[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-nwo-vici-2019":3,"awarded-stats-nwo-vici":66},{"awarded":4,"total":65},[5,16,23,29,35,41,47,53,58],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-639-033-514-jan-draisma-","Nederlandse Organisatie voor Wetenschappelijk Onderzoek","NWO Vici","The monic rank","Emanuele Ventura","University of Bern","CH",2019,null,"We introduce the \u003Citalic>monic rank\u003C\u002Fitalic> of a vector relative to an affine-hyperplane section of an irreducible Zariski-closed affine cone \u003Cinline-formula content-type=\"math\u002Fmathml\"> \u003Cmml:math xmlns:mml=\"http:\u002F\u002Fwww.w3.org\u002F1998\u002FMath\u002FMathML\" alttext=\"upper X\"> \u003Cmml:semantics> \u003Cmml:mi>X\u003C\u002Fmml:mi> \u003Cmml:annotation encoding=\"application\u002Fx-tex\">X\u003C\u002Fmml:annotation> \u003C\u002Fmml:semantics> \u003C\u002Fmml:math> \u003C\u002Finline-formula> . We show that the monic rank is finite and greater than or equal to the usual \u003Cinline-form",{"id":17,"funder":7,"programme":8,"title":18,"piName":19,"institution":20,"country":21,"year":13,"amount":14,"abstract":22},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-680-47-621","Perfect Absorption and Phase Singularities in Plasmon Antenna Array Etalons","A. Femius Koenderink","Institute for Atomic and Molecular Physics","NL","We present an interferometrically resolved study of the amplitude and phase response of plasmon array etalons composed of a reflective surface with in front of it a metasurface of resonant plasmonic dipole antennas. We find that above a minimum antenna oscillator strength (set by antenna size and density), such structures show conditions of perfect absorption. Contrary to earlier findings on perfect absorption, we find that these singular points unavoidably come in pairs, and are associated with",{"id":24,"funder":7,"programme":8,"title":25,"piName":26,"institution":27,"country":21,"year":13,"amount":14,"abstract":28},"openalex-nederlandse-organisatie-voor-wetenschapp-award-0161-vici-170-152","Placebo and Nocebo Effects Across Symptoms: From Pain to Fatigue, Dyspnea, Nausea, and Itch","Fabian Wolters","Leiden University","Placebo and nocebo effects are, respectively, the helpful and harmful treatment effects that do not arise from active treatment components. These effects have thus far been researched most often in pain. It is not yet clear to what extent these findings from pain can be generalized to other somatic symptoms. This review investigates placebo and nocebo effects in four other highly prevalent symptoms: dyspnea, fatigue, nausea, and itch. The role of learning mechanisms (verbal suggestions, conditio",{"id":30,"funder":7,"programme":8,"title":31,"piName":32,"institution":33,"country":21,"year":13,"amount":14,"abstract":34},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vici-453-13-006","Evaluation of a global ensemble flood prediction system in Peru","Konstantinos Bischiniotis","Vrije Universiteit Amsterdam","Flood early warning systems play a more substantial role in risk mitigation than ever before. Hydrological forecasts, which are an essential part of these systems, are used to trigger action against floods around the world. This research presents an evaluation framework, where the skills of the Global Flood Awareness System (GloFAS) are assessed in Peru for the years 2009–2015. Simulated GloFAS discharges are compared against observed ones for 10 river gauges. Forecasts skills are assessed from ",{"id":36,"funder":7,"programme":8,"title":37,"piName":38,"institution":39,"country":21,"year":13,"amount":14,"abstract":40},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-91814643","TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth\u002Fdifferentiation and breast cancer development","Lisette M. Cornelissen","The Netherlands Cancer Institute","have been reported. Here, we used in vitro and in vivo loss-of-function approaches to dissect the role of TRPS1 in mammary gland development and invasive lobular breast carcinoma, which is hallmarked by functional loss of E-cadherin. We show that TRPS1 is essential in mammary epithelial cells, since TRPS1-mediated suppression of interferon signaling promotes in vitro proliferation and lactogenic differentiation. Similarly, TRPS1 expression is indispensable for proliferation of mammary organoids ",{"id":42,"funder":7,"programme":8,"title":43,"piName":44,"institution":45,"country":21,"year":13,"amount":14,"abstract":46},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-grant-91814655","Early Recurrence in Completely Resected IIIB and IIIC Melanoma Warrants Restaging Prior to Adjuvant Therapy","Martine Bloemendal","Radboud University Nijmegen","PURPOSE: To evaluate the results of restaging completely resected stage IIIB\u002FC melanoma prior to start of adjuvant therapy. PATIENTS AND METHODS: One hundred twenty patients with stage IIIB or IIIC (AJCC 2009) melanoma who underwent complete surgical resection were screened for inclusion in our trial investigating adjuvant dendritic cell therapy (NCT02993315). All patients underwent imaging to exclude local relapse or metastasis before entering the trial. The frequency of