[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-nwo-vidi-2020":3,"awarded-stats-nwo-vidi":236},{"awarded":4,"total":235},[5,16,23,30,35,41,48,54,61,67,72,79,84,86,92,99,105,111,117,123,130,136,142,148,153,159,165,171,176,182,188,193,198,204,209,215,221,225,230],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-864-13-013","Nederlandse Organisatie voor Wetenschappelijk Onderzoek","NWO Vidi","The role of the gut microbiome in graft fibrosis after pediatric liver transplantation","Henkjan J. Verkade","University Medical Center Groningen","NL",2020,null,"Liver transplantation (LT) is a life-saving option for children with end-stage liver disease. However, about 50% of patients develop graft fibrosis in 1 year after LT, with normal liver function. Graft fibrosis may progress to cirrhosis, resulting in graft dysfunction and ultimately the need for re-transplantation. Previous studies have identified various risk factors for the post-LT fibrogenesis, however, to date, neither of the factors seems to fully explain the cause of graft fibrosis. Recent",{"id":17,"funder":7,"programme":8,"title":18,"piName":19,"institution":20,"country":21,"year":13,"amount":14,"abstract":22},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-864-10-012","Geographic variation in baseline innate immune function does not follow variation in aridity along a tropical environmental gradient","Chima J. Nwaogu","University of Cape Town","ZA","Geographic variation in aridity determines environmental productivity patterns, including large-scale variability in pathogens, vectors and associated diseases. If disease risk decreases with increasing aridity and is matched by immune defense, we predict a decrease in innate immune function along a gradient of increasing aridity from the cool-wet forest to the hot-dry Sahel, from south to north in Nigeria. We sampled blood and measured five innate immune indices from 286 Common Bulbuls Pycnonot",{"id":24,"funder":7,"programme":8,"title":25,"piName":26,"institution":27,"country":28,"year":13,"amount":14,"abstract":29},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-178-023","A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns","Lincoln Stein","Ontario Institute for Cancer Research","CA","In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC\u002FTCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we train a deep learning classifier to predict cancer type based on patterns of somatic passenger mutations detected in whole genome sequencing (WGS) of 2606 tumours representing 24 common cancer type",{"id":31,"funder":7,"programme":8,"title":32,"piName":33,"institution":11,"country":12,"year":13,"amount":14,"abstract":34},"openalex-nederlandse-organisatie-voor-wetenschapp-award-917-13-350","Reverse Cardio‐Oncology: Cancer Development in Patients With Cardiovascular Disease","Rudolf A. de Boer","Dr de Boer is supported by the European Research Council (CoG 818715 and SECRETE-HF); and further by the Netherlands Heart Foundation (CVON DOSIS, grant 2014-40; CVON SHE-PREDICTS-HF, grant 2017-21; CVON RED-CVD, grant 2017-11; and CVON PREDICT2, grant 2018-30); the Innovational Research Incentives Scheme program of the Netherlands Organization for Scientific Research (NWO VIDI, grant 917.13.350); and by a grant from the leDucq Foundation (Cure Phospholamban Induced Cardiomyopathy). Dr Moslehi i",{"id":36,"funder":7,"programme":8,"title":37,"piName":38,"institution":39,"country":12,"year":13,"amount":14,"abstract":40},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-680-47-544","Dormancy‐to‐death transition in yeast spores occurs due to gradual loss of gene‐expressing ability","Théo Maire","Delft University of Technology","Dormancy is colloquially considered as extending lifespan by being still. Starved yeasts form dormant spores that wake-up (germinate) when nutrients reappear but cannot germinate (die) after some time. What sets their lifespans and how they age are open questions because what processes occur-and by how much-within each dormant spore remains unclear. With single-cell-level measurements, we discovered how dormant yeast spores age and die: spores have a quantifiable gene-expressing ability during d",{"id":42,"funder":7,"programme":8,"title":43,"piName":44,"institution":45,"country":46,"year":13,"amount":14,"abstract":47},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-no-68047512","Impact cratering in sand: comparing solid and liquid intruders","Song‐Chuan Zhao","Xi'an Jiaotong University","CN","How does the impact of a deformable droplet on a granular bed differ from that caused by a solid impactor of