[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"awarded-nwo-vidi-2025":3,"awarded-stats-nwo-vidi":731},{"awarded":4,"total":730},[5,16,21,28,34,39,44,50,57,63,70,77,83,88,94,99,105,110,117,124,130,135,140,146,152,159,161,167,170,176,181,183,188,194,200,206,212,217,222,227,234,240,246,252,257,263,268,273,278,284,289,296,301,306,312,317,322,327,331,336,342,347,352,358,365,370,376,382,387,393,399,404,409,415,417,422,428,435,441,447,453,458,463,468,473,479,484,491,496,501,506,511,516,522,527,532,537,543,548,553,559,564,569,571,576,581,587,592,597,602,607,612,617,622,627,633,638,643,649,655,660,665,671,676,681,686,691,696,701,706,711,718,725],{"id":6,"funder":7,"programme":8,"title":9,"piName":10,"institution":11,"country":12,"year":13,"amount":14,"abstract":15},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-233-205","Nederlandse Organisatie voor Wetenschappelijk Onderzoek","NWO Vidi","The persistent Laplacian of non-branching complexes","Rui Dong","Vrije Universiteit Amsterdam","NL",2025,null,"Non-branching matrices are real matrices with entries in $ \\{-1, 0, 1\\} $, where each row contains at most two non-zero entries. Such matrices naturally arise in the study of Laplacians of pseudomanifolds and cubical complexes. We show that a basis for the kernel of a non-branching matrix can be computed in near-linear time. Specifically, the basis has the special property that the supports of all the column vectors in it are disjoint with each other. Building on this result, we show that the up",{"id":17,"funder":7,"programme":8,"title":18,"piName":19,"institution":20,"country":12,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-099","Generic Security of the Ascon Mode: On the Power of Key Blinding","Bart Mennink","Radboud University Nijmegen",{"id":22,"funder":7,"programme":8,"title":23,"piName":24,"institution":25,"country":26,"year":13,"amount":14,"abstract":27},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-008","Lactate controls cancer stemness and plasticity through epigenetic regulation","Maria J. Rodríguez Colman","Heidelberg University","DE","Tumors arise from uncontrolled cell proliferation driven by mutations in genes that regulate stem cell renewal and differentiation. Intestinal tumors, however, retain some hierarchical organization, maintaining both cancer stem cells (CSCs) and cancer differentiated cells (CDCs). This heterogeneity, coupled with cellular plasticity enabling CDCs to revert to CSCs, contributes to therapy resistance and relapse. Using genetically encoded fluorescent reporters in human tumor organoids, combined wit",{"id":29,"funder":7,"programme":8,"title":30,"piName":31,"institution":32,"country":12,"year":13,"amount":14,"abstract":33},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-195-020","To Oppose or Not to Oppose? Strategies of Opposition Parties’ Parliamentary Support for Government Legislation","Rick L. van Well","Leiden University","Abstract While opposition parties are expected to challenge the government and present alternatives, they often support government legislation. Synthesizing key theoretical explanations, this study examines how opposition parties weigh their goals of winning the next elections, joining or replacing the government and influencing policy. It is hypothesized that opposition parties are more likely to oppose bills when they see chances for boosting their electoral prospects or an early government al",{"id":35,"funder":7,"programme":8,"title":36,"piName":37,"institution":14,"country":14,"year":13,"amount":14,"abstract":38},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-015","Kodaira dimension of moduli spaces of hyperkähler varieties","Laure Flapan","We study the Kodaira dimension of moduli spaces of polarized hyperkähler varieties deformation equivalent to the Hilbert scheme of points on a K3 surface or to O'Grady's ten-dimensional variety.This question was studied by Gritsenko-Hulek-Sankaran in the cases of K3 [2] -and OG10-type when the divisibility of the polarization is 1.We generalize their results to higher dimension and divisibility.As a main result, for almost all dimensions 2n, we provide a lower bound on the degree such that for a",{"id":40,"funder":7,"programme":8,"title":41,"piName":42,"institution":20,"country":12,"year":13,"amount":14,"abstract":43},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-project-nr-195-085","How populist citizens see the people and their place in representative democracy","Rosa Kindt","As democracy is often described as government of the people, by the people, and for the people, determining who constitutes ‘the people’ is essential for the working of democracy. Somewhat surprisingly, only populists have embraced this term as a regular part of their rhetoric. This begs the question: Who are\u002Fshould be the people who hold power and are represented? No research has yet empirically established how citizens conceptualise the people or how this relates to their representation prefer",{"id":45,"funder":7,"programme":8,"title":46,"piName":47,"institution":48,"country":12,"year":13,"amount":14,"abstract":49},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-190-6208","Language Learning as a Non-Pharmacological Intervention in Older Adults with (Past) Depression","J.G. Brouwer","University Medical Center Groningen","Background: Language learning has been proposed as a non-pharmacological intervention to promote healthy aging. This intervention has not been studied in older adults with a history of depression, who experience high prevalence of cognitive dysfunction. This small-scale study was the first to investigate the potential efficacy of language learning in older adults with (past) depression. Methods: Data on psychosocial well-being, cognitive functioning, and language outcomes were collected in ninet",{"id":51,"funder":7,"programme":8,"title":52,"piName":53,"institution":54,"country":55,"year":13,"amount":14,"abstract":56},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-020","Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail","Bertram Daum","University of Exeter","GB","While archaeal viruses show a stunning diversity of morphologies, many bear a notable resemblance to tailed bacterial phages. This raises fundamental questions: Do all tailed viruses share a common origin and do they infect their hosts in similar ways? Answering these questions requires high-resolution structural insights, yet no complete atomic models of archaeal viruses have been available. Here, we present the near-atomic resolution structure of Haloferax tailed virus 1 (HFTV1), an archaeal v",{"id":58,"funder":7,"programme":8,"title":59,"piName":60,"institution":61,"country":12,"year":13,"amount":14,"abstract":62},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vl-vidi-198-001","The role of financial scarcity in the relationship between income and health behaviors: a causal mediation analysis","Frank J. van Lenthe","Erasmus MC","BACKGROUND: Financial scarcity is an increasing problem and health behaviors may be impaired by subjective experience of stress due to financial scarcity. Financial scarcity is a stress-response to having insufficient financial means and may affect cognitive functioning. This study aimed to assess whether financial scarcity mediates the association between income and health behaviors. METHODS: We used self-reported cross-sectional data of 2379 adults from the 2021 wave of the Dutch population-ba",{"id":64,"funder":7,"programme":8,"title":65,"piName":66,"institution":67,"country":68,"year":13,"amount":14,"abstract":69},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-864-08-010","Wound-induced eyespots on butterfly wings at the intersection of immune response and pigmentation development","Patrícia Beldade","Sustainability Institute","ZA","BACKGROUND: Butterfly eyespots are striking examples of evolutionary novelty arising through the repurposing of ancestral genetic pathways, including pathways involved in wound healing. Given the activation of the immune system during wound healing and the known links between immunity and pigmentation, we hypothesized that the immune response triggered by wounding contributes to the formation of wound-induced ectopic eyespots on butterfly wings. RESULTS: We tested this hypothesis by wounding the",{"id":71,"funder":7,"programme":8,"title":72,"piName":73,"institution":74,"country":75,"year":13,"amount":14,"abstract":76},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-91717369","Startling acoustic stimuli hasten reflexive choice reaching tasks by enhancing, but not changing the timing of, express visuomotor responses","Brian D. Corneil","Western University","CA","Responding to an external stimulus takes ∼200 ms, but this can be shortened to as little as ∼120 ms with the additional presentation of a startling acoustic stimulus. This phenomenon is hypothesized to arise from the involuntary release of a prepared movement (a StartReact effect). However, a startling acoustic stimulus also expedites rapid mid-flight, reactive adjustments to unpredictably displaced targets which could not have been prepared in advance. We surmise that for such rapid visuomotor ",{"id":78,"funder":7,"programme":8,"title":79,"piName":80,"institution":81,"country":12,"year":13,"amount":14,"abstract":82},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-alw-vidi-864-13-002","Mechanistic dissection of GRHL2 and PR transcriptional co-regulation in breast cells","Renée van Amerongen","University of Amsterdam","Abstract Gene expression is controlled by complex transcriptional networks in which transcription factors and their cognate enhancer elements integrate developmental and environmental cues. The progesterone receptor (PR), a hormone-activated transcription factor, is essential for breast development and physiology, yet how it engages with the chromatin and lineage-specific cofactors remains unclear. Using an unbiased approach, we identify the epithelial transcription factor grainyhead-like 2 (GRH",{"id":84,"funder":7,"programme":8,"title":85,"piName":86,"institution":11,"country":12,"year":13,"amount":14,"abstract":87},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-068","Near optimal bounds for weak and strong spatial mixing for the anti-ferromagnetic Potts model on trees","Guus Regts","We show that the anti-ferromagnetic Potts model on trees exhibits strong spatial mixing for a near-optimal range of parameters. Our work complements recent results of Chen, Liu, Mani, and Moitra [CLMM23] who showed this to be true in the infinite temperature setting, corresponding to uniform proper colorings. We furthermore prove weak spatial mixing results complementing results in [CLMM23].",{"id":89,"funder":7,"programme":8,"title":90,"piName":91,"institution":92,"country":12,"year":13,"amount":14,"abstract":93},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-069","Fabrication and Characterization of Bimetallic Silica-Based and 3D-Printed Active Colloidal Cubes","Daniela J. Kraft","Huygens Institute for History and Culture of the Netherlands","Simulations on self-propelling active cubes reveal interesting behaviors at both the individual and the collective level, emphasizing the importance of developing experimental analogues that allow testing these theoretical predictions. The majority of experimental realizations of active colloidal cubes rely on light actuation and\u002For magnetic fields to have a persistent active mechanism and lack material versatility. Here, we propose a system of active bimetallic cubes whose propulsion mechanism ",{"id":95,"funder":7,"programme":8,"title":96,"piName":97,"institution":14,"country":14,"year":13,"amount":14,"abstract":98},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-113","Classifying merger stages with adaptive deep learning and cosmological hydrodynamical simulations","Mike Walmsley","Aims. Hierarchical merging of galaxies plays an important role in galaxy formation and evolution. Mergers could trigger key evolutionary phases such as starburst activities and active accretion periods onto supermassive black holes at the centres of galaxies. We aim to detect mergers and merger stages (pre- and post-mergers) across cosmic history. Our main goal is to test whether it is more beneficial to detect mergers and their merger stages simultaneously or hierarchically. In addition, we wis",{"id":100,"funder":7,"programme":8,"title":101,"piName":102,"institution":103,"country":12,"year":13,"amount":14,"abstract":104},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-003","Organoids in pediatric cancer research","Jarno Drost","Princess Máxima Center","Over the past decade, organoid technology has emerged as a transformative tool in biomedical research, enabling the development of physiologically relevant models of both healthy and malignant tissues. While this