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The Mark Foundation for Cancer Research

Endeavor Award

$3,000,000 over 3 years3 years

Next cycle not yet announced — 'Stay tuned for the announcement of our next Endeavor Awards cycle!'

Last updated:

No deadline is on file for this call. Check The Mark Foundation for Cancer Research's own call page for the current round's status before you plan around it.

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The Endeavor Award from The Mark Foundation for Cancer Research funds collaborative cancer research teams of 3-9 investigators with up to $3 million over three years. Teams must include a principal investigator and 2-8 co-PIs from non-profit academic or research institutions, with all applicants holding independent faculty appointments. Basic, translational, and clinical projects are eligible, and there are no citizenship or geography restrictions.

Details

Funder The Mark Foundation for Cancer Research
Budget $3,000,000 over 3 years
Duration 3 years
Consortium Required — 1 PI and 2–8 co-PIs (teams of 3–9 investigators total) from non-profit academic/research institutions
Application 2-stage: LOI → full proposal (finalists asked to discuss funding overlap)
Frequency Annual

Eligibility & scope

Supports multidisciplinary cancer research teams (1 PI + 2–8 co-PIs) tackling prevention, diagnosis, or treatment challenges. Applicants must hold an independent faculty appointment (tenure-track or equivalent) at a non-profit academic/research institution; no citizenship or geography restrictions. Indirect costs capped at 10% of direct costs. Proposed projects must not be supported by other funding sources.

Who Should Apply

  • •Independent faculty members (tenure-track or equivalent) at non-profit academic or research institutions
  • •Lead investigators ready to convene a collaborative team of 2-8 co-PIs
  • •Multi-investigator cancer research teams spanning basic, translational, or clinical approaches
  • •Researchers seeking to pool expertise across complementary research areas within a single funding mechanism

Key Dates

  • •Annual call cycle; next deadline not yet announced, check The Mark Foundation website for announcement
  • •Letter of Intent submission via online grants portal
  • •Three-year project duration

Tips for Applicants

  • ✓The consortium is mandatory and a strategic choice: co-PI selection signals the scientific breadth of your proposal. Ensure each co-PI's independence and distinct contribution are clear.
  • ✓Indirect costs are capped at 10% of direct costs, budget carefully to avoid leaving money on the table or triggering overages. The funder's revenue-sharing IP terms apply; flag IP concerns upfront.
  • ✓The LOI stage filters for fit and feasibility; finalists then discuss funding overlap, so align the team's funding plan early and be explicit about how each investigator's other grants complement, not duplicate, the Endeavor Award scope.

Frequently Asked Questions

How much does the Endeavor Award fund?

Up to $3 million over three years for a collaborative team.

Who can apply for the Endeavor Award?

Independent faculty members (tenure-track or equivalent) at non-profit academic or research institutions, organized into a team of 3-9 investigators (1 PI + 2-8 co-PIs). No citizenship or geography restrictions apply.

Is the Endeavor Award consortium required?

Yes, applicants must form a multi-investigator team with a single PI and 2-8 co-PIs; single-investigator proposals are not eligible.

What indirect cost rate applies to the Endeavor Award?

Indirect costs are capped at 10% of direct costs; higher institutional rates are not permitted.

cancer-researchmark-foundationcollaborativefacultyconsortium-requiredtranslational-researchthree-year
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