil record indicates that birds emerged within theropods (a group of carnivorous dinosaurs that includes species such as Tyrannosaurus rex) in the Late Jurassic. Mesozoic birds are extremely rare. Their fossil remains are mostly known from exceptional sites such as that of Las Hoyas, in Spain. Four beautif",{"id":459,"funder":7,"programme":8,"title":460,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":461},"cordis-marie-skłodowska-curie-actions-award-627852","The Reception of Irish Literature in Italy: 1900-1950","This research project aims to investigate crucial aspects of the reception of Irish literature in Italy during the first fifty years of the twentieth century, with special attention to the politics of translation and mediation in the fascist era. Having devised a theoretical framework that combines cultural and translation studies with evidence-based historical research, I will read archival evidence in the light of recent scholarship on cultural mediation\u002Ftranslation, and discuss the strategies",{"id":463,"funder":7,"programme":8,"title":464,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":465},"cordis-marie-skłodowska-curie-actions-award-624877","Graphene Heterostructures by Self-Assembly:Top-down meets Bottom-up","One-atom thin two-dimensional nanomaterials possess unique properties different from their bulk counterparts. Initiated by the discovery of graphene, many stable one atom-thick layers such as boron nitride, molybdenum disulphide, tungsten disulphide etc., have been isolated and characterized. However, the individual properties of such 2D-atomic crystals (except graphene) were modest. The combination of isolated single atomic layers into designer structures, named as 2D-heterostrcutures, is predi",{"id":467,"funder":7,"programme":8,"title":468,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":469},"cordis-marie-skłodowska-curie-actions-award-626740","The phenomenological concept of institution: event, history, symbolic","The project aims at illustrating the specificity and fecundity of the phenomenological concept of Stiftung\u002F“institution”. Thanks to its joint reference to the taking place of an event and the opening of a new dimension of meaning, the concept of institution allows us to map out a rich and articulated field of research, the potential of which still awaits to be fully fleshed out in the literature. The project also aims at filling this gap, in particular by writing some papers and a book on the th",{"id":471,"funder":7,"programme":8,"title":472,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":473},"cordis-marie-skłodowska-curie-actions-award-625521","Shedding light on the diversity, ecology and evolution of enigmatic, uncultivated archaea using novel single cell and metagenomics approaches","The Archaea represent the Third Domain of Life and comprise a group of microorganisms that are important players in major biogeochemical cycles. Yet,  even though more than 30 years have passed since their discovery, the biology, lifestyle and diversity of the archaeal domain of life remain to be poorly understood thus far, especially when compared to that of Bacteria and eukaryotes.Recent environmental surveys have revealed the existence of a vast, uncultured archaeal diversity, and the charact",{"id":475,"funder":7,"programme":8,"title":476,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":477},"cordis-marie-skłodowska-curie-actions-award-626195","Arylation and Vinylation of Enolates: New Reactivity from the Urea Linkage","Enols and enolates are among the most versatile nucleophiles in chemistry: they react well with alkylating agents or carbonyl compounds, but their coupling with aryl or alkenyl halides is usually dependent on Pd-based catalysts for enol–aryl coupling. In this proposal we aim to develop new possibilities for enolate arylation that reveal fundamental new reactivity and will have repercussions throughout the science of synthetic planning. The method builds on some arylation reactions of urea-contai",{"id":479,"funder":7,"programme":8,"title":480,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":481},"cordis-marie-skłodowska-curie-actions-award-629418","Non-linear Optical Imaging of Myelin and Metabolism in living tissues","The overall goal of OpticMyeliMet project is to develop non-invasive multi-modal non-linear optical (NLO) methods to simultaneously probe myelin and cellular metabolism during the evolution of Multiple sclerosis (MS) pathology. The myelin sheath plays a crucial role in the vertebrate nervous system, by providing energetic support for neurons. MS is characterized by the occurrence of disruption of myelin (demyelination), as well as cellular energetic failure and neurodegeneration. Therefore the d",{"id":483,"funder":7,"programme":8,"title":484,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":485},"cordis-marie-skłodowska-curie-actions-award-329926","Statistical models for musical signal processing","This project lies in the interdisciplinary field of Music Information Retrieval (MIR). The objective of the project is the development of innovative technologies for enabling access to the immense amount of audio music collections that are available on the Web. Bringing together efforts from speech and signal processing, statistical modeling, musicology and machine learning, we seek to build efficient models that allow the automatic extraction of musical content information from audio signals. W",{"id":487,"funder":7,"programme":8,"title":488,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":489},"cordis-marie-skłodowska-curie-actions-award-625388","Multiple Scattering description of Ballistic Electron Emission Miscroscope for materials used in spin injection","Spintronics is now a major challenge at the international level with the prospect of manipulating, storing and transporting the electron spin in semiconductors. This will lead to a whole new family of much faster devices, working at low power, including programmable spin transistors. It has been demonstrated that the efficiency of spin injection is strongly dependent on the structure of the interface between the layers involved, and therefore it is essential to be able to characterize the struct",{"id":491,"funder":7,"programme":8,"title":492,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":493},"cordis-marie-skłodowska-curie-actions-award-622738","The active pupil: The role of pupil size in active vision","The pupil is a volatile surface. It shrinks when we step out into the sun, and expands when we get aroused or exert mental or physical effort. These basic pupillary responses have been recognized at least since Roman times, and have been the focus of systematic investigation since the 18th century. Currently, pupil-size measurement, or pupillometry, is an established tool for diagnosing visual defects, and is widely used as a marker of arousal or effort in psychological experiments and clinical ",{"id":495,"funder":7,"programme":8,"title":496,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":497},"cordis-marie-skłodowska-curie-actions-award-630076","Iconicity and ecology of languages: new insight","In the present project, we propose a pioneer research that will provide new insights into human language ecology and evolution by exploring three rarely studied natural traditional oral practices with a multidisciplinary methodology. These are alternative speech forms that always rely on a spoken language and that consist of mapping voiced speech signals into very different types of sounds, such as whistling, instrumental music and animal calls. These speech transformations are respectively call",{"id":499,"funder":7,"programme":8,"title":500,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":501},"cordis-marie-skłodowska-curie-actions-award-623742","Early Acquisition of Argument Structure","The planned research will investigate the early acquisition of argument structure, a crucial example of syntax-semantics linking, in Estonian and cross-linguistic comparison. The project investigates 2 to 5-year-old children’s ability to use information from different cues signalling argument structure, namely word order, case marking, and the discourse context. The rich inflectional system and flexible word order of Estonian provide a sharp contrast to English, on which most studies of syntacti",{"id":503,"funder":7,"programme":8,"title":504,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":505},"cordis-marie-skłodowska-curie-actions-award-628138","Strong interactions of periodically-driven trapped ions, cold atoms and molecules","In the proposed project we will develop a theoretical framework for analyzing periodically-driven phases of ultracold matter in a nonperturbative way, focusing on a general understanding of the structure of solution sets in parameter space. This will enable us to present original ideas for reaching new regimes of quantum many-body physics.Cold, trapped, strongly interacting ionic and neutral atoms and molecules, subject to periodic electromagnetic fields, will be studied using novel analytical a",{"id":507,"funder":7,"programme":8,"title":508,"piName":10,"institution":509,"country":510,"year":13,"amount":10,"abstract":511},"cordis-marie-skłodowska-curie-actions-award-628326","Fungal conservation genetics: species traits and dispersal","UNIVERSITETET I OSLO","NO","Wood-decay fungi are essential for the functioning of forest ecosystems: they drive wood decomposition and soil formation in forests. They provide habitat for many other organisms and enable the regeneration of forests throughout the world. But many wood-decay fungi are threatened by forest management, and up to 42% of the species are in national Red Lists. Their occurrence in fragmented forest landscape is limited by ecological, evolution and dispersal traits. In order to address mechanisms res",{"id":513,"funder":7,"programme":8,"title":514,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":515},"cordis-marie-skłodowska-curie-actions-award-626190","SYSTEMS BIOLOGY APPROACH TO PREDICTING OUTCOMES OF LUNG CANCER THERAPIES AND STRATEGIES TO OVERCOME DRUG RESISTANCE IN VITRO","There has been extensive research dedicated to identifying predictive biomarkers of tumor