[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"grant-mrc-ukri-mrc-proof-of-concept-2026-11":3,"similar-mrc-ukri-mrc-proof-of-concept-2026-11":36},{"id":4,"name":5,"funder":6,"link":7,"budget":8,"budget_min_eur":9,"budget_max_eur":9,"deadline":10,"deadline_note":11,"duration":12,"trl":9,"relevance":9,"why_relevant":9,"early_career":13,"consortium":14,"first_seen":15,"last_updated":9,"update_note":9,"status":16,"stages":17,"call_frequency":9,"next_call_expected":9,"source_url":7,"created_at":18,"updated_at":19,"eligible_countries":20,"description":22,"seo_summary":23,"links":24},"mrc-ukri-mrc-proof-of-concept-2026-11","MRC Proof of Concept","MRC (UKRI)","https:\u002F\u002Fwww.ukri.org\u002Fopportunity\u002Fmrc-proof-of-concept-stage-two\u002F","No limit stated; 80% FEC funded (100% for permitted exceptions)",null,"2026-11-04T00:00:00.000Z","4:00pm UK time; stage two only — invitation required following successful stage one","No limit; justified by proposed work",false,"No","2026-07-12T00:00:00.000Z","open","2-stage: stage one application → invited stage two application","2026-07-12T05:59:49.105Z","2026-07-12T07:07:40.751Z",[21],"GB","Stage two (invitation only) for academically-led translational health research: prevention, diagnosis, prognosis or treatment of significant health needs, or research tools improving intervention development. Covers early prototype to phase 2a clinical studies. UK lead organisation required; international co-leads eligible up to 30% of total costs (HIC\u002FIndia\u002FChina). 80% FEC funded.","{\"summary\":\"The MRC Proof of Concept scheme funds academically-led translational health research from early prototype through phase 2a clinical studies, with 80% Full Economic Costing (100% for permitted exceptions). Applications are two-stage, with stage two by invitation only following successful stage one; funding covers prevention, diagnosis, prognosis, or treatment of significant health needs, or research tools supporting intervention development. The lead organisation must be UK-based, though international co-leads from high-income countries, India, or China may participate up to 30% of total costs.\",\"meta_description\":\"MRC Proof of Concept funds translational health research from prototype to phase 2a studies, 80% FEC, UK-led with international partners eligible, deadline 4 November 2026, from UKRI.\",\"who_should_apply\":[\"Academic researchers with promising early-stage translational research ready to prototype or early clinical validation\",\"UK host institution as lead; international co-investigators from HIC, India, or China welcome up to 30% of costs\",\"Translational health projects addressing prevention, diagnosis, prognosis, treatment of significant health needs, or intervention-development tools\",\"Teams capable of managing early-to-mid-stage clinical development or technology prototype work\"],\"key_dates\":[\"Stage one deadline: verify on MRC website (stage two invitation-only follows successful stage one)\",\"Stage two deadline: 4 November 2026, 4:00pm UK time\",\"Project duration justified by proposed work; no fixed maximum\"],\"tips\":[\"Stage one is competitive and filters heavily, clarity and feasibility matter more than depth; signal your path to stage two early.\",\"Budget 80% FEC as baseline unless your research qualifies for 100% FEC exceptions (clarify eligibility before submission).\",\"If including international co-leads, keep their total contribution transparent and capped at 30%; this simplifies both review and management.\"],\"faq\":[{\"q\":\"What does the MRC Proof of Concept scheme fund?\",\"a\":\"Academically-led translational health research covering prevention, diagnosis, prognosis, or treatment of significant health needs, plus research tools for intervention development, from early prototype through phase 2a clinical studies.\"},{\"q\":\"What is the funding rate for MRC Proof of Concept?\",\"a\":\"80% Full Economic Costing (FEC); 100% FEC is available for certain permitted exceptions.\"},{\"q\":\"Is MRC Proof of Concept two-stage?\",\"a\":\"Yes, stage one is open; successful applicants are invited to submit stage two by the November deadline.\"},{\"q\":\"Can international researchers apply for MRC Proof of Concept?\",\"a\":\"International co-leads are eligible up to 30% of total costs if based in high-income countries, India, or China; the lead organisation must be UK-based.\"},{\"q\":\"How long is an MRC Proof of Concept project?\",\"a\":\"Project duration is not fixed; it is justified by the proposed work and scope.\"}],\"tags\":[\"translational-research\",\"clinical-trials\",\"mrc\",\"ukri\",\"proof-of-concept\",\"early-stage-innovation\",\"uk-lead\"]}",{"matchedProgram":9,"resourceSlug":25,"relatedGuides":26,"countryHubs":27,"domainHubs":31,"closingMonth":32,"hasRelated":35,"hasBrowseRelated":35},"ukri",[],[28],{"slug":29,"demonym":30},"gb","UK researchers",[],{"slug":33,"label":34},"2026-11","November 2026",true,{"grants":37},[38,43,46,50,54],{"id":39,"name":40,"funder":6,"deadline":41,"budget":42},"mrc-ukri-early-independence-clinician-scientist-fellowship-2026-09","Early Independence Clinician Scientist Fellowship","2026-09-02T00:00:00.000Z","No upper limit; 80% FEC funded",{"id":44,"name":45,"funder":6,"deadline":41,"budget":9},"mrc-ukri-capacity-building-clinical-research-training-fello-2026-09","Capacity Building Clinical Research Training Fellowship (CRTF)",{"id":47,"name":48,"funder":6,"deadline":49,"budget":9},"mrc-ukri-mrc-centre-of-research-excellence-round-four-invit-2026-09","MRC Centre of Research Excellence Round Four – Invited Full Application","2026-09-10T00:00:00.000Z",{"id":51,"name":52,"funder":6,"deadline":53,"budget":42},"mrc-ukri-early-independence-career-development-fellowship-2026-09","Early Independence Career Development Fellowship","2026-09-15T00:00:00.000Z",{"id":55,"name":56,"funder":6,"deadline":57,"budget":9},"mrc-ukri-mrc-experimental-medicine-new-investigator-award-2026-10","MRC Experimental Medicine – New Investigator Award","2026-10-07T00:00:00.000Z"]