similar size and density? Here, we experimentally study this question and focus on the effect of intruder deformability on the crater shape. For comparable impact energies, we show that the crater diameter is larger for droplets than for solid intruders but that the impact of the latter results in deeper craters. Interestingly, for initially dense beds of packing fractions larger than 0.5",{"id":49,"funder":7,"programme":8,"title":50,"piName":51,"institution":52,"country":12,"year":13,"amount":14,"abstract":53},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-grant-024-001-003-and-vi-vidi-195-152","Instagram Use and the Well-Being of Adolescents: Using Deep Learning to Link Social Scientific Self-reports with Instagram Data Download Packages","Laura Boeschoten","Utrecht University","Since the introduction of social media platforms, researchers have investigated how the use of such media affects adolescents? well-being. Thus far, findings have been inconsistent [1, 2, 3]. The aim of our interdisciplinary project is to provide a more thorough understanding of these inconsistencies by investigating who benefits from social media use, who does not and why it is beneficial for one yet harmful for another [1]. In this presentation, we explain our approach to combining social scie",{"id":55,"funder":7,"programme":8,"title":56,"piName":57,"institution":58,"country":59,"year":13,"amount":14,"abstract":60},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-016-vidi-185-046","The Female Mortality Advantage in the Seventeenth‐Century Rural Low Countries","Daniel R. Curtis","EuroSpine","CH","ABSTRACT Data from famines from the nineteenth century onward suggest that women hold a mortality advantage during times of acute malnutrition, while modern laboratory research suggests that women are more resilient to most pathogens causing epidemic diseases. There is, however, a paucity of sex‐disaggregated mortality data for the period prior to the Industrial Revolution to test this view across a broader span of history. We offer a newly compiled database of adult burial information for 293 r",{"id":62,"funder":7,"programme":8,"title":63,"piName":64,"institution":65,"country":12,"year":13,"amount":14,"abstract":66},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-projectruimte-vrij-programma-680-92-18-04","Comparing nonlinear optomechanical coupling in membrane-in-the-middle and single-cavity systems","Ewold Verhagen","Institute for Atomic and Molecular Physics","Abstract In cavity optomechanics, nonlinear interactions between an optical field and a mechanical resonator mode enable a variety of unique effects in classical and quantum measurement and information processing. Here, we describe nonlinear optomechanical coupling in the membrane-in-the-middle (MIM) system in a way that allows direct comparison to the intrinsic optomechanical nonlinearity in a standard, single-cavity optomechanical system. We find that the enhancement of nonlinear optomechanica",{"id":68,"funder":7,"programme":8,"title":69,"piName":70,"institution":11,"country":12,"year":13,"amount":14,"abstract":71},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-723-014-001","A Photocleavable Contrast Agent for Light-Responsive MRI","Wiktor Szymański","Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents' relaxivity with the aim to increase the sensitivity, selectivity and amount of functional information obtained from this outstanding whole-body medical imaging technique. This approach requires the development of molecular contrast agents that show high relaxivity and strong",{"id":73,"funder":7,"programme":8,"title":74,"piName":75,"institution":76,"country":77,"year":13,"amount":14,"abstract":78},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-639-042-729","ClG 0217+70: A massive merging galaxy cluster with a large radio halo and relics","Shea Brown","University of Iowa","US","We present an analysis of archival Chandra data of the merging galaxy cluster ClG 0217+70. The Fe \u003Cns0:sc>XXV\u003C\u002Fns0:sc> Heα X-ray emission line is clearly visible in the 25 ks observation, allowing a precise determination of the redshift of the cluster as z = 0.180 ± 0.006. We measure kT500 = 8.3 ± 0.4 keV and estimate M500 = (1.06 ± 0.11) × 1015 M⊙ based on existing scaling relations. Correcting both the radio and X-ray luminosities with the revised redshift reported here, which is much larger t",{"id":80,"funder":7,"programme":8,"title":81,"piName":82,"institution":39,"country":12,"year":13,"amount":14,"abstract":83},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-178047","Human-like