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ALSF

Research Accelerating RUNX1 Exploration (RARE) Grant

Up to $250,0002 years

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The ALSF Research Accelerating RUNX1 Exploration (RARE) Grant funds up to $250,000 over two years for research aimed at developing therapies for RUNX1-familial platelet disorder (RUNX1-FPD). The call prioritizes projects targeting interception of the transition from clonal hematopoiesis to MDS/AML, or prevention of malignancy before clonal hematopoiesis develops. This is a disease-specific, high-impact funding stream for researchers working on a rare but clinically urgent genetic disorder.

Details

Funder ALSF
Budget Up to $250,000
Duration 2 years
Consortium No

Eligibility & scope

Funds research aimed at developing therapies for RUNX1-familial platelet disorder (RUNX1-FPD), specifically targeting interception of the transition from clonal hematopoiesis to MDS/AML or prevention of cancer before clonal hematopoiesis. Currently open for applications.

Who Should Apply

  • Researchers focused on RUNX1-familial platelet disorder or clonal hematopoiesis transitions
  • Projects with a translational or therapeutic development aim
  • Scientists at academic institutions, including MD/PhD clinician-scientists
  • Teams targeting interception or prevention of MDS/AML progression

Key Dates

  • Applications currently open; verify deadline on ALSF website
  • Two-year project duration

Tips for Applicants

  • Frame your project around the funder's specific priorities: early interception or prevention, not just treatment after malignancy onset.
  • Include mechanistic detail on RUNX1 biology and how your approach targets the clonal hematopoiesis-to-MDS/AML transition specifically.
  • Emphasize clinical relevance and pathway to therapeutic translation; ALSF prioritizes projects with near-term translational potential.

Frequently Asked Questions

How much does the ALSF RARE Grant award?

Up to $250,000 over a two-year project period.

What research areas does the ALSF RARE Grant fund?

Research aimed at developing therapies for RUNX1-familial platelet disorder, with priority given to projects targeting interception of clonal hematopoiesis-to-MDS/AML progression or prevention before clonal hematopoiesis develops.

Is the ALSF RARE Grant currently accepting applications?

Yes, applications are currently open; verify the submission deadline on the ALSF website.

runx1-familial-platelet-disordermds-amlalsfclonal-hematopoiesistranslational-researchtherapeutic-developmentcancer-prevention

Summary generated by AI based on published grant information. Always verify details on the funder's website.

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