sensitivity to ligand-based therapies. Although some biomarkers have emerged, there is still no comprehensive understanding that unifies the observed tumor cell type-specific behaviors, in particular the differential responses to anti-cancer drugs.The collective realization is that no single protein measurement is predictive of therapeutic outcome. Large-scale studies focusing on multiple genetic biomarkers",{"id":517,"funder":7,"programme":8,"title":518,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":519},"cordis-marie-skłodowska-curie-actions-award-627243","New aspects of supergravity: the gravity dual of supersymmetric localization and string theory compactifications to de Sitter space","This project explores new aspects of supergravity theories in relation with string theory. It consists of two main parts, each with specific objectives. The first part studies novel structures in the AdS\u002FCFT correspondence, focusing on supergravity solutions dual to supersymmetric field theories on curved manifolds. We will construct new supersymmetric, asymptotically locally (Euclidean) Anti de Sitter supergravity solutions, and compute the holographic partition function and other relevant obse",{"id":521,"funder":7,"programme":8,"title":522,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":523},"cordis-marie-skłodowska-curie-actions-award-332393","A Panchromatic Approach to Unlocking the Transient Radio Universe","The project presented in this proposal aims to develop a rapid response system for the new generation of radio telescopes. This system will automate interactions with astronomical facilities operating over the whole range of the electromagnetic spectrum in order to quickly process their transient alerts and trigger radio follow ups. This feature will make a significant contribution to the field of time-domain radio astronomy which is facing the challenge of exploring a new area of research param",{"id":525,"funder":7,"programme":8,"title":526,"piName":10,"institution":509,"country":510,"year":13,"amount":10,"abstract":527},"cordis-marie-skłodowska-curie-actions-award-624421","Pathways, ecological and genomic consequences of genome duplication in Arabidopsis arenosa, an overlooked diploid-polyploid member of the model genus Arabidopsis","The project addresses critical gaps in our understanding of the role of genome duplication (polyploidy) in the genesis and maintenance of plant diversity. While polyploidization is widely acknowledged as a major speciation mechanism in land plants, little is still known about the performance, dynamics, and evolutionary potential of wild polyploid lineages. In my project I propose an interdisciplinary research at the interface between plant systematics, population genetics, and ecological and evo",{"id":529,"funder":7,"programme":8,"title":530,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":531},"cordis-marie-skłodowska-curie-actions-award-328546","New Catalytic C-H Activation and Decarboxylation Chemistry","We propose a wide-ranging and ambitious programme of work that looks to develop new synthetic chemistry in the areas of catalytic decarboxylation and  C-H bond activation. The discovery of new catalyst systems that can selectively manipulate unreactive C-H bonds represents a major area of research in synthetic chemistry. Whilst C-H activation is one of the most active areas of current research, it remains in its infancy with respect to regio and stereo-control, green chemistry concerns and appli",{"id":533,"funder":7,"programme":8,"title":534,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":535},"cordis-marie-skłodowska-curie-actions-award-625058","Ultrahigh resolution NMR tools for chemistry and structural biology","Solution NMR spectroscopy is among the most important techniques in natural science, particularly for structural biology and organic chemistry research. Spectral resolution and sensitivity are the key parameters controlling access to structural information at the atomic level; at present it is resolution that limits the complexity of structural problem, whether chemical or biological, that NMR can be applied to. Multidimensional NMR has allowed huge strides to be made in studies of the 3D struct",{"id":537,"funder":7,"programme":8,"title":538,"piName":10,"institution":403,"country":12,"year":13,"amount":10,"abstract":539},"cordis-marie-skłodowska-curie-actions-award-629050","Novel Amide Based Polymeric ionic Liquids: Potential Candidates for CO2 capture","Global warming is certainly an alarming environmental issue at present owing to rising CO2 level in the atmosphere that needs to be addressed instantly1. Carbon dioxide has been proven to be a greenhouse gas (GHG), which contributes to the increase in earth’s surface temperature, ocean acidity and air toxicity, and may cause adverse climate changes. Existing scenario reveals the demand to reduce CO2 emissions by capturing it prior to emission, depositing in a suitable repository and then its uti",{"id":541,"funder":7,"programme":8,"title":542,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":544},"cordis-marie-skłodowska-curie-actions-award-623553","Maize Candy-leaf mutants: a tool for the study of grass-specific cell wall biology with potential applications in renewable energy production and cereal crop pathogen protection","AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS","A modern bioeconomy needs to valorise the potential of carbon neutral resources, in particular the environmentally and socially acceptable, and economically competitive utilization of plant biomass. Most of the plant biomass consists of durable lignocellulosics what provide structural strength for the plant and are the first line of defence against invading pathogens. It is thus desirable to improve the lignocellulosic components of plants in a way that they do not perturb their function and thu",{"id":546,"funder":7,"programme":8,"title":547,"piName":10,"institution":398,"country":39,"year":13,"amount":10,"abstract":548},"cordis-marie-skłodowska-curie-actions-award-625185","Interactions between nitrogen-fixers (diazotrophs) and dissolved organic matter in the ocean","Primary production in the oceans is strongly limited by the availability of fixed nitrogen. In open ocean nutrient-impoverished areas, which make up ~50% of the global ocean surface, nitrogen is mainly provided through the process of biological atmospheric nitrogen (N2) fixation. N2 fixation is carried out by the so termed diazotrophs, marine microorganisms that may belong to the cyanobacteria, bacteria or archaea. For many years, autotrophic diazotrophs were thought to be the most abundant diaz",{"id":550,"funder":7,"programme":8,"title":551,"piName":10,"institution":552,"country":45,"year":13,"amount":10,"abstract":553},"cordis-marie-skłodowska-curie-actions-award-623386","Quantification and source apportionment of brown carbon aerosols in the high Himalayas","CONSIGLIO NAZIONALE DELLE RICERCHE","The high Himalayan glaciers that provide the water supply of large Indian rivers are significantly affected by anthropogenic climate warming. The light-absorbing aerosols participate in the Himalayan glaciers’ retreat processes not only via their contribution to climate warming, but also due to reduction of the albedo of the glaciers and weakening of the South Asian monsoon that feeds the glaciers. Several recent observational and modeling studies showed the light-absorbing organic aerosols – “b",{"id":555,"funder":7,"programme":8,"title":556,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":557},"cordis-marie-skłodowska-curie-actions-award-623456","Heisenberg's uncertainty principle and the Foundations of Quantum Theory in the light of Quantum Information","Despite the great success of quantum theory, a clear understanding of its foundations is missing; the question of why the world follows such puzzling rules is still begging for an answer. By revolutionizing the way we perceive and manipulate information, the emergence of quantum information science has allowed recent progress in quantum foundations, and led to the development of innovative applications and technological advances, with a great impact on society.This promises even more discoveries",{"id":559,"funder":7,"programme":8,"title":560,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":561},"cordis-marie-skłodowska-curie-actions-award-622882","The Visual Front-End of Reading","This research proposal aims at deepening the understanding of one fundamental issue of human cognition – how the perceptual fluency associated with skilled word reading is learned – and in doing so will provide for the first time a comprehensive learned neurocomputational account of printed word perception. The issue is of extreme general interest because it regards the establishment of one ontogenetic humanity achievement, symbolic language communication, on the top of cortical structures evolv",{"id":563,"funder":7,"programme":8,"title":564,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":565},"cordis-marie-skłodowska-curie-actions-award-332350","Probing cosmic accelerators through atmospheric calibration and precision very-high-energy gamma-ray spectroscopy","Very-high-energy (VHE; 50 GeV \u003C E \u003C 100 TeV) gamma-ray telescopes observe cosmic particle accelerators, probing fundamental acceleration processes at energies far beyond those achievable at terrestrial accelerators and in extreme environments such as supernova remnants, pulsars, pulsar winds, and the Galactic Center.  The upgraded H.E.S.S.