driving behaviour emerges from a risk-based driver model","Sarvesh Kolekar","Current driving behaviour models are designed for specific scenarios, such as curve driving, obstacle avoidance, car-following, or overtaking. However, humans can drive in diverse scenarios. Can we find an underlying principle from which driving behaviour in different scenarios emerges? We propose the Driver's Risk Field (DRF), a two-dimensional field that represents the driver's belief about the probability of an event occurring. The DRF, when multiplied with the consequence of the event, provi",{"id":85,"funder":7,"programme":8,"title":81,"piName":82,"institution":39,"country":12,"year":13,"amount":14,"abstract":83},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-14127",{"id":87,"funder":7,"programme":8,"title":88,"piName":89,"institution":90,"country":12,"year":13,"amount":14,"abstract":91},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-grant-no-016-161-321","Shrinking body sizes in response to warming: explanations for the temperature–size rule with special emphasis on the role of oxygen","Wilco C. E. P. Verberk","Radboud University Nijmegen","Body size is central to ecology at levels ranging from organismal fecundity to the functioning of communities and ecosystems. Understanding temperature-induced variations in body size is therefore of fundamental and applied interest, yet thermal responses of body size remain poorly understood. Temperature-size (T-S) responses tend to be negative (e.g. smaller body size at maturity when reared under warmer conditions), which has been termed the temperature-size rule (TSR). Explanations emphasize ",{"id":93,"funder":7,"programme":8,"title":94,"piName":95,"institution":96,"country":97,"year":13,"amount":14,"abstract":98},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-project-no-680-47-543-","On the topological immunity of corner states in two-dimensional crystalline insulators","Guido van Miert","University of Salerno","IT","Abstract A higher-order topological insulator (HOTI) in two dimensions is an insulator without metallic edge states but with robust zero-dimensional topological boundary modes localized at its corners. Yet, these corner modes do not carry a clear signature of their topology as they lack the anomalous nature of helical or chiral boundary states. Here, we demonstrate using immunity tests that the corner modes found in the breathing kagome lattice represent a prime example of a mistaken identity. C",{"id":100,"funder":7,"programme":8,"title":101,"piName":102,"institution":103,"country":12,"year":13,"amount":14,"abstract":104},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-award-680-47-550","Plasmon-driven synthesis of individual metal@semiconductor core@shell nanoparticles","Rifat Kamarudheen","Dutch Institute for Fundamental Energy Research","Abstract Most syntheses of advanced materials require accurate control of the operating temperature. Plasmon resonances in metal nanoparticles generate nanoscale temperature gradients at their surface that can be exploited to control the growth of functional nanomaterials, including bimetallic and core@shell particles. However, in typical ensemble plasmonic experiments these local gradients vanish due to collective heating effects. Here, we demonstrate how localized plasmonic photothermal effect",{"id":106,"funder":7,"programme":8,"title":107,"piName":108,"institution":109,"country":12,"year":13,"amount":14,"abstract":110},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-723-016-001","Cephalopod‐Inspired High Dynamic Range Mechano‐Imaging in Polymeric Materials","Joris Sprakel","Dutch Polymer Institute","Abstract Cephalopods, such as squid, cuttlefish, and octopuses, use an array of responsive absorptive and photonic dermal structures to achieve rapid and reversible color changes for spectacular camouflage and signaling displays. Challenges remain in designing synthetic soft materials with similar multiple and dynamic responsivity for the development of optical sensors for the sensitive detection of mechanical stresses and strains. Here, a high dynamic range mechano‐imaging (HDR‐MI) polymeric ma",{"id":112,"funder":7,"programme":8,"title":113,"piName":114,"institution":115,"country":12,"year":13,"amount":14,"abstract":116},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-452-03-329","A multiverse analysis of early attempts to replicate memory suppression with the Think\u002FNo-think Task","Ineke Wessel","University of Groningen","= 80) were reanalysed in a similar fashion. For recall probed with studied cues (Same Probes, SP), some tests (sample 