[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-nwo-vici-2015":3,"awarded-stats-nwo-vici":55},{"awarded":4,"total":54},[5,16,22,29,36,42,47],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-680-47-607","Nederlandse Organisatie voor Wetenschappelijk Onderzoek","NWO Vici","Speeding up biomolecular interactions by molecular sledding","Andreas Herrmann","University of Groningen","NL",2015,null,"Numerous biological processes involve association of a protein with its binding partner, an event that is preceded by a diffusion-mediated search bringing the two partners together. Often hindered by crowding in biologically relevant environments, three-dimensional diffusion can be slow and result in long bimolecular association times. Similarly, the initial association step between two binding partners often represents a rate-limiting step in biotechnologically relevant reactions. We demonstrat",{"id":17,"funder":7,"programme":8,"title":18,"piName":19,"institution":20,"country":12,"year":13,"amount":14,"abstract":21},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-700-58-442","Primary Nucleation Kinetics of Short Fibril-Forming Amyloidogenic Peptides","Jurriaan A. Luiken","University of Amsterdam","The primary nucleation step in amyloid fibril formation can, depending on the nature of peptide sequence, occur in one step, straight from a dilute solution, or in multiple steps, via oligomers or disordered aggregates. The precise kinetic pathways of these processes are poorly understood. Employing forward flux sampling and a midresolution coarse-grained force field, we analyzed the reactive pathways from the solvated state to the fibril nucleus for a system of 12 amyloidogenic peptides. In lin",{"id":23,"funder":7,"programme":8,"title":24,"piName":25,"institution":26,"country":27,"year":13,"amount":14,"abstract":28},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-grant-639-033-008-","Quadratic and rate-independent limits for a large-deviations functional","Giovanni A. Bonaschi","University of Pavia","IT","We construct a stochastic model showing the relationship between noise, gradient flows and rate-independent systems. The model consists of a one-dimensional birth–death process on a lattice, with rates derived from Kramers’ law as an approximation of a Brownian motion on a wiggly energy landscape. Taking various limits, we show how to obtain a whole family of generalized gradient flows, ranging from quadratic to rate-independent ones, connected via ‘L log L’ gradient flows. This is achieved via ",{"id":30,"funder":7,"programme":8,"title":31,"piName":32,"institution":33,"country":34,"year":13,"amount":14,"abstract":35},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-10817","Redeposition in plasma-assisted atomic layer deposition: Silicon nitride film quality ruled by the gas residence time","Harm C. M. Knoops","Oxford Instruments (United Kingdom)","GB","The requirements on the material properties and growth control of silicon nitride (SiNx) spacer films in transistors are becoming ever more stringent as scaling of transistor structures continues. One method to deposit high-quality films with excellent control is atomic layer deposition (ALD). However, depositing SiNx by ALD has turned out to be very challenging. In this work, it is shown that the plasma gas residence time τ is a key parameter for the deposition of SiNx by plasma-assisted ALD an",{"id":37,"funder":7,"programme":8,"title":38,"piName":39,"institution":40,"country":12,"year":13,"amount":14,"abstract":41},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vici-700-58-441","Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling","Yoshitaka Hiruma","Dutch Cancer Society","Cell division progresses to anaphase only after all chromosomes are connected to spindle microtubules through kinetochores and the spindle assembly checkpoint (SAC) is satisfied. We show that the amino-terminal localization module of the SAC protein kinase MPS1 (monopolar spindle 1) directly interacts with the HEC1 (highly expressed in cancer 1) calponin homology domain in the NDC80 (nuclear division cycle 80) kinetochore complex in vitro, in a phosphorylation-dependent manner. Microtubule