-II telescope array saw first light in July 2012 and represents the cutting edge of the imaging atmospheric Cherenkov technique that enables observations of VH",{"id":567,"funder":7,"programme":8,"title":568,"piName":10,"institution":398,"country":39,"year":13,"amount":10,"abstract":569},"cordis-marie-skłodowska-curie-actions-award-328416","Mediterranean overturning circulation","The air-sea interactions and the interior mixing are key processes of the global oceanic meridional overturning circulation and in setting the properties (temperature, salinity, chemical concentration) of water masses. Such processes are only crudely parameterized in global ocean models and coupled climate models due to their relatively coarse resolution and the lack of physical understanding of the mixing processes. Due to its unique geometry; to its relatively small size and to its similaritie",{"id":571,"funder":7,"programme":8,"title":572,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":573},"cordis-marie-skłodowska-curie-actions-award-628428","Towards a comprehensive characterisation of the Neolithic societies through their graphic expressions: cultural identities and contacts in the Western Mediterranean","This project focus on one of the more exciting cultural, economic and social transformation process: the Neolitisation and expansion of  Neolithic societies in the Western Mediterranean (VI.mill .cal BC-III.mill cal. BC).The main goal of this project is to provide a comprehensive characterization of  this cultural process in the Iberian Peninsula as well as of the cultural relationships between this territory and the European Western Mediterranean regions through their graphic expressions (rock ",{"id":575,"funder":7,"programme":8,"title":576,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":577},"cordis-marie-skłodowska-curie-actions-award-622735","Research of new marine inhibitors targeted against desease-relevant proteins kinases","Project OCEANCHArCoT – OCEAN CHemodiversity Against Cell cycle Targets.Protein Kinases (PKs) are involved in various human pathologies such as cancer, neurodegenerative diseases or can be targeted to alter the life cycle of various parasites such as those responsible neglected parasitic diseases such as leishmaniasis and malaria. There are no physiological events not involving significant changes in protein phosphorylation. Therefore, PKs constitute currently the first class of targets used by p",{"id":579,"funder":7,"programme":8,"title":580,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":581},"cordis-marie-skłodowska-curie-actions-award-622906","Ionic Liquids as innovative organic phase for solvent extraction and separation of lanthanoids: a comparative study of conventional and synergistic systems","A significant interest has been paid to Ionic Liquids in the last years as innovative and perspective medium for solvent extraction. ILs, a new class of solvents with unusual solvating properties are one of the most interesting and rapidly developing areas of modern chemistry, technology and engineering. They have already proved to be efficient media for the extraction of a large variety of metals. Therefore, to improve the extraction and separation of lanthanoids, the development of solvent ext",{"id":583,"funder":7,"programme":8,"title":584,"piName":10,"institution":585,"country":59,"year":13,"amount":10,"abstract":586},"cordis-marie-skłodowska-curie-actions-award-623409","PROTECTED AREAS AND THE EXPANSION OF NEOLIBERAL CAPITALISM IN EUROPE","THE UNIVERSITY OF SHEFFIELD","Central to the constitution of current ecological crises are modernist environmental views that separate nature from society, culture and civilisation and which make possible large-scale exploitation and despoliation of natural resources. In recent decades, the critical study of conservation conflicts have contended that, despite promoting new environmental attitudes, most conservation initiatives have failed to query the nature-society separation that underlies ecologically depredatory initiati",{"id":588,"funder":7,"programme":8,"title":589,"piName":10,"institution":590,"country":96,"year":13,"amount":10,"abstract":591},"cordis-marie-skłodowska-curie-actions-award-624680","Marine Aerosol NUcleations","UNIVERSITY OF GALWAY","The topic of this proposal is the natural marine aerosol, which is of paramount importance at the global scale and influences the Earth’s radiative budget and the biogeochemical cycles. New particle formation dominates the atmospheric aerosol number budgets and most of these particles are formed by nucleation of marine biogenic vapours. MANU (Marine Aerosol NUcleations) aims to directly identify the spontaneous creation of new nanometer-sized particles in the open ocean marine atmosphere and to ",{"id":593,"funder":7,"programme":8,"title":594,"piName":10,"institution":403,"country":12,"year":13,"amount":10,"abstract":595},"cordis-marie-skłodowska-curie-actions-award-622934","Optical charge transfer processes in early stages of photosynthesis from first-principle computational techniques","Optically exited charge-transfer states play a crucial role in the early stages of photosynthesis  but are notoriously difficult to describe efficiently with first-principles computational techniques. This difficulty not only limits the current understanding of the detailed atomistic processes in photosynthesis but is also an obstacle in simulating novel designs of photovoltaic materials that are based on organic absorbers. Current first-principles techniques for electronic excitations suffer ei",{"id":597,"funder":7,"programme":8,"title":598,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":599},"cordis-marie-skłodowska-curie-actions-award-629604","Post-glacial recolonisation and Holocene anthropization impact on populations of shrews and hedgehogs from Western Europe inferred from zooarchaeology, historical biogeography and ecological modeling","At the end of last glaciation, ca. 15 000 cal. yrs ago, small mammals which had receded in the glacial refuges of southern Europe during the last pleniglacial started to spread again northward. This movement, which lasted several millenia -and which is still operating in a few cases- has been investigated through a number of phylogeographic works relying chiefly on molecular grounds so far. Comparatively few has been done on the basis of actual zooarchaeological data, especially for insectivores",{"id":601,"funder":7,"programme":8,"title":602,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":603},"cordis-marie-skłodowska-curie-actions-award-623845","LANGUAGE AND JOINT ACTION","A conversation is a clear example of joint activity. However, little is known how the more basic sensori-motor processes underlying joint action apply to the complex interwoven between language production and comprehension during communication. The present project aims to contribute to our understanding of language as a joint action by exploring how the two fundamental processes that contribute to the success of any joint action, namely prediction and monitoring, are engaged during verbal commun",{"id":605,"funder":7,"programme":8,"title":606,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":607},"cordis-marie-skłodowska-curie-actions-award-624370","Nanomedicine and Hadrontherapy","Cancer is one of the most feared diseases. Radiotherapy is commonly used in about 50% of all cancer patients. Although the radiotherapeutic protocols have been improved significantly, only a limited number of patients are entirely cured and severe side effects are often induced. Hadrontherapy and protontherapy are approaches superior to conventional photon radiotherapy because of the maximal energy they deposit at the end of the track (the Bragg peak) and the absence of damage induced behind the",{"id":609,"funder":7,"programme":8,"title":610,"piName":10,"institution":611,"country":107,"year":13,"amount":10,"abstract":612},"cordis-marie-skłodowska-curie-actions-award-624054","Charting the holographic quantum landscape, and consequences on charge transport at strong coupling","STOCKHOLMS UNIVERSITET","This proposal aims at elucidating the properties of charge transport at strong coupling, when no quasiparticle description is valid. We will employ techniques from gauge\u002Fgravity duality, which comes from String Theory and High Energy physics and maps a strongly-coupled field theory with a UV conformal fixed point to an asymptotically Anti-de Sitter gravitational spacetime described by Einstein’s equations.  Possible applications can be found in strongly-coupled Condensed Matter systems.Scaling p",{"id":614,"funder":7,"programme":8,"title":615,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":616},"cordis-marie-skłodowska-curie-actions-award-623255","SYNTHETIC NITRENE CHEMISTRY: NEW REACTIONS AND APPLICATION","The paramount importance of nitrogen in life and material sciences makes the search for new C-N bond forming reactions a topic of utmost interest that lies at the heart of organic synthesis and medicinal chemistry. This is a highly competitive domain, and, with the advent of organometallic catalysis, there have been numerous breakthroughs. This proposal resides at the forefront of this field, with the aim to enhance the synthetic understanding of nitrenes and to unveil new methods for the synthe",{"id":618,"funder":7,"programme":8,"title":619,"piName":10,"institution":620,"country":621,"year":13,"amount":10,"abstract":622},"cordis-marie-skłodowska-curie-actions-award-628892","Collateral effects of language in use","HELSINGIN YLIOPISTO","FI","The overall research objective of the proposed project is to investigate to what extent the language we speak influence our ability to act in the world. Building on the theoretical and methodological foundations of disciplines such as Conversation Analysis, Linguistic Anthropology and Interactional Linguistic, and taking as its point of departure the idea that language is a resource for accomplishing social action, the project will conduct an empirically based study to determine the range of lin",{"id":624,"funder":7,"programme":8,"title":625,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":626},"cordis-marie-skłodowska-curie-actions-award-627696","Stress, Prefrontal function and Cognition: Role of the Glucocorticoid Receptor","Cognitive deficits are hallmark features of a variety of psychiatric diseases. While body of evidences pointed to the prefrontal cortex (PFC) as a key structure for cognition, recent studies further suggested that abnormalities in the interaction between inhibitory interneurons and glutamatergic pyramidal cells within PFC microcircuit could be involved in the pathogenesis of cognitive deficits in psychiatric disorders. Thus, intensive effort has been made to understand the mechanisms underlying ",{"id":628,"funder":7,"programme":8,"title":629,"piName":10,"institution":630,"country":631,"year":13,"amount":10,"abstract":632},"cordis-marie-skłodowska-curie-actions-award-627195","Black