3) or all (samples 2 and 4) showed statistically significant suppression effects, whereas in sample 1, only one test showed significance. Recall probed with novel cues (Independent Probes, IP) predominantly rendered non-significant results. The absence of statistically significant IP suppression effects raises problems for inhibition theory and its implication that repression is ",{"id":118,"funder":7,"programme":8,"title":119,"piName":120,"institution":121,"country":28,"year":13,"amount":14,"abstract":122},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-864-11-015","Nitrapyrin has far reaching effects on the soil microbial community structure, composition, diversity and functions","Étienne Yergeau","Institut National de la Recherche Scientifique","Abstract Nitrapyrin is one of the most common nitrification inhibitors that are used to retain N in the ammonia form in soil to improve crop yields and quality. Whereas the inhibitory effect of nitrapyrin is supposedly specific to ammonia oxidizers, in view of the keystone role of this group in soils, nitrapyrin could have far-reaching impacts. Here, we tested the hypothesis that nitrapyrin leads to large shifts in soil microbial community structure, composition, diversity and functions, beyond ",{"id":124,"funder":7,"programme":8,"title":125,"piName":126,"institution":127,"country":128,"year":13,"amount":14,"abstract":129},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-639-032-221","Obstructions for Symplectic Lie Algebroids","Universit&","Université Libre de Bruxelles","BE","Several types of generically-nondegenerate Poisson structures can be effectively studied as symplectic structures on naturally associated Lie algebroids. Relevant examples of this phenomenon include log-, elliptic, b<sup>k<\u002Fsup>-, scattering and elliptic-log Poisson structures. In this paper we discuss topological obstructions to the existence of such Poisson structures, obtained through the characteristic classes of their associated symplectic Lie algebroids. In particular we obtain",{"id":131,"funder":7,"programme":8,"title":132,"piName":133,"institution":134,"country":12,"year":13,"amount":14,"abstract":135},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-nwo-vidi-grant-452-17-011-","The effect of social media on well-being differs from adolescent to adolescent","Ine Beyens","Amsterdam University of Applied Sciences","The question whether social media use benefits or undermines adolescents' well-being is an important societal concern. Previous empirical studies have mostly established across-the-board effects among (sub)populations of adolescents. As a result, it is still an open question whether the effects are unique for each individual adolescent. We sampled adolescents' experiences six times per day for one week to quantify differences in their susceptibility to the effects of social media on their moment",{"id":137,"funder":7,"programme":8,"title":138,"piName":139,"institution":140,"country":77,"year":13,"amount":14,"abstract":141},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-723-016-002","Wasserstein metric for improved quantum machine learning with adjacency matrix representations","O. Anatole von Lilienfeld","University of California, Los Angeles","We study the Wasserstein metric to measure distances between molecules represented by the atom index dependent adjacency 'Coulomb' matrix, used in kernel ridge regression based supervised learning. Resulting machine learning models of quantum properties, a.k.a. quantum machine learning models exhibit improved training efficiency and result in smoother predictions of energies related to molecular distortions. We first illustrate smoothness for the continuous extraction of an atom from some organi",{"id":143,"funder":7,"programme":8,"title":144,"piName":145,"institution":146,"country":77,"year":13,"amount":14,"abstract":147},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-917-113-349","Anti‐migraine Calcitonin Gene–Related Peptide Receptor Antagonists Worsen Cerebral Ischemic Outcome in Mice","Cenk Ayata","Harvard University","OBJECTIVE: Calcitonin gene-related peptide (CGRP) pathway inhibitors are emerging treatments for migraine. CGRP-mediated vasodilation is, however, a critical rescue mechanism in ischemia. We, therefore, investigated whether gepants, small molecule CGRP receptor antagonists, worsen cerebral ischemia. METHODS: Middle cerebral artery was occluded for 12 to 60 minutes in mice. We compared infarct risk and volumes, collateral flow, and neurological deficits after pretreatment with olcegepant (single ",{"id":149,"funder":7,"programme":8,"title":150,"piName":151,"institution":90,"country":12,"year":13,"amount":14,"abstract":152},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-13455","Pre-Clinical Evaluation of Biological Bone Substitute Materials for Application in Highly Loaded Skeletal Sites","John A. Jansen","The development of bone substitute materials (BSMs) intended for load-bearing bone defects is highly complicated, as biological and mechanical requirements are often contradictory. In recent years, biological BSMs have been developed which allow for a more efficient integration of the material with the surrounding osseous environment and, hence, a higher mechanical stability of the treated defect. However, while these materials are promising, they are still far from ideal. Consequently, extensiv",{"id":154,"funder":7,"programme":8,"title":155,"piName":156,"institution":157,"country":12,"year":13,"amount":14,"abstract":158},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-grant-91714336","Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating","Rupamanjari Majumder","Leiden University Medical Center","Homeostatic regulation protects organisms against hazardous physiological changes. However, such regulation is limited in certain organs and associated biological processes. For example, the heart fails to self-restore its normal electrical activity once disturbed, as with sustained arrhythmias. Here we present proof-of-concept of a biological self-restoring system that allows automatic detection and correction of such abnormal excitation rhythms. For the heart, its realization involves the inte",{"id":160,"funder":7,"programme":8,"title":161,"piName":162,"institution":163,"country":12,"year":13,"amount":14,"abstract":164},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-452-14-002","Killing them softly? Two complementary studies on visibility and framing of new parties in the news","Joost van Spanje","University of Amsterdam","Democratic systems need some degree of openness to new ideas and to new competitors. New parties depend on news media to survive. Which new parties receive news media coverage, and what kind of coverage do these parties receive? This article brings in the media into the literature of new parties. Based on two original datasets compiled for this study, the news media coverage of dozens of parties in a variety of offline and online news media sources since 1947 is analyzed to address the two resea",{"id":166,"funder":7,"programme":8,"title":167,"piName":168,"institution":169,"country":12,"year":13,"amount":14,"abstract":170},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-917-13-338","Murine iNKT cells are depleted by liver damage via activation of P2RX7","Regina Stark","Sanquin","Invariant natural killer T cells (iNKT) constitute up to 50% of liver lymphocytes and contribute to immunosurveillance as well as pathogenesis of the liver. Systemic activation of iNKT cells induces acute immune-mediated liver injury. However, how tissue damage events regulate iNKT cell function and homeostasis remains unclear. We found that specifically tissue-resident iNKT cells in liver and spleen express the tissue-damage receptor P2RX7 and the P2RX7-activating ectoenzyme ARTC2. P2RX7 expres",{"id":172,"funder":7,"programme":8,"title":173,"piName":174,"institution":115,"country":12,"year":13,"amount":14,"abstract":175},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-016-126-307","Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation","Tim Koopmans","Abstract Asthma is a heterogeneous disease characterized by chronic inflammation and structural changes in the airways. The airway smooth muscle (ASM) is responsible for airway narrowing and an important source of inflammatory mediators. We and others have previously shown that WNT5A mRNA and protein expression is higher in the ASM of asthmatics compared to healthy controls. Here, we aimed to characterize the functional role of (smooth muscle-derived) WNT5A in asthma. We generated a tet-ON smoot",{"id":177,"funder":7,"programme":8,"title":178,"piName":179,"institution":180,"country":12,"year":13,"amount":14,"abstract":181},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-june-2013","The Predictive Value of Glomerular Filtration Rate-Based Scaling of Pediatric Clearance and Doses for Drugs Eliminated by Glomerular Filtration with Varying Protein-Binding Properties","Sînziana Cristea","Centre for Human Drug Research","INTRODUCTION: For drugs eliminated by glomerular filtration (GF), clearance (CL) is determined by GF rate (GFR) and the unbound fraction of the drug. When predicting