ChadTough DIPG Foundation
Game Changer Grant
LOI due; call opens 16 October 2026
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The Game Changer Grant from ChadTough DIPG Foundation funds hypothesis-driven research into DIPG/DMG (diffuse intrinsic pontine glioma/diffuse midline glioma), offering up to $600,000 over three years ($200,000/year). The call targets researchers working on major unsolved challenges in these pediatric brain tumors, with applications proceeding through a letter of intent before a full proposal is invited. ChadTough runs this program annually via Proposal Central.
Details
| Funder | ChadTough DIPG Foundation |
| Budget | Up to $600,000 over 3 years ($200,000/year) |
| Deadline | 11 January 2027 |
| Duration | 3 years |
| Application | LOI → invitation for full submission (24 February 2027) → full application (31 March 2027) → award (June 2027) |
| Frequency | Annual |
| Next round | 2026-10 |
Eligibility & scope
Funds hypothesis-driven, innovative research projects aiming for groundbreaking discoveries in DIPG/DMG. Submitted via Proposal Central.
Who Should Apply
- •Researchers proposing hypothesis-driven, innovative projects on DIPG or DMG
- •Investigators with projects addressing major unsolved challenges in these pediatric brain cancers
- •Teams prepared for a multi-year, multi-stage funding process via Proposal Central
Key Dates
- •Call opens 16 October 2026; LOI due 11 January 2027
- •Full application due 31 March 2027, with award start 1 August 2027
- •Three-year project duration, up to $200,000 per year
Tips for Applicants
- ✓The LOI stage is a gating filter before full submission is invited, make the hypothesis and potential impact on DIPG/DMG unmistakably clear early on.
- ✓Frame the project around a specific major challenge in the field rather than incremental extension of existing work, since the call emphasizes groundbreaking discovery.
- ✓Submit through Proposal Central and track the LOI-to-full-application timeline carefully, as only invited applicants proceed to the March full proposal deadline.
Frequently Asked Questions
How much does the Game Changer Grant pay?
Up to $600,000 total over three years, capped at $200,000 per year.
When is the Game Changer Grant deadline?
The LOI is due 11 January 2027, with the call opening 16 October 2026; invited full applications are due 31 March 2027.
What research does the Game Changer Grant fund?
It funds hypothesis-driven, innovative research projects addressing major challenges in DIPG/DMG with potential for groundbreaking discoveries.
Is the Game Changer Grant a multi-stage application?
Yes, applicants submit a letter of intent first, and only those invited proceed to a full application.
Does ChadTough DIPG Foundation run this grant every year?
Yes, the Game Changer Grant is an annual call, with the next round expected to open October 2026.
Summary generated by AI based on published grant information. Always verify details on the funder's website.
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