polym",{"id":43,"funder":7,"programme":8,"title":44,"piName":45,"institution":14,"country":14,"year":13,"amount":14,"abstract":46},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vici-453-03-606","Equilibrium Selection in Experimental Cheap Talk Games","Adrian de Groot Ruiz","In the past, many refinements have been proposed to select equilibria in cheap talk games. Usually, these refinements were motivated by a discussion of how rational agents would reason in some particular cheap talk games. In this paper, we propose a new refinement and stability measure that is intended to predict actual behavior in a wide range of cheap talk games. According to our Average Credible Deviation Criterion (ACDC), the stability of an equilibrium is determined by the frequency and siz",{"id":48,"funder":7,"programme":8,"title":49,"piName":50,"institution":51,"country":52,"year":13,"amount":14,"abstract":53},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-680-47-602","Точный спектр и зеркальная дуальность $(AdS_5\\times S^5)_\\eta$-суперструны","Gleb Arutyunov","Universität Hamburg","DE","Обсуждается спектр струны, распространяющейся в $\\eta$-деформированном\\linebreak пространстве $AdS_5\\times S^5$. Для этого ее теория на мировом листе представляется в терминах интегрируемой квантовой теории поля. Точная $S$-матрица этой теории задается $q$-деформацией $S$-матрицы теории на мировом листе пространства $AdS_5\\times S^5$ с вещественным параметром деформации. Рассматривая зеркальные (с двойным виковским поворотом) версии этих теорий на мировом листе, с помощью термодинамического анза",7,{"programme":8,"total":56,"withPiName":56,"firstYear":57,"lastYear":58,"countryCount":59,"perYear":60,"topInstitutions":105,"topCountries":161},296,2008,2026,18,[61,63,65,67,70,73,74,77,80,83,86,88,91,94,97,100,103],{"year":57,"count":62},1,{"year":64,"count":62},2011,{"year":66,"count":62},2012,{"year":68,"count":69},2013,3,{"year":71,"count":72},2014,4,{"year":13,"count":54},{"year":75,"count":76},2016,14,{"year":78,"count":79},2017,44,{"year":81,"count":82},2018,65,{"year":84,"count":85},2019,9,{"year":87,"count":59},2020,{"year":89,"count":90},2021,16,{"year":92,"count":93},2022,22,{"year":95,"count":96},2023,27,{"year":98,"count":99},2024,26,{"year":101,"count":102},2025,23,{"year":58,"count":104},15,[106,109,112,114,115,118,120,123,124,127,129,131,134,136,138,140,142,144,146,148,151,153,155,157,159],{"name":107,"count":108},"Utrecht University",40,{"name":110,"count":111},"Radboud University Nijmegen",24,{"name":113,"count":93},"Leiden University",{"name":20,"count":93},{"name":116,"count":117},"Vrije Universiteit Amsterdam",20,{"name":119,"count":104},"Eindhoven University of Technology",{"name":121,"count":122},"University Medical Center Groningen",13,{"name":11,"count":54},{"name":125,"count":126},"Amsterdam Neuroscience",6,{"name":128,"count":126},"Erasmus MC",{"name":130,"count":126},"University Medical Center Utrecht",{"name":132,"count":133},"Netherlands Institute for Neuroscience",5,{"name":135,"count":133},"University of Twente",{"name":137,"count":72},"Delft University of Technology",{"name":139,"count":72},"Institute for Atomic and Molecular Physics",{"name":141,"count":72},"Leiden University Medical Center",{"name":143,"count":72},"Wageningen University & Research",{"name":145,"count":69},"Broad Institute",{"name":147,"count":69},"The Netherlands Cancer Institute",{"name":149,"count":150},"Academic Medical Center",2,{"name":152,"count":150},"Amsterdam UMC Location University of Amsterdam",{"name":154,"count":150},"Maastricht University",{"name":156,"count":150},"Oncode Institute",{"name":158,"count":150},"Radboud University Medical Center",{"name":160,"count":150},"Tilburg University",[162,164,167,168,169,171,172,174,176,178,180,182,184,186,188,190,192,194],{"name":12,"count":163},234,{"name":165,"count":166},"US",17,{"name":52,"count":133},{"name":34,"count":72},{"name":170,"count":69},"CH",{"name":27,"count":69},{"name":173,"count":150},"CA",{"name":175,"count":150},"ZA",{"name":177,"count":62},"AT",{"name":179,"count":62},"AU",{"name":181,"count":62},"BE",{"name":183,"count":62},"BR",{"name":185,"count":62},"CN",{"name":187,"count":62},"CZ",{"name":189,"count":62},"IE",{"name":191,"count":62},"QA",{"name":193,"count":62},"RU",{"name":195,"count":62},"TH"]