recurrent disease withi",{"id":48,"funder":7,"programme":8,"title":49,"piName":50,"institution":51,"country":12,"year":13,"amount":14,"abstract":52},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-865-12-005-to-r-r","ARMC9 and TOGARAM1 define a Joubert syndrome-associated protein module that regulates axonemal post-translational modifications and cilium stability","Ruxandra Bachmann‐Gagescu","University of Zurich","Abstract Joubert syndrome (JBTS) is a recessive neurodevelopmental ciliopathy, characterized by a pathognomonic hindbrain malformation. All known JBTS-genes encode proteins involved in the structure or function of primary cilia, ubiquitous antenna-like organelles essential for cellular signal transduction. Here, we use the recently identified JBTS-associated protein ARMC9 in tandem-affinity purification and yeast two-hybrid screens to identify a novel ciliary module composed of ARMC9-TOGARAM1-CC",{"id":54,"funder":7,"programme":8,"title":55,"piName":56,"institution":33,"country":21,"year":13,"amount":14,"abstract":57},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-140-657-vici-","The human cytomegalovirus-encoded G protein–coupled receptor UL33 exhibits oncomodulatory properties","Martine J. Smit","tumor models, including an orthotopic glioblastoma xenograft model. UL33-mediated signaling was similar to that stimulated by US28; however, UL33-induced tumor growth was delayed. Additionally, the spatiotemporal expression of the two receptors only partially overlapped in HCMV-infected glioblastoma cells. In conclusion, our results unveil that UL33 has broad signaling capacity and provide mechanistic insight into its functional effects. UL33, like US28, exhibits oncomodulatory properties, elici",{"id":59,"funder":7,"programme":8,"title":60,"piName":61,"institution":62,"country":63,"year":13,"amount":14,"abstract":64},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vici-016-140-316-13710-to-maarten-kleinhans","Interaction between lateral sorting in river bends and vertical sorting in dunes","Anne Baar","University of Hull","GB","Abstract Sediment is sorted in river bends under the influence of gravity that pulls the heavier grains downslope and secondary flow that drags the finer grains upslope. Furthermore, when dunes are present, sediment is also sorted vertically at the dune lee side. However, sorting functions are poorly defined, since the relation to transverse bed slope and the interaction between lateral and vertical sorting is not yet understood for lack of data under controlled conditions. The objective of this",9,{"programme":8,"total":67,"withPiName":67,"firstYear":68,"lastYear":69,"countryCount":70,"perYear":71,"topInstitutions":116,"topCountries":169},296,2008,2026,18,[72,74,76,78,81,84,87,90,93,96,97,99,102,105,108,111,114],{"year":68,"count":73},1,{"year":75,"count":73},2011,{"year":77,"count":73},2012,{"year":79,"count":80},2013,3,{"year":82,"count":83},2014,4,{"year":85,"count":86},2015,7,{"year":88,"count":89},2016,14,{"year":91,"count":92},2017,44,{"year":94,"count":95},2018,65,{"year":13,"count":65},{"year":98,"count":70},2020,{"year":100,"count":101},2021,16,{"year":103,"count":104},2022,22,{"year":106,"count":107},2023,27,{"year":109,"count":110},2024,26,{"year":112,"count":113},2025,23,{"year":69,"count":115},15,[117,120,122,123,125,127,129,132,134,137,139,141,144,146,148,149,151,153,155,156,159,161,163,165,167],{"name":118,"count":119},"Utrecht University",40,{"name":45,"count":121},24,{"name":27,"count":104},{"name":124,"count":104},"University of Amsterdam",{"name":33,"count":126},20,{"name":128,"count":115},"Eindhoven University of Technology",{"name":130,"count":131},"University Medical Center Groningen",13,{"name":133,"count":86},"University of Groningen",{"name":135,"count":136},"Amsterdam Neuroscience",6,{"name":138,"count":136},"Erasmus MC",{"name":140,"count":136},"University Medical Center Utrecht",{"name":142,"count":143},"Netherlands Institute for Neuroscience",5,{"name":145,"count":143},"University of Twente",{"name":147,"count":83},"Delft University of Technology",{"name":20,"count":83},{"name":150,"count":83},"Leiden University Medical Center",{"name":152,"count":83},"Wageningen University & Research",{"name":154,"count":80},"Broad Institute",{"name":39,"count":80},{"name":157,"count":158},"Academic Medical Center",2,{"name":160,"count":158},"Amsterdam UMC Location University of Amsterdam",{"name":162,"count":158},"Maastricht University",{"name":164,"count":158},"Oncode Institute",{"name":166,"count":158},"Radboud University Medical Center",{"name":168,"count":158},"Tilburg University",[170,172,175,177,178,179,181,183,185,187,189,191,193,195,197,199,201,203],{"name":21,"count":171},234,{"name":173,"count":174},"US",17,{"name":176,"count":143},"DE",{"name":63,"count":83},{"name":12,"count":80},{"name":180,"count":80},"IT",{"name":182,"count":158},"CA",{"name":184,"count":158},"ZA",{"name":186,"count":73},"AT",{"name":188,"count":73},"AU",{"name":190,"count":73},"BE",{"name":192,"count":73},"BR",{"name":194,"count":73},"CN",{"name":196,"count":73},"CZ",{"name":198,"count":73},"IE",{"name":200,"count":73},"QA",{"name":202,"count":73},"RU",{"name":204,"count":73},"TH"]