CL of GF-eliminated drugs in children, instead of physiologically based pharmacokinetic (PBPK) methods that consider changes in both GFR and protein binding, empiric bodyweight-based methods are often used. In this article, we explore the predictive value of scaling using a GFR function, and compare the results with linear and allom",{"id":183,"funder":7,"programme":8,"title":184,"piName":185,"institution":186,"country":77,"year":13,"amount":14,"abstract":187},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-grant-016-171-047-","Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes","Bana Jabrì","University of Chicago","The respective effects of tissue alarmins interleukin (IL)-15 and interferon beta (IFNβ), and IL-21 produced by T cells on the reprogramming of cytotoxic T lymphocytes (CTLs) that cause tissue destruction in celiac disease is poorly understood. Transcriptomic and epigenetic profiling of primary intestinal CTLs showed massive and distinct temporal transcriptional changes in response to tissue alarmins, while the impact of IL-21 was limited. Only anti-viral pathways were induced in response to all",{"id":189,"funder":7,"programme":8,"title":190,"piName":191,"institution":90,"country":12,"year":13,"amount":14,"abstract":192},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-723-015-001","Leveraging synthetic particles for communication: from passive to active systems","Daniela A. Wilson","Communication is one of the most remarkable behaviors in the living world. It is an important prerequisite for building an artificial cell which can be considered as alive. Achieving complex communicative behaviors leveraging synthetic particles will likely fill the gap between artificial vesicles and natural counterpart of cells and allow for the discovery of new therapies in medicine. In this review, we highlight recent endeavors for constructing communication with synthetic particles by revea",{"id":194,"funder":7,"programme":8,"title":195,"piName":196,"institution":197,"country":59,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-178-056","Faculty Opinions recommendation of Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.","Matthew Horton","University of Zurich",{"id":199,"funder":7,"programme":8,"title":200,"piName":201,"institution":202,"country":46,"year":13,"amount":14,"abstract":203},"openalex-nederlandse-organisatie-voor-wetenschapp-award-v-i-vidi-192-045","“Nano-garden cultivation” for electrocatalysis: controlled synthesis of Nature-inspired hierarchical nanostructures","Ning Yan","Wuhan University","The rational coupling of hydrothermal and electrodeposition approaches enables controlled synthesis of various CoP Nature-inspired nanostructures with distinct electrocatalytic performance.",{"id":205,"funder":7,"programme":8,"title":206,"piName":207,"institution":52,"country":12,"year":13,"amount":14,"abstract":208},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-019","ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability","Ginny G. Farı́as","ABSTRACT Neuronal function relies on careful coordination of organelle organization and transport. Kinesin-1 mediates transport of the ER and lysosomes into the axon and it is increasingly recognized that contacts between the ER and lysosomes influence organelle organization. However, it is unclear how organelle organization, inter-organelle communication and transport are linked and how this contributes to local organelle availability in neurons. Here, we show that somatic ER tubules are requir",{"id":210,"funder":7,"programme":8,"title":211,"piName":212,"institution":213,"country":214,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-049","If Sick-Leave Becomes More Costly, Will I Go Back to Work? Could it Be Too Soon?","Olivier Marie","London School of Economics and Political Science","GB",{"id":216,"funder":7,"programme":8,"title":217,"piName":218,"institution":219,"country":12,"year":13,"amount":14,"abstract":220},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-no-016-126-327","The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management","Ronit Shiri‐Sverdlov","Maastricht University","Cathepsins are the most abundant lysosomal proteases that are mainly found in acidic endo\u002Flysosomal compartments where they play a vital role in intracellular protein degradation, energy metabolism, and immune responses among a host of other functions. The discovery that cathepsins are secreted and remain functionally active outside of the lysosome has caused a paradigm shift. Contemporary research has unraveled many versatile functions of cathepsins in extralysosomal