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SNSF

Investigator Initiated Clinical Trials (IICT)

Not specified (PPI Preparatory Grant up to CHF 5,000 separately available)| Deadline: 3 November 2026 (in 9 days)|Up to 5 years

Full proposal due 3 November 2026, 17:00 Swiss local time. Letter of intent due 26 May 2026, 17:00 Swiss local time (past). PPI Preparatory Grant application also due 26 May 2026.

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The SNSF Investigator Initiated Clinical Trials programme funds randomised controlled trials (RCTs) addressing unmet medical and societal needs, with project duration up to five years plus an optional one-year preparation phase. Applicants must be based at eligible Swiss institutions and lead a multicentric trial with a research team of up to five persons. The call requires patient and public involvement documentation and excludes pilot studies, observational designs, and industry-driven trials.

Details

Funder SNSF
Budget Not specified (PPI Preparatory Grant up to CHF 5,000 separately available)
Deadline 3 November 2026
Duration Up to 5 years
Consortium Required — research group of up to 5 persons in a multicentric setting; recruiting centres must confirm participation in writing
Application 2-stage: letter of intent (26 May 2026) → full proposal (3 November 2026)
Frequency Annual
Eligible countries CH

Eligibility & scope

Supports randomised controlled clinical trials (RCTs) of high scientific quality addressing unmet medical/societal needs, not in industry focus. Applicants must be natural persons meeting SNSF eligibility requirements, affiliated with Swiss institutions, forming a research group. Excludes pilot, proof-of-concept, observational, and preclinical studies. Patient and public involvement (PPI) is required. A PPI preparatory grant of up to CHF 5,000 is available alongside the letter of intent.

Who Should Apply

  • •Researchers based at eligible Swiss institutions
  • •Clinical investigators leading or co-leading a multicentric RCT
  • •Trials addressing unmet medical or societal needs with patient relevance
  • •Research teams of up to five persons with commitment to patient and public involvement

Key Dates

  • •Letter of intent due 26 May 2026, 17:00 Swiss time (two-stage application)
  • •Full proposal due 3 November 2026, 17:00 Swiss time
  • •Project duration up to five years, with optional 12-month preparation phase

Tips for Applicants

  • ✓Patient and public involvement (PPI) documentation is mandatory, plan and budget this explicitly in your proposal.
  • ✓The multicentric requirement is gating; single-site trials are ineligible regardless of design quality.
  • ✓Industry cannot be the driver of the research question, but industry partnerships on defined terms are permitted; clarify roles upfront.

Frequently Asked Questions

What types of clinical trials does SNSF support under this call?

Randomised controlled trials (RCTs) addressing unmet medical or societal needs. Pilot, proof-of-concept (phase I/IIa), observational, and industry-driven studies are excluded.

How long can an SNSF Investigator Initiated Clinical Trial project last?

Up to five years, with an optional preparation phase of up to 12 months.

Do I need a multicentric setting for SNSF Investigator Initiated Clinical Trials?

Yes, a multicentric setting is a mandatory requirement for all proposals.

Can non-Swiss researchers apply for SNSF Investigator Initiated Clinical Trials?

No, applicants must be based at eligible Swiss institutions to be eligible.

snsfclinical-trialsrctsswitzerlandmulticentricpatient-involvementtranslational

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