KWF
Validation of Biomarkers 2027
Pre-proposal deadline: 20 October 2026, 12:00 noon. Full proposal deadline: 23 February 2027, 12:00 noon.
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The KWF Validation of Biomarkers 2027 call funds clinical validation of known oncology biomarkers (technology-readiness level 5-6) for routine clinical use, with budgets of €0.8-2 million per project over 2-5 years. The call requires a multidisciplinary consortium of at least four parties, including a biostatistician and health-technology-assessment expert, plus mandatory patient involvement; public, private partnerships and co-funding are encouraged. This annual call emphasizes regulatory strategy, reimbursement pathways, and implementation planning alongside validation science.
Details
| Funder | KWF |
| Budget | €0.8M–€2M per proposal |
| Deadline | 20 October 2026 |
| Duration | 2–5 years |
| Consortium | Required — minimum 4 participating parties (multidisciplinary consortium; private partners allowed) |
| Application | 2-stage: pre-proposal (opens 25 Aug 2026, closes 20 Oct 2026) → full proposal (opens 15 Dec 2026, closes 23 Feb 2027) → interviews May 2027 → funding decision June 2027 |
| TRL | 5-6 |
| Frequency | Annual |
| Eligible countries | NL |
Eligibility & scope
Clinical validation of known oncology biomarkers (TRL5/6) for use in daily clinical practice. Requires multidisciplinary consortium of ≥4 parties including biostatistician and HTA expert; patient involvement mandatory. AI-component projects must engage the AI4HEALTH consortium. Public-private collaborations encouraged with co-funding. Dutch Cancer Society (KWF) call; host institutions likely Dutch-based.
Who Should Apply
- •Multidisciplinary teams of ≥4 parties: clinicians, researchers, biostatisticians, HTA specialists, and/or industry partners
- •Researchers based at Dutch academic hospitals, research institutes, or eligible private-sector organisations
- •Projects focused on clinical validation (TRL 5-6) of existing oncology biomarkers for diagnostic or prognostic use
- •Teams with demonstrable patient and patient-association involvement in consortium planning
- •Public, private collaborative consortia with co-funding are particularly competitive
Key Dates
- •Pre-proposal deadline: 20 October 2026, 12:00 noon; full proposal deadline: 23 February 2027, 12:00 noon
- •Two-stage process with shortlist interviews in May 2027 and funding decision in June 2027
- •Project duration: 2-5 years
Tips for Applicants
- ✓Consortium composition is gating: ensure your four-plus parties span clinical, statistical, regulatory, and HTA expertise; weak HTA or missing biostatistician will score poorly.
- ✓Lead with the regulatory and reimbursement pathway as a co-equal pillar to the clinical validation science; KWF explicitly scores implementation readiness.
- ✓AI-component projects must declare early engagement with the AI4HEALTH consortium; omission is a disqualifier, not a weakness to address in revision.
Frequently Asked Questions
What budget can I request for the Validation of Biomarkers 2027 call?
Projects receive €0.8-2 million per proposal. Consortium size, complexity, and the scope of the validation study determine where in that range your project sits.
Is a consortium required for Validation of Biomarkers 2027?
Yes, you must assemble a minimum of four participating parties, including a biostatistician and HTA expert; public, private partnerships and industry co-funding are encouraged.
Do AI-component projects have special requirements?
Yes, projects integrating artificial intelligence must engage the AI4HEALTH consortium early; this is a mandatory component, not optional.
How long does a project last under Validation of Biomarkers 2027?
Project duration is 2-5 years, depending on the scope and complexity of the biomarker validation.
What does the pre-proposal stage require?
The pre-proposal (due 20 October 2026) is a first competitive gate; shortlisted applicants receive feedback and are invited to submit a full proposal by 23 February 2027.
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Summary generated by AI based on published grant information. Always verify details on the funder's website.
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