technology has substantially advanced our understanding of adult cancers, its application in pediatric oncology remains limited. Pediatric tumors are not only biologically distinct from adult malignancies but also present a lower incidence, posing additional challenges for model develop",{"id":106,"funder":7,"programme":8,"title":107,"piName":108,"institution":14,"country":14,"year":13,"amount":14,"abstract":109},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-149","Adding colour to the Zernike wavefront sensor: Advantages of including multi-wavelength measurements for wavefront reconstruction","Matthew A. Kenworthy","Context . To directly image Earth-like planets, contrast levels of 10 −8 −10 −10 are required. The next generation of instruments will need wavefront control below the nanometer level to achieve these goals. The Zernike wavefront sensor (ZWFS) is a promising candidate thanks to its sensitivity, which reaches the fundamental quantum information limits. However, its highly non-linear response restricts its practical use case. Aims . We aim to demonstrate the improvement in robustness of the ZWFS b",{"id":111,"funder":7,"programme":8,"title":112,"piName":113,"institution":114,"country":115,"year":13,"amount":14,"abstract":116},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-166","Reproducibility, Replicability, and Insights into Visual Document Retrieval with Late Interaction","Andrew Yates","Johns Hopkins University","US","Visual Document Retrieval (VDR) is an emerging research area that focuses on encoding and retrieving document images directly, bypassing the dependence on Optical Character Recognition (OCR) for document search. A recent advance in VDR was introduced by ColPali, which significantly improved retrieval effectiveness through a late interaction mechanism. ColPali's approach demonstrated substantial performance gains over existing baselines that do not use late interaction on an established benchmark",{"id":118,"funder":7,"programme":8,"title":119,"piName":120,"institution":121,"country":122,"year":13,"amount":14,"abstract":123},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-195-085","Taking democracy's temperature: The (in)stability and covariates of populist attitudes","Marie‐Isabel Theuwis","Université Libre de Bruxelles","BE","Abstract Populism among citizens is often perceived as a problem for democracies due to its rejection of representative practices. In response, scholars have put forward new democratic designs that enhance the democratic system's inclusiveness and popular control, thereby aiming to decrease populism among citizens, or so‐called populist attitudes. However, it is not known whether populist attitudes are even changeable, and whether they respond to such democratic improvements or merely reflect th",{"id":125,"funder":7,"programme":8,"title":126,"piName":127,"institution":128,"country":12,"year":13,"amount":14,"abstract":129},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-176","Occurrence of nucleoside-bacteriohopanepolyol in high latitude soils: evidence of environmental controls on bacterial lipid membrane distributions","Darci Rush","Royal Netherlands Institute for Sea Research","Recently, the analysis of non-derivatised bacteriohopanepolyols (BHPs) by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS 2 ) revealed a broad structural diversity in this lipid class. Multiple unique BHPs with nucleoside-type polar head groups (Nu-BHPs) were identified in soils. Nu-BHPs had previously been identified in high abundances in soil organic matter, but only by analysing acetylated BHPs, which hindered their structural elucidation. In this st",{"id":131,"funder":7,"programme":8,"title":132,"piName":133,"institution":14,"country":14,"year":13,"amount":14,"abstract":134},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-211-255","Robots en nuestra niebla: Una etnógrafa en el nuevo mundo laboral","Anastasia V. Sergeeva","¿Qué significan los robots en el futuro del trabajo? Si bien las imágenes de unos robots cada vez más capacitados nos fascinan una y otra vez, los relatos situados de robots en funcionamiento ilustran un panorama radicalmente diferente. Basándome en las teorías de la inseparabilidad entre las agencias humanas y las máquinas y en las etnografías de los robots en la cirugía, la hostelería y el cuidado de personas mayores, analizo cómo, en lugar de automatización, los robots dan como resultado reco",{"id":136,"funder":7,"programme":8,"title":137,"piName":138,"institution":20,"country":12,"year":13,"amount":14,"abstract":139},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-117","Confronting Europe’s toxics trade from below: the contested global legacy of the 1976 Seveso disaster","Koen van Zon","The 1976 Seveso disaster and its scandal-ridden aftermath had a lasting legacy that extended to the European Community (EC) and even beyond. When hazardous waste from the Seveso disaster site went missing, it generated a pan-European media scandal and a powerful symbol of the risks that modern industrialized capitalism produced. The scandal also revealed the perverse mechanisms that facilitated and even encouraged the dumping of chemical waste in and outside Europe. A variety of societal groups,",{"id":141,"funder":7,"programme":8,"title":142,"piName":143,"institution":144,"country":12,"year":13,"amount":14,"abstract":145},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-106","Refined Chabauty–Kim computations for the thrice-punctured line over $$\\mathbb {Z}[1\u002F6]$$","Martin Lüdtke","University of Groningen","Abstract The Chabauty–Kim method and its refined variant by Betts and Dogra aim to cut out the S -integral points $$X(\\mathbb {Z}_S)$$ \u003Cmml:math xmlns:mml=\"http:\u002F\u002Fwww.w3.org\u002F1998\u002FMath\u002FMathML\"> \u003Cmml:mrow> \u003Cmml:mi>X\u003C\u002Fmml:mi> \u003Cmml:mo>(\u003C\u002Fmml:mo> \u003Cmml:msub> \u003Cmml:mi>Z\u003C\u002Fmml:mi> \u003Cmml:mi>S\u003C\u002Fmml:mi> \u003C\u002Fmml:msub> \u003Cmml:mo>)\u003C\u002Fmml:mo> \u003C\u002Fmml:mrow> \u003C\u002Fmml:math> on a curve inside the p -adic points $$X(\\mathbb {Z}_p)$$ \u003Cmml:math xmlns:mml=\"http:\u002F\u002Fwww.w3.org\u002F1998\u002FMath\u002FMathML\"> \u003Cmml:mrow> \u003Cmml:mi>X\u003C\u002Fmml:mi> \u003Cmml:mo>",{"id":147,"funder":7,"programme":8,"title":148,"piName":149,"institution":150,"country":26,"year":13,"amount":14,"abstract":151},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-044","Fungal-mediated soil aggregation as a mechanism for carbon stabilization","Elly Morriën","Institute for Biodiversity","Soils can potentially be turned into net carbon sinks for atmospheric carbon to offset anthropogenic greenhouse gas emissions. Occlusion of soil organic carbon in soil aggregates is a key mechanism, which temporarily protects it from decomposition by soil organisms. Filamentous fungi are recognized for their positive role in the formation and stabilization of aggregates. In this review, we assess the current knowledge of the contribution of fungi to soil aggregation and set a new research agenda",{"id":153,"funder":7,"programme":8,"title":154,"piName":155,"institution":156,"country":157,"year":13,"amount":14,"abstract":158},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-055","Progressive oxygenation of developing leaves directs morphogenesis","Daan A. Weits","Institute of Plant Biology","HU","Abstract Oxygen availability underpins energy production in multicellular organisms, yet internal oxygen gradients arise in both plants and animals. Plants sense these variations via the PLANT CYSTEINE OXIDASE branch of the N-degron pathway, which regulates the stability of key transcription factors. Originally linked to metabolic control, this pathway recently emerged as a development regulator. While the shoot apical meristem was shown to be hypoxic, the oxygen dynamics of organs originating f",{"id":160,"funder":7,"programme":8,"title":154,"piName":155,"institution":156,"country":157,"year":13,"amount":14,"abstract":158},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-104",{"id":162,"funder":7,"programme":8,"title":163,"piName":164,"institution":165,"country":12,"year":13,"amount":14,"abstract":166},"openalex-nederlandse-organisatie-voor-wetenschapp-award-0-16-vidi-171-061","Living Together Apart: Quantitative Perspectives on the Costs and Benefits of a Multipartite Genome Organization in Viruses","Marcelle L. Johnson","Netherlands Institute of Ecology","BACKGROUND: Multipartite viruses individually package their multiple genome segments into virus particles, necessitating the transmission of multiple virus particles for effective viral spread. This dependence poses a cost in the form of reduced transmission compared to monopartite viruses, which only have a single genome segment. The notable cost of a multipartite genome organization has spurred debate on why multipartite viruses are so common among plant viruses, including a search for benefit",{"id":168,"funder":7,"programme":8,"title":46,"piName":47,"institution":48,"country":12,"year":13,"amount":14,"abstract":169},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-190","The intervention had limited benefits for cognition and psychosocial well-being, but (longer) group-based learning interventions may build up social and motivational reserves protecting against morbidity. Research with larger samples and a no-training control sample is needed to further support these findings.",{"id":171,"funder":7,"programme":8,"title":172,"piName":173,"institution":174,"country":12,"year":13,"amount":14,"abstract":175},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-133","Structure-in-Void Quasi-Bound State in the Continuum Metasurface for Deeply Subwavelength Nanostructure Metrology","A. Femius Koenderink","Institute for Atomic and Molecular Physics",", which underlies the pronounced resonant wavelength shift driven by similarly large changes in the effective index caused by extremely tiny critical dimension variations. This approach could impact critical dimension measurements in semiconductor metrology, as it works at the high throughput of optical measurements while performing at the high resolution of scanning electron microscopy.",{"id":177,"funder":7,"programme":8,"title":178,"piName":179,"institution":81,"country":12,"year":13,"amount":14,"abstract":180},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-2131313","Metamaterial that learns shape changes by using contrastive learning – METAMATERIALS 2025","Yao Du","Learning to change shape is a fundamental strategy of adaptation and evolution in crossing scales from cells to animals. Synthetic materials can also exhibit complex shape changing capabilities, but lack the ability to learn. Here, we build metamaterials that can learn complex changes by using a constrastive learning scheme. By progressively updating their local stiffnesses, our metamaterials are able to forget and learn new shape changes in sequence, learn multiple shape changes that break reci",{"id":182,"funder":7,"programme":8,"title":178,"piName":179,"institution":81,"country":12,"year":13,"amount":14,"abstract":180},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-213131",{"id":184,"funder":7,"programme":8,"title":185,"piName":186,"institution":165,"country":12,"year":13,"amount":14,"abstract":187},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-203-098","Carbon sedimentation in shallow floodplain lakes","Belén Franco‐Cisterna","Abstract Shallow lakes are increasingly recognized as important sites for organic carbon (OC) storage. However, the drivers of OC deposition in shallow floodplain lakes remain unclear due to complex terrestrial and aquatic interactions. Using 8 yr of monthly sediment trap data in a cross‐ecosystem experiment on six UK shallow lakes of varying riverine connectivity, we investigated the role of allochthonous (fluvial materials) vs. autochthonous (phytoplankton production) deposits as the OC supply",{"id":189,"funder":7,"programme":8,"title":190,"piName":191,"institution":192,"country":12,"year":13,"amount":14,"abstract":193},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-198-018","The role of temperature, deuterium pressure and residual gases in deuterium retention and outgassing of lithium deuterium co-deposits","Maria Morbey","Dutch Institute for Fundamental Energy Research","Abstract Liquid lithium (Li) divertor concepts offer a promising solution for managing the extreme heat fluxes expected in future fusion reactors. However, lithium’s strong affinity for hydrogen isotopes raises concerns regarding tritium inventory requirements and tritium breeding ratio. In particular, the lack of studies on tritium-lithium co-deposits is critical, as such co-deposits may contribute significantly to tritium retention in inaccessible areas, complicating tritium