locations including cytosol",{"id":222,"funder":7,"programme":8,"title":223,"piName":224,"institution":52,"country":12,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-173","Book review","Giuseppe Feola",{"id":226,"funder":7,"programme":8,"title":227,"piName":228,"institution":115,"country":12,"year":13,"amount":14,"abstract":229},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-639-032-733","A distributional solution framework for linear hyperbolic PDEs coupled to switched DAEs","Stephan Trenn","Abstract A distributional solution framework is developed for systems consisting of linear hyperbolic partial differential equations and switched differential-algebraic equations (DAEs) which are coupled via boundary conditions. The unique solvability is then characterize in terms of a switched delay DAE. The theory is illustrated with an example of electric power lines modelled by the telegraph equations which are coupled via a switching transformer where simulations confirm the predicted impul",{"id":231,"funder":7,"programme":8,"title":232,"piName":233,"institution":90,"country":12,"year":13,"amount":14,"abstract":234},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-639-032-614","Single‐conflict colouring","Ross J. Kang","Abstract Given a multigraph, suppose that each vertex is given a local assignment of colours to its incident edges. We are interested in whether there is a choice of one local colour per vertex such that no edge has both of its local colours chosen. The least for which this is always possible given any set of local assignments we call the single‐conflict chromatic number of the graph. This parameter is closely related to separation choosability and adaptable choosability. We show that single‐con",39,{"programme":8,"total":237,"withPiName":237,"firstYear":238,"lastYear":239,"countryCount":240,"perYear":241,"topInstitutions":291,"topCountries":346},788,2008,2026,33,[242,244,247,249,252,255,258,261,264,267,270,273,274,277,280,283,286,289],{"year":238,"count":243},1,{"year":245,"count":246},2009,2,{"year":248,"count":243},2011,{"year":250,"count":251},2012,3,{"year":253,"count":254},2013,5,{"year":256,"count":257},2014,6,{"year":259,"count":260},2015,15,{"year":262,"count":263},2016,41,{"year":265,"count":266},2017,58,{"year":268,"count":269},2018,114,{"year":271,"count":272},2019,28,{"year":13,"count":235},{"year":275,"count":276},2021,34,{"year":278,"count":279},2022,37,{"year":281,"count":282},2023,66,{"year":284,"count":285},2024,116,{"year":287,"count":288},2025,133,{"year":239,"count":290},89,[292,294,296,298,300,302,303,306,308,311,313,314,317,320,323,325,327,330,331,334,336,337,339,341,343],{"name":52,"count":293},63,{"name":90,"count":295},60,{"name":115,"count":297},52,{"name":163,"count":299},40,{"name":301,"count":279},"Leiden University",{"name":39,"count":272},{"name":304,"count":305},"Wageningen University & Research",25,{"name":11,"count":307},19,{"name":309,"count":310},"Eindhoven University of Technology",17,{"name":312,"count":310},"Erasmus MC",{"name":219,"count":310},{"name":315,"count":316},"Erasmus University Rotterdam",16,{"name":318,"count":319},"Vrije Universiteit Amsterdam",14,{"name":321,"count":322},"Amsterdam Neuroscience",12,{"name":324,"count":322},"University Medical Center Utrecht",{"name":157,"count":326},11,{"name":328,"count":329},"Centre National de la Recherche Scientifique",8,{"name":65,"count":329},{"name":332,"count":333},"Netherlands Institute of Ecology",7,{"name":335,"count":333},"University of Twente",{"name":134,"count":257},{"name":338,"count":257},"Netherlands Institute for Neuroscience",{"name":340,"count":257},"Tilburg University",{"name":342,"count":254},"Royal Netherlands Institute for Sea Research",{"name":344,"count":345},"Amsterdam University Medical Centers",4,[347,349,352,354,356,359,361,362,363,364,366,367,369,371,373,375,377,379,381,383,385,386,388,390,392],{"name":12,"count":348},558,{"name":350,"count":351},"DE",30,{"name":77,"count":353},27,{"name":214,"count":355},21,{"name":357,"count":358},"FR",13,{"name":128,"count":360},9,{"name":59,"count":360},{"name":97,"count":329},{"name":46,"count":333},{"name":365,"count":254},"AU",{"name":28,"count":254},{"name":368,"count":254},"DK",{"name":370,"count":254},"ES",{"name":372,"count":345},"AT",{"name":374,"count":345},"BR",{"name":376,"count":251},"IE",{"name":378,"count":246},"HU",{"name":380,"count":246},"PL",{"name":382,"count":246},"SE",{"name":384,"count":246},"SG",{"name":21,"count":246},{"name":387,"count":243},"AE",{"name":389,"count":243},"AR",{"name":391,"count":243},"BD",{"name":393,"count":243},"CL"]