holes altering galaxy evolution: how to find them?","ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON","EL","A major challenge in our understanding of the Universe is that cosmological simulations of galaxy formation and evolution fail to reproduce the mass distribution of present-day galaxies, producing more massive galaxies than those observed. Black holes are claimed capable of solving the problem by accelerating gas and expelling it out of galaxies through radiation pressure, plasma jets, or accretion-disk winds. Recent observations confirmed the existence of outflows carrying more molecular gas th",{"id":634,"funder":7,"programme":8,"title":635,"piName":10,"institution":620,"country":621,"year":13,"amount":10,"abstract":636},"cordis-marie-skłodowska-curie-actions-award-628150","HPeV3 structural and functional studies","Human parechovirus 3 (HPeV3) belongs to the genus Parechovirus within the large and growing family of Picornaviridae. Currently, the Picornaviridae family contains 37 species grouped into 17 genera. All picornaviruses are small icosahedrally-symmetric non-enveloped viruses that possess single-stranded, positive-sense RNA genomes. Picornaviruses, including parechoviruses, contain significant human pathogens that can cause a wide range of disease symptoms. Parechoviruses mainly cause asymptomatic ",{"id":638,"funder":7,"programme":8,"title":639,"piName":10,"institution":640,"country":45,"year":13,"amount":10,"abstract":641},"cordis-marie-skłodowska-curie-actions-award-624433","European emigration governance - emigration and diaspora policies and discourses in the post-crisis era","EUROPEAN UNIVERSITY INSTITUTE","The project breaks new ground in the study of migration governance by looking at the so-called immigration countries from the perspective of emigration governance. The main underlying theme of this research is that emigration and immigration are two sides of the same coin and thus European migration governance should be approached from two angles to understand its full dimension.European Union is in fact still a region of emigration, with majority of flows staying within its boundaries, but impo",{"id":643,"funder":7,"programme":8,"title":644,"piName":10,"institution":640,"country":45,"year":13,"amount":10,"abstract":645},"cordis-marie-skłodowska-curie-actions-award-628734","Distributive Effects and EU Private Law: Justificatory Practices of EU Institutions in a Constitutional, Methodological and Communicative Perspective","The project examines the role of distributive justice claims in the official discourse of EU private law. EU private law traditionally encompasses a series of Directives and Regulations enacted in order to protect consumers and employees, and the related case law of the Court of Justice of the EU. The project focuses on the use in official EU documents, such as the Commission's policy statements, impact assessment reports, preambles to EU legislative acts or judgments of the Court of Justice, of",{"id":647,"funder":7,"programme":8,"title":648,"piName":10,"institution":620,"country":621,"year":13,"amount":10,"abstract":649},"cordis-marie-skłodowska-curie-actions-award-625653","Coevolution of the Cladoniaceae and associated fungi","Cladoniaceae is one of the largest and most diverse families of lichens. It includes about 500 species. The species comprise significant components of numerous terrestrial ecosystems around the world. In addition, Cladoniaceae has proved to be an exceptionally favored host for numerous, poorly known lichenicolous fungi. Altogether 83 species of these fungi have been reported to grow on the Cladoniaceae and most are specified to live on single host taxon only. Our goal is to combine the phylogeny",{"id":651,"funder":7,"programme":8,"title":652,"piName":10,"institution":640,"country":45,"year":13,"amount":10,"abstract":653},"cordis-marie-skłodowska-curie-actions-award-326814","Tra_Med - patterns of pastoral migrations in the Mediterranean region","The proposed research addresses an important knowledge gap affecting the scientific as well as the policy making communities in the EU and its neighbours. It looks at the interface between migration dynamics and EU policies on agriculture and rural development, two domains that are raising concern amongst EU public opinion and institutions.While it is recognised that different migrant communities play nowadays an important role in agricultural activities throughout the EU, the implications of th",{"id":655,"funder":7,"programme":8,"title":656,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":657},"cordis-marie-skłodowska-curie-actions-award-622142","SUPPRESSION OF RNA DEGRADATION BY PLANT PARARETROVIRUS: HIJACKING OF DECAPPING COMPLEXES","During pathogenesis, viruses hijack the cellular machinery to access molecules and sub-cellular structures needed for infection. Viruses counteract plant defences by producing suppressor proteins. We have evidence that multifunctional viral protein—translation transactivator\u002F viroplasmin from Cauliflower mosaic virus, CaMV—could be used as a suppressor of cellular RNA turnover: the cellular accumulation of TAV inhibits cellular mRNA decay and suggests its complex formation with the decapping mac",{"id":659,"funder":7,"programme":8,"title":660,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":662},"cordis-marie-skłodowska-curie-actions-award-626116","Bacterial host cell death modulators – a genetic approach to identify anti-apoptotic factors of Chlamydia trachomatis and to explore their role during infection","INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE","Chlamydia trachomatis is a leading cause of sexually transmitted disease - with reported prevalence rates of up to 17% among asymptomatic women in Europe - and as such a frequent cause of infertility. While these bacteria have been known for more than a decade to protect infected cells from apoptosis, the lack of tools for genetic manipulation of chlamydiae significantly hampered the investigation of underlying molecular mechanisms and their role during infection. Yet, the research group of Dr. ",{"id":664,"funder":7,"programme":8,"title":665,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":666},"cordis-marie-skłodowska-curie-actions-award-627134","Mechanistic Studies on Carbon Monoxide (CO)-Induced Modulation of Mitochondrial Function in Neuroinflammation","Neuroinflammation plays a crucial role in the development and progression of neurodegenerative diseases such as Alzheimer’s or ischemic stroke. The inflammatory response is coordinated by resident cells (microglia) that upon activation produce pro-inflammatory mediators including cytokines, chemokines and reactive oxygen species. Identification of small molecules that alleviate microglia inflammation is therefore pivotal in uncovering feasible therapeutic approaches to treat brain disorders. Eme",{"id":668,"funder":7,"programme":8,"title":669,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":670},"cordis-marie-skłodowska-curie-actions-award-625328","Integrated study of skin resident Memory T cells and dermal mononuclear phagocytes in the fight against PATHogens","\"Integrated study of skin resident Memory T cells and dermal mononuclear phagocytes in the fight against PATHogensControl of pathogen infection requires the generation of a tightly regulated immune response that recognizes the invading pathogen and that limits a potentially harmful host response. Recent work highlighted that resident memory T cells (TRM) form a very potent means of establishing effective immunity against infection. In the skin, I contributed to the extensive characterization of ",{"id":672,"funder":7,"programme":8,"title":673,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":674},"cordis-marie-skłodowska-curie-actions-award-327648","Cell-type-specific identification of mRNAs translated by cannabinoids in the hippocampus: from signaling to behavior","The hippocampal region is critically involved in memory formation and cannabinoids including delta9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, are known to impair hippocampus-dependent memories. Previous findings uncover the role of the mammalian target of rapamycin (mTOR) signaling pathway and protein synthesis underlying the long-term amnesic-like effects of THC. Thus, the regulation of mTOR-dependent mRNA translation after THC exposure could be an important proce",{"id":676,"funder":7,"programme":8,"title":677,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":678},"cordis-marie-skłodowska-curie-actions-award-622853","Study on methylation as risk and prognostic factor for breast cancer","Throughout life, methylation of DNA plays an important role in normal and appropriate regulation of gene expression. Many gene-specific changes in methylation have been described in the context of disease predisposition, development and progression, including cancer. However, the literature for breast cancer is still sparse.The hypothesis of this research proposal is that aberrant methylation of DNA in some genes plays an important role in breast carcinogenesis and progression. Specifically, the",{"id":680,"funder":7,"programme":8,"title":681,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":682},"cordis-marie-skłodowska-curie-actions-award-624740","Functional Genomics Analysis of Neisseria meningitidis interactions with human dermal blood vessels in vivo","Neisseria meningitidis is still the major cause of bacterial meningitis and septicemia worldwide. The septic shock caused by Neisserial invasive disease is characterized by the presence of skin lesions (petecchial rashes and purpura). Despite the strong association of meningococcal disease and purpura as well as the serious prognosis associated with it, the bacterial factors and physiological processes underlying these events at molecular and cellular level are still largely undescribed.Here we ",{"id":684,"funder":7,"programme":8,"title":685,"piName":10,"institution":686,"country":158,"year":13,"amount":210,"abstract":687},"cordis-marie-skłodowska-curie-actions-award-625862","Identification, characterization and mechanisms of action of new tumor-associated lymphangiogenesis inhibitors","UNIVERSITE DE LIEGE","Cancer