recovery. High-tem",{"id":195,"funder":7,"programme":8,"title":196,"piName":197,"institution":198,"country":122,"year":13,"amount":14,"abstract":199},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-072","Molecular Engineering of Interlayer Exciton Delocalization in 2D Perovskites","Wouter Van Gompel","Hasselt University",", the interlayer hybridization is lost, resulting in traditional quantum well properties. This study reveals new molecular engineering design principles to control excitons in 2D perovskites, emphasizing the importance of active π-core orientation and energetic band alignment─marking a critical step toward harnessing active organic cations in perovskite optoelectronics.",{"id":201,"funder":7,"programme":8,"title":202,"piName":203,"institution":204,"country":12,"year":13,"amount":14,"abstract":205},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-074","The Escherichia coli replication initiator DnaA is titrated on the chromosome","Lorenzo Olivi","Wageningen University & Research","DNA replication initiation is orchestrated in bacteria by the replication initiator DnaA. Two models for regulation of DnaA activity in Escherichia coli have been proposed: the switch between an active and inactive form, and the titration of DnaA on the chromosome. Although proposed decades ago, experimental evidence of a titration-based control mechanism is still lacking. Here, we first identified a conserved high-density region of binding motifs near the origin of replication, an advantageous ",{"id":207,"funder":7,"programme":8,"title":208,"piName":209,"institution":210,"country":55,"year":13,"amount":14,"abstract":211},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-193-037","Is there anybody out there? Ultrafast Rydberg–valence interactions in the photodissociation of trimethylamine","D. J. Hughes","University of Southampton","Trimethylamine (TMA) is a tertiary aliphatic amine that stands as a potential marker for life beyond Earth due to only being naturally produced via biotic means. However, its propensity to undergo photodissociation in the gas phase when excited by a deep ultraviolet photon means that its amine daughter product could serve as an additional biomarker and confirmational spectral signature of TMA in exoplanetary atmospheres. The photochemistry of TMA is dominated by strong Rydberg-valence state inte",{"id":213,"funder":7,"programme":8,"title":214,"piName":215,"institution":20,"country":12,"year":13,"amount":14,"abstract":216},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-128","Surfactant Assemblies Directing Chemical Transfer Cascades in Convective Marangoni Flow Pumps","Peter A. Korevaar","Abstract Convective Marangoni flow pumps can drive liquid streams in microfluidic devices and allow static channel layouts to be replaced by “virtual” boundaries that emerge in the liquid phase. However, while transfer from location A → location B can be modified easily via physicochemical control over the surface tension gradients involved, it remains a challenge to establish chemical transfer cascades A → B → C, which is prerequisite to more complex reconfigurable liquid systems. Here, a botto",{"id":218,"funder":7,"programme":8,"title":219,"piName":220,"institution":32,"country":12,"year":13,"amount":14,"abstract":221},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-211-003","The situational character of prison violence: An exploratory qualitative study","Dante Hoek","Given the detrimental effects of prison violence, understanding why and how incidents occur is necessary. This explorative qualitative research on prison violence investigates potentially violent situations between incarcerated men. Through in-depth interviews with 22 incarcerated men from 3 Dutch prisons and 2 formerly incarcerated men, we offer insight into the situational circumstances of prison violence. The findings reveal three distinct categories of situations where violence can occur: wh",{"id":223,"funder":7,"programme":8,"title":224,"piName":225,"institution":14,"country":14,"year":13,"amount":14,"abstract":226},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-191-091","How can we achieve a good measurement of attentional control?","Alodie Rey-Mermet","Attentional control refers to the basic ability necessary to maintain a goal and goal-relevant features in the face of distraction. Many researchers conceptualize attentional control as a psychometric construct that can explain individual differences across experimental tasks and situations. However, recent research has challenged this idea by observing difficulties with establishing reliable and valid measures of attentional control. The goal of the present theoretical review is threefold: (1) ",{"id":228,"funder":7,"programme":8,"title":229,"piName":230,"institution":231,"country":232,"year":13,"amount":14,"abstract":233},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-09150172110034","Association Between Parental Social Position and Childhood Overweight: Mediation by Lifestyle and \u003Cscp>BMI\u003C\u002Fscp> Patterns During Pregnancy","Camille Le Gal","Université Paris Cité","FR","In high-income countries, children born to parents with low socio-economic position (SEP) or with non-Western ethnicity are disproportionally affected by obesity as early as preschool age. We assessed how much of these associations were mediated by parental lifestyle and BMI patterns during pregnancy. We characterised 5-6 years old children with or without overweight from the French Etude Longitudinale Française depuis l'Enfance (ELFE) (n = 8584) and the Dutch Generation R birth cohorts (n = 651",{"id":235,"funder":7,"programme":8,"title":236,"piName":237,"institution":238,"country":26,"year":13,"amount":14,"abstract":239},"openalex-nederlandse-organisatie-voor-wetenschapp-award-project-number-vi-vidi-213-037","Initial shoot regeneration in the selenium hyperaccumulator Neptunia amplexicaulis and in vitro test system for selenium tolerance and accumulation","Bennet Buhmann","Leibniz University Hannover","DM. This project presents the first protocol for inducing early stages of development of indirect shoot organogenesis in N. amplexicaulis from hypocotyl and root explants as prerequisite for genetic transformation, though completing the regeneration cycle remains challenging. Neptunia amplexicaulis hyperaccumulates selenium also under in vitro conditions.",{"id":241,"funder":7,"programme":8,"title":242,"piName":243,"institution":244,"country":12,"year":13,"amount":14,"abstract":245},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-1711319","Pain Coping in Patients With Chronic Migraine and Medication Overuse Headache","Gisela M. Terwindt","Leiden University Medical Center","BACKGROUND: Chronic migraine (CM) is a leading cause of disability and often linked to medication overuse headache (MOH). Psychological factors, such as pain coping, may contribute to chronification and medication overuse. While behavioral therapy can help, identifying patients who will benefit remains challenging. This study compared pain coping in individuals with CM and MOH to those with episodic migraine (EM) and controls without headache. It also assessed whether baseline pain coping in CM ",{"id":247,"funder":7,"programme":8,"title":248,"piName":249,"institution":250,"country":12,"year":13,"amount":14,"abstract":251},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-062","Mechanical characterization of silicon for the ETpathfinder test masses","G. A. Iandolo","Maastricht University","The next generation of gravitational-wave detectors, such as the Einstein Telescope, is designed to reduce noise in a wide band of frequencies compared to the current generation, through the use of new technologies. ETpathfinder, designed as an R&D facility for these technologies, is a prototype for which the mirrors were chosen to be made of crystalline silicon, produced by the Leibniz-Institut für Kristallzüchtung. This material choice was made to pave the way for a low thermal noise level",{"id":253,"funder":7,"programme":8,"title":254,"piName":255,"institution":14,"country":14,"year":13,"amount":14,"abstract":256},"openalex-nederlandse-organisatie-voor-wetenschapp-award-680-47-535","On the asymptotic nature of cosmological effective theories","Carlos Duaso Pueyo","Acknowledgements: We would like to thank Calvin Chen, Jordan Cotler, Laura Engelbrecht, Sadra Jazayeri, Mang Hei Gordon Lee, Scott Melville, Ryo Namba, Guilherme Pimentel, Andrea Sanfilippo, and Yoav Zigdon for useful discussions. E.P. has been supported in part by the research program VIDI with Project No. 680-47-535, which is (partly) financed by the Netherlands Organisation for Scientific Research (NWO). C.M. is supported by Science and Technology Facilities Council (STFC) training grant ST\u002FW",{"id":258,"funder":7,"programme":8,"title":259,"piName":260,"institution":261,"country":12,"year":13,"amount":14,"abstract":262},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-183","MEANtools integrates multi-omics data to identify metabolites and predict biosynthetic pathways","Kumar Saurabh Singh","Utrecht University","During evolution, plants have developed the ability to produce a vast array of specialized metabolites, which play crucial roles in helping plants adapt to different environmental niches. However, their biosynthetic pathways remain largely elusive. In the past decades, increasing numbers of plant biosynthetic pathways have been elucidated based on approaches utilizing genomics, transcriptomics, and metabolomics. These efforts, however, are limited by the fact that they typically adopt a target-b",{"id":264,"funder":7,"programme":8,"title":265,"piName":266,"institution":204,"country":12,"year":13,"amount":14,"abstract":267},"openalex-nederlandse-organisatie-voor-wetenschapp-award-v1-vidi-195-026","Caring policy-relevant knowledge? The case of the Brazilian Platform for Biodiversity and Ecosystem Services","Adriana Ressiore C.","Science-policy interfaces like the Brazilian Platform for Biodiversity and Ecosystem Services (BPBES) aim to provide policy-relevant knowledge that guides decision-makers in addressing the current biodiversity crisis. At the same time, dominant approaches to policy-relevant knowledge have been widely challenged for relying on a misguided linear model that treats science and policy as separate domains, presenting the former through depoliticized ideals of neutrality and objectivity while prioriti",{"id":269,"funder":7,"programme":8,"title":270,"piName":271,"institution":204,"country":12,"year":13,"amount":14,"abstract":272},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-211-132","Navigating the politics of transformational adaptation in international climate negotiations","Robbert Biesbroek","Transformational adaptation to climate risks is an emerging topic in international climate negotiations. However, political views diverge on the desirability and feasibility of introducing transformational adaptation as a new concept. While scientific efforts to clarify its meaning are necessary, only by critically reflecting on the political nature of the concept can the negotiations move forward.",{"id":274,"funder":7,"programme":8,"title":275,"piName":276,"institution":32,"country":12,"year":13,"amount":14,"abstract":277},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-036","The role of the body in altered facial emotion perception in autism and social anxiety","Julia Folz","Alterations in the perception of facial emotional expression and their physiological resonance, as well as in accurately sensing bodily states (i.e., interoception) have been reported in both autism and social anxiety. In the current study, we aimed to examine the association between physiological responses, their sensation, and facial emotion perception in individuals on the autism spectrum (N = 40), individuals with social anxiety (N = 27) and neurotypical controls (N = 40). Participants first",{"id":279,"funder":7,"programme":8,"title":280,"piName":281,"institution":282,"country":12,"year":13,"amount":14,"abstract":283},"openalex-nederlandse-organisatie-voor-wetenschapp-award-decode-vi-vidi-223-088","The chemical interaction between plants and the rhizosphere microbiome","Harro J. Bouwmeester","Amsterdam University of Applied Sciences","Research into the interaction between plants and the soil microbiota has expanded rapidly and is unravelling a plethora of interactions between plants and their root microbiota. The rhizosphere exhibits remarkable chemical diversity, driven by an evolutionary arms race. Through these chemicals, plants shape the rhizosphere microbiome using different mechanisms: organic carbon provision, antimicrobial compound production, and exudation of microbiota recruitment signals. Modern high-input