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Cancer Research Institute

Lloyd J. Old STAR Program

$1.25M over 5 years + up to 10% indirect costs| Deadline: 15 January 2027 (in 81 days)|5 years

23:59 Eastern Time

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Catalog updated: .

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Closes 15 Jan 2027. Add it to your calendar, then see what else you're eligible for. Check my fit for this call →

The Lloyd J. Old STAR Program provides up to $1.25 million over five years for mid-career cancer immunotherapy researchers to pursue high-risk, high-reward projects. Eligible applicants are tenure-track assistant professors with at least three years in role, or associate professors within their first three years, holding an MD, PhD, or MD/PhD and committing at least 80% time to research. The programme is open globally to researchers hosted at non-profit medical schools and research centres.

Details

Funder Cancer Research Institute
Budget $1.25M over 5 years + up to 10% indirect costs
Deadline 15 January 2027
Duration 5 years
Consortium No - individual applicant
Application Single stage application; invited interview for shortlisted candidates (Spring 2027)
Frequency Annual

Eligibility & scope

For mid-career scientists (tenure-track assistant professors with ≥3 years in role or associate professors with ≤3 years) holding an MD, PhD, or MD/PhD, committing ≥80% time to research. No citizenship restrictions; research may be conducted at non-profit medical schools/research centers in the US or abroad, but not at for-profit institutions.

Who Should Apply

  • •Tenure-track assistant professors with 3+ years in role, or associate professors within first 3 years
  • •Researchers with MD, PhD, or MD/PhD degree
  • •Applicants committing minimum 80% time to research
  • •Hosted at non-profit medical schools or research centres (US or internationally)
  • •Cancer immunotherapy projects with significant scientific risk and potential reward

Key Dates

  • •Deadline: 15 January 2027, 11:59 p.m. Eastern Time
  • •Two-stage: initial application, then invited virtual interview in Spring 2027
  • •Five-year project duration

Tips for Applicants

  • ✓Emphasise the high-risk/high-reward framing explicitly, CRI funds conceptually novel immunotherapy approaches, not incremental extensions.
  • ✓Include institutional verification of your tenure-track status and research-time allocation; panel confirms eligibility early.
  • ✓Virtual interview panel will probe feasibility of ambitious aims; prepare a clear risk-mitigation narrative.

Frequently Asked Questions

Who is eligible for the Lloyd J. Old STAR Program?

Tenure-track assistant professors with at least 3 years in role, or associate professors within their first 3 years, holding an MD, PhD, or MD/PhD, with at least 80% time commitment to research. Host institution must be a non-profit medical school or research centre (US or abroad); for-profit institutions and adjunct/acting positions are not eligible.

How much does the Lloyd J. Old STAR Program provide?

Up to $1.25 million over five years, plus up to 10% indirect costs.

When is the Lloyd J. Old STAR Program deadline?

15 January 2027, 11:59 p.m. Eastern Time. If the deadline falls on a weekend, applications are accepted until the end of the following Monday.

What type of research does the Lloyd J. Old STAR Program fund?

High-risk, high-reward cancer immunotherapy research led by mid-career scientists.

Is the Lloyd J. Old STAR Program interview required?

Yes, selected applicants advance to a virtual interview in Spring 2027 as the second stage of evaluation.

cancer-immunotherapymid-careerhigh-risk-researchcrius-and-internationalfive-year-grant
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