and tumor metastasis is the largest single cause of death in both, men and women, claiming over 7 million lives each year worldwide and, it is expected that by 2020 the number of dead cancer patients will grow to 10 million per year. Metastatic tumor cells utilize blood and lymphatic vessels as routes for dissemination and it is well known that lymphatic vasculature serves as a major route for tumor metastasis. Besides, lymphangiogenesis, the new lymphatic vessels formation from pre-exist",{"id":689,"funder":7,"programme":8,"title":690,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":691},"cordis-marie-skłodowska-curie-actions-award-328098","Advanced stellar spectroscopy in the Gaia era","A new generation of surveys has begun the collection of high-resolution spectra for millions of individual stars in the Milky-Way Galaxy. In the frameworks of the Gaia-ESO and HERMES surveys, international research teams will decipher the information and derive precise chemical abundances and stellar parameters with unprecedently large statistics. In a year’s time, the Gaia satellite will begin its mission to complement the data with stellar distances and kinematics. The knowledge of chemical co",{"id":693,"funder":7,"programme":8,"title":694,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":695},"cordis-marie-skłodowska-curie-actions-award-623486","Genomic of adaptation in selfing polyploid species: the case of Capsella bursa-pastoris","The main goal of this IEF proposal is to allow the fellow to acquire all the competencies to develop, carry out, and lead his own research group in plant population genomics integrating functional approaches, with a special emphasis on the use of next generation sequencing (NGS) data. The fellow will complement his skills in theoretical population genetics and evolutionary genomics by acquiring new skills in the analyses of population genomic data, gene expression, and association mapping. Thank",{"id":697,"funder":7,"programme":8,"title":698,"piName":10,"institution":389,"country":107,"year":13,"amount":10,"abstract":699},"cordis-marie-skłodowska-curie-actions-award-627766","Infants predicting own and others’ actions: the neurocognitive development of action prediction","Predicting others’ actions is crucial for acting in a social world. How we come to these predictions is hotly debated. The simulation account states that the motor commands used to predict the sensory consequences of our own actions are also used to predict others’ actions. In contrast, rationality theory suggests that predictions of others’ actions are based on inborn, abstract rules and thus rely on a different mechanism than predictions of our own actions. To address this controversy, I sugge",{"id":701,"funder":7,"programme":8,"title":702,"piName":10,"institution":123,"country":39,"year":13,"amount":10,"abstract":703},"cordis-marie-skłodowska-curie-actions-award-626628","Optimal non-demolition quantum measurements","The goal of the project is the development and implementation of novel, highly efficient techniques for the quantum non-demolition measurement of photon number states. Cavity-QED experiments using Rydberg atoms to probe microwave fields stored in ultra-high finesse resonators have witnessed enormous progress in the past decades. Optimization of the information extraction rate will enable us to study new types of states which so far have been experimentally inaccessible due to their fast decohere",{"id":705,"funder":7,"programme":8,"title":706,"piName":10,"institution":661,"country":39,"year":13,"amount":10,"abstract":707},"cordis-marie-skłodowska-curie-actions-award-627487","THE ROLE OF ELASTASE\u002FELASTASE INHIBITOR IN DIALOG BETWEEN INTESTINAL EPITHELIAL CELLS AND MACROPHAGES IN INFLAMMATORY BOWEL DISEASES CONTEXT","Inflammatory Bowel Diseases (IBD) are chronic disorders for which aetiology is unknown and only palliative care is available for patients. In Europe, 2.2 million people suffered of ulcerative colitis or Crohn's disease in Europe, the socio-economic impact of IBD is very heavy. Thus, the development of new and more effective treatments for IBD depends upon a better understanding of the regulation of inflammatory response.The aims of this project are both:  firstly, provide evidence of contributio",{"id":709,"funder":7,"programme":8,"title":710,"piName":10,"institution":432,"country":59,"year":13,"amount":10,"abstract":711},"cordis-marie-skłodowska-curie-actions-award-626533","Searching for nature's best clocks and extragalactic millisecond transients with large interferometric arrays: from the GMRT to the SKA","Millisecond pulsars (MSPs) are rapidly rotating neutron stars that emit a beam of radio waves fromtheir magnetic poles. Their rate of rotation is very stable and so the pulses detected as they spin are likethe ticks of an extremely precise clock. Measuring small deviations in the rate that this clock runs makes themideal laboratories to test gravity theories and as detectors for gravitational waves. In addition to the regularradio emission from pulsars,  millisecond transient bursts (FRBs) are o",{"id":713,"funder":7,"programme":8,"title":714,"piName":10,"institution":686,"country":158,"year":13,"amount":210,"abstract":715},"cordis-marie-skłodowska-curie-actions-award-624639","Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci","Life-time prevalence of inflammatory bowel disease (IBD) is reaching an alarming rate of > 1\u002F400 in industrialized societies.  Improved understanding of disease pathogenesis is essential to develop more effective preventive, diagnostic and therapeutic measures.  Genome-wide association studies (GWAS) have identified ~ 160 risk loci contributing to inherited predisposition to Crohn's disease and\u002For ulcerative colitis.  While this has already led to the identification of new perturbed pathways and",{"id":717,"funder":7,"programme":8,"title":718,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":720},"cordis-marie-skłodowska-curie-actions-award-330134","Autoimmune Reaction or Tolerance - Endosymbiont Mitochondria and the Immune System","AARHUS UNIVERSITET","Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Because mitochondria retain many hallmarks of their bacterial origin, they have recently been implicated in the etiology of systemic inflammatory response syndrome, a frequent cause of death in intensive care units. Remarkably, mitochondria are immunologically inert under normal homeostatic conditions, raising the fundamental question: how does the immune system distinguish mitochondria from resemblant bacter",{"id":722,"funder":7,"programme":8,"title":723,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":724},"cordis-marie-skłodowska-curie-actions-award-629413","Adaptations of the ATP synthesis machinery in bacteria and archaea to conditions of extremeenergy limitation in the deep subsurface","Microbes in the deep sub-seafloor have recently been found to survive under unprecedented conditions of extreme energy limitation. I aim to identify microbes in these deep subsurface communities with central energy metabolism that is adapted to these conditions. A combination of single-cell genomics and metagenomics will be used to identify members of the microbial community adapted to low energy flux by use of Na+-based chemiosmotic ATP synthesis. Following sequencing, genes encoding c subunits",{"id":726,"funder":7,"programme":8,"title":727,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":728},"cordis-marie-skłodowska-curie-actions-award-624798","Proteomic explanations for the adaptive significance of kin recognition in subsocial spiders","Kin selection theory predicts that cooperation should evolve among kin to reduce the costs of helping and the incentive to cheat. Altruistic behaviour provides individuals with either direct or indirect fitness benefits. As a necessary prerequisite, individuals need to recognise kin to direct their help towards them. Thus, kin recognition is a key feature of many social animals. Ultimate benefits of altruism are well studied, but proximate mechanisms explaining the maintenance and early evolutio",{"id":730,"funder":7,"programme":8,"title":731,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":732},"cordis-marie-skłodowska-curie-actions-award-328645","Direct Nanosecond and Nanometer Scale Investigations of Nucleation and Growth Phenomena","This Marie Curie IIF proposal applies novel high speed Scanning Probe Microscopy to monitor nanoscale dynamics in order to investigate fundamental materials science challenges impacting a promising class of future data storage materials.The proposal builds on 13 years in academia, national labs, and European research labs (Oxford, EPFL, Aarhus) since earning a PhD. Huey has since raised >$5M for team projects with $2.6M for his lab, published >40 papers, collaborated with scientists from 8 disti",{"id":734,"funder":7,"programme":8,"title":735,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":736},"cordis-marie-skłodowska-curie-actions-award-626764","Computation-driven rational design of MoSx-based desulphurization nanocatalysts","The aim of the Nano-DeSign project is to rationally design a new generation of improved nanostructured MoS2 heterogeneous catalysts by means of computational modelling that will lead the way, in close collaboration with experimental and industrial partners, towards the engineering and use of real world desulphurization catalysts. The combustion of S-containing fossil fuels supposes a threat for the environment (acid rain) as well as for human health in largely populated and industrialized areas.",{"id":738,"funder":7,"programme":8,"title":739,"piName":10,"institution":740,"country":107,"year":13,"amount":10,"abstract":741},"cordis-marie-skłodowska-curie-actions-award-326930","Kinetic analysis of molecular profiles during human induced regulatory T cell (iTreg) differentiation: an integrative study","KAROLINSKA INSTITUTET","Regulatory T cells (Tregs) suppress other immune cells and, thus, are critical mediators of peripheral self-tolerance, preventing autoimmune disease but hampering tumor rejection. Therapeutic manipulations of Treg number and function are therefore subject to numerous clinical investigations. First in-man trials of