agricult",{"id":285,"funder":7,"programme":8,"title":286,"piName":287,"institution":261,"country":12,"year":13,"amount":14,"abstract":288},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-011","6 × 2 pt: Forecasting gains from joint weak lensing and galaxy clustering analyses with spectroscopic-photometric galaxy cross-correlations","Harry Johnston","Accurate knowledge of galaxy redshift distributions is crucial in the inference of cosmological parameters from large-scale structure data. We explore the potential for enhanced self-calibration of photometric galaxy redshift distributions, n ( z ), through the joint analysis of up to six two-point functions. Our 3 × 2 pt configuration comprises photometric shear, spectroscopic galaxy clustering, and spectroscopic-photometric galaxy-galaxy lensing (GGL). We expand this to include spectroscopic-p",{"id":290,"funder":7,"programme":8,"title":291,"piName":292,"institution":293,"country":294,"year":13,"amount":14,"abstract":295},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-195-135","Cognitive Load and Challenges in Self-regulation: An Introduction and Reflection on the Topical Collection","Anique B. H. de Bruin","Department of Education","ES","includes seven empirical papers, two review papers, one meta-analysis, and a discussion paper. These contributions build on the EMR model by testing its assumptions, linking it to motivation, and refining our understanding of the basis of effort ratings in learning. Among other findings, the findings in the topical collection (1) show that feedback valence can affect participants' perceived task effort and their willingness to invest effort via feelings of challenge and threat, (2) provide the f",{"id":297,"funder":7,"programme":8,"title":298,"piName":299,"institution":14,"country":14,"year":13,"amount":14,"abstract":300},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-085","Eigenvalue bounds for distance-edge colorings","Aida Abiad","For a fixed positive integer $t$, we consider the graph colouring problem in which edges at distance at most $t$ are given distinct colours. We obtain sharp lower bounds for the distance-$t$ chromatic index, the least number of colours necessary for such a colouring. Our bounds are of algebraic nature; they depend on the eigenvalues of the line graph and on a polynomial which can be found using integer linear programming methods. We show several graph classes that attain equality for our bounds,",{"id":302,"funder":7,"programme":8,"title":303,"piName":304,"institution":305,"country":294,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-041","Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence","Marta Mel&#x00E9","Barcelona Supercomputing Center",{"id":307,"funder":7,"programme":8,"title":308,"piName":309,"institution":310,"country":12,"year":13,"amount":14,"abstract":311},"openalex-nederlandse-organisatie-voor-wetenschapp-award-0-16-vidi-185-174","Race in televised football: insights from behind-the-scenes within major English football media organizations","Jacco van Sterkenburg","Erasmus University Rotterdam","\u003Cp dir=\"ltr\">This article presents findings from an ethnographic study that looked at how football media professionals working at major English football TV stations give meaning to race and ethnicity in their working practices. We got access to the main English televised football organizations to do in-depth interviews and participant observations for several months and examine the daily practices, routines and meaning-making of football media professionals in these organizations. The main resea",{"id":313,"funder":7,"programme":8,"title":314,"piName":315,"institution":282,"country":12,"year":13,"amount":14,"abstract":316},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-201-065","Daily Parental Responses To Disruptive Child Behavior: A Multilevel Latent Profile Analysis","Merlin Nieterau","= 5.88; 47% girls) collected over 14 days (2,067 assessments). Using multilevel latent profile analyses, we identified four behavioral patterns. Most families alternated between days with less and days with more disruptive behavior and harshness. Giving in to children's demands was rare in all families. Our findings indicate that in most families with elevated disruptive child behavior, behavioral patterns vary across days, with disruptive behavior and parental harshness, but not giving in to ch",{"id":318,"funder":7,"programme":8,"title":319,"piName":320,"institution":261,"country":12,"year":13,"amount":14,"abstract":321},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-108","Finding large independent sets in networks using competitive dynamics","M. N. Mooij","Abstract Many decision-making algorithms draw inspiration from the inner workings of individual biological systems. However, it remains unclear whether collective behaviour among biological species can also lead to solutions for computational tasks. By studying the coexistence of species that interact through simple rules on a network, we demonstrate that the underlying dynamical system can recover near-optimal solutions to the maximum independent set problem – a fundamental, computationally har",{"id":323,"funder":7,"programme":8,"title":324,"piName":325,"institution":14,"country":14,"year":13,"amount":14,"abstract":326},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-number-18388-","The DRAGON benchmark for clinical NLP","Joeran S. Bosma","Artificial Intelligence can mitigate the global shortage of medical diagnostic personnel but requires large-scale annotated datasets to train clinical algorithms. Natural Language Processing (NLP), including Large Language Models (LLMs), shows great potential for annotating clinical data to facilitate algorithm development but remains underexplored due to a lack of public benchmarks. This study introduces the DRAGON challenge, a benchmark for clinical NLP with 28 tasks and 28,824 annotated medic",{"id":328,"funder":7,"programme":8,"title":329,"piName":42,"institution":20,"country":12,"year":13,"amount":14,"abstract":330},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-195-085","Does it Matter if You’re Left or Right? Studying Left- and Right-Wing Populist Citizens’ Support for Deliberative Mini-Publics","Contains fulltext : 326911.pdf (Publisher’s version ) (Open Access)",{"id":332,"funder":7,"programme":8,"title":333,"piName":334,"institution":335,"country":12,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-452-16-015","Multimodal brain imaging of insomnia, depression and anxiety symptoms indicates transdiagnostic commonalities and differences","Siemon C. de Lange","Netherlands Institute for Neuroscience",{"id":337,"funder":7,"programme":8,"title":338,"piName":339,"institution":340,"country":232,"year":13,"amount":14,"abstract":341},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-070","Carbon Emissions From Fires in Eastern Siberian Larch Forests","Clement J. F. Delcourt","Centre National de la Recherche Scientifique",") stemmed from organic soil layers. These results suggest that severe fires in Cajander larch forests can result in combustion rates comparable to those observed in North American boreal forests and exceeding those previously reported for other forest types and burning conditions in Siberia. Carbon combustion was driven by both fire weather conditions and landscape variables, with pre-fire organic soil depth being the strongest predictor across our plots. Our study highlights the need to better ",{"id":343,"funder":7,"programme":8,"title":344,"piName":345,"institution":81,"country":12,"year":13,"amount":14,"abstract":346},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-211-055","Establishing the construct and predictive validity of brief measures of affective polarization","Jakob Kasper","Abstract Measuring affective polarization, defined as the liking for one's political ingroup and the dislike for political outgroups, poses methodological challenges in multiparty systems: evaluations of seven, 13 or even more parties in a survey are costly, time‐consuming and demanding. Some studies therefore use subsets of parties to create brief affective polarization measures. However, it is unclear how this affects the construct and predictive validity of these brief measures, potentially c",{"id":348,"funder":7,"programme":8,"title":349,"piName":350,"institution":14,"country":14,"year":13,"amount":14,"abstract":351},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-085","Physics-Informed Sylvester Normalizing Flows for Bayesian Inference in Magnetic Resonance Spectroscopy","Julian P. Merkofer","Magnetic resonance spectroscopy (MRS) is a non-invasive technique to measure the metabolic composition of tissues, offering valuable insights into neurological disorders, tumor detection, and other metabolic dysfunctions. However, accurate metabolite quantification is hindered by challenges such as spectral overlap, low signal-to-noise ratio, and various artifacts. Traditional methods like linear-combination modeling are susceptible to ambiguities and commonly only provide a theoretical lower bo",{"id":353,"funder":7,"programme":8,"title":354,"piName":355,"institution":356,"country":115,"year":13,"amount":14,"abstract":357},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-191-210","Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex","Ceci Verbaarschot","University of Pittsburgh","Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity can be reliably conveyed, two issues that prevent creating more complex naturalistic sensations are a lack of methods to effectively scan the large stimulus parameter space and difficulties with assessing percept quality. Here, we address both challenges with an experimental paradigm that enables three male individuals with te",{"id":359,"funder":7,"programme":8,"title":360,"piName":361,"institution":362,"country":363,"year":13,"amount":14,"abstract":364},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-188-014","MuSK is a substrate for CaMK2β but this interaction is dispensable for MuSK activation in vivo","Jakob Prömer","Medical University of Vienna","AT","The neuromuscular junction (NMJ) is the unique interface between lower motor neurons and skeletal muscle fibers and is indispensable for muscle function. Tight control of its localized formation at the center of every muscle fiber, and maintenance throughout lifetime are sustained by muscle-specific kinase (MuSK). MuSK acts as central regulator of acetylcholine receptor clustering at the postsynapse. Localized and temporally controlled signaling of MuSK is primarily achieved by tyrosine autophos",{"id":366,"funder":7,"programme":8,"title":367,"piName":368,"institution":14,"country":14,"year":13,"amount":14,"abstract":369},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-201-133","Mixture Multigroup Structural Equation Modeling for Ordinal Data","Andres Felipe Perez Alonso","Social scientists often compare groups in terms of relations between latent variables (LV) (often called structural relations) using Structural Equation Modeling (SEM). LVs are measured indirectly by questionnaires; thus, measurement invariance must be evaluated before comparisons can be made. To efficiently compare many groups, the recently proposed Mixture Multigroup SEM (MMG-SEM) clusters groups based on their structural relations while accounting for measurement (non-)invariance. However, th",{"id":371,"funder":7,"programme":8,"title":372,"piName":373,"institution":374,"country":12,"year":13,"amount":14,"abstract":375},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-087","A note on the core of 2-matching games","Lucy Verberk","Eindhoven University of Technology","Cooperative 2-matching games are a generalization of cooperative matching games, where the value function is given by maximum-weight b -matchings, for a vertex capacity vector b ≤ 2 . We show how to separate over the core of 2-matching games in polynomial time, fixing a small flaw in the literature, and prove the existence of a compact extended formulation for it.",{"id":377,"funder":7,"programme":8,"title":378,"piName":379,"institution":380,"country":294,"year":13,"amount":14,"abstract":381},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-030","Controls of focused fluid release in subduction zones: insights from experimental dehydration of brucite vein networks in serpentinite","Manuel D. Menzel","Instituto Andaluz de Ciencias de la Tierra","). Tracing the pre-existing brucite vein network, these aggregates can form a transient network of interconnected, highly permeable fluid channels that allows drainage and may enhance open-system exchange with neighboring lithologies. Infiltration of reduced external fluids can trigger redox dehydration of magnetite + antigorite to Fe-rich olivine, which renews porosity and propagates focused fluid flow. The distribution of brucite and magnetite, especially as vein networks, therefore