ChadTough DIPG Foundation
Game Changer Grant
LOI due 2027-01-11; invitation for full submission 2027-02-24; full application due 2027-03-31. Opens October 16, 2026.
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The Game Changer Grant funds hypothesis-driven research projects tackling major challenges in DIPG and DMG (diffuse intrinsic pontine glioma and diffuse midline glioma), with up to $600,000 over three years available per project. This call is open to researchers with innovative approaches to these aggressive pediatric brain cancers, with a focus on groundbreaking discoveries. The ChadTough DIPG Foundation runs this programme annually with a two-stage review process.
Details
| Funder | ChadTough DIPG Foundation |
| Budget | Up to $600k over 3 years (max $200k/year) |
| Deadline | 31 March 2027 |
| Duration | 3 years |
| Application | 2-stage: LOI (2027-01-11) → invited full application (2027-03-31) |
| Frequency | Annual |
| Next round | 2026-10 |
Eligibility & scope
Funds hypothesis-driven, innovative research projects addressing major challenges in DIPG/DMG with potential for groundbreaking discoveries. Focused on DIPG/DMG (diffuse intrinsic pontine glioma / diffuse midline glioma). Applications submitted via Proposal Central.
Who Should Apply
- •Researchers with hypothesis-driven, innovative projects targeting DIPG or DMG biology
- •Academic and clinical researchers focused on pediatric brain cancer
- •Applicants capable of delivering results within three years and $600k total budget
- •Teams with potential to advance the field toward clinical translation
Key Dates
- •Letter of Intent due 11 January 2027
- •Invited full applications due 31 March 2027
- •Three-year project duration
Tips for Applicants
- ✓Frame your research around a single major challenge in DIPG/DMG biology; the foundation prioritises hypothesis-driven work with clear translational potential.
- ✓The LOI is highly competitive; use the 2-page format to demonstrate novelty and feasibility, not depth of preliminary data.
- ✓Keep annual budget planning transparent, flag cost distribution across years and explain any year-to-year variation in your budget narrative.
Frequently Asked Questions
How much funding does the Game Changer Grant provide?
Up to $600,000 over three years, with a maximum of $200,000 per year.
What is the application timeline for the Game Changer Grant?
The call opens 16 October 2026, with a Letter of Intent deadline 11 January 2027, followed by invited full applications due 31 March 2027.
Who can apply for the Game Changer Grant?
Researchers with hypothesis-driven, innovative projects addressing major challenges in DIPG or DMG at academic and clinical institutions.
Is the Game Changer Grant recurring?
Yes, the ChadTough DIPG Foundation runs this programme annually, with the next round opening in October 2026.
Summary generated by AI based on published grant information. Always verify details on the funder's website.
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