adoptive Treg transfer to prevent graft-versus-host disease showed very promising outcomes. Yet, the number of naturally occurring Tregs (nTregs) is minute, encouraging the complementa",{"id":743,"funder":7,"programme":8,"title":744,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":745},"cordis-marie-skłodowska-curie-actions-award-622413","Asymmetric organocatalysts for remote functionalization strategies","Research in the area of aminocatalysis moves at breathtaking speed: many catalytic reactions now considered to be “standard issue” by organic chemists were almost unthinkable just 10 years ago. The development of new catalysts often makes it possible to generate previously unattainable compounds, which could have unique physical, chemical or biological properties. But the basic science is as important as the applications: studies of catalytic mechanisms often uncover new modes of chemical reacti",{"id":747,"funder":7,"programme":8,"title":748,"piName":10,"institution":590,"country":96,"year":13,"amount":10,"abstract":749},"cordis-marie-skłodowska-curie-actions-award-623764","Social determinants and ecological impacts of seed transmission systems in African root and tuber crops, and their implications for resilience of smallholder farming systems","Understanding the processes by which smallholder farmers in developing countries increase or renew crop diversity, and how they maintain this diversity by ensuring the transmission of their technical and ecological knowledge through the generations, is essential for tackling food insecurity whilst at the same time conserving agricultural biodiversity. The KINSEED project focuses on seed transmission systems as a determining factor of the adaptive capacity of smallholder farming societies in a co",{"id":751,"funder":7,"programme":8,"title":752,"piName":10,"institution":740,"country":107,"year":13,"amount":10,"abstract":753},"cordis-marie-skłodowska-curie-actions-award-626544","Epigenetic mechanisms underlying inter-individual differences in drug response and hepatic disease","Inter-individual differences in reaction to drugs and pharmacological treatments can cause severe adverse drug reactions (ADRs) and are a common reason of withdrawal of drugs from the market. ADRs are as costly for society as treatment itself and are a major cause of hospitalizations and deaths. Genetic polymorphisms in genes encoding enzymes involved in drug metabolism can only explain a small subset of the inter-individual differences in response to pharmacological treatment. Recently, the hos",{"id":755,"funder":7,"programme":8,"title":756,"piName":10,"institution":590,"country":96,"year":13,"amount":10,"abstract":757},"cordis-marie-skłodowska-curie-actions-award-622414","The Manufacturing of Scaffolds from Novel Coated Microspheres via Additive Manufacturing Techniques for Temporomandibular Joint Tissue Engineering","The project goal is to manufacture scaffolds for tissue engineering from novel coated microspheres. Such scaffolds have a high potential to be used in bone and cartilage regeneration in orthopaedic or temporomandibular joint (TMJ) applications. Monodisperse microspheres that allow encapsulation of growth factors have been developed at the University of Kansas (KU). Prof. Detamore from KU and I worked on using selective laser sintering (SLS) to sinter microspheres that have a coating to satisfy b",{"id":759,"funder":7,"programme":8,"title":760,"piName":10,"institution":761,"country":184,"year":13,"amount":10,"abstract":762},"cordis-marie-skłodowska-curie-actions-award-622811","MicroRNA targeting to achieve Systemic Sclerosis Control and Prediction","UNIVERSITAIR MEDISCH CENTRUM UTRECHT","Systemic Sclerosis (SSc) is a disfiguring disease with high mortality and morbidity, characterized by progressive and uncontrollable fibrosis of the skin and internal organs. There is no successful therapy for SSc resulting in a markedly shortened life expectancy, usually less that most cancers. Moreover, SSc diagnosis is very difficult in the early phase of the disease; consequently patient treatment is delayed until skin and\u002For internal organ involvement is evident and already irreversible. Th",{"id":764,"funder":7,"programme":8,"title":765,"piName":10,"institution":761,"country":184,"year":13,"amount":10,"abstract":766},"cordis-marie-skłodowska-curie-actions-award-624871","The Expression of CXC chemokine ligand 4 in Systemic Sclerosis and its Role in the regulation of immune and fibrotic responses","Systemic sclerosis (SSc) is a chronic inflammatory disorder in which excessive fibrosis occurs in all vital organs, leading to profound disability and premature death. The pathogenesis of SSc is still unclear. Although earlier studies focused on fibroblast biology and pro-fibrotic factors, recently evidence advocates an important role of immune cells in the pathogenesis of this disease. In the last few years Prof. Radstake's has focused on immune cell subsets, in particular on plasmacytoid dendr",{"id":768,"funder":7,"programme":8,"title":769,"piName":10,"institution":770,"country":12,"year":13,"amount":10,"abstract":771},"cordis-marie-skłodowska-curie-actions-award-627441","Membrane lipid composition as new antitumor therapeutic target: sphingomyelin synthase (SGMS) at the basis of Minerval® mechanism of action and design of new Minerval®-related drugs","UNIVERSITAT DE LES ILLES BALEARS","MembraneLipidTherapy proposal is a translational research project introducing an innovative therapeutic approach for fighting cancer disease that takes advantage of inter-sectoral industry-academia strengths and international cooperation.Membrane Lipid Therapy relies on the specific lipid composition from the cell membrane in tumour cells as a strong element controlling tumour growth surpassing oncogene activation or tumour suppressor inactivation. Particularly the ratio of membrane lipids phosp",{"id":773,"funder":7,"programme":8,"title":774,"piName":10,"institution":740,"country":107,"year":13,"amount":10,"abstract":775},"cordis-marie-skłodowska-curie-actions-award-331112","Inhibition and neuromodulation in oscillation and synchrony","Cognition depend on the cooperation and communication between functionally connected brain areas. Oscillation and synchrony appear to be crucial for the engagement and disengagement of functional neural circuits. Many studies suggest inhibitory neurons in the brain dictates how and when the information is relayed between neuronal ensembles. The valence of these excitation-inhibition interactions are further regulated by neuromodulators such as dopamine (DA) and the diversity of differential expr",{"id":777,"funder":7,"programme":8,"title":778,"piName":10,"institution":590,"country":96,"year":13,"amount":10,"abstract":779},"cordis-marie-skłodowska-curie-actions-award-629256","Networks of Trade and Religion in Richard Hakluyt's 'Principal Navigations'","This proposal will enhance the career development of the IEF through a research project that engages with Richard Hakluyt’s 'Principal Navigations' the most important collection of early modern English travel writing. The project will introduce a more sophisticated understanding of religious identity into the discussion of Hakluyt and his sources. In light of recent research on religious identity formation, we can no longer label Hakluyt as simply a staunch Protestant when he featured material f",{"id":781,"funder":7,"programme":8,"title":782,"piName":10,"institution":719,"country":118,"year":13,"amount":10,"abstract":783},"cordis-marie-skłodowska-curie-actions-award-622936","Investigating the joint role of balancing and positive selection in mating systems evolution","Determining the evolutionary causes of sexual reproduction remains one of the biggest open questions in biology. Investigations of facultative sexuals can shed substantial insight on this subject due to the span of mating systems exhibited, ranging from outcrossing to asexual reproduction. Due to the widespread availability and reduced cost of sequencing technologies, it is now feasible to perform detailed genomic analysis of many individuals, and combine these data with mathematical models to d",{"id":785,"funder":7,"programme":8,"title":786,"piName":10,"institution":787,"country":184,"year":13,"amount":10,"abstract":788},"cordis-marie-skłodowska-curie-actions-award-622415","Synthesis of trifluoromethylstyrene compounds via gas-liquid photoredox catalysis in continuous-flow microreactors","TECHNISCHE UNIVERSITEIT EINDHOVEN","In this Marie Curie proposal, trifluoromethylstyrene compounds will be prepared via gas-liquid two-phase photoredox catalysis in a continuous-flow microfluidic system. Different influencing factors such as catalysts, substrates, solvents, light irradiation, temperature, and residence time will be systematically investigated. In order to thoroughly understand the reaction mechanisms of gas-liquid photoredox catalysis for synthesis of trifluoromethylstyrene compounds, we will study its reaction ki",{"id":790,"funder":7,"programme":8,"title":791,"piName":10,"institution":792,"country":45,"year":13,"amount":10,"abstract":793},"cordis-marie-skłodowska-curie-actions-award-626643","Study of Structure-Property-Process relations in real functional FOODs","ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA","In the context of current economic and social changes, the research in the agri-food area should aim, among other things, to the optimization of products and processes. The improvement of the food products must be directed towards ensuring the nutritional and specific functional benefit. Regarding the improvement of processes, they should ensure the quality and safety of environmentally friendly food products produced optimizing the use of resources.A research activity focused on fundamental ana",{"id":795,"funder":7,"programme":8,"title":796,"piName":10,"institution":792,"country":45,"year":13,"amount":10,"abstract":797},"cordis-marie-skłodowska-curie-actions-award-622974","TELESTES. Musics, cults and rites of a Greek city in the West","This project is dedicated to the musical culture of Selinus, one of the most important Western Greek cities, noted for its investment in cult and religious practice. The project is part of a broader research, concerning