has a firs",{"id":383,"funder":7,"programme":8,"title":384,"piName":385,"institution":282,"country":12,"year":13,"amount":14,"abstract":386},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-452-17-011","A harsher reality for adolescents with depression on social media","Loes Janssen","= 15.98; 16.9% clinically depressed), we assessed their level of depression and then monitored their social media activities and experiences daily for 100 subsequent days. Depressed adolescents did not differ from their non-depressed peers in the frequency of posting and the time spent scrolling. However, they reported feeling twice as insecure after scrolling, nearly twice as rejected during online communication with friends, and significantly more preoccupied with feedback. Our findings unders",{"id":388,"funder":7,"programme":8,"title":389,"piName":390,"institution":391,"country":115,"year":13,"amount":14,"abstract":392},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-116","Gradient matching accelerates mixed-effects inference for biochemical networks","Yulan B. van Oppen","Biotechnology Institute","MOTIVATION: Single-cell time series data often exhibit significant variability within an isogenic cell population. When modeling intracellular processes, it is therefore more appropriate to infer parameter distributions that reflect this variability, rather than fitting the population average to obtain a single point estimate. The Global Two-Stage (GTS) approach for nonlinear mixed-effects (NLME) models is a simple and modular method commonly used for this purpose. However, this method is comput",{"id":394,"funder":7,"programme":8,"title":395,"piName":396,"institution":397,"country":12,"year":13,"amount":14,"abstract":398},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-016-16-316-","Stem cell culture conditions affect in vitro differentiation potential and mouse gastruloid formation","Marloes Blotenburg","Royal Netherlands Academy of Arts and Sciences","Aggregating low numbers of mouse embryonic stem cells (mESCs) and inducing Wnt signalling generates 'gastruloids', self-organising complex structures that display an anteroposterior organisation of cell types derived from all three germ layers. Current gastruloid protocols display considerable heterogeneity between experiments in terms of morphology, elongation efficiency, and cell type composition. We therefore investigated whether altering the mESC pluripotency state would provide more consist",{"id":400,"funder":7,"programme":8,"title":401,"piName":402,"institution":403,"country":12,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-050","Biological methane removal by groundwater trickling biofiltration for emissions reduction","Michele Laureni","Delft University of Technology",{"id":405,"funder":7,"programme":8,"title":406,"piName":407,"institution":403,"country":12,"year":13,"amount":14,"abstract":408},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-018","On the best constants of Schur multipliers of second order divided difference functions","Martijn Caspers",") is optimal for",{"id":410,"funder":7,"programme":8,"title":411,"piName":412,"institution":413,"country":12,"year":13,"amount":14,"abstract":414},"openalex-nederlandse-organisatie-voor-wetenschapp-award-ttw-vi-vidi-198-016","Does the Cortical-Depth Dependence of the Hemodynamic Response Function Differ Between Age Groups?","Luisa Raimondo","Spinoza Centre for Neuroimaging","Functional magnetic resonance imaging (fMRI) is a widely used tool to investigate the functional brain responses in living humans. Valid comparisons of fMRI results depend on consistency of the blood-oxygen-level-dependent (BOLD) hemodynamic response function (HRF). Although common statistical approaches assume a single HRF across the entire brain, the HRF differs across individuals, regions of the brain, and cortical depth. Here, we measure HRF properties in primary visual cortex (V1) using 7 T",{"id":416,"funder":7,"programme":8,"title":411,"piName":412,"institution":413,"country":12,"year":13,"amount":14,"abstract":414},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-198-016",{"id":418,"funder":7,"programme":8,"title":419,"piName":420,"institution":14,"country":14,"year":13,"amount":14,"abstract":421},"openalex-nederlandse-organisatie-voor-wetenschapp-award-0-16-vidi-189-162","Exploring active galactic nuclei and little red dots with the Obelisk simulation","M. Volonteri","The James Webb Space telescope has discovered an abundant population of broad line emitters, typical signposts for Active Galactic Nuclei (AGN). Many of these sources have red colors and a compact appearance that has led to them being named “little red dots”. In this paper, we develop a detailed framework to estimate the photometry of AGNs embedded in galaxies extracted from the O\u003Cns0:sc>BELISK\u003C\u002Fns0:sc> cosmological simulation to understand the properties of color-selected little red dots (cLRDs",{"id":423,"funder":7,"programme":8,"title":424,"piName":425,"institution":426,"country":12,"year":13,"amount":14,"abstract":427},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-91718361","HCN4 in the atrioventricular node","Jaël S. Copier","Amsterdam Neuroscience","Hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) drives the funny current in cardiac pacemaker regions. Its involvement in sinoatrial node pacemaker generation is well known, but its function in the atrioventricular (AV) node (AVN) has not intensively been studied. HCN4 is expressed in the AVN, and its expression within the AVN seems similar across mammalian species with HCN4 presence in the inferior nodal extensions, compact node, and AV bundle. The main direct regulators of",{"id":429,"funder":7,"programme":8,"title":430,"piName":431,"institution":432,"country":433,"year":13,"amount":14,"abstract":434},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-grant-639-032-733","Model Reduction for Switched Differential-Algebraic Equations with Known Switching Signal","Md. Sumon Hossain","North South University","BD","Building on our recently proposed model reduction methods for switched ordinary linear systems, we propose a comprehensive model reduction method for linear switched differential-algebraic equations (DAEs). In contrast to most other available model reduction methods for switched systems, we consider the switching signal as a given time-variance of the system. This allows us to exploit certain linear subspaces in the reduction process and also provide in general significantly smaller reduced mode",{"id":436,"funder":7,"programme":8,"title":437,"piName":438,"institution":439,"country":55,"year":13,"amount":14,"abstract":440},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-192-011","Drug resistance–associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity","Cameron L. C. Smith","University of Cambridge","Deubiquitinating enzymes function to cleave ubiquitin (Ub) moieties from modified proteins, serving to maintain the pool of free Ub in the cell while simultaneously impacting the fate and function of a target protein. Like all eukaryotes, Plasmodium parasites rely on the dynamic addition and removal of Ub for their own growth and survival. While humans possess around 100 deubiquitinases, Plasmodium contains ∼20 putative Ub hydrolases, many of which bear little to no resemblance to those of other",{"id":442,"funder":7,"programme":8,"title":443,"piName":444,"institution":445,"country":115,"year":13,"amount":14,"abstract":446},"openalex-nederlandse-organisatie-voor-wetenschapp-award--vi-vidi-191-091","The misalignment of incentives in academic publishing and implications for journal reform","Jennifer S. Trueblood","Indiana University Bloomington","For most researchers, academic publishing serves two goals that are often misaligned-knowledge dissemination and establishing scientific credentials. While both goals can encourage research with significant depth and scope, the latter can also pressure scholars to maximize publication metrics. Commercial publishing companies have capitalized on the centrality of publishing to the scientific enterprises of knowledge dissemination and academic recognition to extract large profits from academia by ",{"id":448,"funder":7,"programme":8,"title":449,"piName":450,"institution":451,"country":12,"year":13,"amount":14,"abstract":452},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-09150172010043","Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality","Marleen Kok","The Netherlands Cancer Institute","Cancer disrupts intratumoral innate-adaptive immune crosstalk, but how the systemic immune landscape evolves during breast cancer progression remains unclear. We profiled circulating immune cells in stage I-III and stage IV triple-negative breast cancer (TNBC) patients and healthy donors (HDs). Metastatic TNBC (mTNBC) patients had reduced T cells, dendritic cells, and differentiated B cells compared to non-metastatic TNBC patients and HDs, partly linked to prior chemotherapy. Vδ1 γδ T cells from",{"id":454,"funder":7,"programme":8,"title":455,"piName":456,"institution":81,"country":12,"year":13,"amount":14,"abstract":457},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-195-041","Supporting parents to reduce children's anxiety: A meta-analysis of interventions and their theoretical components","Karen Rienks","Parent-focused interventions hold promise for reducing child anxiety, but their content varies greatly, and little is known on the intervention content. We estimated the effects of parent-focused interventions on child anxiety and the most effective combinations of theoretical components. We searched PsycINFO, Medline, and Web of Science in October 2022 for randomized trials on parent-focused interventions to reduce children's anxiety. We used robust variance estimation to estimate main effects ",{"id":459,"funder":7,"programme":8,"title":460,"piName":461,"institution":261,"country":12,"year":13,"amount":14,"abstract":462},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-031","Multiscale X-ray scattering elucidates activation and deactivation of oxide-derived copper electrocatalysts for CO2 reduction","Jim de Ruiter","O to Cu activation, whereas less active planar surface sites evolve over time. These multiscale insights highlight the dynamic and intimate relationship between electrocatalyst structure, surface-adsorbed molecules, and catalytic performance, and our in situ X-ray scattering methodology serves as an additional tool to elucidate the factors that govern electrocatalyst (de)stabilization.",{"id":464,"funder":7,"programme":8,"title":465,"piName":466,"institution":20,"country":12,"year":13,"amount":14,"abstract":467},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-037","Gas-phase, conformer-specific infrared spectra of 3-chlorophenol and 3-fluorophenol","Joost M. Bakker","bands for 3-fluorophenol. 1D torsional mode calculations were performed for 3CP to help assign possible OH torsion overtones.",{"id":469,"funder":7,"programme":8,"title":470,"piName":471,"institution":14,"country":14,"year":13,"amount":14,"abstract":472},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-049","Light and protonation-controlled complex formation between sulfate ions and a stiff-stilbene based bis(cyclopeptide)","Stefan Kubik","), give rise to different assembly states. The accessible products have 1 : 1, 1 : 2 and 2 : 2 host-guest stoichiometries and can be interconverted by light irradiation and acid\u002Fbase addition, resulting in a highly controllable responsive system that demonstrates the potential of sulfate coordination-driven supramolecular assembly.",{"id":474,"funder":7,"programme":8,"title":475,"piName":476,"institution":477,"country":26,"year":13,"amount":14,"abstract":478},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-189-044","Computational design of an improved photoswitchable psychedelic based on light absorption, membrane permeation and protein binding","Shirin Faraji","Heinrich Heine University Düsseldorf","R, retaining all important interactions of lysergic acid diethylamide (LSD), exhibits positive membrane permeability, and has a strong red-shifted absorption that would allow photocontrol in the visible spectrum.",{"id":480,"funder":7,"programme":8,"title":481,"piName":482,"institution":14,"country":14,"year":13,"amount":14,"abstract":483},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-131","Animating metamaterials with non-reciprocity","J.C. Veenstra","Complex material responses can be achieved by engineering the interactions between a material’s internal components and the geometry that organizes them. Yet even the most sophisticated designed materials remain limited compared to the adaptive, far-from-equilibrium behavior observed in living systems. This thesis explores how materials can be endowed with dynamical and