the appreciation of the Ancient Greek musical heritage in its historical context, identified here with the musical history of a Greek city in the West from the Archaic down to the Hellenistic period. The study combines the methods of archeology and musicology towards the analysis",{"id":799,"funder":7,"programme":8,"title":800,"piName":10,"institution":787,"country":184,"year":13,"amount":10,"abstract":801},"cordis-marie-skłodowska-curie-actions-award-330340","Plasmonics of Quantum Materials: from surface plasmon condensation to quantum metamaterials","Interfacing quantum optics with nanotechnology could boost the prospects for the integration of scalable quantum information technologies. Quantum information processing is a key future technology that promises superior communication and computing performance beyond classical information. Any candidate to realize its full potential will require solid-state coherent units with long-range interactions. The most promising approaches rely on photons and spins.Recent demonstrations of the quantized c",{"id":803,"funder":7,"programme":8,"title":804,"piName":10,"institution":805,"country":39,"year":13,"amount":10,"abstract":806},"cordis-marie-skłodowska-curie-actions-award-625039","Evolutionary morphology of accessory auditory structures in piranhas, pacus, and related serrasalmid fishes: is acute hearing an adaptation for prey location?","MUSEUM NATIONAL D'HISTOIRE NATURELLE","The evolutionary success of otophysans, a major lineage of fish diversity, is often attributed to a novel morphology involving unique bones, anterior vertebrae, and the swim bladder. This feature, termed the Weberian apparatus (WA), is an accessory hearing organ that transduces sound from the swim bladder to the inner ear. As a result, otophysans have sensitive hearing, however, the adaptive function for such ability is unknown. Further, the effect of WA morphological variation between species i",{"id":808,"funder":7,"programme":8,"title":809,"piName":10,"institution":810,"country":65,"year":13,"amount":10,"abstract":811},"cordis-marie-skłodowska-curie-actions-award-624183","Investigation of Greenland temperature variability over the 6000 years using trapped air in ice cores","UNIVERSITAET BERN","Greenland temperature is one of the most important variables when considering future climate change, as it has the potential to impact a significant percentage of the population through an increase of the global sea level resulting from the melting of the Greenland ice sheet. Therefore, it is critical to understand the mechanism of Greenland temperature variability over multidecadal to centennial time scales with societal relevance. A new method has been developed to reconstruct Greenland temper",{"id":813,"funder":7,"programme":8,"title":814,"piName":10,"institution":761,"country":184,"year":13,"amount":10,"abstract":815},"cordis-marie-skłodowska-curie-actions-award-627575","Imaging Innate Immunity of Staphylococcal Infections","Staphylococcus aureus community-acquired (CA)-MRSA strains are highly virulent and can cause infections in otherwise healthy individuals and are a leading cause of death worldwide. Innate immunity is our primary defense against invading staphylococci. Blood-neutrophils migrate to the site of infection where they, in concert with the complement system, engulf and kill bacteria in a process called phagocytosis. Especially CA-MRSA strains seem to be very efficient in circumventing this neutrophil k",{"id":817,"funder":7,"programme":8,"title":818,"piName":10,"institution":819,"country":184,"year":13,"amount":10,"abstract":820},"cordis-marie-skłodowska-curie-actions-award-327091","Managing diversity in the EU: The cultural open method of coordination revisited","UNIVERSITEIT MAASTRICHT","OPENCULT focuses on the use of the open method of coordination (OMC) as one of the new cultural policy tools employed by the EU in the wake of the European Agenda for Culture in a Globalizing World (COM(2007) 242). The project will study the configuration of the cultural OMC, the institutional structures and policy objectives that define it, and the complex array of policy processes and instruments that it involves. It will explore whether the cultural OMC has led to the development of more cult",{"id":822,"funder":7,"programme":8,"title":823,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":824},"cordis-marie-skłodowska-curie-actions-award-624450","Global existence vs Blow-up in some nonlinear PDEs arising in fluid mechanics","The present project aims at studying qualitative properties of some nonlinear Partial Differential Equations arising in fluid mechanics. It is divided into 3 parts.Part 1 and Part 2 address the study  of some classes of 1D hydrodynamic models, namely, the inviscd Surface Quasi-Gesotrophic equation (SQG)  and the generalized Constantin-Lax-Majda (gCLM) equation. Both models are closely related to the 3D Euler equation written in terms of the vorticity and are therefore mathematically interesting.",{"id":826,"funder":7,"programme":8,"title":827,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":828},"cordis-marie-skłodowska-curie-actions-award-628146","Macrobenthic communities associated with deep wood falls lying in submarine canyons","Life in the deep-sea ecosystems is generally dependent on the constant rain and fall of particles and matter from the photic zone and the continental shelf. Submarine canyons may trap and concentrate large organic falls (e.g. terrestrial debris and sunken wood) from wide areas. Its accumulation on canyon floor creates “islands” that contribute to deep-sea species diversity and dispersal. Therefore, it is widely accepted that submarine canyons may play a significant role in enhancing shelf-basin ",{"id":830,"funder":7,"programme":8,"title":831,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":832},"cordis-marie-skłodowska-curie-actions-award-331450","Comparative Genomics and Environmental Diversity of Coral Associated Apicomplexa-Related Lineages","Coral reefs are home to the greatest density of species in shallow marine waters, including unusually diverse microbial communities. However, almost everything we know about reef microbial communities is confined to prokaryotes and viruses: next to nothing is known about the microbial eukaryotes, with the exception of the symbiont dinoflagellate Symbiodinium. Coral reefs are like most other marine environments, where protists are consistently overlooked. Chromera and Vitrella are two reef-associ",{"id":834,"funder":7,"programme":8,"title":835,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":836},"cordis-marie-skłodowska-curie-actions-award-624351","How active black holes shape the Universe: beyond Hubble","Super-massive black holes in the centers of galaxies have active phases during which they are believed to expel large amounts of gas, quench star formation and shape the evolution of the entire galaxy. Multi-wavelength searches for this destructive `feedback' force are ongoing, with the goal of answering two key questions: is black-hole feedback devastating and common enough to play a key role in the evolution of the Universe? And what is the physical mechanism behind this force of evolution?Dri",{"id":838,"funder":7,"programme":8,"title":839,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":840},"cordis-marie-skłodowska-curie-actions-award-330655","Artificial night lights and seabirds: solutions to a fatal attraction","During the last decades, artificial lighting have been increasing at a rate of 6% the World, increasing the light pollution levels. Currently, lighting constitutes the 16% of global electricity. The European Ecodesign Directive established a framework to phase out particularly energy-intensive lights. Until now, economic and energetic optimization has solely driven eco-friendly lighting strategies. Policy objectives should not only target economic optimisation, but also consider the cultural, so",{"id":842,"funder":7,"programme":8,"title":843,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":844},"cordis-marie-skłodowska-curie-actions-award-331190","Dynamics, genomics and functional significance of uncultured marine Stramenopiles","Most of the biodiversity in oceans is constituted by microbes which dominate the biomass and have key roles in ecosystem functioning and biogeochemical cycling. Recent culture-independent studies of marine planktonic protists have unveiled a large diversity at all phylogenetic scale, notably among the heterotrophic microeukaryotes compartment (2-5 µm cell size), and the existence of novel groups. Among these novel uncultured lineages, Marine Stramenopiles groups (MASTs) are essentially composed ",{"id":846,"funder":7,"programme":8,"title":847,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":848},"cordis-marie-skłodowska-curie-actions-award-622533","INTEGRATION OF PHOTONIC NANOSTRUCTURES IN FLEXIBLE DYE SOLAR CELLS","It is the main goal of this project to bring to the host institution and the European Research Area the knowledge and technology to prepare current record flexible dye sensitized photovoltaic devices, previously developed by the candidate in South Korea and then the USA, in order to be able to further improve them, while endowing them with semi-transparency, using stretchable and bendable optical materials. The candidate has demonstrated that several key materials and processes provide better pe",{"id":850,"funder":7,"programme":8,"title":851,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":852},"cordis-marie-skłodowska-curie-actions-award-625997","Genetic map of European butterflies: Continental-scale cryptic species assessment and comparisons to North America and Australia","There is a widely recognized need for more comprehensive understanding of patterns of global biodiversity. Such information will not only address major scientific issues, such as the factors influencing rates of speciation, but it will also add new rigor to conservation programs (a critical need given the looming extinction crisis). This project exploits the power of DNA barcoding to deliver a synoptic overview of biodiversity patterns, and focuses this analysis on butterflies as a model system ",{"id":854,"funder":7,"programme":8,"title":855,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":856},"cordis-marie-skłodowska-curie-actions-award-328689","Understanding the nature and origin of black deposits in caves: new insights on enigmatic microorganisms and secondary minerals valuable for astrobiology","The advent of powerful new tools, the need to better understand the biodiversity, origins of life on Earth and on other planets, and the wide applications of the microbe-mineral interactions, have led to a rapid expansion of interest in subsurface environments. Recently reported results indicate signs of an early wet Mars and rather recent volcanic activity which suggest that Mars’s subsurface can house organic molecules or traces of microbial life, making the search for microbial life on Earth’",{"id":858,"funder":7,"programme":8,"title":859,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":860},"cordis-marie-skłodowska-curie-actions-award-330222","From large-scale distribution patterns to efficient conservation plans","Distinguishing historical from environmental effects on species' distributions is crucial for effective conservation planning, especially under changing environmental conditions: we need to know how strongly each species responds to the environment. Data sets with explicit information (fossil records, physiological experiments) are rare, and environmental models applied so far have unverified assumptions and often ungrounded conclusions. I aim to improve the efficiency of data analysis and conse",{"id":862,"funder":7,"programme":8,"title":863,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":864},"cordis-marie-skłodowska-curie-actions-award-331623","Spatial variation in community structure: species, functional and phylogenetic diversity at different scales","Unifying community ecology and biogeography is essential for the advance of ecological research. Although spatial scale is known to be important to understand community structure, current knowledge on spatial variation of functional and phylogenetic diversity is limited. COMMSTRUCT aims to study how community structure and assembly vary in space across different extents and scales.Community structure can be described through different parameters, from species richness to composition in terms of ",{"id":866,"funder":7,"programme":8,"title":867,"piName":10,"institution":543,"country":12,"year":13,"amount":10,"abstract":868},"cordis-marie-skłodowska-curie-actions-award-627384","Implementation of a Novel Brain Machine Interface to Restore Limb Movement and Promote Recovery from Partial Spinal Cord Injury: Basic Studies and Clinical Application","Spinal cord injury causes alterations in the central nervous system, as well as the sensorimotor and autonomic systems below the injury, and has devastating personal and socioeconomic costs. Although there is currently no cure, new research opportunities offer the prospect of accelerating both our understanding of the disorder, and the design of therapies to promote recovery. I will investigate, in both animal models and patients, a novel rehabilitation technique that consists of a brain-machine",{"id":870,"funder":7,"programme":8,"title":871,"piName":10,"institution":872,"country":184,"year":13,"amount":10,"abstract":873},"cordis-marie-skłodowska-curie-actions-award-623046","Quantum Chemistry of Enzymatic Nucleophilic Substitution: Untangling the Role of Metal Ions and Protein Environment in Biochemical Nucleophilic Substitution at Phosphorus and Sulfur","STICHTING VU","Enzymatic nucleophilic substitution reactions are ubiquitous as key steps in biochemical processes of living cells. Despite their importance, they are poorly understood, in particular regarding the exact mechanism and involvement of the protein environment and the role and mechanistic involvement of metal ions. Through interpretative methods from chemical reactivity theory, I will  tackle the missing links in this field of molecular life sciences. This project thus goes beyond transition state c",{"id":875,"funder":7,"programme":8,"title":876,"piName":10,"institution":872,"country":184,"year":13,"amount":10,"abstract":877},"cordis-marie-skłodowska-curie-actions-award-629625","Time-dependent density functional theory for strongly-interacting electrons","This proposal aims at developing a new theoretical framework for the description of quantum transport and optical properties of strongly-correlated many-electron systems. The project is based on the exact infinite-coupling-strength limit of density functional theory (DFT), the so-called Strictly-Correlated-Electron (SCE) functional, which has been largely developed by the host scientist for ground-state DFT. Using my expertise in time-dependent (TD) DFT and Green's functions theory, I will exten",{"id":879,"funder":7,"programme":8,"title":880,"piName":10,"institution":881,"country":158,"year":13,"amount":210,"abstract":882},"cordis-marie-skłodowska-curie-actions-award-622848","Infrahumanization:The Effects of Uniquely Human and Non-Uniquely Human Emotions on Justice","UNIVERSITE CATHOLIQUE DE LOUVAIN","This project will examine the role of infra-humanization and group membership in administration of justice for violation of moral rules. Justice theory distinguishes certain criteria, such as intentionality of the harm-doer, that are considered for the restoration of justice. Intentional harms require both compensation in favor of the victim and punishment of the harm-doer. Two different kinds of punishment have been detected; retributive, is a proportionate to the harm punishment (a more lenien",{"id":884,"funder":7,"programme":8,"title":885,"piName":10,"institution":881,"country":158,"year":13,"amount":886,"abstract":887},"cordis-marie-skłodowska-curie-actions-award-627999","Technological use disorders: European cross-cultural longitudinal and experimental studies for Internet and smartphone problem uses","€227,800","This research project consists in study the technological use disorders (based on Internet and smartphone) in European problem users, to estimate prevalence, psychosocial profiles, as well as to ascertain psychological factors involved in the development and maintenance of these disorders.This Marie Curie 2013 proposal covers one overall research with two underlying studies:First study, an online survey for cross-cultural longitudinal study with 10 European countries (in three waves) to estimate",200,{"programme":8,"total":890,"withPiName":891,"firstYear":892,"lastYear":893,"countryCount":894,"perYear":895,"topInstitutions":971,"topCountries":1047},26094,19,1988,2027,53,[896,898,901,904,907,910,913,916,919,922,925,928,931,933,936,939,942,945,948,951,954,957,960,963,966,969],{"year":892,"count":897},1,{"year":899,"count":900},2003,74,{"year":902,"count":903},2004,586,{"year":905,"count":906},2005,868,{"year":908,"count":909},2006,641,{"year":911,"count":912},2007,553,{"year":914,"count":915},2008,591,{"year":917,"count":918},2009,712,{"year":920,"count":921},2010,787,{"year":923,"count":924},2011,838,{"year":926,"count":927},2012,901,{"year":929,"count":930},2013,1005,{"year":13,"count":932},1009,{"year":934,"count":935},2015,1232,{"year":937,"count":938},2016,1231,{"year":940,"count":941},2017,1209,{"year":943,"count":944},2018,1353,{"year":946,"count":947},2019,1340,{"year":949,"count":950},2020,1314,{"year":952,"count":953},2021,1688,{"year":955,"count":956},2022,1362,{"year":958,"count":959},2023,1495,{"year":961,"count":962},2024,1522,{"year":964,"count":965},2025,1781,{"year":967,"count":968},2026,1532,{"year":893,"count":970},396,[972,975,978,981,984,987,990,993,996,999,1002,1005,1008,1011,1014,1017,1020,1023,1026,1029,1032,1035,1038,1041,1044],{"name":973,"count":974},"Centre National de la Recherche Scientifique CNRS",790,{"name":976,"count":977},"The Chancellor Masters and Scholars of the University of Cambridge",636,{"name":979,"count":980},"Kobenhavns Universitet",614,{"name":982,"count":983},"Chancellor, Masters and Scholars of the University of Oxford",579,{"name":985,"count":986},"Agencia Estatal Consejo Superior de Investigaciones Cientificas",484,{"name":988,"count":989},"Imperial College of Science Technology and Medicine",428,{"name":991,"count":992},"Max-Planck-Gesellschaft zur Forderung der Wissenschaften Ev",383,{"name":994,"count":995},"University of London",347,{"name":997,"count":998},"Katholieke Universiteit Leuven",280,{"name":1000,"count":1001},"The University of Birmingham",247,{"name":1003,"count":1004},"Eidgenoessische Technische Hochschule Zuerich",224,{"name":1006,"count":1007},"Aarhus Universitet",220,{"name":1009,"count":1010},"Universita Ca' Foscari  Venezia",219,{"name":1012,"count":1013},"University of Bristol",213,{"name":1015,"count":1016},"Ecole Polytechnique Federale de Lausanne",182,{"name":1018,"count":1019},"The University of Edinburgh",181,{"name":1021,"count":1022},"Universita Degli Studi di Padova",177,{"name":1024,"count":1025},"Universitat Wien",175,{"name":1027,"count":1028},"University of Leeds",169,{"name":1030,"count":1031},"Universiteit van Amsterdam",159,{"name":1033,"count":1034},"Universitetet I Oslo",156,{"name":1036,"count":1037},"Universiteit Utrecht",152,{"name":1039,"count":1040},"Technische Universiteit Delft",142,{"name":1042,"count":1043},"University of Warwick",141,{"name":1045,"count":1046},"Institut National de la Sante Et de la Recherche Medicale",139,[1048,1050,1052,1054,1056,1058,1060,1062,1064,1066,1068,1070,1072,1074,1077,1079,1081,1084,1087,1090,1092,1095,1097,1100,1103],{"name":59,"count":1049},5982,{"name":39,"count":1051},2854,{"name":12,"count":1053},2844,{"name":28,"count":1055},2362,{"name":45,"count":1057},2058,{"name":184,"count":1059},1624,{"name":118,"count":1061},1173,{"name":65,"count":1063},1075,{"name":158,"count":1065},996,{"name":107,"count":1067},788,{"name":170,"count":1069},634,{"name":96,"count":1071},608,{"name":510,"count":1073},487,{"name":1075,"count":1076},"PT",482,{"name":621,"count":1078},313,{"name":631,"count":1080},277,{"name":1082,"count":1083},"CZ",256,{"name":1085,"count":1086},"IL",168,{"name":1088,"count":1089},"TR",147,{"name":80,"count":1091},137,{"name":1093,"count":1094},"SI",113,{"name":134,"count":1096},99,{"name":1098,"count":1099},"HU",97,{"name":1101,"count":1102},"LU",59,{"name":1104,"count":1105},"LT",56]