autonomous behavior by embedding non-reciprocal interactions—forces that violate action-reaction symmetry—directly into their s",{"id":485,"funder":7,"programme":8,"title":486,"piName":487,"institution":488,"country":489,"year":13,"amount":14,"abstract":490},"openalex-nederlandse-organisatie-voor-wetenschapp-award-ttw-016-vidi-178-052","Assessing a Stimulator Modification for Simultaneous Noninvasive Auricular Vagus Nerve Stimulation and MRI","Vanessa Teckentrup","Trinity College Dublin","IE","BACKGROUND AND PURPOSE: The vagus nerve can be stimulated noninvasively at the ear using transcutaneous auricular vagus nerve stimulation (taVNS). Concurrent functional MRI (fMRI) permits study of taVNS-induced changes in brain dynamics, a key requisite for precision neurostimulation. However, there is no standardized protocol for how to safely apply taVNS during MRI. One major risk is temperature increase exceeding innocuous thresholds due to coupling of the emitted radio frequency (RF) pulse d",{"id":492,"funder":7,"programme":8,"title":493,"piName":494,"institution":25,"country":26,"year":13,"amount":14,"abstract":495},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-172","Structural polymorphism of α-synuclein fibrils alters the pathway of Hsc70-mediated disaggregation","Saskia C.A. de Jager","Pathological aggregation of α-synuclein into amyloid fibrils is a hallmark of synucleinopathies, including Parkinson's disease. Despite this commonality, synucleinopathies display divergent disease phenotypes that have been attributed to disease-specific three-dimensional structures of α-synuclein fibrils, each with unique toxic gain-of-function profiles. The Hsc70 chaperone is remarkable in its ability to disassemble pre-existing amyloid fibrils of different proteins in an ATP and co-chaperone-",{"id":497,"funder":7,"programme":8,"title":498,"piName":499,"institution":14,"country":14,"year":13,"amount":14,"abstract":500},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-221g-014","Social and Neurobiological Mechanisms of Risk and Resilience in Young People: The Longitudinal THRIVE-study","Elizabeth E.L. Buimer","More than half of the children and adolescents worldwide experience at least one form of childhood adversity (e.g., abuse, neglect or bullying) whilst growing up. Childhood adversity is among the strongest predictors of mental health problems in adolescence and adulthood. Yet, some individuals show resilient functioning, meaning they have good mental health and well-being despite their exposure to childhood adversity. Childhood adversity is thought to affect mental health through its impact on n",{"id":502,"funder":7,"programme":8,"title":503,"piName":504,"institution":11,"country":12,"year":13,"amount":14,"abstract":505},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-231r-031","Emotions and Reputation Learning by Audience Networks: A Research Agenda in Bureaucratic Politics","Dovilė Rimkutė","ABSTRACT Audiences that observe and interact with government agencies play a crucial role in shaping these agencies' reputations. However, existing research often treats these audience networks as monolithic, overlooking the inherent diversity in their cognitive and emotional processing of reputational information. This approach fails to account for the variations in how audiences experience and evaluate agencies. To address this gap, we propose a new research agenda focused on the role of emoti",{"id":507,"funder":7,"programme":8,"title":508,"piName":509,"institution":32,"country":12,"year":13,"amount":14,"abstract":510},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-201-084","The Democratic Justification of Academic Freedom in EU Law: Article 13 of the EU Charter, the Rule of Law Toolbox, and the Scope for EU Action","Olga Ceran","The democratic justification of academic freedom – Academic freedom and Article 2 TEU values (democracy, the rule of law) – Potential implications for the application of the EU rule of law toolbox – Complementary protection of academic freedom – Preliminary remarks on future proposals",{"id":512,"funder":7,"programme":8,"title":513,"piName":514,"institution":32,"country":12,"year":13,"amount":14,"abstract":515},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-171-049","The late Middle Pleistocene Homo erectus of the Madura Strait, first hominin fossils from submerged Sundaland","H.W.K. Berghuis","Eastern Asia yielded a rich fossil record of Pleistocene hominins, ranging from Homo erectus and the diminutive island species Homo floresiensis and Homo luzonensis , to post- erectus grade late archaic Homo (including Denisovans), and finally to anatomically modern humans. The Sunda Shelf played an important role in the dispersal and evolution of hominin populations. The shelf has been widely exposed during most of the Pleistocene, forming a landmass known as Sundaland. Today, the area holds th",{"id":517,"funder":7,"programme":8,"title":518,"piName":519,"institution":520,"country":26,"year":13,"amount":14,"abstract":521},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-041","Diverging Ethnic Hierarchies? Cultural Distance, Right-Wing Authoritarianism, and Social Distance Perceptions in the Netherlands","Hannah Soiné","University of Mannheim","Abstract The existence of hierarchies of ethnic preferences in society is well-documented. However, there is little research about how such ethnic hierarchies can be explained. Improving upon previous studies, we investigated whether individuals’ cultural distance toward ethnic outgroups and their level of right-wing authoritarianism (RWA) contribute to differences in their perception of social distance toward these groups. Our study is based on a survey in the Netherlands ( N = 1249) and provid",{"id":523,"funder":7,"programme":8,"title":524,"piName":525,"institution":150,"country":26,"year":13,"amount":14,"abstract":526},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-101","Variable responses to ocean acidification among mixotrophic protists with different lifestyles","Shai Slomka","strains responded to ocean acidification, but in different ways. The variability in their responses highlights the need for better understanding of the functional diversity among mixotrophs in order to enhance predictive understanding of their contributions to global carbon cycling in the future.",{"id":528,"funder":7,"programme":8,"title":529,"piName":530,"institution":144,"country":12,"year":13,"amount":14,"abstract":531},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-191-178","Understanding types of transitions in clinical change: An introduction from the complex dynamic systems perspective.","Jingmeng Cui","Sudden changes are common in clinical trajectories. While theoretical work in complex dynamic systems has provided mathematical theories for various types and mechanisms of change, a concrete application for the field of psychopathology is still lacking. We aim to bridge this gap by outlining an applied theoretical framework using theoretical concepts of the natural sciences for the field of clinical psychopathology, also devoting attention to issues and providing recommendations that are specif",{"id":533,"funder":7,"programme":8,"title":534,"piName":535,"institution":261,"country":12,"year":13,"amount":14,"abstract":536},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-vi-vidi-233-019","Electric-Field Control of Zero-Dimensional Topological States in Ultranarrow Germanene Nanoribbons","Lumen Eek","Reversible, all-electric control of symmetry-protected zero-dimensional modes has been a long-standing goal. In buckled honeycomb lattices, a perpendicular field couples to the staggered sublattice potential providing the required handle. We combine scanning tunneling microscopy and tight-binding theory to switch zero-dimensional topological end states reversibly on and off in ultranarrow germanene nanoribbons by tuning the electric field in the tunnel junction. Increasing the field switches off",{"id":538,"funder":7,"programme":8,"title":539,"piName":540,"institution":541,"country":26,"year":13,"amount":14,"abstract":542},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-91718364","\u003Ci>MicroRNA-26b−\u002F−\u003C\u002Fi> augments atherosclerosis, while mimic-loaded nanoparticles reduce atherogenesis","Linsey J. F. Peters","Institute for Sports Medicine","AIMS: Increasing evidence has shown that microRNAs (miRs) play a fundamental role in atherosclerosis, but the exact role of various miRs remains elusive. Preliminary data showed that, with a five-fold increase, miR-26b was highly expressed in human atherosclerotic plaques compared to healthy vessels. Therefore, we aimed to determine its cell-specific effects on atherosclerosis development and its therapeutic potential. METHODS AND RESULTS: We examined the role of miR-26b in atherosclerosis by us",{"id":544,"funder":7,"programme":8,"title":545,"piName":546,"institution":14,"country":14,"year":13,"amount":14,"abstract":547},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-917-18-338","Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes.","De Bie, Eckart","RATIONALE & OBJECTIVES: Inflammation is associated with all types of Pulmonary Hypertension (PH) both as a known cause and\u002For a putative confounder. The most common marker of inflammation, C-reactive protein (CRP), has not been widely studied in PH. This study set out to clarify if CRP informed clinical endotyping and outcomes. Methods & Measurements: Time-series clustering of longitudinal CRP levels was employed. Clinical differences between clusters were validated in three independent ",{"id":549,"funder":7,"programme":8,"title":550,"piName":551,"institution":20,"country":12,"year":13,"amount":14,"abstract":552},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-001","Ruthenium Bis-Sulfonate Complexes: Synthesis and Application in Asymmetric Hydrogenation","Olga O. Sokolova","catalyst, highlighting the impact of anion variation on catalytic asymmetric hydrogenations.",{"id":554,"funder":7,"programme":8,"title":555,"piName":556,"institution":557,"country":232,"year":13,"amount":14,"abstract":558},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-124","Representational drift shows same-class acceleration in visual cortex and artificial neural networks","Martin Vinck","Institut des Sciences Cognitives Marc Jeannerod","ABSTRACT The neural code is not fixed but shows substantial representational drift over time. It has been proposed that representational drift reflects continuous learning resulting from input-dependent plasticity. Using theoretical analysis and simulations in artificial neural networks, we show that input-dependent plasticity entails a same-class-acceleration principle: Representational drift for a given class of stimuli is predominantly caused by presenting that class of stimuli, rather than p",{"id":560,"funder":7,"programme":8,"title":561,"piName":562,"institution":144,"country":12,"year":13,"amount":14,"abstract":563},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-grant-864-11-012","Migration load, competition, and metabolic trade-offs shape spatial divergence through eco-evolutionary dynamics","David Matthias Ekkers","Abstract Evolutionary models predict that trade-offs related to resource utilization promote local specialization and diversification in spatially heterogeneous environments. However, diversification is also influenced by ecological feedback mechanisms - such as frequency-dependent resource use - and their interaction with migration. To investigate how spatial variation affects diversification, we conducted an evolution experiment exposing populations of Lactococcus cremoris to divergent selecti",{"id":565,"funder":7,"programme":8,"title":566,"piName":567,"institution":144,"country":12,"year":13,"amount":14,"abstract":568},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-093","Occurrence rate of stellar Type II radio bursts from a 100 star-year search for coronal mass ejections","David C. Konijn","Coronal mass ejections (CMEs) are major drivers of space weather in the Solar System, but their occurrence rate on other stars is unknown. A characteristic (deca-)metric radio burst with a time-frequency drift, known as a Type II radio burst, is a key observational signature of CMEs. We searched a total of 107 years of stellar data using time-frequency spectra that targeted all known stars within 100 parsecs in the LOFAR Two Metre Sky Survey (LoTSS) up to May 2023. This resulted in the largest u",{"id":570,"funder":7,"programme":8,"title":486,"piName":487,"institution":488,"country":489,"year":13,"amount":14,"abstract":490},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-178-052",{"id":572,"funder":7,"programme":8,"title":573,"piName":574,"institution":261,"country":12,"year":13,"amount":14,"abstract":575},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-106","Soil and Plant Nutrients Are Maintained—and Can Be Enhanced—by Long‐Term Frequent Fire in an Afromontane Grassland","Nicola Findlay","ABSTRACT Questions Fire is a key ecological and evolutionary force in many grassy biomes, including the Afromontane region of South Africa, where it supports critical ecosystem processes such as nutrient cycling. Anthropogenic activities are expected to alter fire regimes, with consequences for grassland nutrient dynamics and, by extension, species composition and productivity. We asked how long‐term variation in fire frequency and season of burn influences nutrient concentrations in soils and p",{"id":577,"funder":7,"programme":8,"title":578,"piName":579,"institution":403,"country":12,"year":13,"amount":14,"abstract":580},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-019","Gravity Water Waves over Constant Vorticity Flows: From Laminar Flows to Touching Waves","Francisco Gonçalves","In a recent paper, Hur and Wheeler (J Fluid Mech 896:1, 2020) proved the existence of periodic steady water waves over an infinitely deep, two-dimensional and constant vorticity flow under the influence of gravity. These solutions include overhanging wave profiles, some of which exhibit surfaces that touch at a point and thereby enclose a bubble of air. We extend these results by formulating a problem that encompasses both infinitely deep and finitely deep flows, and by proving the existence of ",{"id":582,"funder":7,"programme":8,"title":583,"piName":584,"institution":585,"country":55,"year":13,"amount":14,"abstract":586},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-016186364","Endothelial to mesenchymal transition in cardiovascular diseases: molecular insights and clinical perspectives","Ignacio Fernando Hall","The Queen's Medical Research Institute","Endothelial to mesenchymal transition (EndMT) is a process whereby endothelial cells transition to adopt a mesenchymal-like fate, e.g. to become smooth muscle cells, osteoblasts, fibroblasts, or chondrocytes. In embryonic heart development, the importance of EndMT was established several decades ago, with ECs undergoing EndMT to give rise to the endocardial cushions that ultimately develop into the cardiac valves. More recently, EndMT has been observed in various adult cardiovascular diseases. T",{"id":588,"funder":7,"programme":8,"title":589,"piName":590,"institution":426,"country":12,"year":13,"amount":14,"abstract":591},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-188-022","Dual Role of LH-GABA Neurons in Encoding Alcohol Reward and Aversive Memories","Nathan J. Marchant","Abstract One of the core aspects of alcohol use disorder is continued use despite negative consequences. Individuals with an alcohol use disorder typically engage in behaviors which represent a failure to integrate the aversive consequences of their actions. The neural mechanisms of learning about conflicting experiences remain poorly understood. Previous research has highlighted the critical role of GABAergic neurons in the Lateral Hypothalamus (LH-GABA) in rewarding memories. However, whether ",{"id":593,"funder":7,"programme":8,"title":594,"piName":595,"institution":204,"country":12,"year":13,"amount":14,"abstract":596},"openalex-nederlandse-organisatie-voor-wetenschapp-award-i-vi-vidi-193-054","Diptera flight diversity is shaped by aerodynamic constraints, scaling, and evolutionary trade-offs","Florian T. Muijres","Abstract Flight has been a key innovation in insect evolution, yet the selective and mechanistic pressures shaping their flight motor systems remain poorly understood. Here, we present a comprehensive comparative analysis of flight in Diptera (true flies), integrating morphology, wingbeat kinematics, and aerodynamics within a phylogenetic framework. We quantified morphology in 133 species spanning the Dipteran phylogenetic and size range, and for a subset of 46 species we combined high-speed ste",{"id":598,"funder":7,"programme":8,"title":599,"piName":600,"institution":204,"country":12,"year":13,"amount":14,"abstract":601},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-041","Iflaviruses in arthropods: when small is mighty","Vera I. D. Ros","Iflaviruses are arthropod-infecting viruses classified in the family Iflaviridae. The most well-studied iflaviruses are responsible for deleterious overt (symptomatic) infections in economically important insect species like honeybees and silkworms. The fact that iflaviruses are also found in mass reared insects such as crickets and flies, makes their study relevant for the food and feed industries and for biological control applications (e.g., mass reared insects for sterile insect techniques).",{"id":603,"funder":7,"programme":8,"title":604,"piName":605,"institution":20,"country":12,"year":13,"amount":14,"abstract":606},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-193-093","A test of Ca II H & K photometry for isolating massive globular clusters below the metallicity floor","Bas van Heumen","Context. The serendipitous discovery of the M31 globular cluster (GC) EXT8 has presented a significant challenge to current theories of GC formation. By finding other GCs similar to EXT8, it should become clear if and\u002For how EXT8 can fit into our current understanding of GC formation. Aims. We aim to test the potential of integrated-light narrowband Ca II H & K photometry as a proxy for the metallicity of GCs to be able to provide effective candidate selection for massive GCs below the GC me",{"id":608,"funder":7,"programme":8,"title":609,"piName":610,"institution":81,"country":12,"year":13,"amount":14,"abstract":611},"openalex-nederlandse-organisatie-voor-wetenschapp-award-016-vidi-185-068","The Social Sources Adolescents Consult for Daily Life Choices: Variations in Age and Decision Domains","Scarlett K. Slagter","INTRODUCTION: Previous research has investigated the impact of peers on adolescents' decision-making across various domains. However, adolescents are not just passive receivers of information; they actively seek advice from peers. Yet, there is limited understanding of whom adolescents turn to within their peer networks to guide their decisions. METHODS: This study explored adolescents' preferences for seeking advice within their peer network when making decisions across different decision domai",{"id":613,"funder":7,"programme":8,"title":614,"piName":615,"institution":340,"country":232,"year":13,"amount":14,"abstract":616},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-102","Freezing line of polydisperse hard spheres via direct-coexistence simulations","Antoine Castagnède","In experimental systems, colloidal particles are virtually always at least somewhat polydisperse, which can have profound effects on their ability to crystallize. Unfortunately, accurately predicting the effects of polydispersity on phase behavior using computer simulations remains a challenging task. As a result, our understanding of the equilibrium phase behavior of even the simplest colloidal model system, hard spheres, remains limited. Here, we present a new approach to map out the freezing ",{"id":618,"funder":7,"programme":8,"title":619,"piName":620,"institution":20,"country":12,"year":13,"amount":14,"abstract":621},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-203-039","Emissions Footprints of Agriculture Around the World 1970–2020: Decreasing Land Conversion, Regional Exceptions and Increasing Management Intensity","Chaidir Arsyan Adlan","-eq\u002Fton) per crop. Here, we define three clusters of crop-region pairings that help prioritize measures for future reduction in land use emissions from agricultural crops: (i) high-footprint, efficient land use (e.g., palm oil in Indonesia) where limiting conversion of high-carbon stock area has first priority, (ii) low-emission, inefficient land use (e.g., tropical cereals in Western Africa) where the focus should be on improved agricultural management to increase yields and thereby also minimi",{"id":623,"funder":7,"programme":8,"title":624,"piName":625,"institution":20,"country":12,"year":13,"amount":14,"abstract":626},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-089","Amino acids bind to phase-separating proteins and modulate biomolecular condensate stability and dynamics","Xufeng Xu","Biomolecular condensates (BCs) are ubiquitous compartments that regulate key functions in cells. BCs are surrounded by a complex intracellular environment, of which amino acids (AAs) are prominent components. However, it is unclear how AAs interact with condensate components and influence the material properties of condensates. Here, we demonstrate that phase separation is suppressed with glycine by using model heterotypic condensates composed of nucleophosmin 1 and ribosomal ribonucleic acid. T",{"id":628,"funder":7,"programme":8,"title":629,"piName":630,"institution":631,"country":12,"year":13,"amount":14,"abstract":632},"openalex-nederlandse-organisatie-voor-wetenschapp-award-nwo-vidi-18361-jw","Evaluation of tractography parameters for dentato-rubro-thalamic tract reconstruction during pediatric posterior fossa tumor surgery","Pien E. J. Jellema","University Medical Center Utrecht","OBJECTIVE: Intraoperative fiber tractography can help neurosurgeons in localizing eloquent tracts potentially displaced by tumors. In pediatric posterior fossa tumor (pPFT) patients, disturbances to the eloquent dentato-rubro-thalamic tract (DRTT) might contribute to cerebellar mutism syndrome. This study investigates the effect of fiber tractography parameters on DRTT reconstruction in pre- and intraoperative settings. METHODS: T1-weighted and diffusion MRI data were acquired from ten pPFT pati",{"id":634,"funder":7,"programme":8,"title":635,"piName":636,"institution":204,"country":12,"year":13,"amount":14,"abstract":637},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-054","Adaptations in wing morphology rather than wingbeat kinematics enable flight in small hoverfly species","Camille Le Roy","Due to physical scaling laws, size greatly affects animal locomotor ability and performance. Whether morphological and kinematic traits always jointly respond to size variation remains poorly known. Here, we examine the relative importance of morphological and kinematic changes in mitigating the consequence of size reduction on aerodynamic force production for weight support, focusing on the flight of hoverflies (Syrphidae). We compared the morphology of 28 hoverfly species, and the flight biome",{"id":639,"funder":7,"programme":8,"title":640,"piName":641,"institution":81,"country":12,"year":13,"amount":14,"abstract":642},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-201-009","How to synthesize randomized controlled trial data with meta-analytic structural equation modeling: A comparison of various d-to-rpb conversions.","Hannelies de Jonge","conversion generally performs best. However, this conversion formula is not implemented in the mainstream conversion tools. We developed a user-friendly web application entitled Effect Size Calculator and Converter (https:\u002F\u002Fhdejonge.shinyapps.io\u002FESCACO) that converts the user's primary study statistics into an effect size suitable for use in MASEM. (PsycInfo Database Record (c) 2026 APA, all rights reserved).",{"id":644,"funder":7,"programme":8,"title":645,"piName":646,"institution":647,"country":55,"year":13,"amount":14,"abstract":648},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-193-131","EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers","Manda Magdalena Marić","The Francis Crick Institute","Exonuclease EXO1 performs multiple roles in DNA replication and DNA damage repair (DDR). However, EXO1 loss is well-tolerated, suggesting the existence of compensatory mechanisms that could be exploited in DDR-deficient cancers. Using CRISPR screening, we find EXO1 loss as synthetic lethal with many DDR genes somatically inactivated in cancers, including Fanconi Anaemia (FA) pathway and BRCA1-A complex genes. We also identify the spliceosome factor and tumour suppressor ZRSR2 as synthetic lethal",{"id":650,"funder":7,"programme":8,"title":651,"piName":652,"institution":653,"country":122,"year":13,"amount":14,"abstract":654},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-159","Photonics in Flatland: challenges and opportunities for nanophotonics with 2D semiconductors","Alberto G. Curto","Ghent University","Abstract Two-dimensional (2D) semiconductors are emerging as a versatile platform for nanophotonics, offering unprecedented tunability in optical properties through exciton resonance engineering, van der Waals heterostructuring, and external field control. These materials enable active optical modulation, single-photon emission, quantum photonics, and valleytronic functionalities, paving the way for next-generation optoelectronic and quantum photonic devices. However, key challenges remain in ac",{"id":656,"funder":7,"programme":8,"title":657,"piName":658,"institution":14,"country":14,"year":13,"amount":14,"abstract":659},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-169","Ambiguous signals and efficient codes","Marianne Bauer","In many biological networks the responses of individual elements are ambiguous. We consider a scenario in which many sensors respond to a shared signal, each with limited information capacity, and ask that the outputs together convey as much information as possible about an underlying relevant variable. In a low noise limit where we can make analytic progress, we show that individually ambiguous responses optimize overall information transmission.",{"id":661,"funder":7,"programme":8,"title":662,"piName":663,"institution":335,"country":12,"year":13,"amount":14,"abstract":664},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-088","A Solanoeclepin A precursor functions as a new rhizosphere signaling molecule recruiting growth-promoting microbes under nitrogen deficiency","Lemeng Dong","Abstract Solanoeclepin A (SolA) is a triterpenoid exuded from the roots of Solanaceae plants, originally identified as hatching stimulant for plant parasitic cyst nematodes. Assuming that evolution would have selected against the production of such a fitness lowering molecule, we postulated that SolA must serve another, beneficial, role for the plant. In this study, we demonstrate that nitrogen (N) deficiency strongly increases the SolA concentration in tomato root exudate. Moreover, SolA is pro",{"id":666,"funder":7,"programme":8,"title":667,"piName":668,"institution":669,"country":363,"year":13,"amount":14,"abstract":670},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-057","A Highly Reactive Cysteine-Targeted Acrylophenone Chemical Probe That Enables Peptide\u002FProtein Bioconjugation and Chemoproteomics Analysis","David B. Konrad","University of Vienna","-dichloroacrylophenone-alkyne (CAPA), which increased the stability of the probe and the yield of its cysteine adducts. To showcase the reactivity, we performed reaction rate analyses with model reagents. The selectivity was demonstrated by specifically labeling cysteine residues within two peptides under physiological conditions. To investigate its utility toward bioconjugation reactions, we performed the stoichiometric labeling of two proteins. Remarkably, CAPA was successfully implemented as ",{"id":672,"funder":7,"programme":8,"title":673,"piName":674,"institution":61,"country":12,"year":13,"amount":14,"abstract":675},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-008","Aberrant neural activity in the peritumoral cortex underlies the progression of tumor-associated seizures","Bibi L. J. Bouwen","Seizures are frequent complications in brain tumor patients, yet the underlying neuronal mechanisms remain poorly defined. Here, we examined pathophysiological alterations in the peritumoral cortex of patients undergoing tumor resection. The synaptic activity, dendritic spine density, and gene expression of peritumoral pyramidal neurons differed significantly between patients with and without seizures. Using an inducible glioma rodent model, we characterized the progression of these alterations ",{"id":677,"funder":7,"programme":8,"title":678,"piName":679,"institution":403,"country":12,"year":13,"amount":14,"abstract":680},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-223-089","Anomalous Refractive Index Modulation and Giant Birefringence in 2D Ferrielectric CuInP \u003Csub>2\u003C\u002Fsub> S \u003Csub>6\u003C\u002Fsub>","Houssam El Mrabet Haje","Abstract 2D ferroelectric (FE) materials have opened new opportunities in non‐volatile memories, computation and non‐linear optics due to their robust polarization in the ultra‐thin limit and inherent flexibility in device integration. Recently, interest has grown in the use of 2D FEs in electro‐optics, demanding the exploration of their electronic and optical properties. In this work, the discovery of an unprecedented anomalous thickness‐dependent change in refractive index, as large as δ n ∼ 2",{"id":682,"funder":7,"programme":8,"title":683,"piName":684,"institution":81,"country":12,"year":13,"amount":14,"abstract":685},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-231s-089","Validation is the central challenge for generative social simulation: a critical review of LLMs in agent-based modeling","Maik Larooij","Recent advances in Large Language Models (LLMs) have revitalized interest in Agent-Based Models (ABMs) by enabling \"generative\" simulations, with agents that can plan, reason, and interact through natural language. These developments promise greater realism and expressive power, but also revive long-standing concerns over empirical grounding, calibration, and validation-issues that have historically limited the uptake of ABMs in the social sciences. This paper systematically reviews the emerging",{"id":687,"funder":7,"programme":8,"title":688,"piName":689,"institution":32,"country":12,"year":13,"amount":14,"abstract":690},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-723-013-007","Sulfophenylated centimeter-sized graphene membrane in a direct methanol fuel cell","Weizhe Zhang",". These findings propose functionalized graphene as an alternative to polymer membranes for electrochemical energy devices.",{"id":692,"funder":7,"programme":8,"title":693,"piName":694,"institution":204,"country":12,"year":13,"amount":14,"abstract":695},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-074","Genetic diversity, predictive protein structures, and interaction networks of Cysteine-Rich Receptor-Like Kinases in \u003Ci>Arabidopsis thaliana\u003C\u002Fi>","Elwira Smakowska‐Luzan","Abstract Cysteine-rich receptor-like kinases (CRKs) are a large subfamily of plant receptor-like kinases (RLKs) implicated in immunity and development, yet their ligands, interaction partners, and mechanistic roles remain poorly defined. We combined population-genetic analyses and AlphaFold-based structural prediction to characterise the Arabidopsis thaliana CRK family. Phylogenetic reconstruction from 69 natural accessions resolved five well-supported CRK clades. Nucleotide diversity (π) and ne",{"id":697,"funder":7,"programme":8,"title":698,"piName":699,"institution":700,"country":55,"year":13,"amount":14,"abstract":14},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-193-066","How Hard can it be to Formalize a Proof?","François Dupressoir","University of Bristol",{"id":702,"funder":7,"programme":8,"title":703,"piName":704,"institution":14,"country":14,"year":13,"amount":14,"abstract":705},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-223-075","Multiphoton interference outperforms pairwise overlaps for distinguishability characterization","S. N. van den Hoven","We propose a protocol that characterizes the pairwise overlaps of the internal modes of single photons more efficiently than pairwise Hong-Ou-Mandel characterization experiments. This protocol exploits multiphoton interference. We experimentally implement this protocol to characterize three photons. We show that our implementation of the characterization protocol outperforms the pairwise Hong-Ou-Mandel characterization, even if the Hong-Ou-Mandel characterization would have been performed in a n",{"id":707,"funder":7,"programme":8,"title":708,"piName":709,"institution":20,"country":12,"year":13,"amount":14,"abstract":710},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-201-150","Multiple brain activation patterns underlying successful visual short-term memory across the adult lifespan","Michelle G. Jansen","Cognitive task performance can be supported through multiple brain activation patterns, a concept referred to as brain degeneracy. We used a novel approach to consider brain degeneracy during a visual short-term memory task (VSTM) across the adult lifespan in the cross-sectional Cam-CAN study (n = 113, 23-87 years old). Our main goal was to identify subgroups of participants whose VSTM performance was characterized by distinct brain activation patterns. First, we identified seven brain modules t",{"id":712,"funder":7,"programme":8,"title":713,"piName":714,"institution":715,"country":716,"year":13,"amount":14,"abstract":717},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-192-045","Carbonate electrolytes manipulate lattice oxygen dynamics of oxyhydroxides toward efficient and durable water oxidation","Le Ke","Wuhan University","CN",". This work reveals the intricacy of lattice oxygen dynamics, offering opportunities for designing high-performance electrocatalysts for real-life applications.",{"id":719,"funder":7,"programme":8,"title":720,"piName":721,"institution":722,"country":723,"year":13,"amount":14,"abstract":724},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vidi-203-061","Rethinking mass transfer: A unified semianalytical framework for circular and eccentric binaries","A. Parkosidis","Astronomical Institute of the Slovak Academy of Sciences","SK","Mass transfer (MT) is a fundamental process in stellar evolution. While MT in circular orbits is well studied, observations indicate that it also occurs in eccentric ones, where theoretical models are limited. We present a new semianalytic framework for the secular orbital evolution of mass-transferring binaries that treats stars as either point masses or extended bodies. For the first time, a MT model is applicable to both circular and eccentric orbits and accommodates conservative and nonconse",{"id":726,"funder":7,"programme":8,"title":727,"piName":728,"institution":32,"country":12,"year":13,"amount":14,"abstract":729},"openalex-nederlandse-organisatie-voor-wetenschapp-award-vi-vidi-213-088","Unlocking Demography: Developing an e \u003Cscp>DNA\u003C\u002Fscp> ‐Based Toolkit to Measure Sex Ratios From Populations","Emilie A. Didaskalou","Demographic information, such as sex ratios, is essential for understanding population dynamics and informing conservation strategies. Yet obtaining sex ratios in natural populations can be challenging due to logistical, ethical and legal constraints. Environmental DNA (eDNA) has revolutionised non-invasive biodiversity monitoring, but its potential for assessing demographic parameters remains largely unexplored. Here we present an eDNA-based method to monitor sex ratios of populations by quanti",133,{"programme":8,"total":732,"withPiName":732,"firstYear":733,"lastYear":734,"countryCount":735,"perYear":736,"topInstitutions":786,"topCountries":829},788,2008,2026,33,[737,739,742,744,747,750,753,756,759,762,765,768,771,774,777,780,783,784],{"year":733,"count":738},1,{"year":740,"count":741},2009,2,{"year":743,"count":738},2011,{"year":745,"count":746},2012,3,{"year":748,"count":749},2013,5,{"year":751,"count":752},2014,6,{"year":754,"count":755},2015,15,{"year":757,"count":758},2016,41,{"year":760,"count":761},2017,58,{"year":763,"count":764},2018,114,{"year":766,"count":767},2019,28,{"year":769,"count":770},2020,39,{"year":772,"count":773},2021,34,{"year":775,"count":776},2022,37,{"year":778,"count":779},2023,66,{"year":781,"count":782},2024,116,{"year":13,"count":730},{"year":734,"count":785},89,[787,789,791,793,795,796,797,799,801,803,804,805,807,809,811,812,814,816,817,819,821,822,823,825,826],{"name":261,"count":788},63,{"name":20,"count":790},60,{"name":144,"count":792},52,{"name":81,"count":794},40,{"name":32,"count":776},{"name":403,"count":767},{"name":204,"count":798},25,{"name":48,"count":800},19,{"name":374,"count":802},17,{"name":61,"count":802},{"name":250,"count":802},{"name":310,"count":806},16,{"name":11,"count":808},14,{"name":426,"count":810},12,{"name":631,"count":810},{"name":244,"count":813},11,{"name":340,"count":815},8,{"name":174,"count":815},{"name":165,"count":818},7,{"name":820,"count":818},"University of Twente",{"name":282,"count":752},{"name":335,"count":752},{"name":824,"count":752},"Tilburg University",{"name":128,"count":749},{"name":827,"count":828},"Amsterdam University Medical Centers",4,[830,832,834,836,838,840,842,844,846,847,849,850,852,853,854,856,857,858,860,862,864,865,867,869,870],{"name":12,"count":831},558,{"name":26,"count":833},30,{"name":115,"count":835},27,{"name":55,"count":837},21,{"name":232,"count":839},13,{"name":122,"count":841},9,{"name":843,"count":841},"CH",{"name":845,"count":815},"IT",{"name":716,"count":818},{"name":848,"count":749},"AU",{"name":75,"count":749},{"name":851,"count":749},"DK",{"name":294,"count":749},{"name":363,"count":828},{"name":855,"count":828},"BR",{"name":489,"count":746},{"name":157,"count":741},{"name":859,"count":741},"PL",{"name":861,"count":741},"SE",{"name":863,"count":741},"SG",{"name":68,"count":741},{"name":866,"count":738},"AE",{"name":868,"count":738},"AR",{"name":433,"count":738},{"name":871,"count":738},"CL"]